3PQBA

The crystal structure of pregilvocarcin in complex with gilr, an oxidoreductase that catalyzes the terminal step of gilvocarcin biosynthesis
Total Genus 165
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
492
structure length
492
Chain Sequence
PFTVGREDPRYIELSHSDNHRFVVEPEEFFLPATPDDVVASLQKAVTEGRGVACRSGGHCGQDFVGTPRRDLVLDLHNLHAIGPAADGAGVRVGSGATVDQVQKALFRRWNAALPLGACSAVGMGGLVAGGGYGPLSRQLGLVVDHLHAVEVAVVDESRTVRLVTARADDTGDLGELFWAHTGGGGGNFGVVTAYEFRSPEHLATEPVGLPRAAGRLHVQKVVFPWAMIDETSFVTVMRRFFEWHERHSEPGSPESSLFATFFVNHVSSGVLQLMVQQDADVDPEGEILARFVASLTEGTGVVGIPRGGVMSWLTGTRYMSQADCGDVMGARSASKSAYHRAAPTDEQLSVLHRHLHADHPGQASYVMFNSYGGEINRRGPSDAAVPQRDSVVKSSWFSAWQDAELDELHLGWLRGLYEEFFAGTGGVPVTGGRTDGCYINYPDADLLDPARNRSGEPWHHLYYKDNYARLRSAKRAWDPLNTFHHSMSIGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Streptomyces griseoflavus
molecule keywords Putative oxidoreductase
total genus 165
structure length 492
sequence length 492
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.465.40 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3pqbA01
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3pqbA02
3TSJA 5L6GA 3TSHA 2UUVA 2BVFA 3D2JA 2Y3SA 4UD8A 4PVJA 5D79A 5AWVA 2AXRA 4PWCA 2Y08A 3RJAA 3W8WA 2UUUA 5I1VA 4EC3A 3FW8A 3PQBA 3W8XA 3HSUA 1ZR6A 5L6FA 4PZFA 2IPIA 3RJ8A 4DNSA 3VTEA 3W8ZA 3FWAA 4PVKA 4XLOA 2BVGA 3GSYA 3POPA 3FW9A 2Y3RA 5I1WA 3D2DA 2WDWA 2BVHA 3D2HA 4PWBA 2Y4GA 3FW7A 4PVHA 5K8EA 4PVEA
chains in the Genus database with same CATH superfamily
1FFUC 5FXEA 1VAOA 3TSHA 1N63C 4ZOHB 2W55A 2BVFA 3LLBA 4UD8A 4PVJA 5AWVA 4BCAA 3RJAA 3W8WA 5AE2A 1QLUA 3S1EA 2QPMA 1V97A 3PQBA 2R8DA 1WYGA 1ZR6A 3I99A 1F0XA 2IPIA 3JS8A 3RJ8A 3NVWB 2VAOA 3AM9A 4JB1A 3VTEA 3W8ZA 3FWAA 4PVKA 1AHZA 2BVGA 3NRZB 4BC9A 1W1OA 3FW9A 4JAYA 2VFRA 1FO4A 3NVYB 3SR6B 3TX1A 4PWBA 3S1FA 1W1JA 1RM6B 1ZXIC 3FW7A 5G5GB 3NS1B 2Q4WA 4PVEA 2P4PA 1DIIA 2W3SA 5AE3A 3NVVB 1N61C 2W54A 1QLTA 2PLIA 2UUVA 1N62C 2R2ZA 3NVZB 3D2JA 2Y3SA 3S1DA 4PWCA 2Y08A 2VFVA 5HMRA 2UUUA 2I0KA 3DQ0A 2QKNA 1W1RA 3AMZA 1AHUA 1T3QC 3HSUA 5L6FA 4DNSA 2VFSA 5I1WA 1UXYA 1E0YA 1E8HA 2BVHA 2WDWA 3EUB3 2Y4GA 1AHVA 5ADZA 2EXRA 4BC7A 4MLAA 1HSKA 5L6GA 5FXPA 2E3TA 3ETRB 5D79A 2AXRA 2P3HA 5I1VA 2P13A 2GQTA 3AN1A 5HHZA 3PM9A 1DZNA 2VFUA 1WVEA 3S1CA 5FXFA 1SB3B 1W1KA 4XLOA 1W1QA 1VDVA 1I19A 2Y3RA 5FXDA 3LAEA 1DIQA 1FFVC 1N60C 2GQUA 3D2HA 4O95A 2O3GA 5G5HB 4ML8A 4EC3A 1N5XA 5K8EA 5HQXA 5AE1A 1N5WC 1W1LA 3KJMA 4HG0A 3TSJA 3B9JB 1FIQB 1W1MA 2MBRA 3FW8A 3W8XA 4PYTA 2YVSA 4PZFA 3HRDC 2NQWA 1MBTA 1E8GA 3DEDA 3GSYA 3POPA 2VFTA 1MBBA 1E8FA 2OAIA 1JRPA 2W3RA 3D2DA 4OALA 1W1SA 4BBYA 2RK5A 1WVFA 4PVHA 1JROA 2Q85A 3C0PA 3BW7A 2PLSA
chains in the Genus database with same CATH topology
1FFUC 5FXEA 1VAOA 3TSHA 1N63C 4ZOHB 2W55A 2BVFA 3LLBA 4UD8A 4PVJA 5AWVA 4BCAA 3RJAA 3W8WA 5AE2A 1QLUA 3S1EA 2QPMA 1V97A 3PQBA 2R8DA 1WYGA 1ZR6A 3I99A 1F0XA 2IPIA 3JS8A 3RJ8A 3NVWB 2VAOA 3AM9A 4JB1A 3VTEA 3W8ZA 3FWAA 4PVKA 1AHZA 2BVGA 3NRZB 4BC9A 1W1OA 3FW9A 4JAYA 2VFRA 1FO4A 3NVYB 3SR6B 3TX1A 4PWBA 3S1FA 1W1JA 1RM6B 1ZXIC 3FW7A 5G5GB 3NS1B 2Q4WA 4PVEA 2P4PA 1DIIA 2W3SA 5AE3A 3NVVB 1N61C 2W54A 1QLTA 2PLIA 2UUVA 1N62C 2R2ZA 3NVZB 3D2JA 2Y3SA 3S1DA 4PWCA 2Y08A 2VFVA 5HMRA 2UUUA 2I0KA 3DQ0A 2QKNA 1W1RA 3AMZA 1AHUA 1T3QC 3HSUA 5L6FA 4DNSA 2VFSA 5I1WA 1UXYA 1E0YA 1E8HA 2BVHA 2WDWA 3EUB3 2Y4GA 1AHVA 5ADZA 2EXRA 4BC7A 4MLAA 1HSKA 5L6GA 5FXPA 2E3TA 3ETRB 5D79A 2AXRA 2P3HA 5I1VA 2P13A 2GQTA 3AN1A 5HHZA 3PM9A 1DZNA 2VFUA 1WVEA 3S1CA 5FXFA 1SB3B 1W1KA 4XLOA 1W1QA 1VDVA 1I19A 2Y3RA 5FXDA 3LAEA 1DIQA 1FFVC 1N60C 2GQUA 3D2HA 4O95A 2O3GA 5G5HB 4ML8A 4EC3A 1N5XA 5K8EA 5HQXA 5AE1A 1N5WC 1W1LA 3KJMA 4HG0A 3TSJA 3B9JB 1FIQB 1W1MA 2MBRA 3FW8A 3W8XA 4PYTA 2YVSA 4PZFA 3HRDC 2NQWA 1MBTA 1E8GA 3DEDA 3GSYA 3POPA 2VFTA 1MBBA 1E8FA 2OAIA 1JRPA 2W3RA 3D2DA 4OALA 1W1SA 4BBYA 2RK5A 1WVFA 4PVHA 1JROA 2Q85A 3C0PA 3BW7A 2PLSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TSJ A;  5L6G A;  3TSH A;  2UUV A;  2BVF A;  3D2J A;  2Y3S A;  4UD8 A;  4PVJ A;  5D79 A;  5AWV A;  2AXR A;  4PWC A;  2Y08 A;  3RJA A;  3W8W A;  2UUU A;  5I1V A;  4EC3 A;  3FW8 A;  3PQB A;  3W8X A;  3HSU A;  1ZR6 A;  5L6F A;  4PZF A;  2IPI A;  3RJ8 A;  4DNS A;  3VTE A;  3W8Z A;  3FWA A;  4PVK A;  4XLO A;  2BVG A;  3GSY A;  3POP A;  3FW9 A;  2Y3R A;  5I1W A;  3D2D A;  2WDW A;  2BVH A;  3D2H A;  4PWB A;  2Y4G A;  3FW7 A;  4PVH A;  5K8E A;  4PVE A; 
#chains in the Genus database with same CATH topology
 1FFU C;  5FXE A;  1VAO A;  3TSH A;  1N63 C;  4ZOH B;  2W55 A;  2BVF A;  3LLB A;  4UD8 A;  4PVJ A;  5AWV A;  4BCA A;  3RJA A;  3W8W A;  5AE2 A;  1QLU A;  3S1E A;  2QPM A;  1V97 A;  3PQB A;  2R8D A;  1WYG A;  1ZR6 A;  3I99 A;  1F0X A;  2IPI A;  3JS8 A;  3RJ8 A;  3NVW B;  2VAO A;  3AM9 A;  4JB1 A;  3VTE A;  3W8Z A;  3FWA A;  4PVK A;  1AHZ A;  2BVG A;  3NRZ B;  4BC9 A;  1W1O A;  3FW9 A;  4JAY A;  2VFR A;  1FO4 A;  3NVY B;  3SR6 B;  3TX1 A;  4PWB A;  3S1F A;  1W1J A;  1RM6 B;  1ZXI C;  3FW7 A;  5G5G B;  3NS1 B;  2Q4W A;  4PVE A;  2P4P A;  1DII A;  2W3S A;  5AE3 A;  3NVV B;  1N61 C;  2W54 A;  1QLT A;  2PLI A;  2UUV A;  1N62 C;  2R2Z A;  3NVZ B;  3D2J A;  2Y3S A;  3S1D A;  4PWC A;  2Y08 A;  2VFV A;  5HMR A;  2UUU A;  2I0K A;  3DQ0 A;  2QKN A;  1W1R A;  3AMZ A;  1AHU A;  1T3Q C;  3HSU A;  5L6F A;  4DNS A;  2VFS A;  5I1W A;  1UXY A;  1E0Y A;  1E8H A;  2BVH A;  2WDW A;  3EUB 3;  2Y4G A;  1AHV A;  5ADZ A;  2EXR A;  4BC7 A;  4MLA A;  1HSK A;  5L6G A;  5FXP A;  2E3T A;  3ETR B;  5D79 A;  2AXR A;  2P3H A;  5I1V A;  2P13 A;  2GQT A;  3AN1 A;  5HHZ A;  3PM9 A;  1DZN A;  2VFU A;  1WVE A;  3S1C A;  5FXF A;  1SB3 B;  1W1K A;  4XLO A;  1W1Q A;  1VDV A;  1I19 A;  2Y3R A;  5FXD A;  3LAE A;  1DIQ A;  1FFV C;  1N60 C;  2GQU A;  3D2H A;  4O95 A;  2O3G A;  5G5H B;  4ML8 A;  4EC3 A;  1N5X A;  5K8E A;  5HQX A;  5AE1 A;  1N5W C;  1W1L A;  3KJM A;  4HG0 A;  3TSJ A;  3B9J B;  1FIQ B;  1W1M A;  2MBR A;  3FW8 A;  3W8X A;  4PYT A;  2YVS A;  4PZF A;  3HRD C;  2NQW A;  1MBT A;  1E8G A;  3DED A;  3GSY A;  3POP A;  2VFT A;  1MBB A;  1E8F A;  2OAI A;  1JRP A;  2W3R A;  3D2D A;  4OAL A;  1W1S A;  4BBY A;  2RK5 A;  1WVF A;  4PVH A;  1JRO A;  2Q85 A;  3C0P A;  3BW7 A;  2PLS A; 
#chains in the Genus database with same CATH homology
 1FFU C;  5FXE A;  1VAO A;  3TSH A;  1N63 C;  4ZOH B;  2W55 A;  2BVF A;  3LLB A;  4UD8 A;  4PVJ A;  5AWV A;  4BCA A;  3RJA A;  3W8W A;  5AE2 A;  1QLU A;  3S1E A;  2QPM A;  1V97 A;  3PQB A;  2R8D A;  1WYG A;  1ZR6 A;  3I99 A;  1F0X A;  2IPI A;  3JS8 A;  3RJ8 A;  3NVW B;  2VAO A;  3AM9 A;  4JB1 A;  3VTE A;  3W8Z A;  3FWA A;  4PVK A;  1AHZ A;  2BVG A;  3NRZ B;  4BC9 A;  1W1O A;  3FW9 A;  4JAY A;  2VFR A;  1FO4 A;  3NVY B;  3SR6 B;  3TX1 A;  4PWB A;  3S1F A;  1W1J A;  1RM6 B;  1ZXI C;  3FW7 A;  5G5G B;  3NS1 B;  2Q4W A;  4PVE A;  2P4P A;  1DII A;  2W3S A;  5AE3 A;  3NVV B;  1N61 C;  2W54 A;  1QLT A;  2PLI A;  2UUV A;  1N62 C;  2R2Z A;  3NVZ B;  3D2J A;  2Y3S A;  3S1D A;  4PWC A;  2Y08 A;  2VFV A;  5HMR A;  2UUU A;  2I0K A;  3DQ0 A;  2QKN A;  1W1R A;  3AMZ A;  1AHU A;  1T3Q C;  3HSU A;  5L6F A;  4DNS A;  2VFS A;  5I1W A;  1UXY A;  1E0Y A;  1E8H A;  2BVH A;  2WDW A;  3EUB 3;  2Y4G A;  1AHV A;  5ADZ A;  2EXR A;  4BC7 A;  4MLA A;  1HSK A;  5L6G A;  5FXP A;  2E3T A;  3ETR B;  5D79 A;  2AXR A;  2P3H A;  5I1V A;  2P13 A;  2GQT A;  3AN1 A;  5HHZ A;  3PM9 A;  1DZN A;  2VFU A;  1WVE A;  3S1C A;  5FXF A;  1SB3 B;  1W1K A;  4XLO A;  1W1Q A;  1VDV A;  1I19 A;  2Y3R A;  5FXD A;  3LAE A;  1DIQ A;  1FFV C;  1N60 C;  2GQU A;  3D2H A;  4O95 A;  2O3G A;  5G5H B;  4ML8 A;  4EC3 A;  1N5X A;  5K8E A;  5HQX A;  5AE1 A;  1N5W C;  1W1L A;  3KJM A;  4HG0 A;  3TSJ A;  3B9J B;  1FIQ B;  1W1M A;  2MBR A;  3FW8 A;  3W8X A;  4PYT A;  2YVS A;  4PZF A;  3HRD C;  2NQW A;  1MBT A;  1E8G A;  3DED A;  3GSY A;  3POP A;  2VFT A;  1MBB A;  1E8F A;  2OAI A;  1JRP A;  2W3R A;  3D2D A;  4OAL A;  1W1S A;  4BBY A;  2RK5 A;  1WVF A;  4PVH A;  1JRO A;  2Q85 A;  3C0P A;  3BW7 A;  2PLS A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...