1AHVA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase in complex with 2-nitro-p-cresol
Total Genus 165
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
555
structure length
555
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISSKDQIVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
pubmed doi rcsb
molecule tags Flavoenzyme
total genus 165
structure length 555
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 1997-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1ahvA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1ahvA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1ahvA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1ahvA03
2RK5A 1AHZA 2VFVA 5AE3A 2VFRA 1FFVC 3S1CA 1MBBA 2P13A 3TSJA 3B9JB 3BW7A 5G5GB 2NQWA 1WVFA 3W8WA 4BC9A 3AN1A 3FW9A 2Q4WA 4ML8A 5AE1A 1W1OA 3W8ZA 3NVYB 1V97A 1N61C 1DIQA 3TSHA 1FO4A 1SB3B 3S1EA 2VFTA 4PVJA 2OAIA 3D2JA 3S1FA 3EUB3 4DNSA 1N62C 3SR6B 1JROA 2GQUA 2R8DA 3KJMA 2PLSA 3NRZB 4EC3A 2QKNA 4BC7A 2BVHA 5HQXA 2R2ZA 4PVEA 1ZR6A 1N5XA 1I19A 3DEDA 2VAOA 2P4PA 2VFUA 5FXFA 4BBYA 1N60C 3AM9A 3FW7A 4PWCA 5D79A 2W3SA 1DZNA 1QLTA 3FWAA 3D2DA 1ZXIC 2QPMA 1W1RA 1FFUC 1W1SA 3LAEA 3W8XA 5FXDA 3TX1A 5FXEA 4MLAA 4UD8A 1VAOA 1N63C 3FW8A 5HMRA 3NVWB 1WVEA 1F0XA 1RM6B 1W1JA 2W55A 5AE2A 3D2HA 1T3QC 1W1MA 5ADZA 5G5HB 2VFSA 2MBRA 2BVGA 1MBTA 3S1DA 1JRPA 1HSKA 2W54A 2O3GA 4ZOHB 2EXRA 3HRDC 1WYGA 4PYTA 4HG0A 3NVZB 3C0PA 4XLOA 2YVSA 3LLBA 1W1QA 2BVFA 1AHUA 2PLIA 1E8FA 1W1KA 4JB1A 4JAYA 1E8GA 5FXPA 3NVVB 1FIQB 4PZFA 3NS1B 3PM9A 3ETRB 3I99A 1UXYA 4PVHA 3VTEA 2W3RA 1E0YA 1QLUA 1W1LA 3GSYA 2I0KA 4OALA 1E8HA 4PVKA 2E3TA 4BCAA 1N5WC 3AMZA 3JS8A 2P3HA 2AXRA 1DIIA 3DQ0A 1AHVA 4O95A 5HHZA 4PWBA 1VDVA 2GQTA 2Q85A
chains in the Genus database with same CATH superfamily
2RK5A 1AHZA 2VFVA 3EJBB 5AE3A 2VFRA 1FFVC 3S1CA 1MBBA 2P13A 3TSJA 3B9JB 3BW7A 5G5GB 2UUUA 2NQWA 1WVFA 3W8WA 4BC9A 3AN1A 3FW9A 2Q4WA 4ML8A 5AE1A 1W1OA 3NVYB 3W8ZA 1V97A 1N61C 1DIQA 3TSHA 1FO4A 1SB3B 3S1EA 3RJAA 2VFTA 4PVJA 2OAIA 2Y3RA 3D2JA 3S1FA 3EUB3 5I1WA 4DNSA 1N62C 3SR6B 1JROA 3EJEB 2GQUA 2R8DA 3KJMA 2PLSA 3NRZB 4EC3A 5L6GA 3PQBA 2QKNA 4BC7A 2BVHA 5HQXA 2R2ZA 4PVEA 1ZR6A 1N5XA 1I19A 3DEDA 2VAOA 2P4PA 2VFUA 5FXFA 4BBYA 1N60C 3AM9A 3FW7A 4PWCA 5D79A 2IPIA 2W3SA 1DZNA 1QLTA 3POPA 3FWAA 3D2DA 1ZXIC 2QPMA 1W1RA 1FFUC 1W1SA 5AWVA 3LAEA 3W8XA 5FXDA 3TX1A 5FXEA 3NVWB 4MLAA 1VAOA 1N63C 3FW8A 4UD8A 5HMRA 1WVEA 2Y08A 1F0XA 1RM6B 1W1JA 2W55A 5AE2A 3D2HA 1T3QC 1W1MA 5ADZA 5G5HB 2VFSA 2Y3SA 2MBRA 3RJ8A 2BVGA 2WDWA 1MBTA 3S1DA 1JRPA 1HSKA 2W54A 2O3GA 4ZOHB 2EXRA 3HRDC 1WYGA 4PYTA 4HG0A 3NVZB 3C0PA 4XLOA 5I1VA 2YVSA 3LLBA 1W1QA 2BVFA 1AHUA 2PLIA 1E8FA 1W1KA 4JB1A 4JAYA 1E8GA 5FXPA 3NVVB 3EJDB 1FIQB 4PZFA 3NS1B 3PM9A 3ETRB 3I99A 1UXYA 4PVHA 3VTEA 2W3RA 1E0YA 1QLUA 1W1LA 3GSYA 2Y4GA 2UUVA 2I0KA 5L6FA 4OALA 1E8HA 4PVKA 5K8EA 2E3TA 3HSUA 4BCAA 1N5WC 3AMZA 3JS8A 2P3HA 2AXRA 1DIIA 3DQ0A 1AHVA 4O95A 5HHZA 4PWBA 1VDVA 2GQTA 2Q85A
chains in the Genus database with same CATH topology
2RK5A 1AHZA 2VFVA 5AE3A 2VFRA 1FFVC 3S1CA 1MBBA 2P13A 3TSJA 3B9JB 3BW7A 5G5GB 2UUUA 2NQWA 1WVFA 3W8WA 4BC9A 3AN1A 3FW9A 2Q4WA 4ML8A 5AE1A 1W1OA 3W8ZA 3NVYB 1V97A 1N61C 1DIQA 3TSHA 1FO4A 1SB3B 3S1EA 3RJAA 2VFTA 4PVJA 2OAIA 2Y3RA 3D2JA 3S1FA 3EUB3 5I1WA 4DNSA 1N62C 3SR6B 1JROA 2GQUA 2R8DA 3KJMA 2PLSA 3NRZB 4EC3A 5L6GA 3PQBA 2QKNA 4BC7A 2BVHA 5HQXA 2R2ZA 4PVEA 1ZR6A 1N5XA 1I19A 3DEDA 2VAOA 2P4PA 2VFUA 5FXFA 4BBYA 1N60C 3AM9A 3FW7A 4PWCA 5D79A 2IPIA 2W3SA 1DZNA 1QLTA 3POPA 3FWAA 3D2DA 1ZXIC 2QPMA 1W1RA 1FFUC 1W1SA 5AWVA 3LAEA 3W8XA 5FXDA 3TX1A 5FXEA 4MLAA 4UD8A 1VAOA 1N63C 3FW8A 5HMRA 3NVWB 1WVEA 2Y08A 1F0XA 1RM6B 1W1JA 2W55A 5AE2A 3D2HA 1T3QC 1W1MA 5ADZA 5G5HB 2VFSA 2Y3SA 2MBRA 3RJ8A 2BVGA 2WDWA 1MBTA 3S1DA 1JRPA 1HSKA 2W54A 2O3GA 4ZOHB 2EXRA 3HRDC 1WYGA 4PYTA 4HG0A 3NVZB 3C0PA 4XLOA 5I1VA 2YVSA 3LLBA 1W1QA 2BVFA 1AHUA 2PLIA 1E8FA 1W1KA 4JB1A 4JAYA 1E8GA 5FXPA 3NVVB 1FIQB 4PZFA 3NS1B 3PM9A 3ETRB 3I99A 1UXYA 4PVHA 3VTEA 2W3RA 1E0YA 1QLUA 1W1LA 3GSYA 2Y4GA 2UUVA 2I0KA 5L6FA 4OALA 1E8HA 4PVKA 5K8EA 2E3TA 3HSUA 4BCAA 1N5WC 3AMZA 3JS8A 2P3HA 2AXRA 1DIIA 3DQ0A 1AHVA 4O95A 5HHZA 4PWBA 1VDVA 2GQTA 2Q85A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RK5 A;  1AHZ A;  2VFV A;  5AE3 A;  2VFR A;  1FFV C;  3S1C A;  1MBB A;  2P13 A;  3TSJ A;  3B9J B;  3BW7 A;  5G5G B;  2NQW A;  1WVF A;  3W8W A;  4BC9 A;  3AN1 A;  3FW9 A;  2Q4W A;  4ML8 A;  5AE1 A;  1W1O A;  3W8Z A;  3NVY B;  1V97 A;  1N61 C;  1DIQ A;  3TSH A;  1FO4 A;  1SB3 B;  3S1E A;  2VFT A;  4PVJ A;  2OAI A;  3D2J A;  3S1F A;  3EUB 3;  4DNS A;  1N62 C;  3SR6 B;  1JRO A;  2GQU A;  2R8D A;  3KJM A;  2PLS A;  3NRZ B;  4EC3 A;  2QKN A;  4BC7 A;  2BVH A;  5HQX A;  2R2Z A;  4PVE A;  1ZR6 A;  1N5X A;  1I19 A;  3DED A;  2VAO A;  2P4P A;  2VFU A;  5FXF A;  4BBY A;  1N60 C;  3AM9 A;  3FW7 A;  4PWC A;  5D79 A;  2W3S A;  1DZN A;  1QLT A;  3FWA A;  3D2D A;  1ZXI C;  2QPM A;  1W1R A;  1FFU C;  1W1S A;  3LAE A;  3W8X A;  5FXD A;  3TX1 A;  5FXE A;  4MLA A;  4UD8 A;  1VAO A;  1N63 C;  3FW8 A;  5HMR A;  3NVW B;  1WVE A;  1F0X A;  1RM6 B;  1W1J A;  2W55 A;  5AE2 A;  3D2H A;  1T3Q C;  1W1M A;  5ADZ A;  5G5H B;  2VFS A;  2MBR A;  2BVG A;  1MBT A;  3S1D A;  1JRP A;  1HSK A;  2W54 A;  2O3G A;  4ZOH B;  2EXR A;  3HRD C;  1WYG A;  4PYT A;  4HG0 A;  3NVZ B;  3C0P A;  4XLO A;  2YVS A;  3LLB A;  1W1Q A;  2BVF A;  1AHU A;  2PLI A;  1E8F A;  1W1K A;  4JB1 A;  4JAY A;  1E8G A;  5FXP A;  3NVV B;  1FIQ B;  4PZF A;  3NS1 B;  3PM9 A;  3ETR B;  3I99 A;  1UXY A;  4PVH A;  3VTE A;  2W3R A;  1E0Y A;  1QLU A;  1W1L A;  3GSY A;  2I0K A;  4OAL A;  1E8H A;  4PVK A;  2E3T A;  4BCA A;  1N5W C;  3AMZ A;  3JS8 A;  2P3H A;  2AXR A;  1DII A;  3DQ0 A;  1AHV A;  4O95 A;  5HHZ A;  4PWB A;  1VDV A;  2GQT A;  2Q85 A; 
#chains in the Genus database with same CATH topology
 2RK5 A;  1AHZ A;  2VFV A;  3EJB B;  5AE3 A;  2VFR A;  1FFV C;  3S1C A;  1MBB A;  2P13 A;  3TSJ A;  3B9J B;  3BW7 A;  5G5G B;  2UUU A;  2NQW A;  1WVF A;  3W8W A;  4BC9 A;  3AN1 A;  3FW9 A;  2Q4W A;  4ML8 A;  5AE1 A;  1W1O A;  3NVY B;  3W8Z A;  1V97 A;  1N61 C;  1DIQ A;  3TSH A;  1FO4 A;  1SB3 B;  3S1E A;  3RJA A;  2VFT A;  4PVJ A;  2OAI A;  2Y3R A;  3D2J A;  3S1F A;  3EUB 3;  5I1W A;  4DNS A;  1N62 C;  3SR6 B;  1JRO A;  3EJE B;  2GQU A;  2R8D A;  3KJM A;  2PLS A;  3NRZ B;  4EC3 A;  5L6G A;  3PQB A;  2QKN A;  4BC7 A;  2BVH A;  5HQX A;  2R2Z A;  4PVE A;  1ZR6 A;  1N5X A;  1I19 A;  3DED A;  2VAO A;  2P4P A;  2VFU A;  5FXF A;  4BBY A;  1N60 C;  3AM9 A;  3FW7 A;  4PWC A;  5D79 A;  2IPI A;  2W3S A;  1DZN A;  1QLT A;  3POP A;  3FWA A;  3D2D A;  1ZXI C;  2QPM A;  1W1R A;  1FFU C;  1W1S A;  5AWV A;  3LAE A;  3W8X A;  5FXD A;  3TX1 A;  5FXE A;  3NVW B;  4MLA A;  1VAO A;  1N63 C;  3FW8 A;  4UD8 A;  5HMR A;  1WVE A;  2Y08 A;  1F0X A;  1RM6 B;  1W1J A;  2W55 A;  5AE2 A;  3D2H A;  1T3Q C;  1W1M A;  5ADZ A;  5G5H B;  2VFS A;  2Y3S A;  2MBR A;  3RJ8 A;  2BVG A;  2WDW A;  1MBT A;  3S1D A;  1JRP A;  1HSK A;  2W54 A;  2O3G A;  4ZOH B;  2EXR A;  3HRD C;  1WYG A;  4PYT A;  4HG0 A;  3NVZ B;  3C0P A;  4XLO A;  5I1V A;  2YVS A;  3LLB A;  1W1Q A;  2BVF A;  1AHU A;  2PLI A;  1E8F A;  1W1K A;  4JB1 A;  4JAY A;  1E8G A;  5FXP A;  3NVV B;  3EJD B;  1FIQ B;  4PZF A;  3NS1 B;  3PM9 A;  3ETR B;  3I99 A;  1UXY A;  4PVH A;  3VTE A;  2W3R A;  1E0Y A;  1QLU A;  1W1L A;  3GSY A;  2Y4G A;  2UUV A;  2I0K A;  5L6F A;  4OAL A;  1E8H A;  4PVK A;  5K8E A;  2E3T A;  3HSU A;  4BCA A;  1N5W C;  3AMZ A;  3JS8 A;  2P3H A;  2AXR A;  1DII A;  3DQ0 A;  1AHV A;  4O95 A;  5HHZ A;  4PWB A;  1VDV A;  2GQT A;  2Q85 A; 
#chains in the Genus database with same CATH homology
 2RK5 A;  1AHZ A;  2VFV A;  5AE3 A;  2VFR A;  1FFV C;  3S1C A;  1MBB A;  2P13 A;  3TSJ A;  3B9J B;  3BW7 A;  5G5G B;  2UUU A;  2NQW A;  1WVF A;  3W8W A;  4BC9 A;  3AN1 A;  3FW9 A;  2Q4W A;  4ML8 A;  5AE1 A;  1W1O A;  3W8Z A;  3NVY B;  1V97 A;  1N61 C;  1DIQ A;  3TSH A;  1FO4 A;  1SB3 B;  3S1E A;  3RJA A;  2VFT A;  4PVJ A;  2OAI A;  2Y3R A;  3D2J A;  3S1F A;  3EUB 3;  5I1W A;  4DNS A;  1N62 C;  3SR6 B;  1JRO A;  2GQU A;  2R8D A;  3KJM A;  2PLS A;  3NRZ B;  4EC3 A;  5L6G A;  3PQB A;  2QKN A;  4BC7 A;  2BVH A;  5HQX A;  2R2Z A;  4PVE A;  1ZR6 A;  1N5X A;  1I19 A;  3DED A;  2VAO A;  2P4P A;  2VFU A;  5FXF A;  4BBY A;  1N60 C;  3AM9 A;  3FW7 A;  4PWC A;  5D79 A;  2IPI A;  2W3S A;  1DZN A;  1QLT A;  3POP A;  3FWA A;  3D2D A;  1ZXI C;  2QPM A;  1W1R A;  1FFU C;  1W1S A;  5AWV A;  3LAE A;  3W8X A;  5FXD A;  3TX1 A;  5FXE A;  4MLA A;  4UD8 A;  1VAO A;  1N63 C;  3FW8 A;  5HMR A;  3NVW B;  1WVE A;  2Y08 A;  1F0X A;  1RM6 B;  1W1J A;  2W55 A;  5AE2 A;  3D2H A;  1T3Q C;  1W1M A;  5ADZ A;  5G5H B;  2VFS A;  2Y3S A;  2MBR A;  3RJ8 A;  2BVG A;  2WDW A;  1MBT A;  3S1D A;  1JRP A;  1HSK A;  2W54 A;  2O3G A;  4ZOH B;  2EXR A;  3HRD C;  1WYG A;  4PYT A;  4HG0 A;  3NVZ B;  3C0P A;  4XLO A;  5I1V A;  2YVS A;  3LLB A;  1W1Q A;  2BVF A;  1AHU A;  2PLI A;  1E8F A;  1W1K A;  4JB1 A;  4JAY A;  1E8G A;  5FXP A;  3NVV B;  1FIQ B;  4PZF A;  3NS1 B;  3PM9 A;  3ETR B;  3I99 A;  1UXY A;  4PVH A;  3VTE A;  2W3R A;  1E0Y A;  1QLU A;  1W1L A;  3GSY A;  2Y4G A;  2UUV A;  2I0K A;  5L6F A;  4OAL A;  1E8H A;  4PVK A;  5K8E A;  2E3T A;  3HSU A;  4BCA A;  1N5W C;  3AMZ A;  3JS8 A;  2P3H A;  2AXR A;  1DII A;  3DQ0 A;  1AHV A;  4O95 A;  5HHZ A;  4PWB A;  1VDV A;  2GQT A;  2Q85 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...