1UXYA

Murb mutant with ser 229 replaced by ala, complex with enolpyruvyl-udp-n-acetylglucosamine
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
340
structure length
340
Chain Sequence
HSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDSVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGAFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKGMQIGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGEVSAVETIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords URIDINE DIPHOSPHO-N-ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE
total genus 107
structure length 340
sequence length 340
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 1996-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1uxyA02
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1uxyA03
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 1uxyA01
3PM9A 1W1KA 3W8ZA 1QLTA 3AMZA 2GQTA 1JRPA 3EUB3 1AHUA 2OAIA 2PLSA 2Q4WA 3S1CA 5AE2A 1FFVC 5AE1A 4PWBA 3TSJA 5HMRA 5HQXA 2VFVA 1N63C 1MBTA 2RK5A 1N5WC 4BBYA 1T3QC 3NVVB 3DQ0A 3FW9A 4PWCA 1ZXIC 1N5XA 1DIQA 2E3TA 1E8GA 1W1MA 2BVFA 3D2JA 3VTEA 1N60C 3C0PA 2O3GA 4PVEA 1W1JA 3B9JB 1FFUC 4PVJA 5AE3A 2VFSA 1FO4A 2PLIA 1RM6B 2AXRA 3NVZB 3HRDC 3D2HA 2W55A 2GQUA 5FXFA 2QKNA 2QPMA 4PVHA 2R8DA 3W8XA 1DIIA 3LLBA 2NQWA 2BVGA 2YVSA 1W1SA 2EXRA 3S1FA 3TX1A 3I99A 3SR6B 3BW7A 3FW7A 5FXDA 1ZR6A 1MBBA 1N61C 2W3SA 2W3RA 1E8HA 2MBRA 1E8FA 5ADZA 3NRZB 5G5GB 1VDVA 1F0XA 5FXPA 2VFRA 4JB1A 4OALA 3S1DA 4ML8A 1N62C 2I0KA 5HHZA 1W1OA 2Q85A 3FW8A 5D79A 5FXEA 3NVYB 1V97A 4XLOA 3AM9A 3W8WA 1AHVA 1WVEA 1QLUA 4ZOHB 3ETRB 3D2DA 2VFUA 4EC3A 3NS1B 4BCAA 2VFTA 5G5HB 3FWAA 4BC7A 1E0YA 1JROA 1UXYA 3GSYA 3KJMA 1SB3B 1WVFA 4PZFA 2P4PA 1W1LA 1WYGA 2BVHA 3LAEA 4DNSA 2R2ZA 4UD8A 1I19A 3NVWB 3TSHA 4JAYA 2W54A 4PYTA 4O95A 1HSKA 3AN1A 3S1EA 1W1RA 4BC9A 2P13A 1FIQB 1VAOA 3JS8A 4PVKA 1W1QA 2VAOA 1AHZA 1DZNA 2P3HA 3DEDA 4HG0A 4MLAA
chains in the Genus database with same CATH superfamily
3PM9A 1W1KA 3W8ZA 1QLTA 3AMZA 2GQTA 1JRPA 3EUB3 1AHUA 2OAIA 2PLSA 2Q4WA 3S1CA 5AE2A 1FFVC 5AE1A 4PWBA 3EJDB 3TSJA 5HMRA 5HQXA 2VFVA 1N63C 5I1VA 1MBTA 2RK5A 1N5WC 5K8EA 4BBYA 1T3QC 3POPA 3NVVB 3DQ0A 3FW9A 4PWCA 1ZXIC 1N5XA 1DIQA 2E3TA 2UUVA 1E8GA 1W1MA 2BVFA 3D2JA 3VTEA 1N60C 3C0PA 2O3GA 4PVEA 1W1JA 3B9JB 1FFUC 4PVJA 5AE3A 2VFSA 1FO4A 2PLIA 1RM6B 2AXRA 3NVZB 3HRDC 3D2HA 2W55A 2GQUA 5FXFA 2QKNA 2QPMA 4PVHA 2R8DA 3W8XA 1DIIA 3LLBA 2NQWA 3PQBA 2BVGA 2YVSA 1W1SA 2EXRA 3S1FA 2Y3SA 3TX1A 3I99A 3SR6B 3BW7A 2Y08A 3FW7A 5FXDA 1ZR6A 1MBBA 1N61C 3RJ8A 2W3SA 2W3RA 1E8HA 2MBRA 1E8FA 5ADZA 3NRZB 5G5GB 1VDVA 2Y3RA 1F0XA 5FXPA 2VFRA 4JB1A 3EJBB 4OALA 3S1DA 4ML8A 1N62C 2I0KA 2WDWA 5HHZA 1W1OA 2Q85A 3FW8A 5D79A 5FXEA 3NVYB 1V97A 5AWVA 3RJAA 4XLOA 3AM9A 3W8WA 1AHVA 1WVEA 1QLUA 4ZOHB 3ETRB 5L6GA 3D2DA 2VFUA 4EC3A 3NS1B 4BCAA 2VFTA 5G5HB 3FWAA 4BC7A 1E0YA 2IPIA 1JROA 1UXYA 3GSYA 3KJMA 3HSUA 1SB3B 1WVFA 4PZFA 2P4PA 1W1LA 1WYGA 5L6FA 2BVHA 3LAEA 4DNSA 2R2ZA 4UD8A 1I19A 3NVWB 3TSHA 2Y4GA 5I1WA 4JAYA 2W54A 4PYTA 4O95A 1HSKA 3AN1A 3S1EA 1W1RA 4BC9A 2P13A 1FIQB 1VAOA 3EJEB 3JS8A 4PVKA 1W1QA 2UUUA 2VAOA 1AHZA 1DZNA 2P3HA 3DEDA 4HG0A 4MLAA
chains in the Genus database with same CATH topology
3PM9A 1W1KA 3W8ZA 1QLTA 3AMZA 2GQTA 1JRPA 3EUB3 1AHUA 2OAIA 2PLSA 2Q4WA 3S1CA 5AE2A 1FFVC 5AE1A 4PWBA 3TSJA 5HMRA 5HQXA 2VFVA 1N63C 5I1VA 1MBTA 2RK5A 1N5WC 5K8EA 4BBYA 1T3QC 3POPA 3NVVB 3DQ0A 3FW9A 4PWCA 1ZXIC 1N5XA 1DIQA 2E3TA 2UUVA 1E8GA 1W1MA 2BVFA 3D2JA 3VTEA 1N60C 3C0PA 2O3GA 4PVEA 1W1JA 3B9JB 1FFUC 4PVJA 5AE3A 2VFSA 1FO4A 2PLIA 1RM6B 2AXRA 3NVZB 3HRDC 3D2HA 2W55A 2GQUA 5FXFA 2QKNA 2QPMA 4PVHA 2R8DA 3W8XA 1DIIA 3LLBA 2NQWA 3PQBA 2BVGA 2YVSA 1W1SA 2EXRA 3S1FA 2Y3SA 3TX1A 3I99A 3SR6B 3BW7A 2Y08A 3FW7A 5FXDA 1ZR6A 1MBBA 1N61C 3RJ8A 2W3SA 2W3RA 1E8HA 2MBRA 1E8FA 5ADZA 3NRZB 5G5GB 1VDVA 2Y3RA 1F0XA 5FXPA 2VFRA 4JB1A 4OALA 3S1DA 4ML8A 1N62C 2I0KA 2WDWA 5HHZA 1W1OA 2Q85A 3FW8A 5D79A 5FXEA 3NVYB 1V97A 5AWVA 3RJAA 4XLOA 3AM9A 3W8WA 1AHVA 1WVEA 1QLUA 4ZOHB 3ETRB 5L6GA 3D2DA 2VFUA 4EC3A 3NS1B 4BCAA 2VFTA 5G5HB 3FWAA 4BC7A 1E0YA 2IPIA 1JROA 1UXYA 3GSYA 3KJMA 3HSUA 1SB3B 1WVFA 4PZFA 2P4PA 1W1LA 1WYGA 5L6FA 2BVHA 3LAEA 4DNSA 2R2ZA 4UD8A 1I19A 3NVWB 3TSHA 2Y4GA 5I1WA 4JAYA 2W54A 4PYTA 4O95A 1HSKA 3AN1A 3S1EA 1W1RA 4BC9A 2P13A 1FIQB 1VAOA 3JS8A 4PVKA 1W1QA 2UUUA 2VAOA 1AHZA 1DZNA 2P3HA 3DEDA 4HG0A 4MLAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PM9 A;  1W1K A;  3W8Z A;  1QLT A;  3AMZ A;  2GQT A;  1JRP A;  3EUB 3;  1AHU A;  2OAI A;  2PLS A;  2Q4W A;  3S1C A;  5AE2 A;  1FFV C;  5AE1 A;  4PWB A;  3TSJ A;  5HMR A;  5HQX A;  2VFV A;  1N63 C;  1MBT A;  2RK5 A;  1N5W C;  4BBY A;  1T3Q C;  3NVV B;  3DQ0 A;  3FW9 A;  4PWC A;  1ZXI C;  1N5X A;  1DIQ A;  2E3T A;  1E8G A;  1W1M A;  2BVF A;  3D2J A;  3VTE A;  1N60 C;  3C0P A;  2O3G A;  4PVE A;  1W1J A;  3B9J B;  1FFU C;  4PVJ A;  5AE3 A;  2VFS A;  1FO4 A;  2PLI A;  1RM6 B;  2AXR A;  3NVZ B;  3HRD C;  3D2H A;  2W55 A;  2GQU A;  5FXF A;  2QKN A;  2QPM A;  4PVH A;  2R8D A;  3W8X A;  1DII A;  3LLB A;  2NQW A;  2BVG A;  2YVS A;  1W1S A;  2EXR A;  3S1F A;  3TX1 A;  3I99 A;  3SR6 B;  3BW7 A;  3FW7 A;  5FXD A;  1ZR6 A;  1MBB A;  1N61 C;  2W3S A;  2W3R A;  1E8H A;  2MBR A;  1E8F A;  5ADZ A;  3NRZ B;  5G5G B;  1VDV A;  1F0X A;  5FXP A;  2VFR A;  4JB1 A;  4OAL A;  3S1D A;  4ML8 A;  1N62 C;  2I0K A;  5HHZ A;  1W1O A;  2Q85 A;  3FW8 A;  5D79 A;  5FXE A;  3NVY B;  1V97 A;  4XLO A;  3AM9 A;  3W8W A;  1AHV A;  1WVE A;  1QLU A;  4ZOH B;  3ETR B;  3D2D A;  2VFU A;  4EC3 A;  3NS1 B;  4BCA A;  2VFT A;  5G5H B;  3FWA A;  4BC7 A;  1E0Y A;  1JRO A;  1UXY A;  3GSY A;  3KJM A;  1SB3 B;  1WVF A;  4PZF A;  2P4P A;  1W1L A;  1WYG A;  2BVH A;  3LAE A;  4DNS A;  2R2Z A;  4UD8 A;  1I19 A;  3NVW B;  3TSH A;  4JAY A;  2W54 A;  4PYT A;  4O95 A;  1HSK A;  3AN1 A;  3S1E A;  1W1R A;  4BC9 A;  2P13 A;  1FIQ B;  1VAO A;  3JS8 A;  4PVK A;  1W1Q A;  2VAO A;  1AHZ A;  1DZN A;  2P3H A;  3DED A;  4HG0 A;  4MLA A; 
#chains in the Genus database with same CATH topology
 3PM9 A;  1W1K A;  3W8Z A;  1QLT A;  3AMZ A;  2GQT A;  1JRP A;  3EUB 3;  1AHU A;  2OAI A;  2PLS A;  2Q4W A;  3S1C A;  5AE2 A;  1FFV C;  5AE1 A;  4PWB A;  3EJD B;  3TSJ A;  5HMR A;  5HQX A;  2VFV A;  1N63 C;  5I1V A;  1MBT A;  2RK5 A;  1N5W C;  5K8E A;  4BBY A;  1T3Q C;  3POP A;  3NVV B;  3DQ0 A;  3FW9 A;  4PWC A;  1ZXI C;  1N5X A;  1DIQ A;  2E3T A;  2UUV A;  1E8G A;  1W1M A;  2BVF A;  3D2J A;  3VTE A;  1N60 C;  3C0P A;  2O3G A;  4PVE A;  1W1J A;  3B9J B;  1FFU C;  4PVJ A;  5AE3 A;  2VFS A;  1FO4 A;  2PLI A;  1RM6 B;  2AXR A;  3NVZ B;  3HRD C;  3D2H A;  2W55 A;  2GQU A;  5FXF A;  2QKN A;  2QPM A;  4PVH A;  2R8D A;  3W8X A;  1DII A;  3LLB A;  2NQW A;  3PQB A;  2BVG A;  2YVS A;  1W1S A;  2EXR A;  3S1F A;  2Y3S A;  3TX1 A;  3I99 A;  3SR6 B;  3BW7 A;  2Y08 A;  3FW7 A;  5FXD A;  1ZR6 A;  1MBB A;  1N61 C;  3RJ8 A;  2W3S A;  2W3R A;  1E8H A;  2MBR A;  1E8F A;  5ADZ A;  3NRZ B;  5G5G B;  1VDV A;  2Y3R A;  1F0X A;  5FXP A;  2VFR A;  4JB1 A;  3EJB B;  4OAL A;  3S1D A;  4ML8 A;  1N62 C;  2I0K A;  2WDW A;  5HHZ A;  1W1O A;  2Q85 A;  3FW8 A;  5D79 A;  5FXE A;  3NVY B;  1V97 A;  5AWV A;  3RJA A;  4XLO A;  3AM9 A;  3W8W A;  1AHV A;  1WVE A;  1QLU A;  4ZOH B;  3ETR B;  5L6G A;  3D2D A;  2VFU A;  4EC3 A;  3NS1 B;  4BCA A;  2VFT A;  5G5H B;  3FWA A;  4BC7 A;  1E0Y A;  2IPI A;  1JRO A;  1UXY A;  3GSY A;  3KJM A;  3HSU A;  1SB3 B;  1WVF A;  4PZF A;  2P4P A;  1W1L A;  1WYG A;  5L6F A;  2BVH A;  3LAE A;  4DNS A;  2R2Z A;  4UD8 A;  1I19 A;  3NVW B;  3TSH A;  2Y4G A;  5I1W A;  4JAY A;  2W54 A;  4PYT A;  4O95 A;  1HSK A;  3AN1 A;  3S1E A;  1W1R A;  4BC9 A;  2P13 A;  1FIQ B;  1VAO A;  3EJE B;  3JS8 A;  4PVK A;  1W1Q A;  2UUU A;  2VAO A;  1AHZ A;  1DZN A;  2P3H A;  3DED A;  4HG0 A;  4MLA A; 
#chains in the Genus database with same CATH homology
 3PM9 A;  1W1K A;  3W8Z A;  1QLT A;  3AMZ A;  2GQT A;  1JRP A;  3EUB 3;  1AHU A;  2OAI A;  2PLS A;  2Q4W A;  3S1C A;  5AE2 A;  1FFV C;  5AE1 A;  4PWB A;  3TSJ A;  5HMR A;  5HQX A;  2VFV A;  1N63 C;  5I1V A;  1MBT A;  2RK5 A;  1N5W C;  5K8E A;  4BBY A;  1T3Q C;  3POP A;  3NVV B;  3DQ0 A;  3FW9 A;  4PWC A;  1ZXI C;  1N5X A;  1DIQ A;  2E3T A;  2UUV A;  1E8G A;  1W1M A;  2BVF A;  3D2J A;  3VTE A;  1N60 C;  3C0P A;  2O3G A;  4PVE A;  1W1J A;  3B9J B;  1FFU C;  4PVJ A;  5AE3 A;  2VFS A;  1FO4 A;  2PLI A;  1RM6 B;  2AXR A;  3NVZ B;  3HRD C;  3D2H A;  2W55 A;  2GQU A;  5FXF A;  2QKN A;  2QPM A;  4PVH A;  2R8D A;  3W8X A;  1DII A;  3LLB A;  2NQW A;  3PQB A;  2BVG A;  2YVS A;  1W1S A;  2EXR A;  3S1F A;  2Y3S A;  3TX1 A;  3I99 A;  3SR6 B;  3BW7 A;  2Y08 A;  3FW7 A;  5FXD A;  1ZR6 A;  1MBB A;  1N61 C;  3RJ8 A;  2W3S A;  2W3R A;  1E8H A;  2MBR A;  1E8F A;  5ADZ A;  3NRZ B;  5G5G B;  1VDV A;  2Y3R A;  1F0X A;  5FXP A;  2VFR A;  4JB1 A;  4OAL A;  3S1D A;  4ML8 A;  1N62 C;  2I0K A;  2WDW A;  5HHZ A;  1W1O A;  2Q85 A;  3FW8 A;  5D79 A;  5FXE A;  3NVY B;  1V97 A;  5AWV A;  3RJA A;  4XLO A;  3AM9 A;  3W8W A;  1AHV A;  1WVE A;  1QLU A;  4ZOH B;  3ETR B;  5L6G A;  3D2D A;  2VFU A;  4EC3 A;  3NS1 B;  4BCA A;  2VFT A;  5G5H B;  3FWA A;  4BC7 A;  1E0Y A;  2IPI A;  1JRO A;  1UXY A;  3GSY A;  3KJM A;  3HSU A;  1SB3 B;  1WVF A;  4PZF A;  2P4P A;  1W1L A;  1WYG A;  5L6F A;  2BVH A;  3LAE A;  4DNS A;  2R2Z A;  4UD8 A;  1I19 A;  3NVW B;  3TSH A;  2Y4G A;  5I1W A;  4JAY A;  2W54 A;  4PYT A;  4O95 A;  1HSK A;  3AN1 A;  3S1E A;  1W1R A;  4BC9 A;  2P13 A;  1FIQ B;  1VAO A;  3JS8 A;  4PVK A;  1W1Q A;  2UUU A;  2VAO A;  1AHZ A;  1DZN A;  2P3H A;  3DED A;  4HG0 A;  4MLA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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