3PQBA

The crystal structure of pregilvocarcin in complex with gilr, an oxidoreductase that catalyzes the terminal step of gilvocarcin biosynthesis
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
492
structure length
492
Chain Sequence
PFTVGREDPRYIELSHSDNHRFVVEPEEFFLPATPDDVVASLQKAVTEGRGVACRSGGHCGQDFVGTPRRDLVLDLHNLHAIGPAADGAGVRVGSGATVDQVQKALFRRWNAALPLGACSAVGMGGLVAGGGYGPLSRQLGLVVDHLHAVEVAVVDESRTVRLVTARADDTGDLGELFWAHTGGGGGNFGVVTAYEFRSPEHLATEPVGLPRAAGRLHVQKVVFPWAMIDETSFVTVMRRFFEWHERHSEPGSPESSLFATFFVNHVSSGVLQLMVQQDADVDPEGEILARFVASLTEGTGVVGIPRGGVMSWLTGTRYMSQADCGDVMGARSASKSAYHRAAPTDEQLSVLHRHLHADHPGQASYVMFNSYGGEINRRGPSDAAVPQRDSVVKSSWFSAWQDAELDELHLGWLRGLYEEFFAGTGGVPVTGGRTDGCYINYPDADLLDPARNRSGEPWHHLYYKDNYARLRSAKRAWDPLNTFHHSMSIGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Streptomyces griseoflavus
molecule keywords Putative oxidoreductase
total genus 165
structure length 492
sequence length 492
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.465.40 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3pqbA01
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3pqbA02
3W8WA 2BVHA 5L6FA 3FW9A 5K8EA 4XLOA 4EC3A 5L6GA 2Y08A 4PVEA 3RJAA 2BVGA 3FW7A 2UUUA 2IPIA 5D79A 2UUVA 2Y3SA 3PQBA 4PVHA 2AXRA 3W8ZA 5I1WA 3FWAA 3TSHA 3POPA 3D2HA 2Y3RA 3GSYA 4PZFA 4PWBA 3TSJA 4PVKA 3D2DA 4PWCA 3VTEA 2Y4GA 3W8XA 3RJ8A 2WDWA 1ZR6A 4UD8A 2BVFA 5AWVA 4DNSA 3HSUA 5I1VA 4PVJA 3FW8A 3D2JA
chains in the Genus database with same CATH superfamily
1W1MA 2BVHA 2Q4WA 1JRPA 5G5GB 2W54A 1E8HA 2BVGA 2W55A 1VAOA 2UUUA 2W3SA 2W3RA 2IPIA 1WVEA 2MBRA 2UUVA 3PQBA 2VAOA 1F0XA 2R2ZA 1E8FA 2RK5A 5FXDA 5I1WA 1FFUC 3POPA 2Y3RA 3B9JB 5FXFA 1N60C 4O95A 1RM6B 3TSJA 5ADZA 3W8XA 4PYTA 3BW7A 1DIQA 2NQWA 3VTEA 4HG0A 2PLSA 2WDWA 3EUB3 1ZR6A 4UD8A 4DNSA 1AHZA 2PLIA 2VFRA 1HSKA 5FXEA 5I1VA 1FFVC 2VFSA 3PM9A 1W1OA 3DQ0A 3S1DA 2Q85A 3SR6B 1SB3B 1N61C 1JROA 1MBBA 4BC9A 1AHUA 5D79A 3DEDA 3NVZB 4MLAA 3S1FA 3FWAA 3TSHA 2VFUA 4PZFA 1N5XA 4PVKA 5HHZA 1W1SA 2O3GA 2Y4GA 2VFVA 1ZXIC 4OALA 4PVJA 1FO4A 5FXPA 1N63C 2GQUA 2P3HA 3W8WA 3AN1A 4ZOHB 1W1JA 3FW9A 5L6FA 4EC3A 5AE3A 2P4PA 1W1KA 1V97A 5AE1A 1FIQB 3S1CA 2E3TA 3RJAA 1VDVA 5HQXA 2R8DA 4BCAA 1W1RA 3C0PA 2AXRA 1DIIA 3NVVB 3I99A 3HRDC 2YVSA 1N62C 2P13A 5AE2A 3D2HA 1WYGA 4JAYA 3AM9A 1T3QC 5G5HB 2VFTA 2QKNA 1AHVA 3LLBA 1WVFA 1MBTA 3HSUA 3KJMA 3NVWB 1E0YA 3JS8A 3FW8A 2QPMA 1UXYA 4XLOA 5K8EA 2GQTA 1I19A 1DZNA 5L6GA 2Y08A 4PVEA 3FW7A 2EXRA 3NVYB 3ETRB 1W1LA 2Y3SA 4PVHA 1E8GA 2I0KA 2OAIA 3W8ZA 4ML8A 5HMRA 3LAEA 1QLTA 3TX1A 3S1EA 4BBYA 3GSYA 4PWBA 3D2DA 4PWCA 3RJ8A 1QLUA 3AMZA 3NS1B 1N5WC 4BC7A 2BVFA 4JB1A 5AWVA 1W1QA 3D2JA 3NRZB
chains in the Genus database with same CATH topology
1W1MA 2BVHA 2Q4WA 1JRPA 5G5GB 2W54A 1E8HA 2BVGA 2W55A 1VAOA 2UUUA 2W3SA 2W3RA 2IPIA 1WVEA 2MBRA 2UUVA 3PQBA 2VAOA 1F0XA 2R2ZA 1E8FA 2RK5A 5FXDA 5I1WA 1FFUC 3POPA 2Y3RA 3B9JB 5FXFA 1N60C 4O95A 1RM6B 3TSJA 5ADZA 3W8XA 4PYTA 3BW7A 1DIQA 2NQWA 3VTEA 4HG0A 2PLSA 2WDWA 3EUB3 1ZR6A 4UD8A 4DNSA 1AHZA 2PLIA 2VFRA 1HSKA 5FXEA 5I1VA 1FFVC 2VFSA 3PM9A 1W1OA 3DQ0A 3S1DA 2Q85A 3SR6B 1SB3B 1N61C 1JROA 1MBBA 4BC9A 1AHUA 5D79A 3DEDA 3NVZB 4MLAA 3S1FA 3FWAA 3TSHA 2VFUA 4PZFA 1N5XA 4PVKA 5HHZA 1W1SA 2O3GA 2Y4GA 2VFVA 1ZXIC 4OALA 4PVJA 1FO4A 5FXPA 1N63C 2GQUA 2P3HA 3W8WA 3AN1A 4ZOHB 1W1JA 3FW9A 5L6FA 4EC3A 5AE3A 2P4PA 1W1KA 1V97A 5AE1A 1FIQB 3S1CA 2E3TA 3RJAA 1VDVA 5HQXA 2R8DA 4BCAA 1W1RA 3C0PA 2AXRA 1DIIA 3NVVB 3I99A 3HRDC 2YVSA 1N62C 2P13A 5AE2A 3D2HA 1WYGA 4JAYA 3AM9A 1T3QC 5G5HB 2VFTA 2QKNA 1AHVA 3LLBA 1WVFA 1MBTA 3HSUA 3KJMA 3NVWB 1E0YA 3JS8A 3FW8A 2QPMA 1UXYA 4XLOA 5K8EA 2GQTA 1I19A 1DZNA 5L6GA 2Y08A 4PVEA 3FW7A 2EXRA 3NVYB 3ETRB 1W1LA 2Y3SA 4PVHA 1E8GA 2I0KA 2OAIA 3W8ZA 4ML8A 5HMRA 3LAEA 1QLTA 3TX1A 3S1EA 4BBYA 3GSYA 4PWBA 3D2DA 4PWCA 3RJ8A 1QLUA 3AMZA 3NS1B 1N5WC 4BC7A 2BVFA 4JB1A 5AWVA 1W1QA 3D2JA 3NRZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W8W A;  2BVH A;  5L6F A;  3FW9 A;  5K8E A;  4XLO A;  4EC3 A;  5L6G A;  2Y08 A;  4PVE A;  3RJA A;  2BVG A;  3FW7 A;  2UUU A;  2IPI A;  5D79 A;  2UUV A;  2Y3S A;  3PQB A;  4PVH A;  2AXR A;  3W8Z A;  5I1W A;  3FWA A;  3TSH A;  3POP A;  3D2H A;  2Y3R A;  3GSY A;  4PZF A;  4PWB A;  3TSJ A;  4PVK A;  3D2D A;  4PWC A;  3VTE A;  2Y4G A;  3W8X A;  3RJ8 A;  2WDW A;  1ZR6 A;  4UD8 A;  2BVF A;  5AWV A;  4DNS A;  3HSU A;  5I1V A;  4PVJ A;  3FW8 A;  3D2J A; 
#chains in the Genus database with same CATH topology
 1W1M A;  2BVH A;  2Q4W A;  1JRP A;  5G5G B;  2W54 A;  1E8H A;  2BVG A;  2W55 A;  1VAO A;  2UUU A;  2W3S A;  2W3R A;  2IPI A;  1WVE A;  2MBR A;  2UUV A;  3PQB A;  2VAO A;  1F0X A;  2R2Z A;  1E8F A;  2RK5 A;  5FXD A;  5I1W A;  1FFU C;  3POP A;  2Y3R A;  3B9J B;  5FXF A;  1N60 C;  4O95 A;  1RM6 B;  3TSJ A;  5ADZ A;  3W8X A;  4PYT A;  3BW7 A;  1DIQ A;  2NQW A;  3VTE A;  4HG0 A;  2PLS A;  2WDW A;  3EUB 3;  1ZR6 A;  4UD8 A;  4DNS A;  1AHZ A;  2PLI A;  2VFR A;  1HSK A;  5FXE A;  5I1V A;  1FFV C;  2VFS A;  3PM9 A;  1W1O A;  3DQ0 A;  3S1D A;  2Q85 A;  3SR6 B;  1SB3 B;  1N61 C;  1JRO A;  1MBB A;  4BC9 A;  1AHU A;  5D79 A;  3DED A;  3NVZ B;  4MLA A;  3S1F A;  3FWA A;  3TSH A;  2VFU A;  4PZF A;  1N5X A;  4PVK A;  5HHZ A;  1W1S A;  2O3G A;  2Y4G A;  2VFV A;  1ZXI C;  4OAL A;  4PVJ A;  1FO4 A;  5FXP A;  1N63 C;  2GQU A;  2P3H A;  3W8W A;  3AN1 A;  4ZOH B;  1W1J A;  3FW9 A;  5L6F A;  4EC3 A;  5AE3 A;  2P4P A;  1W1K A;  1V97 A;  5AE1 A;  1FIQ B;  3S1C A;  2E3T A;  3RJA A;  1VDV A;  5HQX A;  2R8D A;  4BCA A;  1W1R A;  3C0P A;  2AXR A;  1DII A;  3NVV B;  3I99 A;  3HRD C;  2YVS A;  1N62 C;  2P13 A;  5AE2 A;  3D2H A;  1WYG A;  4JAY A;  3AM9 A;  1T3Q C;  5G5H B;  2VFT A;  2QKN A;  1AHV A;  3LLB A;  1WVF A;  1MBT A;  3HSU A;  3KJM A;  3NVW B;  1E0Y A;  3JS8 A;  3FW8 A;  2QPM A;  1UXY A;  4XLO A;  5K8E A;  2GQT A;  1I19 A;  1DZN A;  5L6G A;  2Y08 A;  4PVE A;  3FW7 A;  2EXR A;  3NVY B;  3ETR B;  1W1L A;  2Y3S A;  4PVH A;  1E8G A;  2I0K A;  2OAI A;  3W8Z A;  4ML8 A;  5HMR A;  3LAE A;  1QLT A;  3TX1 A;  3S1E A;  4BBY A;  3GSY A;  4PWB A;  3D2D A;  4PWC A;  3RJ8 A;  1QLU A;  3AMZ A;  3NS1 B;  1N5W C;  4BC7 A;  2BVF A;  4JB1 A;  5AWV A;  1W1Q A;  3D2J A;  3NRZ B; 
#chains in the Genus database with same CATH homology
 1W1M A;  2BVH A;  2Q4W A;  1JRP A;  5G5G B;  2W54 A;  1E8H A;  2BVG A;  2W55 A;  1VAO A;  2UUU A;  2W3S A;  2W3R A;  2IPI A;  1WVE A;  2MBR A;  2UUV A;  3PQB A;  2VAO A;  1F0X A;  2R2Z A;  1E8F A;  2RK5 A;  5FXD A;  5I1W A;  1FFU C;  3POP A;  2Y3R A;  3B9J B;  5FXF A;  1N60 C;  4O95 A;  1RM6 B;  3TSJ A;  5ADZ A;  3W8X A;  4PYT A;  3BW7 A;  1DIQ A;  2NQW A;  3VTE A;  4HG0 A;  2PLS A;  2WDW A;  3EUB 3;  1ZR6 A;  4UD8 A;  4DNS A;  1AHZ A;  2PLI A;  2VFR A;  1HSK A;  5FXE A;  5I1V A;  1FFV C;  2VFS A;  3PM9 A;  1W1O A;  3DQ0 A;  3S1D A;  2Q85 A;  3SR6 B;  1SB3 B;  1N61 C;  1JRO A;  1MBB A;  4BC9 A;  1AHU A;  5D79 A;  3DED A;  3NVZ B;  4MLA A;  3S1F A;  3FWA A;  3TSH A;  2VFU A;  4PZF A;  1N5X A;  4PVK A;  5HHZ A;  1W1S A;  2O3G A;  2Y4G A;  2VFV A;  1ZXI C;  4OAL A;  4PVJ A;  1FO4 A;  5FXP A;  1N63 C;  2GQU A;  2P3H A;  3W8W A;  3AN1 A;  4ZOH B;  1W1J A;  3FW9 A;  5L6F A;  4EC3 A;  5AE3 A;  2P4P A;  1W1K A;  1V97 A;  5AE1 A;  1FIQ B;  3S1C A;  2E3T A;  3RJA A;  1VDV A;  5HQX A;  2R8D A;  4BCA A;  1W1R A;  3C0P A;  2AXR A;  1DII A;  3NVV B;  3I99 A;  3HRD C;  2YVS A;  1N62 C;  2P13 A;  5AE2 A;  3D2H A;  1WYG A;  4JAY A;  3AM9 A;  1T3Q C;  5G5H B;  2VFT A;  2QKN A;  1AHV A;  3LLB A;  1WVF A;  1MBT A;  3HSU A;  3KJM A;  3NVW B;  1E0Y A;  3JS8 A;  3FW8 A;  2QPM A;  1UXY A;  4XLO A;  5K8E A;  2GQT A;  1I19 A;  1DZN A;  5L6G A;  2Y08 A;  4PVE A;  3FW7 A;  2EXR A;  3NVY B;  3ETR B;  1W1L A;  2Y3S A;  4PVH A;  1E8G A;  2I0K A;  2OAI A;  3W8Z A;  4ML8 A;  5HMR A;  3LAE A;  1QLT A;  3TX1 A;  3S1E A;  4BBY A;  3GSY A;  4PWB A;  3D2D A;  4PWC A;  3RJ8 A;  1QLU A;  3AMZ A;  3NS1 B;  1N5W C;  4BC7 A;  2BVF A;  4JB1 A;  5AWV A;  1W1Q A;  3D2J A;  3NRZ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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