3W8XA

The complex structure of encm with trifluorotriketide
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
461
structure length
461
Chain Sequence
QFPQLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARCTSTPDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIKVSRRLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFGWLSRKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVVTAFEFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLRLAPPLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKATLPYRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPFTQLELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWAREGYRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTNLFRLNQNIPPS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Streptomyces maritimus
molecule keywords Putative FAD-dependent oxygenase EncM
total genus 137
structure length 461
sequence length 461
chains with identical sequence B
ec nomenclature ec 1.13.12.-:
pdb deposition date 2013-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3w8xA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3w8xA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3w8xA03
1WVFA 1WVEA 2P4PA 5K8EA 1W1SA 1E8HA 1T3QC 1FIQB 3FWAA 4PVHA 2PLIA 3GSYA 3TX1A 1WYGA 2Q4WA 2W3RA 2Y3RA 1FFUC 1AHVA 1MBTA 2NQWA 1N5WC 3LLBA 3ETRB 4DNSA 4PWBA 2MBRA 4ML8A 3NVWB 5FXFA 3W8ZA 5AE1A 3LAEA 2YVSA 1E8FA 1QLUA 4PYTA 4PVEA 5FXPA 1DIIA 1VAOA 3FW7A 3EUB3 4PVJA 3PQBA 2W55A 4PZFA 3RJAA 5L6GA 2QPMA 2PLSA 2QKNA 1W1QA 3DQ0A 4HG0A 2WDWA 5ADZA 2VAOA 3FW9A 5G5GB 2OAIA 5FXEA 2R8DA 3W8WA 3DEDA 1W1LA 2P13A 2GQTA 2BVHA 1RM6B 1FO4A 1N62C 1VDVA 2VFTA 4O95A 1N5XA 1ZXIC 3HRDC 5D79A 3D2DA 5I1VA 3BW7A 3NRZB 1FFVC 1JROA 5AE3A 4XLOA 5AWVA 1W1JA 4OALA 5HMRA 3AN1A 2AXRA 2RK5A 1W1MA 1N61C 5HHZA 3D2HA 2Q85A 2W3SA 4BCAA 3KJMA 3JS8A 2R2ZA 5HQXA 4PWCA 3TSHA 1AHUA 3NVVB 4JB1A 2Y4GA 3AMZA 1SB3B 5FXDA 4BC7A 3HSUA 1DZNA 4ZOHB 5G5HB 3AM9A 3S1DA 3RJ8A 3FW8A 1W1RA 2VFSA 5I1WA 3I99A 4UD8A 1N60C 1UXYA 3B9JB 3TSJA 4JAYA 2I0KA 1E0YA 2BVFA 2BVGA 4PVKA 5AE2A 2Y3SA 1E8GA 3SR6B 1HSKA 2E3TA 3S1FA 3S1CA 3W8XA 4BBYA 1DIQA 2O3GA 2IPIA 1F0XA 2VFVA 1QLTA 2VFUA 3PM9A 1V97A 2Y08A 3VTEA 3C0PA 2EXRA 3NVYB 1ZR6A 1W1OA 3NVZB 2W54A 3POPA 1JRPA 4MLAA 1W1KA 2GQUA 4BC9A 2VFRA 1MBBA 3D2JA 5L6FA 3NS1B 2P3HA 3S1EA 1AHZA 1I19A 1N63C 4EC3A
chains in the Genus database with same CATH superfamily
1WVFA 1WVEA 2P4PA 5K8EA 3EJBB 1W1SA 1E8HA 1T3QC 1FIQB 3FWAA 4PVHA 2PLIA 3GSYA 3TX1A 1WYGA 2Q4WA 2W3RA 2Y3RA 1FFUC 1AHVA 1MBTA 2NQWA 1N5WC 3LLBA 3ETRB 4DNSA 4PWBA 2MBRA 4ML8A 3NVWB 5FXFA 3W8ZA 5AE1A 3LAEA 2YVSA 1E8FA 1QLUA 4PYTA 4PVEA 5FXPA 1DIIA 1VAOA 3FW7A 3EUB3 4PVJA 3PQBA 2W55A 4PZFA 3RJAA 5L6GA 2QPMA 2PLSA 2QKNA 1W1QA 3DQ0A 4HG0A 2WDWA 5ADZA 2VAOA 3FW9A 5G5GB 2OAIA 5FXEA 2R8DA 3W8WA 3DEDA 1W1LA 2P13A 2GQTA 2BVHA 1RM6B 1FO4A 1N62C 1VDVA 2VFTA 4O95A 1N5XA 1ZXIC 3HRDC 5D79A 3D2DA 5I1VA 3BW7A 3NRZB 1FFVC 1JROA 5AE3A 4XLOA 2UUVA 1W1JA 5AWVA 4OALA 5HMRA 3AN1A 2UUUA 2AXRA 2RK5A 1W1MA 1N61C 5HHZA 3D2HA 2Q85A 2W3SA 4BCAA 3EJDB 3JS8A 3KJMA 2R2ZA 5HQXA 4PWCA 3TSHA 1AHUA 3NVVB 4JB1A 2Y4GA 3AMZA 1SB3B 5FXDA 4BC7A 3HSUA 1DZNA 4ZOHB 5G5HB 3EJEB 3AM9A 3S1DA 3RJ8A 3FW8A 1W1RA 2VFSA 5I1WA 3I99A 4UD8A 1N60C 1UXYA 3B9JB 3TSJA 4JAYA 2I0KA 1E0YA 2BVFA 2BVGA 4PVKA 5AE2A 2Y3SA 1E8GA 3SR6B 1HSKA 2E3TA 3S1FA 3S1CA 3W8XA 4BBYA 1DIQA 2IPIA 2O3GA 1F0XA 2VFVA 1QLTA 2VFUA 3PM9A 1V97A 2Y08A 3VTEA 3C0PA 2EXRA 3NVYB 1ZR6A 1W1OA 3NVZB 2W54A 3POPA 1JRPA 4MLAA 1W1KA 2GQUA 4BC9A 2VFRA 1MBBA 3D2JA 5L6FA 3NS1B 2P3HA 3S1EA 1AHZA 1I19A 1N63C 4EC3A
chains in the Genus database with same CATH topology
1WVFA 1WVEA 2P4PA 5K8EA 1W1SA 1E8HA 1T3QC 1FIQB 3FWAA 4PVHA 2PLIA 3GSYA 3TX1A 1WYGA 2Q4WA 2W3RA 2Y3RA 1FFUC 1AHVA 1MBTA 2NQWA 1N5WC 3LLBA 3ETRB 4DNSA 4PWBA 2MBRA 4ML8A 3NVWB 5FXFA 3W8ZA 5AE1A 3LAEA 2YVSA 1E8FA 1QLUA 4PYTA 4PVEA 5FXPA 1DIIA 1VAOA 3FW7A 3EUB3 4PVJA 3PQBA 2W55A 4PZFA 3RJAA 5L6GA 2QPMA 2PLSA 2QKNA 1W1QA 3DQ0A 4HG0A 2WDWA 5ADZA 2VAOA 3FW9A 5G5GB 2OAIA 5FXEA 2R8DA 3W8WA 3DEDA 1W1LA 2P13A 2GQTA 2BVHA 1RM6B 1FO4A 1N62C 1VDVA 2VFTA 4O95A 1N5XA 1ZXIC 3HRDC 5D79A 3D2DA 5I1VA 3BW7A 3NRZB 1FFVC 1JROA 5AE3A 4XLOA 2UUVA 1W1JA 5AWVA 4OALA 5HMRA 3AN1A 2UUUA 2AXRA 2RK5A 1W1MA 1N61C 5HHZA 3D2HA 2Q85A 2W3SA 4BCAA 3KJMA 3JS8A 2R2ZA 5HQXA 4PWCA 3TSHA 1AHUA 3NVVB 4JB1A 2Y4GA 3AMZA 1SB3B 5FXDA 4BC7A 3HSUA 1DZNA 4ZOHB 5G5HB 3AM9A 3S1DA 3RJ8A 3FW8A 1W1RA 2VFSA 5I1WA 3I99A 4UD8A 1N60C 1UXYA 3B9JB 3TSJA 4JAYA 2I0KA 1E0YA 2BVFA 2BVGA 4PVKA 5AE2A 2Y3SA 1E8GA 3SR6B 1HSKA 2E3TA 3S1FA 3S1CA 3W8XA 4BBYA 1DIQA 2IPIA 2O3GA 1F0XA 2VFVA 1QLTA 2VFUA 3PM9A 1V97A 2Y08A 3VTEA 3C0PA 2EXRA 3NVYB 1ZR6A 1W1OA 3NVZB 2W54A 3POPA 1JRPA 4MLAA 1W1KA 2GQUA 4BC9A 2VFRA 1MBBA 3D2JA 5L6FA 3NS1B 2P3HA 3S1EA 1AHZA 1I19A 1N63C 4EC3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WVF A;  1WVE A;  2P4P A;  5K8E A;  1W1S A;  1E8H A;  1T3Q C;  1FIQ B;  3FWA A;  4PVH A;  2PLI A;  3GSY A;  3TX1 A;  1WYG A;  2Q4W A;  2W3R A;  2Y3R A;  1FFU C;  1AHV A;  1MBT A;  2NQW A;  1N5W C;  3LLB A;  3ETR B;  4DNS A;  4PWB A;  2MBR A;  4ML8 A;  3NVW B;  5FXF A;  3W8Z A;  5AE1 A;  3LAE A;  2YVS A;  1E8F A;  1QLU A;  4PYT A;  4PVE A;  5FXP A;  1DII A;  1VAO A;  3FW7 A;  3EUB 3;  4PVJ A;  3PQB A;  2W55 A;  4PZF A;  3RJA A;  5L6G A;  2QPM A;  2PLS A;  2QKN A;  1W1Q A;  3DQ0 A;  4HG0 A;  2WDW A;  5ADZ A;  2VAO A;  3FW9 A;  5G5G B;  2OAI A;  5FXE A;  2R8D A;  3W8W A;  3DED A;  1W1L A;  2P13 A;  2GQT A;  2BVH A;  1RM6 B;  1FO4 A;  1N62 C;  1VDV A;  2VFT A;  4O95 A;  1N5X A;  1ZXI C;  3HRD C;  5D79 A;  3D2D A;  5I1V A;  3BW7 A;  3NRZ B;  1FFV C;  1JRO A;  5AE3 A;  4XLO A;  5AWV A;  1W1J A;  4OAL A;  5HMR A;  3AN1 A;  2AXR A;  2RK5 A;  1W1M A;  1N61 C;  5HHZ A;  3D2H A;  2Q85 A;  2W3S A;  4BCA A;  3KJM A;  3JS8 A;  2R2Z A;  5HQX A;  4PWC A;  3TSH A;  1AHU A;  3NVV B;  4JB1 A;  2Y4G A;  3AMZ A;  1SB3 B;  5FXD A;  4BC7 A;  3HSU A;  1DZN A;  4ZOH B;  5G5H B;  3AM9 A;  3S1D A;  3RJ8 A;  3FW8 A;  1W1R A;  2VFS A;  5I1W A;  3I99 A;  4UD8 A;  1N60 C;  1UXY A;  3B9J B;  3TSJ A;  4JAY A;  2I0K A;  1E0Y A;  2BVF A;  2BVG A;  4PVK A;  5AE2 A;  2Y3S A;  1E8G A;  3SR6 B;  1HSK A;  2E3T A;  3S1F A;  3S1C A;  3W8X A;  4BBY A;  1DIQ A;  2O3G A;  2IPI A;  1F0X A;  2VFV A;  1QLT A;  2VFU A;  3PM9 A;  1V97 A;  2Y08 A;  3VTE A;  3C0P A;  2EXR A;  3NVY B;  1ZR6 A;  1W1O A;  3NVZ B;  2W54 A;  3POP A;  1JRP A;  4MLA A;  1W1K A;  2GQU A;  4BC9 A;  2VFR A;  1MBB A;  3D2J A;  5L6F A;  3NS1 B;  2P3H A;  3S1E A;  1AHZ A;  1I19 A;  1N63 C;  4EC3 A; 
#chains in the Genus database with same CATH topology
 1WVF A;  1WVE A;  2P4P A;  5K8E A;  3EJB B;  1W1S A;  1E8H A;  1T3Q C;  1FIQ B;  3FWA A;  4PVH A;  2PLI A;  3GSY A;  3TX1 A;  1WYG A;  2Q4W A;  2W3R A;  2Y3R A;  1FFU C;  1AHV A;  1MBT A;  2NQW A;  1N5W C;  3LLB A;  3ETR B;  4DNS A;  4PWB A;  2MBR A;  4ML8 A;  3NVW B;  5FXF A;  3W8Z A;  5AE1 A;  3LAE A;  2YVS A;  1E8F A;  1QLU A;  4PYT A;  4PVE A;  5FXP A;  1DII A;  1VAO A;  3FW7 A;  3EUB 3;  4PVJ A;  3PQB A;  2W55 A;  4PZF A;  3RJA A;  5L6G A;  2QPM A;  2PLS A;  2QKN A;  1W1Q A;  3DQ0 A;  4HG0 A;  2WDW A;  5ADZ A;  2VAO A;  3FW9 A;  5G5G B;  2OAI A;  5FXE A;  2R8D A;  3W8W A;  3DED A;  1W1L A;  2P13 A;  2GQT A;  2BVH A;  1RM6 B;  1FO4 A;  1N62 C;  1VDV A;  2VFT A;  4O95 A;  1N5X A;  1ZXI C;  3HRD C;  5D79 A;  3D2D A;  5I1V A;  3BW7 A;  3NRZ B;  1FFV C;  1JRO A;  5AE3 A;  4XLO A;  2UUV A;  1W1J A;  5AWV A;  4OAL A;  5HMR A;  3AN1 A;  2UUU A;  2AXR A;  2RK5 A;  1W1M A;  1N61 C;  5HHZ A;  3D2H A;  2Q85 A;  2W3S A;  4BCA A;  3EJD B;  3JS8 A;  3KJM A;  2R2Z A;  5HQX A;  4PWC A;  3TSH A;  1AHU A;  3NVV B;  4JB1 A;  2Y4G A;  3AMZ A;  1SB3 B;  5FXD A;  4BC7 A;  3HSU A;  1DZN A;  4ZOH B;  5G5H B;  3EJE B;  3AM9 A;  3S1D A;  3RJ8 A;  3FW8 A;  1W1R A;  2VFS A;  5I1W A;  3I99 A;  4UD8 A;  1N60 C;  1UXY A;  3B9J B;  3TSJ A;  4JAY A;  2I0K A;  1E0Y A;  2BVF A;  2BVG A;  4PVK A;  5AE2 A;  2Y3S A;  1E8G A;  3SR6 B;  1HSK A;  2E3T A;  3S1F A;  3S1C A;  3W8X A;  4BBY A;  1DIQ A;  2IPI A;  2O3G A;  1F0X A;  2VFV A;  1QLT A;  2VFU A;  3PM9 A;  1V97 A;  2Y08 A;  3VTE A;  3C0P A;  2EXR A;  3NVY B;  1ZR6 A;  1W1O A;  3NVZ B;  2W54 A;  3POP A;  1JRP A;  4MLA A;  1W1K A;  2GQU A;  4BC9 A;  2VFR A;  1MBB A;  3D2J A;  5L6F A;  3NS1 B;  2P3H A;  3S1E A;  1AHZ A;  1I19 A;  1N63 C;  4EC3 A; 
#chains in the Genus database with same CATH homology
 1WVF A;  1WVE A;  2P4P A;  5K8E A;  1W1S A;  1E8H A;  1T3Q C;  1FIQ B;  3FWA A;  4PVH A;  2PLI A;  3GSY A;  3TX1 A;  1WYG A;  2Q4W A;  2W3R A;  2Y3R A;  1FFU C;  1AHV A;  1MBT A;  2NQW A;  1N5W C;  3LLB A;  3ETR B;  4DNS A;  4PWB A;  2MBR A;  4ML8 A;  3NVW B;  5FXF A;  3W8Z A;  5AE1 A;  3LAE A;  2YVS A;  1E8F A;  1QLU A;  4PYT A;  4PVE A;  5FXP A;  1DII A;  1VAO A;  3FW7 A;  3EUB 3;  4PVJ A;  3PQB A;  2W55 A;  4PZF A;  3RJA A;  5L6G A;  2QPM A;  2PLS A;  2QKN A;  1W1Q A;  3DQ0 A;  4HG0 A;  2WDW A;  5ADZ A;  2VAO A;  3FW9 A;  5G5G B;  2OAI A;  5FXE A;  2R8D A;  3W8W A;  3DED A;  1W1L A;  2P13 A;  2GQT A;  2BVH A;  1RM6 B;  1FO4 A;  1N62 C;  1VDV A;  2VFT A;  4O95 A;  1N5X A;  1ZXI C;  3HRD C;  5D79 A;  3D2D A;  5I1V A;  3BW7 A;  3NRZ B;  1FFV C;  1JRO A;  5AE3 A;  4XLO A;  2UUV A;  1W1J A;  5AWV A;  4OAL A;  5HMR A;  3AN1 A;  2UUU A;  2AXR A;  2RK5 A;  1W1M A;  1N61 C;  5HHZ A;  3D2H A;  2Q85 A;  2W3S A;  4BCA A;  3KJM A;  3JS8 A;  2R2Z A;  5HQX A;  4PWC A;  3TSH A;  1AHU A;  3NVV B;  4JB1 A;  2Y4G A;  3AMZ A;  1SB3 B;  5FXD A;  4BC7 A;  3HSU A;  1DZN A;  4ZOH B;  5G5H B;  3AM9 A;  3S1D A;  3RJ8 A;  3FW8 A;  1W1R A;  2VFS A;  5I1W A;  3I99 A;  4UD8 A;  1N60 C;  1UXY A;  3B9J B;  3TSJ A;  4JAY A;  2I0K A;  1E0Y A;  2BVF A;  2BVG A;  4PVK A;  5AE2 A;  2Y3S A;  1E8G A;  3SR6 B;  1HSK A;  2E3T A;  3S1F A;  3S1C A;  3W8X A;  4BBY A;  1DIQ A;  2IPI A;  2O3G A;  1F0X A;  2VFV A;  1QLT A;  2VFU A;  3PM9 A;  1V97 A;  2Y08 A;  3VTE A;  3C0P A;  2EXR A;  3NVY B;  1ZR6 A;  1W1O A;  3NVZ B;  2W54 A;  3POP A;  1JRP A;  4MLA A;  1W1K A;  2GQU A;  4BC9 A;  2VFR A;  1MBB A;  3D2J A;  5L6F A;  3NS1 B;  2P3H A;  3S1E A;  1AHZ A;  1I19 A;  1N63 C;  4EC3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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