1AHVA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase in complex with 2-nitro-p-cresol
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
555
structure length
555
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISSKDQIVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
pubmed doi rcsb
molecule tags Flavoenzyme
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 165
structure length 555
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 1997-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1ahvA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1ahvA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1ahvA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1ahvA03
5FXEA 1W1MA 1DIIA 1WYGA 4PWBA 3GSYA 4UD8A 1N62C 4BC9A 3AN1A 4JB1A 1AHVA 2Q85A 1FO4A 2R8DA 3KJMA 3NVZB 1QLUA 1DZNA 5HQXA 5G5HB 2W3RA 1N63C 1HSKA 3AM9A 1WVEA 1FFVC 4PYTA 1N61C 1W1SA 3AMZA 2P13A 2PLIA 3NVYB 2QPMA 5ADZA 3TSJA 1N5WC 2YVSA 4PWCA 2OAIA 3NS1B 2R2ZA 3FW8A 5AE1A 1WVFA 1MBBA 1F0XA 3S1EA 1W1OA 2EXRA 2VFRA 2NQWA 4PZFA 3LAEA 5G5GB 2P4PA 4ZOHB 1I19A 2BVGA 1VDVA 3FWAA 1N60C 3ETRB 3PM9A 2Q4WA 1QLTA 5FXFA 3S1CA 2AXRA 1JRPA 1E8FA 3B9JB 3FW9A 4JAYA 3S1FA 1E8GA 4HG0A 3SR6B 1E8HA 3JS8A 1W1RA 2VFUA 2VFTA 3W8ZA 2W54A 5HHZA 5FXDA 1W1QA 3W8WA 3D2HA 5HMRA 1ZXIC 3LLBA 2O3GA 5FXPA 3BW7A 2RK5A 5AE3A 5AE2A 2VAOA 1RM6B 1W1KA 4DNSA 4XLOA 3NRZB 1W1JA 3EUB3 3D2JA 2BVFA 4O95A 1FIQB 3C0PA 1DIQA 4EC3A 4OALA 4PVKA 2GQTA 3VTEA 3W8XA 2W3SA 2W55A 4MLAA 3TSHA 1T3QC 2BVHA 1V97A 3NVWB 3FW7A 2VFVA 2QKNA 2PLSA 1E0YA 2E3TA 3HRDC 2I0KA 1VAOA 4BC7A 3DEDA 1AHUA 4BCAA 4PVHA 5D79A 1JROA 4PVEA 4PVJA 3TX1A 3NVVB 1N5XA 1MBTA 2GQUA 3I99A 3DQ0A 2VFSA 3D2DA 1ZR6A 3S1DA 1UXYA 2P3HA 1FFUC 1W1LA 4ML8A 1SB3B 4BBYA 2MBRA 1AHZA
chains in the Genus database with same CATH superfamily
3HSUA 3EJEB 2Y4GA 5FXEA 1W1MA 1DIIA 1WYGA 5L6GA 4PWBA 3GSYA 4UD8A 2UUUA 1N62C 4BC9A 3AN1A 4JB1A 1AHVA 2Q85A 1FO4A 2R8DA 3KJMA 3NVZB 1QLUA 1DZNA 5HQXA 5G5HB 2W3RA 1N63C 1HSKA 3AM9A 1WVEA 1FFVC 4PYTA 1N61C 1W1SA 3AMZA 2P13A 2PLIA 3NVYB 2QPMA 5ADZA 3TSJA 1N5WC 2YVSA 4PWCA 2OAIA 3NS1B 2R2ZA 3FW8A 5AE1A 1WVFA 1MBBA 1F0XA 3PQBA 5AWVA 2WDWA 3S1EA 1W1OA 2EXRA 2VFRA 2NQWA 4PZFA 3LAEA 5G5GB 2P4PA 4ZOHB 1I19A 2BVGA 1VDVA 3FWAA 1N60C 3ETRB 3PM9A 2Q4WA 1QLTA 5FXFA 3S1CA 2AXRA 2Y3RA 1JRPA 1E8FA 3B9JB 3FW9A 4JAYA 3S1FA 1E8GA 4HG0A 3SR6B 1E8HA 3JS8A 1W1RA 2VFUA 2VFTA 3W8ZA 2W54A 3EJDB 5HHZA 3POPA 5FXDA 1W1QA 5L6FA 3W8WA 3D2HA 5HMRA 1ZXIC 3LLBA 2O3GA 5FXPA 3BW7A 2RK5A 5AE3A 5AE2A 5I1WA 2VAOA 3RJAA 1RM6B 2Y3SA 1W1KA 4DNSA 5I1VA 4XLOA 3NRZB 1W1JA 3EUB3 3D2JA 2BVFA 4O95A 1FIQB 3RJ8A 3C0PA 1DIQA 4EC3A 4OALA 4PVKA 5K8EA 2Y08A 2GQTA 3VTEA 3W8XA 2W3SA 2W55A 4MLAA 3TSHA 1T3QC 2BVHA 1V97A 3NVWB 3FW7A 2VFVA 3EJBB 2QKNA 2PLSA 1E0YA 2E3TA 3HRDC 2I0KA 1VAOA 4BC7A 3DEDA 1AHUA 4BCAA 4PVHA 2UUVA 5D79A 1JROA 4PVEA 4PVJA 3TX1A 3NVVB 1N5XA 1MBTA 2GQUA 3I99A 3DQ0A 2VFSA 3D2DA 1ZR6A 3S1DA 1UXYA 2P3HA 1FFUC 2IPIA 1W1LA 4ML8A 1SB3B 4BBYA 2MBRA 1AHZA
chains in the Genus database with same CATH topology
3HSUA 2Y4GA 5FXEA 1W1MA 1DIIA 1WYGA 5L6GA 4PWBA 3GSYA 4UD8A 2UUUA 1N62C 4BC9A 3AN1A 4JB1A 1AHVA 2Q85A 1FO4A 2R8DA 3KJMA 3NVZB 1QLUA 1DZNA 5HQXA 5G5HB 2W3RA 1N63C 1HSKA 3AM9A 1WVEA 1FFVC 4PYTA 1N61C 1W1SA 3AMZA 2P13A 2PLIA 3NVYB 2QPMA 5ADZA 3TSJA 1N5WC 2YVSA 4PWCA 2OAIA 3NS1B 2R2ZA 3FW8A 5AE1A 1WVFA 1MBBA 1F0XA 3PQBA 5AWVA 2WDWA 3S1EA 1W1OA 2EXRA 2VFRA 2NQWA 4PZFA 3LAEA 5G5GB 2P4PA 4ZOHB 1I19A 2BVGA 1VDVA 3FWAA 1N60C 3ETRB 3PM9A 2Q4WA 1QLTA 5FXFA 3S1CA 2AXRA 2Y3RA 1JRPA 1E8FA 3B9JB 3FW9A 4JAYA 3S1FA 1E8GA 4HG0A 3SR6B 1E8HA 3JS8A 1W1RA 2VFUA 2VFTA 3W8ZA 2W54A 5HHZA 3POPA 5FXDA 1W1QA 5L6FA 3W8WA 3D2HA 5HMRA 1ZXIC 3LLBA 2O3GA 5FXPA 3BW7A 2RK5A 5AE3A 5AE2A 5I1WA 2VAOA 3RJAA 1RM6B 2Y3SA 1W1KA 4DNSA 5I1VA 4XLOA 3NRZB 1W1JA 3EUB3 3D2JA 2BVFA 4O95A 1FIQB 3RJ8A 3C0PA 1DIQA 4EC3A 4OALA 4PVKA 5K8EA 2Y08A 2GQTA 3VTEA 3W8XA 2W3SA 2W55A 4MLAA 3TSHA 1T3QC 2BVHA 1V97A 3NVWB 3FW7A 2VFVA 2QKNA 2PLSA 1E0YA 2E3TA 3HRDC 2I0KA 1VAOA 4BC7A 3DEDA 1AHUA 4BCAA 4PVHA 2UUVA 5D79A 1JROA 4PVEA 4PVJA 3TX1A 3NVVB 1N5XA 1MBTA 2GQUA 3I99A 3DQ0A 2VFSA 3D2DA 1ZR6A 3S1DA 1UXYA 2P3HA 1FFUC 2IPIA 1W1LA 4ML8A 1SB3B 4BBYA 2MBRA 1AHZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FXE A;  1W1M A;  1DII A;  1WYG A;  4PWB A;  3GSY A;  4UD8 A;  1N62 C;  4BC9 A;  3AN1 A;  4JB1 A;  1AHV A;  2Q85 A;  1FO4 A;  2R8D A;  3KJM A;  3NVZ B;  1QLU A;  1DZN A;  5HQX A;  5G5H B;  2W3R A;  1N63 C;  1HSK A;  3AM9 A;  1WVE A;  1FFV C;  4PYT A;  1N61 C;  1W1S A;  3AMZ A;  2P13 A;  2PLI A;  3NVY B;  2QPM A;  5ADZ A;  3TSJ A;  1N5W C;  2YVS A;  4PWC A;  2OAI A;  3NS1 B;  2R2Z A;  3FW8 A;  5AE1 A;  1WVF A;  1MBB A;  1F0X A;  3S1E A;  1W1O A;  2EXR A;  2VFR A;  2NQW A;  4PZF A;  3LAE A;  5G5G B;  2P4P A;  4ZOH B;  1I19 A;  2BVG A;  1VDV A;  3FWA A;  1N60 C;  3ETR B;  3PM9 A;  2Q4W A;  1QLT A;  5FXF A;  3S1C A;  2AXR A;  1JRP A;  1E8F A;  3B9J B;  3FW9 A;  4JAY A;  3S1F A;  1E8G A;  4HG0 A;  3SR6 B;  1E8H A;  3JS8 A;  1W1R A;  2VFU A;  2VFT A;  3W8Z A;  2W54 A;  5HHZ A;  5FXD A;  1W1Q A;  3W8W A;  3D2H A;  5HMR A;  1ZXI C;  3LLB A;  2O3G A;  5FXP A;  3BW7 A;  2RK5 A;  5AE3 A;  5AE2 A;  2VAO A;  1RM6 B;  1W1K A;  4DNS A;  4XLO A;  3NRZ B;  1W1J A;  3EUB 3;  3D2J A;  2BVF A;  4O95 A;  1FIQ B;  3C0P A;  1DIQ A;  4EC3 A;  4OAL A;  4PVK A;  2GQT A;  3VTE A;  3W8X A;  2W3S A;  2W55 A;  4MLA A;  3TSH A;  1T3Q C;  2BVH A;  1V97 A;  3NVW B;  3FW7 A;  2VFV A;  2QKN A;  2PLS A;  1E0Y A;  2E3T A;  3HRD C;  2I0K A;  1VAO A;  4BC7 A;  3DED A;  1AHU A;  4BCA A;  4PVH A;  5D79 A;  1JRO A;  4PVE A;  4PVJ A;  3TX1 A;  3NVV B;  1N5X A;  1MBT A;  2GQU A;  3I99 A;  3DQ0 A;  2VFS A;  3D2D A;  1ZR6 A;  3S1D A;  1UXY A;  2P3H A;  1FFU C;  1W1L A;  4ML8 A;  1SB3 B;  4BBY A;  2MBR A;  1AHZ A; 
#chains in the Genus database with same CATH topology
 3HSU A;  3EJE B;  2Y4G A;  5FXE A;  1W1M A;  1DII A;  1WYG A;  5L6G A;  4PWB A;  3GSY A;  4UD8 A;  2UUU A;  1N62 C;  4BC9 A;  3AN1 A;  4JB1 A;  1AHV A;  2Q85 A;  1FO4 A;  2R8D A;  3KJM A;  3NVZ B;  1QLU A;  1DZN A;  5HQX A;  5G5H B;  2W3R A;  1N63 C;  1HSK A;  3AM9 A;  1WVE A;  1FFV C;  4PYT A;  1N61 C;  1W1S A;  3AMZ A;  2P13 A;  2PLI A;  3NVY B;  2QPM A;  5ADZ A;  3TSJ A;  1N5W C;  2YVS A;  4PWC A;  2OAI A;  3NS1 B;  2R2Z A;  3FW8 A;  5AE1 A;  1WVF A;  1MBB A;  1F0X A;  3PQB A;  5AWV A;  2WDW A;  3S1E A;  1W1O A;  2EXR A;  2VFR A;  2NQW A;  4PZF A;  3LAE A;  5G5G B;  2P4P A;  4ZOH B;  1I19 A;  2BVG A;  1VDV A;  3FWA A;  1N60 C;  3ETR B;  3PM9 A;  2Q4W A;  1QLT A;  5FXF A;  3S1C A;  2AXR A;  2Y3R A;  1JRP A;  1E8F A;  3B9J B;  3FW9 A;  4JAY A;  3S1F A;  1E8G A;  4HG0 A;  3SR6 B;  1E8H A;  3JS8 A;  1W1R A;  2VFU A;  2VFT A;  3W8Z A;  2W54 A;  3EJD B;  5HHZ A;  3POP A;  5FXD A;  1W1Q A;  5L6F A;  3W8W A;  3D2H A;  5HMR A;  1ZXI C;  3LLB A;  2O3G A;  5FXP A;  3BW7 A;  2RK5 A;  5AE3 A;  5AE2 A;  5I1W A;  2VAO A;  3RJA A;  1RM6 B;  2Y3S A;  1W1K A;  4DNS A;  5I1V A;  4XLO A;  3NRZ B;  1W1J A;  3EUB 3;  3D2J A;  2BVF A;  4O95 A;  1FIQ B;  3RJ8 A;  3C0P A;  1DIQ A;  4EC3 A;  4OAL A;  4PVK A;  5K8E A;  2Y08 A;  2GQT A;  3VTE A;  3W8X A;  2W3S A;  2W55 A;  4MLA A;  3TSH A;  1T3Q C;  2BVH A;  1V97 A;  3NVW B;  3FW7 A;  2VFV A;  3EJB B;  2QKN A;  2PLS A;  1E0Y A;  2E3T A;  3HRD C;  2I0K A;  1VAO A;  4BC7 A;  3DED A;  1AHU A;  4BCA A;  4PVH A;  2UUV A;  5D79 A;  1JRO A;  4PVE A;  4PVJ A;  3TX1 A;  3NVV B;  1N5X A;  1MBT A;  2GQU A;  3I99 A;  3DQ0 A;  2VFS A;  3D2D A;  1ZR6 A;  3S1D A;  1UXY A;  2P3H A;  1FFU C;  2IPI A;  1W1L A;  4ML8 A;  1SB3 B;  4BBY A;  2MBR A;  1AHZ A; 
#chains in the Genus database with same CATH homology
 3HSU A;  2Y4G A;  5FXE A;  1W1M A;  1DII A;  1WYG A;  5L6G A;  4PWB A;  3GSY A;  4UD8 A;  2UUU A;  1N62 C;  4BC9 A;  3AN1 A;  4JB1 A;  1AHV A;  2Q85 A;  1FO4 A;  2R8D A;  3KJM A;  3NVZ B;  1QLU A;  1DZN A;  5HQX A;  5G5H B;  2W3R A;  1N63 C;  1HSK A;  3AM9 A;  1WVE A;  1FFV C;  4PYT A;  1N61 C;  1W1S A;  3AMZ A;  2P13 A;  2PLI A;  3NVY B;  2QPM A;  5ADZ A;  3TSJ A;  1N5W C;  2YVS A;  4PWC A;  2OAI A;  3NS1 B;  2R2Z A;  3FW8 A;  5AE1 A;  1WVF A;  1MBB A;  1F0X A;  3PQB A;  5AWV A;  2WDW A;  3S1E A;  1W1O A;  2EXR A;  2VFR A;  2NQW A;  4PZF A;  3LAE A;  5G5G B;  2P4P A;  4ZOH B;  1I19 A;  2BVG A;  1VDV A;  3FWA A;  1N60 C;  3ETR B;  3PM9 A;  2Q4W A;  1QLT A;  5FXF A;  3S1C A;  2AXR A;  2Y3R A;  1JRP A;  1E8F A;  3B9J B;  3FW9 A;  4JAY A;  3S1F A;  1E8G A;  4HG0 A;  3SR6 B;  1E8H A;  3JS8 A;  1W1R A;  2VFU A;  2VFT A;  3W8Z A;  2W54 A;  5HHZ A;  3POP A;  5FXD A;  1W1Q A;  5L6F A;  3W8W A;  3D2H A;  5HMR A;  1ZXI C;  3LLB A;  2O3G A;  5FXP A;  3BW7 A;  2RK5 A;  5AE3 A;  5AE2 A;  5I1W A;  2VAO A;  3RJA A;  1RM6 B;  2Y3S A;  1W1K A;  4DNS A;  5I1V A;  4XLO A;  3NRZ B;  1W1J A;  3EUB 3;  3D2J A;  2BVF A;  4O95 A;  1FIQ B;  3RJ8 A;  3C0P A;  1DIQ A;  4EC3 A;  4OAL A;  4PVK A;  5K8E A;  2Y08 A;  2GQT A;  3VTE A;  3W8X A;  2W3S A;  2W55 A;  4MLA A;  3TSH A;  1T3Q C;  2BVH A;  1V97 A;  3NVW B;  3FW7 A;  2VFV A;  2QKN A;  2PLS A;  1E0Y A;  2E3T A;  3HRD C;  2I0K A;  1VAO A;  4BC7 A;  3DED A;  1AHU A;  4BCA A;  4PVH A;  2UUV A;  5D79 A;  1JRO A;  4PVE A;  4PVJ A;  3TX1 A;  3NVV B;  1N5X A;  1MBT A;  2GQU A;  3I99 A;  3DQ0 A;  2VFS A;  3D2D A;  1ZR6 A;  3S1D A;  1UXY A;  2P3H A;  1FFU C;  2IPI A;  1W1L A;  4ML8 A;  1SB3 B;  4BBY A;  2MBR A;  1AHZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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