4XLOA

Crystal structure of encm (crystallized with 4 mm nadph)
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
458
structure length
458
Chain Sequence
QLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARCTSTPDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIKVSRRLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFGWLSRKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVVTAFEFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLRLAPPLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKATLPYRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPFTQLELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWAREGYRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTNLFRLNQNIPPS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Oxidoreductase
molecule keywords FAD-dependent oxygenase EncM
publication title Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
pubmed doi rcsb
source organism Streptomyces maritimus
total genus 141
structure length 458
sequence length 458
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2015-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4xloA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4xloA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 4xloA03
4OALA 2Y4GA 3W8XA 2QKNA 2W54A 4PYTA 1VDVA 3S1FA 3DEDA 5HHZA 1E8FA 2W55A 2R2ZA 4BBYA 3S1DA 2Y3SA 2Q4WA 2P4PA 3JS8A 3NVZB 4UD8A 3LAEA 1DIIA 1N63C 3SR6B 1JRPA 3HRDC 2PLIA 2BVHA 1V97A 3FW8A 3W8WA 1E8GA 3W8ZA 5HQXA 1WVFA 2MBRA 1RM6B 1QLUA 1F0XA 1W1RA 3ETRB 3D2JA 4PVJA 3B9JB 5AE1A 5G5GB 2AXRA 2OAIA 1T3QC 2VFUA 4DNSA 1FFUC 5D79A 2GQUA 2BVFA 3LLBA 2VFVA 1W1OA 3S1CA 3AMZA 5FXPA 1WVEA 1N62C 2VFRA 3BW7A 4JAYA 1I19A 5AE3A 1W1LA 4PWCA 3DQ0A 2P3HA 4O95A 3HSUA 1FFVC 4ZOHB 3FW9A 1W1MA 1N61C 1JROA 2NQWA 1E8HA 1W1KA 2VFSA 5ADZA 2R8DA 3NVYB 3RJAA 3NRZB 1W1JA 1AHUA 4PVEA 5K8EA 1AHZA 4XLOA 2W3RA 3NVVB 1FIQB 5AE2A 1W1QA 2E3TA 5FXFA 1VAOA 1W1SA 1DIQA 1AHVA 4ML8A 3D2DA 4BC7A 5I1WA 4PWBA 3NVWB 3AN1A 4PVKA 1WYGA 3TX1A 3PM9A 3POPA 2EXRA 5FXEA 2WDWA 2BVGA 1ZR6A 3TSHA 5HMRA 4EC3A 1N5WC 1E0YA 1N5XA 2RK5A 4BCAA 1MBBA 5L6FA 3KJMA 3S1EA 1FO4A 1QLTA 3AM9A 5FXDA 4PVHA 2O3GA 3RJ8A 3D2HA 4JB1A 1UXYA 1MBTA 2Y08A 2Q85A 2VAOA 2GQTA 2VFTA 3I99A 5L6GA 1SB3B 3GSYA 3C0PA 4HG0A 4MLAA 1HSKA 4BC9A 4PZFA 1ZXIC 5I1VA 2W3SA 1N60C 2IPIA 2I0KA 5AWVA 3FWAA 2PLSA 3EUB3 3VTEA 2Y3RA 3PQBA 5G5HB 3NS1B 2QPMA 3TSJA 1DZNA 3FW7A 2P13A 2YVSA
chains in the Genus database with same CATH superfamily
4OALA 2Y4GA 3W8XA 2QKNA 2W54A 4PYTA 1VDVA 3S1FA 3DEDA 5HHZA 1E8FA 2W55A 2R2ZA 4BBYA 3S1DA 2Y3SA 2Q4WA 2P4PA 3JS8A 3NVZB 4UD8A 3LAEA 1DIIA 1N63C 3SR6B 1JRPA 3HRDC 2PLIA 2BVHA 1V97A 3FW8A 3W8WA 1E8GA 3W8ZA 5HQXA 1WVFA 2MBRA 1RM6B 1QLUA 1F0XA 1W1RA 3ETRB 3D2JA 3EJBB 4PVJA 3B9JB 5AE1A 5G5GB 2AXRA 2OAIA 1T3QC 2VFUA 2UUVA 4DNSA 1FFUC 5D79A 2GQUA 2BVFA 3LLBA 2VFVA 3EJDB 1W1OA 3S1CA 3AMZA 5FXPA 1WVEA 1N62C 2VFRA 3BW7A 4JAYA 1I19A 5AE3A 1W1LA 4PWCA 3DQ0A 2P3HA 4O95A 3HSUA 1FFVC 4ZOHB 3FW9A 3EJEB 1W1MA 1N61C 1JROA 2NQWA 1E8HA 1W1KA 2VFSA 3NVYB 5ADZA 2R8DA 3RJAA 3NRZB 1W1JA 1AHUA 4PVEA 5K8EA 1AHZA 4XLOA 2W3RA 3NVVB 1FIQB 5AE2A 1W1QA 2E3TA 5FXFA 1VAOA 1W1SA 1DIQA 1AHVA 4ML8A 3D2DA 4BC7A 5I1WA 4PWBA 3NVWB 3AN1A 4PVKA 1WYGA 3TX1A 3PM9A 3POPA 2EXRA 5FXEA 2WDWA 2BVGA 1ZR6A 3TSHA 5HMRA 4EC3A 1N5WC 1E0YA 1N5XA 2RK5A 4BCAA 1MBBA 5L6FA 3KJMA 3S1EA 1FO4A 1QLTA 3AM9A 5FXDA 4PVHA 2O3GA 3RJ8A 3D2HA 4JB1A 1UXYA 1MBTA 2Y08A 2Q85A 2VAOA 2GQTA 2VFTA 3I99A 5L6GA 1SB3B 3GSYA 3C0PA 4HG0A 4MLAA 1HSKA 4BC9A 4PZFA 1ZXIC 5I1VA 2W3SA 1N60C 2IPIA 2I0KA 5AWVA 3FWAA 2PLSA 3EUB3 3VTEA 2Y3RA 3PQBA 5G5HB 3NS1B 2QPMA 3TSJA 1DZNA 3FW7A 2UUUA 2P13A 2YVSA
chains in the Genus database with same CATH topology
4OALA 2Y4GA 3W8XA 2QKNA 2W54A 4PYTA 1VDVA 3S1FA 3DEDA 5HHZA 1E8FA 2W55A 2R2ZA 4BBYA 3S1DA 2Y3SA 2Q4WA 2P4PA 3JS8A 3NVZB 4UD8A 3LAEA 1DIIA 1N63C 3SR6B 1JRPA 3HRDC 2PLIA 2BVHA 1V97A 3FW8A 3W8WA 1E8GA 3W8ZA 5HQXA 1WVFA 2MBRA 1RM6B 1QLUA 1F0XA 1W1RA 3ETRB 3D2JA 4PVJA 3B9JB 5AE1A 5G5GB 2AXRA 2OAIA 1T3QC 2VFUA 2UUVA 4DNSA 1FFUC 5D79A 2GQUA 2BVFA 3LLBA 2VFVA 1W1OA 3S1CA 3AMZA 5FXPA 1WVEA 1N62C 2VFRA 3BW7A 4JAYA 1I19A 5AE3A 1W1LA 4PWCA 3DQ0A 2P3HA 4O95A 3HSUA 1FFVC 4ZOHB 3FW9A 1W1MA 1N61C 1JROA 2NQWA 1E8HA 1W1KA 2VFSA 5ADZA 2R8DA 3NVYB 3RJAA 3NRZB 1W1JA 1AHUA 4PVEA 5K8EA 1AHZA 4XLOA 2W3RA 3NVVB 1FIQB 5AE2A 1W1QA 2E3TA 5FXFA 1VAOA 1W1SA 1DIQA 1AHVA 4ML8A 3D2DA 4BC7A 5I1WA 4PWBA 3NVWB 3AN1A 4PVKA 1WYGA 3TX1A 3PM9A 3POPA 2EXRA 5FXEA 2WDWA 2BVGA 1ZR6A 3TSHA 5HMRA 4EC3A 1N5WC 1E0YA 1N5XA 2RK5A 4BCAA 1MBBA 5L6FA 3KJMA 3S1EA 1FO4A 1QLTA 3AM9A 5FXDA 4PVHA 2O3GA 3RJ8A 3D2HA 4JB1A 1UXYA 1MBTA 2Y08A 2Q85A 2VAOA 2GQTA 2VFTA 3I99A 5L6GA 1SB3B 3GSYA 3C0PA 4HG0A 4MLAA 1HSKA 4BC9A 4PZFA 1ZXIC 5I1VA 2W3SA 1N60C 2IPIA 2I0KA 5AWVA 3FWAA 2PLSA 3EUB3 3VTEA 2Y3RA 3PQBA 5G5HB 3NS1B 2QPMA 3TSJA 1DZNA 3FW7A 2UUUA 2P13A 2YVSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OAL A;  2Y4G A;  3W8X A;  2QKN A;  2W54 A;  4PYT A;  1VDV A;  3S1F A;  3DED A;  5HHZ A;  1E8F A;  2W55 A;  2R2Z A;  4BBY A;  3S1D A;  2Y3S A;  2Q4W A;  2P4P A;  3JS8 A;  3NVZ B;  4UD8 A;  3LAE A;  1DII A;  1N63 C;  3SR6 B;  1JRP A;  3HRD C;  2PLI A;  2BVH A;  1V97 A;  3FW8 A;  3W8W A;  1E8G A;  3W8Z A;  5HQX A;  1WVF A;  2MBR A;  1RM6 B;  1QLU A;  1F0X A;  1W1R A;  3ETR B;  3D2J A;  4PVJ A;  3B9J B;  5AE1 A;  5G5G B;  2AXR A;  2OAI A;  1T3Q C;  2VFU A;  4DNS A;  1FFU C;  5D79 A;  2GQU A;  2BVF A;  3LLB A;  2VFV A;  1W1O A;  3S1C A;  3AMZ A;  5FXP A;  1WVE A;  1N62 C;  2VFR A;  3BW7 A;  4JAY A;  1I19 A;  5AE3 A;  1W1L A;  4PWC A;  3DQ0 A;  2P3H A;  4O95 A;  3HSU A;  1FFV C;  4ZOH B;  3FW9 A;  1W1M A;  1N61 C;  1JRO A;  2NQW A;  1E8H A;  1W1K A;  2VFS A;  5ADZ A;  2R8D A;  3NVY B;  3RJA A;  3NRZ B;  1W1J A;  1AHU A;  4PVE A;  5K8E A;  1AHZ A;  4XLO A;  2W3R A;  3NVV B;  1FIQ B;  5AE2 A;  1W1Q A;  2E3T A;  5FXF A;  1VAO A;  1W1S A;  1DIQ A;  1AHV A;  4ML8 A;  3D2D A;  4BC7 A;  5I1W A;  4PWB A;  3NVW B;  3AN1 A;  4PVK A;  1WYG A;  3TX1 A;  3PM9 A;  3POP A;  2EXR A;  5FXE A;  2WDW A;  2BVG A;  1ZR6 A;  3TSH A;  5HMR A;  4EC3 A;  1N5W C;  1E0Y A;  1N5X A;  2RK5 A;  4BCA A;  1MBB A;  5L6F A;  3KJM A;  3S1E A;  1FO4 A;  1QLT A;  3AM9 A;  5FXD A;  4PVH A;  2O3G A;  3RJ8 A;  3D2H A;  4JB1 A;  1UXY A;  1MBT A;  2Y08 A;  2Q85 A;  2VAO A;  2GQT A;  2VFT A;  3I99 A;  5L6G A;  1SB3 B;  3GSY A;  3C0P A;  4HG0 A;  4MLA A;  1HSK A;  4BC9 A;  4PZF A;  1ZXI C;  5I1V A;  2W3S A;  1N60 C;  2IPI A;  2I0K A;  5AWV A;  3FWA A;  2PLS A;  3EUB 3;  3VTE A;  2Y3R A;  3PQB A;  5G5H B;  3NS1 B;  2QPM A;  3TSJ A;  1DZN A;  3FW7 A;  2P13 A;  2YVS A; 
#chains in the Genus database with same CATH topology
 4OAL A;  2Y4G A;  3W8X A;  2QKN A;  2W54 A;  4PYT A;  1VDV A;  3S1F A;  3DED A;  5HHZ A;  1E8F A;  2W55 A;  2R2Z A;  4BBY A;  3S1D A;  2Y3S A;  2Q4W A;  2P4P A;  3JS8 A;  3NVZ B;  4UD8 A;  3LAE A;  1DII A;  1N63 C;  3SR6 B;  1JRP A;  3HRD C;  2PLI A;  2BVH A;  1V97 A;  3FW8 A;  3W8W A;  1E8G A;  3W8Z A;  5HQX A;  1WVF A;  2MBR A;  1RM6 B;  1QLU A;  1F0X A;  1W1R A;  3ETR B;  3D2J A;  3EJB B;  4PVJ A;  3B9J B;  5AE1 A;  5G5G B;  2AXR A;  2OAI A;  1T3Q C;  2VFU A;  2UUV A;  4DNS A;  1FFU C;  5D79 A;  2GQU A;  2BVF A;  3LLB A;  2VFV A;  3EJD B;  1W1O A;  3S1C A;  3AMZ A;  5FXP A;  1WVE A;  1N62 C;  2VFR A;  3BW7 A;  4JAY A;  1I19 A;  5AE3 A;  1W1L A;  4PWC A;  3DQ0 A;  2P3H A;  4O95 A;  3HSU A;  1FFV C;  4ZOH B;  3FW9 A;  3EJE B;  1W1M A;  1N61 C;  1JRO A;  2NQW A;  1E8H A;  1W1K A;  2VFS A;  3NVY B;  5ADZ A;  2R8D A;  3RJA A;  3NRZ B;  1W1J A;  1AHU A;  4PVE A;  5K8E A;  1AHZ A;  4XLO A;  2W3R A;  3NVV B;  1FIQ B;  5AE2 A;  1W1Q A;  2E3T A;  5FXF A;  1VAO A;  1W1S A;  1DIQ A;  1AHV A;  4ML8 A;  3D2D A;  4BC7 A;  5I1W A;  4PWB A;  3NVW B;  3AN1 A;  4PVK A;  1WYG A;  3TX1 A;  3PM9 A;  3POP A;  2EXR A;  5FXE A;  2WDW A;  2BVG A;  1ZR6 A;  3TSH A;  5HMR A;  4EC3 A;  1N5W C;  1E0Y A;  1N5X A;  2RK5 A;  4BCA A;  1MBB A;  5L6F A;  3KJM A;  3S1E A;  1FO4 A;  1QLT A;  3AM9 A;  5FXD A;  4PVH A;  2O3G A;  3RJ8 A;  3D2H A;  4JB1 A;  1UXY A;  1MBT A;  2Y08 A;  2Q85 A;  2VAO A;  2GQT A;  2VFT A;  3I99 A;  5L6G A;  1SB3 B;  3GSY A;  3C0P A;  4HG0 A;  4MLA A;  1HSK A;  4BC9 A;  4PZF A;  1ZXI C;  5I1V A;  2W3S A;  1N60 C;  2IPI A;  2I0K A;  5AWV A;  3FWA A;  2PLS A;  3EUB 3;  3VTE A;  2Y3R A;  3PQB A;  5G5H B;  3NS1 B;  2QPM A;  3TSJ A;  1DZN A;  3FW7 A;  2UUU A;  2P13 A;  2YVS A; 
#chains in the Genus database with same CATH homology
 4OAL A;  2Y4G A;  3W8X A;  2QKN A;  2W54 A;  4PYT A;  1VDV A;  3S1F A;  3DED A;  5HHZ A;  1E8F A;  2W55 A;  2R2Z A;  4BBY A;  3S1D A;  2Y3S A;  2Q4W A;  2P4P A;  3JS8 A;  3NVZ B;  4UD8 A;  3LAE A;  1DII A;  1N63 C;  3SR6 B;  1JRP A;  3HRD C;  2PLI A;  2BVH A;  1V97 A;  3FW8 A;  3W8W A;  1E8G A;  3W8Z A;  5HQX A;  1WVF A;  2MBR A;  1RM6 B;  1QLU A;  1F0X A;  1W1R A;  3ETR B;  3D2J A;  4PVJ A;  3B9J B;  5AE1 A;  5G5G B;  2AXR A;  2OAI A;  1T3Q C;  2VFU A;  2UUV A;  4DNS A;  1FFU C;  5D79 A;  2GQU A;  2BVF A;  3LLB A;  2VFV A;  1W1O A;  3S1C A;  3AMZ A;  5FXP A;  1WVE A;  1N62 C;  2VFR A;  3BW7 A;  4JAY A;  1I19 A;  5AE3 A;  1W1L A;  4PWC A;  3DQ0 A;  2P3H A;  4O95 A;  3HSU A;  1FFV C;  4ZOH B;  3FW9 A;  1W1M A;  1N61 C;  1JRO A;  2NQW A;  1E8H A;  1W1K A;  2VFS A;  5ADZ A;  2R8D A;  3NVY B;  3RJA A;  3NRZ B;  1W1J A;  1AHU A;  4PVE A;  5K8E A;  1AHZ A;  4XLO A;  2W3R A;  3NVV B;  1FIQ B;  5AE2 A;  1W1Q A;  2E3T A;  5FXF A;  1VAO A;  1W1S A;  1DIQ A;  1AHV A;  4ML8 A;  3D2D A;  4BC7 A;  5I1W A;  4PWB A;  3NVW B;  3AN1 A;  4PVK A;  1WYG A;  3TX1 A;  3PM9 A;  3POP A;  2EXR A;  5FXE A;  2WDW A;  2BVG A;  1ZR6 A;  3TSH A;  5HMR A;  4EC3 A;  1N5W C;  1E0Y A;  1N5X A;  2RK5 A;  4BCA A;  1MBB A;  5L6F A;  3KJM A;  3S1E A;  1FO4 A;  1QLT A;  3AM9 A;  5FXD A;  4PVH A;  2O3G A;  3RJ8 A;  3D2H A;  4JB1 A;  1UXY A;  1MBT A;  2Y08 A;  2Q85 A;  2VAO A;  2GQT A;  2VFT A;  3I99 A;  5L6G A;  1SB3 B;  3GSY A;  3C0P A;  4HG0 A;  4MLA A;  1HSK A;  4BC9 A;  4PZF A;  1ZXI C;  5I1V A;  2W3S A;  1N60 C;  2IPI A;  2I0K A;  5AWV A;  3FWA A;  2PLS A;  3EUB 3;  3VTE A;  2Y3R A;  3PQB A;  5G5H B;  3NS1 B;  2QPM A;  3TSJ A;  1DZN A;  3FW7 A;  2UUU A;  2P13 A;  2YVS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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