2Q85A

Crystal structure of e. coli mur b bound to a naphthyl tetronic acid inihibitor
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
341
structure length
341
Chain Sequence
NHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDSVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKGMQIGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGEVSAVETIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of E. Coli Mur B bound to a napthyl tetronic acid inhibitor
rcsb
molecule tags Oxidoreductase
molecule keywords UDP-N-acetylenolpyruvoylglucosamine reductase
total genus 101
structure length 341
sequence length 341
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2007-06-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 2q85A01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 2q85A02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 2q85A03
4O95A 1FFUC 1HSKA 2Q4WA 3HRDC 3LAEA 1SB3B 3NVWB 1W1QA 1WVFA 2EXRA 2RK5A 2GQUA 3NS1B 2BVFA 2QPMA 4OALA 1MBBA 1W1KA 1W1RA 2BVGA 4PYTA 1DIIA 1DZNA 3D2DA 4PWBA 2MBRA 3S1CA 3NVVB 2P3HA 1N60C 4XLOA 3C0PA 1ZR6A 2VFSA 2O3GA 3TSHA 5ADZA 1N62C 1W1MA 4DNSA 3BW7A 3FW7A 5G5HB 1QLUA 5HQXA 1E0YA 1AHZA 1WYGA 4MLAA 2W3RA 1W1JA 4JB1A 1V97A 3NVZB 2E3TA 3D2JA 4BC9A 2AXRA 5AE2A 3EUB3 3S1FA 4BCAA 1E8GA 4PVEA 1VAOA 4PZFA 1UXYA 3W8XA 5AE1A 5FXEA 3LLBA 3KJMA 3DEDA 3VTEA 3DQ0A 1W1OA 3TSJA 2QKNA 5HHZA 5G5GB 4JAYA 2VAOA 3ETRB 4BC7A 3SR6B 2R8DA 3W8ZA 1JROA 4ML8A 3FW9A 3I99A 2VFUA 2P4PA 2GQTA 2BVHA 1QLTA 2VFTA 4PWCA 1N5XA 3FW8A 4UD8A 1JRPA 5FXPA 3NVYB 3AN1A 5AE3A 1W1LA 5FXFA 2YVSA 1E8FA 4PVJA 1WVEA 1N61C 3S1DA 3TX1A 1VDVA 1FIQB 1AHVA 3AM9A 5FXDA 1ZXIC 3NRZB 1E8HA 3B9JB 3S1EA 4PVKA 3PM9A 2Q85A 1N5WC 2R2ZA 1FO4A 3GSYA 4HG0A 1I19A 1W1SA 3FWAA 1MBTA 1F0XA 1FFVC 2I0KA 2W55A 2PLSA 3W8WA 2NQWA 1RM6B 2OAIA 4BBYA 3JS8A 1T3QC 2PLIA 5D79A 1DIQA 5HMRA 2W54A 1AHUA 4PVHA 2W3SA 2P13A 4EC3A 3AMZA 2VFVA 3D2HA 1N63C 2VFRA 4ZOHB
chains in the Genus database with same CATH superfamily
4O95A 1FFUC 1HSKA 2Q4WA 3HRDC 3LAEA 1SB3B 3NVWB 1W1QA 1WVFA 2EXRA 2RK5A 2GQUA 3NS1B 2BVFA 2QPMA 4OALA 1MBBA 1W1KA 1W1RA 5I1VA 2BVGA 4PYTA 1DIIA 1DZNA 3D2DA 4PWBA 2MBRA 3NVVB 3S1CA 2P3HA 1N60C 4XLOA 5AWVA 3C0PA 1ZR6A 2VFSA 2O3GA 3TSHA 5ADZA 1N62C 1W1MA 3EJDB 4DNSA 3HSUA 3BW7A 3FW7A 5G5HB 1QLUA 2Y4GA 5HQXA 1E0YA 1AHZA 1WYGA 4MLAA 2W3RA 1W1JA 4JB1A 1V97A 3NVZB 2E3TA 5K8EA 3D2JA 4BC9A 2AXRA 5AE2A 3EUB3 3S1FA 4BCAA 1E8GA 4PVEA 1VAOA 4PZFA 1UXYA 3W8XA 5AE1A 5L6GA 5FXEA 3LLBA 3KJMA 3DEDA 3POPA 3VTEA 3DQ0A 1W1OA 3EJBB 3TSJA 2UUUA 2QKNA 5HHZA 5G5GB 4JAYA 2VAOA 3ETRB 4BC7A 3SR6B 3RJ8A 2R8DA 3W8ZA 1JROA 4ML8A 3FW9A 3I99A 2VFUA 2P4PA 2Y3SA 2GQTA 5I1WA 2BVHA 1QLTA 2VFTA 4PWCA 1N5XA 3FW8A 4UD8A 1JRPA 5FXPA 3NVYB 3AN1A 5AE3A 1W1LA 5FXFA 2YVSA 2IPIA 1E8FA 4PVJA 3PQBA 1WVEA 1N61C 3S1DA 3TX1A 1VDVA 1FIQB 1AHVA 3AM9A 5FXDA 1ZXIC 2UUVA 3RJAA 3NRZB 1E8HA 3B9JB 3S1EA 4PVKA 3PM9A 2Q85A 1N5WC 2R2ZA 1FO4A 3GSYA 2WDWA 4HG0A 1I19A 1W1SA 3FWAA 1MBTA 1F0XA 3EJEB 2Y3RA 1FFVC 2I0KA 2W55A 2PLSA 3W8WA 2NQWA 1RM6B 2OAIA 4BBYA 3JS8A 1T3QC 2PLIA 5D79A 1DIQA 5HMRA 2W54A 1AHUA 4PVHA 2W3SA 2P13A 4EC3A 3AMZA 5L6FA 2VFVA 3D2HA 1N63C 2VFRA 4ZOHB 2Y08A
chains in the Genus database with same CATH topology
4O95A 1FFUC 1HSKA 2Q4WA 3HRDC 3LAEA 1SB3B 3NVWB 1W1QA 1WVFA 2EXRA 2RK5A 2GQUA 3NS1B 2BVFA 2QPMA 4OALA 1MBBA 1W1KA 1W1RA 5I1VA 2BVGA 4PYTA 1DIIA 1DZNA 3D2DA 4PWBA 2MBRA 3S1CA 3NVVB 2P3HA 1N60C 4XLOA 5AWVA 3C0PA 1ZR6A 2VFSA 2O3GA 3TSHA 5ADZA 1N62C 1W1MA 3HSUA 4DNSA 3BW7A 3FW7A 5G5HB 1QLUA 2Y4GA 5HQXA 1E0YA 1AHZA 1WYGA 4MLAA 2W3RA 1W1JA 4JB1A 1V97A 3NVZB 2E3TA 5K8EA 3D2JA 4BC9A 2AXRA 5AE2A 3EUB3 3S1FA 4BCAA 1E8GA 4PVEA 1VAOA 4PZFA 1UXYA 3W8XA 5AE1A 5L6GA 5FXEA 3LLBA 3KJMA 3DEDA 3POPA 3VTEA 3DQ0A 1W1OA 3TSJA 2UUUA 2QKNA 5HHZA 5G5GB 4JAYA 2VAOA 3ETRB 4BC7A 3SR6B 3RJ8A 2R8DA 3W8ZA 1JROA 4ML8A 3FW9A 3I99A 2VFUA 2P4PA 2Y3SA 2GQTA 5I1WA 2BVHA 1QLTA 2VFTA 4PWCA 1N5XA 3FW8A 4UD8A 1JRPA 5FXPA 3NVYB 3AN1A 5AE3A 1W1LA 5FXFA 2YVSA 2IPIA 1E8FA 4PVJA 3PQBA 1WVEA 1N61C 3S1DA 3TX1A 1VDVA 1FIQB 1AHVA 3AM9A 5FXDA 1ZXIC 2UUVA 3RJAA 3NRZB 1E8HA 3B9JB 3S1EA 4PVKA 3PM9A 2Q85A 1N5WC 2R2ZA 1FO4A 3GSYA 2WDWA 4HG0A 1I19A 1W1SA 3FWAA 1MBTA 1F0XA 2Y3RA 1FFVC 2I0KA 2W55A 2PLSA 3W8WA 2NQWA 1RM6B 2OAIA 4BBYA 3JS8A 1T3QC 2PLIA 5D79A 1DIQA 5HMRA 2W54A 1AHUA 4PVHA 2W3SA 2P13A 4EC3A 3AMZA 5L6FA 2VFVA 3D2HA 1N63C 2VFRA 4ZOHB 2Y08A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O95 A;  1FFU C;  1HSK A;  2Q4W A;  3HRD C;  3LAE A;  1SB3 B;  3NVW B;  1W1Q A;  1WVF A;  2EXR A;  2RK5 A;  2GQU A;  3NS1 B;  2BVF A;  2QPM A;  4OAL A;  1MBB A;  1W1K A;  1W1R A;  2BVG A;  4PYT A;  1DII A;  1DZN A;  3D2D A;  4PWB A;  2MBR A;  3S1C A;  3NVV B;  2P3H A;  1N60 C;  4XLO A;  3C0P A;  1ZR6 A;  2VFS A;  2O3G A;  3TSH A;  5ADZ A;  1N62 C;  1W1M A;  4DNS A;  3BW7 A;  3FW7 A;  5G5H B;  1QLU A;  5HQX A;  1E0Y A;  1AHZ A;  1WYG A;  4MLA A;  2W3R A;  1W1J A;  4JB1 A;  1V97 A;  3NVZ B;  2E3T A;  3D2J A;  4BC9 A;  2AXR A;  5AE2 A;  3EUB 3;  3S1F A;  4BCA A;  1E8G A;  4PVE A;  1VAO A;  4PZF A;  1UXY A;  3W8X A;  5AE1 A;  5FXE A;  3LLB A;  3KJM A;  3DED A;  3VTE A;  3DQ0 A;  1W1O A;  3TSJ A;  2QKN A;  5HHZ A;  5G5G B;  4JAY A;  2VAO A;  3ETR B;  4BC7 A;  3SR6 B;  2R8D A;  3W8Z A;  1JRO A;  4ML8 A;  3FW9 A;  3I99 A;  2VFU A;  2P4P A;  2GQT A;  2BVH A;  1QLT A;  2VFT A;  4PWC A;  1N5X A;  3FW8 A;  4UD8 A;  1JRP A;  5FXP A;  3NVY B;  3AN1 A;  5AE3 A;  1W1L A;  5FXF A;  2YVS A;  1E8F A;  4PVJ A;  1WVE A;  1N61 C;  3S1D A;  3TX1 A;  1VDV A;  1FIQ B;  1AHV A;  3AM9 A;  5FXD A;  1ZXI C;  3NRZ B;  1E8H A;  3B9J B;  3S1E A;  4PVK A;  3PM9 A;  2Q85 A;  1N5W C;  2R2Z A;  1FO4 A;  3GSY A;  4HG0 A;  1I19 A;  1W1S A;  3FWA A;  1MBT A;  1F0X A;  1FFV C;  2I0K A;  2W55 A;  2PLS A;  3W8W A;  2NQW A;  1RM6 B;  2OAI A;  4BBY A;  3JS8 A;  1T3Q C;  2PLI A;  5D79 A;  1DIQ A;  5HMR A;  2W54 A;  1AHU A;  4PVH A;  2W3S A;  2P13 A;  4EC3 A;  3AMZ A;  2VFV A;  3D2H A;  1N63 C;  2VFR A;  4ZOH B; 
#chains in the Genus database with same CATH topology
 4O95 A;  1FFU C;  1HSK A;  2Q4W A;  3HRD C;  3LAE A;  1SB3 B;  3NVW B;  1W1Q A;  1WVF A;  2EXR A;  2RK5 A;  2GQU A;  3NS1 B;  2BVF A;  2QPM A;  4OAL A;  1MBB A;  1W1K A;  1W1R A;  5I1V A;  2BVG A;  4PYT A;  1DII A;  1DZN A;  3D2D A;  4PWB A;  2MBR A;  3NVV B;  3S1C A;  2P3H A;  1N60 C;  4XLO A;  5AWV A;  3C0P A;  1ZR6 A;  2VFS A;  2O3G A;  3TSH A;  5ADZ A;  1N62 C;  1W1M A;  3EJD B;  4DNS A;  3HSU A;  3BW7 A;  3FW7 A;  5G5H B;  1QLU A;  2Y4G A;  5HQX A;  1E0Y A;  1AHZ A;  1WYG A;  4MLA A;  2W3R A;  1W1J A;  4JB1 A;  1V97 A;  3NVZ B;  2E3T A;  5K8E A;  3D2J A;  4BC9 A;  2AXR A;  5AE2 A;  3EUB 3;  3S1F A;  4BCA A;  1E8G A;  4PVE A;  1VAO A;  4PZF A;  1UXY A;  3W8X A;  5AE1 A;  5L6G A;  5FXE A;  3LLB A;  3KJM A;  3DED A;  3POP A;  3VTE A;  3DQ0 A;  1W1O A;  3EJB B;  3TSJ A;  2UUU A;  2QKN A;  5HHZ A;  5G5G B;  4JAY A;  2VAO A;  3ETR B;  4BC7 A;  3SR6 B;  3RJ8 A;  2R8D A;  3W8Z A;  1JRO A;  4ML8 A;  3FW9 A;  3I99 A;  2VFU A;  2P4P A;  2Y3S A;  2GQT A;  5I1W A;  2BVH A;  1QLT A;  2VFT A;  4PWC A;  1N5X A;  3FW8 A;  4UD8 A;  1JRP A;  5FXP A;  3NVY B;  3AN1 A;  5AE3 A;  1W1L A;  5FXF A;  2YVS A;  2IPI A;  1E8F A;  4PVJ A;  3PQB A;  1WVE A;  1N61 C;  3S1D A;  3TX1 A;  1VDV A;  1FIQ B;  1AHV A;  3AM9 A;  5FXD A;  1ZXI C;  2UUV A;  3RJA A;  3NRZ B;  1E8H A;  3B9J B;  3S1E A;  4PVK A;  3PM9 A;  2Q85 A;  1N5W C;  2R2Z A;  1FO4 A;  3GSY A;  2WDW A;  4HG0 A;  1I19 A;  1W1S A;  3FWA A;  1MBT A;  1F0X A;  3EJE B;  2Y3R A;  1FFV C;  2I0K A;  2W55 A;  2PLS A;  3W8W A;  2NQW A;  1RM6 B;  2OAI A;  4BBY A;  3JS8 A;  1T3Q C;  2PLI A;  5D79 A;  1DIQ A;  5HMR A;  2W54 A;  1AHU A;  4PVH A;  2W3S A;  2P13 A;  4EC3 A;  3AMZ A;  5L6F A;  2VFV A;  3D2H A;  1N63 C;  2VFR A;  4ZOH B;  2Y08 A; 
#chains in the Genus database with same CATH homology
 4O95 A;  1FFU C;  1HSK A;  2Q4W A;  3HRD C;  3LAE A;  1SB3 B;  3NVW B;  1W1Q A;  1WVF A;  2EXR A;  2RK5 A;  2GQU A;  3NS1 B;  2BVF A;  2QPM A;  4OAL A;  1MBB A;  1W1K A;  1W1R A;  5I1V A;  2BVG A;  4PYT A;  1DII A;  1DZN A;  3D2D A;  4PWB A;  2MBR A;  3S1C A;  3NVV B;  2P3H A;  1N60 C;  4XLO A;  5AWV A;  3C0P A;  1ZR6 A;  2VFS A;  2O3G A;  3TSH A;  5ADZ A;  1N62 C;  1W1M A;  3HSU A;  4DNS A;  3BW7 A;  3FW7 A;  5G5H B;  1QLU A;  2Y4G A;  5HQX A;  1E0Y A;  1AHZ A;  1WYG A;  4MLA A;  2W3R A;  1W1J A;  4JB1 A;  1V97 A;  3NVZ B;  2E3T A;  5K8E A;  3D2J A;  4BC9 A;  2AXR A;  5AE2 A;  3EUB 3;  3S1F A;  4BCA A;  1E8G A;  4PVE A;  1VAO A;  4PZF A;  1UXY A;  3W8X A;  5AE1 A;  5L6G A;  5FXE A;  3LLB A;  3KJM A;  3DED A;  3POP A;  3VTE A;  3DQ0 A;  1W1O A;  3TSJ A;  2UUU A;  2QKN A;  5HHZ A;  5G5G B;  4JAY A;  2VAO A;  3ETR B;  4BC7 A;  3SR6 B;  3RJ8 A;  2R8D A;  3W8Z A;  1JRO A;  4ML8 A;  3FW9 A;  3I99 A;  2VFU A;  2P4P A;  2Y3S A;  2GQT A;  5I1W A;  2BVH A;  1QLT A;  2VFT A;  4PWC A;  1N5X A;  3FW8 A;  4UD8 A;  1JRP A;  5FXP A;  3NVY B;  3AN1 A;  5AE3 A;  1W1L A;  5FXF A;  2YVS A;  2IPI A;  1E8F A;  4PVJ A;  3PQB A;  1WVE A;  1N61 C;  3S1D A;  3TX1 A;  1VDV A;  1FIQ B;  1AHV A;  3AM9 A;  5FXD A;  1ZXI C;  2UUV A;  3RJA A;  3NRZ B;  1E8H A;  3B9J B;  3S1E A;  4PVK A;  3PM9 A;  2Q85 A;  1N5W C;  2R2Z A;  1FO4 A;  3GSY A;  2WDW A;  4HG0 A;  1I19 A;  1W1S A;  3FWA A;  1MBT A;  1F0X A;  2Y3R A;  1FFV C;  2I0K A;  2W55 A;  2PLS A;  3W8W A;  2NQW A;  1RM6 B;  2OAI A;  4BBY A;  3JS8 A;  1T3Q C;  2PLI A;  5D79 A;  1DIQ A;  5HMR A;  2W54 A;  1AHU A;  4PVH A;  2W3S A;  2P13 A;  4EC3 A;  3AMZ A;  5L6F A;  2VFV A;  3D2H A;  1N63 C;  2VFR A;  4ZOH B;  2Y08 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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