4XLOA

Crystal structure of encm (crystallized with 4 mm nadph)
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
458
structure length
458
Chain Sequence
QLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARCTSTPDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIKVSRRLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFGWLSRKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVVTAFEFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLRLAPPLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKATLPYRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPFTQLELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWAREGYRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTNLFRLNQNIPPS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Streptomyces maritimus
molecule keywords FAD-dependent oxygenase EncM
total genus 141
structure length 458
sequence length 458
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2015-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4xloA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4xloA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 4xloA03
5K8EA 1AHUA 3SR6B 3LAEA 2QKNA 4UD8A 4BC9A 5FXPA 4PVKA 3D2HA 2PLIA 5G5GB 1FIQB 1AHVA 2VFRA 3TSHA 2NQWA 4HG0A 2P13A 5I1WA 2W54A 2P4PA 1DIQA 3DQ0A 1DIIA 3VTEA 3BW7A 5AE2A 1FFVC 1I19A 3PQBA 5FXDA 1N5WC 2VFVA 1WVEA 1N63C 1AHZA 2QPMA 3HSUA 3POPA 1E8GA 1N5XA 1N62C 4BBYA 1FO4A 5AE1A 2PLSA 5HQXA 5AWVA 5AE3A 1MBTA 3NVYB 3LLBA 2E3TA 3C0PA 2Y3SA 3ETRB 4OALA 1MBBA 1ZR6A 1V97A 3RJ8A 5HHZA 1ZXIC 4PZFA 1T3QC 3JS8A 3GSYA 3DEDA 1VDVA 3B9JB 3D2DA 4PWBA 1W1MA 4PYTA 4BCAA 1E8FA 2I0KA 3FWAA 5FXFA 5I1VA 2VAOA 2BVGA 1F0XA 5FXEA 1W1SA 4PWCA 2Y08A 1UXYA 3NVVB 3I99A 3D2JA 3W8WA 3FW7A 2OAIA 2BVHA 1W1KA 3NVZB 1W1OA 2MBRA 3AMZA 3NVWB 1JROA 5G5HB 2WDWA 1SB3B 1E0YA 1N61C 4O95A 3AN1A 2AXRA 4XLOA 3TSJA 1RM6B 2R8DA 2IPIA 1WVFA 4BC7A 2W3SA 1HSKA 2VFUA 1QLTA 5HMRA 1W1LA 2VFSA 3EUB3 2EXRA 2GQTA 2W3RA 3HRDC 2RK5A 1DZNA 3S1FA 1FFUC 4EC3A 4JB1A 5D79A 3W8XA 2YVSA 1W1QA 3NRZB 3W8ZA 1QLUA 2BVFA 2Q4WA 3S1DA 4DNSA 4ML8A 5L6FA 3S1CA 2O3GA 1N60C 1E8HA 1VAOA 1W1RA 3AM9A 3KJMA 4JAYA 4MLAA 4ZOHB 2Y3RA 1W1JA 2P3HA 2R2ZA 2GQUA 2Y4GA 4PVHA 3PM9A 3FW9A 2VFTA 4PVEA 3RJAA 1JRPA 1WYGA 4PVJA 3NS1B 5ADZA 2Q85A 3S1EA 2W55A 3TX1A 5L6GA 3FW8A
chains in the Genus database with same CATH superfamily
5K8EA 1AHUA 3SR6B 3LAEA 2QKNA 4UD8A 4BC9A 5FXPA 4PVKA 3D2HA 2PLIA 5G5GB 1FIQB 1AHVA 2VFRA 3TSHA 2NQWA 4HG0A 2P13A 5I1WA 2W54A 3EJEB 3EJBB 2P4PA 1DIQA 3DQ0A 1DIIA 3VTEA 3BW7A 5AE2A 1FFVC 1I19A 3PQBA 5FXDA 1N5WC 2VFVA 3EJDB 1WVEA 1N63C 1AHZA 2QPMA 3HSUA 3POPA 1E8GA 1N5XA 1N62C 4BBYA 1FO4A 5AE1A 2PLSA 5HQXA 5AWVA 3NVYB 1MBTA 5AE3A 3LLBA 2E3TA 3C0PA 2Y3SA 3ETRB 4OALA 1MBBA 1ZR6A 1V97A 3RJ8A 5HHZA 1ZXIC 4PZFA 1T3QC 3JS8A 3GSYA 3DEDA 1VDVA 3B9JB 3D2DA 4PWBA 1W1MA 4PYTA 4BCAA 1E8FA 2I0KA 3FWAA 5FXFA 5I1VA 2VAOA 2BVGA 1F0XA 5FXEA 1W1SA 4PWCA 2Y08A 1UXYA 3NVVB 3I99A 3D2JA 3W8WA 3FW7A 2OAIA 2BVHA 1W1KA 3NVZB 1W1OA 2MBRA 3AMZA 3NVWB 1JROA 5G5HB 2WDWA 1SB3B 1E0YA 1N61C 4O95A 3AN1A 2AXRA 4XLOA 3TSJA 1RM6B 2IPIA 2R8DA 2UUUA 1WVFA 4BC7A 2W3SA 1HSKA 2VFUA 1QLTA 5HMRA 1W1LA 2VFSA 3EUB3 2EXRA 2GQTA 2W3RA 3HRDC 2RK5A 1DZNA 3S1FA 1FFUC 4EC3A 2UUVA 4JB1A 5D79A 3W8XA 2YVSA 1W1QA 3NRZB 3W8ZA 1QLUA 2BVFA 2Q4WA 3S1DA 4DNSA 4ML8A 5L6FA 3S1CA 2O3GA 1N60C 1E8HA 1VAOA 1W1RA 3AM9A 3KJMA 4JAYA 4MLAA 4ZOHB 2Y3RA 1W1JA 2P3HA 2R2ZA 2GQUA 2Y4GA 4PVHA 3PM9A 3FW9A 2VFTA 4PVEA 3RJAA 1JRPA 1WYGA 4PVJA 3NS1B 5ADZA 2Q85A 3S1EA 2W55A 3TX1A 5L6GA 3FW8A
chains in the Genus database with same CATH topology
5K8EA 1AHUA 3SR6B 3LAEA 2QKNA 4UD8A 4BC9A 5FXPA 4PVKA 3D2HA 2PLIA 5G5GB 1FIQB 1AHVA 2VFRA 3TSHA 2NQWA 4HG0A 2P13A 5I1WA 2W54A 2P4PA 1DIQA 3DQ0A 1DIIA 3VTEA 3BW7A 5AE2A 1FFVC 1I19A 3PQBA 5FXDA 1N5WC 2VFVA 1WVEA 1N63C 1AHZA 2QPMA 3HSUA 3POPA 1E8GA 1N5XA 1N62C 4BBYA 1FO4A 5AE1A 2PLSA 5HQXA 5AWVA 5AE3A 1MBTA 3NVYB 3LLBA 2E3TA 3C0PA 2Y3SA 3ETRB 4OALA 1MBBA 1ZR6A 1V97A 3RJ8A 5HHZA 1ZXIC 4PZFA 1T3QC 3JS8A 3GSYA 3DEDA 1VDVA 3B9JB 3D2DA 4PWBA 1W1MA 4PYTA 4BCAA 1E8FA 2I0KA 3FWAA 5FXFA 5I1VA 2VAOA 2BVGA 1F0XA 5FXEA 1W1SA 4PWCA 2Y08A 1UXYA 3NVVB 3I99A 3D2JA 3W8WA 3FW7A 2OAIA 2BVHA 1W1KA 3NVZB 1W1OA 2MBRA 3AMZA 3NVWB 1JROA 5G5HB 2WDWA 1SB3B 1E0YA 1N61C 4O95A 3AN1A 2AXRA 4XLOA 3TSJA 1RM6B 2IPIA 2R8DA 2UUUA 1WVFA 4BC7A 2W3SA 1HSKA 2VFUA 1QLTA 5HMRA 1W1LA 2VFSA 3EUB3 2EXRA 2GQTA 2W3RA 3HRDC 2RK5A 1DZNA 3S1FA 1FFUC 4EC3A 2UUVA 4JB1A 5D79A 3W8XA 2YVSA 1W1QA 3NRZB 3W8ZA 1QLUA 2BVFA 2Q4WA 3S1DA 4DNSA 4ML8A 5L6FA 3S1CA 2O3GA 1N60C 1E8HA 1VAOA 1W1RA 3AM9A 3KJMA 4JAYA 4MLAA 4ZOHB 2Y3RA 1W1JA 2P3HA 2R2ZA 2GQUA 2Y4GA 4PVHA 3PM9A 3FW9A 2VFTA 4PVEA 3RJAA 1JRPA 1WYGA 4PVJA 3NS1B 5ADZA 2Q85A 3S1EA 2W55A 3TX1A 5L6GA 3FW8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5K8E A;  1AHU A;  3SR6 B;  3LAE A;  2QKN A;  4UD8 A;  4BC9 A;  5FXP A;  4PVK A;  3D2H A;  2PLI A;  5G5G B;  1FIQ B;  1AHV A;  2VFR A;  3TSH A;  2NQW A;  4HG0 A;  2P13 A;  5I1W A;  2W54 A;  2P4P A;  1DIQ A;  3DQ0 A;  1DII A;  3VTE A;  3BW7 A;  5AE2 A;  1FFV C;  1I19 A;  3PQB A;  5FXD A;  1N5W C;  2VFV A;  1WVE A;  1N63 C;  1AHZ A;  2QPM A;  3HSU A;  3POP A;  1E8G A;  1N5X A;  1N62 C;  4BBY A;  1FO4 A;  5AE1 A;  2PLS A;  5HQX A;  5AWV A;  5AE3 A;  1MBT A;  3NVY B;  3LLB A;  2E3T A;  3C0P A;  2Y3S A;  3ETR B;  4OAL A;  1MBB A;  1ZR6 A;  1V97 A;  3RJ8 A;  5HHZ A;  1ZXI C;  4PZF A;  1T3Q C;  3JS8 A;  3GSY A;  3DED A;  1VDV A;  3B9J B;  3D2D A;  4PWB A;  1W1M A;  4PYT A;  4BCA A;  1E8F A;  2I0K A;  3FWA A;  5FXF A;  5I1V A;  2VAO A;  2BVG A;  1F0X A;  5FXE A;  1W1S A;  4PWC A;  2Y08 A;  1UXY A;  3NVV B;  3I99 A;  3D2J A;  3W8W A;  3FW7 A;  2OAI A;  2BVH A;  1W1K A;  3NVZ B;  1W1O A;  2MBR A;  3AMZ A;  3NVW B;  1JRO A;  5G5H B;  2WDW A;  1SB3 B;  1E0Y A;  1N61 C;  4O95 A;  3AN1 A;  2AXR A;  4XLO A;  3TSJ A;  1RM6 B;  2R8D A;  2IPI A;  1WVF A;  4BC7 A;  2W3S A;  1HSK A;  2VFU A;  1QLT A;  5HMR A;  1W1L A;  2VFS A;  3EUB 3;  2EXR A;  2GQT A;  2W3R A;  3HRD C;  2RK5 A;  1DZN A;  3S1F A;  1FFU C;  4EC3 A;  4JB1 A;  5D79 A;  3W8X A;  2YVS A;  1W1Q A;  3NRZ B;  3W8Z A;  1QLU A;  2BVF A;  2Q4W A;  3S1D A;  4DNS A;  4ML8 A;  5L6F A;  3S1C A;  2O3G A;  1N60 C;  1E8H A;  1VAO A;  1W1R A;  3AM9 A;  3KJM A;  4JAY A;  4MLA A;  4ZOH B;  2Y3R A;  1W1J A;  2P3H A;  2R2Z A;  2GQU A;  2Y4G A;  4PVH A;  3PM9 A;  3FW9 A;  2VFT A;  4PVE A;  3RJA A;  1JRP A;  1WYG A;  4PVJ A;  3NS1 B;  5ADZ A;  2Q85 A;  3S1E A;  2W55 A;  3TX1 A;  5L6G A;  3FW8 A; 
#chains in the Genus database with same CATH topology
 5K8E A;  1AHU A;  3SR6 B;  3LAE A;  2QKN A;  4UD8 A;  4BC9 A;  5FXP A;  4PVK A;  3D2H A;  2PLI A;  5G5G B;  1FIQ B;  1AHV A;  2VFR A;  3TSH A;  2NQW A;  4HG0 A;  2P13 A;  5I1W A;  2W54 A;  3EJE B;  3EJB B;  2P4P A;  1DIQ A;  3DQ0 A;  1DII A;  3VTE A;  3BW7 A;  5AE2 A;  1FFV C;  1I19 A;  3PQB A;  5FXD A;  1N5W C;  2VFV A;  3EJD B;  1WVE A;  1N63 C;  1AHZ A;  2QPM A;  3HSU A;  3POP A;  1E8G A;  1N5X A;  1N62 C;  4BBY A;  1FO4 A;  5AE1 A;  2PLS A;  5HQX A;  5AWV A;  3NVY B;  1MBT A;  5AE3 A;  3LLB A;  2E3T A;  3C0P A;  2Y3S A;  3ETR B;  4OAL A;  1MBB A;  1ZR6 A;  1V97 A;  3RJ8 A;  5HHZ A;  1ZXI C;  4PZF A;  1T3Q C;  3JS8 A;  3GSY A;  3DED A;  1VDV A;  3B9J B;  3D2D A;  4PWB A;  1W1M A;  4PYT A;  4BCA A;  1E8F A;  2I0K A;  3FWA A;  5FXF A;  5I1V A;  2VAO A;  2BVG A;  1F0X A;  5FXE A;  1W1S A;  4PWC A;  2Y08 A;  1UXY A;  3NVV B;  3I99 A;  3D2J A;  3W8W A;  3FW7 A;  2OAI A;  2BVH A;  1W1K A;  3NVZ B;  1W1O A;  2MBR A;  3AMZ A;  3NVW B;  1JRO A;  5G5H B;  2WDW A;  1SB3 B;  1E0Y A;  1N61 C;  4O95 A;  3AN1 A;  2AXR A;  4XLO A;  3TSJ A;  1RM6 B;  2IPI A;  2R8D A;  2UUU A;  1WVF A;  4BC7 A;  2W3S A;  1HSK A;  2VFU A;  1QLT A;  5HMR A;  1W1L A;  2VFS A;  3EUB 3;  2EXR A;  2GQT A;  2W3R A;  3HRD C;  2RK5 A;  1DZN A;  3S1F A;  1FFU C;  4EC3 A;  2UUV A;  4JB1 A;  5D79 A;  3W8X A;  2YVS A;  1W1Q A;  3NRZ B;  3W8Z A;  1QLU A;  2BVF A;  2Q4W A;  3S1D A;  4DNS A;  4ML8 A;  5L6F A;  3S1C A;  2O3G A;  1N60 C;  1E8H A;  1VAO A;  1W1R A;  3AM9 A;  3KJM A;  4JAY A;  4MLA A;  4ZOH B;  2Y3R A;  1W1J A;  2P3H A;  2R2Z A;  2GQU A;  2Y4G A;  4PVH A;  3PM9 A;  3FW9 A;  2VFT A;  4PVE A;  3RJA A;  1JRP A;  1WYG A;  4PVJ A;  3NS1 B;  5ADZ A;  2Q85 A;  3S1E A;  2W55 A;  3TX1 A;  5L6G A;  3FW8 A; 
#chains in the Genus database with same CATH homology
 5K8E A;  1AHU A;  3SR6 B;  3LAE A;  2QKN A;  4UD8 A;  4BC9 A;  5FXP A;  4PVK A;  3D2H A;  2PLI A;  5G5G B;  1FIQ B;  1AHV A;  2VFR A;  3TSH A;  2NQW A;  4HG0 A;  2P13 A;  5I1W A;  2W54 A;  2P4P A;  1DIQ A;  3DQ0 A;  1DII A;  3VTE A;  3BW7 A;  5AE2 A;  1FFV C;  1I19 A;  3PQB A;  5FXD A;  1N5W C;  2VFV A;  1WVE A;  1N63 C;  1AHZ A;  2QPM A;  3HSU A;  3POP A;  1E8G A;  1N5X A;  1N62 C;  4BBY A;  1FO4 A;  5AE1 A;  2PLS A;  5HQX A;  5AWV A;  5AE3 A;  1MBT A;  3NVY B;  3LLB A;  2E3T A;  3C0P A;  2Y3S A;  3ETR B;  4OAL A;  1MBB A;  1ZR6 A;  1V97 A;  3RJ8 A;  5HHZ A;  1ZXI C;  4PZF A;  1T3Q C;  3JS8 A;  3GSY A;  3DED A;  1VDV A;  3B9J B;  3D2D A;  4PWB A;  1W1M A;  4PYT A;  4BCA A;  1E8F A;  2I0K A;  3FWA A;  5FXF A;  5I1V A;  2VAO A;  2BVG A;  1F0X A;  5FXE A;  1W1S A;  4PWC A;  2Y08 A;  1UXY A;  3NVV B;  3I99 A;  3D2J A;  3W8W A;  3FW7 A;  2OAI A;  2BVH A;  1W1K A;  3NVZ B;  1W1O A;  2MBR A;  3AMZ A;  3NVW B;  1JRO A;  5G5H B;  2WDW A;  1SB3 B;  1E0Y A;  1N61 C;  4O95 A;  3AN1 A;  2AXR A;  4XLO A;  3TSJ A;  1RM6 B;  2IPI A;  2R8D A;  2UUU A;  1WVF A;  4BC7 A;  2W3S A;  1HSK A;  2VFU A;  1QLT A;  5HMR A;  1W1L A;  2VFS A;  3EUB 3;  2EXR A;  2GQT A;  2W3R A;  3HRD C;  2RK5 A;  1DZN A;  3S1F A;  1FFU C;  4EC3 A;  2UUV A;  4JB1 A;  5D79 A;  3W8X A;  2YVS A;  1W1Q A;  3NRZ B;  3W8Z A;  1QLU A;  2BVF A;  2Q4W A;  3S1D A;  4DNS A;  4ML8 A;  5L6F A;  3S1C A;  2O3G A;  1N60 C;  1E8H A;  1VAO A;  1W1R A;  3AM9 A;  3KJM A;  4JAY A;  4MLA A;  4ZOH B;  2Y3R A;  1W1J A;  2P3H A;  2R2Z A;  2GQU A;  2Y4G A;  4PVH A;  3PM9 A;  3FW9 A;  2VFT A;  4PVE A;  3RJA A;  1JRP A;  1WYG A;  4PVJ A;  3NS1 B;  5ADZ A;  2Q85 A;  3S1E A;  2W55 A;  3TX1 A;  5L6G A;  3FW8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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