2VAOA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase in complex with isoeugenol
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
555
structure length
555
Chain Sequence
b'EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISSKDQIVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords VANILLYL-ALCOHOL OXIDASE
molecule tags Flavoenzyme
publication title Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
pubmed doi rcsb
total genus 161
structure length 555
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 1997-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 2vaoA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2vaoA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2vaoA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 2vaoA03
2R8DA 3TSJA 1N62C 3PM9A 4PZFA 1E0YA 3W8XA 2W3RA 4BC9A 2W3SA 3LAEA 4PWBA 5AE3A 4BC7A 1T3QC 4BCAA 1DIQA 2Q4WA 2PLSA 3KJMA 1QLUA 4UD8A 3W8ZA 1N5XA 2GQUA 2YVSA 1W1KA 3DQ0A 3GSYA 2P4PA 4OALA 2RK5A 2OAIA 5AE2A 4O95A 3LLBA 4MLAA 3SR6B 1JROA 3TX1A 2VFSA 1F0XA 3S1DA 1AHVA 1FFUC 3TSHA 1FIQB 1AHZA 5FXDA 4DNSA 1W1LA 5FXPA 3ETRB 5D79A 3NRZB 1JRPA 2VFUA 3JS8A 3FWAA 4XLOA 5HMRA 2P13A 2EXRA 2E3TA 1MBBA 2O3GA 3NS1B 2VFVA 1N5WC 3S1FA 3DEDA 1N60C 3AMZA 3C0PA 1SB3B 3NVYB 5HHZA 1N61C 2VAOA 4PYTA 4PVJA 4EC3A 3HRDC 3AM9A 5HQXA 4PVEA 2VFRA 5G5HB 1DIIA 5ADZA 4PVKA 1N63C 4JAYA 1V97A 1VAOA 4HG0A 3S1CA 1E8HA 1W1OA 1FO4A 3NVVB 3FW8A 1UXYA 2BVGA 2BVHA 3I99A 4BBYA 3NVZB 2MBRA 2AXRA 4JB1A 2PLIA 3S1EA 1W1SA 1QLTA 1ZR6A 2QPMA 3AN1A 3FW9A 1ZXIC 1HSKA 2BVFA 3D2DA 1DZNA 2QKNA 1E8FA 1E8GA 3VTEA 5FXFA 3NVWB 1VDVA 2W54A 1WVFA 4ZOHB 1MBTA 3FW7A 3D2HA 4ML8A 2GQTA 1WYGA 1W1QA 3W8WA 1FFVC 2R2ZA 3B9JB 5AE1A 3D2JA 1AHUA 4PVHA 3BW7A 1W1MA 2P3HA 2Q85A 1I19A 2NQWA 2I0KA 5FXEA 1W1JA 2VFTA 5G5GB 2W55A 3EUB3 4PWCA 1WVEA 1RM6B 1W1RA
chains in the Genus database with same CATH superfamily
2R8DA 3TSJA 1N62C 3PM9A 2UUVA 4PZFA 1E0YA 2Y08A 3W8XA 2W3RA 4BC9A 2W3SA 3LAEA 4PWBA 5AE3A 4BC7A 1T3QC 3EJEB 4BCAA 2UUUA 1DIQA 2Q4WA 2PLSA 3KJMA 1QLUA 3EJDB 4UD8A 2IPIA 3W8ZA 1N5XA 2GQUA 2YVSA 1W1KA 3DQ0A 3GSYA 2P4PA 4OALA 2RK5A 2OAIA 5AE2A 4O95A 3LLBA 4MLAA 3SR6B 1JROA 3TX1A 2VFSA 1F0XA 3S1DA 3POPA 2Y4GA 3HSUA 1AHVA 1FFUC 3TSHA 1FIQB 1AHZA 5FXDA 4DNSA 1W1LA 5FXPA 3ETRB 5D79A 3NRZB 1JRPA 2VFUA 3JS8A 3FWAA 4XLOA 5HMRA 2P13A 5I1VA 5K8EA 2EXRA 2E3TA 1MBBA 2O3GA 3NS1B 2VFVA 1N5WC 3S1FA 3DEDA 1N60C 3AMZA 5AWVA 3C0PA 1SB3B 3NVYB 5HHZA 1N61C 2VAOA 4PYTA 4PVJA 4EC3A 3HRDC 3AM9A 5HQXA 4PVEA 2VFRA 5G5HB 1DIIA 5ADZA 4PVKA 1N63C 4JAYA 1V97A 1VAOA 4HG0A 3S1CA 1E8HA 1W1OA 3NVVB 1FO4A 3FW8A 1UXYA 2BVGA 2BVHA 3I99A 2WDWA 4BBYA 3RJAA 3NVZB 2MBRA 2AXRA 5I1WA 4JB1A 2PLIA 3S1EA 1W1SA 1QLTA 1ZR6A 2QPMA 3AN1A 3EJBB 3FW9A 1ZXIC 1HSKA 2BVFA 3D2DA 1DZNA 5L6GA 2QKNA 1E8FA 1E8GA 3VTEA 5FXFA 3NVWB 1VDVA 2W54A 1WVFA 4ZOHB 1MBTA 3FW7A 3D2HA 4ML8A 2GQTA 1WYGA 1W1QA 3W8WA 1FFVC 2R2ZA 3PQBA 3B9JB 5AE1A 3D2JA 1AHUA 2Y3RA 4PVHA 3BW7A 3RJ8A 1W1MA 2P3HA 2Y3SA 2Q85A 1I19A 2NQWA 2I0KA 5FXEA 1W1JA 5L6FA 2VFTA 5G5GB 2W55A 3EUB3 4PWCA 1WVEA 1RM6B 1W1RA
chains in the Genus database with same CATH topology
2R8DA 3TSJA 1N62C 3PM9A 2UUVA 4PZFA 1E0YA 2Y08A 3W8XA 2W3RA 4BC9A 2W3SA 3LAEA 4PWBA 5AE3A 4BC7A 1T3QC 4BCAA 2UUUA 1DIQA 2Q4WA 2PLSA 3KJMA 1QLUA 4UD8A 2IPIA 3W8ZA 1N5XA 2GQUA 2YVSA 1W1KA 3DQ0A 3GSYA 2P4PA 4OALA 2RK5A 2OAIA 5AE2A 4O95A 3LLBA 4MLAA 3SR6B 1JROA 3TX1A 2VFSA 1F0XA 3S1DA 3POPA 2Y4GA 3HSUA 1AHVA 1FFUC 3TSHA 1FIQB 1AHZA 5FXDA 4DNSA 1W1LA 5FXPA 3ETRB 5D79A 3NRZB 1JRPA 2VFUA 3JS8A 3FWAA 4XLOA 5HMRA 2P13A 5I1VA 5K8EA 2EXRA 2E3TA 1MBBA 2O3GA 3NS1B 2VFVA 1N5WC 3S1FA 3DEDA 1N60C 3AMZA 5AWVA 3C0PA 1SB3B 3NVYB 5HHZA 1N61C 2VAOA 4PYTA 4PVJA 4EC3A 3HRDC 3AM9A 5HQXA 4PVEA 2VFRA 5G5HB 1DIIA 5ADZA 4PVKA 1N63C 4JAYA 1V97A 1VAOA 4HG0A 3S1CA 1E8HA 1W1OA 1FO4A 3NVVB 3FW8A 1UXYA 2BVGA 2BVHA 3I99A 2WDWA 4BBYA 3RJAA 3NVZB 2MBRA 2AXRA 5I1WA 4JB1A 2PLIA 3S1EA 1W1SA 1QLTA 1ZR6A 2QPMA 3AN1A 3FW9A 1ZXIC 1HSKA 2BVFA 3D2DA 1DZNA 5L6GA 2QKNA 1E8FA 1E8GA 3VTEA 5FXFA 3NVWB 1VDVA 2W54A 1WVFA 4ZOHB 1MBTA 3FW7A 3D2HA 4ML8A 2GQTA 1WYGA 1W1QA 3W8WA 1FFVC 2R2ZA 3PQBA 3B9JB 5AE1A 3D2JA 1AHUA 2Y3RA 4PVHA 3BW7A 3RJ8A 1W1MA 2P3HA 2Y3SA 2Q85A 1I19A 2NQWA 2I0KA 5FXEA 1W1JA 5L6FA 2VFTA 5G5GB 2W55A 3EUB3 4PWCA 1WVEA 1RM6B 1W1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R8D A;  3TSJ A;  1N62 C;  3PM9 A;  4PZF A;  1E0Y A;  3W8X A;  2W3R A;  4BC9 A;  2W3S A;  3LAE A;  4PWB A;  5AE3 A;  4BC7 A;  1T3Q C;  4BCA A;  1DIQ A;  2Q4W A;  2PLS A;  3KJM A;  1QLU A;  4UD8 A;  3W8Z A;  1N5X A;  2GQU A;  2YVS A;  1W1K A;  3DQ0 A;  3GSY A;  2P4P A;  4OAL A;  2RK5 A;  2OAI A;  5AE2 A;  4O95 A;  3LLB A;  4MLA A;  3SR6 B;  1JRO A;  3TX1 A;  2VFS A;  1F0X A;  3S1D A;  1AHV A;  1FFU C;  3TSH A;  1FIQ B;  1AHZ A;  5FXD A;  4DNS A;  1W1L A;  5FXP A;  3ETR B;  5D79 A;  3NRZ B;  1JRP A;  2VFU A;  3JS8 A;  3FWA A;  4XLO A;  5HMR A;  2P13 A;  2EXR A;  2E3T A;  1MBB A;  2O3G A;  3NS1 B;  2VFV A;  1N5W C;  3S1F A;  3DED A;  1N60 C;  3AMZ A;  3C0P A;  1SB3 B;  3NVY B;  5HHZ A;  1N61 C;  2VAO A;  4PYT A;  4PVJ A;  4EC3 A;  3HRD C;  3AM9 A;  5HQX A;  4PVE A;  2VFR A;  5G5H B;  1DII A;  5ADZ A;  4PVK A;  1N63 C;  4JAY A;  1V97 A;  1VAO A;  4HG0 A;  3S1C A;  1E8H A;  1W1O A;  1FO4 A;  3NVV B;  3FW8 A;  1UXY A;  2BVG A;  2BVH A;  3I99 A;  4BBY A;  3NVZ B;  2MBR A;  2AXR A;  4JB1 A;  2PLI A;  3S1E A;  1W1S A;  1QLT A;  1ZR6 A;  2QPM A;  3AN1 A;  3FW9 A;  1ZXI C;  1HSK A;  2BVF A;  3D2D A;  1DZN A;  2QKN A;  1E8F A;  1E8G A;  3VTE A;  5FXF A;  3NVW B;  1VDV A;  2W54 A;  1WVF A;  4ZOH B;  1MBT A;  3FW7 A;  3D2H A;  4ML8 A;  2GQT A;  1WYG A;  1W1Q A;  3W8W A;  1FFV C;  2R2Z A;  3B9J B;  5AE1 A;  3D2J A;  1AHU A;  4PVH A;  3BW7 A;  1W1M A;  2P3H A;  2Q85 A;  1I19 A;  2NQW A;  2I0K A;  5FXE A;  1W1J A;  2VFT A;  5G5G B;  2W55 A;  3EUB 3;  4PWC A;  1WVE A;  1RM6 B;  1W1R A; 
#chains in the Genus database with same CATH topology
 2R8D A;  3TSJ A;  1N62 C;  3PM9 A;  2UUV A;  4PZF A;  1E0Y A;  2Y08 A;  3W8X A;  2W3R A;  4BC9 A;  2W3S A;  3LAE A;  4PWB A;  5AE3 A;  4BC7 A;  1T3Q C;  3EJE B;  4BCA A;  2UUU A;  1DIQ A;  2Q4W A;  2PLS A;  3KJM A;  1QLU A;  3EJD B;  4UD8 A;  2IPI A;  3W8Z A;  1N5X A;  2GQU A;  2YVS A;  1W1K A;  3DQ0 A;  3GSY A;  2P4P A;  4OAL A;  2RK5 A;  2OAI A;  5AE2 A;  4O95 A;  3LLB A;  4MLA A;  3SR6 B;  1JRO A;  3TX1 A;  2VFS A;  1F0X A;  3S1D A;  3POP A;  2Y4G A;  3HSU A;  1AHV A;  1FFU C;  3TSH A;  1FIQ B;  1AHZ A;  5FXD A;  4DNS A;  1W1L A;  5FXP A;  3ETR B;  5D79 A;  3NRZ B;  1JRP A;  2VFU A;  3JS8 A;  3FWA A;  4XLO A;  5HMR A;  2P13 A;  5I1V A;  5K8E A;  2EXR A;  2E3T A;  1MBB A;  2O3G A;  3NS1 B;  2VFV A;  1N5W C;  3S1F A;  3DED A;  1N60 C;  3AMZ A;  5AWV A;  3C0P A;  1SB3 B;  3NVY B;  5HHZ A;  1N61 C;  2VAO A;  4PYT A;  4PVJ A;  4EC3 A;  3HRD C;  3AM9 A;  5HQX A;  4PVE A;  2VFR A;  5G5H B;  1DII A;  5ADZ A;  4PVK A;  1N63 C;  4JAY A;  1V97 A;  1VAO A;  4HG0 A;  3S1C A;  1E8H A;  1W1O A;  3NVV B;  1FO4 A;  3FW8 A;  1UXY A;  2BVG A;  2BVH A;  3I99 A;  2WDW A;  4BBY A;  3RJA A;  3NVZ B;  2MBR A;  2AXR A;  5I1W A;  4JB1 A;  2PLI A;  3S1E A;  1W1S A;  1QLT A;  1ZR6 A;  2QPM A;  3AN1 A;  3EJB B;  3FW9 A;  1ZXI C;  1HSK A;  2BVF A;  3D2D A;  1DZN A;  5L6G A;  2QKN A;  1E8F A;  1E8G A;  3VTE A;  5FXF A;  3NVW B;  1VDV A;  2W54 A;  1WVF A;  4ZOH B;  1MBT A;  3FW7 A;  3D2H A;  4ML8 A;  2GQT A;  1WYG A;  1W1Q A;  3W8W A;  1FFV C;  2R2Z A;  3PQB A;  3B9J B;  5AE1 A;  3D2J A;  1AHU A;  2Y3R A;  4PVH A;  3BW7 A;  3RJ8 A;  1W1M A;  2P3H A;  2Y3S A;  2Q85 A;  1I19 A;  2NQW A;  2I0K A;  5FXE A;  1W1J A;  5L6F A;  2VFT A;  5G5G B;  2W55 A;  3EUB 3;  4PWC A;  1WVE A;  1RM6 B;  1W1R A; 
#chains in the Genus database with same CATH homology
 2R8D A;  3TSJ A;  1N62 C;  3PM9 A;  2UUV A;  4PZF A;  1E0Y A;  2Y08 A;  3W8X A;  2W3R A;  4BC9 A;  2W3S A;  3LAE A;  4PWB A;  5AE3 A;  4BC7 A;  1T3Q C;  4BCA A;  2UUU A;  1DIQ A;  2Q4W A;  2PLS A;  3KJM A;  1QLU A;  4UD8 A;  2IPI A;  3W8Z A;  1N5X A;  2GQU A;  2YVS A;  1W1K A;  3DQ0 A;  3GSY A;  2P4P A;  4OAL A;  2RK5 A;  2OAI A;  5AE2 A;  4O95 A;  3LLB A;  4MLA A;  3SR6 B;  1JRO A;  3TX1 A;  2VFS A;  1F0X A;  3S1D A;  3POP A;  2Y4G A;  3HSU A;  1AHV A;  1FFU C;  3TSH A;  1FIQ B;  1AHZ A;  5FXD A;  4DNS A;  1W1L A;  5FXP A;  3ETR B;  5D79 A;  3NRZ B;  1JRP A;  2VFU A;  3JS8 A;  3FWA A;  4XLO A;  5HMR A;  2P13 A;  5I1V A;  5K8E A;  2EXR A;  2E3T A;  1MBB A;  2O3G A;  3NS1 B;  2VFV A;  1N5W C;  3S1F A;  3DED A;  1N60 C;  3AMZ A;  5AWV A;  3C0P A;  1SB3 B;  3NVY B;  5HHZ A;  1N61 C;  2VAO A;  4PYT A;  4PVJ A;  4EC3 A;  3HRD C;  3AM9 A;  5HQX A;  4PVE A;  2VFR A;  5G5H B;  1DII A;  5ADZ A;  4PVK A;  1N63 C;  4JAY A;  1V97 A;  1VAO A;  4HG0 A;  3S1C A;  1E8H A;  1W1O A;  1FO4 A;  3NVV B;  3FW8 A;  1UXY A;  2BVG A;  2BVH A;  3I99 A;  2WDW A;  4BBY A;  3RJA A;  3NVZ B;  2MBR A;  2AXR A;  5I1W A;  4JB1 A;  2PLI A;  3S1E A;  1W1S A;  1QLT A;  1ZR6 A;  2QPM A;  3AN1 A;  3FW9 A;  1ZXI C;  1HSK A;  2BVF A;  3D2D A;  1DZN A;  5L6G A;  2QKN A;  1E8F A;  1E8G A;  3VTE A;  5FXF A;  3NVW B;  1VDV A;  2W54 A;  1WVF A;  4ZOH B;  1MBT A;  3FW7 A;  3D2H A;  4ML8 A;  2GQT A;  1WYG A;  1W1Q A;  3W8W A;  1FFV C;  2R2Z A;  3PQB A;  3B9J B;  5AE1 A;  3D2J A;  1AHU A;  2Y3R A;  4PVH A;  3BW7 A;  3RJ8 A;  1W1M A;  2P3H A;  2Y3S A;  2Q85 A;  1I19 A;  2NQW A;  2I0K A;  5FXE A;  1W1J A;  5L6F A;  2VFT A;  5G5G B;  2W55 A;  3EUB 3;  4PWC A;  1WVE A;  1RM6 B;  1W1R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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