3W8XA

The complex structure of encm with trifluorotriketide
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
461
structure length
461
Chain Sequence
QFPQLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARCTSTPDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIKVSRRLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFGWLSRKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVVTAFEFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLRLAPPLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKATLPYRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPFTQLELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWAREGYRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTNLFRLNQNIPPS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Putative FAD-dependent oxygenase EncM
publication title Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
pubmed doi rcsb
source organism Streptomyces maritimus
molecule tags Oxidoreductase
total genus 137
structure length 461
sequence length 461
chains with identical sequence B
ec nomenclature ec 1.13.12.-:
pdb deposition date 2013-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3w8xA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3w8xA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3w8xA03
2W54A 1AHUA 1VAOA 1MBTA 2R8DA 5G5HB 4MLAA 2W3SA 3AMZA 5AE1A 3S1CA 5L6FA 4UD8A 3NVZB 5HQXA 5I1VA 2NQWA 3RJAA 2P13A 1W1SA 3RJ8A 4BCAA 1T3QC 1JROA 3PM9A 2RK5A 1W1LA 3PQBA 1N62C 2VAOA 2W3RA 3D2HA 1QLUA 3TSJA 5HHZA 1MBBA 3S1DA 3HRDC 4JAYA 1E0YA 3D2JA 3TX1A 2YVSA 1AHVA 1N5WC 2E3TA 4BC9A 2AXRA 3EUB3 2Y3SA 1N63C 3FW9A 1ZR6A 4PWBA 3SR6B 1FFVC 1W1RA 2P4PA 4HG0A 1N61C 1F0XA 3POPA 3I99A 4PVKA 3W8ZA 5ADZA 3DEDA 3FW7A 1FFUC 4O95A 2VFTA 3VTEA 3DQ0A 1E8GA 5AE3A 1V97A 3KJMA 2WDWA 3B9JB 4PYTA 3LAEA 3HSUA 1W1JA 3NS1B 2PLIA 2Y3RA 5FXEA 4ML8A 1WVEA 5FXFA 2VFVA 1N60C 1JRPA 3W8WA 5K8EA 4ZOHB 2OAIA 4DNSA 3W8XA 4OALA 5I1WA 1QLTA 2BVFA 3NVWB 1AHZA 1FIQB 3GSYA 2R2ZA 3TSHA 1DIQA 3FW8A 5FXPA 4XLOA 2P3HA 3D2DA 4PVJA 2Q4WA 1W1MA 1VDVA 2VFSA 3ETRB 5FXDA 1I19A 4JB1A 3LLBA 3NVYB 2QKNA 4PWCA 3FWAA 2BVGA 2QPMA 2Y4GA 4PZFA 1WVFA 3NRZB 1SB3B 5L6GA 1W1OA 3AN1A 1WYGA 2VFRA 1W1QA 5HMRA 1N5XA 3JS8A 3S1EA 3NVVB 1FO4A 2EXRA 5G5GB 3BW7A 4BC7A 1UXYA 2Y08A 2I0KA 2BVHA 3S1FA 2O3GA 2IPIA 5AE2A 4EC3A 2GQUA 4PVHA 1RM6B 1E8FA 2PLSA 4BBYA 2GQTA 3AM9A 1HSKA 5D79A 2Q85A 1DZNA 2VFUA 1W1KA 3C0PA 1ZXIC 2MBRA 4PVEA 5AWVA 1E8HA 2W55A 1DIIA
chains in the Genus database with same CATH superfamily
2W54A 1AHUA 2UUUA 1VAOA 1MBTA 2R8DA 5G5HB 4MLAA 2W3SA 3AMZA 5AE1A 3S1CA 5L6FA 4UD8A 3NVZB 5HQXA 5I1VA 2NQWA 3RJAA 2P13A 1W1SA 3RJ8A 4BCAA 1T3QC 1JROA 3PM9A 2RK5A 1W1LA 3PQBA 1N62C 2VAOA 2W3RA 3D2HA 1QLUA 3TSJA 5HHZA 1MBBA 3S1DA 3HRDC 4JAYA 1E0YA 3D2JA 3TX1A 2YVSA 1AHVA 1N5WC 2E3TA 4BC9A 2AXRA 3EUB3 2Y3SA 1N63C 3FW9A 1ZR6A 4PWBA 3SR6B 1FFVC 1W1RA 2P4PA 4HG0A 1N61C 1F0XA 3POPA 3I99A 4PVKA 3W8ZA 5ADZA 3DEDA 3FW7A 1FFUC 4O95A 2VFTA 3VTEA 3DQ0A 1E8GA 5AE3A 1V97A 3KJMA 2WDWA 3B9JB 4PYTA 3HSUA 3LAEA 1W1JA 3NS1B 2PLIA 2Y3RA 5FXEA 4ML8A 1WVEA 3EJDB 2VFVA 1N60C 5FXFA 1JRPA 3W8WA 5K8EA 4ZOHB 2OAIA 4DNSA 3W8XA 4OALA 5I1WA 1QLTA 2BVFA 3NVWB 1AHZA 1FIQB 3GSYA 2R2ZA 3TSHA 1DIQA 3FW8A 5FXPA 4XLOA 2P3HA 3D2DA 4PVJA 2Q4WA 1W1MA 1VDVA 2VFSA 3ETRB 5FXDA 1I19A 3EJEB 4JB1A 3NVYB 3LLBA 2QKNA 4PWCA 3FWAA 2BVGA 2QPMA 2Y4GA 4PZFA 1WVFA 3NRZB 1SB3B 5L6GA 1W1OA 3AN1A 1WYGA 2VFRA 1W1QA 5HMRA 2UUVA 1N5XA 3JS8A 3S1EA 3NVVB 1FO4A 2EXRA 5G5GB 3BW7A 4BC7A 1UXYA 2Y08A 2I0KA 2BVHA 3S1FA 2O3GA 2IPIA 5AE2A 4EC3A 2GQUA 4PVHA 3EJBB 1RM6B 1E8FA 2PLSA 4BBYA 2GQTA 3AM9A 1HSKA 5D79A 2Q85A 1DZNA 2VFUA 1W1KA 3C0PA 1ZXIC 2MBRA 4PVEA 5AWVA 1E8HA 2W55A 1DIIA
chains in the Genus database with same CATH topology
2W54A 1AHUA 2UUUA 1VAOA 1MBTA 2R8DA 5G5HB 4MLAA 2W3SA 3AMZA 5AE1A 3S1CA 5L6FA 4UD8A 3NVZB 5HQXA 5I1VA 2NQWA 3RJAA 2P13A 1W1SA 3RJ8A 4BCAA 1T3QC 1JROA 3PM9A 2RK5A 1W1LA 3PQBA 1N62C 2VAOA 2W3RA 3D2HA 1QLUA 3TSJA 5HHZA 1MBBA 3S1DA 3HRDC 4JAYA 1E0YA 3D2JA 3TX1A 2YVSA 1AHVA 1N5WC 2E3TA 4BC9A 2AXRA 3EUB3 2Y3SA 1N63C 3FW9A 1ZR6A 4PWBA 3SR6B 1FFVC 1W1RA 2P4PA 4HG0A 1N61C 1F0XA 3POPA 3I99A 4PVKA 3W8ZA 5ADZA 3DEDA 3FW7A 1FFUC 4O95A 2VFTA 3VTEA 3DQ0A 1E8GA 5AE3A 1V97A 3KJMA 2WDWA 3B9JB 4PYTA 3HSUA 3LAEA 1W1JA 3NS1B 2PLIA 2Y3RA 5FXEA 4ML8A 1WVEA 5FXFA 2VFVA 1N60C 1JRPA 3W8WA 5K8EA 4ZOHB 2OAIA 4DNSA 3W8XA 4OALA 5I1WA 1QLTA 2BVFA 3NVWB 1AHZA 1FIQB 3GSYA 2R2ZA 3TSHA 1DIQA 3FW8A 5FXPA 4XLOA 2P3HA 3D2DA 4PVJA 2Q4WA 1W1MA 1VDVA 2VFSA 3ETRB 5FXDA 1I19A 4JB1A 3LLBA 3NVYB 2QKNA 4PWCA 3FWAA 2BVGA 2QPMA 2Y4GA 4PZFA 1WVFA 3NRZB 1SB3B 5L6GA 1W1OA 3AN1A 1WYGA 2VFRA 1W1QA 5HMRA 2UUVA 1N5XA 3JS8A 3S1EA 3NVVB 1FO4A 2EXRA 5G5GB 3BW7A 4BC7A 1UXYA 2Y08A 2I0KA 2BVHA 3S1FA 2O3GA 2IPIA 5AE2A 4EC3A 2GQUA 4PVHA 1RM6B 1E8FA 2PLSA 4BBYA 2GQTA 3AM9A 1HSKA 5D79A 2Q85A 1DZNA 2VFUA 1W1KA 3C0PA 1ZXIC 2MBRA 4PVEA 5AWVA 1E8HA 2W55A 1DIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W54 A;  1AHU A;  1VAO A;  1MBT A;  2R8D A;  5G5H B;  4MLA A;  2W3S A;  3AMZ A;  5AE1 A;  3S1C A;  5L6F A;  4UD8 A;  3NVZ B;  5HQX A;  5I1V A;  2NQW A;  3RJA A;  2P13 A;  1W1S A;  3RJ8 A;  4BCA A;  1T3Q C;  1JRO A;  3PM9 A;  2RK5 A;  1W1L A;  3PQB A;  1N62 C;  2VAO A;  2W3R A;  3D2H A;  1QLU A;  3TSJ A;  5HHZ A;  1MBB A;  3S1D A;  3HRD C;  4JAY A;  1E0Y A;  3D2J A;  3TX1 A;  2YVS A;  1AHV A;  1N5W C;  2E3T A;  4BC9 A;  2AXR A;  3EUB 3;  2Y3S A;  1N63 C;  3FW9 A;  1ZR6 A;  4PWB A;  3SR6 B;  1FFV C;  1W1R A;  2P4P A;  4HG0 A;  1N61 C;  1F0X A;  3POP A;  3I99 A;  4PVK A;  3W8Z A;  5ADZ A;  3DED A;  3FW7 A;  1FFU C;  4O95 A;  2VFT A;  3VTE A;  3DQ0 A;  1E8G A;  5AE3 A;  1V97 A;  3KJM A;  2WDW A;  3B9J B;  4PYT A;  3LAE A;  3HSU A;  1W1J A;  3NS1 B;  2PLI A;  2Y3R A;  5FXE A;  4ML8 A;  1WVE A;  5FXF A;  2VFV A;  1N60 C;  1JRP A;  3W8W A;  5K8E A;  4ZOH B;  2OAI A;  4DNS A;  3W8X A;  4OAL A;  5I1W A;  1QLT A;  2BVF A;  3NVW B;  1AHZ A;  1FIQ B;  3GSY A;  2R2Z A;  3TSH A;  1DIQ A;  3FW8 A;  5FXP A;  4XLO A;  2P3H A;  3D2D A;  4PVJ A;  2Q4W A;  1W1M A;  1VDV A;  2VFS A;  3ETR B;  5FXD A;  1I19 A;  4JB1 A;  3LLB A;  3NVY B;  2QKN A;  4PWC A;  3FWA A;  2BVG A;  2QPM A;  2Y4G A;  4PZF A;  1WVF A;  3NRZ B;  1SB3 B;  5L6G A;  1W1O A;  3AN1 A;  1WYG A;  2VFR A;  1W1Q A;  5HMR A;  1N5X A;  3JS8 A;  3S1E A;  3NVV B;  1FO4 A;  2EXR A;  5G5G B;  3BW7 A;  4BC7 A;  1UXY A;  2Y08 A;  2I0K A;  2BVH A;  3S1F A;  2O3G A;  2IPI A;  5AE2 A;  4EC3 A;  2GQU A;  4PVH A;  1RM6 B;  1E8F A;  2PLS A;  4BBY A;  2GQT A;  3AM9 A;  1HSK A;  5D79 A;  2Q85 A;  1DZN A;  2VFU A;  1W1K A;  3C0P A;  1ZXI C;  2MBR A;  4PVE A;  5AWV A;  1E8H A;  2W55 A;  1DII A; 
#chains in the Genus database with same CATH topology
 2W54 A;  1AHU A;  2UUU A;  1VAO A;  1MBT A;  2R8D A;  5G5H B;  4MLA A;  2W3S A;  3AMZ A;  5AE1 A;  3S1C A;  5L6F A;  4UD8 A;  3NVZ B;  5HQX A;  5I1V A;  2NQW A;  3RJA A;  2P13 A;  1W1S A;  3RJ8 A;  4BCA A;  1T3Q C;  1JRO A;  3PM9 A;  2RK5 A;  1W1L A;  3PQB A;  1N62 C;  2VAO A;  2W3R A;  3D2H A;  1QLU A;  3TSJ A;  5HHZ A;  1MBB A;  3S1D A;  3HRD C;  4JAY A;  1E0Y A;  3D2J A;  3TX1 A;  2YVS A;  1AHV A;  1N5W C;  2E3T A;  4BC9 A;  2AXR A;  3EUB 3;  2Y3S A;  1N63 C;  3FW9 A;  1ZR6 A;  4PWB A;  3SR6 B;  1FFV C;  1W1R A;  2P4P A;  4HG0 A;  1N61 C;  1F0X A;  3POP A;  3I99 A;  4PVK A;  3W8Z A;  5ADZ A;  3DED A;  3FW7 A;  1FFU C;  4O95 A;  2VFT A;  3VTE A;  3DQ0 A;  1E8G A;  5AE3 A;  1V97 A;  3KJM A;  2WDW A;  3B9J B;  4PYT A;  3HSU A;  3LAE A;  1W1J A;  3NS1 B;  2PLI A;  2Y3R A;  5FXE A;  4ML8 A;  1WVE A;  3EJD B;  2VFV A;  1N60 C;  5FXF A;  1JRP A;  3W8W A;  5K8E A;  4ZOH B;  2OAI A;  4DNS A;  3W8X A;  4OAL A;  5I1W A;  1QLT A;  2BVF A;  3NVW B;  1AHZ A;  1FIQ B;  3GSY A;  2R2Z A;  3TSH A;  1DIQ A;  3FW8 A;  5FXP A;  4XLO A;  2P3H A;  3D2D A;  4PVJ A;  2Q4W A;  1W1M A;  1VDV A;  2VFS A;  3ETR B;  5FXD A;  1I19 A;  3EJE B;  4JB1 A;  3NVY B;  3LLB A;  2QKN A;  4PWC A;  3FWA A;  2BVG A;  2QPM A;  2Y4G A;  4PZF A;  1WVF A;  3NRZ B;  1SB3 B;  5L6G A;  1W1O A;  3AN1 A;  1WYG A;  2VFR A;  1W1Q A;  5HMR A;  2UUV A;  1N5X A;  3JS8 A;  3S1E A;  3NVV B;  1FO4 A;  2EXR A;  5G5G B;  3BW7 A;  4BC7 A;  1UXY A;  2Y08 A;  2I0K A;  2BVH A;  3S1F A;  2O3G A;  2IPI A;  5AE2 A;  4EC3 A;  2GQU A;  4PVH A;  3EJB B;  1RM6 B;  1E8F A;  2PLS A;  4BBY A;  2GQT A;  3AM9 A;  1HSK A;  5D79 A;  2Q85 A;  1DZN A;  2VFU A;  1W1K A;  3C0P A;  1ZXI C;  2MBR A;  4PVE A;  5AWV A;  1E8H A;  2W55 A;  1DII A; 
#chains in the Genus database with same CATH homology
 2W54 A;  1AHU A;  2UUU A;  1VAO A;  1MBT A;  2R8D A;  5G5H B;  4MLA A;  2W3S A;  3AMZ A;  5AE1 A;  3S1C A;  5L6F A;  4UD8 A;  3NVZ B;  5HQX A;  5I1V A;  2NQW A;  3RJA A;  2P13 A;  1W1S A;  3RJ8 A;  4BCA A;  1T3Q C;  1JRO A;  3PM9 A;  2RK5 A;  1W1L A;  3PQB A;  1N62 C;  2VAO A;  2W3R A;  3D2H A;  1QLU A;  3TSJ A;  5HHZ A;  1MBB A;  3S1D A;  3HRD C;  4JAY A;  1E0Y A;  3D2J A;  3TX1 A;  2YVS A;  1AHV A;  1N5W C;  2E3T A;  4BC9 A;  2AXR A;  3EUB 3;  2Y3S A;  1N63 C;  3FW9 A;  1ZR6 A;  4PWB A;  3SR6 B;  1FFV C;  1W1R A;  2P4P A;  4HG0 A;  1N61 C;  1F0X A;  3POP A;  3I99 A;  4PVK A;  3W8Z A;  5ADZ A;  3DED A;  3FW7 A;  1FFU C;  4O95 A;  2VFT A;  3VTE A;  3DQ0 A;  1E8G A;  5AE3 A;  1V97 A;  3KJM A;  2WDW A;  3B9J B;  4PYT A;  3HSU A;  3LAE A;  1W1J A;  3NS1 B;  2PLI A;  2Y3R A;  5FXE A;  4ML8 A;  1WVE A;  5FXF A;  2VFV A;  1N60 C;  1JRP A;  3W8W A;  5K8E A;  4ZOH B;  2OAI A;  4DNS A;  3W8X A;  4OAL A;  5I1W A;  1QLT A;  2BVF A;  3NVW B;  1AHZ A;  1FIQ B;  3GSY A;  2R2Z A;  3TSH A;  1DIQ A;  3FW8 A;  5FXP A;  4XLO A;  2P3H A;  3D2D A;  4PVJ A;  2Q4W A;  1W1M A;  1VDV A;  2VFS A;  3ETR B;  5FXD A;  1I19 A;  4JB1 A;  3LLB A;  3NVY B;  2QKN A;  4PWC A;  3FWA A;  2BVG A;  2QPM A;  2Y4G A;  4PZF A;  1WVF A;  3NRZ B;  1SB3 B;  5L6G A;  1W1O A;  3AN1 A;  1WYG A;  2VFR A;  1W1Q A;  5HMR A;  2UUV A;  1N5X A;  3JS8 A;  3S1E A;  3NVV B;  1FO4 A;  2EXR A;  5G5G B;  3BW7 A;  4BC7 A;  1UXY A;  2Y08 A;  2I0K A;  2BVH A;  3S1F A;  2O3G A;  2IPI A;  5AE2 A;  4EC3 A;  2GQU A;  4PVH A;  1RM6 B;  1E8F A;  2PLS A;  4BBY A;  2GQT A;  3AM9 A;  1HSK A;  5D79 A;  2Q85 A;  1DZN A;  2VFU A;  1W1K A;  3C0P A;  1ZXI C;  2MBR A;  4PVE A;  5AWV A;  1E8H A;  2W55 A;  1DII A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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