2GQTA

Crystal structure of udp-n-acetylenolpyruvylglucosamine reductase (murb) from thermus caldophilus
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
267
structure length
267
Chain Sequence
EFMRVERVLLKDYTTLGVGGPAELWTVETREELKRATEAPYRVLGNGSNLLVLDEGVPERVIRLAGEFQTYDLKGWVGAGTLLPLLVQEAARAGLSGLEGLLGIPAQVGGAVKMNAGTRFGEMADALEAVEVFHDGAFHVYCPEELGFGYRKSHLPPGGIVTRVRLKLKERPKEEILRRMAEVDRARKGQPKRKSAGCAFKNPPGQSAGRLIDERGLKGLRVGDAMISLEHGNFIVNLGQARAKDVLELVRRVQEELPLELEWEVWP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Thermus caldophilus
pubmed doi rcsb
source organism Thermus caldophilus
molecule tags Oxidoreductase
molecule keywords UDP-N-Acetylenolpyruvylglucosamine Reductase
total genus 76
structure length 267
sequence length 267
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2006-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2gqtA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2gqtA02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 2gqtA03
3C0PA 1FFVC 4MLAA 3JS8A 4UD8A 1DIIA 5AE2A 3BW7A 3D2HA 2P13A 2P4PA 1JROA 1ZXIC 4PVEA 1SB3B 5D79A 2W54A 2W3SA 3HRDC 1WYGA 2Q85A 1MBBA 4JAYA 2W3RA 2YVSA 1W1LA 2W55A 3B9JB 5ADZA 2BVFA 1V97A 1HSKA 4PVKA 1N63C 1UXYA 1I19A 1QLUA 3FW8A 4PZFA 2O3GA 4ML8A 5AE1A 2BVGA 1T3QC 1W1OA 3W8ZA 3PM9A 3TSJA 5FXPA 4DNSA 5AE3A 3S1CA 5FXFA 3FW7A 4BBYA 3VTEA 4O95A 3ETRB 1RM6B 4PWBA 1W1MA 3W8XA 2RK5A 4PYTA 1N5XA 1W1JA 2VFRA 2R2ZA 3S1FA 1W1QA 3TSHA 3AM9A 2AXRA 1W1SA 5FXDA 1N60C 1N62C 5HQXA 1E8GA 3NVYB 4BC9A 2PLSA 1WVFA 1E0YA 2GQTA 2VFSA 3D2DA 2E3TA 3FWAA 3NVZB 1FIQB 1VAOA 2MBRA 1N61C 2BVHA 3FW9A 3LAEA 2Q4WA 2OAIA 1JRPA 3NRZB 4PVJA 1N5WC 4PWCA 2VFUA 3D2JA 3NVVB 3S1EA 1AHVA 2P3HA 2PLIA 3NVWB 3DQ0A 4PVHA 3DEDA 5G5GB 1FO4A 2GQUA 2R8DA 2NQWA 4BCAA 3SR6B 1F0XA 2VFTA 1AHUA 3I99A 1E8FA 2EXRA 5FXEA 3GSYA 4BC7A 4EC3A 1WVEA 2QPMA 3EUB3 1W1RA 1W1KA 1QLTA 2VFVA 2VAOA 1MBTA 1DZNA 1E8HA 4OALA 3TX1A 3W8WA 4HG0A 1DIQA 5G5HB 1AHZA 2I0KA 3LLBA 5HMRA 4ZOHB 1FFUC 3S1DA 5HHZA 3AN1A 3AMZA 3NS1B 2QKNA 1VDVA 1ZR6A 4JB1A 3KJMA 4XLOA
chains in the Genus database with same CATH superfamily
5AWVA 3C0PA 1FFVC 4MLAA 3JS8A 3HSUA 4UD8A 1DIIA 5AE2A 3BW7A 3D2HA 2P13A 2P4PA 1JROA 1ZXIC 4PVEA 1SB3B 3RJAA 5D79A 3EJEB 2W54A 2W3SA 3HRDC 1WYGA 2Q85A 1MBBA 4JAYA 2W3RA 2YVSA 1W1LA 3EJBB 2W55A 3B9JB 5ADZA 2BVFA 1V97A 1HSKA 4PVKA 1N63C 1UXYA 1I19A 1QLUA 3FW8A 4PZFA 2O3GA 4ML8A 5AE1A 2BVGA 1T3QC 1W1OA 3W8ZA 3PM9A 3TSJA 5I1WA 5FXPA 4DNSA 5AE3A 2Y3RA 3S1CA 5FXFA 3FW7A 4BBYA 3VTEA 4O95A 3ETRB 5L6GA 1RM6B 4PWBA 5L6FA 1W1MA 3W8XA 2RK5A 4PYTA 1N5XA 1W1JA 2VFRA 2R2ZA 3S1FA 1W1QA 3TSHA 3RJ8A 3AM9A 2AXRA 1W1SA 3POPA 5FXDA 1N60C 1N62C 5HQXA 2UUUA 2IPIA 1E8GA 3NVYB 4BC9A 2PLSA 1WVFA 1E0YA 2GQTA 2VFSA 3D2DA 2Y4GA 2E3TA 3FWAA 3NVZB 1FIQB 1VAOA 2MBRA 1N61C 2BVHA 3FW9A 3LAEA 2Q4WA 2OAIA 1JRPA 3NRZB 4PVJA 3EJDB 1N5WC 4PWCA 2VFUA 3D2JA 2UUVA 3NVVB 3S1EA 1AHVA 2P3HA 3NVWB 2PLIA 3DQ0A 4PVHA 3DEDA 2Y08A 5G5GB 1FO4A 2GQUA 2R8DA 2NQWA 4BCAA 3SR6B 1F0XA 2VFTA 1AHUA 3I99A 1E8FA 2EXRA 5FXEA 3GSYA 4BC7A 4EC3A 1WVEA 2QPMA 3PQBA 3EUB3 1W1RA 1W1KA 1QLTA 2VFVA 2VAOA 1MBTA 1DZNA 1E8HA 4OALA 3TX1A 3W8WA 4HG0A 1DIQA 5G5HB 1AHZA 2I0KA 3LLBA 5HMRA 4ZOHB 1FFUC 3S1DA 5HHZA 3AN1A 3AMZA 2WDWA 3NS1B 2QKNA 1VDVA 5I1VA 5K8EA 2Y3SA 1ZR6A 4JB1A 3KJMA 4XLOA
chains in the Genus database with same CATH topology
5AWVA 3C0PA 1FFVC 4MLAA 3JS8A 3HSUA 4UD8A 1DIIA 5AE2A 3BW7A 3D2HA 2P13A 2P4PA 1JROA 1ZXIC 4PVEA 1SB3B 3RJAA 5D79A 2W54A 2W3SA 3HRDC 1WYGA 2Q85A 1MBBA 4JAYA 2W3RA 2YVSA 1W1LA 2W55A 3B9JB 5ADZA 2BVFA 1V97A 1HSKA 4PVKA 1N63C 1UXYA 1I19A 1QLUA 3FW8A 4PZFA 2O3GA 4ML8A 5AE1A 2BVGA 1T3QC 1W1OA 3W8ZA 3PM9A 3TSJA 5I1WA 5FXPA 4DNSA 5AE3A 2Y3RA 3S1CA 5FXFA 3FW7A 4BBYA 3VTEA 4O95A 3ETRB 5L6GA 1RM6B 4PWBA 5L6FA 1W1MA 3W8XA 2RK5A 4PYTA 1N5XA 1W1JA 2VFRA 2R2ZA 3S1FA 1W1QA 3TSHA 3RJ8A 3AM9A 2AXRA 1W1SA 3POPA 5FXDA 1N60C 1N62C 5HQXA 2UUUA 2IPIA 1E8GA 3NVYB 4BC9A 2PLSA 1WVFA 1E0YA 2GQTA 2VFSA 3D2DA 2Y4GA 2E3TA 3FWAA 3NVZB 1FIQB 1VAOA 2MBRA 1N61C 2BVHA 3FW9A 3LAEA 2Q4WA 2OAIA 1JRPA 3NRZB 4PVJA 1N5WC 4PWCA 2VFUA 3D2JA 2UUVA 3NVVB 3S1EA 1AHVA 2P3HA 2PLIA 3NVWB 3DQ0A 4PVHA 3DEDA 2Y08A 5G5GB 1FO4A 2GQUA 2R8DA 2NQWA 4BCAA 3SR6B 1F0XA 2VFTA 1AHUA 3I99A 1E8FA 2EXRA 5FXEA 3GSYA 4BC7A 4EC3A 1WVEA 2QPMA 3PQBA 3EUB3 1W1RA 1W1KA 1QLTA 2VFVA 2VAOA 1MBTA 1DZNA 1E8HA 4OALA 3TX1A 3W8WA 4HG0A 1DIQA 5G5HB 1AHZA 2I0KA 3LLBA 5HMRA 4ZOHB 1FFUC 3S1DA 5HHZA 3AN1A 3AMZA 2WDWA 3NS1B 2QKNA 1VDVA 5I1VA 5K8EA 2Y3SA 1ZR6A 4JB1A 3KJMA 4XLOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C0P A;  1FFV C;  4MLA A;  3JS8 A;  4UD8 A;  1DII A;  5AE2 A;  3BW7 A;  3D2H A;  2P13 A;  2P4P A;  1JRO A;  1ZXI C;  4PVE A;  1SB3 B;  5D79 A;  2W54 A;  2W3S A;  3HRD C;  1WYG A;  2Q85 A;  1MBB A;  4JAY A;  2W3R A;  2YVS A;  1W1L A;  2W55 A;  3B9J B;  5ADZ A;  2BVF A;  1V97 A;  1HSK A;  4PVK A;  1N63 C;  1UXY A;  1I19 A;  1QLU A;  3FW8 A;  4PZF A;  2O3G A;  4ML8 A;  5AE1 A;  2BVG A;  1T3Q C;  1W1O A;  3W8Z A;  3PM9 A;  3TSJ A;  5FXP A;  4DNS A;  5AE3 A;  3S1C A;  5FXF A;  3FW7 A;  4BBY A;  3VTE A;  4O95 A;  3ETR B;  1RM6 B;  4PWB A;  1W1M A;  3W8X A;  2RK5 A;  4PYT A;  1N5X A;  1W1J A;  2VFR A;  2R2Z A;  3S1F A;  1W1Q A;  3TSH A;  3AM9 A;  2AXR A;  1W1S A;  5FXD A;  1N60 C;  1N62 C;  5HQX A;  1E8G A;  3NVY B;  4BC9 A;  2PLS A;  1WVF A;  1E0Y A;  2GQT A;  2VFS A;  3D2D A;  2E3T A;  3FWA A;  3NVZ B;  1FIQ B;  1VAO A;  2MBR A;  1N61 C;  2BVH A;  3FW9 A;  3LAE A;  2Q4W A;  2OAI A;  1JRP A;  3NRZ B;  4PVJ A;  1N5W C;  4PWC A;  2VFU A;  3D2J A;  3NVV B;  3S1E A;  1AHV A;  2P3H A;  2PLI A;  3NVW B;  3DQ0 A;  4PVH A;  3DED A;  5G5G B;  1FO4 A;  2GQU A;  2R8D A;  2NQW A;  4BCA A;  3SR6 B;  1F0X A;  2VFT A;  1AHU A;  3I99 A;  1E8F A;  2EXR A;  5FXE A;  3GSY A;  4BC7 A;  4EC3 A;  1WVE A;  2QPM A;  3EUB 3;  1W1R A;  1W1K A;  1QLT A;  2VFV A;  2VAO A;  1MBT A;  1DZN A;  1E8H A;  4OAL A;  3TX1 A;  3W8W A;  4HG0 A;  1DIQ A;  5G5H B;  1AHZ A;  2I0K A;  3LLB A;  5HMR A;  4ZOH B;  1FFU C;  3S1D A;  5HHZ A;  3AN1 A;  3AMZ A;  3NS1 B;  2QKN A;  1VDV A;  1ZR6 A;  4JB1 A;  3KJM A;  4XLO A; 
#chains in the Genus database with same CATH topology
 5AWV A;  3C0P A;  1FFV C;  4MLA A;  3JS8 A;  3HSU A;  4UD8 A;  1DII A;  5AE2 A;  3BW7 A;  3D2H A;  2P13 A;  2P4P A;  1JRO A;  1ZXI C;  4PVE A;  1SB3 B;  3RJA A;  5D79 A;  3EJE B;  2W54 A;  2W3S A;  3HRD C;  1WYG A;  2Q85 A;  1MBB A;  4JAY A;  2W3R A;  2YVS A;  1W1L A;  3EJB B;  2W55 A;  3B9J B;  5ADZ A;  2BVF A;  1V97 A;  1HSK A;  4PVK A;  1N63 C;  1UXY A;  1I19 A;  1QLU A;  3FW8 A;  4PZF A;  2O3G A;  4ML8 A;  5AE1 A;  2BVG A;  1T3Q C;  1W1O A;  3W8Z A;  3PM9 A;  3TSJ A;  5I1W A;  5FXP A;  4DNS A;  5AE3 A;  2Y3R A;  3S1C A;  5FXF A;  3FW7 A;  4BBY A;  3VTE A;  4O95 A;  3ETR B;  5L6G A;  1RM6 B;  4PWB A;  5L6F A;  1W1M A;  3W8X A;  2RK5 A;  4PYT A;  1N5X A;  1W1J A;  2VFR A;  2R2Z A;  3S1F A;  1W1Q A;  3TSH A;  3RJ8 A;  3AM9 A;  2AXR A;  1W1S A;  3POP A;  5FXD A;  1N60 C;  1N62 C;  5HQX A;  2UUU A;  2IPI A;  1E8G A;  3NVY B;  4BC9 A;  2PLS A;  1WVF A;  1E0Y A;  2GQT A;  2VFS A;  3D2D A;  2Y4G A;  2E3T A;  3FWA A;  3NVZ B;  1FIQ B;  1VAO A;  2MBR A;  1N61 C;  2BVH A;  3FW9 A;  3LAE A;  2Q4W A;  2OAI A;  1JRP A;  3NRZ B;  4PVJ A;  3EJD B;  1N5W C;  4PWC A;  2VFU A;  3D2J A;  2UUV A;  3NVV B;  3S1E A;  1AHV A;  2P3H A;  3NVW B;  2PLI A;  3DQ0 A;  4PVH A;  3DED A;  2Y08 A;  5G5G B;  1FO4 A;  2GQU A;  2R8D A;  2NQW A;  4BCA A;  3SR6 B;  1F0X A;  2VFT A;  1AHU A;  3I99 A;  1E8F A;  2EXR A;  5FXE A;  3GSY A;  4BC7 A;  4EC3 A;  1WVE A;  2QPM A;  3PQB A;  3EUB 3;  1W1R A;  1W1K A;  1QLT A;  2VFV A;  2VAO A;  1MBT A;  1DZN A;  1E8H A;  4OAL A;  3TX1 A;  3W8W A;  4HG0 A;  1DIQ A;  5G5H B;  1AHZ A;  2I0K A;  3LLB A;  5HMR A;  4ZOH B;  1FFU C;  3S1D A;  5HHZ A;  3AN1 A;  3AMZ A;  2WDW A;  3NS1 B;  2QKN A;  1VDV A;  5I1V A;  5K8E A;  2Y3S A;  1ZR6 A;  4JB1 A;  3KJM A;  4XLO A; 
#chains in the Genus database with same CATH homology
 5AWV A;  3C0P A;  1FFV C;  4MLA A;  3JS8 A;  3HSU A;  4UD8 A;  1DII A;  5AE2 A;  3BW7 A;  3D2H A;  2P13 A;  2P4P A;  1JRO A;  1ZXI C;  4PVE A;  1SB3 B;  3RJA A;  5D79 A;  2W54 A;  2W3S A;  3HRD C;  1WYG A;  2Q85 A;  1MBB A;  4JAY A;  2W3R A;  2YVS A;  1W1L A;  2W55 A;  3B9J B;  5ADZ A;  2BVF A;  1V97 A;  1HSK A;  4PVK A;  1N63 C;  1UXY A;  1I19 A;  1QLU A;  3FW8 A;  4PZF A;  2O3G A;  4ML8 A;  5AE1 A;  2BVG A;  1T3Q C;  1W1O A;  3W8Z A;  3PM9 A;  3TSJ A;  5I1W A;  5FXP A;  4DNS A;  5AE3 A;  2Y3R A;  3S1C A;  5FXF A;  3FW7 A;  4BBY A;  3VTE A;  4O95 A;  3ETR B;  5L6G A;  1RM6 B;  4PWB A;  5L6F A;  1W1M A;  3W8X A;  2RK5 A;  4PYT A;  1N5X A;  1W1J A;  2VFR A;  2R2Z A;  3S1F A;  1W1Q A;  3TSH A;  3RJ8 A;  3AM9 A;  2AXR A;  1W1S A;  3POP A;  5FXD A;  1N60 C;  1N62 C;  5HQX A;  2UUU A;  2IPI A;  1E8G A;  3NVY B;  4BC9 A;  2PLS A;  1WVF A;  1E0Y A;  2GQT A;  2VFS A;  3D2D A;  2Y4G A;  2E3T A;  3FWA A;  3NVZ B;  1FIQ B;  1VAO A;  2MBR A;  1N61 C;  2BVH A;  3FW9 A;  3LAE A;  2Q4W A;  2OAI A;  1JRP A;  3NRZ B;  4PVJ A;  1N5W C;  4PWC A;  2VFU A;  3D2J A;  2UUV A;  3NVV B;  3S1E A;  1AHV A;  2P3H A;  2PLI A;  3NVW B;  3DQ0 A;  4PVH A;  3DED A;  2Y08 A;  5G5G B;  1FO4 A;  2GQU A;  2R8D A;  2NQW A;  4BCA A;  3SR6 B;  1F0X A;  2VFT A;  1AHU A;  3I99 A;  1E8F A;  2EXR A;  5FXE A;  3GSY A;  4BC7 A;  4EC3 A;  1WVE A;  2QPM A;  3PQB A;  3EUB 3;  1W1R A;  1W1K A;  1QLT A;  2VFV A;  2VAO A;  1MBT A;  1DZN A;  1E8H A;  4OAL A;  3TX1 A;  3W8W A;  4HG0 A;  1DIQ A;  5G5H B;  1AHZ A;  2I0K A;  3LLB A;  5HMR A;  4ZOH B;  1FFU C;  3S1D A;  5HHZ A;  3AN1 A;  3AMZ A;  2WDW A;  3NS1 B;  2QKN A;  1VDV A;  5I1V A;  5K8E A;  2Y3S A;  1ZR6 A;  4JB1 A;  3KJM A;  4XLO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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