1W1JA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: the505ser mutant
Total Genus 178
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
178
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRSHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
source organism Penicillium simplicissimum
molecule tags Oxidoreductase
total genus 178
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1jA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1jA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1jA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1jA03
4ML8A 2PLSA 1DZNA 2MBRA 1T3QC 1W1JA 4PYTA 3C0PA 2VFUA 1JRPA 3DEDA 1W1QA 4EC3A 3ETRB 2W54A 2BVHA 5G5HB 1HSKA 1WVEA 3TSHA 4PVEA 5HHZA 5FXFA 5AE3A 2Q85A 3KJMA 2OAIA 2P4PA 1WVFA 2GQUA 1W1MA 4JAYA 1FO4A 4PWBA 1N5XA 3PM9A 4DNSA 2P13A 1N62C 2VFRA 4ZOHB 3HRDC 3TSJA 2R8DA 4BC9A 3NRZB 1RM6B 1WYGA 1E8HA 1E0YA 4BC7A 3AMZA 2QPMA 2VFVA 1VAOA 1MBBA 3JS8A 3LAEA 2O3GA 2W3SA 2W3RA 1W1OA 2EXRA 1UXYA 5HQXA 1QLUA 5ADZA 3FWAA 4HG0A 3I99A 1FIQB 3FW7A 3AM9A 3SR6B 3NVVB 4JB1A 4UD8A 3S1DA 1FFVC 3NS1B 4PZFA 1W1SA 4PVJA 5D79A 5FXPA 4PWCA 1VDVA 4PVHA 2Q4WA 4MLAA 1N61C 2QKNA 1V97A 3FW8A 3B9JB 3VTEA 3S1CA 2RK5A 2NQWA 3EUB3 1N63C 3FW9A 2VAOA 1N60C 1DIQA 3D2HA 1F0XA 2VFSA 1W1RA 2BVFA 4O95A 1MBTA 3NVZB 3LLBA 1I19A 1ZR6A 1W1LA 2PLIA 3BW7A 5FXEA 3TX1A 5G5GB 1E8GA 3D2JA 1FFUC 2E3TA 3NVYB 5HMRA 1N5WC 4PVKA 2AXRA 1JROA 2W55A 1QLTA 1ZXIC 3DQ0A 2YVSA 2BVGA 2I0KA 3S1EA 4BBYA 1W1KA 5AE2A 2R2ZA 5AE1A 1AHVA 1DIIA 1SB3B 5FXDA 3S1FA 2VFTA 3W8ZA 1AHUA 1E8FA 3W8XA 4XLOA 3GSYA 2P3HA 4BCAA 3W8WA 1AHZA 3NVWB 3AN1A 2GQTA 3D2DA 4OALA
chains in the Genus database with same CATH superfamily
4ML8A 2PLSA 1DZNA 2MBRA 1T3QC 1W1JA 4PYTA 3C0PA 2VFUA 5K8EA 1JRPA 3DEDA 1W1QA 3EJEB 4EC3A 5L6GA 3ETRB 2W54A 2BVHA 5G5HB 1HSKA 1WVEA 3TSHA 4PVEA 5HHZA 5FXFA 3HSUA 5I1WA 5AE3A 2Q85A 3KJMA 2OAIA 2P4PA 1WVFA 2GQUA 1W1MA 4JAYA 1FO4A 4PWBA 1N5XA 3PM9A 4DNSA 2P13A 1N62C 2VFRA 3POPA 4ZOHB 2Y3RA 3TSJA 3HRDC 2R8DA 4BC9A 3NRZB 1RM6B 1WYGA 1E8HA 1E0YA 4BC7A 3AMZA 2QPMA 2VFVA 1VAOA 1MBBA 3JS8A 3LAEA 3RJ8A 2O3GA 2W3SA 2W3RA 1W1OA 2EXRA 1UXYA 5HQXA 1QLUA 5ADZA 3FWAA 4HG0A 3I99A 1FIQB 2UUVA 3FW7A 3AM9A 3SR6B 3NVVB 4JB1A 4UD8A 3S1DA 1FFVC 3NS1B 4PZFA 1W1SA 4PVJA 5D79A 5FXPA 4PWCA 1VDVA 4PVHA 2Q4WA 4MLAA 1N61C 2QKNA 3PQBA 1V97A 2Y4GA 3FW8A 5L6FA 3B9JB 3VTEA 3S1CA 2RK5A 2NQWA 3EUB3 1N63C 3FW9A 2VAOA 1N60C 1DIQA 3D2HA 1F0XA 2VFSA 1W1RA 2BVFA 4O95A 1MBTA 3NVZB 3LLBA 2WDWA 1I19A 5AWVA 1ZR6A 1W1LA 2PLIA 3EJDB 3BW7A 5FXEA 3TX1A 5G5GB 2Y08A 1E8GA 3D2JA 1FFUC 2E3TA 3NVYB 5HMRA 1N5WC 4PVKA 2IPIA 2AXRA 3EJBB 1JROA 2W55A 2Y3SA 1QLTA 1ZXIC 3DQ0A 2YVSA 2BVGA 2I0KA 3S1EA 4BBYA 1W1KA 5AE2A 2R2ZA 5AE1A 1AHVA 1DIIA 1SB3B 5FXDA 3S1FA 2VFTA 3W8ZA 1AHUA 1E8FA 3W8XA 4XLOA 3GSYA 2P3HA 5I1VA 4BCAA 3W8WA 3RJAA 1AHZA 3NVWB 3AN1A 2GQTA 2UUUA 3D2DA 4OALA
chains in the Genus database with same CATH topology
4ML8A 2PLSA 1DZNA 2MBRA 1T3QC 1W1JA 4PYTA 3C0PA 2VFUA 5K8EA 1JRPA 3DEDA 1W1QA 4EC3A 5L6GA 3ETRB 2W54A 2BVHA 5G5HB 1HSKA 1WVEA 3TSHA 4PVEA 5HHZA 5FXFA 3HSUA 5I1WA 5AE3A 2Q85A 3KJMA 2OAIA 2P4PA 1WVFA 2GQUA 1W1MA 4JAYA 1FO4A 4PWBA 1N5XA 3PM9A 4DNSA 2P13A 1N62C 2VFRA 3POPA 4ZOHB 2Y3RA 3TSJA 3HRDC 2R8DA 4BC9A 3NRZB 1RM6B 1WYGA 1E8HA 1E0YA 4BC7A 3AMZA 2QPMA 2VFVA 1VAOA 1MBBA 3JS8A 3LAEA 3RJ8A 2O3GA 2W3SA 2W3RA 1W1OA 2EXRA 1UXYA 5HQXA 1QLUA 5ADZA 3FWAA 4HG0A 3I99A 1FIQB 2UUVA 3FW7A 3AM9A 3SR6B 3NVVB 4JB1A 4UD8A 3S1DA 1FFVC 3NS1B 4PZFA 1W1SA 4PVJA 5D79A 5FXPA 4PWCA 1VDVA 4PVHA 2Q4WA 4MLAA 1N61C 2QKNA 3PQBA 1V97A 2Y4GA 3FW8A 5L6FA 3B9JB 3VTEA 3S1CA 2RK5A 2NQWA 3EUB3 1N63C 3FW9A 2VAOA 1N60C 1DIQA 3D2HA 1F0XA 2VFSA 1W1RA 2BVFA 4O95A 1MBTA 3NVZB 3LLBA 2WDWA 1I19A 5AWVA 1ZR6A 1W1LA 2PLIA 3BW7A 5FXEA 3TX1A 5G5GB 2Y08A 1E8GA 3D2JA 1FFUC 2E3TA 3NVYB 5HMRA 1N5WC 4PVKA 2IPIA 2AXRA 1JROA 2W55A 2Y3SA 1QLTA 1ZXIC 3DQ0A 2YVSA 2BVGA 2I0KA 3S1EA 4BBYA 1W1KA 5AE2A 2R2ZA 5AE1A 1AHVA 1DIIA 1SB3B 5FXDA 3S1FA 2VFTA 3W8ZA 1AHUA 1E8FA 3W8XA 4XLOA 3GSYA 2P3HA 5I1VA 4BCAA 3W8WA 3RJAA 1AHZA 3NVWB 3AN1A 2GQTA 2UUUA 3D2DA 4OALA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ML8 A;  2PLS A;  1DZN A;  2MBR A;  1T3Q C;  1W1J A;  4PYT A;  3C0P A;  2VFU A;  1JRP A;  3DED A;  1W1Q A;  4EC3 A;  3ETR B;  2W54 A;  2BVH A;  5G5H B;  1HSK A;  1WVE A;  3TSH A;  4PVE A;  5HHZ A;  5FXF A;  5AE3 A;  2Q85 A;  3KJM A;  2OAI A;  2P4P A;  1WVF A;  2GQU A;  1W1M A;  4JAY A;  1FO4 A;  4PWB A;  1N5X A;  3PM9 A;  4DNS A;  2P13 A;  1N62 C;  2VFR A;  4ZOH B;  3HRD C;  3TSJ A;  2R8D A;  4BC9 A;  3NRZ B;  1RM6 B;  1WYG A;  1E8H A;  1E0Y A;  4BC7 A;  3AMZ A;  2QPM A;  2VFV A;  1VAO A;  1MBB A;  3JS8 A;  3LAE A;  2O3G A;  2W3S A;  2W3R A;  1W1O A;  2EXR A;  1UXY A;  5HQX A;  1QLU A;  5ADZ A;  3FWA A;  4HG0 A;  3I99 A;  1FIQ B;  3FW7 A;  3AM9 A;  3SR6 B;  3NVV B;  4JB1 A;  4UD8 A;  3S1D A;  1FFV C;  3NS1 B;  4PZF A;  1W1S A;  4PVJ A;  5D79 A;  5FXP A;  4PWC A;  1VDV A;  4PVH A;  2Q4W A;  4MLA A;  1N61 C;  2QKN A;  1V97 A;  3FW8 A;  3B9J B;  3VTE A;  3S1C A;  2RK5 A;  2NQW A;  3EUB 3;  1N63 C;  3FW9 A;  2VAO A;  1N60 C;  1DIQ A;  3D2H A;  1F0X A;  2VFS A;  1W1R A;  2BVF A;  4O95 A;  1MBT A;  3NVZ B;  3LLB A;  1I19 A;  1ZR6 A;  1W1L A;  2PLI A;  3BW7 A;  5FXE A;  3TX1 A;  5G5G B;  1E8G A;  3D2J A;  1FFU C;  2E3T A;  3NVY B;  5HMR A;  1N5W C;  4PVK A;  2AXR A;  1JRO A;  2W55 A;  1QLT A;  1ZXI C;  3DQ0 A;  2YVS A;  2BVG A;  2I0K A;  3S1E A;  4BBY A;  1W1K A;  5AE2 A;  2R2Z A;  5AE1 A;  1AHV A;  1DII A;  1SB3 B;  5FXD A;  3S1F A;  2VFT A;  3W8Z A;  1AHU A;  1E8F A;  3W8X A;  4XLO A;  3GSY A;  2P3H A;  4BCA A;  3W8W A;  1AHZ A;  3NVW B;  3AN1 A;  2GQT A;  3D2D A;  4OAL A; 
#chains in the Genus database with same CATH topology
 4ML8 A;  2PLS A;  1DZN A;  2MBR A;  1T3Q C;  1W1J A;  4PYT A;  3C0P A;  2VFU A;  5K8E A;  1JRP A;  3DED A;  1W1Q A;  3EJE B;  4EC3 A;  5L6G A;  3ETR B;  2W54 A;  2BVH A;  5G5H B;  1HSK A;  1WVE A;  3TSH A;  4PVE A;  5HHZ A;  5FXF A;  3HSU A;  5I1W A;  5AE3 A;  2Q85 A;  3KJM A;  2OAI A;  2P4P A;  1WVF A;  2GQU A;  1W1M A;  4JAY A;  1FO4 A;  4PWB A;  1N5X A;  3PM9 A;  4DNS A;  2P13 A;  1N62 C;  2VFR A;  3POP A;  4ZOH B;  2Y3R A;  3TSJ A;  3HRD C;  2R8D A;  4BC9 A;  3NRZ B;  1RM6 B;  1WYG A;  1E8H A;  1E0Y A;  4BC7 A;  3AMZ A;  2QPM A;  2VFV A;  1VAO A;  1MBB A;  3JS8 A;  3LAE A;  3RJ8 A;  2O3G A;  2W3S A;  2W3R A;  1W1O A;  2EXR A;  1UXY A;  5HQX A;  1QLU A;  5ADZ A;  3FWA A;  4HG0 A;  3I99 A;  1FIQ B;  2UUV A;  3FW7 A;  3AM9 A;  3SR6 B;  3NVV B;  4JB1 A;  4UD8 A;  3S1D A;  1FFV C;  3NS1 B;  4PZF A;  1W1S A;  4PVJ A;  5D79 A;  5FXP A;  4PWC A;  1VDV A;  4PVH A;  2Q4W A;  4MLA A;  1N61 C;  2QKN A;  3PQB A;  1V97 A;  2Y4G A;  3FW8 A;  5L6F A;  3B9J B;  3VTE A;  3S1C A;  2RK5 A;  2NQW A;  3EUB 3;  1N63 C;  3FW9 A;  2VAO A;  1N60 C;  1DIQ A;  3D2H A;  1F0X A;  2VFS A;  1W1R A;  2BVF A;  4O95 A;  1MBT A;  3NVZ B;  3LLB A;  2WDW A;  1I19 A;  5AWV A;  1ZR6 A;  1W1L A;  2PLI A;  3EJD B;  3BW7 A;  5FXE A;  3TX1 A;  5G5G B;  2Y08 A;  1E8G A;  3D2J A;  1FFU C;  2E3T A;  3NVY B;  5HMR A;  1N5W C;  4PVK A;  2IPI A;  2AXR A;  3EJB B;  1JRO A;  2W55 A;  2Y3S A;  1QLT A;  1ZXI C;  3DQ0 A;  2YVS A;  2BVG A;  2I0K A;  3S1E A;  4BBY A;  1W1K A;  5AE2 A;  2R2Z A;  5AE1 A;  1AHV A;  1DII A;  1SB3 B;  5FXD A;  3S1F A;  2VFT A;  3W8Z A;  1AHU A;  1E8F A;  3W8X A;  4XLO A;  3GSY A;  2P3H A;  5I1V A;  4BCA A;  3W8W A;  3RJA A;  1AHZ A;  3NVW B;  3AN1 A;  2GQT A;  2UUU A;  3D2D A;  4OAL A; 
#chains in the Genus database with same CATH homology
 4ML8 A;  2PLS A;  1DZN A;  2MBR A;  1T3Q C;  1W1J A;  4PYT A;  3C0P A;  2VFU A;  5K8E A;  1JRP A;  3DED A;  1W1Q A;  4EC3 A;  5L6G A;  3ETR B;  2W54 A;  2BVH A;  5G5H B;  1HSK A;  1WVE A;  3TSH A;  4PVE A;  5HHZ A;  5FXF A;  3HSU A;  5I1W A;  5AE3 A;  2Q85 A;  3KJM A;  2OAI A;  2P4P A;  1WVF A;  2GQU A;  1W1M A;  4JAY A;  1FO4 A;  4PWB A;  1N5X A;  3PM9 A;  4DNS A;  2P13 A;  1N62 C;  2VFR A;  3POP A;  4ZOH B;  2Y3R A;  3TSJ A;  3HRD C;  2R8D A;  4BC9 A;  3NRZ B;  1RM6 B;  1WYG A;  1E8H A;  1E0Y A;  4BC7 A;  3AMZ A;  2QPM A;  2VFV A;  1VAO A;  1MBB A;  3JS8 A;  3LAE A;  3RJ8 A;  2O3G A;  2W3S A;  2W3R A;  1W1O A;  2EXR A;  1UXY A;  5HQX A;  1QLU A;  5ADZ A;  3FWA A;  4HG0 A;  3I99 A;  1FIQ B;  2UUV A;  3FW7 A;  3AM9 A;  3SR6 B;  3NVV B;  4JB1 A;  4UD8 A;  3S1D A;  1FFV C;  3NS1 B;  4PZF A;  1W1S A;  4PVJ A;  5D79 A;  5FXP A;  4PWC A;  1VDV A;  4PVH A;  2Q4W A;  4MLA A;  1N61 C;  2QKN A;  3PQB A;  1V97 A;  2Y4G A;  3FW8 A;  5L6F A;  3B9J B;  3VTE A;  3S1C A;  2RK5 A;  2NQW A;  3EUB 3;  1N63 C;  3FW9 A;  2VAO A;  1N60 C;  1DIQ A;  3D2H A;  1F0X A;  2VFS A;  1W1R A;  2BVF A;  4O95 A;  1MBT A;  3NVZ B;  3LLB A;  2WDW A;  1I19 A;  5AWV A;  1ZR6 A;  1W1L A;  2PLI A;  3BW7 A;  5FXE A;  3TX1 A;  5G5G B;  2Y08 A;  1E8G A;  3D2J A;  1FFU C;  2E3T A;  3NVY B;  5HMR A;  1N5W C;  4PVK A;  2IPI A;  2AXR A;  1JRO A;  2W55 A;  2Y3S A;  1QLT A;  1ZXI C;  3DQ0 A;  2YVS A;  2BVG A;  2I0K A;  3S1E A;  4BBY A;  1W1K A;  5AE2 A;  2R2Z A;  5AE1 A;  1AHV A;  1DII A;  1SB3 B;  5FXD A;  3S1F A;  2VFT A;  3W8Z A;  1AHU A;  1E8F A;  3W8X A;  4XLO A;  3GSY A;  2P3H A;  5I1V A;  4BCA A;  3W8W A;  3RJA A;  1AHZ A;  3NVW B;  3AN1 A;  2GQT A;  2UUU A;  3D2D A;  4OAL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...