1AHVA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase in complex with 2-nitro-p-cresol
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
555
structure length
555
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISSKDQIVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
pubmed doi rcsb
molecule tags Flavoenzyme
total genus 165
structure length 555
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 1997-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1ahvA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1ahvA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1ahvA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1ahvA03
1N5WC 1N5XA 3W8ZA 1W1RA 2VFRA 5HMRA 1N63C 3S1FA 1FO4A 1RM6B 2W54A 4PVEA 3KJMA 2QKNA 1VAOA 2W55A 2VAOA 5FXPA 2GQTA 2PLIA 3FW8A 5HHZA 3DQ0A 4O95A 1AHVA 4JAYA 5FXFA 1W1JA 1QLUA 3TX1A 1DIIA 2W3RA 1V97A 4UD8A 3D2JA 1MBTA 4PVJA 4HG0A 3EUB3 5FXDA 5HQXA 1SB3B 1N62C 3S1CA 3NVZB 3NVVB 2BVFA 2VFUA 4ML8A 3D2DA 1E8GA 1FFUC 3SR6B 5AE2A 3S1DA 1HSKA 1QLTA 2P4PA 2EXRA 2YVSA 3TSHA 3C0PA 1FIQB 2GQUA 3AM9A 1AHUA 2VFTA 1WVEA 1N61C 4XLOA 3AMZA 3NVYB 5ADZA 1FFVC 2BVGA 3FW9A 4DNSA 3VTEA 5D79A 4BC7A 4PWBA 3HRDC 1JRPA 3W8WA 1AHZA 3NVWB 4PWCA 2AXRA 3S1EA 3GSYA 3I99A 1ZR6A 3PM9A 2MBRA 3FWAA 5AE3A 1F0XA 3JS8A 1UXYA 1W1SA 1W1QA 2P13A 5G5GB 1E8HA 3NRZB 3ETRB 3DEDA 2Q85A 4PVHA 4ZOHB 4PYTA 3AN1A 3TSJA 4JB1A 3B9JB 1DIQA 2VFSA 5AE1A 3NS1B 4OALA 3LAEA 1ZXIC 3LLBA 5G5HB 3W8XA 3D2HA 1T3QC 5FXEA 2W3SA 4BCAA 1W1MA 4MLAA 2R8DA 1WYGA 2P3HA 1I19A 4BBYA 2BVHA 4EC3A 2E3TA 1JROA 1DZNA 2O3GA 4PVKA 3BW7A 2OAIA 4BC9A 1E8FA 2PLSA 1W1OA 2QPMA 3FW7A 1WVFA 1VDVA 2I0KA 1MBBA 1W1KA 4PZFA 2R2ZA 2RK5A 2VFVA 1N60C 1E0YA 2Q4WA 2NQWA 1W1LA
chains in the Genus database with same CATH superfamily
1N5WC 1N5XA 3W8ZA 2UUVA 1W1RA 2VFRA 5HMRA 1N63C 3S1FA 3RJ8A 1FO4A 1RM6B 2W54A 4PVEA 3KJMA 2QKNA 1VAOA 2W55A 2VAOA 5AWVA 5FXPA 2GQTA 2PLIA 3FW8A 5HHZA 3DQ0A 4O95A 1AHVA 4JAYA 5FXFA 1W1JA 1QLUA 3TX1A 1DIIA 2W3RA 2Y3SA 1V97A 4UD8A 3D2JA 1MBTA 4PVJA 4HG0A 3EUB3 5FXDA 5HQXA 1SB3B 1N62C 3S1CA 3NVZB 3NVVB 2BVFA 2VFUA 4ML8A 5L6GA 3D2DA 1E8GA 1FFUC 2Y3RA 3SR6B 5AE2A 3S1DA 1HSKA 1QLTA 3EJBB 2P4PA 2WDWA 2EXRA 5L6FA 3PQBA 2YVSA 3TSHA 3C0PA 1FIQB 2GQUA 3AM9A 1AHUA 2VFTA 1WVEA 1N61C 3EJDB 4XLOA 3AMZA 3NVYB 5ADZA 1FFVC 2BVGA 2IPIA 3FW9A 4DNSA 3VTEA 5D79A 4BC7A 4PWBA 3HRDC 1JRPA 3W8WA 1AHZA 3NVWB 4PWCA 2AXRA 2Y08A 3S1EA 3GSYA 3I99A 1ZR6A 3PM9A 2MBRA 3FWAA 5AE3A 1F0XA 3JS8A 1UXYA 1W1SA 1W1QA 2P13A 2UUUA 1E8HA 3NRZB 5G5GB 3ETRB 3DEDA 5I1WA 2Q85A 3EJEB 4PVHA 4ZOHB 4PYTA 3AN1A 5K8EA 3TSJA 4JB1A 3B9JB 1DIQA 3RJAA 2VFSA 5AE1A 3NS1B 4OALA 3LAEA 1ZXIC 3LLBA 3POPA 5G5HB 3W8XA 3D2HA 1T3QC 5FXEA 2W3SA 4BCAA 1W1MA 4MLAA 2R8DA 1WYGA 2P3HA 2Y4GA 3HSUA 1I19A 4BBYA 2BVHA 4EC3A 2E3TA 1JROA 1DZNA 2O3GA 4PVKA 3BW7A 5I1VA 2OAIA 4BC9A 1E8FA 2PLSA 1W1OA 2QPMA 3FW7A 1WVFA 1VDVA 2I0KA 1MBBA 1W1KA 4PZFA 2R2ZA 2RK5A 2VFVA 1N60C 1E0YA 2Q4WA 2NQWA 1W1LA
chains in the Genus database with same CATH topology
1N5WC 1N5XA 3W8ZA 2UUVA 1W1RA 2VFRA 5HMRA 1N63C 3S1FA 3RJ8A 1FO4A 1RM6B 2W54A 4PVEA 3KJMA 2QKNA 1VAOA 2W55A 2VAOA 5AWVA 5FXPA 2GQTA 2PLIA 3FW8A 5HHZA 3DQ0A 4O95A 1AHVA 4JAYA 5FXFA 1W1JA 1QLUA 3TX1A 1DIIA 2W3RA 2Y3SA 1V97A 4UD8A 3D2JA 1MBTA 4PVJA 4HG0A 3EUB3 5FXDA 5HQXA 1SB3B 1N62C 3S1CA 3NVZB 3NVVB 2BVFA 2VFUA 4ML8A 5L6GA 3D2DA 1E8GA 1FFUC 2Y3RA 3SR6B 5AE2A 3S1DA 1HSKA 1QLTA 2P4PA 2WDWA 2EXRA 5L6FA 3PQBA 2YVSA 3TSHA 3C0PA 1FIQB 2GQUA 3AM9A 1AHUA 2VFTA 1WVEA 1N61C 4XLOA 3AMZA 3NVYB 5ADZA 1FFVC 2BVGA 2IPIA 3FW9A 4DNSA 3VTEA 5D79A 4BC7A 4PWBA 3HRDC 1JRPA 3W8WA 1AHZA 2Y08A 4PWCA 2AXRA 3NVWB 3S1EA 3GSYA 3I99A 1ZR6A 3PM9A 2MBRA 3FWAA 5AE3A 1F0XA 3JS8A 1UXYA 1W1SA 1W1QA 2P13A 2UUUA 1E8HA 3NRZB 5G5GB 3ETRB 3DEDA 5I1WA 2Q85A 4PVHA 4ZOHB 4PYTA 3AN1A 5K8EA 3TSJA 4JB1A 3B9JB 1DIQA 3RJAA 2VFSA 5AE1A 3NS1B 4OALA 3LAEA 1ZXIC 3LLBA 3POPA 5G5HB 3W8XA 3D2HA 1T3QC 5FXEA 2W3SA 4BCAA 1W1MA 4MLAA 2R8DA 1WYGA 2P3HA 2Y4GA 3HSUA 1I19A 4BBYA 2BVHA 4EC3A 2E3TA 1JROA 1DZNA 2O3GA 4PVKA 3BW7A 5I1VA 2OAIA 4BC9A 1E8FA 2PLSA 1W1OA 2QPMA 3FW7A 1WVFA 1VDVA 2I0KA 1MBBA 1W1KA 4PZFA 2R2ZA 2RK5A 2VFVA 1N60C 1E0YA 2Q4WA 2NQWA 1W1LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N5W C;  1N5X A;  3W8Z A;  1W1R A;  2VFR A;  5HMR A;  1N63 C;  3S1F A;  1FO4 A;  1RM6 B;  2W54 A;  4PVE A;  3KJM A;  2QKN A;  1VAO A;  2W55 A;  2VAO A;  5FXP A;  2GQT A;  2PLI A;  3FW8 A;  5HHZ A;  3DQ0 A;  4O95 A;  1AHV A;  4JAY A;  5FXF A;  1W1J A;  1QLU A;  3TX1 A;  1DII A;  2W3R A;  1V97 A;  4UD8 A;  3D2J A;  1MBT A;  4PVJ A;  4HG0 A;  3EUB 3;  5FXD A;  5HQX A;  1SB3 B;  1N62 C;  3S1C A;  3NVZ B;  3NVV B;  2BVF A;  2VFU A;  4ML8 A;  3D2D A;  1E8G A;  1FFU C;  3SR6 B;  5AE2 A;  3S1D A;  1HSK A;  1QLT A;  2P4P A;  2EXR A;  2YVS A;  3TSH A;  3C0P A;  1FIQ B;  2GQU A;  3AM9 A;  1AHU A;  2VFT A;  1WVE A;  1N61 C;  4XLO A;  3AMZ A;  3NVY B;  5ADZ A;  1FFV C;  2BVG A;  3FW9 A;  4DNS A;  3VTE A;  5D79 A;  4BC7 A;  4PWB A;  3HRD C;  1JRP A;  3W8W A;  1AHZ A;  3NVW B;  4PWC A;  2AXR A;  3S1E A;  3GSY A;  3I99 A;  1ZR6 A;  3PM9 A;  2MBR A;  3FWA A;  5AE3 A;  1F0X A;  3JS8 A;  1UXY A;  1W1S A;  1W1Q A;  2P13 A;  5G5G B;  1E8H A;  3NRZ B;  3ETR B;  3DED A;  2Q85 A;  4PVH A;  4ZOH B;  4PYT A;  3AN1 A;  3TSJ A;  4JB1 A;  3B9J B;  1DIQ A;  2VFS A;  5AE1 A;  3NS1 B;  4OAL A;  3LAE A;  1ZXI C;  3LLB A;  5G5H B;  3W8X A;  3D2H A;  1T3Q C;  5FXE A;  2W3S A;  4BCA A;  1W1M A;  4MLA A;  2R8D A;  1WYG A;  2P3H A;  1I19 A;  4BBY A;  2BVH A;  4EC3 A;  2E3T A;  1JRO A;  1DZN A;  2O3G A;  4PVK A;  3BW7 A;  2OAI A;  4BC9 A;  1E8F A;  2PLS A;  1W1O A;  2QPM A;  3FW7 A;  1WVF A;  1VDV A;  2I0K A;  1MBB A;  1W1K A;  4PZF A;  2R2Z A;  2RK5 A;  2VFV A;  1N60 C;  1E0Y A;  2Q4W A;  2NQW A;  1W1L A; 
#chains in the Genus database with same CATH topology
 1N5W C;  1N5X A;  3W8Z A;  2UUV A;  1W1R A;  2VFR A;  5HMR A;  1N63 C;  3S1F A;  3RJ8 A;  1FO4 A;  1RM6 B;  2W54 A;  4PVE A;  3KJM A;  2QKN A;  1VAO A;  2W55 A;  2VAO A;  5AWV A;  5FXP A;  2GQT A;  2PLI A;  3FW8 A;  5HHZ A;  3DQ0 A;  4O95 A;  1AHV A;  4JAY A;  5FXF A;  1W1J A;  1QLU A;  3TX1 A;  1DII A;  2W3R A;  2Y3S A;  1V97 A;  4UD8 A;  3D2J A;  1MBT A;  4PVJ A;  4HG0 A;  3EUB 3;  5FXD A;  5HQX A;  1SB3 B;  1N62 C;  3S1C A;  3NVZ B;  3NVV B;  2BVF A;  2VFU A;  4ML8 A;  5L6G A;  3D2D A;  1E8G A;  1FFU C;  2Y3R A;  3SR6 B;  5AE2 A;  3S1D A;  1HSK A;  1QLT A;  3EJB B;  2P4P A;  2WDW A;  2EXR A;  5L6F A;  3PQB A;  2YVS A;  3TSH A;  3C0P A;  1FIQ B;  2GQU A;  3AM9 A;  1AHU A;  2VFT A;  1WVE A;  1N61 C;  3EJD B;  4XLO A;  3AMZ A;  3NVY B;  5ADZ A;  1FFV C;  2BVG A;  2IPI A;  3FW9 A;  4DNS A;  3VTE A;  5D79 A;  4BC7 A;  4PWB A;  3HRD C;  1JRP A;  3W8W A;  1AHZ A;  3NVW B;  4PWC A;  2AXR A;  2Y08 A;  3S1E A;  3GSY A;  3I99 A;  1ZR6 A;  3PM9 A;  2MBR A;  3FWA A;  5AE3 A;  1F0X A;  3JS8 A;  1UXY A;  1W1S A;  1W1Q A;  2P13 A;  2UUU A;  1E8H A;  3NRZ B;  5G5G B;  3ETR B;  3DED A;  5I1W A;  2Q85 A;  3EJE B;  4PVH A;  4ZOH B;  4PYT A;  3AN1 A;  5K8E A;  3TSJ A;  4JB1 A;  3B9J B;  1DIQ A;  3RJA A;  2VFS A;  5AE1 A;  3NS1 B;  4OAL A;  3LAE A;  1ZXI C;  3LLB A;  3POP A;  5G5H B;  3W8X A;  3D2H A;  1T3Q C;  5FXE A;  2W3S A;  4BCA A;  1W1M A;  4MLA A;  2R8D A;  1WYG A;  2P3H A;  2Y4G A;  3HSU A;  1I19 A;  4BBY A;  2BVH A;  4EC3 A;  2E3T A;  1JRO A;  1DZN A;  2O3G A;  4PVK A;  3BW7 A;  5I1V A;  2OAI A;  4BC9 A;  1E8F A;  2PLS A;  1W1O A;  2QPM A;  3FW7 A;  1WVF A;  1VDV A;  2I0K A;  1MBB A;  1W1K A;  4PZF A;  2R2Z A;  2RK5 A;  2VFV A;  1N60 C;  1E0Y A;  2Q4W A;  2NQW A;  1W1L A; 
#chains in the Genus database with same CATH homology
 1N5W C;  1N5X A;  3W8Z A;  2UUV A;  1W1R A;  2VFR A;  5HMR A;  1N63 C;  3S1F A;  3RJ8 A;  1FO4 A;  1RM6 B;  2W54 A;  4PVE A;  3KJM A;  2QKN A;  1VAO A;  2W55 A;  2VAO A;  5AWV A;  5FXP A;  2GQT A;  2PLI A;  3FW8 A;  5HHZ A;  3DQ0 A;  4O95 A;  1AHV A;  4JAY A;  5FXF A;  1W1J A;  1QLU A;  3TX1 A;  1DII A;  2W3R A;  2Y3S A;  1V97 A;  4UD8 A;  3D2J A;  1MBT A;  4PVJ A;  4HG0 A;  3EUB 3;  5FXD A;  5HQX A;  1SB3 B;  1N62 C;  3S1C A;  3NVZ B;  3NVV B;  2BVF A;  2VFU A;  4ML8 A;  5L6G A;  3D2D A;  1E8G A;  1FFU C;  2Y3R A;  3SR6 B;  5AE2 A;  3S1D A;  1HSK A;  1QLT A;  2P4P A;  2WDW A;  2EXR A;  5L6F A;  3PQB A;  2YVS A;  3TSH A;  3C0P A;  1FIQ B;  2GQU A;  3AM9 A;  1AHU A;  2VFT A;  1WVE A;  1N61 C;  4XLO A;  3AMZ A;  3NVY B;  5ADZ A;  1FFV C;  2BVG A;  2IPI A;  3FW9 A;  4DNS A;  3VTE A;  5D79 A;  4BC7 A;  4PWB A;  3HRD C;  1JRP A;  3W8W A;  1AHZ A;  2Y08 A;  4PWC A;  2AXR A;  3NVW B;  3S1E A;  3GSY A;  3I99 A;  1ZR6 A;  3PM9 A;  2MBR A;  3FWA A;  5AE3 A;  1F0X A;  3JS8 A;  1UXY A;  1W1S A;  1W1Q A;  2P13 A;  2UUU A;  1E8H A;  3NRZ B;  5G5G B;  3ETR B;  3DED A;  5I1W A;  2Q85 A;  4PVH A;  4ZOH B;  4PYT A;  3AN1 A;  5K8E A;  3TSJ A;  4JB1 A;  3B9J B;  1DIQ A;  3RJA A;  2VFS A;  5AE1 A;  3NS1 B;  4OAL A;  3LAE A;  1ZXI C;  3LLB A;  3POP A;  5G5H B;  3W8X A;  3D2H A;  1T3Q C;  5FXE A;  2W3S A;  4BCA A;  1W1M A;  4MLA A;  2R8D A;  1WYG A;  2P3H A;  2Y4G A;  3HSU A;  1I19 A;  4BBY A;  2BVH A;  4EC3 A;  2E3T A;  1JRO A;  1DZN A;  2O3G A;  4PVK A;  3BW7 A;  5I1V A;  2OAI A;  4BC9 A;  1E8F A;  2PLS A;  1W1O A;  2QPM A;  3FW7 A;  1WVF A;  1VDV A;  2I0K A;  1MBB A;  1W1K A;  4PZF A;  2R2Z A;  2RK5 A;  2VFV A;  1N60 C;  1E0Y A;  2Q4W A;  2NQW A;  1W1L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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