2VAOA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase in complex with isoeugenol
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
555
structure length
555
Chain Sequence
b'EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISSKDQIVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
publication title Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
pubmed doi rcsb
molecule tags Flavoenzyme
total genus 161
structure length 555
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 1997-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 2vaoA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2vaoA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2vaoA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 2vaoA03
2PLSA 2GQUA 4PYTA 1JRPA 1QLUA 1DIIA 1N5WC 2P13A 3HRDC 3W8ZA 4ZOHB 3FW9A 1SB3B 2QKNA 4PZFA 1MBBA 3D2DA 3NVWB 5G5GB 2Q85A 3S1EA 4BC7A 3FW8A 1E8HA 1W1MA 1AHUA 1ZXIC 4BBYA 1V97A 3D2JA 5HQXA 2YVSA 3TSJA 2EXRA 3DEDA 2VFTA 2AXRA 5FXDA 2W55A 4PWCA 1AHVA 2QPMA 3SR6B 2RK5A 2VFUA 2PLIA 2P4PA 1QLTA 3DQ0A 3GSYA 3W8WA 1N5XA 2BVGA 3LAEA 3NRZB 3TSHA 3FWAA 3W8XA 2OAIA 2W3SA 1WVEA 2R2ZA 2O3GA 1W1JA 2VFSA 4PVHA 4UD8A 1UXYA 1FO4A 3NVVB 2E3TA 1W1LA 2NQWA 2GQTA 1T3QC 2VFRA 3PM9A 1F0XA 4EC3A 3NS1B 4OALA 2BVFA 1VAOA 4JAYA 3C0PA 1N60C 1W1RA 4PVEA 2W54A 3D2HA 1FFVC 3AM9A 4DNSA 1HSKA 1N63C 3AMZA 3EUB3 1N62C 4HG0A 1W1SA 3TX1A 3AN1A 3NVYB 2R8DA 5AE3A 4PVJA 1RM6B 2MBRA 1N61C 5HHZA 1FIQB 3NVZB 2VAOA 5FXEA 2VFVA 2BVHA 4PWBA 3VTEA 4JB1A 4BCAA 5AE2A 1WYGA 4MLAA 1W1OA 5ADZA 2W3RA 5HMRA 5FXPA 5G5HB 3JS8A 1WVFA 1W1KA 3ETRB 1E8GA 1E0YA 1VDVA 1FFUC 3B9JB 4ML8A 4XLOA 2P3HA 5D79A 1ZR6A 1DZNA 3BW7A 1E8FA 4BC9A 5FXFA 4O95A 1JROA 1DIQA 3S1CA 1I19A 2I0KA 3S1FA 3I99A 3LLBA 3FW7A 1MBTA 3S1DA 5AE1A 1W1QA 4PVKA 2Q4WA 3KJMA 1AHZA
chains in the Genus database with same CATH superfamily
2PLSA 2GQUA 4PYTA 5I1VA 1JRPA 1QLUA 1DIIA 1N5WC 2P13A 3HRDC 3W8ZA 4ZOHB 3FW9A 1SB3B 2QKNA 4PZFA 1MBBA 3D2DA 3NVWB 5G5GB 2UUUA 3EJEB 2Q85A 3S1EA 4BC7A 3FW8A 1E8HA 1W1MA 1AHUA 1ZXIC 4BBYA 1V97A 3D2JA 5HQXA 5L6FA 2YVSA 3TSJA 2EXRA 3DEDA 2VFTA 2AXRA 5FXDA 2W55A 4PWCA 1AHVA 2QPMA 3SR6B 2RK5A 2VFUA 2PLIA 2P4PA 1QLTA 3DQ0A 3GSYA 3W8WA 1N5XA 2BVGA 3LAEA 2WDWA 3NRZB 3TSHA 3FWAA 3W8XA 2OAIA 2W3SA 1WVEA 2R2ZA 2O3GA 1W1JA 5I1WA 2VFSA 4PVHA 4UD8A 1UXYA 1FO4A 3NVVB 2E3TA 1W1LA 2NQWA 2GQTA 1T3QC 2VFRA 3PM9A 1F0XA 4EC3A 3NS1B 4OALA 2BVFA 1VAOA 4JAYA 3C0PA 3HSUA 1N60C 1W1RA 4PVEA 2W54A 3D2HA 1FFVC 3AM9A 4DNSA 3RJ8A 1HSKA 1N63C 3AMZA 3EUB3 1N62C 4HG0A 1W1SA 3NVYB 3AN1A 3TX1A 2R8DA 5AE3A 4PVJA 1RM6B 2MBRA 1N61C 5HHZA 1FIQB 3POPA 2Y4GA 3NVZB 2VAOA 5FXEA 3EJDB 2VFVA 2BVHA 4PWBA 2UUVA 3VTEA 2Y3SA 4JB1A 4BCAA 5AE2A 1WYGA 4MLAA 5AWVA 1W1OA 5ADZA 2W3RA 3EJBB 5FXPA 5HMRA 2IPIA 5G5HB 3JS8A 1WVFA 1W1KA 3ETRB 2Y08A 1E8GA 1E0YA 1VDVA 1FFUC 5L6GA 5K8EA 3B9JB 4ML8A 4XLOA 2P3HA 2Y3RA 5D79A 1ZR6A 3RJAA 1DZNA 3PQBA 3BW7A 1E8FA 4BC9A 5FXFA 4O95A 1JROA 1DIQA 3S1CA 1I19A 2I0KA 3S1FA 3I99A 3LLBA 3FW7A 1MBTA 3S1DA 5AE1A 1W1QA 4PVKA 2Q4WA 3KJMA 1AHZA
chains in the Genus database with same CATH topology
2PLSA 2GQUA 4PYTA 5I1VA 1JRPA 1QLUA 1DIIA 1N5WC 2P13A 3HRDC 3W8ZA 4ZOHB 3FW9A 1SB3B 2QKNA 4PZFA 1MBBA 3D2DA 3NVWB 5G5GB 2UUUA 2Q85A 3S1EA 4BC7A 3FW8A 1E8HA 1W1MA 1AHUA 1ZXIC 4BBYA 1V97A 3D2JA 5HQXA 5L6FA 2YVSA 3TSJA 2EXRA 3DEDA 2VFTA 2AXRA 5FXDA 2W55A 4PWCA 1AHVA 2QPMA 3SR6B 2RK5A 2VFUA 2PLIA 2P4PA 1QLTA 3DQ0A 3GSYA 3W8WA 1N5XA 2BVGA 3LAEA 2WDWA 3NRZB 3TSHA 3FWAA 3W8XA 2OAIA 2W3SA 1WVEA 2R2ZA 2O3GA 1W1JA 5I1WA 2VFSA 4PVHA 4UD8A 1UXYA 1FO4A 3NVVB 2E3TA 1W1LA 2NQWA 2GQTA 1T3QC 2VFRA 3PM9A 1F0XA 4EC3A 3NS1B 4OALA 2BVFA 1VAOA 4JAYA 3C0PA 3HSUA 1N60C 1W1RA 4PVEA 2W54A 3D2HA 1FFVC 3AM9A 4DNSA 3RJ8A 1HSKA 1N63C 3AMZA 3EUB3 1N62C 4HG0A 1W1SA 3TX1A 3AN1A 3NVYB 2R8DA 5AE3A 4PVJA 1RM6B 2MBRA 1N61C 5HHZA 1FIQB 3POPA 2Y4GA 3NVZB 2VAOA 5FXEA 2VFVA 2BVHA 4PWBA 2UUVA 3VTEA 2Y3SA 4JB1A 4BCAA 5AE2A 1WYGA 4MLAA 5AWVA 1W1OA 5ADZA 2W3RA 5HMRA 5FXPA 2IPIA 5G5HB 3JS8A 1WVFA 1W1KA 3ETRB 2Y08A 1E8GA 1E0YA 1VDVA 1FFUC 5L6GA 5K8EA 3B9JB 4ML8A 4XLOA 2P3HA 2Y3RA 5D79A 1ZR6A 3RJAA 1DZNA 3PQBA 3BW7A 1E8FA 4BC9A 5FXFA 4O95A 1JROA 1DIQA 3S1CA 1I19A 2I0KA 3S1FA 3I99A 3LLBA 3FW7A 1MBTA 3S1DA 5AE1A 1W1QA 4PVKA 2Q4WA 3KJMA 1AHZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PLS A;  2GQU A;  4PYT A;  1JRP A;  1QLU A;  1DII A;  1N5W C;  2P13 A;  3HRD C;  3W8Z A;  4ZOH B;  3FW9 A;  1SB3 B;  2QKN A;  4PZF A;  1MBB A;  3D2D A;  3NVW B;  5G5G B;  2Q85 A;  3S1E A;  4BC7 A;  3FW8 A;  1E8H A;  1W1M A;  1AHU A;  1ZXI C;  4BBY A;  1V97 A;  3D2J A;  5HQX A;  2YVS A;  3TSJ A;  2EXR A;  3DED A;  2VFT A;  2AXR A;  5FXD A;  2W55 A;  4PWC A;  1AHV A;  2QPM A;  3SR6 B;  2RK5 A;  2VFU A;  2PLI A;  2P4P A;  1QLT A;  3DQ0 A;  3GSY A;  3W8W A;  1N5X A;  2BVG A;  3LAE A;  3NRZ B;  3TSH A;  3FWA A;  3W8X A;  2OAI A;  2W3S A;  1WVE A;  2R2Z A;  2O3G A;  1W1J A;  2VFS A;  4PVH A;  4UD8 A;  1UXY A;  1FO4 A;  3NVV B;  2E3T A;  1W1L A;  2NQW A;  2GQT A;  1T3Q C;  2VFR A;  3PM9 A;  1F0X A;  4EC3 A;  3NS1 B;  4OAL A;  2BVF A;  1VAO A;  4JAY A;  3C0P A;  1N60 C;  1W1R A;  4PVE A;  2W54 A;  3D2H A;  1FFV C;  3AM9 A;  4DNS A;  1HSK A;  1N63 C;  3AMZ A;  3EUB 3;  1N62 C;  4HG0 A;  1W1S A;  3TX1 A;  3AN1 A;  3NVY B;  2R8D A;  5AE3 A;  4PVJ A;  1RM6 B;  2MBR A;  1N61 C;  5HHZ A;  1FIQ B;  3NVZ B;  2VAO A;  5FXE A;  2VFV A;  2BVH A;  4PWB A;  3VTE A;  4JB1 A;  4BCA A;  5AE2 A;  1WYG A;  4MLA A;  1W1O A;  5ADZ A;  2W3R A;  5HMR A;  5FXP A;  5G5H B;  3JS8 A;  1WVF A;  1W1K A;  3ETR B;  1E8G A;  1E0Y A;  1VDV A;  1FFU C;  3B9J B;  4ML8 A;  4XLO A;  2P3H A;  5D79 A;  1ZR6 A;  1DZN A;  3BW7 A;  1E8F A;  4BC9 A;  5FXF A;  4O95 A;  1JRO A;  1DIQ A;  3S1C A;  1I19 A;  2I0K A;  3S1F A;  3I99 A;  3LLB A;  3FW7 A;  1MBT A;  3S1D A;  5AE1 A;  1W1Q A;  4PVK A;  2Q4W A;  3KJM A;  1AHZ A; 
#chains in the Genus database with same CATH topology
 2PLS A;  2GQU A;  4PYT A;  5I1V A;  1JRP A;  1QLU A;  1DII A;  1N5W C;  2P13 A;  3HRD C;  3W8Z A;  4ZOH B;  3FW9 A;  1SB3 B;  2QKN A;  4PZF A;  1MBB A;  3D2D A;  3NVW B;  5G5G B;  2UUU A;  3EJE B;  2Q85 A;  3S1E A;  4BC7 A;  3FW8 A;  1E8H A;  1W1M A;  1AHU A;  1ZXI C;  4BBY A;  1V97 A;  3D2J A;  5HQX A;  5L6F A;  2YVS A;  3TSJ A;  2EXR A;  3DED A;  2VFT A;  2AXR A;  5FXD A;  2W55 A;  4PWC A;  1AHV A;  2QPM A;  3SR6 B;  2RK5 A;  2VFU A;  2PLI A;  2P4P A;  1QLT A;  3DQ0 A;  3GSY A;  3W8W A;  1N5X A;  2BVG A;  3LAE A;  2WDW A;  3NRZ B;  3TSH A;  3FWA A;  3W8X A;  2OAI A;  2W3S A;  1WVE A;  2R2Z A;  2O3G A;  1W1J A;  5I1W A;  2VFS A;  4PVH A;  4UD8 A;  1UXY A;  1FO4 A;  3NVV B;  2E3T A;  1W1L A;  2NQW A;  2GQT A;  1T3Q C;  2VFR A;  3PM9 A;  1F0X A;  4EC3 A;  3NS1 B;  4OAL A;  2BVF A;  1VAO A;  4JAY A;  3C0P A;  3HSU A;  1N60 C;  1W1R A;  4PVE A;  2W54 A;  3D2H A;  1FFV C;  3AM9 A;  4DNS A;  3RJ8 A;  1HSK A;  1N63 C;  3AMZ A;  3EUB 3;  1N62 C;  4HG0 A;  1W1S A;  3NVY B;  3AN1 A;  3TX1 A;  2R8D A;  5AE3 A;  4PVJ A;  1RM6 B;  2MBR A;  1N61 C;  5HHZ A;  1FIQ B;  3POP A;  2Y4G A;  3NVZ B;  2VAO A;  5FXE A;  3EJD B;  2VFV A;  2BVH A;  4PWB A;  2UUV A;  3VTE A;  2Y3S A;  4JB1 A;  4BCA A;  5AE2 A;  1WYG A;  4MLA A;  5AWV A;  1W1O A;  5ADZ A;  2W3R A;  3EJB B;  5FXP A;  5HMR A;  2IPI A;  5G5H B;  3JS8 A;  1WVF A;  1W1K A;  3ETR B;  2Y08 A;  1E8G A;  1E0Y A;  1VDV A;  1FFU C;  5L6G A;  5K8E A;  3B9J B;  4ML8 A;  4XLO A;  2P3H A;  2Y3R A;  5D79 A;  1ZR6 A;  3RJA A;  1DZN A;  3PQB A;  3BW7 A;  1E8F A;  4BC9 A;  5FXF A;  4O95 A;  1JRO A;  1DIQ A;  3S1C A;  1I19 A;  2I0K A;  3S1F A;  3I99 A;  3LLB A;  3FW7 A;  1MBT A;  3S1D A;  5AE1 A;  1W1Q A;  4PVK A;  2Q4W A;  3KJM A;  1AHZ A; 
#chains in the Genus database with same CATH homology
 2PLS A;  2GQU A;  4PYT A;  5I1V A;  1JRP A;  1QLU A;  1DII A;  1N5W C;  2P13 A;  3HRD C;  3W8Z A;  4ZOH B;  3FW9 A;  1SB3 B;  2QKN A;  4PZF A;  1MBB A;  3D2D A;  3NVW B;  5G5G B;  2UUU A;  2Q85 A;  3S1E A;  4BC7 A;  3FW8 A;  1E8H A;  1W1M A;  1AHU A;  1ZXI C;  4BBY A;  1V97 A;  3D2J A;  5HQX A;  5L6F A;  2YVS A;  3TSJ A;  2EXR A;  3DED A;  2VFT A;  2AXR A;  5FXD A;  2W55 A;  4PWC A;  1AHV A;  2QPM A;  3SR6 B;  2RK5 A;  2VFU A;  2PLI A;  2P4P A;  1QLT A;  3DQ0 A;  3GSY A;  3W8W A;  1N5X A;  2BVG A;  3LAE A;  2WDW A;  3NRZ B;  3TSH A;  3FWA A;  3W8X A;  2OAI A;  2W3S A;  1WVE A;  2R2Z A;  2O3G A;  1W1J A;  5I1W A;  2VFS A;  4PVH A;  4UD8 A;  1UXY A;  1FO4 A;  3NVV B;  2E3T A;  1W1L A;  2NQW A;  2GQT A;  1T3Q C;  2VFR A;  3PM9 A;  1F0X A;  4EC3 A;  3NS1 B;  4OAL A;  2BVF A;  1VAO A;  4JAY A;  3C0P A;  3HSU A;  1N60 C;  1W1R A;  4PVE A;  2W54 A;  3D2H A;  1FFV C;  3AM9 A;  4DNS A;  3RJ8 A;  1HSK A;  1N63 C;  3AMZ A;  3EUB 3;  1N62 C;  4HG0 A;  1W1S A;  3TX1 A;  3AN1 A;  3NVY B;  2R8D A;  5AE3 A;  4PVJ A;  1RM6 B;  2MBR A;  1N61 C;  5HHZ A;  1FIQ B;  3POP A;  2Y4G A;  3NVZ B;  2VAO A;  5FXE A;  2VFV A;  2BVH A;  4PWB A;  2UUV A;  3VTE A;  2Y3S A;  4JB1 A;  4BCA A;  5AE2 A;  1WYG A;  4MLA A;  5AWV A;  1W1O A;  5ADZ A;  2W3R A;  5HMR A;  5FXP A;  2IPI A;  5G5H B;  3JS8 A;  1WVF A;  1W1K A;  3ETR B;  2Y08 A;  1E8G A;  1E0Y A;  1VDV A;  1FFU C;  5L6G A;  5K8E A;  3B9J B;  4ML8 A;  4XLO A;  2P3H A;  2Y3R A;  5D79 A;  1ZR6 A;  3RJA A;  1DZN A;  3PQB A;  3BW7 A;  1E8F A;  4BC9 A;  5FXF A;  4O95 A;  1JRO A;  1DIQ A;  3S1C A;  1I19 A;  2I0K A;  3S1F A;  3I99 A;  3LLB A;  3FW7 A;  1MBT A;  3S1D A;  5AE1 A;  1W1Q A;  4PVK A;  2Q4W A;  3KJM A;  1AHZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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