1AHVA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase in complex with 2-nitro-p-cresol
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
555
structure length
555
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISSKDQIVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
pubmed doi rcsb
molecule tags Flavoenzyme
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 165
structure length 555
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 1997-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1ahvA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1ahvA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1ahvA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1ahvA03
3B9JB 3I99A 2P3HA 1E8GA 2BVGA 2W54A 3D2HA 1W1LA 2W3RA 4ML8A 3S1FA 5FXEA 1AHVA 3DEDA 3D2DA 3BW7A 3NRZB 4PYTA 2Q85A 3W8ZA 2BVHA 2O3GA 1WVEA 3PM9A 4PVKA 2VFVA 3W8WA 3W8XA 1QLTA 1JROA 4O95A 3S1CA 4PZFA 2W3SA 4PWCA 3AMZA 5AE2A 1MBTA 3NVZB 1SB3B 3DQ0A 2GQUA 4PVEA 1N63C 3VTEA 1VAOA 1N60C 1WVFA 2VFSA 4PVHA 2NQWA 1ZR6A 2I0KA 1W1KA 1N5WC 1W1OA 1N62C 5FXFA 1I19A 5ADZA 3LLBA 4BCAA 3GSYA 1W1QA 4ZOHB 3AN1A 4BBYA 1JRPA 1N5XA 1E8HA 5HQXA 3NS1B 1N61C 3D2JA 2YVSA 1W1MA 5D79A 1HSKA 3NVVB 5FXPA 1FO4A 2W55A 4DNSA 3AM9A 3TSJA 1DZNA 1AHZA 2E3TA 1WYGA 2BVFA 2R2ZA 2RK5A 2VFTA 4BC7A 1DIIA 2EXRA 3SR6B 3ETRB 3TSHA 4JAYA 2PLSA 4EC3A 2QPMA 1MBBA 3FW8A 2PLIA 3S1DA 2QKNA 3NVWB 1E0YA 2Q4WA 4MLAA 1FFUC 4XLOA 2VAOA 4HG0A 3FW9A 2OAIA 3EUB3 3FWAA 1ZXIC 5HHZA 4PWBA 2P13A 1E8FA 4JB1A 1T3QC 4UD8A 2AXRA 1W1SA 2GQTA 4BC9A 3JS8A 1DIQA 1FIQB 3LAEA 2R8DA 5G5GB 2P4PA 1AHUA 5AE1A 2VFUA 2VFRA 3KJMA 3HRDC 1FFVC 5G5HB 1QLUA 3FW7A 5HMRA 5AE3A 2MBRA 1F0XA 3NVYB 4OALA 5FXDA 1UXYA 4PVJA 1VDVA 1W1RA 3C0PA 3S1EA 1RM6B 3TX1A 1V97A 1W1JA
chains in the Genus database with same CATH superfamily
3B9JB 3I99A 2P3HA 1E8GA 2BVGA 2W54A 3D2HA 3POPA 1W1LA 2WDWA 5I1WA 3EJEB 2W3RA 2Y4GA 4ML8A 5K8EA 3S1FA 5FXEA 1AHVA 3EJBB 3DEDA 3D2DA 3BW7A 3NRZB 4PYTA 2Q85A 3W8ZA 2BVHA 2O3GA 1WVEA 3PM9A 4PVKA 2VFVA 3W8WA 3W8XA 1QLTA 1JROA 4O95A 5L6GA 3S1CA 4PZFA 2W3SA 4PWCA 3AMZA 5AE2A 1MBTA 3NVZB 1SB3B 3DQ0A 2GQUA 4PVEA 1N63C 3VTEA 1VAOA 1N60C 1WVFA 2VFSA 4PVHA 2NQWA 2Y3RA 1ZR6A 2I0KA 1W1KA 1N5WC 1W1OA 1N62C 5FXFA 1I19A 5ADZA 3LLBA 4BCAA 3GSYA 1W1QA 4ZOHB 3AN1A 4BBYA 1JRPA 2UUUA 1N5XA 1E8HA 5HQXA 3NS1B 1N61C 3D2JA 2YVSA 1W1MA 5D79A 1HSKA 3NVVB 5FXPA 1FO4A 2W55A 4DNSA 3PQBA 3AM9A 3TSJA 1DZNA 1AHZA 3RJ8A 2E3TA 1WYGA 2BVFA 2UUVA 2R2ZA 2RK5A 2VFTA 4BC7A 1DIIA 2EXRA 3SR6B 3EJDB 3ETRB 3TSHA 4JAYA 2PLSA 4EC3A 2QPMA 1MBBA 3FW8A 2PLIA 3S1DA 2QKNA 3NVWB 2Y3SA 1E0YA 2Q4WA 4MLAA 1FFUC 3RJAA 4XLOA 5AWVA 2VAOA 4HG0A 5I1VA 3FW9A 2OAIA 3EUB3 3FWAA 1ZXIC 5HHZA 4PWBA 2P13A 1E8FA 4JB1A 1T3QC 2Y08A 4UD8A 2AXRA 1W1SA 2GQTA 4BC9A 3JS8A 1DIQA 1FIQB 3LAEA 2R8DA 5G5GB 2IPIA 2P4PA 1AHUA 5AE1A 2VFUA 2VFRA 3KJMA 3HRDC 1FFVC 5G5HB 1QLUA 3FW7A 5HMRA 5AE3A 2MBRA 1F0XA 3NVYB 5L6FA 4OALA 5FXDA 1UXYA 4PVJA 1VDVA 1W1RA 3C0PA 3S1EA 3HSUA 1RM6B 3TX1A 1V97A 1W1JA
chains in the Genus database with same CATH topology
3B9JB 3I99A 2P3HA 1E8GA 2BVGA 2W54A 3D2HA 3POPA 1W1LA 2WDWA 5I1WA 2W3RA 2Y4GA 4ML8A 5K8EA 3S1FA 5FXEA 1AHVA 3DEDA 3D2DA 3BW7A 3NRZB 4PYTA 2Q85A 3W8ZA 2BVHA 2O3GA 1WVEA 3PM9A 4PVKA 2VFVA 3W8WA 3W8XA 1QLTA 1JROA 4O95A 5L6GA 3S1CA 4PZFA 2W3SA 4PWCA 3AMZA 5AE2A 1MBTA 3NVZB 1SB3B 3DQ0A 2GQUA 4PVEA 1N63C 3VTEA 1VAOA 1N60C 1WVFA 2VFSA 4PVHA 2NQWA 2Y3RA 1ZR6A 2I0KA 1W1KA 1N5WC 1W1OA 1N62C 5FXFA 1I19A 5ADZA 3LLBA 4BCAA 3GSYA 1W1QA 4ZOHB 3AN1A 4BBYA 1JRPA 2UUUA 1N5XA 1E8HA 5HQXA 3NS1B 1N61C 3D2JA 2YVSA 1W1MA 5D79A 1HSKA 3NVVB 5FXPA 1FO4A 2W55A 4DNSA 3PQBA 3AM9A 3TSJA 1DZNA 1AHZA 3RJ8A 2E3TA 1WYGA 2BVFA 2UUVA 2R2ZA 2RK5A 2VFTA 4BC7A 1DIIA 2EXRA 3SR6B 3ETRB 3TSHA 4JAYA 2PLSA 4EC3A 2QPMA 1MBBA 3FW8A 2PLIA 3S1DA 2QKNA 2Y3SA 3NVWB 1E0YA 2Q4WA 4MLAA 1FFUC 3RJAA 4XLOA 5AWVA 2VAOA 4HG0A 5I1VA 3FW9A 2OAIA 3EUB3 3FWAA 1ZXIC 5HHZA 4PWBA 2P13A 1E8FA 4JB1A 1T3QC 2Y08A 4UD8A 2AXRA 1W1SA 2GQTA 4BC9A 3JS8A 1DIQA 1FIQB 3LAEA 2R8DA 5G5GB 2IPIA 2P4PA 1AHUA 5AE1A 2VFUA 2VFRA 3KJMA 3HRDC 1FFVC 5G5HB 1QLUA 3FW7A 5HMRA 5AE3A 2MBRA 1F0XA 3NVYB 5L6FA 4OALA 5FXDA 1UXYA 4PVJA 1VDVA 1W1RA 3C0PA 3S1EA 3HSUA 1RM6B 3TX1A 1V97A 1W1JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3B9J B;  3I99 A;  2P3H A;  1E8G A;  2BVG A;  2W54 A;  3D2H A;  1W1L A;  2W3R A;  4ML8 A;  3S1F A;  5FXE A;  1AHV A;  3DED A;  3D2D A;  3BW7 A;  3NRZ B;  4PYT A;  2Q85 A;  3W8Z A;  2BVH A;  2O3G A;  1WVE A;  3PM9 A;  4PVK A;  2VFV A;  3W8W A;  3W8X A;  1QLT A;  1JRO A;  4O95 A;  3S1C A;  4PZF A;  2W3S A;  4PWC A;  3AMZ A;  5AE2 A;  1MBT A;  3NVZ B;  1SB3 B;  3DQ0 A;  2GQU A;  4PVE A;  1N63 C;  3VTE A;  1VAO A;  1N60 C;  1WVF A;  2VFS A;  4PVH A;  2NQW A;  1ZR6 A;  2I0K A;  1W1K A;  1N5W C;  1W1O A;  1N62 C;  5FXF A;  1I19 A;  5ADZ A;  3LLB A;  4BCA A;  3GSY A;  1W1Q A;  4ZOH B;  3AN1 A;  4BBY A;  1JRP A;  1N5X A;  1E8H A;  5HQX A;  3NS1 B;  1N61 C;  3D2J A;  2YVS A;  1W1M A;  5D79 A;  1HSK A;  3NVV B;  5FXP A;  1FO4 A;  2W55 A;  4DNS A;  3AM9 A;  3TSJ A;  1DZN A;  1AHZ A;  2E3T A;  1WYG A;  2BVF A;  2R2Z A;  2RK5 A;  2VFT A;  4BC7 A;  1DII A;  2EXR A;  3SR6 B;  3ETR B;  3TSH A;  4JAY A;  2PLS A;  4EC3 A;  2QPM A;  1MBB A;  3FW8 A;  2PLI A;  3S1D A;  2QKN A;  3NVW B;  1E0Y A;  2Q4W A;  4MLA A;  1FFU C;  4XLO A;  2VAO A;  4HG0 A;  3FW9 A;  2OAI A;  3EUB 3;  3FWA A;  1ZXI C;  5HHZ A;  4PWB A;  2P13 A;  1E8F A;  4JB1 A;  1T3Q C;  4UD8 A;  2AXR A;  1W1S A;  2GQT A;  4BC9 A;  3JS8 A;  1DIQ A;  1FIQ B;  3LAE A;  2R8D A;  5G5G B;  2P4P A;  1AHU A;  5AE1 A;  2VFU A;  2VFR A;  3KJM A;  3HRD C;  1FFV C;  5G5H B;  1QLU A;  3FW7 A;  5HMR A;  5AE3 A;  2MBR A;  1F0X A;  3NVY B;  4OAL A;  5FXD A;  1UXY A;  4PVJ A;  1VDV A;  1W1R A;  3C0P A;  3S1E A;  1RM6 B;  3TX1 A;  1V97 A;  1W1J A; 
#chains in the Genus database with same CATH topology
 3B9J B;  3I99 A;  2P3H A;  1E8G A;  2BVG A;  2W54 A;  3D2H A;  3POP A;  1W1L A;  2WDW A;  5I1W A;  3EJE B;  2W3R A;  2Y4G A;  4ML8 A;  5K8E A;  3S1F A;  5FXE A;  1AHV A;  3EJB B;  3DED A;  3D2D A;  3BW7 A;  3NRZ B;  4PYT A;  2Q85 A;  3W8Z A;  2BVH A;  2O3G A;  1WVE A;  3PM9 A;  4PVK A;  2VFV A;  3W8W A;  3W8X A;  1QLT A;  1JRO A;  4O95 A;  5L6G A;  3S1C A;  4PZF A;  2W3S A;  4PWC A;  3AMZ A;  5AE2 A;  1MBT A;  3NVZ B;  1SB3 B;  3DQ0 A;  2GQU A;  4PVE A;  1N63 C;  3VTE A;  1VAO A;  1N60 C;  1WVF A;  2VFS A;  4PVH A;  2NQW A;  2Y3R A;  1ZR6 A;  2I0K A;  1W1K A;  1N5W C;  1W1O A;  1N62 C;  5FXF A;  1I19 A;  5ADZ A;  3LLB A;  4BCA A;  3GSY A;  1W1Q A;  4ZOH B;  3AN1 A;  4BBY A;  1JRP A;  2UUU A;  1N5X A;  1E8H A;  5HQX A;  3NS1 B;  1N61 C;  3D2J A;  2YVS A;  1W1M A;  5D79 A;  1HSK A;  3NVV B;  5FXP A;  1FO4 A;  2W55 A;  4DNS A;  3PQB A;  3AM9 A;  3TSJ A;  1DZN A;  1AHZ A;  3RJ8 A;  2E3T A;  1WYG A;  2BVF A;  2UUV A;  2R2Z A;  2RK5 A;  2VFT A;  4BC7 A;  1DII A;  2EXR A;  3SR6 B;  3EJD B;  3ETR B;  3TSH A;  4JAY A;  2PLS A;  4EC3 A;  2QPM A;  1MBB A;  3FW8 A;  2PLI A;  3S1D A;  2QKN A;  3NVW B;  2Y3S A;  1E0Y A;  2Q4W A;  4MLA A;  1FFU C;  3RJA A;  4XLO A;  5AWV A;  2VAO A;  4HG0 A;  5I1V A;  3FW9 A;  2OAI A;  3EUB 3;  3FWA A;  1ZXI C;  5HHZ A;  4PWB A;  2P13 A;  1E8F A;  4JB1 A;  1T3Q C;  2Y08 A;  4UD8 A;  2AXR A;  1W1S A;  2GQT A;  4BC9 A;  3JS8 A;  1DIQ A;  1FIQ B;  3LAE A;  2R8D A;  5G5G B;  2IPI A;  2P4P A;  1AHU A;  5AE1 A;  2VFU A;  2VFR A;  3KJM A;  3HRD C;  1FFV C;  5G5H B;  1QLU A;  3FW7 A;  5HMR A;  5AE3 A;  2MBR A;  1F0X A;  3NVY B;  5L6F A;  4OAL A;  5FXD A;  1UXY A;  4PVJ A;  1VDV A;  1W1R A;  3C0P A;  3S1E A;  3HSU A;  1RM6 B;  3TX1 A;  1V97 A;  1W1J A; 
#chains in the Genus database with same CATH homology
 3B9J B;  3I99 A;  2P3H A;  1E8G A;  2BVG A;  2W54 A;  3D2H A;  3POP A;  1W1L A;  2WDW A;  5I1W A;  2W3R A;  2Y4G A;  4ML8 A;  5K8E A;  3S1F A;  5FXE A;  1AHV A;  3DED A;  3D2D A;  3BW7 A;  3NRZ B;  4PYT A;  2Q85 A;  3W8Z A;  2BVH A;  2O3G A;  1WVE A;  3PM9 A;  4PVK A;  2VFV A;  3W8W A;  3W8X A;  1QLT A;  1JRO A;  4O95 A;  5L6G A;  3S1C A;  4PZF A;  2W3S A;  4PWC A;  3AMZ A;  5AE2 A;  1MBT A;  3NVZ B;  1SB3 B;  3DQ0 A;  2GQU A;  4PVE A;  1N63 C;  3VTE A;  1VAO A;  1N60 C;  1WVF A;  2VFS A;  4PVH A;  2NQW A;  2Y3R A;  1ZR6 A;  2I0K A;  1W1K A;  1N5W C;  1W1O A;  1N62 C;  5FXF A;  1I19 A;  5ADZ A;  3LLB A;  4BCA A;  3GSY A;  1W1Q A;  4ZOH B;  3AN1 A;  4BBY A;  1JRP A;  2UUU A;  1N5X A;  1E8H A;  5HQX A;  3NS1 B;  1N61 C;  3D2J A;  2YVS A;  1W1M A;  5D79 A;  1HSK A;  3NVV B;  5FXP A;  1FO4 A;  2W55 A;  4DNS A;  3PQB A;  3AM9 A;  3TSJ A;  1DZN A;  1AHZ A;  3RJ8 A;  2E3T A;  1WYG A;  2BVF A;  2UUV A;  2R2Z A;  2RK5 A;  2VFT A;  4BC7 A;  1DII A;  2EXR A;  3SR6 B;  3ETR B;  3TSH A;  4JAY A;  2PLS A;  4EC3 A;  2QPM A;  1MBB A;  3FW8 A;  2PLI A;  3S1D A;  2QKN A;  2Y3S A;  3NVW B;  1E0Y A;  2Q4W A;  4MLA A;  1FFU C;  3RJA A;  4XLO A;  5AWV A;  2VAO A;  4HG0 A;  5I1V A;  3FW9 A;  2OAI A;  3EUB 3;  3FWA A;  1ZXI C;  5HHZ A;  4PWB A;  2P13 A;  1E8F A;  4JB1 A;  1T3Q C;  2Y08 A;  4UD8 A;  2AXR A;  1W1S A;  2GQT A;  4BC9 A;  3JS8 A;  1DIQ A;  1FIQ B;  3LAE A;  2R8D A;  5G5G B;  2IPI A;  2P4P A;  1AHU A;  5AE1 A;  2VFU A;  2VFR A;  3KJM A;  3HRD C;  1FFV C;  5G5H B;  1QLU A;  3FW7 A;  5HMR A;  5AE3 A;  2MBR A;  1F0X A;  3NVY B;  5L6F A;  4OAL A;  5FXD A;  1UXY A;  4PVJ A;  1VDV A;  1W1R A;  3C0P A;  3S1E A;  3HSU A;  1RM6 B;  3TX1 A;  1V97 A;  1W1J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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