4JB1A

Crystal structure of p. aeruginosa murb in complex with nadp+
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
337
structure length
337
Chain Sequence
LELQEHCSLKPYNTFGIDVRARLLAHARDEADVREALALARERGLPLLVIGGGSNLLLTRDVEALVLRMASQGRRIVSDAADSVLVEAEAGEAWDPFVQWSLERGLAGLENLSLIPGTVGAAPMQNIGAYGVELKDVFDSLTALDRQDGTLREFDRQACRFGYRDSLFKQEPDRWLILRVRLRLTRRERLHLDYGPVRQRLEEEGIASPTARDVSRVICAIRREKLPDPAVLGNAGSFFKNPLVDATQAERLRQAFPDLVGYPQADGRLKLAAGWLIDKGGWKGFRDGPVGVHAQQALVLVNHGGATGAQVRALAERIQEDVRRRFGVELEPEPNLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Oxidoreductase
molecule keywords UDP-N-acetylenolpyruvoylglucosamine reductase
total genus 109
structure length 337
sequence length 337
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2013-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4jb1A01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4jb1A02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 4jb1A03
5AE1A 3DQ0A 3NVZB 2W3RA 1RM6B 3D2HA 2EXRA 1AHVA 4PVEA 2OAIA 1ZXIC 2BVHA 2RK5A 2P3HA 1QLUA 1N5XA 2GQUA 3BW7A 3FW8A 1ZR6A 3S1CA 3W8ZA 3NVVB 2P4PA 1N62C 3NVWB 4PZFA 1FFUC 2VAOA 1W1KA 4PWCA 5FXEA 1AHZA 3DEDA 3FWAA 1FFVC 1FIQB 2I0KA 3I99A 4PVKA 3LLBA 3D2JA 5HQXA 2Q85A 4BC7A 1JROA 2PLIA 1FO4A 4PVHA 1N61C 1MBBA 4BC9A 3NS1B 3NRZB 3SR6B 4EC3A 4PYTA 5HHZA 4DNSA 1MBTA 2BVFA 3GSYA 2O3GA 1N60C 1WYGA 2VFSA 2NQWA 3TSJA 3VTEA 1E0YA 3JS8A 2PLSA 1AHUA 3EUB3 1SB3B 2E3TA 3S1EA 2YVSA 5FXDA 4JAYA 3TX1A 3FW9A 2R8DA 2VFTA 1W1SA 5FXPA 1E8HA 1T3QC 5D79A 1WVFA 4PWBA 3W8XA 3W8WA 2P13A 4XLOA 2VFRA 4ZOHB 1I19A 1HSKA 3S1DA 1E8GA 2VFVA 1DZNA 2W54A 2MBRA 4UD8A 5HMRA 2R2ZA 1UXYA 3PM9A 5FXFA 3HRDC 1WVEA 4O95A 2AXRA 3AMZA 4JB1A 4PVJA 2QPMA 1QLTA 5G5HB 1JRPA 1F0XA 3AM9A 4MLAA 5AE3A 1N63C 1W1LA 2BVGA 3D2DA 2Q4WA 4ML8A 1N5WC 1V97A 1VDVA 2W55A 5G5GB 2QKNA 3NVYB 1W1JA 1DIQA 3B9JB 3TSHA 1W1QA 1DIIA 2VFUA 3KJMA 1W1MA 2W3SA 1W1OA 5ADZA 3S1FA 3ETRB 1VAOA 2GQTA 3AN1A 4OALA 5AE2A 3FW7A 4BBYA 1W1RA 4BCAA 3LAEA 4HG0A 3C0PA 1E8FA
chains in the Genus database with same CATH superfamily
5AE1A 3DQ0A 3NVZB 2W3RA 1RM6B 3D2HA 2EXRA 5L6GA 1AHVA 4PVEA 2OAIA 1ZXIC 2BVHA 2RK5A 2P3HA 1QLUA 1N5XA 2GQUA 3BW7A 3FW8A 1ZR6A 3S1CA 3W8ZA 5L6FA 3NVVB 2P4PA 1N62C 3NVWB 4PZFA 1FFUC 2VAOA 1W1KA 4PWCA 5FXEA 1AHZA 3DEDA 3PQBA 3FWAA 1FFVC 1FIQB 2I0KA 3I99A 4PVKA 3LLBA 3D2JA 5HQXA 2Q85A 4BC7A 1JROA 3EJEB 2PLIA 1FO4A 4PVHA 1N61C 3POPA 1MBBA 4BC9A 3NS1B 3NRZB 2UUUA 3SR6B 4EC3A 4PYTA 5HHZA 2Y4GA 4DNSA 3RJ8A 1MBTA 2BVFA 3GSYA 2O3GA 3RJAA 1N60C 1WYGA 2VFSA 2NQWA 3TSJA 3VTEA 1E0YA 5I1VA 3JS8A 2PLSA 1AHUA 3EUB3 1SB3B 2E3TA 3S1EA 2YVSA 5FXDA 4JAYA 3TX1A 3FW9A 2IPIA 2R8DA 2VFTA 1W1SA 5FXPA 1E8HA 1T3QC 5D79A 1WVFA 4PWBA 3W8XA 3W8WA 2P13A 4XLOA 2VFRA 4ZOHB 1I19A 1HSKA 3S1DA 1E8GA 2VFVA 1DZNA 2W54A 2MBRA 4UD8A 5HMRA 2R2ZA 1UXYA 3PM9A 5FXFA 3HRDC 1WVEA 4O95A 2AXRA 3AMZA 3EJBB 4JB1A 4PVJA 2QPMA 1QLTA 5G5HB 1JRPA 1F0XA 3AM9A 4MLAA 5AE3A 1N63C 1W1LA 2BVGA 3D2DA 2Q4WA 2UUVA 5AWVA 4ML8A 1N5WC 1V97A 1VDVA 2W55A 5G5GB 5K8EA 2QKNA 3HSUA 3NVYB 1W1JA 1DIQA 2WDWA 2Y08A 2Y3SA 3B9JB 3TSHA 1W1QA 1DIIA 2VFUA 3KJMA 1W1MA 2W3SA 1W1OA 5ADZA 3S1FA 3ETRB 1VAOA 2GQTA 3AN1A 4OALA 5I1WA 5AE2A 3FW7A 4BBYA 1W1RA 4BCAA 3EJDB 3LAEA 4HG0A 3C0PA 2Y3RA 1E8FA
chains in the Genus database with same CATH topology
5AE1A 3DQ0A 3NVZB 2W3RA 1RM6B 3D2HA 2EXRA 5L6GA 1AHVA 4PVEA 2OAIA 1ZXIC 2BVHA 2RK5A 2P3HA 1QLUA 1N5XA 2GQUA 3BW7A 3FW8A 1ZR6A 3S1CA 3W8ZA 5L6FA 3NVVB 2P4PA 1N62C 3NVWB 4PZFA 1FFUC 2VAOA 1W1KA 4PWCA 5FXEA 1AHZA 3DEDA 3PQBA 3FWAA 1FFVC 1FIQB 2I0KA 3I99A 4PVKA 3LLBA 3D2JA 5HQXA 2Q85A 4BC7A 1JROA 2PLIA 1FO4A 4PVHA 1N61C 3POPA 1MBBA 4BC9A 3NS1B 3NRZB 2UUUA 3SR6B 4EC3A 4PYTA 5HHZA 2Y4GA 4DNSA 3RJ8A 1MBTA 2BVFA 3GSYA 2O3GA 3RJAA 1N60C 1WYGA 2VFSA 2NQWA 3TSJA 3VTEA 1E0YA 5I1VA 3JS8A 2PLSA 1AHUA 3EUB3 1SB3B 2E3TA 3S1EA 2YVSA 5FXDA 4JAYA 3TX1A 3FW9A 2IPIA 2R8DA 2VFTA 1W1SA 5FXPA 1E8HA 1T3QC 5D79A 1WVFA 4PWBA 3W8XA 3W8WA 2P13A 4XLOA 2VFRA 4ZOHB 1I19A 1HSKA 3S1DA 1E8GA 2VFVA 1DZNA 2W54A 2MBRA 4UD8A 5HMRA 2R2ZA 1UXYA 3PM9A 5FXFA 3HRDC 1WVEA 4O95A 2AXRA 3AMZA 4JB1A 4PVJA 2QPMA 1QLTA 5G5HB 1JRPA 1F0XA 3AM9A 4MLAA 5AE3A 1N63C 1W1LA 2BVGA 3D2DA 2Q4WA 2UUVA 5AWVA 4ML8A 1N5WC 1V97A 1VDVA 2W55A 5G5GB 5K8EA 2QKNA 3HSUA 3NVYB 1W1JA 1DIQA 2WDWA 2Y08A 2Y3SA 3B9JB 3TSHA 1W1QA 1DIIA 2VFUA 3KJMA 1W1MA 2W3SA 1W1OA 5ADZA 3S1FA 3ETRB 1VAOA 2GQTA 3AN1A 4OALA 5I1WA 5AE2A 3FW7A 4BBYA 1W1RA 4BCAA 3LAEA 4HG0A 3C0PA 2Y3RA 1E8FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AE1 A;  3DQ0 A;  3NVZ B;  2W3R A;  1RM6 B;  3D2H A;  2EXR A;  1AHV A;  4PVE A;  2OAI A;  1ZXI C;  2BVH A;  2RK5 A;  2P3H A;  1QLU A;  1N5X A;  2GQU A;  3BW7 A;  3FW8 A;  1ZR6 A;  3S1C A;  3W8Z A;  3NVV B;  2P4P A;  1N62 C;  3NVW B;  4PZF A;  1FFU C;  2VAO A;  1W1K A;  4PWC A;  5FXE A;  1AHZ A;  3DED A;  3FWA A;  1FFV C;  1FIQ B;  2I0K A;  3I99 A;  4PVK A;  3LLB A;  3D2J A;  5HQX A;  2Q85 A;  4BC7 A;  1JRO A;  2PLI A;  1FO4 A;  4PVH A;  1N61 C;  1MBB A;  4BC9 A;  3NS1 B;  3NRZ B;  3SR6 B;  4EC3 A;  4PYT A;  5HHZ A;  4DNS A;  1MBT A;  2BVF A;  3GSY A;  2O3G A;  1N60 C;  1WYG A;  2VFS A;  2NQW A;  3TSJ A;  3VTE A;  1E0Y A;  3JS8 A;  2PLS A;  1AHU A;  3EUB 3;  1SB3 B;  2E3T A;  3S1E A;  2YVS A;  5FXD A;  4JAY A;  3TX1 A;  3FW9 A;  2R8D A;  2VFT A;  1W1S A;  5FXP A;  1E8H A;  1T3Q C;  5D79 A;  1WVF A;  4PWB A;  3W8X A;  3W8W A;  2P13 A;  4XLO A;  2VFR A;  4ZOH B;  1I19 A;  1HSK A;  3S1D A;  1E8G A;  2VFV A;  1DZN A;  2W54 A;  2MBR A;  4UD8 A;  5HMR A;  2R2Z A;  1UXY A;  3PM9 A;  5FXF A;  3HRD C;  1WVE A;  4O95 A;  2AXR A;  3AMZ A;  4JB1 A;  4PVJ A;  2QPM A;  1QLT A;  5G5H B;  1JRP A;  1F0X A;  3AM9 A;  4MLA A;  5AE3 A;  1N63 C;  1W1L A;  2BVG A;  3D2D A;  2Q4W A;  4ML8 A;  1N5W C;  1V97 A;  1VDV A;  2W55 A;  5G5G B;  2QKN A;  3NVY B;  1W1J A;  1DIQ A;  3B9J B;  3TSH A;  1W1Q A;  1DII A;  2VFU A;  3KJM A;  1W1M A;  2W3S A;  1W1O A;  5ADZ A;  3S1F A;  3ETR B;  1VAO A;  2GQT A;  3AN1 A;  4OAL A;  5AE2 A;  3FW7 A;  4BBY A;  1W1R A;  4BCA A;  3LAE A;  4HG0 A;  3C0P A;  1E8F A; 
#chains in the Genus database with same CATH topology
 5AE1 A;  3DQ0 A;  3NVZ B;  2W3R A;  1RM6 B;  3D2H A;  2EXR A;  5L6G A;  1AHV A;  4PVE A;  2OAI A;  1ZXI C;  2BVH A;  2RK5 A;  2P3H A;  1QLU A;  1N5X A;  2GQU A;  3BW7 A;  3FW8 A;  1ZR6 A;  3S1C A;  3W8Z A;  5L6F A;  3NVV B;  2P4P A;  1N62 C;  3NVW B;  4PZF A;  1FFU C;  2VAO A;  1W1K A;  4PWC A;  5FXE A;  1AHZ A;  3DED A;  3PQB A;  3FWA A;  1FFV C;  1FIQ B;  2I0K A;  3I99 A;  4PVK A;  3LLB A;  3D2J A;  5HQX A;  2Q85 A;  4BC7 A;  1JRO A;  3EJE B;  2PLI A;  1FO4 A;  4PVH A;  1N61 C;  3POP A;  1MBB A;  4BC9 A;  3NS1 B;  3NRZ B;  2UUU A;  3SR6 B;  4EC3 A;  4PYT A;  5HHZ A;  2Y4G A;  4DNS A;  3RJ8 A;  1MBT A;  2BVF A;  3GSY A;  2O3G A;  3RJA A;  1N60 C;  1WYG A;  2VFS A;  2NQW A;  3TSJ A;  3VTE A;  1E0Y A;  5I1V A;  3JS8 A;  2PLS A;  1AHU A;  3EUB 3;  1SB3 B;  2E3T A;  3S1E A;  2YVS A;  5FXD A;  4JAY A;  3TX1 A;  3FW9 A;  2IPI A;  2R8D A;  2VFT A;  1W1S A;  5FXP A;  1E8H A;  1T3Q C;  5D79 A;  1WVF A;  4PWB A;  3W8X A;  3W8W A;  2P13 A;  4XLO A;  2VFR A;  4ZOH B;  1I19 A;  1HSK A;  3S1D A;  1E8G A;  2VFV A;  1DZN A;  2W54 A;  2MBR A;  4UD8 A;  5HMR A;  2R2Z A;  1UXY A;  3PM9 A;  5FXF A;  3HRD C;  1WVE A;  4O95 A;  2AXR A;  3AMZ A;  3EJB B;  4JB1 A;  4PVJ A;  2QPM A;  1QLT A;  5G5H B;  1JRP A;  1F0X A;  3AM9 A;  4MLA A;  5AE3 A;  1N63 C;  1W1L A;  2BVG A;  3D2D A;  2Q4W A;  2UUV A;  5AWV A;  4ML8 A;  1N5W C;  1V97 A;  1VDV A;  2W55 A;  5G5G B;  5K8E A;  2QKN A;  3HSU A;  3NVY B;  1W1J A;  1DIQ A;  2WDW A;  2Y08 A;  2Y3S A;  3B9J B;  3TSH A;  1W1Q A;  1DII A;  2VFU A;  3KJM A;  1W1M A;  2W3S A;  1W1O A;  5ADZ A;  3S1F A;  3ETR B;  1VAO A;  2GQT A;  3AN1 A;  4OAL A;  5I1W A;  5AE2 A;  3FW7 A;  4BBY A;  1W1R A;  4BCA A;  3EJD B;  3LAE A;  4HG0 A;  3C0P A;  2Y3R A;  1E8F A; 
#chains in the Genus database with same CATH homology
 5AE1 A;  3DQ0 A;  3NVZ B;  2W3R A;  1RM6 B;  3D2H A;  2EXR A;  5L6G A;  1AHV A;  4PVE A;  2OAI A;  1ZXI C;  2BVH A;  2RK5 A;  2P3H A;  1QLU A;  1N5X A;  2GQU A;  3BW7 A;  3FW8 A;  1ZR6 A;  3S1C A;  3W8Z A;  5L6F A;  3NVV B;  2P4P A;  1N62 C;  3NVW B;  4PZF A;  1FFU C;  2VAO A;  1W1K A;  4PWC A;  5FXE A;  1AHZ A;  3DED A;  3PQB A;  3FWA A;  1FFV C;  1FIQ B;  2I0K A;  3I99 A;  4PVK A;  3LLB A;  3D2J A;  5HQX A;  2Q85 A;  4BC7 A;  1JRO A;  2PLI A;  1FO4 A;  4PVH A;  1N61 C;  3POP A;  1MBB A;  4BC9 A;  3NS1 B;  3NRZ B;  2UUU A;  3SR6 B;  4EC3 A;  4PYT A;  5HHZ A;  2Y4G A;  4DNS A;  3RJ8 A;  1MBT A;  2BVF A;  3GSY A;  2O3G A;  3RJA A;  1N60 C;  1WYG A;  2VFS A;  2NQW A;  3TSJ A;  3VTE A;  1E0Y A;  5I1V A;  3JS8 A;  2PLS A;  1AHU A;  3EUB 3;  1SB3 B;  2E3T A;  3S1E A;  2YVS A;  5FXD A;  4JAY A;  3TX1 A;  3FW9 A;  2IPI A;  2R8D A;  2VFT A;  1W1S A;  5FXP A;  1E8H A;  1T3Q C;  5D79 A;  1WVF A;  4PWB A;  3W8X A;  3W8W A;  2P13 A;  4XLO A;  2VFR A;  4ZOH B;  1I19 A;  1HSK A;  3S1D A;  1E8G A;  2VFV A;  1DZN A;  2W54 A;  2MBR A;  4UD8 A;  5HMR A;  2R2Z A;  1UXY A;  3PM9 A;  5FXF A;  3HRD C;  1WVE A;  4O95 A;  2AXR A;  3AMZ A;  4JB1 A;  4PVJ A;  2QPM A;  1QLT A;  5G5H B;  1JRP A;  1F0X A;  3AM9 A;  4MLA A;  5AE3 A;  1N63 C;  1W1L A;  2BVG A;  3D2D A;  2Q4W A;  2UUV A;  5AWV A;  4ML8 A;  1N5W C;  1V97 A;  1VDV A;  2W55 A;  5G5G B;  5K8E A;  2QKN A;  3HSU A;  3NVY B;  1W1J A;  1DIQ A;  2WDW A;  2Y08 A;  2Y3S A;  3B9J B;  3TSH A;  1W1Q A;  1DII A;  2VFU A;  3KJM A;  1W1M A;  2W3S A;  1W1O A;  5ADZ A;  3S1F A;  3ETR B;  1VAO A;  2GQT A;  3AN1 A;  4OAL A;  5I1W A;  5AE2 A;  3FW7 A;  4BBY A;  1W1R A;  4BCA A;  3LAE A;  4HG0 A;  3C0P A;  2Y3R A;  1E8F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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