1E0YA

Structure of the d170s/t457e double mutant of vanillyl-alcohol oxidase
Total Genus 178
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
178
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPSLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPGGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGEFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Inversion of Stereospecificity in Vanillyl-Alcohol Oxidase
pubmed doi rcsb
molecule tags Flavoenzyme
source organism Penicillium simplicissimum
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 178
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2000-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1e0yA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1e0yA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1e0yA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1e0yA03
3FWAA 1UXYA 4JB1A 1DIIA 3B9JB 4BC7A 3TSHA 2VFUA 3NVZB 2EXRA 1JROA 3AN1A 3TSJA 3AMZA 1N61C 3JS8A 2W55A 2P4PA 2YVSA 1E8GA 4EC3A 1N5WC 2W54A 4BC9A 4OALA 1VAOA 2R2ZA 2MBRA 3S1CA 3W8WA 4PZFA 3NRZB 1JRPA 1AHUA 2VFRA 3NVWB 3PM9A 2Q85A 1VDVA 1FIQB 3SR6B 4PWBA 1E8HA 3D2DA 1AHZA 2W3SA 2BVHA 1HSKA 1QLTA 1W1SA 3C0PA 4PVKA 2R8DA 2PLSA 1N62C 3TX1A 3LLBA 5G5GB 5FXDA 1W1RA 1W1QA 2GQUA 3D2JA 5FXEA 3BW7A 3FW9A 3S1DA 1W1LA 1V97A 3AM9A 2VFTA 1MBTA 4ML8A 1T3QC 5ADZA 1I19A 1W1OA 1SB3B 2O3GA 2I0KA 2Q4WA 2AXRA 2QPMA 3EUB3 3VTEA 1N60C 2E3TA 3ETRB 2VFSA 1AHVA 1F0XA 3FW7A 3D2HA 3HRDC 1WVEA 4PYTA 3S1FA 3DQ0A 5G5HB 5AE1A 3GSYA 1DIQA 2VAOA 4MLAA 5HQXA 5HHZA 3DEDA 1QLUA 4UD8A 1FFVC 1FFUC 1N63C 1FO4A 4ZOHB 5HMRA 1ZR6A 4HG0A 2P13A 3NS1B 2P3HA 1DZNA 4PVJA 1W1JA 1WYGA 4XLOA 3I99A 5AE2A 2W3RA 2RK5A 1N5XA 3KJMA 2OAIA 2NQWA 2QKNA 3FW8A 1RM6B 2BVFA 4BCAA 1E0YA 3W8XA 2PLIA 1W1MA 2GQTA 4DNSA 2VFVA 2BVGA 3LAEA 3NVVB 5D79A 4PVEA 3S1EA 4PVHA 1MBBA 1WVFA 4BBYA 4O95A 1E8FA 1W1KA 3NVYB 5FXPA 3W8ZA 5FXFA 4JAYA 4PWCA 1ZXIC 5AE3A
chains in the Genus database with same CATH superfamily
3FWAA 1UXYA 5K8EA 4JB1A 1DIIA 3B9JB 4BC7A 3EJEB 3TSHA 2VFUA 3NVZB 2EXRA 1JROA 3AN1A 3TSJA 3AMZA 1N61C 3JS8A 2W55A 2P4PA 2YVSA 1E8GA 4EC3A 5I1WA 1N5WC 2W54A 4BC9A 4OALA 1VAOA 3EJDB 2R2ZA 2MBRA 3S1CA 3W8WA 4PZFA 3NRZB 1JRPA 1AHUA 2VFRA 3NVWB 3PM9A 2Q85A 1VDVA 3POPA 1FIQB 3SR6B 4PWBA 1E8HA 3D2DA 1AHZA 2W3SA 2BVHA 1HSKA 1QLTA 1W1SA 3C0PA 4PVKA 2R8DA 2PLSA 1N62C 5AWVA 3TX1A 3LLBA 5G5GB 5FXDA 1W1RA 1W1QA 2GQUA 3D2JA 5FXEA 3BW7A 3FW9A 3S1DA 1W1LA 1V97A 3AM9A 2VFTA 2Y4GA 1MBTA 4ML8A 1T3QC 5ADZA 1I19A 1W1OA 1SB3B 2O3GA 2I0KA 2Q4WA 2AXRA 2QPMA 3EUB3 3VTEA 3EJBB 1N60C 2E3TA 3ETRB 2VFSA 1AHVA 1F0XA 3FW7A 2WDWA 3D2HA 3HRDC 1WVEA 4PYTA 2Y08A 3S1FA 2UUUA 3DQ0A 5G5HB 3RJAA 5L6GA 5AE1A 3GSYA 1DIQA 2VAOA 4MLAA 5HQXA 5HHZA 3DEDA 1QLUA 4UD8A 1FFVC 1FFUC 3PQBA 1N63C 1FO4A 4ZOHB 2IPIA 5HMRA 1ZR6A 4HG0A 2P13A 2UUVA 3NS1B 2Y3RA 2P3HA 1DZNA 4PVJA 1W1JA 1WYGA 4XLOA 3I99A 5AE2A 2W3RA 2RK5A 1N5XA 3KJMA 2OAIA 2NQWA 2QKNA 3FW8A 1RM6B 2BVFA 4BCAA 1E0YA 3W8XA 2PLIA 1W1MA 2GQTA 4DNSA 2VFVA 2Y3SA 2BVGA 3NVVB 3HSUA 5D79A 3LAEA 4PVEA 3S1EA 4PVHA 1MBBA 1WVFA 4BBYA 5I1VA 4O95A 1E8FA 1W1KA 3NVYB 5FXPA 3W8ZA 5FXFA 4JAYA 4PWCA 1ZXIC 3RJ8A 5AE3A 5L6FA
chains in the Genus database with same CATH topology
3FWAA 1UXYA 5K8EA 4JB1A 1DIIA 3B9JB 4BC7A 3TSHA 2VFUA 3NVZB 2EXRA 1JROA 3AN1A 3TSJA 3AMZA 1N61C 3JS8A 2W55A 2P4PA 2YVSA 1E8GA 4EC3A 5I1WA 1N5WC 2W54A 4BC9A 4OALA 1VAOA 2R2ZA 2MBRA 3S1CA 3W8WA 4PZFA 3NRZB 1JRPA 1AHUA 2VFRA 3NVWB 3PM9A 2Q85A 1VDVA 3POPA 1FIQB 3SR6B 4PWBA 1E8HA 3D2DA 1AHZA 2W3SA 2BVHA 1HSKA 1QLTA 1W1SA 3C0PA 4PVKA 2R8DA 2PLSA 1N62C 5AWVA 3TX1A 3LLBA 5G5GB 5FXDA 1W1RA 1W1QA 2GQUA 3D2JA 5FXEA 3BW7A 3FW9A 3S1DA 1W1LA 1V97A 3AM9A 2VFTA 2Y4GA 1MBTA 4ML8A 1T3QC 5ADZA 1I19A 1W1OA 1SB3B 2O3GA 2I0KA 2Q4WA 2AXRA 2QPMA 3EUB3 3VTEA 1N60C 2E3TA 3ETRB 2VFSA 1AHVA 1F0XA 3FW7A 2WDWA 3D2HA 3HRDC 1WVEA 4PYTA 2Y08A 3S1FA 2UUUA 3DQ0A 5G5HB 3RJAA 5L6GA 5AE1A 3GSYA 1DIQA 2VAOA 4MLAA 5HQXA 5HHZA 3DEDA 1QLUA 4UD8A 1FFVC 1FFUC 3PQBA 1N63C 1FO4A 4ZOHB 2IPIA 5HMRA 1ZR6A 4HG0A 2P13A 2UUVA 3NS1B 2Y3RA 2P3HA 1DZNA 4PVJA 1W1JA 1WYGA 4XLOA 3I99A 5AE2A 2W3RA 2RK5A 1N5XA 3KJMA 2OAIA 2NQWA 2QKNA 3FW8A 1RM6B 2BVFA 4BCAA 1E0YA 3W8XA 2PLIA 1W1MA 2GQTA 4DNSA 2VFVA 2Y3SA 2BVGA 3LAEA 3HSUA 5D79A 3NVVB 4PVEA 3S1EA 4PVHA 1MBBA 1WVFA 4BBYA 5I1VA 4O95A 1E8FA 1W1KA 3NVYB 5FXPA 3W8ZA 5FXFA 4JAYA 4PWCA 1ZXIC 3RJ8A 5AE3A 5L6FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FWA A;  1UXY A;  4JB1 A;  1DII A;  3B9J B;  4BC7 A;  3TSH A;  2VFU A;  3NVZ B;  2EXR A;  1JRO A;  3AN1 A;  3TSJ A;  3AMZ A;  1N61 C;  3JS8 A;  2W55 A;  2P4P A;  2YVS A;  1E8G A;  4EC3 A;  1N5W C;  2W54 A;  4BC9 A;  4OAL A;  1VAO A;  2R2Z A;  2MBR A;  3S1C A;  3W8W A;  4PZF A;  3NRZ B;  1JRP A;  1AHU A;  2VFR A;  3NVW B;  3PM9 A;  2Q85 A;  1VDV A;  1FIQ B;  3SR6 B;  4PWB A;  1E8H A;  3D2D A;  1AHZ A;  2W3S A;  2BVH A;  1HSK A;  1QLT A;  1W1S A;  3C0P A;  4PVK A;  2R8D A;  2PLS A;  1N62 C;  3TX1 A;  3LLB A;  5G5G B;  5FXD A;  1W1R A;  1W1Q A;  2GQU A;  3D2J A;  5FXE A;  3BW7 A;  3FW9 A;  3S1D A;  1W1L A;  1V97 A;  3AM9 A;  2VFT A;  1MBT A;  4ML8 A;  1T3Q C;  5ADZ A;  1I19 A;  1W1O A;  1SB3 B;  2O3G A;  2I0K A;  2Q4W A;  2AXR A;  2QPM A;  3EUB 3;  3VTE A;  1N60 C;  2E3T A;  3ETR B;  2VFS A;  1AHV A;  1F0X A;  3FW7 A;  3D2H A;  3HRD C;  1WVE A;  4PYT A;  3S1F A;  3DQ0 A;  5G5H B;  5AE1 A;  3GSY A;  1DIQ A;  2VAO A;  4MLA A;  5HQX A;  5HHZ A;  3DED A;  1QLU A;  4UD8 A;  1FFV C;  1FFU C;  1N63 C;  1FO4 A;  4ZOH B;  5HMR A;  1ZR6 A;  4HG0 A;  2P13 A;  3NS1 B;  2P3H A;  1DZN A;  4PVJ A;  1W1J A;  1WYG A;  4XLO A;  3I99 A;  5AE2 A;  2W3R A;  2RK5 A;  1N5X A;  3KJM A;  2OAI A;  2NQW A;  2QKN A;  3FW8 A;  1RM6 B;  2BVF A;  4BCA A;  1E0Y A;  3W8X A;  2PLI A;  1W1M A;  2GQT A;  4DNS A;  2VFV A;  2BVG A;  3LAE A;  3NVV B;  5D79 A;  4PVE A;  3S1E A;  4PVH A;  1MBB A;  1WVF A;  4BBY A;  4O95 A;  1E8F A;  1W1K A;  3NVY B;  5FXP A;  3W8Z A;  5FXF A;  4JAY A;  4PWC A;  1ZXI C;  5AE3 A; 
#chains in the Genus database with same CATH topology
 3FWA A;  1UXY A;  5K8E A;  4JB1 A;  1DII A;  3B9J B;  4BC7 A;  3EJE B;  3TSH A;  2VFU A;  3NVZ B;  2EXR A;  1JRO A;  3AN1 A;  3TSJ A;  3AMZ A;  1N61 C;  3JS8 A;  2W55 A;  2P4P A;  2YVS A;  1E8G A;  4EC3 A;  5I1W A;  1N5W C;  2W54 A;  4BC9 A;  4OAL A;  1VAO A;  3EJD B;  2R2Z A;  2MBR A;  3S1C A;  3W8W A;  4PZF A;  3NRZ B;  1JRP A;  1AHU A;  2VFR A;  3NVW B;  3PM9 A;  2Q85 A;  1VDV A;  3POP A;  1FIQ B;  3SR6 B;  4PWB A;  1E8H A;  3D2D A;  1AHZ A;  2W3S A;  2BVH A;  1HSK A;  1QLT A;  1W1S A;  3C0P A;  4PVK A;  2R8D A;  2PLS A;  1N62 C;  5AWV A;  3TX1 A;  3LLB A;  5G5G B;  5FXD A;  1W1R A;  1W1Q A;  2GQU A;  3D2J A;  5FXE A;  3BW7 A;  3FW9 A;  3S1D A;  1W1L A;  1V97 A;  3AM9 A;  2VFT A;  2Y4G A;  1MBT A;  4ML8 A;  1T3Q C;  5ADZ A;  1I19 A;  1W1O A;  1SB3 B;  2O3G A;  2I0K A;  2Q4W A;  2AXR A;  2QPM A;  3EUB 3;  3VTE A;  3EJB B;  1N60 C;  2E3T A;  3ETR B;  2VFS A;  1AHV A;  1F0X A;  3FW7 A;  2WDW A;  3D2H A;  3HRD C;  1WVE A;  4PYT A;  2Y08 A;  3S1F A;  2UUU A;  3DQ0 A;  5G5H B;  3RJA A;  5L6G A;  5AE1 A;  3GSY A;  1DIQ A;  2VAO A;  4MLA A;  5HQX A;  5HHZ A;  3DED A;  1QLU A;  4UD8 A;  1FFV C;  1FFU C;  3PQB A;  1N63 C;  1FO4 A;  4ZOH B;  2IPI A;  5HMR A;  1ZR6 A;  4HG0 A;  2P13 A;  2UUV A;  3NS1 B;  2Y3R A;  2P3H A;  1DZN A;  4PVJ A;  1W1J A;  1WYG A;  4XLO A;  3I99 A;  5AE2 A;  2W3R A;  2RK5 A;  1N5X A;  3KJM A;  2OAI A;  2NQW A;  2QKN A;  3FW8 A;  1RM6 B;  2BVF A;  4BCA A;  1E0Y A;  3W8X A;  2PLI A;  1W1M A;  2GQT A;  4DNS A;  2VFV A;  2Y3S A;  2BVG A;  3NVV B;  3HSU A;  5D79 A;  3LAE A;  4PVE A;  3S1E A;  4PVH A;  1MBB A;  1WVF A;  4BBY A;  5I1V A;  4O95 A;  1E8F A;  1W1K A;  3NVY B;  5FXP A;  3W8Z A;  5FXF A;  4JAY A;  4PWC A;  1ZXI C;  3RJ8 A;  5AE3 A;  5L6F A; 
#chains in the Genus database with same CATH homology
 3FWA A;  1UXY A;  5K8E A;  4JB1 A;  1DII A;  3B9J B;  4BC7 A;  3TSH A;  2VFU A;  3NVZ B;  2EXR A;  1JRO A;  3AN1 A;  3TSJ A;  3AMZ A;  1N61 C;  3JS8 A;  2W55 A;  2P4P A;  2YVS A;  1E8G A;  4EC3 A;  5I1W A;  1N5W C;  2W54 A;  4BC9 A;  4OAL A;  1VAO A;  2R2Z A;  2MBR A;  3S1C A;  3W8W A;  4PZF A;  3NRZ B;  1JRP A;  1AHU A;  2VFR A;  3NVW B;  3PM9 A;  2Q85 A;  1VDV A;  3POP A;  1FIQ B;  3SR6 B;  4PWB A;  1E8H A;  3D2D A;  1AHZ A;  2W3S A;  2BVH A;  1HSK A;  1QLT A;  1W1S A;  3C0P A;  4PVK A;  2R8D A;  2PLS A;  1N62 C;  5AWV A;  3TX1 A;  3LLB A;  5G5G B;  5FXD A;  1W1R A;  1W1Q A;  2GQU A;  3D2J A;  5FXE A;  3BW7 A;  3FW9 A;  3S1D A;  1W1L A;  1V97 A;  3AM9 A;  2VFT A;  2Y4G A;  1MBT A;  4ML8 A;  1T3Q C;  5ADZ A;  1I19 A;  1W1O A;  1SB3 B;  2O3G A;  2I0K A;  2Q4W A;  2AXR A;  2QPM A;  3EUB 3;  3VTE A;  1N60 C;  2E3T A;  3ETR B;  2VFS A;  1AHV A;  1F0X A;  3FW7 A;  2WDW A;  3D2H A;  3HRD C;  1WVE A;  4PYT A;  2Y08 A;  3S1F A;  2UUU A;  3DQ0 A;  5G5H B;  3RJA A;  5L6G A;  5AE1 A;  3GSY A;  1DIQ A;  2VAO A;  4MLA A;  5HQX A;  5HHZ A;  3DED A;  1QLU A;  4UD8 A;  1FFV C;  1FFU C;  3PQB A;  1N63 C;  1FO4 A;  4ZOH B;  2IPI A;  5HMR A;  1ZR6 A;  4HG0 A;  2P13 A;  2UUV A;  3NS1 B;  2Y3R A;  2P3H A;  1DZN A;  4PVJ A;  1W1J A;  1WYG A;  4XLO A;  3I99 A;  5AE2 A;  2W3R A;  2RK5 A;  1N5X A;  3KJM A;  2OAI A;  2NQW A;  2QKN A;  3FW8 A;  1RM6 B;  2BVF A;  4BCA A;  1E0Y A;  3W8X A;  2PLI A;  1W1M A;  2GQT A;  4DNS A;  2VFV A;  2Y3S A;  2BVG A;  3LAE A;  3HSU A;  5D79 A;  3NVV B;  4PVE A;  3S1E A;  4PVH A;  1MBB A;  1WVF A;  4BBY A;  5I1V A;  4O95 A;  1E8F A;  1W1K A;  3NVY B;  5FXP A;  3W8Z A;  5FXF A;  4JAY A;  4PWC A;  1ZXI C;  3RJ8 A;  5AE3 A;  5L6F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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