3VTE | Genus

Total Genus 159

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	159
sequence length	518
structure length	502
Chain Sequence	ANPRENFLKCFSKHIPNPKLVYTQHDQLYMSILNSTIQNLRFISDTTPKPLVIVTPSNNSHIQATILCSKKVGLQIRTRSGGHDAEGMSYISQVPFVVVDLRNMHSIKIDVHSQTAWVEAGATLGEVYYWINEKNENLSFPGGYCPTVGVGGHFSGGGYGALMRNYGLAADNIIDAHLVNVDGKVLDRKSMGEDLFWAIRGGGGENFGIIAAWKIKLVAVPSKSTIFSVKKNMEIHGLVKLFNKWQNIAYKYDKDLVLMTHFITKNITTTVHGYFSSIFHGGVDSLVDLMNKSFPELGIKKTDCKEFSWIDTTIFYSGVVNFKKEILLDRSAGKKTAFSIKLDYVKKPIPETAMVKILEKLYEEDVGAGMYVLYPYGGIMEEISESAIPFPHRAGIMYELWYTASWEKQEDNEKHINWVRSVYNFTTPYVSQNPRLAYLNYRDLDLGKTNHASPNNYTQARIWGEKYFGKNFNRLVKVKTKVDPNNFFRNEQSIPPLPPHHH

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Oxidoreductase
source organism	Cannabis sativa
publication title	Structure and function of 1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa pubmed doi rcsb
molecule keywords	Tetrahydrocannabinolic acid synthase
total genus	159
structure length	502
sequence length	518
ec nomenclature	ec 1.21.3.7: Tetrahydrocannabinolic acid synthase.
pdb deposition date	2012-05-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01565	FAD_binding_4	FAD binding domain
A	PF08031	BBE	Berberine and berberine like

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.43.10	Alpha Beta	2-Layer Sandwich	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2	3vteA01
3.30.465.50	Alpha Beta	2-Layer Sandwich	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3	3vteA02
3.40.462.20	Alpha Beta	3-Layer(aba) Sandwich	Vanillyl-alcohol Oxidase; Chain A, domain 3	Vanillyl-alcohol Oxidase; Chain A, domain 3	3vteA03

1MBBA 1JROA 5D79A 1W1QA 2W3SA 4OALA 1W1LA 4ZOHB 4XLOA 1W1SA 2W3RA 3D2DA 3HSUA 1W1JA 2Y4GA 4PVJA 3NRZB 3W8WA 2W55A 2GQTA 3D2JA 3RJAA 1DIIA 1N5WC 3AN1A 1FIQB 1N63C 5HHZA 1AHZA 1I19A 5AE1A 1F0XA 2MBRA 3W8XA 2BVHA 2Q85A 3POPA 4JAYA 3FW9A 1DZNA 2BVFA 1DIQA 2GQUA 3AMZA 3RJ8A 2E3TA 3FW7A 1FFVC 1WVFA 3S1CA 1UXYA 4UD8A 5L6GA 5K8EA 3TSHA 1W1OA 2Q4WA 4PZFA 4DNSA 3S1DA 4PVKA 3B9JB 1AHVA 3S1EA 4BCAA 3KJMA 2AXRA 4O95A 3PQBA 2QPMA 2VFSA 1MBTA 1FO4A 3S1FA 4PYTA 1T3QC 4BC7A 1WYGA 4PVEA 1AHUA 4PWCA 1E0YA 3FWAA 3NS1B 3NVZB 1E8HA 2VFVA 5FXPA 1QLTA 5ADZA 3GSYA 2VAOA 4ML8A 1N5XA 3PM9A 4EC3A 3TSJA 1WVEA 4MLAA 2Y3SA 1VDVA 3I99A 3SR6B 5FXEA 3TX1A 5AWVA 1W1KA 3D2HA 3JS8A 1E8GA 5AE2A 4PVHA 2VFUA 5L6FA 5I1WA 3W8ZA 1N60C 1V97A 2IPIA 1N62C 2WDWA 5I1VA 1ZXIC 1E8FA 5FXFA 3ETRB 1ZR6A 2Y08A 4JB1A 1HSKA 5AE3A 1W1MA 1FFUC 3AM9A 2Y3RA 3C0PA 3EUB3 1N61C 2W54A 3BW7A 4PWBA 5FXDA 2VFTA 2BVGA 3VTEA 5HQXA 4BBYA 2VFRA 2QKNA 5HMRA 1VAOA 2EXRA 4BC9A 3FW8A 3DQ0A 1W1RA 1QLUA 2I0KA
chains in the Genus database with same CATH superfamily

1MBBA 1JROA 5D79A 1W1QA 3HRDC 2W3SA 4OALA 1W1LA 4ZOHB 4XLOA 1W1SA 2W3RA 3D2DA 3HSUA 1W1JA 2Y4GA 4PVJA 3NRZB 3W8WA 3NVYB 2W55A 2GQTA 3D2JA 3RJAA 1DIIA 1N5WC 3AN1A 1FIQB 1N63C 5HHZA 3EJBB 2P3HA 2P4PA 1AHZA 1I19A 5AE1A 1SB3B 1F0XA 2MBRA 3W8XA 2BVHA 2Q85A 3POPA 4JAYA 3FW9A 1DZNA 2BVFA 1DIQA 2GQUA 3AMZA 3RJ8A 2E3TA 1RM6B 3FW7A 1FFVC 1WVFA 3S1CA 1UXYA 4UD8A 5L6GA 5K8EA 3TSHA 1W1OA 2YVSA 4HG0A 2Q4WA 4PZFA 4DNSA 3S1DA 2UUVA 4PVKA 3B9JB 1AHVA 3S1EA 4BCAA 3KJMA 2AXRA 4O95A 3PQBA 2QPMA 2NQWA 2VFSA 2P13A 1MBTA 1FO4A 3S1FA 4PYTA 3NVVB 1T3QC 2OAIA 4BC7A 1WYGA 4PVEA 1AHUA 4PWCA 1E0YA 3FWAA 3NS1B 3NVZB 3LLBA 1E8HA 2VFVA 5FXPA 1QLTA 5ADZA 3GSYA 2VAOA 4ML8A 1N5XA 3PM9A 4EC3A 3TSJA 1WVEA 4MLAA 2Y3SA 1VDVA 3I99A 3SR6B 5FXEA 3TX1A 5AWVA 1W1KA 3D2HA 3JS8A 1E8GA 5AE2A 4PVHA 2PLIA 2VFUA 2R2ZA 2O3GA 5L6FA 5I1WA 3W8ZA 1N60C 1V97A 2IPIA 1N62C 2WDWA 5I1VA 1ZXIC 1E8FA 5FXFA 3ETRB 1ZR6A 2UUUA 2Y08A 4JB1A 1HSKA 5AE3A 5G5HB 1W1MA 1FFUC 3AM9A 2Y3RA 3EJDB 3EJEB 3C0PA 3NVWB 3EUB3 1N61C 2W54A 3BW7A 4PWBA 5FXDA 2VFTA 2BVGA 3VTEA 5HQXA 4BBYA 2VFRA 5G5GB 1JRPA 2RK5A 2QKNA 5HMRA 1VAOA 3LAEA 2EXRA 4BC9A 3FW8A 3DQ0A 1W1RA 1QLUA 3DEDA 2I0KA 2R8DA 2PLSA
chains in the Genus database with same CATH topology

1MBBA 1JROA 5D79A 1W1QA 3HRDC 2W3SA 4OALA 1W1LA 4ZOHB 4XLOA 1W1SA 2W3RA 3D2DA 3HSUA 1W1JA 2Y4GA 4PVJA 3NRZB 3W8WA 3NVYB 2W55A 2GQTA 3D2JA 3RJAA 1DIIA 1N5WC 3AN1A 1FIQB 1N63C 5HHZA 2P3HA 2P4PA 1AHZA 1I19A 5AE1A 1SB3B 1F0XA 2MBRA 3W8XA 2BVHA 2Q85A 3POPA 4JAYA 3FW9A 1DZNA 2BVFA 1DIQA 2GQUA 3AMZA 3RJ8A 2E3TA 1RM6B 3FW7A 1FFVC 1WVFA 3S1CA 1UXYA 4UD8A 5L6GA 5K8EA 3TSHA 1W1OA 2YVSA 4HG0A 2Q4WA 4PZFA 4DNSA 3S1DA 2UUVA 4PVKA 3B9JB 1AHVA 3S1EA 4BCAA 3KJMA 2AXRA 4O95A 3PQBA 2QPMA 2NQWA 2VFSA 2P13A 1MBTA 1FO4A 3S1FA 4PYTA 3NVVB 1T3QC 2OAIA 4BC7A 1WYGA 4PVEA 1AHUA 4PWCA 1E0YA 3FWAA 3NS1B 3NVZB 3LLBA 1E8HA 2VFVA 5FXPA 1QLTA 5ADZA 3GSYA 2VAOA 4ML8A 1N5XA 3PM9A 4EC3A 3TSJA 1WVEA 4MLAA 2Y3SA 1VDVA 3I99A 3SR6B 5FXEA 3TX1A 5AWVA 1W1KA 3D2HA 3JS8A 1E8GA 5AE2A 4PVHA 2PLIA 2VFUA 2R2ZA 2O3GA 5L6FA 5I1WA 3W8ZA 1N60C 1V97A 2IPIA 1N62C 2WDWA 5I1VA 1ZXIC 1E8FA 5FXFA 3ETRB 1ZR6A 2UUUA 2Y08A 4JB1A 1HSKA 5AE3A 5G5HB 1W1MA 1FFUC 3AM9A 2Y3RA 3C0PA 3NVWB 3EUB3 1N61C 2W54A 3BW7A 4PWBA 5FXDA 2VFTA 2BVGA 3VTEA 5HQXA 4BBYA 2VFRA 5G5GB 1JRPA 2RK5A 2QKNA 5HMRA 1VAOA 3LAEA 2EXRA 4BC9A 3FW8A 3DQ0A 1W1RA 1QLUA 3DEDA 2I0KA 2R8DA 2PLSA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1MBB A;  1JRO A;  5D79 A;  1W1Q A;  2W3S A;  4OAL A;  1W1L A;  4ZOH B;  4XLO A;  1W1S A;  2W3R A;  3D2D A;  3HSU A;  1W1J A;  2Y4G A;  4PVJ A;  3NRZ B;  3W8W A;  2W55 A;  2GQT A;  3D2J A;  3RJA A;  1DII A;  1N5W C;  3AN1 A;  1FIQ B;  1N63 C;  5HHZ A;  1AHZ A;  1I19 A;  5AE1 A;  1F0X A;  2MBR A;  3W8X A;  2BVH A;  2Q85 A;  3POP A;  4JAY A;  3FW9 A;  1DZN A;  2BVF A;  1DIQ A;  2GQU A;  3AMZ A;  3RJ8 A;  2E3T A;  3FW7 A;  1FFV C;  1WVF A;  3S1C A;  1UXY A;  4UD8 A;  5L6G A;  5K8E A;  3TSH A;  1W1O A;  2Q4W A;  4PZF A;  4DNS A;  3S1D A;  4PVK A;  3B9J B;  1AHV A;  3S1E A;  4BCA A;  3KJM A;  2AXR A;  4O95 A;  3PQB A;  2QPM A;  2VFS A;  1MBT A;  1FO4 A;  3S1F A;  4PYT A;  1T3Q C;  4BC7 A;  1WYG A;  4PVE A;  1AHU A;  4PWC A;  1E0Y A;  3FWA A;  3NS1 B;  3NVZ B;  1E8H A;  2VFV A;  5FXP A;  1QLT A;  5ADZ A;  3GSY A;  2VAO A;  4ML8 A;  1N5X A;  3PM9 A;  4EC3 A;  3TSJ A;  1WVE A;  4MLA A;  2Y3S A;  1VDV A;  3I99 A;  3SR6 B;  5FXE A;  3TX1 A;  5AWV A;  1W1K A;  3D2H A;  3JS8 A;  1E8G A;  5AE2 A;  4PVH A;  2VFU A;  5L6F A;  5I1W A;  3W8Z A;  1N60 C;  1V97 A;  2IPI A;  1N62 C;  2WDW A;  5I1V A;  1ZXI C;  1E8F A;  5FXF A;  3ETR B;  1ZR6 A;  2Y08 A;  4JB1 A;  1HSK A;  5AE3 A;  1W1M A;  1FFU C;  3AM9 A;  2Y3R A;  3C0P A;  3EUB 3;  1N61 C;  2W54 A;  3BW7 A;  4PWB A;  5FXD A;  2VFT A;  2BVG A;  3VTE A;  5HQX A;  4BBY A;  2VFR A;  2QKN A;  5HMR A;  1VAO A;  2EXR A;  4BC9 A;  3FW8 A;  3DQ0 A;  1W1R A;  1QLU A;  2I0K A; 
#chains in the Genus database with same CATH topology
 1MBB A;  1JRO A;  5D79 A;  1W1Q A;  3HRD C;  2W3S A;  4OAL A;  1W1L A;  4ZOH B;  4XLO A;  1W1S A;  2W3R A;  3D2D A;  3HSU A;  1W1J A;  2Y4G A;  4PVJ A;  3NRZ B;  3W8W A;  3NVY B;  2W55 A;  2GQT A;  3D2J A;  3RJA A;  1DII A;  1N5W C;  3AN1 A;  1FIQ B;  1N63 C;  5HHZ A;  3EJB B;  2P3H A;  2P4P A;  1AHZ A;  1I19 A;  5AE1 A;  1SB3 B;  1F0X A;  2MBR A;  3W8X A;  2BVH A;  2Q85 A;  3POP A;  4JAY A;  3FW9 A;  1DZN A;  2BVF A;  1DIQ A;  2GQU A;  3AMZ A;  3RJ8 A;  2E3T A;  1RM6 B;  3FW7 A;  1FFV C;  1WVF A;  3S1C A;  1UXY A;  4UD8 A;  5L6G A;  5K8E A;  3TSH A;  1W1O A;  2YVS A;  4HG0 A;  2Q4W A;  4PZF A;  4DNS A;  3S1D A;  2UUV A;  4PVK A;  3B9J B;  1AHV A;  3S1E A;  4BCA A;  3KJM A;  2AXR A;  4O95 A;  3PQB A;  2QPM A;  2NQW A;  2VFS A;  2P13 A;  1MBT A;  1FO4 A;  3S1F A;  4PYT A;  3NVV B;  1T3Q C;  2OAI A;  4BC7 A;  1WYG A;  4PVE A;  1AHU A;  4PWC A;  1E0Y A;  3FWA A;  3NS1 B;  3NVZ B;  3LLB A;  1E8H A;  2VFV A;  5FXP A;  1QLT A;  5ADZ A;  3GSY A;  2VAO A;  4ML8 A;  1N5X A;  3PM9 A;  4EC3 A;  3TSJ A;  1WVE A;  4MLA A;  2Y3S A;  1VDV A;  3I99 A;  3SR6 B;  5FXE A;  3TX1 A;  5AWV A;  1W1K A;  3D2H A;  3JS8 A;  1E8G A;  5AE2 A;  4PVH A;  2PLI A;  2VFU A;  2R2Z A;  2O3G A;  5L6F A;  5I1W A;  3W8Z A;  1N60 C;  1V97 A;  2IPI A;  1N62 C;  2WDW A;  5I1V A;  1ZXI C;  1E8F A;  5FXF A;  3ETR B;  1ZR6 A;  2UUU A;  2Y08 A;  4JB1 A;  1HSK A;  5AE3 A;  5G5H B;  1W1M A;  1FFU C;  3AM9 A;  2Y3R A;  3EJD B;  3EJE B;  3C0P A;  3NVW B;  3EUB 3;  1N61 C;  2W54 A;  3BW7 A;  4PWB A;  5FXD A;  2VFT A;  2BVG A;  3VTE A;  5HQX A;  4BBY A;  2VFR A;  5G5G B;  1JRP A;  2RK5 A;  2QKN A;  5HMR A;  1VAO A;  3LAE A;  2EXR A;  4BC9 A;  3FW8 A;  3DQ0 A;  1W1R A;  1QLU A;  3DED A;  2I0K A;  2R8D A;  2PLS A; 
#chains in the Genus database with same CATH homology
 1MBB A;  1JRO A;  5D79 A;  1W1Q A;  3HRD C;  2W3S A;  4OAL A;  1W1L A;  4ZOH B;  4XLO A;  1W1S A;  2W3R A;  3D2D A;  3HSU A;  1W1J A;  2Y4G A;  4PVJ A;  3NRZ B;  3W8W A;  3NVY B;  2W55 A;  2GQT A;  3D2J A;  3RJA A;  1DII A;  1N5W C;  3AN1 A;  1FIQ B;  1N63 C;  5HHZ A;  2P3H A;  2P4P A;  1AHZ A;  1I19 A;  5AE1 A;  1SB3 B;  1F0X A;  2MBR A;  3W8X A;  2BVH A;  2Q85 A;  3POP A;  4JAY A;  3FW9 A;  1DZN A;  2BVF A;  1DIQ A;  2GQU A;  3AMZ A;  3RJ8 A;  2E3T A;  1RM6 B;  3FW7 A;  1FFV C;  1WVF A;  3S1C A;  1UXY A;  4UD8 A;  5L6G A;  5K8E A;  3TSH A;  1W1O A;  2YVS A;  4HG0 A;  2Q4W A;  4PZF A;  4DNS A;  3S1D A;  2UUV A;  4PVK A;  3B9J B;  1AHV A;  3S1E A;  4BCA A;  3KJM A;  2AXR A;  4O95 A;  3PQB A;  2QPM A;  2NQW A;  2VFS A;  2P13 A;  1MBT A;  1FO4 A;  3S1F A;  4PYT A;  3NVV B;  1T3Q C;  2OAI A;  4BC7 A;  1WYG A;  4PVE A;  1AHU A;  4PWC A;  1E0Y A;  3FWA A;  3NS1 B;  3NVZ B;  3LLB A;  1E8H A;  2VFV A;  5FXP A;  1QLT A;  5ADZ A;  3GSY A;  2VAO A;  4ML8 A;  1N5X A;  3PM9 A;  4EC3 A;  3TSJ A;  1WVE A;  4MLA A;  2Y3S A;  1VDV A;  3I99 A;  3SR6 B;  5FXE A;  3TX1 A;  5AWV A;  1W1K A;  3D2H A;  3JS8 A;  1E8G A;  5AE2 A;  4PVH A;  2PLI A;  2VFU A;  2R2Z A;  2O3G A;  5L6F A;  5I1W A;  3W8Z A;  1N60 C;  1V97 A;  2IPI A;  1N62 C;  2WDW A;  5I1V A;  1ZXI C;  1E8F A;  5FXF A;  3ETR B;  1ZR6 A;  2UUU A;  2Y08 A;  4JB1 A;  1HSK A;  5AE3 A;  5G5H B;  1W1M A;  1FFU C;  3AM9 A;  2Y3R A;  3C0P A;  3NVW B;  3EUB 3;  1N61 C;  2W54 A;  3BW7 A;  4PWB A;  5FXD A;  2VFT A;  2BVG A;  3VTE A;  5HQX A;  4BBY A;  2VFR A;  5G5G B;  1JRP A;  2RK5 A;  2QKN A;  5HMR A;  1VAO A;  3LAE A;  2EXR A;  4BC9 A;  3FW8 A;  3DQ0 A;  1W1R A;  1QLU A;  3DED A;  2I0K A;  2R8D A;  2PLS A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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3VTEA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations