4JAYA

Crystal structure of p. aeruginosa murb in complex with nadp+
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
338
structure length
338
Chain Sequence
SLELQEHCSLKPYNTFGIDVRARLLAHARDEADVREALALARERGLPLLVIGGGSNLLLTRDVEALVLRMASQGRRIVSDAADSVLVEAEAGEAWDPFVQWSLERGLAGLENLSLIPGTVGAAPMQNIGAYGVELKDVFDSLTALDRQDGTLREFDRQACRFGYRDSLFKQEPDRWLILRVRLRLTRRERLHLDYGPVRQRLEEEGIASPTARDVSRVICAIRREKLPDPAVLGNAGSFFKNPLVDATQAERLRQAFPDLVGYPQADGRLKLAAGWLIDKGGWKGFRDGPVGVHAQQALVLVNHGGATGAQVRALAERIQEDVRRRFGVELEPEPNLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-N-acetylenolpyruvoylglucosamine reductase
publication title Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Oxidoreductase
total genus 99
structure length 338
sequence length 338
chains with identical sequence B, C, D
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2013-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4jayA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4jayA02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 4jayA03
4PYTA 4BBYA 1JROA 5ADZA 4HG0A 1DIIA 1VAOA 4BCAA 1E8GA 2R2ZA 4PVKA 3BW7A 4PZFA 3AN1A 3D2JA 2I0KA 4UD8A 2RK5A 1DIQA 3FW9A 3I99A 1N61C 3NRZB 1FO4A 1ZR6A 4PWBA 1V97A 1FFVC 1UXYA 4BC9A 3S1DA 5D79A 2GQUA 2QPMA 3S1CA 1W1LA 2NQWA 4PVJA 2Q4WA 2W55A 1W1OA 3TSHA 1I19A 1QLUA 4DNSA 1T3QC 1WYGA 3D2HA 5G5GB 1MBBA 1RM6B 1AHUA 4JB1A 2YVSA 1N62C 2MBRA 4OALA 3TSJA 3JS8A 2P4PA 3GSYA 1F0XA 4JAYA 1WVEA 3PM9A 4PWCA 4MLAA 2PLSA 4BC7A 3S1FA 2VAOA 3DQ0A 1W1MA 3KJMA 5AE1A 3NVZB 1W1KA 2BVFA 5HHZA 2BVGA 3EUB3 3AMZA 3D2DA 3W8XA 2VFSA 5AE2A 1N5WC 3B9JB 1AHVA 3W8ZA 1HSKA 1W1QA 2AXRA 2GQTA 3NS1B 3NVWB 5FXDA 4EC3A 2P3HA 2Q85A 1JRPA 4PVEA 2W54A 3W8WA 5FXFA 3S1EA 3LLBA 2VFVA 1SB3B 4ML8A 1E8HA 2OAIA 1W1SA 1E0YA 1W1JA 3TX1A 1N63C 3C0PA 5FXPA 4O95A 3VTEA 1MBTA 3FW8A 2VFUA 3FWAA 1E8FA 1WVFA 3SR6B 1AHZA 5AE3A 2E3TA 1ZXIC 1QLTA 2EXRA 2VFRA 3HRDC 5HMRA 3LAEA 1N60C 1VDVA 2PLIA 4ZOHB 2W3SA 3FW7A 3NVYB 2W3RA 3AM9A 2BVHA 2VFTA 2P13A 3ETRB 1FFUC 1W1RA 1DZNA 3DEDA 4PVHA 5G5HB 1FIQB 2QKNA 5FXEA 4XLOA 3NVVB 5HQXA 2O3GA 1N5XA 2R8DA
chains in the Genus database with same CATH superfamily
3HSUA 4PYTA 4BBYA 1JROA 5ADZA 4HG0A 1DIIA 1VAOA 4BCAA 1E8GA 2R2ZA 4PVKA 3BW7A 4PZFA 3AN1A 3D2JA 2I0KA 4UD8A 2RK5A 1DIQA 3FW9A 3I99A 1N61C 3NRZB 1FO4A 1ZR6A 4PWBA 1V97A 1FFVC 1UXYA 4BC9A 3S1DA 5D79A 2GQUA 2QPMA 3S1CA 5K8EA 1W1LA 2NQWA 3POPA 4PVJA 3PQBA 2Q4WA 2W55A 1W1OA 3TSHA 5I1WA 1I19A 1QLUA 4DNSA 2WDWA 1T3QC 1WYGA 3D2HA 5G5GB 1MBBA 1RM6B 1AHUA 4JB1A 2YVSA 1N62C 2MBRA 4OALA 3TSJA 3JS8A 2P4PA 3GSYA 1F0XA 4JAYA 1WVEA 3PM9A 4PWCA 4MLAA 5I1VA 2PLSA 4BC7A 5L6FA 3S1FA 2IPIA 2VAOA 3DQ0A 1W1MA 3EJDB 3KJMA 5L6GA 5AE1A 3NVZB 1W1KA 2BVFA 3EJBB 5HHZA 2BVGA 3EUB3 3AMZA 3D2DA 3W8XA 2VFSA 5AE2A 1N5WC 2Y08A 3RJ8A 2UUVA 2UUUA 3B9JB 1AHVA 3W8ZA 1HSKA 1W1QA 2AXRA 2GQTA 3NS1B 3NVWB 2Y4GA 5FXDA 4EC3A 2P3HA 2Q85A 1JRPA 4PVEA 2W54A 3W8WA 5FXFA 3S1EA 3LLBA 2VFVA 1SB3B 4ML8A 1E8HA 3EJEB 2OAIA 1W1SA 1E0YA 2Y3RA 5AWVA 1W1JA 3TX1A 1N63C 3C0PA 5FXPA 4O95A 3VTEA 1MBTA 3FW8A 2VFUA 3FWAA 1E8FA 1WVFA 3SR6B 2Y3SA 1AHZA 5AE3A 2E3TA 1ZXIC 1QLTA 2EXRA 2VFRA 3HRDC 5HMRA 3RJAA 3LAEA 1N60C 1VDVA 2PLIA 4ZOHB 2W3SA 3FW7A 3NVYB 2W3RA 3AM9A 2BVHA 2VFTA 2P13A 3ETRB 1FFUC 1W1RA 1DZNA 3DEDA 4PVHA 5G5HB 1FIQB 2QKNA 5FXEA 3NVVB 4XLOA 5HQXA 2O3GA 1N5XA 2R8DA
chains in the Genus database with same CATH topology
3HSUA 4PYTA 4BBYA 1JROA 5ADZA 4HG0A 1DIIA 1VAOA 4BCAA 1E8GA 2R2ZA 4PVKA 3BW7A 4PZFA 3AN1A 3D2JA 2I0KA 4UD8A 2RK5A 1DIQA 3FW9A 3I99A 1N61C 3NRZB 1FO4A 1ZR6A 4PWBA 1V97A 1FFVC 1UXYA 4BC9A 3S1DA 5D79A 2GQUA 2QPMA 3S1CA 5K8EA 1W1LA 2NQWA 3POPA 4PVJA 3PQBA 2Q4WA 2W55A 1W1OA 3TSHA 5I1WA 1I19A 1QLUA 4DNSA 2WDWA 1T3QC 1WYGA 3D2HA 5G5GB 1MBBA 1RM6B 1AHUA 4JB1A 2YVSA 1N62C 2MBRA 4OALA 3TSJA 3JS8A 2P4PA 3GSYA 1F0XA 4JAYA 1WVEA 3PM9A 4PWCA 4MLAA 5I1VA 2PLSA 4BC7A 5L6FA 3S1FA 2IPIA 2VAOA 3DQ0A 1W1MA 3KJMA 5L6GA 5AE1A 3NVZB 1W1KA 2BVFA 5HHZA 2BVGA 3EUB3 3AMZA 3D2DA 3W8XA 2VFSA 5AE2A 1N5WC 2Y08A 3RJ8A 2UUVA 2UUUA 3B9JB 1AHVA 3W8ZA 1HSKA 1W1QA 2AXRA 2GQTA 3NS1B 2Y4GA 3NVWB 5FXDA 4EC3A 2P3HA 2Q85A 1JRPA 4PVEA 2W54A 3W8WA 5FXFA 3S1EA 3LLBA 2VFVA 1SB3B 4ML8A 1E8HA 2OAIA 1W1SA 1E0YA 2Y3RA 5AWVA 1W1JA 3TX1A 1N63C 3C0PA 5FXPA 4O95A 3VTEA 1MBTA 3FW8A 2VFUA 3FWAA 1E8FA 1WVFA 3SR6B 2Y3SA 1AHZA 5AE3A 2E3TA 1ZXIC 1QLTA 2EXRA 2VFRA 3HRDC 5HMRA 3RJAA 3LAEA 1N60C 1VDVA 2PLIA 4ZOHB 2W3SA 3FW7A 3NVYB 2W3RA 3AM9A 2BVHA 2VFTA 2P13A 3ETRB 1FFUC 1W1RA 1DZNA 3DEDA 4PVHA 5G5HB 1FIQB 2QKNA 5FXEA 4XLOA 3NVVB 5HQXA 2O3GA 1N5XA 2R8DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PYT A;  4BBY A;  1JRO A;  5ADZ A;  4HG0 A;  1DII A;  1VAO A;  4BCA A;  1E8G A;  2R2Z A;  4PVK A;  3BW7 A;  4PZF A;  3AN1 A;  3D2J A;  2I0K A;  4UD8 A;  2RK5 A;  1DIQ A;  3FW9 A;  3I99 A;  1N61 C;  3NRZ B;  1FO4 A;  1ZR6 A;  4PWB A;  1V97 A;  1FFV C;  1UXY A;  4BC9 A;  3S1D A;  5D79 A;  2GQU A;  2QPM A;  3S1C A;  1W1L A;  2NQW A;  4PVJ A;  2Q4W A;  2W55 A;  1W1O A;  3TSH A;  1I19 A;  1QLU A;  4DNS A;  1T3Q C;  1WYG A;  3D2H A;  5G5G B;  1MBB A;  1RM6 B;  1AHU A;  4JB1 A;  2YVS A;  1N62 C;  2MBR A;  4OAL A;  3TSJ A;  3JS8 A;  2P4P A;  3GSY A;  1F0X A;  4JAY A;  1WVE A;  3PM9 A;  4PWC A;  4MLA A;  2PLS A;  4BC7 A;  3S1F A;  2VAO A;  3DQ0 A;  1W1M A;  3KJM A;  5AE1 A;  3NVZ B;  1W1K A;  2BVF A;  5HHZ A;  2BVG A;  3EUB 3;  3AMZ A;  3D2D A;  3W8X A;  2VFS A;  5AE2 A;  1N5W C;  3B9J B;  1AHV A;  3W8Z A;  1HSK A;  1W1Q A;  2AXR A;  2GQT A;  3NS1 B;  3NVW B;  5FXD A;  4EC3 A;  2P3H A;  2Q85 A;  1JRP A;  4PVE A;  2W54 A;  3W8W A;  5FXF A;  3S1E A;  3LLB A;  2VFV A;  1SB3 B;  4ML8 A;  1E8H A;  2OAI A;  1W1S A;  1E0Y A;  1W1J A;  3TX1 A;  1N63 C;  3C0P A;  5FXP A;  4O95 A;  3VTE A;  1MBT A;  3FW8 A;  2VFU A;  3FWA A;  1E8F A;  1WVF A;  3SR6 B;  1AHZ A;  5AE3 A;  2E3T A;  1ZXI C;  1QLT A;  2EXR A;  2VFR A;  3HRD C;  5HMR A;  3LAE A;  1N60 C;  1VDV A;  2PLI A;  4ZOH B;  2W3S A;  3FW7 A;  3NVY B;  2W3R A;  3AM9 A;  2BVH A;  2VFT A;  2P13 A;  3ETR B;  1FFU C;  1W1R A;  1DZN A;  3DED A;  4PVH A;  5G5H B;  1FIQ B;  2QKN A;  5FXE A;  4XLO A;  3NVV B;  5HQX A;  2O3G A;  1N5X A;  2R8D A; 
#chains in the Genus database with same CATH topology
 3HSU A;  4PYT A;  4BBY A;  1JRO A;  5ADZ A;  4HG0 A;  1DII A;  1VAO A;  4BCA A;  1E8G A;  2R2Z A;  4PVK A;  3BW7 A;  4PZF A;  3AN1 A;  3D2J A;  2I0K A;  4UD8 A;  2RK5 A;  1DIQ A;  3FW9 A;  3I99 A;  1N61 C;  3NRZ B;  1FO4 A;  1ZR6 A;  4PWB A;  1V97 A;  1FFV C;  1UXY A;  4BC9 A;  3S1D A;  5D79 A;  2GQU A;  2QPM A;  3S1C A;  5K8E A;  1W1L A;  2NQW A;  3POP A;  4PVJ A;  3PQB A;  2Q4W A;  2W55 A;  1W1O A;  3TSH A;  5I1W A;  1I19 A;  1QLU A;  4DNS A;  2WDW A;  1T3Q C;  1WYG A;  3D2H A;  5G5G B;  1MBB A;  1RM6 B;  1AHU A;  4JB1 A;  2YVS A;  1N62 C;  2MBR A;  4OAL A;  3TSJ A;  3JS8 A;  2P4P A;  3GSY A;  1F0X A;  4JAY A;  1WVE A;  3PM9 A;  4PWC A;  4MLA A;  5I1V A;  2PLS A;  4BC7 A;  5L6F A;  3S1F A;  2IPI A;  2VAO A;  3DQ0 A;  1W1M A;  3EJD B;  3KJM A;  5L6G A;  5AE1 A;  3NVZ B;  1W1K A;  2BVF A;  3EJB B;  5HHZ A;  2BVG A;  3EUB 3;  3AMZ A;  3D2D A;  3W8X A;  2VFS A;  5AE2 A;  1N5W C;  2Y08 A;  3RJ8 A;  2UUV A;  2UUU A;  3B9J B;  1AHV A;  3W8Z A;  1HSK A;  1W1Q A;  2AXR A;  2GQT A;  3NS1 B;  3NVW B;  2Y4G A;  5FXD A;  4EC3 A;  2P3H A;  2Q85 A;  1JRP A;  4PVE A;  2W54 A;  3W8W A;  5FXF A;  3S1E A;  3LLB A;  2VFV A;  1SB3 B;  4ML8 A;  1E8H A;  3EJE B;  2OAI A;  1W1S A;  1E0Y A;  2Y3R A;  5AWV A;  1W1J A;  3TX1 A;  1N63 C;  3C0P A;  5FXP A;  4O95 A;  3VTE A;  1MBT A;  3FW8 A;  2VFU A;  3FWA A;  1E8F A;  1WVF A;  3SR6 B;  2Y3S A;  1AHZ A;  5AE3 A;  2E3T A;  1ZXI C;  1QLT A;  2EXR A;  2VFR A;  3HRD C;  5HMR A;  3RJA A;  3LAE A;  1N60 C;  1VDV A;  2PLI A;  4ZOH B;  2W3S A;  3FW7 A;  3NVY B;  2W3R A;  3AM9 A;  2BVH A;  2VFT A;  2P13 A;  3ETR B;  1FFU C;  1W1R A;  1DZN A;  3DED A;  4PVH A;  5G5H B;  1FIQ B;  2QKN A;  5FXE A;  3NVV B;  4XLO A;  5HQX A;  2O3G A;  1N5X A;  2R8D A; 
#chains in the Genus database with same CATH homology
 3HSU A;  4PYT A;  4BBY A;  1JRO A;  5ADZ A;  4HG0 A;  1DII A;  1VAO A;  4BCA A;  1E8G A;  2R2Z A;  4PVK A;  3BW7 A;  4PZF A;  3AN1 A;  3D2J A;  2I0K A;  4UD8 A;  2RK5 A;  1DIQ A;  3FW9 A;  3I99 A;  1N61 C;  3NRZ B;  1FO4 A;  1ZR6 A;  4PWB A;  1V97 A;  1FFV C;  1UXY A;  4BC9 A;  3S1D A;  5D79 A;  2GQU A;  2QPM A;  3S1C A;  5K8E A;  1W1L A;  2NQW A;  3POP A;  4PVJ A;  3PQB A;  2Q4W A;  2W55 A;  1W1O A;  3TSH A;  5I1W A;  1I19 A;  1QLU A;  4DNS A;  2WDW A;  1T3Q C;  1WYG A;  3D2H A;  5G5G B;  1MBB A;  1RM6 B;  1AHU A;  4JB1 A;  2YVS A;  1N62 C;  2MBR A;  4OAL A;  3TSJ A;  3JS8 A;  2P4P A;  3GSY A;  1F0X A;  4JAY A;  1WVE A;  3PM9 A;  4PWC A;  4MLA A;  5I1V A;  2PLS A;  4BC7 A;  5L6F A;  3S1F A;  2IPI A;  2VAO A;  3DQ0 A;  1W1M A;  3KJM A;  5L6G A;  5AE1 A;  3NVZ B;  1W1K A;  2BVF A;  5HHZ A;  2BVG A;  3EUB 3;  3AMZ A;  3D2D A;  3W8X A;  2VFS A;  5AE2 A;  1N5W C;  2Y08 A;  3RJ8 A;  2UUV A;  2UUU A;  3B9J B;  1AHV A;  3W8Z A;  1HSK A;  1W1Q A;  2AXR A;  2GQT A;  3NS1 B;  2Y4G A;  3NVW B;  5FXD A;  4EC3 A;  2P3H A;  2Q85 A;  1JRP A;  4PVE A;  2W54 A;  3W8W A;  5FXF A;  3S1E A;  3LLB A;  2VFV A;  1SB3 B;  4ML8 A;  1E8H A;  2OAI A;  1W1S A;  1E0Y A;  2Y3R A;  5AWV A;  1W1J A;  3TX1 A;  1N63 C;  3C0P A;  5FXP A;  4O95 A;  3VTE A;  1MBT A;  3FW8 A;  2VFU A;  3FWA A;  1E8F A;  1WVF A;  3SR6 B;  2Y3S A;  1AHZ A;  5AE3 A;  2E3T A;  1ZXI C;  1QLT A;  2EXR A;  2VFR A;  3HRD C;  5HMR A;  3RJA A;  3LAE A;  1N60 C;  1VDV A;  2PLI A;  4ZOH B;  2W3S A;  3FW7 A;  3NVY B;  2W3R A;  3AM9 A;  2BVH A;  2VFT A;  2P13 A;  3ETR B;  1FFU C;  1W1R A;  1DZN A;  3DED A;  4PVH A;  5G5H B;  1FIQ B;  2QKN A;  5FXE A;  4XLO A;  3NVV B;  5HQX A;  2O3G A;  1N5X A;  2R8D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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