2VAOA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase in complex with isoeugenol
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
555
structure length
555
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISSKDQIVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Flavoenzyme
molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
pubmed doi rcsb
total genus 161
structure length 555
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 1997-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 2vaoA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2vaoA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2vaoA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 2vaoA03
1MBTA 4ZOHB 2VFUA 3S1CA 1W1MA 2VFTA 1F0XA 2BVGA 3NVYB 1I19A 1V97A 1DIIA 5HHZA 4BBYA 4PVJA 1T3QC 3FWAA 1ZR6A 1N5XA 4PVHA 3NVWB 3B9JB 3GSYA 1N63C 4PZFA 2P4PA 5AE1A 1RM6B 1FFUC 3ETRB 5HMRA 2NQWA 3AM9A 4ML8A 4JB1A 2GQUA 2PLSA 1SB3B 3TSJA 3S1EA 2R8DA 3LLBA 2VFRA 2W3RA 5D79A 2PLIA 2EXRA 3LAEA 4OALA 2VFSA 5FXDA 2BVHA 5AE2A 5ADZA 3NVVB 2BVFA 4BCAA 4PVEA 3DEDA 1W1LA 5G5GB 2W55A 2R2ZA 1HSKA 1JROA 1W1QA 1ZXIC 1WVFA 1QLTA 3NS1B 3S1FA 1N60C 1W1SA 2YVSA 3S1DA 1DZNA 4PWCA 2AXRA 1E8HA 1W1KA 3W8WA 4MLAA 3PM9A 5FXPA 2Q85A 2Q4WA 5FXEA 1N62C 3JS8A 1VAOA 3D2HA 2OAIA 2W54A 4PWBA 1N61C 1FFVC 1N5WC 2QPMA 3AN1A 2MBRA 3FW9A 1MBBA 4UD8A 4HG0A 5AE3A 2GQTA 3TX1A 3HRDC 2I0KA 2RK5A 1QLUA 4JAYA 5G5HB 1WVEA 1E8GA 3BW7A 3D2JA 4BC7A 4DNSA 1UXYA 1WYGA 3FW7A 2VAOA 4EC3A 2VFVA 3AMZA 3NVZB 2P3HA 3I99A 3TSHA 3DQ0A 1E8FA 1AHVA 5HQXA 1FIQB 3FW8A 4BC9A 2E3TA 3EUB3 1AHZA 1AHUA 3NRZB 1DIQA 2W3SA 3SR6B 3D2DA 1JRPA 3KJMA 1FO4A 1VDVA 3VTEA 4O95A 3W8XA 2P13A 5FXFA 1W1OA 1W1JA 4XLOA 3W8ZA 2QKNA 3C0PA 2O3GA 4PYTA 1E0YA 4PVKA 1W1RA
chains in the Genus database with same CATH superfamily
1MBTA 4ZOHB 2VFUA 3S1CA 1W1MA 2VFTA 5I1WA 1F0XA 2BVGA 3NVYB 1I19A 1V97A 1DIIA 3POPA 5HHZA 5K8EA 4BBYA 3EJEB 4PVJA 1T3QC 3FWAA 1ZR6A 2IPIA 2UUVA 1N5XA 4PVHA 2WDWA 3NVWB 3B9JB 3GSYA 1N63C 4PZFA 2P4PA 5AE1A 1RM6B 1FFUC 2Y3SA 3ETRB 5HMRA 2NQWA 3AM9A 2Y3RA 4ML8A 4JB1A 2GQUA 2PLSA 1SB3B 3TSJA 3S1EA 2R8DA 3LLBA 2VFRA 2W3RA 5D79A 2PLIA 2EXRA 3LAEA 4OALA 2VFSA 5FXDA 2BVHA 5AE2A 5ADZA 3NVVB 2BVFA 2Y08A 4BCAA 4PVEA 3DEDA 1W1LA 5G5GB 3EJDB 2W55A 2R2ZA 1HSKA 1JROA 1W1QA 1ZXIC 1WVFA 1QLTA 3NS1B 3S1FA 5L6FA 1N60C 1W1SA 2YVSA 3S1DA 1DZNA 5L6GA 4PWCA 2AXRA 1E8HA 1W1KA 3PQBA 3W8WA 4MLAA 3EJBB 3PM9A 5FXPA 2Q85A 2Q4WA 2UUUA 5FXEA 1N62C 3JS8A 2Y4GA 1VAOA 3D2HA 2OAIA 2W54A 4PWBA 1N61C 3RJAA 5I1VA 1FFVC 1N5WC 2QPMA 3AN1A 2MBRA 3FW9A 1MBBA 4UD8A 4HG0A 5AE3A 2GQTA 3TX1A 3HRDC 2I0KA 2RK5A 1QLUA 4JAYA 5G5HB 1WVEA 1E8GA 3BW7A 3D2JA 4BC7A 4DNSA 1UXYA 1WYGA 3FW7A 2VAOA 4EC3A 2VFVA 3AMZA 3NVZB 2P3HA 3I99A 3TSHA 3DQ0A 1E8FA 1AHVA 5HQXA 1FIQB 3FW8A 4BC9A 2E3TA 3EUB3 1AHZA 1AHUA 3NRZB 1DIQA 3HSUA 2W3SA 3SR6B 3D2DA 1JRPA 3KJMA 1FO4A 5AWVA 1VDVA 3VTEA 4O95A 3W8XA 2P13A 5FXFA 3RJ8A 1W1OA 1W1JA 4XLOA 3W8ZA 2QKNA 3C0PA 2O3GA 4PYTA 1E0YA 4PVKA 1W1RA
chains in the Genus database with same CATH topology
1MBTA 4ZOHB 2VFUA 3S1CA 1W1MA 2VFTA 5I1WA 1F0XA 2BVGA 3NVYB 1I19A 1V97A 1DIIA 3POPA 5HHZA 5K8EA 4BBYA 4PVJA 1T3QC 3FWAA 1ZR6A 2IPIA 2UUVA 1N5XA 4PVHA 2WDWA 3NVWB 3B9JB 3GSYA 1N63C 4PZFA 2P4PA 5AE1A 1RM6B 1FFUC 2Y3SA 3ETRB 5HMRA 2NQWA 3AM9A 2Y3RA 4ML8A 4JB1A 2GQUA 2PLSA 1SB3B 3TSJA 3S1EA 2R8DA 3LLBA 2VFRA 2W3RA 5D79A 2PLIA 2EXRA 3LAEA 4OALA 2VFSA 5FXDA 2BVHA 5AE2A 5ADZA 2Y08A 2BVFA 3NVVB 4BCAA 4PVEA 3DEDA 1W1LA 5G5GB 2W55A 2R2ZA 1HSKA 1JROA 1W1QA 1ZXIC 1WVFA 1QLTA 3NS1B 3S1FA 5L6FA 1N60C 1W1SA 2YVSA 3S1DA 1DZNA 5L6GA 4PWCA 2AXRA 1E8HA 1W1KA 3PQBA 3W8WA 4MLAA 3PM9A 5FXPA 2Q85A 2Q4WA 2UUUA 5FXEA 1N62C 3JS8A 2Y4GA 1VAOA 3D2HA 2OAIA 2W54A 4PWBA 1N61C 3RJAA 5I1VA 1FFVC 1N5WC 2QPMA 3AN1A 2MBRA 3FW9A 1MBBA 4UD8A 4HG0A 5AE3A 2GQTA 3TX1A 3HRDC 2I0KA 2RK5A 1QLUA 4JAYA 5G5HB 1WVEA 1E8GA 3BW7A 3D2JA 4BC7A 4DNSA 1UXYA 1WYGA 3FW7A 2VAOA 4EC3A 2VFVA 3AMZA 3NVZB 2P3HA 3I99A 3TSHA 3DQ0A 1E8FA 1AHVA 5HQXA 1FIQB 3FW8A 4BC9A 2E3TA 3EUB3 1AHZA 1AHUA 3NRZB 1DIQA 3HSUA 2W3SA 3SR6B 3D2DA 1JRPA 3KJMA 1FO4A 5AWVA 1VDVA 3VTEA 4O95A 3W8XA 2P13A 5FXFA 3RJ8A 1W1OA 1W1JA 4XLOA 3W8ZA 2QKNA 3C0PA 2O3GA 4PYTA 1E0YA 4PVKA 1W1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MBT A;  4ZOH B;  2VFU A;  3S1C A;  1W1M A;  2VFT A;  1F0X A;  2BVG A;  3NVY B;  1I19 A;  1V97 A;  1DII A;  5HHZ A;  4BBY A;  4PVJ A;  1T3Q C;  3FWA A;  1ZR6 A;  1N5X A;  4PVH A;  3NVW B;  3B9J B;  3GSY A;  1N63 C;  4PZF A;  2P4P A;  5AE1 A;  1RM6 B;  1FFU C;  3ETR B;  5HMR A;  2NQW A;  3AM9 A;  4ML8 A;  4JB1 A;  2GQU A;  2PLS A;  1SB3 B;  3TSJ A;  3S1E A;  2R8D A;  3LLB A;  2VFR A;  2W3R A;  5D79 A;  2PLI A;  2EXR A;  3LAE A;  4OAL A;  2VFS A;  5FXD A;  2BVH A;  5AE2 A;  5ADZ A;  3NVV B;  2BVF A;  4BCA A;  4PVE A;  3DED A;  1W1L A;  5G5G B;  2W55 A;  2R2Z A;  1HSK A;  1JRO A;  1W1Q A;  1ZXI C;  1WVF A;  1QLT A;  3NS1 B;  3S1F A;  1N60 C;  1W1S A;  2YVS A;  3S1D A;  1DZN A;  4PWC A;  2AXR A;  1E8H A;  1W1K A;  3W8W A;  4MLA A;  3PM9 A;  5FXP A;  2Q85 A;  2Q4W A;  5FXE A;  1N62 C;  3JS8 A;  1VAO A;  3D2H A;  2OAI A;  2W54 A;  4PWB A;  1N61 C;  1FFV C;  1N5W C;  2QPM A;  3AN1 A;  2MBR A;  3FW9 A;  1MBB A;  4UD8 A;  4HG0 A;  5AE3 A;  2GQT A;  3TX1 A;  3HRD C;  2I0K A;  2RK5 A;  1QLU A;  4JAY A;  5G5H B;  1WVE A;  1E8G A;  3BW7 A;  3D2J A;  4BC7 A;  4DNS A;  1UXY A;  1WYG A;  3FW7 A;  2VAO A;  4EC3 A;  2VFV A;  3AMZ A;  3NVZ B;  2P3H A;  3I99 A;  3TSH A;  3DQ0 A;  1E8F A;  1AHV A;  5HQX A;  1FIQ B;  3FW8 A;  4BC9 A;  2E3T A;  3EUB 3;  1AHZ A;  1AHU A;  3NRZ B;  1DIQ A;  2W3S A;  3SR6 B;  3D2D A;  1JRP A;  3KJM A;  1FO4 A;  1VDV A;  3VTE A;  4O95 A;  3W8X A;  2P13 A;  5FXF A;  1W1O A;  1W1J A;  4XLO A;  3W8Z A;  2QKN A;  3C0P A;  2O3G A;  4PYT A;  1E0Y A;  4PVK A;  1W1R A; 
#chains in the Genus database with same CATH topology
 1MBT A;  4ZOH B;  2VFU A;  3S1C A;  1W1M A;  2VFT A;  5I1W A;  1F0X A;  2BVG A;  3NVY B;  1I19 A;  1V97 A;  1DII A;  3POP A;  5HHZ A;  5K8E A;  4BBY A;  3EJE B;  4PVJ A;  1T3Q C;  3FWA A;  1ZR6 A;  2IPI A;  2UUV A;  1N5X A;  4PVH A;  2WDW A;  3NVW B;  3B9J B;  3GSY A;  1N63 C;  4PZF A;  2P4P A;  5AE1 A;  1RM6 B;  1FFU C;  2Y3S A;  3ETR B;  5HMR A;  2NQW A;  3AM9 A;  2Y3R A;  4ML8 A;  4JB1 A;  2GQU A;  2PLS A;  1SB3 B;  3TSJ A;  3S1E A;  2R8D A;  3LLB A;  2VFR A;  2W3R A;  5D79 A;  2PLI A;  2EXR A;  3LAE A;  4OAL A;  2VFS A;  5FXD A;  2BVH A;  5AE2 A;  5ADZ A;  3NVV B;  2BVF A;  2Y08 A;  4BCA A;  4PVE A;  3DED A;  1W1L A;  5G5G B;  3EJD B;  2W55 A;  2R2Z A;  1HSK A;  1JRO A;  1W1Q A;  1ZXI C;  1WVF A;  1QLT A;  3NS1 B;  3S1F A;  5L6F A;  1N60 C;  1W1S A;  2YVS A;  3S1D A;  1DZN A;  5L6G A;  4PWC A;  2AXR A;  1E8H A;  1W1K A;  3PQB A;  3W8W A;  4MLA A;  3EJB B;  3PM9 A;  5FXP A;  2Q85 A;  2Q4W A;  2UUU A;  5FXE A;  1N62 C;  3JS8 A;  2Y4G A;  1VAO A;  3D2H A;  2OAI A;  2W54 A;  4PWB A;  1N61 C;  3RJA A;  5I1V A;  1FFV C;  1N5W C;  2QPM A;  3AN1 A;  2MBR A;  3FW9 A;  1MBB A;  4UD8 A;  4HG0 A;  5AE3 A;  2GQT A;  3TX1 A;  3HRD C;  2I0K A;  2RK5 A;  1QLU A;  4JAY A;  5G5H B;  1WVE A;  1E8G A;  3BW7 A;  3D2J A;  4BC7 A;  4DNS A;  1UXY A;  1WYG A;  3FW7 A;  2VAO A;  4EC3 A;  2VFV A;  3AMZ A;  3NVZ B;  2P3H A;  3I99 A;  3TSH A;  3DQ0 A;  1E8F A;  1AHV A;  5HQX A;  1FIQ B;  3FW8 A;  4BC9 A;  2E3T A;  3EUB 3;  1AHZ A;  1AHU A;  3NRZ B;  1DIQ A;  3HSU A;  2W3S A;  3SR6 B;  3D2D A;  1JRP A;  3KJM A;  1FO4 A;  5AWV A;  1VDV A;  3VTE A;  4O95 A;  3W8X A;  2P13 A;  5FXF A;  3RJ8 A;  1W1O A;  1W1J A;  4XLO A;  3W8Z A;  2QKN A;  3C0P A;  2O3G A;  4PYT A;  1E0Y A;  4PVK A;  1W1R A; 
#chains in the Genus database with same CATH homology
 1MBT A;  4ZOH B;  2VFU A;  3S1C A;  1W1M A;  2VFT A;  5I1W A;  1F0X A;  2BVG A;  3NVY B;  1I19 A;  1V97 A;  1DII A;  3POP A;  5HHZ A;  5K8E A;  4BBY A;  4PVJ A;  1T3Q C;  3FWA A;  1ZR6 A;  2IPI A;  2UUV A;  1N5X A;  4PVH A;  2WDW A;  3NVW B;  3B9J B;  3GSY A;  1N63 C;  4PZF A;  2P4P A;  5AE1 A;  1RM6 B;  1FFU C;  2Y3S A;  3ETR B;  5HMR A;  2NQW A;  3AM9 A;  2Y3R A;  4ML8 A;  4JB1 A;  2GQU A;  2PLS A;  1SB3 B;  3TSJ A;  3S1E A;  2R8D A;  3LLB A;  2VFR A;  2W3R A;  5D79 A;  2PLI A;  2EXR A;  3LAE A;  4OAL A;  2VFS A;  5FXD A;  2BVH A;  5AE2 A;  5ADZ A;  2Y08 A;  2BVF A;  3NVV B;  4BCA A;  4PVE A;  3DED A;  1W1L A;  5G5G B;  2W55 A;  2R2Z A;  1HSK A;  1JRO A;  1W1Q A;  1ZXI C;  1WVF A;  1QLT A;  3NS1 B;  3S1F A;  5L6F A;  1N60 C;  1W1S A;  2YVS A;  3S1D A;  1DZN A;  5L6G A;  4PWC A;  2AXR A;  1E8H A;  1W1K A;  3PQB A;  3W8W A;  4MLA A;  3PM9 A;  5FXP A;  2Q85 A;  2Q4W A;  2UUU A;  5FXE A;  1N62 C;  3JS8 A;  2Y4G A;  1VAO A;  3D2H A;  2OAI A;  2W54 A;  4PWB A;  1N61 C;  3RJA A;  5I1V A;  1FFV C;  1N5W C;  2QPM A;  3AN1 A;  2MBR A;  3FW9 A;  1MBB A;  4UD8 A;  4HG0 A;  5AE3 A;  2GQT A;  3TX1 A;  3HRD C;  2I0K A;  2RK5 A;  1QLU A;  4JAY A;  5G5H B;  1WVE A;  1E8G A;  3BW7 A;  3D2J A;  4BC7 A;  4DNS A;  1UXY A;  1WYG A;  3FW7 A;  2VAO A;  4EC3 A;  2VFV A;  3AMZ A;  3NVZ B;  2P3H A;  3I99 A;  3TSH A;  3DQ0 A;  1E8F A;  1AHV A;  5HQX A;  1FIQ B;  3FW8 A;  4BC9 A;  2E3T A;  3EUB 3;  1AHZ A;  1AHU A;  3NRZ B;  1DIQ A;  3HSU A;  2W3S A;  3SR6 B;  3D2D A;  1JRP A;  3KJM A;  1FO4 A;  5AWV A;  1VDV A;  3VTE A;  4O95 A;  3W8X A;  2P13 A;  5FXF A;  3RJ8 A;  1W1O A;  1W1J A;  4XLO A;  3W8Z A;  2QKN A;  3C0P A;  2O3G A;  4PYT A;  1E0Y A;  4PVK A;  1W1R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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