1W1JA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: the505ser mutant
Total Genus 178
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
178
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRSHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
source organism Penicillium simplicissimum
molecule tags Oxidoreductase
total genus 178
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1jA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1jA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1jA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1jA03
2VFSA 1QLTA 2VFVA 3SR6B 5HMRA 4PVHA 1T3QC 1N63C 4PZFA 3B9JB 2NQWA 2W3SA 5FXFA 3W8WA 2P13A 2GQUA 2AXRA 4PWCA 2VFUA 3FWAA 4OALA 1DIIA 1N5XA 3FW9A 1MBBA 2MBRA 2W3RA 5FXDA 3AMZA 3I99A 3AN1A 1RM6B 1DZNA 3NVWB 5FXEA 2GQTA 4MLAA 3AM9A 4XLOA 2BVHA 1JRPA 2W54A 3JS8A 5G5HB 4O95A 1FFVC 3VTEA 1WYGA 3S1EA 1FIQB 4JB1A 2PLSA 4ZOHB 2I0KA 1N5WC 4UD8A 2PLIA 5FXPA 1QLUA 3FW8A 3KJMA 3C0PA 3S1FA 1SB3B 4BCAA 4PYTA 5HHZA 1N62C 3GSYA 3PM9A 1E8GA 1E8FA 2W55A 1W1LA 4PVEA 4ML8A 1MBTA 1VAOA 1VDVA 2EXRA 5G5GB 1AHZA 1F0XA 1DIQA 2BVFA 2VFTA 4PVKA 1ZXIC 3S1DA 2VAOA 4JAYA 3W8XA 2R8DA 3LAEA 2Q85A 3TSHA 1AHUA 2OAIA 1E0YA 3HRDC 3DQ0A 2QKNA 1WVFA 1W1KA 1ZR6A 3ETRB 4DNSA 2R2ZA 3W8ZA 1AHVA 3NVYB 5D79A 3NRZB 3EUB3 4PVJA 3FW7A 2YVSA 2E3TA 1N60C 5AE1A 1W1JA 1N61C 1W1QA 3NS1B 1FO4A 2QPMA 2Q4WA 3DEDA 4BBYA 5AE2A 2RK5A 1HSKA 3S1CA 1WVEA 2VFRA 4BC9A 1W1SA 3TSJA 2P4PA 2BVGA 4BC7A 2O3GA 5ADZA 1W1RA 4HG0A 3LLBA 1UXYA 3NVVB 1E8HA 1W1OA 5AE3A 3D2DA 1V97A 2P3HA 1JROA 4EC3A 3BW7A 3D2JA 4PWBA 1W1MA 5HQXA 3D2HA 1I19A 3TX1A 1FFUC 3NVZB
chains in the Genus database with same CATH superfamily
2VFSA 1QLTA 2VFVA 3SR6B 5HMRA 4PVHA 1T3QC 1N63C 4PZFA 3B9JB 2NQWA 2W3SA 5FXFA 3W8WA 2P13A 2GQUA 2AXRA 4PWCA 3EJEB 2VFUA 3FWAA 4OALA 1DIIA 1N5XA 3FW9A 1MBBA 2MBRA 2W3RA 5FXDA 3EJDB 3AMZA 3I99A 3AN1A 1RM6B 1DZNA 3NVWB 3POPA 5FXEA 2GQTA 4MLAA 5L6GA 3AM9A 4XLOA 5AWVA 2BVHA 1JRPA 2W54A 3JS8A 5G5HB 4O95A 3EJBB 1FFVC 3VTEA 5K8EA 1WYGA 2Y3RA 3S1EA 1FIQB 4JB1A 2PLSA 4ZOHB 2I0KA 2Y4GA 1N5WC 4UD8A 2PLIA 5FXPA 1QLUA 3FW8A 3KJMA 3C0PA 3S1FA 1SB3B 4BCAA 4PYTA 5HHZA 1N62C 3GSYA 3PM9A 1E8GA 1E8FA 2W55A 5L6FA 1W1LA 3PQBA 4PVEA 4ML8A 1MBTA 1VAOA 1VDVA 2EXRA 5G5GB 1AHZA 1F0XA 1DIQA 2BVFA 2VFTA 4PVKA 1ZXIC 3S1DA 2VAOA 4JAYA 3W8XA 2R8DA 3LAEA 2Q85A 3TSHA 1AHUA 2OAIA 3RJAA 1E0YA 3HRDC 3DQ0A 2Y3SA 2QKNA 1WVFA 1W1KA 1ZR6A 3ETRB 4DNSA 2R2ZA 3W8ZA 1AHVA 3RJ8A 3NVYB 5D79A 3NRZB 3EUB3 4PVJA 3FW7A 2UUVA 2YVSA 2E3TA 2UUUA 1N60C 5AE1A 1W1JA 1N61C 1W1QA 3NS1B 1FO4A 2QPMA 2Q4WA 3DEDA 5I1WA 4BBYA 5AE2A 2RK5A 1HSKA 3S1CA 1WVEA 2WDWA 2VFRA 4BC9A 1W1SA 3TSJA 2P4PA 2BVGA 4BC7A 2O3GA 5ADZA 1W1RA 4HG0A 3LLBA 1UXYA 3NVVB 2IPIA 1E8HA 1W1OA 5AE3A 3D2DA 1V97A 2P3HA 1JROA 4EC3A 3BW7A 3D2JA 2Y08A 4PWBA 5I1VA 1W1MA 5HQXA 3D2HA 1I19A 3HSUA 3TX1A 1FFUC 3NVZB
chains in the Genus database with same CATH topology
2VFSA 1QLTA 2VFVA 3SR6B 5HMRA 4PVHA 1T3QC 1N63C 4PZFA 3B9JB 2NQWA 2W3SA 5FXFA 3W8WA 2P13A 2GQUA 2AXRA 4PWCA 2VFUA 3FWAA 4OALA 1DIIA 1N5XA 3FW9A 1MBBA 2MBRA 2W3RA 5FXDA 3AMZA 3I99A 3AN1A 1RM6B 1DZNA 3NVWB 3POPA 5FXEA 2GQTA 4MLAA 5L6GA 3AM9A 4XLOA 5AWVA 2BVHA 1JRPA 2W54A 3JS8A 5G5HB 4O95A 1FFVC 3VTEA 5K8EA 1WYGA 2Y3RA 3S1EA 1FIQB 4JB1A 2PLSA 4ZOHB 2I0KA 2Y4GA 1N5WC 4UD8A 2PLIA 5FXPA 1QLUA 3FW8A 3KJMA 3C0PA 3S1FA 1SB3B 4BCAA 4PYTA 5HHZA 1N62C 3GSYA 3PM9A 1E8GA 1E8FA 2W55A 5L6FA 1W1LA 3PQBA 4PVEA 4ML8A 1MBTA 1VAOA 1VDVA 2EXRA 5G5GB 1AHZA 1F0XA 1DIQA 2BVFA 2VFTA 4PVKA 1ZXIC 3S1DA 2VAOA 4JAYA 3W8XA 2R8DA 3LAEA 2Q85A 3TSHA 1AHUA 2OAIA 3RJAA 1E0YA 3HRDC 3DQ0A 2Y3SA 2QKNA 1WVFA 1W1KA 1ZR6A 3ETRB 4DNSA 2R2ZA 3W8ZA 1AHVA 3RJ8A 3NVYB 5D79A 3NRZB 3EUB3 4PVJA 3FW7A 2UUVA 2YVSA 2E3TA 2UUUA 1N60C 5AE1A 1W1JA 1N61C 1W1QA 3NS1B 1FO4A 2QPMA 2Q4WA 3DEDA 5I1WA 4BBYA 5AE2A 2RK5A 1HSKA 3S1CA 1WVEA 2WDWA 2VFRA 4BC9A 1W1SA 3TSJA 2P4PA 2BVGA 4BC7A 2O3GA 5ADZA 1W1RA 4HG0A 3LLBA 1UXYA 3NVVB 2IPIA 1E8HA 1W1OA 5AE3A 3D2DA 1V97A 2P3HA 1JROA 4EC3A 3BW7A 3D2JA 2Y08A 4PWBA 5I1VA 1W1MA 5HQXA 3D2HA 1I19A 3HSUA 3TX1A 1FFUC 3NVZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VFS A;  1QLT A;  2VFV A;  3SR6 B;  5HMR A;  4PVH A;  1T3Q C;  1N63 C;  4PZF A;  3B9J B;  2NQW A;  2W3S A;  5FXF A;  3W8W A;  2P13 A;  2GQU A;  2AXR A;  4PWC A;  2VFU A;  3FWA A;  4OAL A;  1DII A;  1N5X A;  3FW9 A;  1MBB A;  2MBR A;  2W3R A;  5FXD A;  3AMZ A;  3I99 A;  3AN1 A;  1RM6 B;  1DZN A;  3NVW B;  5FXE A;  2GQT A;  4MLA A;  3AM9 A;  4XLO A;  2BVH A;  1JRP A;  2W54 A;  3JS8 A;  5G5H B;  4O95 A;  1FFV C;  3VTE A;  1WYG A;  3S1E A;  1FIQ B;  4JB1 A;  2PLS A;  4ZOH B;  2I0K A;  1N5W C;  4UD8 A;  2PLI A;  5FXP A;  1QLU A;  3FW8 A;  3KJM A;  3C0P A;  3S1F A;  1SB3 B;  4BCA A;  4PYT A;  5HHZ A;  1N62 C;  3GSY A;  3PM9 A;  1E8G A;  1E8F A;  2W55 A;  1W1L A;  4PVE A;  4ML8 A;  1MBT A;  1VAO A;  1VDV A;  2EXR A;  5G5G B;  1AHZ A;  1F0X A;  1DIQ A;  2BVF A;  2VFT A;  4PVK A;  1ZXI C;  3S1D A;  2VAO A;  4JAY A;  3W8X A;  2R8D A;  3LAE A;  2Q85 A;  3TSH A;  1AHU A;  2OAI A;  1E0Y A;  3HRD C;  3DQ0 A;  2QKN A;  1WVF A;  1W1K A;  1ZR6 A;  3ETR B;  4DNS A;  2R2Z A;  3W8Z A;  1AHV A;  3NVY B;  5D79 A;  3NRZ B;  3EUB 3;  4PVJ A;  3FW7 A;  2YVS A;  2E3T A;  1N60 C;  5AE1 A;  1W1J A;  1N61 C;  1W1Q A;  3NS1 B;  1FO4 A;  2QPM A;  2Q4W A;  3DED A;  4BBY A;  5AE2 A;  2RK5 A;  1HSK A;  3S1C A;  1WVE A;  2VFR A;  4BC9 A;  1W1S A;  3TSJ A;  2P4P A;  2BVG A;  4BC7 A;  2O3G A;  5ADZ A;  1W1R A;  4HG0 A;  3LLB A;  1UXY A;  3NVV B;  1E8H A;  1W1O A;  5AE3 A;  3D2D A;  1V97 A;  2P3H A;  1JRO A;  4EC3 A;  3BW7 A;  3D2J A;  4PWB A;  1W1M A;  5HQX A;  3D2H A;  1I19 A;  3TX1 A;  1FFU C;  3NVZ B; 
#chains in the Genus database with same CATH topology
 2VFS A;  1QLT A;  2VFV A;  3SR6 B;  5HMR A;  4PVH A;  1T3Q C;  1N63 C;  4PZF A;  3B9J B;  2NQW A;  2W3S A;  5FXF A;  3W8W A;  2P13 A;  2GQU A;  2AXR A;  4PWC A;  3EJE B;  2VFU A;  3FWA A;  4OAL A;  1DII A;  1N5X A;  3FW9 A;  1MBB A;  2MBR A;  2W3R A;  5FXD A;  3EJD B;  3AMZ A;  3I99 A;  3AN1 A;  1RM6 B;  1DZN A;  3NVW B;  3POP A;  5FXE A;  2GQT A;  4MLA A;  5L6G A;  3AM9 A;  4XLO A;  5AWV A;  2BVH A;  1JRP A;  2W54 A;  3JS8 A;  5G5H B;  4O95 A;  3EJB B;  1FFV C;  3VTE A;  5K8E A;  1WYG A;  2Y3R A;  3S1E A;  1FIQ B;  4JB1 A;  2PLS A;  4ZOH B;  2I0K A;  2Y4G A;  1N5W C;  4UD8 A;  2PLI A;  5FXP A;  1QLU A;  3FW8 A;  3KJM A;  3C0P A;  3S1F A;  1SB3 B;  4BCA A;  4PYT A;  5HHZ A;  1N62 C;  3GSY A;  3PM9 A;  1E8G A;  1E8F A;  2W55 A;  5L6F A;  1W1L A;  3PQB A;  4PVE A;  4ML8 A;  1MBT A;  1VAO A;  1VDV A;  2EXR A;  5G5G B;  1AHZ A;  1F0X A;  1DIQ A;  2BVF A;  2VFT A;  4PVK A;  1ZXI C;  3S1D A;  2VAO A;  4JAY A;  3W8X A;  2R8D A;  3LAE A;  2Q85 A;  3TSH A;  1AHU A;  2OAI A;  3RJA A;  1E0Y A;  3HRD C;  3DQ0 A;  2Y3S A;  2QKN A;  1WVF A;  1W1K A;  1ZR6 A;  3ETR B;  4DNS A;  2R2Z A;  3W8Z A;  1AHV A;  3RJ8 A;  3NVY B;  5D79 A;  3NRZ B;  3EUB 3;  4PVJ A;  3FW7 A;  2UUV A;  2YVS A;  2E3T A;  2UUU A;  1N60 C;  5AE1 A;  1W1J A;  1N61 C;  1W1Q A;  3NS1 B;  1FO4 A;  2QPM A;  2Q4W A;  3DED A;  5I1W A;  4BBY A;  5AE2 A;  2RK5 A;  1HSK A;  3S1C A;  1WVE A;  2WDW A;  2VFR A;  4BC9 A;  1W1S A;  3TSJ A;  2P4P A;  2BVG A;  4BC7 A;  2O3G A;  5ADZ A;  1W1R A;  4HG0 A;  3LLB A;  1UXY A;  3NVV B;  2IPI A;  1E8H A;  1W1O A;  5AE3 A;  3D2D A;  1V97 A;  2P3H A;  1JRO A;  4EC3 A;  3BW7 A;  3D2J A;  2Y08 A;  4PWB A;  5I1V A;  1W1M A;  5HQX A;  3D2H A;  1I19 A;  3HSU A;  3TX1 A;  1FFU C;  3NVZ B; 
#chains in the Genus database with same CATH homology
 2VFS A;  1QLT A;  2VFV A;  3SR6 B;  5HMR A;  4PVH A;  1T3Q C;  1N63 C;  4PZF A;  3B9J B;  2NQW A;  2W3S A;  5FXF A;  3W8W A;  2P13 A;  2GQU A;  2AXR A;  4PWC A;  2VFU A;  3FWA A;  4OAL A;  1DII A;  1N5X A;  3FW9 A;  1MBB A;  2MBR A;  2W3R A;  5FXD A;  3AMZ A;  3I99 A;  3AN1 A;  1RM6 B;  1DZN A;  3NVW B;  3POP A;  5FXE A;  2GQT A;  4MLA A;  5L6G A;  3AM9 A;  4XLO A;  5AWV A;  2BVH A;  1JRP A;  2W54 A;  3JS8 A;  5G5H B;  4O95 A;  1FFV C;  3VTE A;  5K8E A;  1WYG A;  2Y3R A;  3S1E A;  1FIQ B;  4JB1 A;  2PLS A;  4ZOH B;  2I0K A;  2Y4G A;  1N5W C;  4UD8 A;  2PLI A;  5FXP A;  1QLU A;  3FW8 A;  3KJM A;  3C0P A;  3S1F A;  1SB3 B;  4BCA A;  4PYT A;  5HHZ A;  1N62 C;  3GSY A;  3PM9 A;  1E8G A;  1E8F A;  2W55 A;  5L6F A;  1W1L A;  3PQB A;  4PVE A;  4ML8 A;  1MBT A;  1VAO A;  1VDV A;  2EXR A;  5G5G B;  1AHZ A;  1F0X A;  1DIQ A;  2BVF A;  2VFT A;  4PVK A;  1ZXI C;  3S1D A;  2VAO A;  4JAY A;  3W8X A;  2R8D A;  3LAE A;  2Q85 A;  3TSH A;  1AHU A;  2OAI A;  3RJA A;  1E0Y A;  3HRD C;  3DQ0 A;  2Y3S A;  2QKN A;  1WVF A;  1W1K A;  1ZR6 A;  3ETR B;  4DNS A;  2R2Z A;  3W8Z A;  1AHV A;  3RJ8 A;  3NVY B;  5D79 A;  3NRZ B;  3EUB 3;  4PVJ A;  3FW7 A;  2UUV A;  2YVS A;  2E3T A;  2UUU A;  1N60 C;  5AE1 A;  1W1J A;  1N61 C;  1W1Q A;  3NS1 B;  1FO4 A;  2QPM A;  2Q4W A;  3DED A;  5I1W A;  4BBY A;  5AE2 A;  2RK5 A;  1HSK A;  3S1C A;  1WVE A;  2WDW A;  2VFR A;  4BC9 A;  1W1S A;  3TSJ A;  2P4P A;  2BVG A;  4BC7 A;  2O3G A;  5ADZ A;  1W1R A;  4HG0 A;  3LLB A;  1UXY A;  3NVV B;  2IPI A;  1E8H A;  1W1O A;  5AE3 A;  3D2D A;  1V97 A;  2P3H A;  1JRO A;  4EC3 A;  3BW7 A;  3D2J A;  2Y08 A;  4PWB A;  5I1V A;  1W1M A;  5HQX A;  3D2H A;  1I19 A;  3HSU A;  3TX1 A;  1FFU C;  3NVZ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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