1DIIA

Crystal structure of p-cresol methylhydroxylase at 2.5 a resolution
Total Genus 180
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
sequence length
515
structure length
515
Chain Sequence
AVLPKGVTQGEFNKAVQKFRALLGDDNVLVESDQLVPYNKIMMPVENAAHAPSAAVTATTVEQVQGVVKICNEHKIPIWTISTGRNFGYGSAAPVQRGQVILDLKKMNKIIKIDPEMCYALVEPGVTFGQMYDYIQENNLPVMLSFSAPSAIAGPVGNTMDRGVGYTPYGEHFMMQCGMEVVLANGDVYRTGMGGVPGSNTWQIFKWGYGPTLDGMFTQANYGICTKMGFWLMPKPPVFKPFEVIFEDEADIVEIVDALRPLRMSNTIPNSVVIASTLWEAGSAHLTRAQYTTEPGHTPDSVIKQMQKDTGMGAWNLYAALYGTQEQVDVNWKIVTDVFKKLGKGRIVTQEEAGDTQPFKYRAQLMSGVPNLQEFGLYNWRGGGGSMWFAPVSEARGSECKKQAAMAKRVLHKYGLDYVAEFIVAPRDMHHVIDVLYDRTNPEETKRADACFNELLDEFEKEGYAVYRVNTRFQDRVAQSYGPVKRKLEHAIKRAVDPNNILAPGRSGIDLNNDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structures of the flavocytochrome p-cresol methylhydroxylase and its enzyme-substrate complex: gated substrate entry and proton relays support the proposed catalytic mechanism.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords P-CRESOL METHYLHYDROXYLASE
total genus 180
structure length 515
sequence length 515
chains with identical sequence B
ec nomenclature ec 1.17.9.1: 4-methylphenol dehydrogenase (hydroxylating).
pdb deposition date 1999-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1diiA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1diiA02
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1diiA03
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1diiA01
1AHVA 3S1CA 3W8ZA 3NS1B 2VFTA 4BBYA 2BVHA 3NVWB 4BC7A 2MBRA 4UD8A 5HHZA 1JROA 5FXEA 1I19A 1V97A 4BCAA 3TSHA 2W54A 1W1MA 5FXPA 4JAYA 4OALA 4PVEA 4PZFA 2P13A 1W1SA 1W1JA 2YVSA 5AE2A 2GQUA 1DIIA 3AMZA 1VDVA 1WVEA 1FFVC 3EUB3 4PVKA 4MLAA 2P4PA 3FWAA 3HRDC 2PLSA 2QPMA 4BC9A 2AXRA 1AHZA 2PLIA 1WVFA 2W3SA 3NVZB 5ADZA 2NQWA 2OAIA 1UXYA 4ML8A 2I0KA 2E3TA 2QKNA 1JRPA 5AE3A 2VFUA 1ZR6A 3S1EA 2O3GA 2Q4WA 3LLBA 3FW9A 1AHUA 3NVVB 3NVYB 2BVFA 3PM9A 4ZOHB 1VAOA 1W1KA 1E8FA 1MBBA 2EXRA 1QLTA 3ETRB 5FXFA 4HG0A 3FW7A 5G5HB 2R8DA 1N63C 2R2ZA 3W8WA 1W1LA 1E8HA 1QLUA 1W1QA 3S1DA 5FXDA 2W3RA 3BW7A 2W55A 3C0PA 5AE1A 5HMRA 2GQTA 3DEDA 2VFSA 1T3QC 1N62C 3GSYA 2VFVA 3D2HA 1N60C 3KJMA 4EC3A 3TX1A 4PYTA 1RM6B 1N5XA 1SB3B 1DZNA 1MBTA 3I99A 4PVJA 3VTEA 2P3HA 1HSKA 1ZXIC 5D79A 4PWBA 2RK5A 3NRZB 4PWCA 3B9JB 4DNSA 2Q85A 4O95A 5HQXA 1E8GA 3D2JA 2BVGA 3AN1A 1F0XA 1N61C 3FW8A 4XLOA 3AM9A 3JS8A 5G5GB 1FFUC 1N5WC 2VAOA 1FO4A 1FIQB 1W1OA 3D2DA 3W8XA 3SR6B 1E0YA 3DQ0A 3S1FA 4JB1A 1DIQA 3LAEA 4PVHA 1WYGA 3TSJA 2VFRA 1W1RA
chains in the Genus database with same CATH superfamily
1AHVA 3S1CA 3W8ZA 3NS1B 2VFTA 4BBYA 2BVHA 3NVWB 4BC7A 5AWVA 2MBRA 4UD8A 5HHZA 1JROA 5FXEA 3RJ8A 1I19A 1V97A 4BCAA 3TSHA 2W54A 1W1MA 5FXPA 4JAYA 4OALA 4PVEA 4PZFA 2P13A 1W1SA 1W1JA 2YVSA 5AE2A 2GQUA 1DIIA 3AMZA 1VDVA 1WVEA 1FFVC 3EUB3 4PVKA 4MLAA 2P4PA 3FWAA 3HRDC 2PLSA 2QPMA 4BC9A 2AXRA 1AHZA 2PLIA 3EJDB 1WVFA 2W3SA 3NVZB 5ADZA 2NQWA 2OAIA 1UXYA 2UUUA 4ML8A 2I0KA 2E3TA 2QKNA 1JRPA 5AE3A 2VFUA 1ZR6A 3S1EA 2O3GA 2Q4WA 3LLBA 3FW9A 1AHUA 3NVVB 2UUVA 2Y4GA 3NVYB 2BVFA 3PM9A 5I1WA 4ZOHB 1VAOA 1W1KA 1E8FA 1MBBA 2EXRA 1QLTA 3ETRB 5L6FA 5FXFA 4HG0A 2IPIA 3FW7A 5G5HB 5K8EA 2R8DA 2Y08A 1N63C 2R2ZA 3W8WA 1W1LA 1E8HA 1QLUA 1W1QA 3S1DA 5FXDA 2W3RA 3BW7A 2W55A 3C0PA 5AE1A 5HMRA 2GQTA 3DEDA 2VFSA 1T3QC 1N62C 3GSYA 2VFVA 3D2HA 1N60C 3KJMA 2Y3RA 4EC3A 3TX1A 4PYTA 1RM6B 3PQBA 1N5XA 1SB3B 1DZNA 1MBTA 3I99A 4PVJA 3VTEA 2P3HA 3RJAA 5I1VA 1HSKA 1ZXIC 3POPA 5D79A 4PWBA 2Y3SA 2RK5A 3NRZB 4PWCA 3B9JB 4DNSA 3HSUA 2Q85A 4O95A 5HQXA 1E8GA 3D2JA 2BVGA 3AN1A 1F0XA 1N61C 3FW8A 4XLOA 2WDWA 3AM9A 3JS8A 5G5GB 1FFUC 1N5WC 2VAOA 5L6GA 1FO4A 1FIQB 1W1OA 3D2DA 3W8XA 3SR6B 3EJEB 1E0YA 3DQ0A 3S1FA 4JB1A 1DIQA 3LAEA 3EJBB 4PVHA 1WYGA 3TSJA 2VFRA 1W1RA
chains in the Genus database with same CATH topology
1AHVA 3S1CA 3W8ZA 3NS1B 2VFTA 4BBYA 2BVHA 3NVWB 4BC7A 5AWVA 2MBRA 4UD8A 5HHZA 1JROA 5FXEA 3RJ8A 1I19A 1V97A 4BCAA 3TSHA 2W54A 1W1MA 5FXPA 4JAYA 4OALA 4PVEA 4PZFA 2P13A 1W1SA 1W1JA 2YVSA 5AE2A 2GQUA 1DIIA 3AMZA 1VDVA 1WVEA 1FFVC 3EUB3 4PVKA 4MLAA 2P4PA 3FWAA 3HRDC 2PLSA 2QPMA 4BC9A 2AXRA 1AHZA 2PLIA 1WVFA 2W3SA 3NVZB 5ADZA 2NQWA 2OAIA 1UXYA 2UUUA 4ML8A 2I0KA 2E3TA 2QKNA 1JRPA 5AE3A 2VFUA 1ZR6A 3S1EA 2O3GA 2Q4WA 3LLBA 3FW9A 1AHUA 3NVVB 2UUVA 2Y4GA 3NVYB 2BVFA 3PM9A 5I1WA 4ZOHB 1VAOA 1W1KA 1E8FA 1MBBA 2EXRA 1QLTA 3ETRB 5L6FA 5FXFA 4HG0A 2IPIA 3FW7A 5G5HB 5K8EA 2R8DA 2Y08A 1N63C 2R2ZA 3W8WA 1W1LA 1E8HA 1QLUA 1W1QA 3S1DA 5FXDA 2W3RA 3BW7A 2W55A 3C0PA 5AE1A 5HMRA 2GQTA 3DEDA 2VFSA 1T3QC 1N62C 3GSYA 2VFVA 3D2HA 1N60C 3KJMA 2Y3RA 4EC3A 3TX1A 4PYTA 1RM6B 3PQBA 1N5XA 1SB3B 1DZNA 1MBTA 3I99A 4PVJA 3VTEA 2P3HA 3RJAA 5I1VA 1HSKA 1ZXIC 3POPA 5D79A 4PWBA 2Y3SA 2RK5A 3NRZB 4PWCA 3B9JB 4DNSA 3HSUA 2Q85A 4O95A 5HQXA 1E8GA 3D2JA 2BVGA 3AN1A 1F0XA 1N61C 3FW8A 4XLOA 2WDWA 3AM9A 3JS8A 5G5GB 1FFUC 1N5WC 2VAOA 5L6GA 1FO4A 1FIQB 1W1OA 3D2DA 3W8XA 3SR6B 1E0YA 3DQ0A 3S1FA 4JB1A 1DIQA 3LAEA 4PVHA 1WYGA 3TSJA 2VFRA 1W1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AHV A;  3S1C A;  3W8Z A;  3NS1 B;  2VFT A;  4BBY A;  2BVH A;  3NVW B;  4BC7 A;  2MBR A;  4UD8 A;  5HHZ A;  1JRO A;  5FXE A;  1I19 A;  1V97 A;  4BCA A;  3TSH A;  2W54 A;  1W1M A;  5FXP A;  4JAY A;  4OAL A;  4PVE A;  4PZF A;  2P13 A;  1W1S A;  1W1J A;  2YVS A;  5AE2 A;  2GQU A;  1DII A;  3AMZ A;  1VDV A;  1WVE A;  1FFV C;  3EUB 3;  4PVK A;  4MLA A;  2P4P A;  3FWA A;  3HRD C;  2PLS A;  2QPM A;  4BC9 A;  2AXR A;  1AHZ A;  2PLI A;  1WVF A;  2W3S A;  3NVZ B;  5ADZ A;  2NQW A;  2OAI A;  1UXY A;  4ML8 A;  2I0K A;  2E3T A;  2QKN A;  1JRP A;  5AE3 A;  2VFU A;  1ZR6 A;  3S1E A;  2O3G A;  2Q4W A;  3LLB A;  3FW9 A;  1AHU A;  3NVV B;  3NVY B;  2BVF A;  3PM9 A;  4ZOH B;  1VAO A;  1W1K A;  1E8F A;  1MBB A;  2EXR A;  1QLT A;  3ETR B;  5FXF A;  4HG0 A;  3FW7 A;  5G5H B;  2R8D A;  1N63 C;  2R2Z A;  3W8W A;  1W1L A;  1E8H A;  1QLU A;  1W1Q A;  3S1D A;  5FXD A;  2W3R A;  3BW7 A;  2W55 A;  3C0P A;  5AE1 A;  5HMR A;  2GQT A;  3DED A;  2VFS A;  1T3Q C;  1N62 C;  3GSY A;  2VFV A;  3D2H A;  1N60 C;  3KJM A;  4EC3 A;  3TX1 A;  4PYT A;  1RM6 B;  1N5X A;  1SB3 B;  1DZN A;  1MBT A;  3I99 A;  4PVJ A;  3VTE A;  2P3H A;  1HSK A;  1ZXI C;  5D79 A;  4PWB A;  2RK5 A;  3NRZ B;  4PWC A;  3B9J B;  4DNS A;  2Q85 A;  4O95 A;  5HQX A;  1E8G A;  3D2J A;  2BVG A;  3AN1 A;  1F0X A;  1N61 C;  3FW8 A;  4XLO A;  3AM9 A;  3JS8 A;  5G5G B;  1FFU C;  1N5W C;  2VAO A;  1FO4 A;  1FIQ B;  1W1O A;  3D2D A;  3W8X A;  3SR6 B;  1E0Y A;  3DQ0 A;  3S1F A;  4JB1 A;  1DIQ A;  3LAE A;  4PVH A;  1WYG A;  3TSJ A;  2VFR A;  1W1R A; 
#chains in the Genus database with same CATH topology
 1AHV A;  3S1C A;  3W8Z A;  3NS1 B;  2VFT A;  4BBY A;  2BVH A;  3NVW B;  4BC7 A;  5AWV A;  2MBR A;  4UD8 A;  5HHZ A;  1JRO A;  5FXE A;  3RJ8 A;  1I19 A;  1V97 A;  4BCA A;  3TSH A;  2W54 A;  1W1M A;  5FXP A;  4JAY A;  4OAL A;  4PVE A;  4PZF A;  2P13 A;  1W1S A;  1W1J A;  2YVS A;  5AE2 A;  2GQU A;  1DII A;  3AMZ A;  1VDV A;  1WVE A;  1FFV C;  3EUB 3;  4PVK A;  4MLA A;  2P4P A;  3FWA A;  3HRD C;  2PLS A;  2QPM A;  4BC9 A;  2AXR A;  1AHZ A;  2PLI A;  3EJD B;  1WVF A;  2W3S A;  3NVZ B;  5ADZ A;  2NQW A;  2OAI A;  1UXY A;  2UUU A;  4ML8 A;  2I0K A;  2E3T A;  2QKN A;  1JRP A;  5AE3 A;  2VFU A;  1ZR6 A;  3S1E A;  2O3G A;  2Q4W A;  3LLB A;  3FW9 A;  1AHU A;  3NVV B;  2UUV A;  2Y4G A;  3NVY B;  2BVF A;  3PM9 A;  5I1W A;  4ZOH B;  1VAO A;  1W1K A;  1E8F A;  1MBB A;  2EXR A;  1QLT A;  3ETR B;  5L6F A;  5FXF A;  4HG0 A;  2IPI A;  3FW7 A;  5G5H B;  5K8E A;  2R8D A;  2Y08 A;  1N63 C;  2R2Z A;  3W8W A;  1W1L A;  1E8H A;  1QLU A;  1W1Q A;  3S1D A;  5FXD A;  2W3R A;  3BW7 A;  2W55 A;  3C0P A;  5AE1 A;  5HMR A;  2GQT A;  3DED A;  2VFS A;  1T3Q C;  1N62 C;  3GSY A;  2VFV A;  3D2H A;  1N60 C;  3KJM A;  2Y3R A;  4EC3 A;  3TX1 A;  4PYT A;  1RM6 B;  3PQB A;  1N5X A;  1SB3 B;  1DZN A;  1MBT A;  3I99 A;  4PVJ A;  3VTE A;  2P3H A;  3RJA A;  5I1V A;  1HSK A;  1ZXI C;  3POP A;  5D79 A;  4PWB A;  2Y3S A;  2RK5 A;  3NRZ B;  4PWC A;  3B9J B;  4DNS A;  3HSU A;  2Q85 A;  4O95 A;  5HQX A;  1E8G A;  3D2J A;  2BVG A;  3AN1 A;  1F0X A;  1N61 C;  3FW8 A;  4XLO A;  2WDW A;  3AM9 A;  3JS8 A;  5G5G B;  1FFU C;  1N5W C;  2VAO A;  5L6G A;  1FO4 A;  1FIQ B;  1W1O A;  3D2D A;  3W8X A;  3SR6 B;  3EJE B;  1E0Y A;  3DQ0 A;  3S1F A;  4JB1 A;  1DIQ A;  3LAE A;  3EJB B;  4PVH A;  1WYG A;  3TSJ A;  2VFR A;  1W1R A; 
#chains in the Genus database with same CATH homology
 1AHV A;  3S1C A;  3W8Z A;  3NS1 B;  2VFT A;  4BBY A;  2BVH A;  3NVW B;  4BC7 A;  5AWV A;  2MBR A;  4UD8 A;  5HHZ A;  1JRO A;  5FXE A;  3RJ8 A;  1I19 A;  1V97 A;  4BCA A;  3TSH A;  2W54 A;  1W1M A;  5FXP A;  4JAY A;  4OAL A;  4PVE A;  4PZF A;  2P13 A;  1W1S A;  1W1J A;  2YVS A;  5AE2 A;  2GQU A;  1DII A;  3AMZ A;  1VDV A;  1WVE A;  1FFV C;  3EUB 3;  4PVK A;  4MLA A;  2P4P A;  3FWA A;  3HRD C;  2PLS A;  2QPM A;  4BC9 A;  2AXR A;  1AHZ A;  2PLI A;  1WVF A;  2W3S A;  3NVZ B;  5ADZ A;  2NQW A;  2OAI A;  1UXY A;  2UUU A;  4ML8 A;  2I0K A;  2E3T A;  2QKN A;  1JRP A;  5AE3 A;  2VFU A;  1ZR6 A;  3S1E A;  2O3G A;  2Q4W A;  3LLB A;  3FW9 A;  1AHU A;  3NVV B;  2UUV A;  2Y4G A;  3NVY B;  2BVF A;  3PM9 A;  5I1W A;  4ZOH B;  1VAO A;  1W1K A;  1E8F A;  1MBB A;  2EXR A;  1QLT A;  3ETR B;  5L6F A;  5FXF A;  4HG0 A;  2IPI A;  3FW7 A;  5G5H B;  5K8E A;  2R8D A;  2Y08 A;  1N63 C;  2R2Z A;  3W8W A;  1W1L A;  1E8H A;  1QLU A;  1W1Q A;  3S1D A;  5FXD A;  2W3R A;  3BW7 A;  2W55 A;  3C0P A;  5AE1 A;  5HMR A;  2GQT A;  3DED A;  2VFS A;  1T3Q C;  1N62 C;  3GSY A;  2VFV A;  3D2H A;  1N60 C;  3KJM A;  2Y3R A;  4EC3 A;  3TX1 A;  4PYT A;  1RM6 B;  3PQB A;  1N5X A;  1SB3 B;  1DZN A;  1MBT A;  3I99 A;  4PVJ A;  3VTE A;  2P3H A;  3RJA A;  5I1V A;  1HSK A;  1ZXI C;  3POP A;  5D79 A;  4PWB A;  2Y3S A;  2RK5 A;  3NRZ B;  4PWC A;  3B9J B;  4DNS A;  3HSU A;  2Q85 A;  4O95 A;  5HQX A;  1E8G A;  3D2J A;  2BVG A;  3AN1 A;  1F0X A;  1N61 C;  3FW8 A;  4XLO A;  2WDW A;  3AM9 A;  3JS8 A;  5G5G B;  1FFU C;  1N5W C;  2VAO A;  5L6G A;  1FO4 A;  1FIQ B;  1W1O A;  3D2D A;  3W8X A;  3SR6 B;  1E0Y A;  3DQ0 A;  3S1F A;  4JB1 A;  1DIQ A;  3LAE A;  4PVH A;  1WYG A;  3TSJ A;  2VFR A;  1W1R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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