1W1MA

Structure of the octameric flavoenzyme vanillyl-alcohol oxidase: glu502gly mutant
Total Genus 172
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
172
sequence length
555
structure length
550
Chain Sequence
EFRPLTLPPKLSLSDFNEFIQDIIRIVGSENVEVISVDGSYMKPTHTHDPHHVMDQDYFLASAIVAPRNVADVQSIVGLANKFSFPLWPISIGRNSGYGGAAPRVSGSVVLDMGKNMNRVLEVNVEGAYCVVEPGVTYHDLHNYLEANNLRDKLWLDVPDLGGGSVLGNAVERGVGYTPYGDHWMMHSGMEVVLANGELLRTGMGALPDPKRPETMGLKPEDQPWSKIAHLFPYGFGPYIDGLFSQSNMGIVTKIGIWLMPNPRGYQSYLITLPKDGDLKQAVDIIRPLRLGMALQNVPTIRHILLDAAVLGDKRSYSSRTEPLSDEELDKIAKQLNLGRWNFYGALYGPEPIRRVLWETIKDAFSAIPGVKFYFPEDTPENSVLRVRDKTMQGIPTYDELKWIDWLPNGAHLFFSPIAKVSGEDAMMQYAVTKKRCQEAGLDFIGTFTVGMREMHHIVCIVFNKKDLIQKRKVQWLMRTLIDDCAANGWGGYRTHLAFMDQIMETYNWNNSSFLRFNEVLKNAVDPNGIIAPGKSGVWPSQYSHVTWKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Laboratory-Evolved Vanillyl-Alcohol Oxidase Produces Natural Vanillin
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Penicillium simplicissimum
molecule keywords VANILLYL-ALCOHOL OXIDASE
total genus 172
structure length 550
sequence length 555
chains with identical sequence B
ec nomenclature ec 1.1.3.38: Vanillyl-alcohol oxidase.
pdb deposition date 2004-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02913 FAD-oxidase_C FAD linked oxidases, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.45.10 Mainly Alpha Orthogonal Bundle Vanillyl-alcohol Oxidase; Chain A, domain 4 Vanillyl-alcohol Oxidase; Chain A, domain 4 1w1mA04
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 1w1mA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 1w1mA02
3.40.462.10 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 FAD-linked oxidases, C-terminal domain 1w1mA03
3GSYA 1W1SA 2BVGA 3S1CA 3NVYB 3FWAA 4JB1A 2EXRA 3I99A 3W8XA 1W1KA 1WVFA 3TSHA 3FW9A 2BVHA 2VFSA 3AM9A 1QLUA 5FXFA 2MBRA 2E3TA 4EC3A 5AE1A 3D2JA 2R2ZA 4PVJA 2P4PA 1WYGA 3BW7A 5D79A 1AHVA 3NVWB 3S1FA 2VAOA 1W1LA 3HRDC 5AE2A 5HMRA 2NQWA 2GQTA 3VTEA 4BCAA 3PM9A 2GQUA 2Q4WA 4PVKA 4MLAA 2AXRA 2VFVA 5G5GB 1V97A 3NRZB 3AMZA 4OALA 3D2DA 3DQ0A 1FFVC 1N5WC 1W1JA 2VFUA 2QKNA 1FIQB 1N62C 1DIQA 3B9JB 1W1OA 4JAYA 3S1DA 2VFTA 1ZR6A 3W8ZA 3FW8A 2YVSA 1N5XA 5FXPA 2I0KA 2PLIA 4PVEA 4BC9A 4ML8A 3LLBA 1JRPA 1AHUA 3TSJA 2Q85A 1JROA 1FFUC 1W1QA 4PWBA 3NVVB 4XLOA 4UD8A 1SB3B 3KJMA 1E8HA 1DZNA 5HHZA 2QPMA 2W3RA 4BBYA 1UXYA 4O95A 1N61C 1MBTA 1T3QC 5ADZA 2R8DA 2W54A 4PWCA 1QLTA 2PLSA 3NS1B 4PVHA 1W1MA 3FW7A 4DNSA 1N60C 4PZFA 3C0PA 1MBBA 2OAIA 2O3GA 2W3SA 2P13A 3LAEA 1E8GA 5G5HB 4HG0A 2W55A 5HQXA 2VFRA 3TX1A 1N63C 3W8WA 1HSKA 1I19A 3NVZB 4BC7A 1VAOA 1WVEA 1E8FA 2RK5A 3S1EA 3EUB3 3ETRB 3JS8A 5FXDA 4ZOHB 1RM6B 4PYTA 2BVFA 1E0YA 3DEDA 3SR6B 1W1RA 1VDVA 1ZXIC 3AN1A 3D2HA 1DIIA 1F0XA 5FXEA 1AHZA 1FO4A 2P3HA 5AE3A
chains in the Genus database with same CATH superfamily
3GSYA 1W1SA 2BVGA 3NVYB 3S1CA 2Y08A 3FWAA 4JB1A 3PQBA 2EXRA 3I99A 3W8XA 1W1KA 1WVFA 3TSHA 3FW9A 2BVHA 2VFSA 3AM9A 3EJBB 1QLUA 5FXFA 2MBRA 2E3TA 4EC3A 5AE1A 3D2JA 2R2ZA 4PVJA 2P4PA 1WYGA 3BW7A 5D79A 2WDWA 2Y3SA 1AHVA 3NVWB 3S1FA 2VAOA 1W1LA 3HRDC 5AE2A 5HMRA 2NQWA 2GQTA 3VTEA 4BCAA 5L6GA 2IPIA 2UUVA 3PM9A 2GQUA 2Q4WA 4PVKA 4MLAA 2AXRA 2VFVA 5G5GB 1V97A 3NRZB 3AMZA 4OALA 3D2DA 3DQ0A 1FFVC 1N5WC 1W1JA 2VFUA 2QKNA 1FIQB 1N62C 1DIQA 3B9JB 1W1OA 4JAYA 3S1DA 2VFTA 1ZR6A 3W8ZA 3FW8A 2UUUA 1N5XA 2YVSA 5FXPA 2I0KA 2PLIA 4PVEA 4BC9A 4ML8A 3LLBA 1JRPA 1AHUA 3TSJA 2Q85A 1JROA 5AWVA 1FFUC 1W1QA 4PWBA 3NVVB 4XLOA 4UD8A 1SB3B 3HSUA 3RJ8A 3KJMA 1E8HA 1DZNA 5HHZA 5K8EA 2QPMA 2W3RA 4BBYA 1UXYA 4O95A 1N61C 1MBTA 1T3QC 5ADZA 2R8DA 2W54A 5I1WA 4PWCA 1QLTA 2PLSA 3NS1B 2Y4GA 4PVHA 1W1MA 3FW7A 4DNSA 1N60C 4PZFA 3C0PA 1MBBA 3EJDB 2OAIA 3RJAA 5L6FA 2O3GA 2W3SA 2P13A 3LAEA 1E8GA 2Y3RA 5G5HB 4HG0A 5I1VA 2W55A 5HQXA 2VFRA 3TX1A 1N63C 3W8WA 1HSKA 1I19A 3NVZB 4BC7A 3EJEB 1VAOA 1WVEA 1E8FA 2RK5A 3S1EA 3EUB3 3ETRB 3JS8A 5FXDA 4ZOHB 1RM6B 4PYTA 2BVFA 1E0YA 3DEDA 3SR6B 1W1RA 3POPA 1VDVA 1ZXIC 3AN1A 3D2HA 1DIIA 1F0XA 5FXEA 1AHZA 1FO4A 2P3HA 5AE3A
chains in the Genus database with same CATH topology
3GSYA 1W1SA 2BVGA 3S1CA 3NVYB 2Y08A 3FWAA 4JB1A 3PQBA 2EXRA 3I99A 3W8XA 1W1KA 1WVFA 3TSHA 3FW9A 2BVHA 2VFSA 3AM9A 1QLUA 5FXFA 2MBRA 2E3TA 4EC3A 5AE1A 3D2JA 2R2ZA 4PVJA 2P4PA 1WYGA 3BW7A 5D79A 2WDWA 2Y3SA 1AHVA 3NVWB 3S1FA 2VAOA 1W1LA 3HRDC 5AE2A 5HMRA 2NQWA 2GQTA 3VTEA 4BCAA 5L6GA 2IPIA 2UUVA 3PM9A 2GQUA 2Q4WA 4PVKA 4MLAA 2AXRA 2VFVA 5G5GB 1V97A 3NRZB 3AMZA 4OALA 3D2DA 3DQ0A 1FFVC 1N5WC 1W1JA 2VFUA 2QKNA 1FIQB 1N62C 1DIQA 3B9JB 1W1OA 4JAYA 3S1DA 2VFTA 1ZR6A 3W8ZA 3FW8A 2UUUA 1N5XA 2YVSA 5FXPA 2I0KA 2PLIA 4PVEA 4BC9A 4ML8A 3LLBA 1JRPA 1AHUA 3TSJA 2Q85A 1JROA 5AWVA 1FFUC 1W1QA 4PWBA 3NVVB 4XLOA 4UD8A 1SB3B 3HSUA 3RJ8A 3KJMA 1E8HA 1DZNA 5HHZA 5K8EA 2QPMA 2W3RA 4BBYA 1UXYA 4O95A 1N61C 1MBTA 1T3QC 5ADZA 2R8DA 2W54A 5I1WA 4PWCA 1QLTA 2PLSA 3NS1B 2Y4GA 4PVHA 1W1MA 3FW7A 4DNSA 1N60C 4PZFA 3C0PA 1MBBA 3RJAA 2OAIA 5L6FA 2O3GA 2W3SA 2P13A 3LAEA 1E8GA 2Y3RA 5G5HB 4HG0A 5I1VA 2W55A 5HQXA 2VFRA 3TX1A 1N63C 3W8WA 1HSKA 1I19A 3NVZB 4BC7A 1VAOA 1WVEA 1E8FA 2RK5A 3S1EA 3EUB3 3ETRB 3JS8A 5FXDA 4ZOHB 1RM6B 4PYTA 2BVFA 1E0YA 3DEDA 3SR6B 1W1RA 3POPA 1VDVA 1ZXIC 3AN1A 3D2HA 1DIIA 1F0XA 5FXEA 1AHZA 1FO4A 2P3HA 5AE3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GSY A;  1W1S A;  2BVG A;  3S1C A;  3NVY B;  3FWA A;  4JB1 A;  2EXR A;  3I99 A;  3W8X A;  1W1K A;  1WVF A;  3TSH A;  3FW9 A;  2BVH A;  2VFS A;  3AM9 A;  1QLU A;  5FXF A;  2MBR A;  2E3T A;  4EC3 A;  5AE1 A;  3D2J A;  2R2Z A;  4PVJ A;  2P4P A;  1WYG A;  3BW7 A;  5D79 A;  1AHV A;  3NVW B;  3S1F A;  2VAO A;  1W1L A;  3HRD C;  5AE2 A;  5HMR A;  2NQW A;  2GQT A;  3VTE A;  4BCA A;  3PM9 A;  2GQU A;  2Q4W A;  4PVK A;  4MLA A;  2AXR A;  2VFV A;  5G5G B;  1V97 A;  3NRZ B;  3AMZ A;  4OAL A;  3D2D A;  3DQ0 A;  1FFV C;  1N5W C;  1W1J A;  2VFU A;  2QKN A;  1FIQ B;  1N62 C;  1DIQ A;  3B9J B;  1W1O A;  4JAY A;  3S1D A;  2VFT A;  1ZR6 A;  3W8Z A;  3FW8 A;  2YVS A;  1N5X A;  5FXP A;  2I0K A;  2PLI A;  4PVE A;  4BC9 A;  4ML8 A;  3LLB A;  1JRP A;  1AHU A;  3TSJ A;  2Q85 A;  1JRO A;  1FFU C;  1W1Q A;  4PWB A;  3NVV B;  4XLO A;  4UD8 A;  1SB3 B;  3KJM A;  1E8H A;  1DZN A;  5HHZ A;  2QPM A;  2W3R A;  4BBY A;  1UXY A;  4O95 A;  1N61 C;  1MBT A;  1T3Q C;  5ADZ A;  2R8D A;  2W54 A;  4PWC A;  1QLT A;  2PLS A;  3NS1 B;  4PVH A;  1W1M A;  3FW7 A;  4DNS A;  1N60 C;  4PZF A;  3C0P A;  1MBB A;  2OAI A;  2O3G A;  2W3S A;  2P13 A;  3LAE A;  1E8G A;  5G5H B;  4HG0 A;  2W55 A;  5HQX A;  2VFR A;  3TX1 A;  1N63 C;  3W8W A;  1HSK A;  1I19 A;  3NVZ B;  4BC7 A;  1VAO A;  1WVE A;  1E8F A;  2RK5 A;  3S1E A;  3EUB 3;  3ETR B;  3JS8 A;  5FXD A;  4ZOH B;  1RM6 B;  4PYT A;  2BVF A;  1E0Y A;  3DED A;  3SR6 B;  1W1R A;  1VDV A;  1ZXI C;  3AN1 A;  3D2H A;  1DII A;  1F0X A;  5FXE A;  1AHZ A;  1FO4 A;  2P3H A;  5AE3 A; 
#chains in the Genus database with same CATH topology
 3GSY A;  1W1S A;  2BVG A;  3NVY B;  3S1C A;  2Y08 A;  3FWA A;  4JB1 A;  3PQB A;  2EXR A;  3I99 A;  3W8X A;  1W1K A;  1WVF A;  3TSH A;  3FW9 A;  2BVH A;  2VFS A;  3AM9 A;  3EJB B;  1QLU A;  5FXF A;  2MBR A;  2E3T A;  4EC3 A;  5AE1 A;  3D2J A;  2R2Z A;  4PVJ A;  2P4P A;  1WYG A;  3BW7 A;  5D79 A;  2WDW A;  2Y3S A;  1AHV A;  3NVW B;  3S1F A;  2VAO A;  1W1L A;  3HRD C;  5AE2 A;  5HMR A;  2NQW A;  2GQT A;  3VTE A;  4BCA A;  5L6G A;  2IPI A;  2UUV A;  3PM9 A;  2GQU A;  2Q4W A;  4PVK A;  4MLA A;  2AXR A;  2VFV A;  5G5G B;  1V97 A;  3NRZ B;  3AMZ A;  4OAL A;  3D2D A;  3DQ0 A;  1FFV C;  1N5W C;  1W1J A;  2VFU A;  2QKN A;  1FIQ B;  1N62 C;  1DIQ A;  3B9J B;  1W1O A;  4JAY A;  3S1D A;  2VFT A;  1ZR6 A;  3W8Z A;  3FW8 A;  2UUU A;  1N5X A;  2YVS A;  5FXP A;  2I0K A;  2PLI A;  4PVE A;  4BC9 A;  4ML8 A;  3LLB A;  1JRP A;  1AHU A;  3TSJ A;  2Q85 A;  1JRO A;  5AWV A;  1FFU C;  1W1Q A;  4PWB A;  3NVV B;  4XLO A;  4UD8 A;  1SB3 B;  3HSU A;  3RJ8 A;  3KJM A;  1E8H A;  1DZN A;  5HHZ A;  5K8E A;  2QPM A;  2W3R A;  4BBY A;  1UXY A;  4O95 A;  1N61 C;  1MBT A;  1T3Q C;  5ADZ A;  2R8D A;  2W54 A;  5I1W A;  4PWC A;  1QLT A;  2PLS A;  3NS1 B;  2Y4G A;  4PVH A;  1W1M A;  3FW7 A;  4DNS A;  1N60 C;  4PZF A;  3C0P A;  1MBB A;  3EJD B;  2OAI A;  3RJA A;  5L6F A;  2O3G A;  2W3S A;  2P13 A;  3LAE A;  1E8G A;  2Y3R A;  5G5H B;  4HG0 A;  5I1V A;  2W55 A;  5HQX A;  2VFR A;  3TX1 A;  1N63 C;  3W8W A;  1HSK A;  1I19 A;  3NVZ B;  4BC7 A;  3EJE B;  1VAO A;  1WVE A;  1E8F A;  2RK5 A;  3S1E A;  3EUB 3;  3ETR B;  3JS8 A;  5FXD A;  4ZOH B;  1RM6 B;  4PYT A;  2BVF A;  1E0Y A;  3DED A;  3SR6 B;  1W1R A;  3POP A;  1VDV A;  1ZXI C;  3AN1 A;  3D2H A;  1DII A;  1F0X A;  5FXE A;  1AHZ A;  1FO4 A;  2P3H A;  5AE3 A; 
#chains in the Genus database with same CATH homology
 3GSY A;  1W1S A;  2BVG A;  3S1C A;  3NVY B;  2Y08 A;  3FWA A;  4JB1 A;  3PQB A;  2EXR A;  3I99 A;  3W8X A;  1W1K A;  1WVF A;  3TSH A;  3FW9 A;  2BVH A;  2VFS A;  3AM9 A;  1QLU A;  5FXF A;  2MBR A;  2E3T A;  4EC3 A;  5AE1 A;  3D2J A;  2R2Z A;  4PVJ A;  2P4P A;  1WYG A;  3BW7 A;  5D79 A;  2WDW A;  2Y3S A;  1AHV A;  3NVW B;  3S1F A;  2VAO A;  1W1L A;  3HRD C;  5AE2 A;  5HMR A;  2NQW A;  2GQT A;  3VTE A;  4BCA A;  5L6G A;  2IPI A;  2UUV A;  3PM9 A;  2GQU A;  2Q4W A;  4PVK A;  4MLA A;  2AXR A;  2VFV A;  5G5G B;  1V97 A;  3NRZ B;  3AMZ A;  4OAL A;  3D2D A;  3DQ0 A;  1FFV C;  1N5W C;  1W1J A;  2VFU A;  2QKN A;  1FIQ B;  1N62 C;  1DIQ A;  3B9J B;  1W1O A;  4JAY A;  3S1D A;  2VFT A;  1ZR6 A;  3W8Z A;  3FW8 A;  2UUU A;  1N5X A;  2YVS A;  5FXP A;  2I0K A;  2PLI A;  4PVE A;  4BC9 A;  4ML8 A;  3LLB A;  1JRP A;  1AHU A;  3TSJ A;  2Q85 A;  1JRO A;  5AWV A;  1FFU C;  1W1Q A;  4PWB A;  3NVV B;  4XLO A;  4UD8 A;  1SB3 B;  3HSU A;  3RJ8 A;  3KJM A;  1E8H A;  1DZN A;  5HHZ A;  5K8E A;  2QPM A;  2W3R A;  4BBY A;  1UXY A;  4O95 A;  1N61 C;  1MBT A;  1T3Q C;  5ADZ A;  2R8D A;  2W54 A;  5I1W A;  4PWC A;  1QLT A;  2PLS A;  3NS1 B;  2Y4G A;  4PVH A;  1W1M A;  3FW7 A;  4DNS A;  1N60 C;  4PZF A;  3C0P A;  1MBB A;  3RJA A;  2OAI A;  5L6F A;  2O3G A;  2W3S A;  2P13 A;  3LAE A;  1E8G A;  2Y3R A;  5G5H B;  4HG0 A;  5I1V A;  2W55 A;  5HQX A;  2VFR A;  3TX1 A;  1N63 C;  3W8W A;  1HSK A;  1I19 A;  3NVZ B;  4BC7 A;  1VAO A;  1WVE A;  1E8F A;  2RK5 A;  3S1E A;  3EUB 3;  3ETR B;  3JS8 A;  5FXD A;  4ZOH B;  1RM6 B;  4PYT A;  2BVF A;  1E0Y A;  3DED A;  3SR6 B;  1W1R A;  3POP A;  1VDV A;  1ZXI C;  3AN1 A;  3D2H A;  1DII A;  1F0X A;  5FXE A;  1AHZ A;  1FO4 A;  2P3H A;  5AE3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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