1E8HA

Structure of the h61t mutant of the flavoenzyme vanillyl-alcohol oxidase in the apo form complexed by adp
Total Genus 172
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
172
sequence length
555
structure length
545
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISMKPTHTHDPTHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPGGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Analysis of Flavinylation in Vanillyl-Alcohol Oxidase
pubmed doi rcsb
source organism Penicillium simplicissimum
molecule tags Oxidoreductase
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 172
structure length 545
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2000-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1e8hA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1e8hA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1e8hA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1e8hA03
3FW7A 2P3HA 2P4PA 1HSKA 1W1SA 3TSHA 1W1JA 2W55A 2R2ZA 3DEDA 1W1OA 3B9JB 3KJMA 3AM9A 3S1CA 1UXYA 2W3RA 3NS1B 3FW8A 1FO4A 4HG0A 3AMZA 2OAIA 4PVHA 3SR6B 3W8WA 4BC7A 1QLTA 1SB3B 1JROA 3DQ0A 4PYTA 1AHZA 3LLBA 4BBYA 4MLAA 3TSJA 2BVGA 3W8ZA 2GQTA 2QKNA 1DIIA 5AE3A 5FXPA 3I99A 1DIQA 4O95A 3S1EA 5FXFA 4PVJA 1WVFA 3PM9A 5FXEA 1FFVC 1N63C 2YVSA 1DZNA 1N5WC 2P13A 4OALA 2GQUA 3D2JA 5AE1A 5G5GB 2QPMA 2I0KA 1W1MA 3VTEA 2VFTA 3W8XA 4UD8A 2R8DA 1W1QA 1MBBA 1ZR6A 2O3GA 2VFSA 1FFUC 2VFUA 1AHUA 1N60C 4JAYA 1V97A 2EXRA 5HQXA 4DNSA 1JRPA 2E3TA 4ZOHB 5HHZA 3NVZB 2NQWA 4XLOA 1N5XA 1E8FA 3AN1A 2VAOA 1ZXIC 4ML8A 1RM6B 3BW7A 1MBTA 2VFRA 2AXRA 3TX1A 3D2DA 3NVWB 3C0PA 1VAOA 3JS8A 4PVEA 1I19A 2RK5A 1AHVA 3EUB3 1N61C 3LAEA 1WVEA 2BVHA 1FIQB 4PWCA 3FW9A 1E8GA 1E8HA 1N62C 1WYGA 4PVKA 3NVYB 4JB1A 3NRZB 4EC3A 1QLUA 4BC9A 1W1RA 1E0YA 5FXDA 2W3SA 5ADZA 1F0XA 3S1FA 2Q85A 1T3QC 4PZFA 5G5HB 2PLSA 5D79A 1W1LA 3GSYA 2VFVA 5AE2A 2Q4WA 2PLIA 4PWBA 4BCAA 3ETRB 3FWAA 1W1KA 3S1DA 1VDVA 2BVFA 5HMRA 3NVVB 2W54A 3D2HA 3HRDC 2MBRA
chains in the Genus database with same CATH superfamily
3EJEB 3FW7A 2P3HA 5L6FA 2P4PA 1HSKA 1W1SA 3TSHA 1W1JA 2W55A 2R2ZA 3DEDA 1W1OA 3B9JB 3EJDB 3KJMA 3AM9A 3S1CA 2Y4GA 1UXYA 2W3RA 3NS1B 3FW8A 1FO4A 4HG0A 3AMZA 2WDWA 2OAIA 4PVHA 3SR6B 3W8WA 2UUUA 4BC7A 1QLTA 1SB3B 1JROA 3DQ0A 4PYTA 1AHZA 3LLBA 4BBYA 3PQBA 4MLAA 3TSJA 5K8EA 2BVGA 3W8ZA 2GQTA 2QKNA 1DIIA 5AE3A 5FXPA 3I99A 1DIQA 4O95A 3S1EA 5FXFA 4PVJA 1WVFA 3PM9A 5FXEA 1FFVC 1N63C 2YVSA 1DZNA 1N5WC 2P13A 4OALA 2GQUA 3D2JA 5AE1A 5G5GB 2QPMA 3RJAA 2I0KA 1W1MA 3VTEA 2VFTA 3W8XA 5I1VA 4UD8A 2R8DA 1W1QA 1MBBA 1ZR6A 2O3GA 2VFSA 1FFUC 2VFUA 2Y3RA 1AHUA 1N60C 4JAYA 1V97A 2EXRA 5HQXA 4DNSA 1JRPA 2E3TA 4ZOHB 5HHZA 3NVZB 2NQWA 4XLOA 2IPIA 1N5XA 1E8FA 3AN1A 2VAOA 1ZXIC 4ML8A 1RM6B 3BW7A 2Y3SA 1MBTA 2VFRA 2AXRA 3TX1A 3D2DA 3NVWB 3C0PA 1VAOA 3JS8A 4PVEA 1I19A 3POPA 2RK5A 5I1WA 1AHVA 3EUB3 1N61C 3LAEA 1WVEA 2BVHA 5AWVA 5L6GA 1FIQB 4PWCA 3FW9A 1E8GA 3RJ8A 1E8HA 1N62C 1WYGA 3NVYB 4PVKA 4JB1A 3NRZB 4EC3A 1QLUA 4BC9A 1W1RA 1E0YA 5FXDA 2W3SA 5ADZA 1F0XA 3S1FA 2Q85A 1T3QC 4PZFA 5G5HB 2PLSA 3HSUA 2Y08A 5D79A 1W1LA 3GSYA 2VFVA 5AE2A 2Q4WA 2PLIA 2UUVA 4PWBA 4BCAA 3ETRB 3FWAA 1W1KA 3EJBB 3S1DA 1VDVA 2BVFA 5HMRA 3NVVB 2W54A 3D2HA 3HRDC 2MBRA
chains in the Genus database with same CATH topology
3FW7A 2P3HA 5L6FA 2P4PA 1HSKA 1W1SA 3TSHA 1W1JA 2W55A 2R2ZA 3DEDA 1W1OA 3B9JB 3KJMA 3AM9A 3S1CA 2Y4GA 1UXYA 2W3RA 3NS1B 3FW8A 1FO4A 4HG0A 3AMZA 2WDWA 2OAIA 4PVHA 3SR6B 3W8WA 2UUUA 4BC7A 1QLTA 1SB3B 1JROA 3DQ0A 4PYTA 1AHZA 3LLBA 4BBYA 3PQBA 4MLAA 3TSJA 5K8EA 2BVGA 3W8ZA 2GQTA 2QKNA 1DIIA 5AE3A 5FXPA 3I99A 1DIQA 4O95A 3S1EA 5FXFA 4PVJA 1WVFA 3PM9A 5FXEA 1FFVC 1N63C 2YVSA 1DZNA 1N5WC 2P13A 4OALA 2GQUA 3D2JA 5AE1A 5G5GB 2QPMA 3RJAA 2I0KA 1W1MA 3VTEA 2VFTA 3W8XA 5I1VA 4UD8A 2R8DA 1W1QA 1MBBA 1ZR6A 2O3GA 2VFSA 1FFUC 2VFUA 2Y3RA 1AHUA 1N60C 4JAYA 1V97A 2EXRA 5HQXA 4DNSA 1JRPA 2E3TA 4ZOHB 5HHZA 3NVZB 2NQWA 4XLOA 2IPIA 1N5XA 1E8FA 3AN1A 2VAOA 1ZXIC 4ML8A 1RM6B 3BW7A 2Y3SA 1MBTA 2VFRA 2AXRA 3TX1A 3D2DA 3NVWB 3C0PA 1VAOA 3JS8A 4PVEA 1I19A 3POPA 2RK5A 5I1WA 1AHVA 3EUB3 1N61C 3LAEA 1WVEA 2BVHA 5AWVA 5L6GA 1FIQB 4PWCA 3FW9A 1E8GA 3RJ8A 1E8HA 1N62C 1WYGA 4PVKA 3NVYB 4JB1A 3NRZB 4EC3A 1QLUA 4BC9A 1W1RA 1E0YA 5FXDA 2W3SA 5ADZA 1F0XA 3S1FA 2Q85A 1T3QC 4PZFA 5G5HB 2PLSA 3HSUA 2Y08A 5D79A 1W1LA 3GSYA 2VFVA 5AE2A 2Q4WA 2PLIA 2UUVA 4PWBA 4BCAA 3ETRB 3FWAA 1W1KA 3S1DA 1VDVA 2BVFA 5HMRA 3NVVB 2W54A 3D2HA 3HRDC 2MBRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FW7 A;  2P3H A;  2P4P A;  1HSK A;  1W1S A;  3TSH A;  1W1J A;  2W55 A;  2R2Z A;  3DED A;  1W1O A;  3B9J B;  3KJM A;  3AM9 A;  3S1C A;  1UXY A;  2W3R A;  3NS1 B;  3FW8 A;  1FO4 A;  4HG0 A;  3AMZ A;  2OAI A;  4PVH A;  3SR6 B;  3W8W A;  4BC7 A;  1QLT A;  1SB3 B;  1JRO A;  3DQ0 A;  4PYT A;  1AHZ A;  3LLB A;  4BBY A;  4MLA A;  3TSJ A;  2BVG A;  3W8Z A;  2GQT A;  2QKN A;  1DII A;  5AE3 A;  5FXP A;  3I99 A;  1DIQ A;  4O95 A;  3S1E A;  5FXF A;  4PVJ A;  1WVF A;  3PM9 A;  5FXE A;  1FFV C;  1N63 C;  2YVS A;  1DZN A;  1N5W C;  2P13 A;  4OAL A;  2GQU A;  3D2J A;  5AE1 A;  5G5G B;  2QPM A;  2I0K A;  1W1M A;  3VTE A;  2VFT A;  3W8X A;  4UD8 A;  2R8D A;  1W1Q A;  1MBB A;  1ZR6 A;  2O3G A;  2VFS A;  1FFU C;  2VFU A;  1AHU A;  1N60 C;  4JAY A;  1V97 A;  2EXR A;  5HQX A;  4DNS A;  1JRP A;  2E3T A;  4ZOH B;  5HHZ A;  3NVZ B;  2NQW A;  4XLO A;  1N5X A;  1E8F A;  3AN1 A;  2VAO A;  1ZXI C;  4ML8 A;  1RM6 B;  3BW7 A;  1MBT A;  2VFR A;  2AXR A;  3TX1 A;  3D2D A;  3NVW B;  3C0P A;  1VAO A;  3JS8 A;  4PVE A;  1I19 A;  2RK5 A;  1AHV A;  3EUB 3;  1N61 C;  3LAE A;  1WVE A;  2BVH A;  1FIQ B;  4PWC A;  3FW9 A;  1E8G A;  1E8H A;  1N62 C;  1WYG A;  4PVK A;  3NVY B;  4JB1 A;  3NRZ B;  4EC3 A;  1QLU A;  4BC9 A;  1W1R A;  1E0Y A;  5FXD A;  2W3S A;  5ADZ A;  1F0X A;  3S1F A;  2Q85 A;  1T3Q C;  4PZF A;  5G5H B;  2PLS A;  5D79 A;  1W1L A;  3GSY A;  2VFV A;  5AE2 A;  2Q4W A;  2PLI A;  4PWB A;  4BCA A;  3ETR B;  3FWA A;  1W1K A;  3S1D A;  1VDV A;  2BVF A;  5HMR A;  3NVV B;  2W54 A;  3D2H A;  3HRD C;  2MBR A; 
#chains in the Genus database with same CATH topology
 3EJE B;  3FW7 A;  2P3H A;  5L6F A;  2P4P A;  1HSK A;  1W1S A;  3TSH A;  1W1J A;  2W55 A;  2R2Z A;  3DED A;  1W1O A;  3B9J B;  3EJD B;  3KJM A;  3AM9 A;  3S1C A;  2Y4G A;  1UXY A;  2W3R A;  3NS1 B;  3FW8 A;  1FO4 A;  4HG0 A;  3AMZ A;  2WDW A;  2OAI A;  4PVH A;  3SR6 B;  3W8W A;  2UUU A;  4BC7 A;  1QLT A;  1SB3 B;  1JRO A;  3DQ0 A;  4PYT A;  1AHZ A;  3LLB A;  4BBY A;  3PQB A;  4MLA A;  3TSJ A;  5K8E A;  2BVG A;  3W8Z A;  2GQT A;  2QKN A;  1DII A;  5AE3 A;  5FXP A;  3I99 A;  1DIQ A;  4O95 A;  3S1E A;  5FXF A;  4PVJ A;  1WVF A;  3PM9 A;  5FXE A;  1FFV C;  1N63 C;  2YVS A;  1DZN A;  1N5W C;  2P13 A;  4OAL A;  2GQU A;  3D2J A;  5AE1 A;  5G5G B;  2QPM A;  3RJA A;  2I0K A;  1W1M A;  3VTE A;  2VFT A;  3W8X A;  5I1V A;  4UD8 A;  2R8D A;  1W1Q A;  1MBB A;  1ZR6 A;  2O3G A;  2VFS A;  1FFU C;  2VFU A;  2Y3R A;  1AHU A;  1N60 C;  4JAY A;  1V97 A;  2EXR A;  5HQX A;  4DNS A;  1JRP A;  2E3T A;  4ZOH B;  5HHZ A;  3NVZ B;  2NQW A;  4XLO A;  2IPI A;  1N5X A;  1E8F A;  3AN1 A;  2VAO A;  1ZXI C;  4ML8 A;  1RM6 B;  3BW7 A;  2Y3S A;  1MBT A;  2VFR A;  2AXR A;  3TX1 A;  3D2D A;  3NVW B;  3C0P A;  1VAO A;  3JS8 A;  4PVE A;  1I19 A;  3POP A;  2RK5 A;  5I1W A;  1AHV A;  3EUB 3;  1N61 C;  3LAE A;  1WVE A;  2BVH A;  5AWV A;  5L6G A;  1FIQ B;  4PWC A;  3FW9 A;  1E8G A;  3RJ8 A;  1E8H A;  1N62 C;  1WYG A;  3NVY B;  4PVK A;  4JB1 A;  3NRZ B;  4EC3 A;  1QLU A;  4BC9 A;  1W1R A;  1E0Y A;  5FXD A;  2W3S A;  5ADZ A;  1F0X A;  3S1F A;  2Q85 A;  1T3Q C;  4PZF A;  5G5H B;  2PLS A;  3HSU A;  2Y08 A;  5D79 A;  1W1L A;  3GSY A;  2VFV A;  5AE2 A;  2Q4W A;  2PLI A;  2UUV A;  4PWB A;  4BCA A;  3ETR B;  3FWA A;  1W1K A;  3EJB B;  3S1D A;  1VDV A;  2BVF A;  5HMR A;  3NVV B;  2W54 A;  3D2H A;  3HRD C;  2MBR A; 
#chains in the Genus database with same CATH homology
 3FW7 A;  2P3H A;  5L6F A;  2P4P A;  1HSK A;  1W1S A;  3TSH A;  1W1J A;  2W55 A;  2R2Z A;  3DED A;  1W1O A;  3B9J B;  3KJM A;  3AM9 A;  3S1C A;  2Y4G A;  1UXY A;  2W3R A;  3NS1 B;  3FW8 A;  1FO4 A;  4HG0 A;  3AMZ A;  2WDW A;  2OAI A;  4PVH A;  3SR6 B;  3W8W A;  2UUU A;  4BC7 A;  1QLT A;  1SB3 B;  1JRO A;  3DQ0 A;  4PYT A;  1AHZ A;  3LLB A;  4BBY A;  3PQB A;  4MLA A;  3TSJ A;  5K8E A;  2BVG A;  3W8Z A;  2GQT A;  2QKN A;  1DII A;  5AE3 A;  5FXP A;  3I99 A;  1DIQ A;  4O95 A;  3S1E A;  5FXF A;  4PVJ A;  1WVF A;  3PM9 A;  5FXE A;  1FFV C;  1N63 C;  2YVS A;  1DZN A;  1N5W C;  2P13 A;  4OAL A;  2GQU A;  3D2J A;  5AE1 A;  5G5G B;  2QPM A;  3RJA A;  2I0K A;  1W1M A;  3VTE A;  2VFT A;  3W8X A;  5I1V A;  4UD8 A;  2R8D A;  1W1Q A;  1MBB A;  1ZR6 A;  2O3G A;  2VFS A;  1FFU C;  2VFU A;  2Y3R A;  1AHU A;  1N60 C;  4JAY A;  1V97 A;  2EXR A;  5HQX A;  4DNS A;  1JRP A;  2E3T A;  4ZOH B;  5HHZ A;  3NVZ B;  2NQW A;  4XLO A;  2IPI A;  1N5X A;  1E8F A;  3AN1 A;  2VAO A;  1ZXI C;  4ML8 A;  1RM6 B;  3BW7 A;  2Y3S A;  1MBT A;  2VFR A;  2AXR A;  3TX1 A;  3D2D A;  3NVW B;  3C0P A;  1VAO A;  3JS8 A;  4PVE A;  1I19 A;  3POP A;  2RK5 A;  5I1W A;  1AHV A;  3EUB 3;  1N61 C;  3LAE A;  1WVE A;  2BVH A;  5AWV A;  5L6G A;  1FIQ B;  4PWC A;  3FW9 A;  1E8G A;  3RJ8 A;  1E8H A;  1N62 C;  1WYG A;  4PVK A;  3NVY B;  4JB1 A;  3NRZ B;  4EC3 A;  1QLU A;  4BC9 A;  1W1R A;  1E0Y A;  5FXD A;  2W3S A;  5ADZ A;  1F0X A;  3S1F A;  2Q85 A;  1T3Q C;  4PZF A;  5G5H B;  2PLS A;  3HSU A;  2Y08 A;  5D79 A;  1W1L A;  3GSY A;  2VFV A;  5AE2 A;  2Q4W A;  2PLI A;  2UUV A;  4PWB A;  4BCA A;  3ETR B;  3FWA A;  1W1K A;  3S1D A;  1VDV A;  2BVF A;  5HMR A;  3NVV B;  2W54 A;  3D2H A;  3HRD C;  2MBR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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