4XLOA

Crystal structure of encm (crystallized with 4 mm nadph)
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
458
structure length
458
Chain Sequence
QLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARCTSTPDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIKVSRRLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFGWLSRKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVVTAFEFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLRLAPPLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKATLPYRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPFTQLELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWAREGYRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTNLFRLNQNIPPS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
pubmed doi rcsb
source organism Streptomyces maritimus
molecule tags Oxidoreductase
molecule keywords FAD-dependent oxygenase EncM
total genus 141
structure length 458
sequence length 458
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2015-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4xloA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4xloA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 4xloA03
2Y3SA 3B9JB 4BBYA 5FXEA 3FWAA 1W1RA 4PYTA 3HSUA 5K8EA 2P4PA 3S1EA 2W3SA 2VFVA 1AHUA 1T3QC 5HHZA 1W1MA 2VFTA 1HSKA 1WVFA 3D2DA 3S1FA 4JB1A 4PVJA 2VAOA 1MBTA 2IPIA 1N60C 2O3GA 2PLSA 4PWBA 1FFUC 2R2ZA 3TX1A 1ZXIC 1QLTA 1JRPA 3DQ0A 2R8DA 2Y3RA 2I0KA 3PQBA 1ZR6A 1N62C 5G5GB 3RJ8A 1N5WC 2BVFA 3FW9A 3NVYB 4PVKA 1N63C 5L6FA 3NVWB 1UXYA 1W1KA 1RM6B 1F0XA 2NQWA 1W1QA 4HG0A 1W1JA 2EXRA 2VFSA 1DIQA 3I99A 1FFVC 1JROA 4O95A 4OALA 5ADZA 1WVEA 3D2HA 2YVSA 1DIIA 4PZFA 1SB3B 3FW8A 3LAEA 3AM9A 1N61C 1MBBA 4EC3A 3TSHA 1VDVA 2QPMA 3JS8A 3C0PA 4PWCA 2W55A 3PM9A 5AE2A 2Q4WA 3VTEA 3RJAA 1QLUA 4PVEA 1I19A 1FO4A 1AHVA 1W1LA 3HRDC 3W8ZA 5FXPA 3AN1A 4XLOA 3TSJA 5AWVA 1FIQB 5HMRA 2QKNA 4ZOHB 3KJMA 1WYGA 2RK5A 4BCAA 3POPA 5I1WA 3FW7A 4BC9A 5G5HB 5AE3A 3NS1B 3EUB3 2WDWA 2Q85A 3NRZB 2GQUA 3NVZB 2PLIA 3S1DA 2BVHA 4UD8A 4JAYA 5L6GA 1E8HA 2W3RA 4PVHA 3S1CA 2VFUA 1W1OA 2AXRA 3SR6B 2P3HA 3GSYA 3AMZA 2E3TA 4MLAA 3BW7A 5D79A 2Y08A 3NVVB 1W1SA 5FXDA 1N5XA 4DNSA 2GQTA 2Y4GA 3D2JA 2VFRA 2BVGA 1DZNA 2MBRA 5FXFA 2OAIA 3DEDA 3LLBA 4ML8A 3W8XA 1V97A 3ETRB 1AHZA 5I1VA 2P13A 5HQXA 3W8WA 1E0YA 2W54A 4BC7A 5AE1A 1VAOA 1E8FA 1E8GA
chains in the Genus database with same CATH superfamily
2Y3SA 3B9JB 4BBYA 5FXEA 3FWAA 1W1RA 4PYTA 3HSUA 5K8EA 2P4PA 3S1EA 2W3SA 2VFVA 1AHUA 1T3QC 5HHZA 1W1MA 2VFTA 1HSKA 1WVFA 3D2DA 3S1FA 4JB1A 4PVJA 2VAOA 1MBTA 2IPIA 1N60C 2O3GA 2PLSA 4PWBA 1FFUC 2R2ZA 3TX1A 1ZXIC 1QLTA 1JRPA 3DQ0A 2R8DA 2Y3RA 2I0KA 3PQBA 1ZR6A 1N62C 5G5GB 3RJ8A 1N5WC 2BVFA 3FW9A 3NVYB 4PVKA 1N63C 5L6FA 3NVWB 1UXYA 1W1KA 1RM6B 1F0XA 2NQWA 2UUVA 1W1QA 4HG0A 1W1JA 2EXRA 2VFSA 1DIQA 3I99A 1FFVC 1JROA 4O95A 4OALA 5ADZA 1WVEA 3D2HA 2YVSA 1DIIA 4PZFA 1SB3B 3FW8A 3LAEA 3AM9A 1N61C 1MBBA 4EC3A 3TSHA 1VDVA 2QPMA 3JS8A 3C0PA 4PWCA 2W55A 3EJEB 3EJDB 3PM9A 5AE2A 2Q4WA 3VTEA 3RJAA 1QLUA 4PVEA 1I19A 1FO4A 1AHVA 1W1LA 3HRDC 3EJBB 3W8ZA 5FXPA 3AN1A 4XLOA 3TSJA 5AWVA 1FIQB 5HMRA 2QKNA 4ZOHB 3KJMA 1WYGA 2RK5A 4BCAA 3POPA 5I1WA 3FW7A 4BC9A 5G5HB 5AE3A 3NS1B 3EUB3 2WDWA 2Q85A 3NRZB 2GQUA 3NVZB 2PLIA 3S1DA 2BVHA 4UD8A 4JAYA 5L6GA 1E8HA 2W3RA 4PVHA 3S1CA 2VFUA 1W1OA 2AXRA 3SR6B 2P3HA 3GSYA 3AMZA 2E3TA 4MLAA 3BW7A 5D79A 2Y08A 3NVVB 1W1SA 5FXDA 1N5XA 4DNSA 2GQTA 2Y4GA 3D2JA 2VFRA 2BVGA 1DZNA 2MBRA 5FXFA 2OAIA 3DEDA 3LLBA 4ML8A 3W8XA 1V97A 2UUUA 3ETRB 1AHZA 5I1VA 2P13A 5HQXA 3W8WA 1E0YA 2W54A 4BC7A 5AE1A 1VAOA 1E8FA 1E8GA
chains in the Genus database with same CATH topology
2Y3SA 3B9JB 4BBYA 5FXEA 3FWAA 1W1RA 4PYTA 3HSUA 5K8EA 2P4PA 3S1EA 2W3SA 2VFVA 1AHUA 1T3QC 5HHZA 1W1MA 2VFTA 1HSKA 1WVFA 3D2DA 3S1FA 4JB1A 4PVJA 2VAOA 1MBTA 2IPIA 1N60C 2O3GA 2PLSA 4PWBA 1FFUC 2R2ZA 3TX1A 1ZXIC 1QLTA 1JRPA 3DQ0A 2R8DA 2Y3RA 2I0KA 3PQBA 1ZR6A 1N62C 5G5GB 3RJ8A 1N5WC 2BVFA 3FW9A 3NVYB 4PVKA 1N63C 5L6FA 3NVWB 1UXYA 1W1KA 1RM6B 1F0XA 2NQWA 2UUVA 1W1QA 4HG0A 1W1JA 2EXRA 2VFSA 1DIQA 3I99A 1FFVC 1JROA 4O95A 4OALA 5ADZA 1WVEA 3D2HA 2YVSA 1DIIA 4PZFA 1SB3B 3FW8A 3LAEA 3AM9A 1N61C 1MBBA 4EC3A 3TSHA 1VDVA 2QPMA 3JS8A 3C0PA 4PWCA 2W55A 3PM9A 5AE2A 2Q4WA 3VTEA 3RJAA 1QLUA 4PVEA 1I19A 1FO4A 1AHVA 1W1LA 3HRDC 3W8ZA 5FXPA 3AN1A 4XLOA 3TSJA 5AWVA 1FIQB 5HMRA 2QKNA 4ZOHB 3KJMA 1WYGA 2RK5A 4BCAA 3POPA 5I1WA 3FW7A 4BC9A 5G5HB 5AE3A 3NS1B 3EUB3 2WDWA 2Q85A 3NRZB 2GQUA 3NVZB 2PLIA 3S1DA 2BVHA 4UD8A 4JAYA 5L6GA 1E8HA 2W3RA 4PVHA 3S1CA 2VFUA 1W1OA 2AXRA 3SR6B 2P3HA 3GSYA 3AMZA 2E3TA 4MLAA 3BW7A 5D79A 2Y08A 3NVVB 1W1SA 5FXDA 1N5XA 4DNSA 2GQTA 2Y4GA 3D2JA 2VFRA 2BVGA 1DZNA 2MBRA 5FXFA 2OAIA 3DEDA 3LLBA 4ML8A 3W8XA 1V97A 2UUUA 3ETRB 1AHZA 5I1VA 2P13A 5HQXA 3W8WA 1E0YA 2W54A 4BC7A 5AE1A 1VAOA 1E8FA 1E8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y3S A;  3B9J B;  4BBY A;  5FXE A;  3FWA A;  1W1R A;  4PYT A;  3HSU A;  5K8E A;  2P4P A;  3S1E A;  2W3S A;  2VFV A;  1AHU A;  1T3Q C;  5HHZ A;  1W1M A;  2VFT A;  1HSK A;  1WVF A;  3D2D A;  3S1F A;  4JB1 A;  4PVJ A;  2VAO A;  1MBT A;  2IPI A;  1N60 C;  2O3G A;  2PLS A;  4PWB A;  1FFU C;  2R2Z A;  3TX1 A;  1ZXI C;  1QLT A;  1JRP A;  3DQ0 A;  2R8D A;  2Y3R A;  2I0K A;  3PQB A;  1ZR6 A;  1N62 C;  5G5G B;  3RJ8 A;  1N5W C;  2BVF A;  3FW9 A;  3NVY B;  4PVK A;  1N63 C;  5L6F A;  3NVW B;  1UXY A;  1W1K A;  1RM6 B;  1F0X A;  2NQW A;  1W1Q A;  4HG0 A;  1W1J A;  2EXR A;  2VFS A;  1DIQ A;  3I99 A;  1FFV C;  1JRO A;  4O95 A;  4OAL A;  5ADZ A;  1WVE A;  3D2H A;  2YVS A;  1DII A;  4PZF A;  1SB3 B;  3FW8 A;  3LAE A;  3AM9 A;  1N61 C;  1MBB A;  4EC3 A;  3TSH A;  1VDV A;  2QPM A;  3JS8 A;  3C0P A;  4PWC A;  2W55 A;  3PM9 A;  5AE2 A;  2Q4W A;  3VTE A;  3RJA A;  1QLU A;  4PVE A;  1I19 A;  1FO4 A;  1AHV A;  1W1L A;  3HRD C;  3W8Z A;  5FXP A;  3AN1 A;  4XLO A;  3TSJ A;  5AWV A;  1FIQ B;  5HMR A;  2QKN A;  4ZOH B;  3KJM A;  1WYG A;  2RK5 A;  4BCA A;  3POP A;  5I1W A;  3FW7 A;  4BC9 A;  5G5H B;  5AE3 A;  3NS1 B;  3EUB 3;  2WDW A;  2Q85 A;  3NRZ B;  2GQU A;  3NVZ B;  2PLI A;  3S1D A;  2BVH A;  4UD8 A;  4JAY A;  5L6G A;  1E8H A;  2W3R A;  4PVH A;  3S1C A;  2VFU A;  1W1O A;  2AXR A;  3SR6 B;  2P3H A;  3GSY A;  3AMZ A;  2E3T A;  4MLA A;  3BW7 A;  5D79 A;  2Y08 A;  3NVV B;  1W1S A;  5FXD A;  1N5X A;  4DNS A;  2GQT A;  2Y4G A;  3D2J A;  2VFR A;  2BVG A;  1DZN A;  2MBR A;  5FXF A;  2OAI A;  3DED A;  3LLB A;  4ML8 A;  3W8X A;  1V97 A;  3ETR B;  1AHZ A;  5I1V A;  2P13 A;  5HQX A;  3W8W A;  1E0Y A;  2W54 A;  4BC7 A;  5AE1 A;  1VAO A;  1E8F A;  1E8G A; 
#chains in the Genus database with same CATH topology
 2Y3S A;  3B9J B;  4BBY A;  5FXE A;  3FWA A;  1W1R A;  4PYT A;  3HSU A;  5K8E A;  2P4P A;  3S1E A;  2W3S A;  2VFV A;  1AHU A;  1T3Q C;  5HHZ A;  1W1M A;  2VFT A;  1HSK A;  1WVF A;  3D2D A;  3S1F A;  4JB1 A;  4PVJ A;  2VAO A;  1MBT A;  2IPI A;  1N60 C;  2O3G A;  2PLS A;  4PWB A;  1FFU C;  2R2Z A;  3TX1 A;  1ZXI C;  1QLT A;  1JRP A;  3DQ0 A;  2R8D A;  2Y3R A;  2I0K A;  3PQB A;  1ZR6 A;  1N62 C;  5G5G B;  3RJ8 A;  1N5W C;  2BVF A;  3FW9 A;  3NVY B;  4PVK A;  1N63 C;  5L6F A;  3NVW B;  1UXY A;  1W1K A;  1RM6 B;  1F0X A;  2NQW A;  2UUV A;  1W1Q A;  4HG0 A;  1W1J A;  2EXR A;  2VFS A;  1DIQ A;  3I99 A;  1FFV C;  1JRO A;  4O95 A;  4OAL A;  5ADZ A;  1WVE A;  3D2H A;  2YVS A;  1DII A;  4PZF A;  1SB3 B;  3FW8 A;  3LAE A;  3AM9 A;  1N61 C;  1MBB A;  4EC3 A;  3TSH A;  1VDV A;  2QPM A;  3JS8 A;  3C0P A;  4PWC A;  2W55 A;  3EJE B;  3EJD B;  3PM9 A;  5AE2 A;  2Q4W A;  3VTE A;  3RJA A;  1QLU A;  4PVE A;  1I19 A;  1FO4 A;  1AHV A;  1W1L A;  3HRD C;  3EJB B;  3W8Z A;  5FXP A;  3AN1 A;  4XLO A;  3TSJ A;  5AWV A;  1FIQ B;  5HMR A;  2QKN A;  4ZOH B;  3KJM A;  1WYG A;  2RK5 A;  4BCA A;  3POP A;  5I1W A;  3FW7 A;  4BC9 A;  5G5H B;  5AE3 A;  3NS1 B;  3EUB 3;  2WDW A;  2Q85 A;  3NRZ B;  2GQU A;  3NVZ B;  2PLI A;  3S1D A;  2BVH A;  4UD8 A;  4JAY A;  5L6G A;  1E8H A;  2W3R A;  4PVH A;  3S1C A;  2VFU A;  1W1O A;  2AXR A;  3SR6 B;  2P3H A;  3GSY A;  3AMZ A;  2E3T A;  4MLA A;  3BW7 A;  5D79 A;  2Y08 A;  3NVV B;  1W1S A;  5FXD A;  1N5X A;  4DNS A;  2GQT A;  2Y4G A;  3D2J A;  2VFR A;  2BVG A;  1DZN A;  2MBR A;  5FXF A;  2OAI A;  3DED A;  3LLB A;  4ML8 A;  3W8X A;  1V97 A;  2UUU A;  3ETR B;  1AHZ A;  5I1V A;  2P13 A;  5HQX A;  3W8W A;  1E0Y A;  2W54 A;  4BC7 A;  5AE1 A;  1VAO A;  1E8F A;  1E8G A; 
#chains in the Genus database with same CATH homology
 2Y3S A;  3B9J B;  4BBY A;  5FXE A;  3FWA A;  1W1R A;  4PYT A;  3HSU A;  5K8E A;  2P4P A;  3S1E A;  2W3S A;  2VFV A;  1AHU A;  1T3Q C;  5HHZ A;  1W1M A;  2VFT A;  1HSK A;  1WVF A;  3D2D A;  3S1F A;  4JB1 A;  4PVJ A;  2VAO A;  1MBT A;  2IPI A;  1N60 C;  2O3G A;  2PLS A;  4PWB A;  1FFU C;  2R2Z A;  3TX1 A;  1ZXI C;  1QLT A;  1JRP A;  3DQ0 A;  2R8D A;  2Y3R A;  2I0K A;  3PQB A;  1ZR6 A;  1N62 C;  5G5G B;  3RJ8 A;  1N5W C;  2BVF A;  3FW9 A;  3NVY B;  4PVK A;  1N63 C;  5L6F A;  3NVW B;  1UXY A;  1W1K A;  1RM6 B;  1F0X A;  2NQW A;  2UUV A;  1W1Q A;  4HG0 A;  1W1J A;  2EXR A;  2VFS A;  1DIQ A;  3I99 A;  1FFV C;  1JRO A;  4O95 A;  4OAL A;  5ADZ A;  1WVE A;  3D2H A;  2YVS A;  1DII A;  4PZF A;  1SB3 B;  3FW8 A;  3LAE A;  3AM9 A;  1N61 C;  1MBB A;  4EC3 A;  3TSH A;  1VDV A;  2QPM A;  3JS8 A;  3C0P A;  4PWC A;  2W55 A;  3PM9 A;  5AE2 A;  2Q4W A;  3VTE A;  3RJA A;  1QLU A;  4PVE A;  1I19 A;  1FO4 A;  1AHV A;  1W1L A;  3HRD C;  3W8Z A;  5FXP A;  3AN1 A;  4XLO A;  3TSJ A;  5AWV A;  1FIQ B;  5HMR A;  2QKN A;  4ZOH B;  3KJM A;  1WYG A;  2RK5 A;  4BCA A;  3POP A;  5I1W A;  3FW7 A;  4BC9 A;  5G5H B;  5AE3 A;  3NS1 B;  3EUB 3;  2WDW A;  2Q85 A;  3NRZ B;  2GQU A;  3NVZ B;  2PLI A;  3S1D A;  2BVH A;  4UD8 A;  4JAY A;  5L6G A;  1E8H A;  2W3R A;  4PVH A;  3S1C A;  2VFU A;  1W1O A;  2AXR A;  3SR6 B;  2P3H A;  3GSY A;  3AMZ A;  2E3T A;  4MLA A;  3BW7 A;  5D79 A;  2Y08 A;  3NVV B;  1W1S A;  5FXD A;  1N5X A;  4DNS A;  2GQT A;  2Y4G A;  3D2J A;  2VFR A;  2BVG A;  1DZN A;  2MBR A;  5FXF A;  2OAI A;  3DED A;  3LLB A;  4ML8 A;  3W8X A;  1V97 A;  2UUU A;  3ETR B;  1AHZ A;  5I1V A;  2P13 A;  5HQX A;  3W8W A;  1E0Y A;  2W54 A;  4BC7 A;  5AE1 A;  1VAO A;  1E8F A;  1E8G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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