1HSKA

Crystal structure of s. aureus murb
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
303
structure length
303
Chain Sequence
NKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISLLSLDHIEVSDDAIIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQGSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIGEHPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A structural variation for MurB: X-ray crystal structure of Staphylococcus aureus UDP-N-acetylenolpyruvylglucosamine reductase (MurB).
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Staphylococcus aureus
molecule keywords UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE
total genus 98
structure length 303
sequence length 303
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2000-12-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1hskA02
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1hskA01
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 1hskA03
2R2ZA 1AHVA 1FIQB 3BW7A 3HRDC 3NVZB 1MBTA 3DEDA 2MBRA 2W55A 4PWCA 1W1OA 1E8HA 2GQTA 3S1DA 1N60C 1WYGA 1FO4A 1FFVC 1W1JA 2OAIA 2P4PA 1N62C 2BVHA 3NVWB 3AMZA 1W1RA 4UD8A 3C0PA 1SB3B 4DNSA 5G5GB 1ZXIC 2PLSA 4JB1A 3W8WA 2VFTA 3GSYA 3TX1A 2GQUA 1AHUA 2PLIA 2W3RA 3DQ0A 2QPMA 3D2HA 1T3QC 1I19A 3KJMA 2EXRA 3NRZB 5FXPA 4ML8A 4PVEA 5FXEA 2O3GA 2Q4WA 1QLUA 5G5HB 3S1EA 5ADZA 1VAOA 1HSKA 4BBYA 3FW8A 5FXDA 1JROA 3NS1B 5HHZA 1FFUC 1RM6B 5AE3A 1AHZA 2VFUA 1ZR6A 3S1CA 2Q85A 1DIQA 2P3HA 2I0KA 2VFSA 4PVHA 2NQWA 3I99A 1MBBA 2AXRA 1V97A 5HQXA 3FW7A 3B9JB 1W1SA 1W1MA 3TSHA 3EUB3 3NVVB 1N61C 1F0XA 4OALA 1UXYA 3W8ZA 4BCAA 2YVSA 3ETRB 2VAOA 1N5WC 4O95A 2VFRA 4EC3A 5D79A 3W8XA 2W54A 1QLTA 1N63C 1WVFA 2W3SA 3SR6B 4BC9A 4PVKA 2R8DA 4MLAA 3D2DA 3NVYB 3FW9A 1WVEA 1W1QA 4HG0A 2E3TA 2QKNA 4PYTA 1E0YA 5FXFA 3JS8A 4PVJA 2RK5A 4JAYA 2BVGA 2VFVA 1JRPA 3AM9A 3FWAA 1E8GA 3D2JA 1W1LA 3AN1A 4XLOA 3TSJA 1E8FA 1N5XA 3PM9A 1W1KA 4BC7A 5AE1A 3VTEA 4PZFA 3S1FA 2BVFA 1VDVA 1DZNA 1DIIA 4ZOHB 4PWBA 3LLBA 5AE2A 3LAEA 5HMRA 2P13A
chains in the Genus database with same CATH superfamily
2R2ZA 1AHVA 1FIQB 3BW7A 3HRDC 3NVZB 1MBTA 3DEDA 2MBRA 2W55A 4PWCA 1W1OA 1E8HA 2GQTA 3S1DA 1N60C 1WYGA 1FO4A 1FFVC 1W1JA 2OAIA 2P4PA 1N62C 2BVHA 3NVWB 5I1WA 3AMZA 1W1RA 4UD8A 5L6FA 3C0PA 1SB3B 4DNSA 5G5GB 1ZXIC 3POPA 2PLSA 4JB1A 3W8WA 2VFTA 3GSYA 3TX1A 2GQUA 1AHUA 2PLIA 2W3RA 3DQ0A 2QPMA 3D2HA 1T3QC 1I19A 3KJMA 2Y3RA 2EXRA 3NRZB 5FXPA 4ML8A 4PVEA 2UUUA 3HSUA 5FXEA 2O3GA 5L6GA 2Q4WA 1QLUA 2UUVA 5G5HB 2Y3SA 3S1EA 3EJDB 5ADZA 1VAOA 1HSKA 4BBYA 3FW8A 5FXDA 1JROA 3NS1B 5HHZA 1FFUC 1RM6B 5AE3A 1AHZA 2VFUA 1ZR6A 3S1CA 2Q85A 1DIQA 2P3HA 2I0KA 2VFSA 4PVHA 2NQWA 3I99A 2Y4GA 5K8EA 1MBBA 3PQBA 2AXRA 1V97A 5HQXA 3FW7A 3B9JB 1W1SA 1W1MA 3TSHA 3EUB3 3NVVB 1N61C 1F0XA 4OALA 1UXYA 3W8ZA 4BCAA 2YVSA 3ETRB 2VAOA 1N5WC 4O95A 2VFRA 4EC3A 5D79A 3W8XA 2W54A 1QLTA 1N63C 1WVFA 2W3SA 3SR6B 3EJBB 4BC9A 2WDWA 4PVKA 2IPIA 2R8DA 4MLAA 3D2DA 3NVYB 3FW9A 1WVEA 1W1QA 4HG0A 2E3TA 2QKNA 4PYTA 1E0YA 5FXFA 3JS8A 4PVJA 2RK5A 3RJ8A 4JAYA 2BVGA 2VFVA 1JRPA 3AM9A 3FWAA 1E8GA 3D2JA 1W1LA 3AN1A 4XLOA 3TSJA 1E8FA 5I1VA 1N5XA 3PM9A 1W1KA 4BC7A 5AWVA 5AE1A 3VTEA 4PZFA 2Y08A 3S1FA 2BVFA 1VDVA 1DZNA 1DIIA 4ZOHB 4PWBA 3LLBA 3EJEB 3RJAA 5AE2A 3LAEA 5HMRA 2P13A
chains in the Genus database with same CATH topology
2R2ZA 1AHVA 1FIQB 3BW7A 3HRDC 3NVZB 1MBTA 3DEDA 2MBRA 2W55A 4PWCA 1W1OA 1E8HA 2GQTA 3S1DA 1N60C 1WYGA 1FO4A 1FFVC 1W1JA 2OAIA 2P4PA 1N62C 2BVHA 3NVWB 5I1WA 3AMZA 1W1RA 4UD8A 5L6FA 3C0PA 1SB3B 4DNSA 5G5GB 1ZXIC 3POPA 2PLSA 4JB1A 3W8WA 2VFTA 3GSYA 3TX1A 2GQUA 1AHUA 2PLIA 2W3RA 3DQ0A 2QPMA 3D2HA 1T3QC 1I19A 3KJMA 2Y3RA 2EXRA 3NRZB 5FXPA 4ML8A 4PVEA 2UUUA 3HSUA 5FXEA 2O3GA 5L6GA 2Q4WA 1QLUA 2UUVA 5G5HB 2Y3SA 3S1EA 5ADZA 1VAOA 1HSKA 4BBYA 3FW8A 5FXDA 1JROA 3NS1B 5HHZA 1FFUC 1RM6B 5AE3A 1AHZA 2VFUA 1ZR6A 3S1CA 2Q85A 1DIQA 2P3HA 2I0KA 2VFSA 4PVHA 2NQWA 3I99A 2Y4GA 5K8EA 1MBBA 3PQBA 2AXRA 1V97A 5HQXA 3FW7A 3B9JB 1W1SA 1W1MA 3TSHA 3EUB3 3NVVB 1N61C 1F0XA 4OALA 1UXYA 3W8ZA 4BCAA 2YVSA 3ETRB 2VAOA 1N5WC 4O95A 2VFRA 4EC3A 5D79A 3W8XA 2W54A 1QLTA 1N63C 1WVFA 2W3SA 3SR6B 2WDWA 4BC9A 4PVKA 2IPIA 2R8DA 4MLAA 3D2DA 3NVYB 3FW9A 1WVEA 1W1QA 4HG0A 2E3TA 2QKNA 4PYTA 1E0YA 5FXFA 3JS8A 4PVJA 2RK5A 3RJ8A 4JAYA 2BVGA 2VFVA 1JRPA 3AM9A 3FWAA 1E8GA 3D2JA 1W1LA 3AN1A 4XLOA 3TSJA 1E8FA 5I1VA 1N5XA 3PM9A 1W1KA 4BC7A 5AWVA 5AE1A 3VTEA 4PZFA 2Y08A 3S1FA 2BVFA 1VDVA 1DZNA 1DIIA 4ZOHB 4PWBA 3LLBA 3RJAA 5AE2A 3LAEA 5HMRA 2P13A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R2Z A;  1AHV A;  1FIQ B;  3BW7 A;  3HRD C;  3NVZ B;  1MBT A;  3DED A;  2MBR A;  2W55 A;  4PWC A;  1W1O A;  1E8H A;  2GQT A;  3S1D A;  1N60 C;  1WYG A;  1FO4 A;  1FFV C;  1W1J A;  2OAI A;  2P4P A;  1N62 C;  2BVH A;  3NVW B;  3AMZ A;  1W1R A;  4UD8 A;  3C0P A;  1SB3 B;  4DNS A;  5G5G B;  1ZXI C;  2PLS A;  4JB1 A;  3W8W A;  2VFT A;  3GSY A;  3TX1 A;  2GQU A;  1AHU A;  2PLI A;  2W3R A;  3DQ0 A;  2QPM A;  3D2H A;  1T3Q C;  1I19 A;  3KJM A;  2EXR A;  3NRZ B;  5FXP A;  4ML8 A;  4PVE A;  5FXE A;  2O3G A;  2Q4W A;  1QLU A;  5G5H B;  3S1E A;  5ADZ A;  1VAO A;  1HSK A;  4BBY A;  3FW8 A;  5FXD A;  1JRO A;  3NS1 B;  5HHZ A;  1FFU C;  1RM6 B;  5AE3 A;  1AHZ A;  2VFU A;  1ZR6 A;  3S1C A;  2Q85 A;  1DIQ A;  2P3H A;  2I0K A;  2VFS A;  4PVH A;  2NQW A;  3I99 A;  1MBB A;  2AXR A;  1V97 A;  5HQX A;  3FW7 A;  3B9J B;  1W1S A;  1W1M A;  3TSH A;  3EUB 3;  3NVV B;  1N61 C;  1F0X A;  4OAL A;  1UXY A;  3W8Z A;  4BCA A;  2YVS A;  3ETR B;  2VAO A;  1N5W C;  4O95 A;  2VFR A;  4EC3 A;  5D79 A;  3W8X A;  2W54 A;  1QLT A;  1N63 C;  1WVF A;  2W3S A;  3SR6 B;  4BC9 A;  4PVK A;  2R8D A;  4MLA A;  3D2D A;  3NVY B;  3FW9 A;  1WVE A;  1W1Q A;  4HG0 A;  2E3T A;  2QKN A;  4PYT A;  1E0Y A;  5FXF A;  3JS8 A;  4PVJ A;  2RK5 A;  4JAY A;  2BVG A;  2VFV A;  1JRP A;  3AM9 A;  3FWA A;  1E8G A;  3D2J A;  1W1L A;  3AN1 A;  4XLO A;  3TSJ A;  1E8F A;  1N5X A;  3PM9 A;  1W1K A;  4BC7 A;  5AE1 A;  3VTE A;  4PZF A;  3S1F A;  2BVF A;  1VDV A;  1DZN A;  1DII A;  4ZOH B;  4PWB A;  3LLB A;  5AE2 A;  3LAE A;  5HMR A;  2P13 A; 
#chains in the Genus database with same CATH topology
 2R2Z A;  1AHV A;  1FIQ B;  3BW7 A;  3HRD C;  3NVZ B;  1MBT A;  3DED A;  2MBR A;  2W55 A;  4PWC A;  1W1O A;  1E8H A;  2GQT A;  3S1D A;  1N60 C;  1WYG A;  1FO4 A;  1FFV C;  1W1J A;  2OAI A;  2P4P A;  1N62 C;  2BVH A;  3NVW B;  5I1W A;  3AMZ A;  1W1R A;  4UD8 A;  5L6F A;  3C0P A;  1SB3 B;  4DNS A;  5G5G B;  1ZXI C;  3POP A;  2PLS A;  4JB1 A;  3W8W A;  2VFT A;  3GSY A;  3TX1 A;  2GQU A;  1AHU A;  2PLI A;  2W3R A;  3DQ0 A;  2QPM A;  3D2H A;  1T3Q C;  1I19 A;  3KJM A;  2Y3R A;  2EXR A;  3NRZ B;  5FXP A;  4ML8 A;  4PVE A;  2UUU A;  3HSU A;  5FXE A;  2O3G A;  5L6G A;  2Q4W A;  1QLU A;  2UUV A;  5G5H B;  2Y3S A;  3S1E A;  3EJD B;  5ADZ A;  1VAO A;  1HSK A;  4BBY A;  3FW8 A;  5FXD A;  1JRO A;  3NS1 B;  5HHZ A;  1FFU C;  1RM6 B;  5AE3 A;  1AHZ A;  2VFU A;  1ZR6 A;  3S1C A;  2Q85 A;  1DIQ A;  2P3H A;  2I0K A;  2VFS A;  4PVH A;  2NQW A;  3I99 A;  2Y4G A;  5K8E A;  1MBB A;  3PQB A;  2AXR A;  1V97 A;  5HQX A;  3FW7 A;  3B9J B;  1W1S A;  1W1M A;  3TSH A;  3EUB 3;  3NVV B;  1N61 C;  1F0X A;  4OAL A;  1UXY A;  3W8Z A;  4BCA A;  2YVS A;  3ETR B;  2VAO A;  1N5W C;  4O95 A;  2VFR A;  4EC3 A;  5D79 A;  3W8X A;  2W54 A;  1QLT A;  1N63 C;  1WVF A;  2W3S A;  3SR6 B;  3EJB B;  4BC9 A;  2WDW A;  4PVK A;  2IPI A;  2R8D A;  4MLA A;  3D2D A;  3NVY B;  3FW9 A;  1WVE A;  1W1Q A;  4HG0 A;  2E3T A;  2QKN A;  4PYT A;  1E0Y A;  5FXF A;  3JS8 A;  4PVJ A;  2RK5 A;  3RJ8 A;  4JAY A;  2BVG A;  2VFV A;  1JRP A;  3AM9 A;  3FWA A;  1E8G A;  3D2J A;  1W1L A;  3AN1 A;  4XLO A;  3TSJ A;  1E8F A;  5I1V A;  1N5X A;  3PM9 A;  1W1K A;  4BC7 A;  5AWV A;  5AE1 A;  3VTE A;  4PZF A;  2Y08 A;  3S1F A;  2BVF A;  1VDV A;  1DZN A;  1DII A;  4ZOH B;  4PWB A;  3LLB A;  3EJE B;  3RJA A;  5AE2 A;  3LAE A;  5HMR A;  2P13 A; 
#chains in the Genus database with same CATH homology
 2R2Z A;  1AHV A;  1FIQ B;  3BW7 A;  3HRD C;  3NVZ B;  1MBT A;  3DED A;  2MBR A;  2W55 A;  4PWC A;  1W1O A;  1E8H A;  2GQT A;  3S1D A;  1N60 C;  1WYG A;  1FO4 A;  1FFV C;  1W1J A;  2OAI A;  2P4P A;  1N62 C;  2BVH A;  3NVW B;  5I1W A;  3AMZ A;  1W1R A;  4UD8 A;  5L6F A;  3C0P A;  1SB3 B;  4DNS A;  5G5G B;  1ZXI C;  3POP A;  2PLS A;  4JB1 A;  3W8W A;  2VFT A;  3GSY A;  3TX1 A;  2GQU A;  1AHU A;  2PLI A;  2W3R A;  3DQ0 A;  2QPM A;  3D2H A;  1T3Q C;  1I19 A;  3KJM A;  2Y3R A;  2EXR A;  3NRZ B;  5FXP A;  4ML8 A;  4PVE A;  2UUU A;  3HSU A;  5FXE A;  2O3G A;  5L6G A;  2Q4W A;  1QLU A;  2UUV A;  5G5H B;  2Y3S A;  3S1E A;  5ADZ A;  1VAO A;  1HSK A;  4BBY A;  3FW8 A;  5FXD A;  1JRO A;  3NS1 B;  5HHZ A;  1FFU C;  1RM6 B;  5AE3 A;  1AHZ A;  2VFU A;  1ZR6 A;  3S1C A;  2Q85 A;  1DIQ A;  2P3H A;  2I0K A;  2VFS A;  4PVH A;  2NQW A;  3I99 A;  2Y4G A;  5K8E A;  1MBB A;  3PQB A;  2AXR A;  1V97 A;  5HQX A;  3FW7 A;  3B9J B;  1W1S A;  1W1M A;  3TSH A;  3EUB 3;  3NVV B;  1N61 C;  1F0X A;  4OAL A;  1UXY A;  3W8Z A;  4BCA A;  2YVS A;  3ETR B;  2VAO A;  1N5W C;  4O95 A;  2VFR A;  4EC3 A;  5D79 A;  3W8X A;  2W54 A;  1QLT A;  1N63 C;  1WVF A;  2W3S A;  3SR6 B;  2WDW A;  4BC9 A;  4PVK A;  2IPI A;  2R8D A;  4MLA A;  3D2D A;  3NVY B;  3FW9 A;  1WVE A;  1W1Q A;  4HG0 A;  2E3T A;  2QKN A;  4PYT A;  1E0Y A;  5FXF A;  3JS8 A;  4PVJ A;  2RK5 A;  3RJ8 A;  4JAY A;  2BVG A;  2VFV A;  1JRP A;  3AM9 A;  3FWA A;  1E8G A;  3D2J A;  1W1L A;  3AN1 A;  4XLO A;  3TSJ A;  1E8F A;  5I1V A;  1N5X A;  3PM9 A;  1W1K A;  4BC7 A;  5AWV A;  5AE1 A;  3VTE A;  4PZF A;  2Y08 A;  3S1F A;  2BVF A;  1VDV A;  1DZN A;  1DII A;  4ZOH B;  4PWB A;  3LLB A;  3RJA A;  5AE2 A;  3LAE A;  5HMR A;  2P13 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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