4XLOA

Crystal structure of encm (crystallized with 4 mm nadph)
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
458
structure length
458
Chain Sequence
QLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARCTSTPDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIKVSRRLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFGWLSRKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVVTAFEFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLRLAPPLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKATLPYRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPFTQLELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWAREGYRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTNLFRLNQNIPPS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
pubmed doi rcsb
source organism Streptomyces maritimus
molecule tags Oxidoreductase
molecule keywords FAD-dependent oxygenase EncM
total genus 141
structure length 458
sequence length 458
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2015-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4xloA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4xloA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 4xloA03
2Q4WA 2OAIA 1E8GA 5FXPA 3TX1A 2YVSA 1MBBA 1WYGA 4BBYA 4PVHA 3AM9A 3FW7A 5AWVA 1E8FA 2I0KA 4BCAA 2QPMA 1DZNA 3ETRB 4PVJA 3W8WA 3JS8A 3AMZA 2MBRA 3POPA 2W54A 2IPIA 4BC9A 1FFUC 3NVYB 2W55A 5D79A 4JB1A 5L6FA 4PZFA 1E0YA 4BC7A 1MBTA 1T3QC 2PLSA 1UXYA 2W3RA 3C0PA 5FXDA 1W1RA 2P3HA 3RJAA 1WVFA 1VDVA 2P4PA 5I1VA 1N60C 3SR6B 2PLIA 2Y08A 4XLOA 3S1FA 5AE2A 4ML8A 3BW7A 3S1CA 4EC3A 1JRPA 3LLBA 1N62C 3LAEA 1FIQB 1RM6B 2W3SA 2VFRA 3I99A 2Y3RA 5HQXA 5G5GB 4PVKA 1N5XA 3W8XA 1QLTA 2VFVA 2NQWA 4DNSA 4HG0A 1VAOA 1F0XA 3RJ8A 2AXRA 1N63C 2BVFA 1DIQA 3FW9A 1V97A 2RK5A 2BVGA 5FXFA 3VTEA 3FWAA 3KJMA 3PM9A 2R2ZA 2Y4GA 5FXEA 1W1MA 2GQTA 1JROA 5AE3A 2WDWA 2VAOA 3GSYA 5I1WA 1WVEA 2GQUA 1AHZA 1AHVA 4PWBA 3S1EA 1DIIA 4OALA 3HRDC 4ZOHB 3D2JA 2E3TA 1W1QA 4MLAA 3S1DA 3NVZB 1N61C 4JAYA 1FO4A 3NVWB 5L6GA 3TSJA 5ADZA 1W1JA 3W8ZA 3HSUA 4PWCA 1W1LA 5AE1A 3FW8A 4UD8A 2EXRA 5G5HB 3PQBA 2VFUA 1W1OA 2R8DA 1HSKA 2Y3SA 1SB3B 3NRZB 2O3GA 1QLUA 3DEDA 2Q85A 1FFVC 2VFSA 3D2HA 4O95A 1ZXIC 2VFTA 1ZR6A 4PVEA 3B9JB 2P13A 1N5WC 2QKNA 3EUB3 1AHUA 5HMRA 3D2DA 3DQ0A 1W1KA 4PYTA 5K8EA 1E8HA 3TSHA 3AN1A 2BVHA 1W1SA 3NS1B 5HHZA 3NVVB 1I19A
chains in the Genus database with same CATH superfamily
2Q4WA 2OAIA 1E8GA 5FXPA 3TX1A 2UUVA 2YVSA 1MBBA 1WYGA 4BBYA 4PVHA 3AM9A 3FW7A 5AWVA 1E8FA 2I0KA 4BCAA 2QPMA 1DZNA 3ETRB 4PVJA 3W8WA 3JS8A 3AMZA 2MBRA 3POPA 2W54A 2IPIA 4BC9A 1FFUC 3NVYB 2W55A 5D79A 4JB1A 5L6FA 4PZFA 1E0YA 4BC7A 1MBTA 1T3QC 2PLSA 1UXYA 2W3RA 3C0PA 5FXDA 1W1RA 2P3HA 3RJAA 1WVFA 1VDVA 2P4PA 5I1VA 1N60C 3SR6B 2PLIA 2Y08A 4XLOA 3S1FA 5AE2A 4ML8A 3BW7A 3EJBB 3S1CA 4EC3A 1JRPA 3LLBA 1N62C 3LAEA 1FIQB 1RM6B 2W3SA 2VFRA 3I99A 2Y3RA 5HQXA 5G5GB 4PVKA 1N5XA 3W8XA 1QLTA 2VFVA 2NQWA 4DNSA 4HG0A 1VAOA 1F0XA 3RJ8A 2AXRA 1N63C 2BVFA 1DIQA 3FW9A 1V97A 2RK5A 2BVGA 5FXFA 3VTEA 3FWAA 3KJMA 3PM9A 2R2ZA 2Y4GA 5FXEA 1W1MA 2GQTA 1JROA 5AE3A 2WDWA 2VAOA 3GSYA 5I1WA 1WVEA 2GQUA 1AHZA 1AHVA 4PWBA 3S1EA 1DIIA 4OALA 3HRDC 4ZOHB 3D2JA 2E3TA 1W1QA 4MLAA 3S1DA 3NVZB 1N61C 4JAYA 1FO4A 3NVWB 5L6GA 3TSJA 5ADZA 1W1JA 3W8ZA 3HSUA 4PWCA 1W1LA 5AE1A 3FW8A 4UD8A 2EXRA 3PQBA 5G5HB 2VFUA 1W1OA 2R8DA 1HSKA 2Y3SA 3EJEB 1SB3B 3NRZB 2UUUA 2O3GA 1QLUA 3DEDA 2Q85A 1FFVC 2VFSA 3D2HA 4O95A 1ZXIC 2VFTA 1ZR6A 4PVEA 3B9JB 2P13A 1N5WC 2QKNA 3EUB3 1AHUA 3EJDB 5HMRA 3D2DA 3DQ0A 1W1KA 4PYTA 5K8EA 1E8HA 3TSHA 3AN1A 2BVHA 1W1SA 3NS1B 5HHZA 3NVVB 1I19A
chains in the Genus database with same CATH topology
2Q4WA 2OAIA 1E8GA 5FXPA 3TX1A 2UUVA 2YVSA 1MBBA 1WYGA 4BBYA 4PVHA 3AM9A 3FW7A 5AWVA 1E8FA 2I0KA 4BCAA 2QPMA 1DZNA 3ETRB 4PVJA 3W8WA 3JS8A 3AMZA 2MBRA 3POPA 2W54A 2IPIA 4BC9A 1FFUC 3NVYB 2W55A 5D79A 4JB1A 5L6FA 4PZFA 1E0YA 4BC7A 1MBTA 1T3QC 2PLSA 1UXYA 2W3RA 3C0PA 5FXDA 1W1RA 2P3HA 3RJAA 1WVFA 1VDVA 2P4PA 5I1VA 1N60C 3SR6B 2PLIA 2Y08A 4XLOA 3S1FA 5AE2A 4ML8A 3BW7A 3S1CA 4EC3A 1JRPA 3LLBA 1N62C 3LAEA 1FIQB 1RM6B 2W3SA 2VFRA 3I99A 2Y3RA 5HQXA 5G5GB 4PVKA 1N5XA 3W8XA 1QLTA 2VFVA 2NQWA 4DNSA 4HG0A 1VAOA 1F0XA 3RJ8A 2AXRA 1N63C 2BVFA 1DIQA 3FW9A 1V97A 2RK5A 2BVGA 5FXFA 3VTEA 3FWAA 3KJMA 3PM9A 2R2ZA 2Y4GA 5FXEA 1W1MA 2GQTA 1JROA 5AE3A 2WDWA 2VAOA 3GSYA 5I1WA 1WVEA 2GQUA 1AHZA 1AHVA 4PWBA 3S1EA 1DIIA 4OALA 3HRDC 4ZOHB 3D2JA 2E3TA 1W1QA 4MLAA 3S1DA 3NVZB 1N61C 4JAYA 1FO4A 3NVWB 5L6GA 3TSJA 5ADZA 1W1JA 3W8ZA 3HSUA 4PWCA 1W1LA 5AE1A 3FW8A 4UD8A 2EXRA 3PQBA 5G5HB 2VFUA 1W1OA 2R8DA 1HSKA 2Y3SA 1SB3B 3NRZB 2UUUA 2O3GA 1QLUA 3DEDA 2Q85A 1FFVC 2VFSA 3D2HA 4O95A 1ZXIC 2VFTA 1ZR6A 4PVEA 3B9JB 2P13A 1N5WC 2QKNA 3EUB3 1AHUA 5HMRA 3D2DA 3DQ0A 1W1KA 4PYTA 5K8EA 1E8HA 3TSHA 3AN1A 2BVHA 1W1SA 3NS1B 5HHZA 3NVVB 1I19A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q4W A;  2OAI A;  1E8G A;  5FXP A;  3TX1 A;  2YVS A;  1MBB A;  1WYG A;  4BBY A;  4PVH A;  3AM9 A;  3FW7 A;  5AWV A;  1E8F A;  2I0K A;  4BCA A;  2QPM A;  1DZN A;  3ETR B;  4PVJ A;  3W8W A;  3JS8 A;  3AMZ A;  2MBR A;  3POP A;  2W54 A;  2IPI A;  4BC9 A;  1FFU C;  3NVY B;  2W55 A;  5D79 A;  4JB1 A;  5L6F A;  4PZF A;  1E0Y A;  4BC7 A;  1MBT A;  1T3Q C;  2PLS A;  1UXY A;  2W3R A;  3C0P A;  5FXD A;  1W1R A;  2P3H A;  3RJA A;  1WVF A;  1VDV A;  2P4P A;  5I1V A;  1N60 C;  3SR6 B;  2PLI A;  2Y08 A;  4XLO A;  3S1F A;  5AE2 A;  4ML8 A;  3BW7 A;  3S1C A;  4EC3 A;  1JRP A;  3LLB A;  1N62 C;  3LAE A;  1FIQ B;  1RM6 B;  2W3S A;  2VFR A;  3I99 A;  2Y3R A;  5HQX A;  5G5G B;  4PVK A;  1N5X A;  3W8X A;  1QLT A;  2VFV A;  2NQW A;  4DNS A;  4HG0 A;  1VAO A;  1F0X A;  3RJ8 A;  2AXR A;  1N63 C;  2BVF A;  1DIQ A;  3FW9 A;  1V97 A;  2RK5 A;  2BVG A;  5FXF A;  3VTE A;  3FWA A;  3KJM A;  3PM9 A;  2R2Z A;  2Y4G A;  5FXE A;  1W1M A;  2GQT A;  1JRO A;  5AE3 A;  2WDW A;  2VAO A;  3GSY A;  5I1W A;  1WVE A;  2GQU A;  1AHZ A;  1AHV A;  4PWB A;  3S1E A;  1DII A;  4OAL A;  3HRD C;  4ZOH B;  3D2J A;  2E3T A;  1W1Q A;  4MLA A;  3S1D A;  3NVZ B;  1N61 C;  4JAY A;  1FO4 A;  3NVW B;  5L6G A;  3TSJ A;  5ADZ A;  1W1J A;  3W8Z A;  3HSU A;  4PWC A;  1W1L A;  5AE1 A;  3FW8 A;  4UD8 A;  2EXR A;  5G5H B;  3PQB A;  2VFU A;  1W1O A;  2R8D A;  1HSK A;  2Y3S A;  1SB3 B;  3NRZ B;  2O3G A;  1QLU A;  3DED A;  2Q85 A;  1FFV C;  2VFS A;  3D2H A;  4O95 A;  1ZXI C;  2VFT A;  1ZR6 A;  4PVE A;  3B9J B;  2P13 A;  1N5W C;  2QKN A;  3EUB 3;  1AHU A;  5HMR A;  3D2D A;  3DQ0 A;  1W1K A;  4PYT A;  5K8E A;  1E8H A;  3TSH A;  3AN1 A;  2BVH A;  1W1S A;  3NS1 B;  5HHZ A;  3NVV B;  1I19 A; 
#chains in the Genus database with same CATH topology
 2Q4W A;  2OAI A;  1E8G A;  5FXP A;  3TX1 A;  2UUV A;  2YVS A;  1MBB A;  1WYG A;  4BBY A;  4PVH A;  3AM9 A;  3FW7 A;  5AWV A;  1E8F A;  2I0K A;  4BCA A;  2QPM A;  1DZN A;  3ETR B;  4PVJ A;  3W8W A;  3JS8 A;  3AMZ A;  2MBR A;  3POP A;  2W54 A;  2IPI A;  4BC9 A;  1FFU C;  3NVY B;  2W55 A;  5D79 A;  4JB1 A;  5L6F A;  4PZF A;  1E0Y A;  4BC7 A;  1MBT A;  1T3Q C;  2PLS A;  1UXY A;  2W3R A;  3C0P A;  5FXD A;  1W1R A;  2P3H A;  3RJA A;  1WVF A;  1VDV A;  2P4P A;  5I1V A;  1N60 C;  3SR6 B;  2PLI A;  2Y08 A;  4XLO A;  3S1F A;  5AE2 A;  4ML8 A;  3BW7 A;  3EJB B;  3S1C A;  4EC3 A;  1JRP A;  3LLB A;  1N62 C;  3LAE A;  1FIQ B;  1RM6 B;  2W3S A;  2VFR A;  3I99 A;  2Y3R A;  5HQX A;  5G5G B;  4PVK A;  1N5X A;  3W8X A;  1QLT A;  2VFV A;  2NQW A;  4DNS A;  4HG0 A;  1VAO A;  1F0X A;  3RJ8 A;  2AXR A;  1N63 C;  2BVF A;  1DIQ A;  3FW9 A;  1V97 A;  2RK5 A;  2BVG A;  5FXF A;  3VTE A;  3FWA A;  3KJM A;  3PM9 A;  2R2Z A;  2Y4G A;  5FXE A;  1W1M A;  2GQT A;  1JRO A;  5AE3 A;  2WDW A;  2VAO A;  3GSY A;  5I1W A;  1WVE A;  2GQU A;  1AHZ A;  1AHV A;  4PWB A;  3S1E A;  1DII A;  4OAL A;  3HRD C;  4ZOH B;  3D2J A;  2E3T A;  1W1Q A;  4MLA A;  3S1D A;  3NVZ B;  1N61 C;  4JAY A;  1FO4 A;  3NVW B;  5L6G A;  3TSJ A;  5ADZ A;  1W1J A;  3W8Z A;  3HSU A;  4PWC A;  1W1L A;  5AE1 A;  3FW8 A;  4UD8 A;  2EXR A;  3PQB A;  5G5H B;  2VFU A;  1W1O A;  2R8D A;  1HSK A;  2Y3S A;  3EJE B;  1SB3 B;  3NRZ B;  2UUU A;  2O3G A;  1QLU A;  3DED A;  2Q85 A;  1FFV C;  2VFS A;  3D2H A;  4O95 A;  1ZXI C;  2VFT A;  1ZR6 A;  4PVE A;  3B9J B;  2P13 A;  1N5W C;  2QKN A;  3EUB 3;  1AHU A;  3EJD B;  5HMR A;  3D2D A;  3DQ0 A;  1W1K A;  4PYT A;  5K8E A;  1E8H A;  3TSH A;  3AN1 A;  2BVH A;  1W1S A;  3NS1 B;  5HHZ A;  3NVV B;  1I19 A; 
#chains in the Genus database with same CATH homology
 2Q4W A;  2OAI A;  1E8G A;  5FXP A;  3TX1 A;  2UUV A;  2YVS A;  1MBB A;  1WYG A;  4BBY A;  4PVH A;  3AM9 A;  3FW7 A;  5AWV A;  1E8F A;  2I0K A;  4BCA A;  2QPM A;  1DZN A;  3ETR B;  4PVJ A;  3W8W A;  3JS8 A;  3AMZ A;  2MBR A;  3POP A;  2W54 A;  2IPI A;  4BC9 A;  1FFU C;  3NVY B;  2W55 A;  5D79 A;  4JB1 A;  5L6F A;  4PZF A;  1E0Y A;  4BC7 A;  1MBT A;  1T3Q C;  2PLS A;  1UXY A;  2W3R A;  3C0P A;  5FXD A;  1W1R A;  2P3H A;  3RJA A;  1WVF A;  1VDV A;  2P4P A;  5I1V A;  1N60 C;  3SR6 B;  2PLI A;  2Y08 A;  4XLO A;  3S1F A;  5AE2 A;  4ML8 A;  3BW7 A;  3S1C A;  4EC3 A;  1JRP A;  3LLB A;  1N62 C;  3LAE A;  1FIQ B;  1RM6 B;  2W3S A;  2VFR A;  3I99 A;  2Y3R A;  5HQX A;  5G5G B;  4PVK A;  1N5X A;  3W8X A;  1QLT A;  2VFV A;  2NQW A;  4DNS A;  4HG0 A;  1VAO A;  1F0X A;  3RJ8 A;  2AXR A;  1N63 C;  2BVF A;  1DIQ A;  3FW9 A;  1V97 A;  2RK5 A;  2BVG A;  5FXF A;  3VTE A;  3FWA A;  3KJM A;  3PM9 A;  2R2Z A;  2Y4G A;  5FXE A;  1W1M A;  2GQT A;  1JRO A;  5AE3 A;  2WDW A;  2VAO A;  3GSY A;  5I1W A;  1WVE A;  2GQU A;  1AHZ A;  1AHV A;  4PWB A;  3S1E A;  1DII A;  4OAL A;  3HRD C;  4ZOH B;  3D2J A;  2E3T A;  1W1Q A;  4MLA A;  3S1D A;  3NVZ B;  1N61 C;  4JAY A;  1FO4 A;  3NVW B;  5L6G A;  3TSJ A;  5ADZ A;  1W1J A;  3W8Z A;  3HSU A;  4PWC A;  1W1L A;  5AE1 A;  3FW8 A;  4UD8 A;  2EXR A;  3PQB A;  5G5H B;  2VFU A;  1W1O A;  2R8D A;  1HSK A;  2Y3S A;  1SB3 B;  3NRZ B;  2UUU A;  2O3G A;  1QLU A;  3DED A;  2Q85 A;  1FFV C;  2VFS A;  3D2H A;  4O95 A;  1ZXI C;  2VFT A;  1ZR6 A;  4PVE A;  3B9J B;  2P13 A;  1N5W C;  2QKN A;  3EUB 3;  1AHU A;  5HMR A;  3D2D A;  3DQ0 A;  1W1K A;  4PYT A;  5K8E A;  1E8H A;  3TSH A;  3AN1 A;  2BVH A;  1W1S A;  3NS1 B;  5HHZ A;  3NVV B;  1I19 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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