1AHVA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase in complex with 2-nitro-p-cresol
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
555
structure length
555
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISSKDQIVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
pubmed doi rcsb
molecule tags Flavoenzyme
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 165
structure length 555
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 1997-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1ahvA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1ahvA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1ahvA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1ahvA03
4PYTA 1W1RA 2AXRA 3JS8A 2OAIA 2VFRA 5FXPA 1QLUA 1N5XA 3AN1A 4PZFA 4PVJA 1AHVA 2P3HA 2O3GA 1E0YA 3GSYA 3NVZB 2MBRA 4MLAA 3BW7A 3D2DA 3NVWB 2VAOA 1ZR6A 2BVHA 1FIQB 4BC7A 3B9JB 3S1EA 4ZOHB 3ETRB 1N61C 2QKNA 2PLIA 4PVEA 1QLTA 1JRPA 3C0PA 3LAEA 5AE1A 4PVKA 5ADZA 2I0KA 1N62C 5FXFA 2GQTA 3D2HA 3FW7A 3TX1A 2W55A 1WVFA 3AM9A 1W1QA 5HQXA 3HRDC 3NS1B 5HMRA 2VFUA 4PWCA 5G5HB 2EXRA 1AHUA 1SB3B 1F0XA 3VTEA 1N60C 3FW9A 1N63C 3EUB3 1W1KA 5D79A 3TSJA 5G5GB 3DEDA 1E8GA 2R8DA 1FFVC 1VAOA 1FFUC 2E3TA 4O95A 2P4PA 3W8XA 1FO4A 3TSHA 1ZXIC 1DZNA 3FW8A 1V97A 4BBYA 4BC9A 1DIQA 1DIIA 2W54A 2VFSA 5HHZA 3DQ0A 4JB1A 2Q85A 3S1FA 5AE2A 4JAYA 5FXDA 2RK5A 1HSKA 3S1DA 4EC3A 1VDVA 3LLBA 2Q4WA 3I99A 1WYGA 1WVEA 4OALA 2R2ZA 1W1JA 2BVGA 2W3RA 1UXYA 5AE3A 4BCAA 4XLOA 2GQUA 1RM6B 1I19A 3PM9A 4PWBA 1E8FA 1W1SA 2VFTA 3S1CA 2QPMA 2BVFA 3SR6B 4HG0A 1E8HA 4ML8A 2VFVA 1MBBA 1T3QC 1W1OA 3NVVB 3KJMA 4UD8A 3W8ZA 3NRZB 4DNSA 5FXEA 3NVYB 1W1LA 3FWAA 1AHZA 2NQWA 1MBTA 4PVHA 1JROA 3W8WA 1N5WC 2PLSA 1W1MA 2P13A 3AMZA 2YVSA 2W3SA 3D2JA
chains in the Genus database with same CATH superfamily
4PYTA 1W1RA 2AXRA 3JS8A 2OAIA 2VFRA 5FXPA 1QLUA 1N5XA 3AN1A 4PZFA 4PVJA 1AHVA 2P3HA 2O3GA 1E0YA 3POPA 3GSYA 3NVZB 5AWVA 2MBRA 2UUUA 4MLAA 3BW7A 3D2DA 3NVWB 2VAOA 1ZR6A 2BVHA 1FIQB 4BC7A 3B9JB 3S1EA 5I1VA 4ZOHB 3ETRB 1N61C 2QKNA 2PLIA 4PVEA 1QLTA 3EJEB 3EJDB 1JRPA 3C0PA 3LAEA 5AE1A 4PVKA 5ADZA 2WDWA 2I0KA 1N62C 5FXFA 2GQTA 3D2HA 3FW7A 3TX1A 2W55A 1WVFA 3AM9A 1W1QA 5HQXA 3HRDC 3NS1B 3RJ8A 5HMRA 2VFUA 4PWCA 5I1WA 2IPIA 5G5HB 2EXRA 1AHUA 1SB3B 1F0XA 3VTEA 1N60C 3FW9A 1N63C 3EUB3 1W1KA 5D79A 3TSJA 5G5GB 3DEDA 1E8GA 2R8DA 1FFVC 1VAOA 1FFUC 2E3TA 4O95A 2P4PA 3W8XA 1FO4A 3TSHA 1ZXIC 1DZNA 3FW8A 3HSUA 1V97A 4BBYA 4BC9A 1DIQA 1DIIA 2W54A 2VFSA 2Y08A 5HHZA 3DQ0A 4JB1A 2Q85A 3S1FA 5AE2A 4JAYA 5FXDA 2RK5A 1HSKA 3S1DA 4EC3A 1VDVA 3LLBA 3RJAA 2Q4WA 3I99A 5L6FA 1WYGA 1WVEA 4OALA 2R2ZA 2UUVA 5K8EA 1W1JA 2BVGA 2W3RA 1UXYA 5AE3A 4BCAA 4XLOA 2GQUA 1RM6B 1I19A 5L6GA 3PM9A 4PWBA 1E8FA 1W1SA 2VFTA 3S1CA 2QPMA 2BVFA 3SR6B 4HG0A 1E8HA 3PQBA 4ML8A 2VFVA 2Y3SA 1MBBA 1T3QC 2Y3RA 1W1OA 3NVVB 3KJMA 4UD8A 2Y4GA 3W8ZA 3NRZB 4DNSA 5FXEA 3NVYB 3EJBB 1W1LA 3FWAA 1AHZA 2NQWA 1MBTA 4PVHA 1JROA 3W8WA 1N5WC 2PLSA 1W1MA 2P13A 3AMZA 2YVSA 2W3SA 3D2JA
chains in the Genus database with same CATH topology
4PYTA 1W1RA 2AXRA 3JS8A 2OAIA 2VFRA 5FXPA 1QLUA 1N5XA 3AN1A 4PZFA 4PVJA 1AHVA 2P3HA 2O3GA 1E0YA 3POPA 3GSYA 3NVZB 5AWVA 2MBRA 2UUUA 4MLAA 3BW7A 3D2DA 3NVWB 2VAOA 1ZR6A 2BVHA 1FIQB 4BC7A 3B9JB 3S1EA 5I1VA 4ZOHB 3ETRB 1N61C 2QKNA 2PLIA 4PVEA 1QLTA 1JRPA 3C0PA 3LAEA 5AE1A 4PVKA 5ADZA 2WDWA 2I0KA 1N62C 5FXFA 2GQTA 3D2HA 3FW7A 3TX1A 2W55A 1WVFA 3AM9A 1W1QA 5HQXA 3HRDC 3NS1B 3RJ8A 5HMRA 2VFUA 4PWCA 5I1WA 2IPIA 5G5HB 2EXRA 1AHUA 1SB3B 1F0XA 3VTEA 1N60C 3FW9A 1N63C 3EUB3 1W1KA 5D79A 3TSJA 5G5GB 3DEDA 1E8GA 2R8DA 1FFVC 1VAOA 1FFUC 2E3TA 4O95A 2P4PA 3W8XA 1FO4A 3TSHA 1ZXIC 1DZNA 3FW8A 3HSUA 1V97A 4BBYA 4BC9A 1DIQA 1DIIA 2W54A 2VFSA 2Y08A 5HHZA 3DQ0A 4JB1A 2Q85A 3S1FA 5AE2A 4JAYA 5FXDA 2RK5A 1HSKA 3S1DA 4EC3A 1VDVA 3LLBA 3RJAA 2Q4WA 3I99A 5L6FA 1WYGA 1WVEA 4OALA 2R2ZA 2UUVA 5K8EA 1W1JA 2BVGA 2W3RA 1UXYA 5AE3A 4BCAA 4XLOA 2GQUA 1RM6B 1I19A 5L6GA 3PM9A 4PWBA 1E8FA 1W1SA 2VFTA 3S1CA 2QPMA 2BVFA 3SR6B 4HG0A 1E8HA 3PQBA 4ML8A 2VFVA 2Y3SA 1MBBA 1T3QC 2Y3RA 1W1OA 3NVVB 3KJMA 4UD8A 2Y4GA 3W8ZA 3NRZB 4DNSA 5FXEA 3NVYB 1W1LA 3FWAA 1AHZA 2NQWA 1MBTA 4PVHA 1JROA 3W8WA 1N5WC 2PLSA 1W1MA 2P13A 3AMZA 2YVSA 2W3SA 3D2JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PYT A;  1W1R A;  2AXR A;  3JS8 A;  2OAI A;  2VFR A;  5FXP A;  1QLU A;  1N5X A;  3AN1 A;  4PZF A;  4PVJ A;  1AHV A;  2P3H A;  2O3G A;  1E0Y A;  3GSY A;  3NVZ B;  2MBR A;  4MLA A;  3BW7 A;  3D2D A;  3NVW B;  2VAO A;  1ZR6 A;  2BVH A;  1FIQ B;  4BC7 A;  3B9J B;  3S1E A;  4ZOH B;  3ETR B;  1N61 C;  2QKN A;  2PLI A;  4PVE A;  1QLT A;  1JRP A;  3C0P A;  3LAE A;  5AE1 A;  4PVK A;  5ADZ A;  2I0K A;  1N62 C;  5FXF A;  2GQT A;  3D2H A;  3FW7 A;  3TX1 A;  2W55 A;  1WVF A;  3AM9 A;  1W1Q A;  5HQX A;  3HRD C;  3NS1 B;  5HMR A;  2VFU A;  4PWC A;  5G5H B;  2EXR A;  1AHU A;  1SB3 B;  1F0X A;  3VTE A;  1N60 C;  3FW9 A;  1N63 C;  3EUB 3;  1W1K A;  5D79 A;  3TSJ A;  5G5G B;  3DED A;  1E8G A;  2R8D A;  1FFV C;  1VAO A;  1FFU C;  2E3T A;  4O95 A;  2P4P A;  3W8X A;  1FO4 A;  3TSH A;  1ZXI C;  1DZN A;  3FW8 A;  1V97 A;  4BBY A;  4BC9 A;  1DIQ A;  1DII A;  2W54 A;  2VFS A;  5HHZ A;  3DQ0 A;  4JB1 A;  2Q85 A;  3S1F A;  5AE2 A;  4JAY A;  5FXD A;  2RK5 A;  1HSK A;  3S1D A;  4EC3 A;  1VDV A;  3LLB A;  2Q4W A;  3I99 A;  1WYG A;  1WVE A;  4OAL A;  2R2Z A;  1W1J A;  2BVG A;  2W3R A;  1UXY A;  5AE3 A;  4BCA A;  4XLO A;  2GQU A;  1RM6 B;  1I19 A;  3PM9 A;  4PWB A;  1E8F A;  1W1S A;  2VFT A;  3S1C A;  2QPM A;  2BVF A;  3SR6 B;  4HG0 A;  1E8H A;  4ML8 A;  2VFV A;  1MBB A;  1T3Q C;  1W1O A;  3NVV B;  3KJM A;  4UD8 A;  3W8Z A;  3NRZ B;  4DNS A;  5FXE A;  3NVY B;  1W1L A;  3FWA A;  1AHZ A;  2NQW A;  1MBT A;  4PVH A;  1JRO A;  3W8W A;  1N5W C;  2PLS A;  1W1M A;  2P13 A;  3AMZ A;  2YVS A;  2W3S A;  3D2J A; 
#chains in the Genus database with same CATH topology
 4PYT A;  1W1R A;  2AXR A;  3JS8 A;  2OAI A;  2VFR A;  5FXP A;  1QLU A;  1N5X A;  3AN1 A;  4PZF A;  4PVJ A;  1AHV A;  2P3H A;  2O3G A;  1E0Y A;  3POP A;  3GSY A;  3NVZ B;  5AWV A;  2MBR A;  2UUU A;  4MLA A;  3BW7 A;  3D2D A;  3NVW B;  2VAO A;  1ZR6 A;  2BVH A;  1FIQ B;  4BC7 A;  3B9J B;  3S1E A;  5I1V A;  4ZOH B;  3ETR B;  1N61 C;  2QKN A;  2PLI A;  4PVE A;  1QLT A;  3EJE B;  3EJD B;  1JRP A;  3C0P A;  3LAE A;  5AE1 A;  4PVK A;  5ADZ A;  2WDW A;  2I0K A;  1N62 C;  5FXF A;  2GQT A;  3D2H A;  3FW7 A;  3TX1 A;  2W55 A;  1WVF A;  3AM9 A;  1W1Q A;  5HQX A;  3HRD C;  3NS1 B;  3RJ8 A;  5HMR A;  2VFU A;  4PWC A;  5I1W A;  2IPI A;  5G5H B;  2EXR A;  1AHU A;  1SB3 B;  1F0X A;  3VTE A;  1N60 C;  3FW9 A;  1N63 C;  3EUB 3;  1W1K A;  5D79 A;  3TSJ A;  5G5G B;  3DED A;  1E8G A;  2R8D A;  1FFV C;  1VAO A;  1FFU C;  2E3T A;  4O95 A;  2P4P A;  3W8X A;  1FO4 A;  3TSH A;  1ZXI C;  1DZN A;  3FW8 A;  3HSU A;  1V97 A;  4BBY A;  4BC9 A;  1DIQ A;  1DII A;  2W54 A;  2VFS A;  2Y08 A;  5HHZ A;  3DQ0 A;  4JB1 A;  2Q85 A;  3S1F A;  5AE2 A;  4JAY A;  5FXD A;  2RK5 A;  1HSK A;  3S1D A;  4EC3 A;  1VDV A;  3LLB A;  3RJA A;  2Q4W A;  3I99 A;  5L6F A;  1WYG A;  1WVE A;  4OAL A;  2R2Z A;  2UUV A;  5K8E A;  1W1J A;  2BVG A;  2W3R A;  1UXY A;  5AE3 A;  4BCA A;  4XLO A;  2GQU A;  1RM6 B;  1I19 A;  5L6G A;  3PM9 A;  4PWB A;  1E8F A;  1W1S A;  2VFT A;  3S1C A;  2QPM A;  2BVF A;  3SR6 B;  4HG0 A;  1E8H A;  3PQB A;  4ML8 A;  2VFV A;  2Y3S A;  1MBB A;  1T3Q C;  2Y3R A;  1W1O A;  3NVV B;  3KJM A;  4UD8 A;  2Y4G A;  3W8Z A;  3NRZ B;  4DNS A;  5FXE A;  3NVY B;  3EJB B;  1W1L A;  3FWA A;  1AHZ A;  2NQW A;  1MBT A;  4PVH A;  1JRO A;  3W8W A;  1N5W C;  2PLS A;  1W1M A;  2P13 A;  3AMZ A;  2YVS A;  2W3S A;  3D2J A; 
#chains in the Genus database with same CATH homology
 4PYT A;  1W1R A;  2AXR A;  3JS8 A;  2OAI A;  2VFR A;  5FXP A;  1QLU A;  1N5X A;  3AN1 A;  4PZF A;  4PVJ A;  1AHV A;  2P3H A;  2O3G A;  1E0Y A;  3POP A;  3GSY A;  3NVZ B;  5AWV A;  2MBR A;  2UUU A;  4MLA A;  3BW7 A;  3D2D A;  3NVW B;  2VAO A;  1ZR6 A;  2BVH A;  1FIQ B;  4BC7 A;  3B9J B;  3S1E A;  5I1V A;  4ZOH B;  3ETR B;  1N61 C;  2QKN A;  2PLI A;  4PVE A;  1QLT A;  1JRP A;  3C0P A;  3LAE A;  5AE1 A;  4PVK A;  5ADZ A;  2WDW A;  2I0K A;  1N62 C;  5FXF A;  2GQT A;  3D2H A;  3FW7 A;  3TX1 A;  2W55 A;  1WVF A;  3AM9 A;  1W1Q A;  5HQX A;  3HRD C;  3NS1 B;  3RJ8 A;  5HMR A;  2VFU A;  4PWC A;  5I1W A;  2IPI A;  5G5H B;  2EXR A;  1AHU A;  1SB3 B;  1F0X A;  3VTE A;  1N60 C;  3FW9 A;  1N63 C;  3EUB 3;  1W1K A;  5D79 A;  3TSJ A;  5G5G B;  3DED A;  1E8G A;  2R8D A;  1FFV C;  1VAO A;  1FFU C;  2E3T A;  4O95 A;  2P4P A;  3W8X A;  1FO4 A;  3TSH A;  1ZXI C;  1DZN A;  3FW8 A;  3HSU A;  1V97 A;  4BBY A;  4BC9 A;  1DIQ A;  1DII A;  2W54 A;  2VFS A;  2Y08 A;  5HHZ A;  3DQ0 A;  4JB1 A;  2Q85 A;  3S1F A;  5AE2 A;  4JAY A;  5FXD A;  2RK5 A;  1HSK A;  3S1D A;  4EC3 A;  1VDV A;  3LLB A;  3RJA A;  2Q4W A;  3I99 A;  5L6F A;  1WYG A;  1WVE A;  4OAL A;  2R2Z A;  2UUV A;  5K8E A;  1W1J A;  2BVG A;  2W3R A;  1UXY A;  5AE3 A;  4BCA A;  4XLO A;  2GQU A;  1RM6 B;  1I19 A;  5L6G A;  3PM9 A;  4PWB A;  1E8F A;  1W1S A;  2VFT A;  3S1C A;  2QPM A;  2BVF A;  3SR6 B;  4HG0 A;  1E8H A;  3PQB A;  4ML8 A;  2VFV A;  2Y3S A;  1MBB A;  1T3Q C;  2Y3R A;  1W1O A;  3NVV B;  3KJM A;  4UD8 A;  2Y4G A;  3W8Z A;  3NRZ B;  4DNS A;  5FXE A;  3NVY B;  1W1L A;  3FWA A;  1AHZ A;  2NQW A;  1MBT A;  4PVH A;  1JRO A;  3W8W A;  1N5W C;  2PLS A;  1W1M A;  2P13 A;  3AMZ A;  2YVS A;  2W3S A;  3D2J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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