1W1LA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: phe454tyr mutant
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDYIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGEYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Penicillium simplicissimum
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 170
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1lA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1lA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1lA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1lA03
3FW8A 3D2JA 2W3SA 3S1FA 3NS1B 1AHZA 4ML8A 1FO4A 4PWCA 2Q4WA 5ADZA 1JROA 1ZXIC 4OALA 5AE3A 4PVEA 1W1QA 5D79A 3FW7A 3LAEA 4BCAA 3AM9A 4EC3A 3B9JB 4PWBA 1N61C 4JAYA 4ZOHB 2O3GA 1E8HA 2VFVA 1DIIA 1AHUA 1SB3B 1WVFA 2I0KA 3AMZA 1W1KA 3TSHA 2YVSA 1WVEA 1FFVC 4BC7A 2NQWA 3W8ZA 3NVVB 4MLAA 2BVFA 1DZNA 3C0PA 3W8WA 3EUB3 3DQ0A 3D2DA 2EXRA 4UD8A 3TSJA 5FXFA 3S1DA 1T3QC 4PVKA 1I19A 4DNSA 2BVHA 3NVYB 2P13A 4O95A 2VFTA 1MBBA 5FXPA 3HRDC 1E8GA 1N62C 1V97A 2W54A 1JRPA 1E8FA 1W1LA 2VFRA 4PZFA 5G5HB 1QLTA 1ZR6A 5HMRA 1E0YA 4PYTA 3NVZB 5FXEA 4PVJA 4PVHA 1W1RA 1FIQB 2QPMA 2PLSA 1VAOA 3ETRB 3GSYA 5HQXA 4HG0A 3JS8A 1MBTA 1N5WC 4XLOA 3D2HA 5HHZA 3AN1A 3DEDA 3VTEA 5FXDA 1F0XA 2W55A 4JB1A 5AE1A 5G5GB 1QLUA 2P3HA 1AHVA 1FFUC 3I99A 3TX1A 4BBYA 3FW9A 2OAIA 1W1OA 1W1SA 2PLIA 3S1CA 3LLBA 3S1EA 2VFUA 1N60C 2P4PA 3NRZB 1VDVA 3NVWB 2R2ZA 2R8DA 5AE2A 3SR6B 2W3RA 3BW7A 3FWAA 1W1JA 2QKNA 1W1MA 3PM9A 2Q85A 1HSKA 1RM6B 2BVGA 2GQUA 2E3TA 1DIQA 3W8XA 2AXRA 2MBRA 1UXYA 2VFSA 2VAOA 1N63C 1N5XA 3KJMA 4BC9A 1WYGA 2RK5A 2GQTA
chains in the Genus database with same CATH superfamily
3FW8A 3D2JA 2W3SA 3EJBB 3S1FA 3NS1B 1AHZA 2Y4GA 4ML8A 1FO4A 4PWCA 2Q4WA 5ADZA 1JROA 1ZXIC 4OALA 5AE3A 4PVEA 1W1QA 5D79A 3FW7A 5I1WA 3POPA 3LAEA 4BCAA 3AM9A 4EC3A 5K8EA 3B9JB 4PWBA 1N61C 4JAYA 4ZOHB 2O3GA 2Y3RA 1E8HA 2Y08A 3EJDB 2VFVA 1DIIA 1AHUA 1SB3B 1WVFA 2I0KA 3AMZA 2WDWA 1W1KA 3TSHA 2YVSA 1WVEA 1FFVC 3PQBA 4BC7A 2NQWA 3W8ZA 3NVVB 4MLAA 2BVFA 1DZNA 3C0PA 3W8WA 3EUB3 3DQ0A 3D2DA 2EXRA 4UD8A 3TSJA 5FXFA 3S1DA 1T3QC 4PVKA 1I19A 4DNSA 5L6GA 2BVHA 5I1VA 3NVYB 2P13A 4O95A 2VFTA 1MBBA 5FXPA 3HRDC 1E8GA 1N62C 1V97A 2W54A 1JRPA 1E8FA 1W1LA 2UUUA 2VFRA 4PZFA 5G5HB 1QLTA 1ZR6A 5HMRA 1E0YA 2UUVA 3RJ8A 4PYTA 3NVZB 5FXEA 4PVJA 4PVHA 1W1RA 1FIQB 2QPMA 2PLSA 1VAOA 3ETRB 3GSYA 5HQXA 4HG0A 3JS8A 1MBTA 1N5WC 4XLOA 3D2HA 5HHZA 3AN1A 3DEDA 3VTEA 5FXDA 1F0XA 2W55A 4JB1A 5AE1A 5G5GB 1QLUA 2P3HA 1AHVA 1FFUC 3I99A 3TX1A 4BBYA 3HSUA 3FW9A 2IPIA 2OAIA 1W1OA 1W1SA 2PLIA 3S1CA 3LLBA 3S1EA 3EJEB 2VFUA 1N60C 2Y3SA 2P4PA 3NRZB 1VDVA 3NVWB 2R2ZA 2R8DA 5AE2A 3RJAA 3SR6B 2W3RA 3BW7A 3FWAA 5L6FA 1W1JA 2QKNA 1W1MA 3PM9A 2Q85A 1HSKA 1RM6B 2BVGA 2GQUA 2E3TA 1DIQA 3W8XA 2AXRA 2MBRA 1UXYA 2VFSA 2VAOA 1N63C 1N5XA 3KJMA 5AWVA 4BC9A 1WYGA 2RK5A 2GQTA
chains in the Genus database with same CATH topology
3FW8A 3D2JA 2W3SA 3S1FA 3NS1B 1AHZA 2Y4GA 4ML8A 1FO4A 4PWCA 2Q4WA 5ADZA 1JROA 1ZXIC 4OALA 5AE3A 4PVEA 1W1QA 5D79A 3FW7A 5I1WA 3POPA 3LAEA 4BCAA 3AM9A 4EC3A 5K8EA 3B9JB 4PWBA 1N61C 4JAYA 4ZOHB 2O3GA 2Y3RA 1E8HA 2Y08A 2VFVA 1DIIA 1AHUA 1SB3B 1WVFA 2I0KA 3AMZA 2WDWA 1W1KA 3TSHA 2YVSA 1WVEA 1FFVC 3PQBA 4BC7A 2NQWA 3W8ZA 3NVVB 4MLAA 2BVFA 1DZNA 3C0PA 3W8WA 3EUB3 3DQ0A 3D2DA 2EXRA 4UD8A 3TSJA 5FXFA 3S1DA 1T3QC 4PVKA 1I19A 4DNSA 5L6GA 2BVHA 5I1VA 3NVYB 2P13A 4O95A 2VFTA 1MBBA 5FXPA 3HRDC 1E8GA 1N62C 1V97A 2W54A 1JRPA 1E8FA 1W1LA 2UUUA 2VFRA 4PZFA 5G5HB 1QLTA 1ZR6A 5HMRA 1E0YA 2UUVA 3RJ8A 4PYTA 3NVZB 5FXEA 4PVJA 4PVHA 1W1RA 1FIQB 2QPMA 2PLSA 1VAOA 3ETRB 3GSYA 5HQXA 4HG0A 3JS8A 1MBTA 1N5WC 4XLOA 3D2HA 5HHZA 3AN1A 3DEDA 3VTEA 5FXDA 1F0XA 2W55A 4JB1A 5AE1A 5G5GB 1QLUA 2P3HA 1AHVA 1FFUC 3I99A 3TX1A 4BBYA 3HSUA 3FW9A 2IPIA 2OAIA 1W1OA 1W1SA 2PLIA 3S1CA 3LLBA 3S1EA 2VFUA 1N60C 2Y3SA 2P4PA 3NRZB 1VDVA 3NVWB 2R2ZA 2R8DA 5AE2A 3RJAA 3SR6B 2W3RA 3BW7A 3FWAA 5L6FA 1W1JA 2QKNA 1W1MA 3PM9A 2Q85A 1HSKA 1RM6B 2BVGA 2GQUA 2E3TA 1DIQA 3W8XA 2AXRA 2MBRA 1UXYA 2VFSA 2VAOA 1N63C 1N5XA 3KJMA 5AWVA 4BC9A 1WYGA 2RK5A 2GQTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FW8 A;  3D2J A;  2W3S A;  3S1F A;  3NS1 B;  1AHZ A;  4ML8 A;  1FO4 A;  4PWC A;  2Q4W A;  5ADZ A;  1JRO A;  1ZXI C;  4OAL A;  5AE3 A;  4PVE A;  1W1Q A;  5D79 A;  3FW7 A;  3LAE A;  4BCA A;  3AM9 A;  4EC3 A;  3B9J B;  4PWB A;  1N61 C;  4JAY A;  4ZOH B;  2O3G A;  1E8H A;  2VFV A;  1DII A;  1AHU A;  1SB3 B;  1WVF A;  2I0K A;  3AMZ A;  1W1K A;  3TSH A;  2YVS A;  1WVE A;  1FFV C;  4BC7 A;  2NQW A;  3W8Z A;  3NVV B;  4MLA A;  2BVF A;  1DZN A;  3C0P A;  3W8W A;  3EUB 3;  3DQ0 A;  3D2D A;  2EXR A;  4UD8 A;  3TSJ A;  5FXF A;  3S1D A;  1T3Q C;  4PVK A;  1I19 A;  4DNS A;  2BVH A;  3NVY B;  2P13 A;  4O95 A;  2VFT A;  1MBB A;  5FXP A;  3HRD C;  1E8G A;  1N62 C;  1V97 A;  2W54 A;  1JRP A;  1E8F A;  1W1L A;  2VFR A;  4PZF A;  5G5H B;  1QLT A;  1ZR6 A;  5HMR A;  1E0Y A;  4PYT A;  3NVZ B;  5FXE A;  4PVJ A;  4PVH A;  1W1R A;  1FIQ B;  2QPM A;  2PLS A;  1VAO A;  3ETR B;  3GSY A;  5HQX A;  4HG0 A;  3JS8 A;  1MBT A;  1N5W C;  4XLO A;  3D2H A;  5HHZ A;  3AN1 A;  3DED A;  3VTE A;  5FXD A;  1F0X A;  2W55 A;  4JB1 A;  5AE1 A;  5G5G B;  1QLU A;  2P3H A;  1AHV A;  1FFU C;  3I99 A;  3TX1 A;  4BBY A;  3FW9 A;  2OAI A;  1W1O A;  1W1S A;  2PLI A;  3S1C A;  3LLB A;  3S1E A;  2VFU A;  1N60 C;  2P4P A;  3NRZ B;  1VDV A;  3NVW B;  2R2Z A;  2R8D A;  5AE2 A;  3SR6 B;  2W3R A;  3BW7 A;  3FWA A;  1W1J A;  2QKN A;  1W1M A;  3PM9 A;  2Q85 A;  1HSK A;  1RM6 B;  2BVG A;  2GQU A;  2E3T A;  1DIQ A;  3W8X A;  2AXR A;  2MBR A;  1UXY A;  2VFS A;  2VAO A;  1N63 C;  1N5X A;  3KJM A;  4BC9 A;  1WYG A;  2RK5 A;  2GQT A; 
#chains in the Genus database with same CATH topology
 3FW8 A;  3D2J A;  2W3S A;  3EJB B;  3S1F A;  3NS1 B;  1AHZ A;  2Y4G A;  4ML8 A;  1FO4 A;  4PWC A;  2Q4W A;  5ADZ A;  1JRO A;  1ZXI C;  4OAL A;  5AE3 A;  4PVE A;  1W1Q A;  5D79 A;  3FW7 A;  5I1W A;  3POP A;  3LAE A;  4BCA A;  3AM9 A;  4EC3 A;  5K8E A;  3B9J B;  4PWB A;  1N61 C;  4JAY A;  4ZOH B;  2O3G A;  2Y3R A;  1E8H A;  2Y08 A;  3EJD B;  2VFV A;  1DII A;  1AHU A;  1SB3 B;  1WVF A;  2I0K A;  3AMZ A;  2WDW A;  1W1K A;  3TSH A;  2YVS A;  1WVE A;  1FFV C;  3PQB A;  4BC7 A;  2NQW A;  3W8Z A;  3NVV B;  4MLA A;  2BVF A;  1DZN A;  3C0P A;  3W8W A;  3EUB 3;  3DQ0 A;  3D2D A;  2EXR A;  4UD8 A;  3TSJ A;  5FXF A;  3S1D A;  1T3Q C;  4PVK A;  1I19 A;  4DNS A;  5L6G A;  2BVH A;  5I1V A;  3NVY B;  2P13 A;  4O95 A;  2VFT A;  1MBB A;  5FXP A;  3HRD C;  1E8G A;  1N62 C;  1V97 A;  2W54 A;  1JRP A;  1E8F A;  1W1L A;  2UUU A;  2VFR A;  4PZF A;  5G5H B;  1QLT A;  1ZR6 A;  5HMR A;  1E0Y A;  2UUV A;  3RJ8 A;  4PYT A;  3NVZ B;  5FXE A;  4PVJ A;  4PVH A;  1W1R A;  1FIQ B;  2QPM A;  2PLS A;  1VAO A;  3ETR B;  3GSY A;  5HQX A;  4HG0 A;  3JS8 A;  1MBT A;  1N5W C;  4XLO A;  3D2H A;  5HHZ A;  3AN1 A;  3DED A;  3VTE A;  5FXD A;  1F0X A;  2W55 A;  4JB1 A;  5AE1 A;  5G5G B;  1QLU A;  2P3H A;  1AHV A;  1FFU C;  3I99 A;  3TX1 A;  4BBY A;  3HSU A;  3FW9 A;  2IPI A;  2OAI A;  1W1O A;  1W1S A;  2PLI A;  3S1C A;  3LLB A;  3S1E A;  3EJE B;  2VFU A;  1N60 C;  2Y3S A;  2P4P A;  3NRZ B;  1VDV A;  3NVW B;  2R2Z A;  2R8D A;  5AE2 A;  3RJA A;  3SR6 B;  2W3R A;  3BW7 A;  3FWA A;  5L6F A;  1W1J A;  2QKN A;  1W1M A;  3PM9 A;  2Q85 A;  1HSK A;  1RM6 B;  2BVG A;  2GQU A;  2E3T A;  1DIQ A;  3W8X A;  2AXR A;  2MBR A;  1UXY A;  2VFS A;  2VAO A;  1N63 C;  1N5X A;  3KJM A;  5AWV A;  4BC9 A;  1WYG A;  2RK5 A;  2GQT A; 
#chains in the Genus database with same CATH homology
 3FW8 A;  3D2J A;  2W3S A;  3S1F A;  3NS1 B;  1AHZ A;  2Y4G A;  4ML8 A;  1FO4 A;  4PWC A;  2Q4W A;  5ADZ A;  1JRO A;  1ZXI C;  4OAL A;  5AE3 A;  4PVE A;  1W1Q A;  5D79 A;  3FW7 A;  5I1W A;  3POP A;  3LAE A;  4BCA A;  3AM9 A;  4EC3 A;  5K8E A;  3B9J B;  4PWB A;  1N61 C;  4JAY A;  4ZOH B;  2O3G A;  2Y3R A;  1E8H A;  2Y08 A;  2VFV A;  1DII A;  1AHU A;  1SB3 B;  1WVF A;  2I0K A;  3AMZ A;  2WDW A;  1W1K A;  3TSH A;  2YVS A;  1WVE A;  1FFV C;  3PQB A;  4BC7 A;  2NQW A;  3W8Z A;  3NVV B;  4MLA A;  2BVF A;  1DZN A;  3C0P A;  3W8W A;  3EUB 3;  3DQ0 A;  3D2D A;  2EXR A;  4UD8 A;  3TSJ A;  5FXF A;  3S1D A;  1T3Q C;  4PVK A;  1I19 A;  4DNS A;  5L6G A;  2BVH A;  5I1V A;  3NVY B;  2P13 A;  4O95 A;  2VFT A;  1MBB A;  5FXP A;  3HRD C;  1E8G A;  1N62 C;  1V97 A;  2W54 A;  1JRP A;  1E8F A;  1W1L A;  2UUU A;  2VFR A;  4PZF A;  5G5H B;  1QLT A;  1ZR6 A;  5HMR A;  1E0Y A;  2UUV A;  3RJ8 A;  4PYT A;  3NVZ B;  5FXE A;  4PVJ A;  4PVH A;  1W1R A;  1FIQ B;  2QPM A;  2PLS A;  1VAO A;  3ETR B;  3GSY A;  5HQX A;  4HG0 A;  3JS8 A;  1MBT A;  1N5W C;  4XLO A;  3D2H A;  5HHZ A;  3AN1 A;  3DED A;  3VTE A;  5FXD A;  1F0X A;  2W55 A;  4JB1 A;  5AE1 A;  5G5G B;  1QLU A;  2P3H A;  1AHV A;  1FFU C;  3I99 A;  3TX1 A;  4BBY A;  3HSU A;  3FW9 A;  2IPI A;  2OAI A;  1W1O A;  1W1S A;  2PLI A;  3S1C A;  3LLB A;  3S1E A;  2VFU A;  1N60 C;  2Y3S A;  2P4P A;  3NRZ B;  1VDV A;  3NVW B;  2R2Z A;  2R8D A;  5AE2 A;  3RJA A;  3SR6 B;  2W3R A;  3BW7 A;  3FWA A;  5L6F A;  1W1J A;  2QKN A;  1W1M A;  3PM9 A;  2Q85 A;  1HSK A;  1RM6 B;  2BVG A;  2GQU A;  2E3T A;  1DIQ A;  3W8X A;  2AXR A;  2MBR A;  1UXY A;  2VFS A;  2VAO A;  1N63 C;  1N5X A;  3KJM A;  5AWV A;  4BC9 A;  1WYG A;  2RK5 A;  2GQT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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