4JAYA

Crystal structure of p. aeruginosa murb in complex with nadp+
Total Genus 99
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
338
structure length
338
Chain Sequence
b'SLELQEHCSLKPYNTFGIDVRARLLAHARDEADVREALALARERGLPLLVIGGGSNLLLTRDVEALVLRMASQGRRIVSDAADSVLVEAEAGEAWDPFVQWSLERGLAGLENLSLIPGTVGAAPMQNIGAYGVELKDVFDSLTALDRQDGTLREFDRQACRFGYRDSLFKQEPDRWLILRVRLRLTRRERLHLDYGPVRQRLEEEGIASPTARDVSRVICAIRREKLPDPAVLGNAGSFFKNPLVDATQAERLRQAFPDLVGYPQADGRLKLAAGWLIDKGGWKGFRDGPVGVHAQQALVLVNHGGATGAQVRALAERIQEDVRRRFGVELEPEPNLY'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates.
pubmed doi rcsb
molecule keywords UDP-N-acetylenolpyruvoylglucosamine reductase
source organism Pseudomonas aeruginosa
molecule tags Oxidoreductase
total genus 99
structure length 338
sequence length 338
chains with identical sequence B, C, D
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2013-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4jayA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4jayA02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 4jayA03
4PWCA 1ZR6A 5FXDA 4ML8A 3HRDC 3S1CA 3KJMA 3PM9A 5HHZA 1N61C 2P4PA 3AMZA 2OAIA 5FXEA 1ZXIC 1I19A 1QLTA 4PVJA 5HQXA 1DIIA 3BW7A 3AM9A 3DEDA 3NVWB 2VFTA 1T3QC 3B9JB 2E3TA 3D2JA 2W55A 2GQTA 4MLAA 3NS1B 5G5GB 4PVEA 1WVFA 2YVSA 2BVGA 2O3GA 1AHUA 3FWAA 2Q4WA 4UD8A 1W1OA 4XLOA 4DNSA 2NQWA 2RK5A 3W8XA 4PVKA 3S1EA 1V97A 1E8GA 5HMRA 3NVYB 1AHVA 5G5HB 4O95A 2VFSA 2MBRA 1AHZA 5AE1A 2BVHA 4PWBA 1SB3B 3TX1A 1N60C 2R8DA 1W1JA 2BVFA 3D2DA 4PVHA 5ADZA 4EC3A 1N5XA 1FIQB 1JROA 5D79A 3S1DA 1QLUA 3SR6B 1FFVC 1N62C 3TSJA 4JB1A 3W8ZA 2I0KA 2R2ZA 3NVZB 1W1KA 3NRZB 1N63C 3S1FA 3LLBA 3TSHA 2VAOA 3JS8A 5AE3A 2P3HA 1VDVA 1VAOA 1WVEA 1E0YA 2W3SA 2VFVA 1W1RA 2AXRA 2VFUA 4BC9A 2GQUA 3DQ0A 3I99A 3GSYA 3FW8A 4HG0A 4BBYA 3AN1A 1W1SA 2W54A 1F0XA 3W8WA 3LAEA 1W1QA 1DZNA 1RM6B 1WYGA 4OALA 1UXYA 3VTEA 2EXRA 2W3RA 4BC7A 2QPMA 3C0PA 2Q85A 4PZFA 1FFUC 4BCAA 2PLIA 2VFRA 1HSKA 1W1LA 1E8FA 3ETRB 2PLSA 1JRPA 1N5WC 5FXPA 1DIQA 2QKNA 5AE2A 3EUB3 2P13A 5FXFA 1E8HA 3D2HA 3NVVB 4JAYA 1W1MA 3FW7A 1FO4A 3FW9A 4PYTA 1MBTA 1MBBA 4ZOHB
chains in the Genus database with same CATH superfamily
4PWCA 1ZR6A 5FXDA 4ML8A 3HRDC 3S1CA 3KJMA 3PM9A 3RJAA 5HHZA 1N61C 3EJDB 3AMZA 2P4PA 2OAIA 5FXEA 1ZXIC 1I19A 1QLTA 4PVJA 5HQXA 3EJBB 1DIIA 3BW7A 3AM9A 3NVWB 2Y08A 3DEDA 2VFTA 1T3QC 3B9JB 2E3TA 3D2JA 2W55A 2GQTA 3POPA 4MLAA 3NS1B 5G5GB 3HSUA 4PVEA 3EJEB 1WVFA 2YVSA 2BVGA 2UUUA 2O3GA 1AHUA 3FWAA 2Q4WA 2Y3RA 2Y4GA 4UD8A 1W1OA 4XLOA 4DNSA 2NQWA 2RK5A 3W8XA 4PVKA 3S1EA 1V97A 3PQBA 5I1VA 1E8GA 5HMRA 3NVYB 1AHVA 2Y3SA 5G5HB 4O95A 2VFSA 2MBRA 1AHZA 5AE1A 2BVHA 4PWBA 1SB3B 3TX1A 1N60C 5L6GA 2R8DA 1W1JA 2BVFA 3D2DA 4PVHA 5ADZA 4EC3A 5L6FA 1N5XA 1FIQB 1JROA 5D79A 3S1DA 1QLUA 3SR6B 1FFVC 1N62C 3TSJA 4JB1A 3W8ZA 2I0KA 2R2ZA 3NVZB 1W1KA 3NRZB 1N63C 3S1FA 3LLBA 2IPIA 3TSHA 2VAOA 3JS8A 5AE3A 2P3HA 1VDVA 1VAOA 1WVEA 1E0YA 2W3SA 2VFVA 1W1RA 2AXRA 5AWVA 2VFUA 4BC9A 5K8EA 2GQUA 3DQ0A 3I99A 3GSYA 3FW8A 4HG0A 4BBYA 3AN1A 1W1SA 2W54A 1F0XA 3W8WA 3LAEA 1W1QA 1DZNA 1RM6B 1WYGA 4OALA 1UXYA 3VTEA 5I1WA 2EXRA 2W3RA 4BC7A 2QPMA 3C0PA 2Q85A 4PZFA 1FFUC 2WDWA 4BCAA 2PLIA 2VFRA 1HSKA 1W1LA 1E8FA 3ETRB 2PLSA 1JRPA 1N5WC 5FXPA 1DIQA 3RJ8A 2QKNA 5AE2A 3EUB3 2P13A 5FXFA 1E8HA 3D2HA 3NVVB 4JAYA 2UUVA 1W1MA 3FW7A 1FO4A 3FW9A 4PYTA 1MBTA 1MBBA 4ZOHB
chains in the Genus database with same CATH topology
4PWCA 1ZR6A 5FXDA 4ML8A 3HRDC 3S1CA 3KJMA 3PM9A 3RJAA 5HHZA 1N61C 2P4PA 3AMZA 2OAIA 5FXEA 1ZXIC 1I19A 1QLTA 4PVJA 5HQXA 1DIIA 3BW7A 3AM9A 3DEDA 2Y08A 3NVWB 2VFTA 1T3QC 3B9JB 2E3TA 3D2JA 2W55A 2GQTA 3POPA 4MLAA 3NS1B 5G5GB 3HSUA 4PVEA 1WVFA 2YVSA 2BVGA 2UUUA 2O3GA 1AHUA 3FWAA 2Q4WA 2Y3RA 2Y4GA 4UD8A 1W1OA 4XLOA 4DNSA 2NQWA 2RK5A 3W8XA 4PVKA 3S1EA 1V97A 3PQBA 5I1VA 1E8GA 5HMRA 3NVYB 1AHVA 2Y3SA 5G5HB 4O95A 2VFSA 2MBRA 1AHZA 5AE1A 2BVHA 4PWBA 1SB3B 3TX1A 1N60C 5L6GA 2R8DA 1W1JA 2BVFA 3D2DA 4PVHA 5ADZA 4EC3A 5L6FA 1N5XA 1FIQB 1JROA 5D79A 3S1DA 1QLUA 3SR6B 1FFVC 1N62C 3TSJA 4JB1A 3W8ZA 2I0KA 2R2ZA 3NVZB 1W1KA 3NRZB 1N63C 3S1FA 3LLBA 2IPIA 3TSHA 2VAOA 3JS8A 5AE3A 2P3HA 1VDVA 1VAOA 1WVEA 1E0YA 2W3SA 2VFVA 1W1RA 2AXRA 5AWVA 2VFUA 4BC9A 5K8EA 2GQUA 3DQ0A 3I99A 3GSYA 3FW8A 4HG0A 4BBYA 3AN1A 1W1SA 2W54A 1F0XA 3W8WA 3LAEA 1W1QA 1DZNA 1RM6B 1WYGA 4OALA 1UXYA 3VTEA 5I1WA 2EXRA 2W3RA 4BC7A 2QPMA 3C0PA 2Q85A 4PZFA 1FFUC 2WDWA 4BCAA 2PLIA 2VFRA 1HSKA 1W1LA 1E8FA 3ETRB 2PLSA 1JRPA 1N5WC 5FXPA 1DIQA 3RJ8A 2QKNA 5AE2A 3EUB3 2P13A 5FXFA 1E8HA 3D2HA 3NVVB 4JAYA 2UUVA 1W1MA 3FW7A 1FO4A 3FW9A 4PYTA 1MBTA 1MBBA 4ZOHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PWC A;  1ZR6 A;  5FXD A;  4ML8 A;  3HRD C;  3S1C A;  3KJM A;  3PM9 A;  5HHZ A;  1N61 C;  2P4P A;  3AMZ A;  2OAI A;  5FXE A;  1ZXI C;  1I19 A;  1QLT A;  4PVJ A;  5HQX A;  1DII A;  3BW7 A;  3AM9 A;  3DED A;  3NVW B;  2VFT A;  1T3Q C;  3B9J B;  2E3T A;  3D2J A;  2W55 A;  2GQT A;  4MLA A;  3NS1 B;  5G5G B;  4PVE A;  1WVF A;  2YVS A;  2BVG A;  2O3G A;  1AHU A;  3FWA A;  2Q4W A;  4UD8 A;  1W1O A;  4XLO A;  4DNS A;  2NQW A;  2RK5 A;  3W8X A;  4PVK A;  3S1E A;  1V97 A;  1E8G A;  5HMR A;  3NVY B;  1AHV A;  5G5H B;  4O95 A;  2VFS A;  2MBR A;  1AHZ A;  5AE1 A;  2BVH A;  4PWB A;  1SB3 B;  3TX1 A;  1N60 C;  2R8D A;  1W1J A;  2BVF A;  3D2D A;  4PVH A;  5ADZ A;  4EC3 A;  1N5X A;  1FIQ B;  1JRO A;  5D79 A;  3S1D A;  1QLU A;  3SR6 B;  1FFV C;  1N62 C;  3TSJ A;  4JB1 A;  3W8Z A;  2I0K A;  2R2Z A;  3NVZ B;  1W1K A;  3NRZ B;  1N63 C;  3S1F A;  3LLB A;  3TSH A;  2VAO A;  3JS8 A;  5AE3 A;  2P3H A;  1VDV A;  1VAO A;  1WVE A;  1E0Y A;  2W3S A;  2VFV A;  1W1R A;  2AXR A;  2VFU A;  4BC9 A;  2GQU A;  3DQ0 A;  3I99 A;  3GSY A;  3FW8 A;  4HG0 A;  4BBY A;  3AN1 A;  1W1S A;  2W54 A;  1F0X A;  3W8W A;  3LAE A;  1W1Q A;  1DZN A;  1RM6 B;  1WYG A;  4OAL A;  1UXY A;  3VTE A;  2EXR A;  2W3R A;  4BC7 A;  2QPM A;  3C0P A;  2Q85 A;  4PZF A;  1FFU C;  4BCA A;  2PLI A;  2VFR A;  1HSK A;  1W1L A;  1E8F A;  3ETR B;  2PLS A;  1JRP A;  1N5W C;  5FXP A;  1DIQ A;  2QKN A;  5AE2 A;  3EUB 3;  2P13 A;  5FXF A;  1E8H A;  3D2H A;  3NVV B;  4JAY A;  1W1M A;  3FW7 A;  1FO4 A;  3FW9 A;  4PYT A;  1MBT A;  1MBB A;  4ZOH B; 
#chains in the Genus database with same CATH topology
 4PWC A;  1ZR6 A;  5FXD A;  4ML8 A;  3HRD C;  3S1C A;  3KJM A;  3PM9 A;  3RJA A;  5HHZ A;  1N61 C;  3EJD B;  3AMZ A;  2P4P A;  2OAI A;  5FXE A;  1ZXI C;  1I19 A;  1QLT A;  4PVJ A;  5HQX A;  3EJB B;  1DII A;  3BW7 A;  3AM9 A;  3NVW B;  2Y08 A;  3DED A;  2VFT A;  1T3Q C;  3B9J B;  2E3T A;  3D2J A;  2W55 A;  2GQT A;  3POP A;  4MLA A;  3NS1 B;  5G5G B;  3HSU A;  4PVE A;  3EJE B;  1WVF A;  2YVS A;  2BVG A;  2UUU A;  2O3G A;  1AHU A;  3FWA A;  2Q4W A;  2Y3R A;  2Y4G A;  4UD8 A;  1W1O A;  4XLO A;  4DNS A;  2NQW A;  2RK5 A;  3W8X A;  4PVK A;  3S1E A;  1V97 A;  3PQB A;  5I1V A;  1E8G A;  5HMR A;  3NVY B;  1AHV A;  2Y3S A;  5G5H B;  4O95 A;  2VFS A;  2MBR A;  1AHZ A;  5AE1 A;  2BVH A;  4PWB A;  1SB3 B;  3TX1 A;  1N60 C;  5L6G A;  2R8D A;  1W1J A;  2BVF A;  3D2D A;  4PVH A;  5ADZ A;  4EC3 A;  5L6F A;  1N5X A;  1FIQ B;  1JRO A;  5D79 A;  3S1D A;  1QLU A;  3SR6 B;  1FFV C;  1N62 C;  3TSJ A;  4JB1 A;  3W8Z A;  2I0K A;  2R2Z A;  3NVZ B;  1W1K A;  3NRZ B;  1N63 C;  3S1F A;  3LLB A;  2IPI A;  3TSH A;  2VAO A;  3JS8 A;  5AE3 A;  2P3H A;  1VDV A;  1VAO A;  1WVE A;  1E0Y A;  2W3S A;  2VFV A;  1W1R A;  2AXR A;  5AWV A;  2VFU A;  4BC9 A;  5K8E A;  2GQU A;  3DQ0 A;  3I99 A;  3GSY A;  3FW8 A;  4HG0 A;  4BBY A;  3AN1 A;  1W1S A;  2W54 A;  1F0X A;  3W8W A;  3LAE A;  1W1Q A;  1DZN A;  1RM6 B;  1WYG A;  4OAL A;  1UXY A;  3VTE A;  5I1W A;  2EXR A;  2W3R A;  4BC7 A;  2QPM A;  3C0P A;  2Q85 A;  4PZF A;  1FFU C;  2WDW A;  4BCA A;  2PLI A;  2VFR A;  1HSK A;  1W1L A;  1E8F A;  3ETR B;  2PLS A;  1JRP A;  1N5W C;  5FXP A;  1DIQ A;  3RJ8 A;  2QKN A;  5AE2 A;  3EUB 3;  2P13 A;  5FXF A;  1E8H A;  3D2H A;  3NVV B;  4JAY A;  2UUV A;  1W1M A;  3FW7 A;  1FO4 A;  3FW9 A;  4PYT A;  1MBT A;  1MBB A;  4ZOH B; 
#chains in the Genus database with same CATH homology
 4PWC A;  1ZR6 A;  5FXD A;  4ML8 A;  3HRD C;  3S1C A;  3KJM A;  3PM9 A;  3RJA A;  5HHZ A;  1N61 C;  2P4P A;  3AMZ A;  2OAI A;  5FXE A;  1ZXI C;  1I19 A;  1QLT A;  4PVJ A;  5HQX A;  1DII A;  3BW7 A;  3AM9 A;  3DED A;  2Y08 A;  3NVW B;  2VFT A;  1T3Q C;  3B9J B;  2E3T A;  3D2J A;  2W55 A;  2GQT A;  3POP A;  4MLA A;  3NS1 B;  5G5G B;  3HSU A;  4PVE A;  1WVF A;  2YVS A;  2BVG A;  2UUU A;  2O3G A;  1AHU A;  3FWA A;  2Q4W A;  2Y3R A;  2Y4G A;  4UD8 A;  1W1O A;  4XLO A;  4DNS A;  2NQW A;  2RK5 A;  3W8X A;  4PVK A;  3S1E A;  1V97 A;  3PQB A;  5I1V A;  1E8G A;  5HMR A;  3NVY B;  1AHV A;  2Y3S A;  5G5H B;  4O95 A;  2VFS A;  2MBR A;  1AHZ A;  5AE1 A;  2BVH A;  4PWB A;  1SB3 B;  3TX1 A;  1N60 C;  5L6G A;  2R8D A;  1W1J A;  2BVF A;  3D2D A;  4PVH A;  5ADZ A;  4EC3 A;  5L6F A;  1N5X A;  1FIQ B;  1JRO A;  5D79 A;  3S1D A;  1QLU A;  3SR6 B;  1FFV C;  1N62 C;  3TSJ A;  4JB1 A;  3W8Z A;  2I0K A;  2R2Z A;  3NVZ B;  1W1K A;  3NRZ B;  1N63 C;  3S1F A;  3LLB A;  2IPI A;  3TSH A;  2VAO A;  3JS8 A;  5AE3 A;  2P3H A;  1VDV A;  1VAO A;  1WVE A;  1E0Y A;  2W3S A;  2VFV A;  1W1R A;  2AXR A;  5AWV A;  2VFU A;  4BC9 A;  5K8E A;  2GQU A;  3DQ0 A;  3I99 A;  3GSY A;  3FW8 A;  4HG0 A;  4BBY A;  3AN1 A;  1W1S A;  2W54 A;  1F0X A;  3W8W A;  3LAE A;  1W1Q A;  1DZN A;  1RM6 B;  1WYG A;  4OAL A;  1UXY A;  3VTE A;  5I1W A;  2EXR A;  2W3R A;  4BC7 A;  2QPM A;  3C0P A;  2Q85 A;  4PZF A;  1FFU C;  2WDW A;  4BCA A;  2PLI A;  2VFR A;  1HSK A;  1W1L A;  1E8F A;  3ETR B;  2PLS A;  1JRP A;  1N5W C;  5FXP A;  1DIQ A;  3RJ8 A;  2QKN A;  5AE2 A;  3EUB 3;  2P13 A;  5FXF A;  1E8H A;  3D2H A;  3NVV B;  4JAY A;  2UUV A;  1W1M A;  3FW7 A;  1FO4 A;  3FW9 A;  4PYT A;  1MBT A;  1MBB A;  4ZOH B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...