3POPA

The crystal structure of gilr, an oxidoreductase that catalyzes the terminal step of gilvocarcin biosynthesis
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
493
structure length
493
Chain Sequence
PPFTVGREDPRYIELSHSDNHRFVVEPEEFFLPATPDDVVASLQKAVTEGRGVACRSGGHCGQDFVGTPRRDLVLDLHNLHAIGPAADGAGVRVGSGATVDQVQKALFRRWNAALPLGACSAVGMGGLVAGGGYGPLSRQLGLVVDHLHAVEVAVVDESRTVRLVTARADDTGDLGELFWAHTGGGGGNFGVVTAYEFRSPEHLATEPVGLPRAAGRLHVQKVVFPWAMIDETSFVTVMRRFFEWHERHSEPGSPESSLFATFFVNHVSSGVLQLMVQQDADVDPEGEILARFVASLTEGTGVVGIPRGGVMSWLTGTRYMSQADCGDVMGARSASKSAYHRAAPTDEQLSVLHRHLHADHPGQASYVMFNSYGGEINRRGPSDAAVPQRDSVVKSSWFSAWQDAELDELHLGWLRGLYEEFFAGTGGVPVTGGRTDGCYINYPDADLLDPARNRSGEPWHHLYYKDNYARLRSAKRAWDPLNTFHHSMSIGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis.
pubmed doi rcsb
source organism Streptomyces griseoflavus
molecule tags Oxidoreductase
molecule keywords GilR oxidase
total genus 161
structure length 493
sequence length 493
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.465.40 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3popA01
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3popA02
3FWAA 2Y3RA 5I1WA 3RJ8A 3FW9A 3FW8A 2UUUA 2Y4GA 2Y3SA 3GSYA 2IPIA 4PVKA 1ZR6A 5K8EA 2UUVA 5L6GA 3D2DA 3FW7A 2WDWA 4PVJA 3TSHA 5D79A 4PZFA 2BVFA 4PWCA 3D2HA 3RJAA 2AXRA 3POPA 4DNSA 5I1VA 4UD8A 4EC3A 3PQBA 2BVHA 3VTEA 3D2JA 4PVEA 5L6FA 4XLOA 3W8WA 5AWVA 4PWBA 3TSJA 3W8XA 4PVHA 3W8ZA 2Y08A 3HSUA 2BVGA
chains in the Genus database with same CATH superfamily
1E8GA 2EXRA 5HQXA 4BC9A 3AM9A 2QKNA 1FFUC 1W1MA 1JROA 3FW9A 5G5HB 1E0YA 5FXDA 3GSYA 2Y4GA 2P13A 2IPIA 5G5GB 1ZR6A 2E3TA 2UUVA 1QLTA 5AE1A 1MBTA 3BW7A 2W55A 3D2DA 1DIQA 2VFVA 1I19A 5FXFA 2W3RA 2RK5A 2QPMA 2BVFA 2VFTA 4PZFA 1N63C 2AXRA 2R2ZA 1W1JA 4EC3A 3VTEA 1N5WC 5FXEA 2P3HA 1AHZA 3LLBA 4HG0A 4PWBA 3TSJA 4PVHA 3W8ZA 2VFUA 2Y08A 2R8DA 5HHZA 2GQTA 4PYTA 1N60C 1RM6B 1W1KA 2NQWA 3S1CA 2Y3SA 4PVKA 3JS8A 1N5XA 3NRZB 3EUB3 5FXPA 4BC7A 1E8HA 5L6GA 2PLIA 2GQUA 3NVVB 2VAOA 2VFSA 5D79A 4DNSA 1DZNA 2BVHA 3PQBA 3HRDC 4ZOHB 4JAYA 3NVYB 2W3SA 5ADZA 1W1LA 5AWVA 3W8XA 5AE2A 3S1DA 1W1OA 3RJ8A 1FIQB 3SR6B 2Q85A 3S1EA 2VFRA 1UXYA 1F0XA 1ZXIC 1WVEA 3DEDA 2PLSA 3DQ0A 3FW7A 1E8FA 1WVFA 1SB3B 4PWCA 1QLUA 3I99A 4UD8A 5I1VA 2YVSA 1W1SA 3D2JA 3PM9A 1WYGA 1FO4A 1AHUA 4PVEA 1V97A 1W1RA 4JB1A 4XLOA 5L6FA 3LAEA 5AE3A 3NVWB 1VDVA 3D2HA 1AHVA 2BVGA 1JRPA 3FWAA 2Y3RA 5I1WA 4OALA 2W54A 3FW8A 2UUUA 3NVZB 2O3GA 5K8EA 3NS1B 2Q4WA 4BCAA 2OAIA 3S1FA 4ML8A 1N62C 2WDWA 4PVJA 5HMRA 3TX1A 3TSHA 1FFVC 1N61C 3AN1A 3B9JB 1DIIA 3C0PA 3KJMA 3POPA 3RJAA 1MBBA 2P4PA 1W1QA 4O95A 3AMZA 1T3QC 3ETRB 4BBYA 1HSKA 3W8WA 4MLAA 1VAOA 2I0KA 3HSUA 2MBRA
chains in the Genus database with same CATH topology
1E8GA 2EXRA 5HQXA 4BC9A 3AM9A 2QKNA 1FFUC 1W1MA 1JROA 3FW9A 5G5HB 1E0YA 5FXDA 3GSYA 2Y4GA 2P13A 2IPIA 5G5GB 1ZR6A 2E3TA 2UUVA 1QLTA 5AE1A 1MBTA 3BW7A 2W55A 3D2DA 1DIQA 2VFVA 1I19A 5FXFA 2W3RA 2RK5A 2QPMA 2BVFA 2VFTA 4PZFA 1N63C 2AXRA 2R2ZA 1W1JA 4EC3A 3VTEA 1N5WC 5FXEA 2P3HA 1AHZA 3LLBA 4HG0A 4PWBA 3TSJA 4PVHA 3W8ZA 2VFUA 2Y08A 2R8DA 5HHZA 2GQTA 4PYTA 1N60C 1RM6B 1W1KA 2NQWA 3S1CA 2Y3SA 4PVKA 3JS8A 1N5XA 3NRZB 3EUB3 5FXPA 4BC7A 1E8HA 5L6GA 2PLIA 2GQUA 3NVVB 2VAOA 2VFSA 5D79A 4DNSA 1DZNA 2BVHA 3PQBA 3HRDC 4ZOHB 4JAYA 3NVYB 2W3SA 5ADZA 1W1LA 5AWVA 3W8XA 5AE2A 3S1DA 1W1OA 3RJ8A 1FIQB 3SR6B 2Q85A 3S1EA 2VFRA 1UXYA 1F0XA 1ZXIC 1WVEA 3DEDA 2PLSA 3DQ0A 3FW7A 1E8FA 1WVFA 1SB3B 4PWCA 1QLUA 3I99A 4UD8A 5I1VA 2YVSA 1W1SA 3D2JA 3PM9A 1WYGA 1FO4A 1AHUA 4PVEA 1V97A 1W1RA 4JB1A 4XLOA 5L6FA 3LAEA 5AE3A 3NVWB 1VDVA 3D2HA 1AHVA 2BVGA 1JRPA 3FWAA 2Y3RA 5I1WA 4OALA 2W54A 3FW8A 2UUUA 3NVZB 2O3GA 5K8EA 3NS1B 2Q4WA 4BCAA 2OAIA 3S1FA 4ML8A 1N62C 2WDWA 4PVJA 5HMRA 3TX1A 3TSHA 1FFVC 1N61C 3AN1A 3B9JB 1DIIA 3C0PA 3KJMA 3POPA 3RJAA 1MBBA 2P4PA 1W1QA 4O95A 3AMZA 1T3QC 3ETRB 4BBYA 1HSKA 3W8WA 4MLAA 1VAOA 2I0KA 3HSUA 2MBRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FWA A;  2Y3R A;  5I1W A;  3RJ8 A;  3FW9 A;  3FW8 A;  2UUU A;  2Y4G A;  2Y3S A;  3GSY A;  2IPI A;  4PVK A;  1ZR6 A;  5K8E A;  2UUV A;  5L6G A;  3D2D A;  3FW7 A;  2WDW A;  4PVJ A;  3TSH A;  5D79 A;  4PZF A;  2BVF A;  4PWC A;  3D2H A;  3RJA A;  2AXR A;  3POP A;  4DNS A;  5I1V A;  4UD8 A;  4EC3 A;  3PQB A;  2BVH A;  3VTE A;  3D2J A;  4PVE A;  5L6F A;  4XLO A;  3W8W A;  5AWV A;  4PWB A;  3TSJ A;  3W8X A;  4PVH A;  3W8Z A;  2Y08 A;  3HSU A;  2BVG A; 
#chains in the Genus database with same CATH topology
 1E8G A;  2EXR A;  5HQX A;  4BC9 A;  3AM9 A;  2QKN A;  1FFU C;  1W1M A;  1JRO A;  3FW9 A;  5G5H B;  1E0Y A;  5FXD A;  3GSY A;  2Y4G A;  2P13 A;  2IPI A;  5G5G B;  1ZR6 A;  2E3T A;  2UUV A;  1QLT A;  5AE1 A;  1MBT A;  3BW7 A;  2W55 A;  3D2D A;  1DIQ A;  2VFV A;  1I19 A;  5FXF A;  2W3R A;  2RK5 A;  2QPM A;  2BVF A;  2VFT A;  4PZF A;  1N63 C;  2AXR A;  2R2Z A;  1W1J A;  4EC3 A;  3VTE A;  1N5W C;  5FXE A;  2P3H A;  1AHZ A;  3LLB A;  4HG0 A;  4PWB A;  3TSJ A;  4PVH A;  3W8Z A;  2VFU A;  2Y08 A;  2R8D A;  5HHZ A;  2GQT A;  4PYT A;  1N60 C;  1RM6 B;  1W1K A;  2NQW A;  3S1C A;  2Y3S A;  4PVK A;  3JS8 A;  1N5X A;  3NRZ B;  3EUB 3;  5FXP A;  4BC7 A;  1E8H A;  5L6G A;  2PLI A;  2GQU A;  3NVV B;  2VAO A;  2VFS A;  5D79 A;  4DNS A;  1DZN A;  2BVH A;  3PQB A;  3HRD C;  4ZOH B;  4JAY A;  3NVY B;  2W3S A;  5ADZ A;  1W1L A;  5AWV A;  3W8X A;  5AE2 A;  3S1D A;  1W1O A;  3RJ8 A;  1FIQ B;  3SR6 B;  2Q85 A;  3S1E A;  2VFR A;  1UXY A;  1F0X A;  1ZXI C;  1WVE A;  3DED A;  2PLS A;  3DQ0 A;  3FW7 A;  1E8F A;  1WVF A;  1SB3 B;  4PWC A;  1QLU A;  3I99 A;  4UD8 A;  5I1V A;  2YVS A;  1W1S A;  3D2J A;  3PM9 A;  1WYG A;  1FO4 A;  1AHU A;  4PVE A;  1V97 A;  1W1R A;  4JB1 A;  4XLO A;  5L6F A;  3LAE A;  5AE3 A;  3NVW B;  1VDV A;  3D2H A;  1AHV A;  2BVG A;  1JRP A;  3FWA A;  2Y3R A;  5I1W A;  4OAL A;  2W54 A;  3FW8 A;  2UUU A;  3NVZ B;  2O3G A;  5K8E A;  3NS1 B;  2Q4W A;  4BCA A;  2OAI A;  3S1F A;  4ML8 A;  1N62 C;  2WDW A;  4PVJ A;  5HMR A;  3TX1 A;  3TSH A;  1FFV C;  1N61 C;  3AN1 A;  3B9J B;  1DII A;  3C0P A;  3KJM A;  3POP A;  3RJA A;  1MBB A;  2P4P A;  1W1Q A;  4O95 A;  3AMZ A;  1T3Q C;  3ETR B;  4BBY A;  1HSK A;  3W8W A;  4MLA A;  1VAO A;  2I0K A;  3HSU A;  2MBR A; 
#chains in the Genus database with same CATH homology
 1E8G A;  2EXR A;  5HQX A;  4BC9 A;  3AM9 A;  2QKN A;  1FFU C;  1W1M A;  1JRO A;  3FW9 A;  5G5H B;  1E0Y A;  5FXD A;  3GSY A;  2Y4G A;  2P13 A;  2IPI A;  5G5G B;  1ZR6 A;  2E3T A;  2UUV A;  1QLT A;  5AE1 A;  1MBT A;  3BW7 A;  2W55 A;  3D2D A;  1DIQ A;  2VFV A;  1I19 A;  5FXF A;  2W3R A;  2RK5 A;  2QPM A;  2BVF A;  2VFT A;  4PZF A;  1N63 C;  2AXR A;  2R2Z A;  1W1J A;  4EC3 A;  3VTE A;  1N5W C;  5FXE A;  2P3H A;  1AHZ A;  3LLB A;  4HG0 A;  4PWB A;  3TSJ A;  4PVH A;  3W8Z A;  2VFU A;  2Y08 A;  2R8D A;  5HHZ A;  2GQT A;  4PYT A;  1N60 C;  1RM6 B;  1W1K A;  2NQW A;  3S1C A;  2Y3S A;  4PVK A;  3JS8 A;  1N5X A;  3NRZ B;  3EUB 3;  5FXP A;  4BC7 A;  1E8H A;  5L6G A;  2PLI A;  2GQU A;  3NVV B;  2VAO A;  2VFS A;  5D79 A;  4DNS A;  1DZN A;  2BVH A;  3PQB A;  3HRD C;  4ZOH B;  4JAY A;  3NVY B;  2W3S A;  5ADZ A;  1W1L A;  5AWV A;  3W8X A;  5AE2 A;  3S1D A;  1W1O A;  3RJ8 A;  1FIQ B;  3SR6 B;  2Q85 A;  3S1E A;  2VFR A;  1UXY A;  1F0X A;  1ZXI C;  1WVE A;  3DED A;  2PLS A;  3DQ0 A;  3FW7 A;  1E8F A;  1WVF A;  1SB3 B;  4PWC A;  1QLU A;  3I99 A;  4UD8 A;  5I1V A;  2YVS A;  1W1S A;  3D2J A;  3PM9 A;  1WYG A;  1FO4 A;  1AHU A;  4PVE A;  1V97 A;  1W1R A;  4JB1 A;  4XLO A;  5L6F A;  3LAE A;  5AE3 A;  3NVW B;  1VDV A;  3D2H A;  1AHV A;  2BVG A;  1JRP A;  3FWA A;  2Y3R A;  5I1W A;  4OAL A;  2W54 A;  3FW8 A;  2UUU A;  3NVZ B;  2O3G A;  5K8E A;  3NS1 B;  2Q4W A;  4BCA A;  2OAI A;  3S1F A;  4ML8 A;  1N62 C;  2WDW A;  4PVJ A;  5HMR A;  3TX1 A;  3TSH A;  1FFV C;  1N61 C;  3AN1 A;  3B9J B;  1DII A;  3C0P A;  3KJM A;  3POP A;  3RJA A;  1MBB A;  2P4P A;  1W1Q A;  4O95 A;  3AMZ A;  1T3Q C;  3ETR B;  4BBY A;  1HSK A;  3W8W A;  4MLA A;  1VAO A;  2I0K A;  3HSU A;  2MBR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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