4JB1A

Crystal structure of p. aeruginosa murb in complex with nadp+
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
337
structure length
337
Chain Sequence
LELQEHCSLKPYNTFGIDVRARLLAHARDEADVREALALARERGLPLLVIGGGSNLLLTRDVEALVLRMASQGRRIVSDAADSVLVEAEAGEAWDPFVQWSLERGLAGLENLSLIPGTVGAAPMQNIGAYGVELKDVFDSLTALDRQDGTLREFDRQACRFGYRDSLFKQEPDRWLILRVRLRLTRRERLHLDYGPVRQRLEEEGIASPTARDVSRVICAIRREKLPDPAVLGNAGSFFKNPLVDATQAERLRQAFPDLVGYPQADGRLKLAAGWLIDKGGWKGFRDGPVGVHAQQALVLVNHGGATGAQVRALAERIQEDVRRRFGVELEPEPNLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords UDP-N-acetylenolpyruvoylglucosamine reductase
publication title Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 109
structure length 337
sequence length 337
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2013-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4jb1A01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4jb1A02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 4jb1A03
3FW7A 5FXEA 3SR6B 1W1RA 3FWAA 1DIQA 2BVHA 3TSJA 4UD8A 2E3TA 4ML8A 3S1EA 1N5XA 1QLTA 3S1DA 4DNSA 5G5GB 1E0YA 1N5WC 2GQTA 1FO4A 3S1CA 2YVSA 3W8ZA 5AE3A 3NRZB 3JS8A 4ZOHB 3I99A 1ZXIC 4PVJA 4PWCA 4XLOA 2VFSA 1FFVC 1N62C 2QPMA 4PVHA 3FW9A 1FIQB 4EC3A 2I0KA 4PWBA 3B9JB 3NS1B 3KJMA 1SB3B 1V97A 2AXRA 3S1FA 3TX1A 1RM6B 1N61C 5FXFA 1DZNA 1W1LA 2PLIA 3HRDC 1N60C 2VAOA 2Q4WA 5ADZA 1W1QA 1W1OA 1UXYA 2W3SA 3ETRB 4JAYA 1N63C 4PVEA 2P4PA 5D79A 1ZR6A 2VFUA 4JB1A 1MBTA 4PYTA 3C0PA 5AE1A 1AHVA 2MBRA 3AMZA 4OALA 3DEDA 3LLBA 3NVYB 3D2DA 3W8WA 1E8GA 2VFTA 3BW7A 3DQ0A 5AE2A 4BCAA 3AN1A 3NVVB 1WVEA 3TSHA 5HHZA 2OAIA 1F0XA 1MBBA 5HMRA 1FFUC 1DIIA 3AM9A 2R2ZA 2RK5A 1W1JA 4BC7A 3W8XA 1HSKA 5FXPA 5HQXA 2PLSA 1JRPA 1E8HA 4BC9A 3GSYA 4MLAA 3PM9A 2P13A 1AHZA 2BVGA 2VFVA 2NQWA 3NVWB 2BVFA 2R8DA 1T3QC 3NVZB 1E8FA 2EXRA 5FXDA 1WVFA 1VDVA 3VTEA 4BBYA 2O3GA 3LAEA 2QKNA 2W55A 4HG0A 1WYGA 2W54A 2Q85A 1AHUA 3D2HA 1W1SA 2VFRA 1QLUA 3EUB3 4O95A 1I19A 4PVKA 3D2JA 1VAOA 2W3RA 5G5HB 3FW8A 1W1MA 2P3HA 2GQUA 1JROA 1W1KA 4PZFA
chains in the Genus database with same CATH superfamily
3FW7A 5FXEA 3SR6B 1W1RA 3FWAA 1DIQA 2BVHA 3TSJA 4UD8A 2E3TA 4ML8A 3S1EA 1N5XA 2IPIA 1QLTA 3S1DA 4DNSA 5L6FA 5G5GB 1E0YA 1N5WC 2WDWA 5I1WA 3RJAA 2GQTA 1FO4A 3EJBB 3S1CA 2YVSA 3W8ZA 5AE3A 3NRZB 2UUUA 3JS8A 4ZOHB 3I99A 1ZXIC 4PVJA 4PWCA 4XLOA 2VFSA 1FFVC 1N62C 2QPMA 4PVHA 3FW9A 1FIQB 4EC3A 2I0KA 4PWBA 3B9JB 3NS1B 3KJMA 1SB3B 1V97A 2AXRA 3S1FA 3TX1A 1RM6B 1N61C 5FXFA 1DZNA 1W1LA 2PLIA 3HRDC 1N60C 2VAOA 3HSUA 2Q4WA 5ADZA 1W1QA 1W1OA 1UXYA 2W3SA 3ETRB 4JAYA 1N63C 4PVEA 3PQBA 5AWVA 2P4PA 5D79A 1ZR6A 2VFUA 4JB1A 1MBTA 4PYTA 3EJEB 3C0PA 5AE1A 1AHVA 2MBRA 3AMZA 3EJDB 4OALA 3POPA 3NVYB 3DEDA 3LLBA 3D2DA 2Y3RA 3W8WA 1E8GA 2VFTA 3BW7A 3DQ0A 5AE2A 4BCAA 3AN1A 5K8EA 3NVVB 3RJ8A 1WVEA 3TSHA 5HHZA 2OAIA 1F0XA 1MBBA 5HMRA 1FFUC 1DIIA 3AM9A 2R2ZA 2RK5A 2UUVA 1W1JA 4BC7A 3W8XA 1HSKA 5FXPA 5HQXA 2PLSA 2Y3SA 1JRPA 1E8HA 4BC9A 3GSYA 4MLAA 3PM9A 2P13A 1AHZA 2BVGA 2VFVA 3NVWB 2NQWA 2BVFA 2R8DA 1T3QC 3NVZB 1E8FA 2EXRA 5FXDA 1WVFA 1VDVA 3VTEA 4BBYA 2O3GA 3LAEA 2QKNA 2W55A 4HG0A 1WYGA 2W54A 2Q85A 1AHUA 3D2HA 1W1SA 2Y4GA 2VFRA 1QLUA 3EUB3 4O95A 5L6GA 1I19A 4PVKA 3D2JA 1VAOA 2W3RA 5G5HB 3FW8A 1W1MA 2P3HA 5I1VA 2GQUA 1JROA 1W1KA 4PZFA 2Y08A
chains in the Genus database with same CATH topology
3FW7A 5FXEA 3SR6B 1W1RA 3FWAA 1DIQA 2BVHA 3TSJA 4UD8A 2E3TA 4ML8A 3S1EA 1N5XA 2IPIA 1QLTA 3S1DA 4DNSA 5L6FA 5G5GB 1E0YA 1N5WC 2WDWA 5I1WA 3RJAA 2GQTA 1FO4A 3S1CA 2YVSA 3W8ZA 5AE3A 3NRZB 2UUUA 3JS8A 4ZOHB 3I99A 1ZXIC 4PVJA 4PWCA 4XLOA 2VFSA 1FFVC 1N62C 2QPMA 4PVHA 3FW9A 1FIQB 4EC3A 2I0KA 4PWBA 3B9JB 3NS1B 3KJMA 1SB3B 1V97A 2AXRA 3S1FA 3TX1A 1RM6B 1N61C 5FXFA 1DZNA 1W1LA 2PLIA 3HRDC 1N60C 2VAOA 3HSUA 2Q4WA 5ADZA 1W1QA 1W1OA 1UXYA 2W3SA 3ETRB 4JAYA 1N63C 4PVEA 3PQBA 5AWVA 2P4PA 5D79A 1ZR6A 2VFUA 4JB1A 1MBTA 4PYTA 3C0PA 5AE1A 1AHVA 2MBRA 3AMZA 4OALA 3POPA 3DEDA 3LLBA 3NVYB 3D2DA 2Y3RA 3W8WA 1E8GA 2VFTA 3BW7A 3DQ0A 5AE2A 4BCAA 3AN1A 5K8EA 3NVVB 3RJ8A 1WVEA 3TSHA 5HHZA 2OAIA 1F0XA 1MBBA 5HMRA 1FFUC 1DIIA 3AM9A 2R2ZA 2RK5A 2UUVA 1W1JA 4BC7A 3W8XA 1HSKA 5FXPA 5HQXA 2PLSA 2Y3SA 1JRPA 1E8HA 4BC9A 3GSYA 4MLAA 3PM9A 2P13A 1AHZA 2BVGA 2VFVA 2NQWA 3NVWB 2BVFA 2R8DA 1T3QC 3NVZB 1E8FA 2EXRA 5FXDA 1WVFA 1VDVA 3VTEA 4BBYA 2O3GA 3LAEA 2QKNA 2W55A 4HG0A 1WYGA 2W54A 2Q85A 1AHUA 3D2HA 1W1SA 2Y4GA 2VFRA 1QLUA 3EUB3 4O95A 5L6GA 1I19A 4PVKA 3D2JA 1VAOA 2W3RA 5G5HB 3FW8A 1W1MA 2P3HA 5I1VA 2GQUA 1JROA 1W1KA 4PZFA 2Y08A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FW7 A;  5FXE A;  3SR6 B;  1W1R A;  3FWA A;  1DIQ A;  2BVH A;  3TSJ A;  4UD8 A;  2E3T A;  4ML8 A;  3S1E A;  1N5X A;  1QLT A;  3S1D A;  4DNS A;  5G5G B;  1E0Y A;  1N5W C;  2GQT A;  1FO4 A;  3S1C A;  2YVS A;  3W8Z A;  5AE3 A;  3NRZ B;  3JS8 A;  4ZOH B;  3I99 A;  1ZXI C;  4PVJ A;  4PWC A;  4XLO A;  2VFS A;  1FFV C;  1N62 C;  2QPM A;  4PVH A;  3FW9 A;  1FIQ B;  4EC3 A;  2I0K A;  4PWB A;  3B9J B;  3NS1 B;  3KJM A;  1SB3 B;  1V97 A;  2AXR A;  3S1F A;  3TX1 A;  1RM6 B;  1N61 C;  5FXF A;  1DZN A;  1W1L A;  2PLI A;  3HRD C;  1N60 C;  2VAO A;  2Q4W A;  5ADZ A;  1W1Q A;  1W1O A;  1UXY A;  2W3S A;  3ETR B;  4JAY A;  1N63 C;  4PVE A;  2P4P A;  5D79 A;  1ZR6 A;  2VFU A;  4JB1 A;  1MBT A;  4PYT A;  3C0P A;  5AE1 A;  1AHV A;  2MBR A;  3AMZ A;  4OAL A;  3DED A;  3LLB A;  3NVY B;  3D2D A;  3W8W A;  1E8G A;  2VFT A;  3BW7 A;  3DQ0 A;  5AE2 A;  4BCA A;  3AN1 A;  3NVV B;  1WVE A;  3TSH A;  5HHZ A;  2OAI A;  1F0X A;  1MBB A;  5HMR A;  1FFU C;  1DII A;  3AM9 A;  2R2Z A;  2RK5 A;  1W1J A;  4BC7 A;  3W8X A;  1HSK A;  5FXP A;  5HQX A;  2PLS A;  1JRP A;  1E8H A;  4BC9 A;  3GSY A;  4MLA A;  3PM9 A;  2P13 A;  1AHZ A;  2BVG A;  2VFV A;  2NQW A;  3NVW B;  2BVF A;  2R8D A;  1T3Q C;  3NVZ B;  1E8F A;  2EXR A;  5FXD A;  1WVF A;  1VDV A;  3VTE A;  4BBY A;  2O3G A;  3LAE A;  2QKN A;  2W55 A;  4HG0 A;  1WYG A;  2W54 A;  2Q85 A;  1AHU A;  3D2H A;  1W1S A;  2VFR A;  1QLU A;  3EUB 3;  4O95 A;  1I19 A;  4PVK A;  3D2J A;  1VAO A;  2W3R A;  5G5H B;  3FW8 A;  1W1M A;  2P3H A;  2GQU A;  1JRO A;  1W1K A;  4PZF A; 
#chains in the Genus database with same CATH topology
 3FW7 A;  5FXE A;  3SR6 B;  1W1R A;  3FWA A;  1DIQ A;  2BVH A;  3TSJ A;  4UD8 A;  2E3T A;  4ML8 A;  3S1E A;  1N5X A;  2IPI A;  1QLT A;  3S1D A;  4DNS A;  5L6F A;  5G5G B;  1E0Y A;  1N5W C;  2WDW A;  5I1W A;  3RJA A;  2GQT A;  1FO4 A;  3EJB B;  3S1C A;  2YVS A;  3W8Z A;  5AE3 A;  3NRZ B;  2UUU A;  3JS8 A;  4ZOH B;  3I99 A;  1ZXI C;  4PVJ A;  4PWC A;  4XLO A;  2VFS A;  1FFV C;  1N62 C;  2QPM A;  4PVH A;  3FW9 A;  1FIQ B;  4EC3 A;  2I0K A;  4PWB A;  3B9J B;  3NS1 B;  3KJM A;  1SB3 B;  1V97 A;  2AXR A;  3S1F A;  3TX1 A;  1RM6 B;  1N61 C;  5FXF A;  1DZN A;  1W1L A;  2PLI A;  3HRD C;  1N60 C;  2VAO A;  3HSU A;  2Q4W A;  5ADZ A;  1W1Q A;  1W1O A;  1UXY A;  2W3S A;  3ETR B;  4JAY A;  1N63 C;  4PVE A;  3PQB A;  5AWV A;  2P4P A;  5D79 A;  1ZR6 A;  2VFU A;  4JB1 A;  1MBT A;  4PYT A;  3EJE B;  3C0P A;  5AE1 A;  1AHV A;  2MBR A;  3AMZ A;  3EJD B;  4OAL A;  3POP A;  3NVY B;  3DED A;  3LLB A;  3D2D A;  2Y3R A;  3W8W A;  1E8G A;  2VFT A;  3BW7 A;  3DQ0 A;  5AE2 A;  4BCA A;  3AN1 A;  5K8E A;  3NVV B;  3RJ8 A;  1WVE A;  3TSH A;  5HHZ A;  2OAI A;  1F0X A;  1MBB A;  5HMR A;  1FFU C;  1DII A;  3AM9 A;  2R2Z A;  2RK5 A;  2UUV A;  1W1J A;  4BC7 A;  3W8X A;  1HSK A;  5FXP A;  5HQX A;  2PLS A;  2Y3S A;  1JRP A;  1E8H A;  4BC9 A;  3GSY A;  4MLA A;  3PM9 A;  2P13 A;  1AHZ A;  2BVG A;  2VFV A;  3NVW B;  2NQW A;  2BVF A;  2R8D A;  1T3Q C;  3NVZ B;  1E8F A;  2EXR A;  5FXD A;  1WVF A;  1VDV A;  3VTE A;  4BBY A;  2O3G A;  3LAE A;  2QKN A;  2W55 A;  4HG0 A;  1WYG A;  2W54 A;  2Q85 A;  1AHU A;  3D2H A;  1W1S A;  2Y4G A;  2VFR A;  1QLU A;  3EUB 3;  4O95 A;  5L6G A;  1I19 A;  4PVK A;  3D2J A;  1VAO A;  2W3R A;  5G5H B;  3FW8 A;  1W1M A;  2P3H A;  5I1V A;  2GQU A;  1JRO A;  1W1K A;  4PZF A;  2Y08 A; 
#chains in the Genus database with same CATH homology
 3FW7 A;  5FXE A;  3SR6 B;  1W1R A;  3FWA A;  1DIQ A;  2BVH A;  3TSJ A;  4UD8 A;  2E3T A;  4ML8 A;  3S1E A;  1N5X A;  2IPI A;  1QLT A;  3S1D A;  4DNS A;  5L6F A;  5G5G B;  1E0Y A;  1N5W C;  2WDW A;  5I1W A;  3RJA A;  2GQT A;  1FO4 A;  3S1C A;  2YVS A;  3W8Z A;  5AE3 A;  3NRZ B;  2UUU A;  3JS8 A;  4ZOH B;  3I99 A;  1ZXI C;  4PVJ A;  4PWC A;  4XLO A;  2VFS A;  1FFV C;  1N62 C;  2QPM A;  4PVH A;  3FW9 A;  1FIQ B;  4EC3 A;  2I0K A;  4PWB A;  3B9J B;  3NS1 B;  3KJM A;  1SB3 B;  1V97 A;  2AXR A;  3S1F A;  3TX1 A;  1RM6 B;  1N61 C;  5FXF A;  1DZN A;  1W1L A;  2PLI A;  3HRD C;  1N60 C;  2VAO A;  3HSU A;  2Q4W A;  5ADZ A;  1W1Q A;  1W1O A;  1UXY A;  2W3S A;  3ETR B;  4JAY A;  1N63 C;  4PVE A;  3PQB A;  5AWV A;  2P4P A;  5D79 A;  1ZR6 A;  2VFU A;  4JB1 A;  1MBT A;  4PYT A;  3C0P A;  5AE1 A;  1AHV A;  2MBR A;  3AMZ A;  4OAL A;  3POP A;  3DED A;  3LLB A;  3NVY B;  3D2D A;  2Y3R A;  3W8W A;  1E8G A;  2VFT A;  3BW7 A;  3DQ0 A;  5AE2 A;  4BCA A;  3AN1 A;  5K8E A;  3NVV B;  3RJ8 A;  1WVE A;  3TSH A;  5HHZ A;  2OAI A;  1F0X A;  1MBB A;  5HMR A;  1FFU C;  1DII A;  3AM9 A;  2R2Z A;  2RK5 A;  2UUV A;  1W1J A;  4BC7 A;  3W8X A;  1HSK A;  5FXP A;  5HQX A;  2PLS A;  2Y3S A;  1JRP A;  1E8H A;  4BC9 A;  3GSY A;  4MLA A;  3PM9 A;  2P13 A;  1AHZ A;  2BVG A;  2VFV A;  2NQW A;  3NVW B;  2BVF A;  2R8D A;  1T3Q C;  3NVZ B;  1E8F A;  2EXR A;  5FXD A;  1WVF A;  1VDV A;  3VTE A;  4BBY A;  2O3G A;  3LAE A;  2QKN A;  2W55 A;  4HG0 A;  1WYG A;  2W54 A;  2Q85 A;  1AHU A;  3D2H A;  1W1S A;  2Y4G A;  2VFR A;  1QLU A;  3EUB 3;  4O95 A;  5L6G A;  1I19 A;  4PVK A;  3D2J A;  1VAO A;  2W3R A;  5G5H B;  3FW8 A;  1W1M A;  2P3H A;  5I1V A;  2GQU A;  1JRO A;  1W1K A;  4PZF A;  2Y08 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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