3W8ZA

The complex structure of encm with hydroxytetraketide
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
460
structure length
460
Chain Sequence
QFPQLDPATLAAFSAAFRGELIWPSDADYDEARRIWNGTIDRRPALIARCTSTPDVVAAVSFARKSGLLVAVRGGGHSMAGHSVCDGGIVIDLSLMNSIKVSRRLRRARAQGGCLLGAFDTATQAHMLATPAGVVSHTGLGGLVLGGGFGWLSRKYGLSIDNLTSVEIVTADGGVLTASDTENPDLFWAVRGGGGNFGVVTAFEFDLHRVGPVRFASTYYSLDEGPQVIRAWRDHMATAPDELTWALYLRLAPPLPELPADMHGKPVICAMSCWIGDPHEGERQLESILHAGKPHGLTKATLPYRALQAYSFPGAVVPDRIYTKSGYLNELSDEATDTVLEHAADIASPFTQLELLYLGGAVARVPDDATAYPNRQSPFVTNLAAAWMDPTEDARHTAWAREGYRALAGHLSGGYVNFMNPGEADRTREAYGAAKFERLQGVKAKYDPTNLFRLNQNIPP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Streptomyces maritimus
molecule keywords Putative FAD-dependent oxygenase EncM
total genus 139
structure length 460
sequence length 460
chains with identical sequence B
ec nomenclature ec 1.13.12.-:
pdb deposition date 2013-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF08031 BBE Berberine and berberine like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 3w8zA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 3w8zA02
3.40.462.20 Alpha Beta 3-Layer(aba) Sandwich Vanillyl-alcohol Oxidase; Chain A, domain 3 Vanillyl-alcohol Oxidase; Chain A, domain 3 3w8zA03
4EC3A 2EXRA 3NVWB 2MBRA 1FFVC 2GQTA 2Y4GA 3ETRB 3EUB3 1W1QA 1ZR6A 2AXRA 1AHVA 2OAIA 3NVZB 1UXYA 2VFTA 4XLOA 4MLAA 5AE1A 1N5WC 2W55A 2VFRA 4PZFA 3FW7A 5D79A 3AM9A 5HMRA 3RJAA 5AE3A 3PQBA 3POPA 1AHUA 2IPIA 3AMZA 2P3HA 2Y3RA 2I0KA 3W8XA 4ML8A 1N63C 2Q4WA 1N60C 3W8WA 5G5HB 2VFSA 3S1FA 1DIQA 5G5GB 5FXPA 3D2JA 1V97A 2BVHA 1FFUC 4PVEA 1FIQB 3DQ0A 5FXDA 2R2ZA 1MBBA 2QPMA 3NVYB 2PLIA 4PVHA 3C0PA 1F0XA 4BC7A 1DIIA 4JAYA 1E8HA 1I19A 5L6GA 2RK5A 2GQUA 5K8EA 1W1JA 4UD8A 5FXEA 5FXFA 1RM6B 1QLUA 3NS1B 1JRPA 3NVVB 4OALA 2O3GA 5I1VA 1AHZA 3D2DA 4BCAA 4HG0A 4JB1A 1W1SA 4PWCA 1DZNA 3RJ8A 3AN1A 2QKNA 5ADZA 5L6FA 3FWAA 3FW9A 1W1OA 1W1MA 2W3SA 3TSHA 5HQXA 1W1KA 1ZXIC 3TX1A 4BBYA 2YVSA 4O95A 2BVFA 2Y3SA 1MBTA 1W1RA 1E0YA 2VFUA 1WVEA 1WVFA 2R8DA 3D2HA 3LLBA 1N5XA 1VDVA 3VTEA 3BW7A 1QLTA 1JROA 2PLSA 1E8FA 3PM9A 1N61C 2VFVA 3I99A 3S1EA 5I1WA 1HSKA 2W3RA 1WYGA 3FW8A 2P13A 2BVGA 3GSYA 3JS8A 4PVJA 1W1LA 2P4PA 2W54A 3LAEA 5HHZA 3W8ZA 4PWBA 1SB3B 2Q85A 3DEDA 3NRZB 3HSUA 3HRDC 2VAOA 1E8GA 3TSJA 3B9JB 1FO4A 3KJMA 3S1DA 2Y08A 2WDWA 4PVKA 5AWVA 4BC9A 3SR6B 2E3TA 1VAOA 4ZOHB 1T3QC 4PYTA 3S1CA 4DNSA 5AE2A 1N62C 2NQWA
chains in the Genus database with same CATH superfamily
3NVWB 2EXRA 4EC3A 2MBRA 1FFVC 2GQTA 2Y4GA 3ETRB 3EUB3 1W1QA 1ZR6A 2AXRA 1AHVA 2OAIA 3NVZB 1UXYA 2VFTA 4XLOA 4MLAA 5AE1A 1N5WC 2UUUA 2W55A 2VFRA 4PZFA 3FW7A 5D79A 3AM9A 3EJBB 5HMRA 3RJAA 5AE3A 3PQBA 3POPA 1AHUA 2IPIA 3AMZA 2P3HA 2Y3RA 2I0KA 3W8XA 4ML8A 1N63C 2Q4WA 1N60C 3W8WA 5G5HB 2VFSA 3S1FA 1DIQA 5G5GB 5FXPA 3D2JA 1V97A 2BVHA 1FFUC 4PVEA 1FIQB 3DQ0A 5FXDA 2R2ZA 1MBBA 2QPMA 3NVYB 2PLIA 4PVHA 3C0PA 1F0XA 4BC7A 1DIIA 4JAYA 1E8HA 1I19A 5L6GA 2RK5A 2GQUA 5K8EA 1W1JA 4UD8A 5FXEA 5FXFA 1RM6B 1QLUA 3NS1B 3NVVB 1JRPA 4OALA 2O3GA 5I1VA 1AHZA 3D2DA 4BCAA 4HG0A 4JB1A 1W1SA 4PWCA 1DZNA 3RJ8A 3AN1A 3EJDB 2QKNA 5ADZA 5L6FA 3FWAA 3FW9A 1W1OA 1W1MA 2W3SA 3TSHA 5HQXA 1W1KA 1ZXIC 3TX1A 4BBYA 2YVSA 4O95A 2BVFA 2Y3SA 1MBTA 1W1RA 1E0YA 2VFUA 1WVEA 1WVFA 2R8DA 3D2HA 3LLBA 1N5XA 1VDVA 3VTEA 3BW7A 1QLTA 1JROA 2UUVA 2PLSA 1E8FA 3PM9A 1N61C 2VFVA 3I99A 3S1EA 5I1WA 1HSKA 2W3RA 1WYGA 3FW8A 2P13A 2BVGA 3GSYA 3EJEB 3JS8A 4PVJA 1W1LA 2P4PA 2W54A 3LAEA 5HHZA 3W8ZA 4PWBA 1SB3B 2Q85A 3DEDA 3NRZB 3HSUA 3HRDC 2VAOA 1E8GA 3TSJA 3B9JB 1FO4A 3KJMA 3S1DA 2Y08A 2WDWA 4PVKA 5AWVA 4BC9A 3SR6B 2E3TA 1VAOA 4ZOHB 1T3QC 4PYTA 3S1CA 4DNSA 5AE2A 1N62C 2NQWA
chains in the Genus database with same CATH topology
4EC3A 2EXRA 3NVWB 2MBRA 1FFVC 2GQTA 2Y4GA 3ETRB 3EUB3 1W1QA 1ZR6A 2AXRA 1AHVA 2OAIA 3NVZB 1UXYA 2VFTA 4XLOA 4MLAA 5AE1A 1N5WC 2UUUA 2W55A 2VFRA 4PZFA 3FW7A 5D79A 3AM9A 5HMRA 3RJAA 5AE3A 3PQBA 3POPA 1AHUA 2IPIA 3AMZA 2P3HA 2Y3RA 2I0KA 3W8XA 4ML8A 1N63C 2Q4WA 1N60C 3W8WA 5G5HB 2VFSA 3S1FA 1DIQA 5G5GB 5FXPA 3D2JA 1V97A 2BVHA 1FFUC 4PVEA 1FIQB 3DQ0A 5FXDA 2R2ZA 1MBBA 2QPMA 3NVYB 2PLIA 4PVHA 3C0PA 1F0XA 4BC7A 1DIIA 4JAYA 1E8HA 1I19A 5L6GA 2RK5A 2GQUA 5K8EA 1W1JA 4UD8A 5FXEA 5FXFA 1RM6B 1QLUA 3NS1B 1JRPA 3NVVB 4OALA 2O3GA 5I1VA 1AHZA 3D2DA 4BCAA 4HG0A 4JB1A 1W1SA 4PWCA 1DZNA 3RJ8A 3AN1A 2QKNA 5ADZA 5L6FA 3FWAA 3FW9A 1W1OA 1W1MA 2W3SA 3TSHA 5HQXA 1W1KA 1ZXIC 3TX1A 4BBYA 2YVSA 4O95A 2BVFA 2Y3SA 1MBTA 1W1RA 1E0YA 2VFUA 1WVEA 1WVFA 2R8DA 3D2HA 3LLBA 1N5XA 1VDVA 3VTEA 3BW7A 1QLTA 1JROA 2UUVA 2PLSA 1E8FA 3PM9A 1N61C 2VFVA 3I99A 3S1EA 5I1WA 1HSKA 2W3RA 1WYGA 3FW8A 2P13A 2BVGA 3GSYA 3JS8A 4PVJA 1W1LA 2P4PA 2W54A 3LAEA 5HHZA 3W8ZA 4PWBA 1SB3B 2Q85A 3DEDA 3NRZB 3HSUA 3HRDC 2VAOA 1E8GA 3TSJA 3B9JB 1FO4A 3KJMA 3S1DA 2Y08A 2WDWA 4PVKA 5AWVA 4BC9A 3SR6B 2E3TA 1VAOA 4ZOHB 1T3QC 4PYTA 3S1CA 4DNSA 5AE2A 1N62C 2NQWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EC3 A;  2EXR A;  3NVW B;  2MBR A;  1FFV C;  2GQT A;  2Y4G A;  3ETR B;  3EUB 3;  1W1Q A;  1ZR6 A;  2AXR A;  1AHV A;  2OAI A;  3NVZ B;  1UXY A;  2VFT A;  4XLO A;  4MLA A;  5AE1 A;  1N5W C;  2W55 A;  2VFR A;  4PZF A;  3FW7 A;  5D79 A;  3AM9 A;  5HMR A;  3RJA A;  5AE3 A;  3PQB A;  3POP A;  1AHU A;  2IPI A;  3AMZ A;  2P3H A;  2Y3R A;  2I0K A;  3W8X A;  4ML8 A;  1N63 C;  2Q4W A;  1N60 C;  3W8W A;  5G5H B;  2VFS A;  3S1F A;  1DIQ A;  5G5G B;  5FXP A;  3D2J A;  1V97 A;  2BVH A;  1FFU C;  4PVE A;  1FIQ B;  3DQ0 A;  5FXD A;  2R2Z A;  1MBB A;  2QPM A;  3NVY B;  2PLI A;  4PVH A;  3C0P A;  1F0X A;  4BC7 A;  1DII A;  4JAY A;  1E8H A;  1I19 A;  5L6G A;  2RK5 A;  2GQU A;  5K8E A;  1W1J A;  4UD8 A;  5FXE A;  5FXF A;  1RM6 B;  1QLU A;  3NS1 B;  1JRP A;  3NVV B;  4OAL A;  2O3G A;  5I1V A;  1AHZ A;  3D2D A;  4BCA A;  4HG0 A;  4JB1 A;  1W1S A;  4PWC A;  1DZN A;  3RJ8 A;  3AN1 A;  2QKN A;  5ADZ A;  5L6F A;  3FWA A;  3FW9 A;  1W1O A;  1W1M A;  2W3S A;  3TSH A;  5HQX A;  1W1K A;  1ZXI C;  3TX1 A;  4BBY A;  2YVS A;  4O95 A;  2BVF A;  2Y3S A;  1MBT A;  1W1R A;  1E0Y A;  2VFU A;  1WVE A;  1WVF A;  2R8D A;  3D2H A;  3LLB A;  1N5X A;  1VDV A;  3VTE A;  3BW7 A;  1QLT A;  1JRO A;  2PLS A;  1E8F A;  3PM9 A;  1N61 C;  2VFV A;  3I99 A;  3S1E A;  5I1W A;  1HSK A;  2W3R A;  1WYG A;  3FW8 A;  2P13 A;  2BVG A;  3GSY A;  3JS8 A;  4PVJ A;  1W1L A;  2P4P A;  2W54 A;  3LAE A;  5HHZ A;  3W8Z A;  4PWB A;  1SB3 B;  2Q85 A;  3DED A;  3NRZ B;  3HSU A;  3HRD C;  2VAO A;  1E8G A;  3TSJ A;  3B9J B;  1FO4 A;  3KJM A;  3S1D A;  2Y08 A;  2WDW A;  4PVK A;  5AWV A;  4BC9 A;  3SR6 B;  2E3T A;  1VAO A;  4ZOH B;  1T3Q C;  4PYT A;  3S1C A;  4DNS A;  5AE2 A;  1N62 C;  2NQW A; 
#chains in the Genus database with same CATH topology
 3NVW B;  2EXR A;  4EC3 A;  2MBR A;  1FFV C;  2GQT A;  2Y4G A;  3ETR B;  3EUB 3;  1W1Q A;  1ZR6 A;  2AXR A;  1AHV A;  2OAI A;  3NVZ B;  1UXY A;  2VFT A;  4XLO A;  4MLA A;  5AE1 A;  1N5W C;  2UUU A;  2W55 A;  2VFR A;  4PZF A;  3FW7 A;  5D79 A;  3AM9 A;  3EJB B;  5HMR A;  3RJA A;  5AE3 A;  3PQB A;  3POP A;  1AHU A;  2IPI A;  3AMZ A;  2P3H A;  2Y3R A;  2I0K A;  3W8X A;  4ML8 A;  1N63 C;  2Q4W A;  1N60 C;  3W8W A;  5G5H B;  2VFS A;  3S1F A;  1DIQ A;  5G5G B;  5FXP A;  3D2J A;  1V97 A;  2BVH A;  1FFU C;  4PVE A;  1FIQ B;  3DQ0 A;  5FXD A;  2R2Z A;  1MBB A;  2QPM A;  3NVY B;  2PLI A;  4PVH A;  3C0P A;  1F0X A;  4BC7 A;  1DII A;  4JAY A;  1E8H A;  1I19 A;  5L6G A;  2RK5 A;  2GQU A;  5K8E A;  1W1J A;  4UD8 A;  5FXE A;  5FXF A;  1RM6 B;  1QLU A;  3NS1 B;  3NVV B;  1JRP A;  4OAL A;  2O3G A;  5I1V A;  1AHZ A;  3D2D A;  4BCA A;  4HG0 A;  4JB1 A;  1W1S A;  4PWC A;  1DZN A;  3RJ8 A;  3AN1 A;  3EJD B;  2QKN A;  5ADZ A;  5L6F A;  3FWA A;  3FW9 A;  1W1O A;  1W1M A;  2W3S A;  3TSH A;  5HQX A;  1W1K A;  1ZXI C;  3TX1 A;  4BBY A;  2YVS A;  4O95 A;  2BVF A;  2Y3S A;  1MBT A;  1W1R A;  1E0Y A;  2VFU A;  1WVE A;  1WVF A;  2R8D A;  3D2H A;  3LLB A;  1N5X A;  1VDV A;  3VTE A;  3BW7 A;  1QLT A;  1JRO A;  2UUV A;  2PLS A;  1E8F A;  3PM9 A;  1N61 C;  2VFV A;  3I99 A;  3S1E A;  5I1W A;  1HSK A;  2W3R A;  1WYG A;  3FW8 A;  2P13 A;  2BVG A;  3GSY A;  3EJE B;  3JS8 A;  4PVJ A;  1W1L A;  2P4P A;  2W54 A;  3LAE A;  5HHZ A;  3W8Z A;  4PWB A;  1SB3 B;  2Q85 A;  3DED A;  3NRZ B;  3HSU A;  3HRD C;  2VAO A;  1E8G A;  3TSJ A;  3B9J B;  1FO4 A;  3KJM A;  3S1D A;  2Y08 A;  2WDW A;  4PVK A;  5AWV A;  4BC9 A;  3SR6 B;  2E3T A;  1VAO A;  4ZOH B;  1T3Q C;  4PYT A;  3S1C A;  4DNS A;  5AE2 A;  1N62 C;  2NQW A; 
#chains in the Genus database with same CATH homology
 4EC3 A;  2EXR A;  3NVW B;  2MBR A;  1FFV C;  2GQT A;  2Y4G A;  3ETR B;  3EUB 3;  1W1Q A;  1ZR6 A;  2AXR A;  1AHV A;  2OAI A;  3NVZ B;  1UXY A;  2VFT A;  4XLO A;  4MLA A;  5AE1 A;  1N5W C;  2UUU A;  2W55 A;  2VFR A;  4PZF A;  3FW7 A;  5D79 A;  3AM9 A;  5HMR A;  3RJA A;  5AE3 A;  3PQB A;  3POP A;  1AHU A;  2IPI A;  3AMZ A;  2P3H A;  2Y3R A;  2I0K A;  3W8X A;  4ML8 A;  1N63 C;  2Q4W A;  1N60 C;  3W8W A;  5G5H B;  2VFS A;  3S1F A;  1DIQ A;  5G5G B;  5FXP A;  3D2J A;  1V97 A;  2BVH A;  1FFU C;  4PVE A;  1FIQ B;  3DQ0 A;  5FXD A;  2R2Z A;  1MBB A;  2QPM A;  3NVY B;  2PLI A;  4PVH A;  3C0P A;  1F0X A;  4BC7 A;  1DII A;  4JAY A;  1E8H A;  1I19 A;  5L6G A;  2RK5 A;  2GQU A;  5K8E A;  1W1J A;  4UD8 A;  5FXE A;  5FXF A;  1RM6 B;  1QLU A;  3NS1 B;  1JRP A;  3NVV B;  4OAL A;  2O3G A;  5I1V A;  1AHZ A;  3D2D A;  4BCA A;  4HG0 A;  4JB1 A;  1W1S A;  4PWC A;  1DZN A;  3RJ8 A;  3AN1 A;  2QKN A;  5ADZ A;  5L6F A;  3FWA A;  3FW9 A;  1W1O A;  1W1M A;  2W3S A;  3TSH A;  5HQX A;  1W1K A;  1ZXI C;  3TX1 A;  4BBY A;  2YVS A;  4O95 A;  2BVF A;  2Y3S A;  1MBT A;  1W1R A;  1E0Y A;  2VFU A;  1WVE A;  1WVF A;  2R8D A;  3D2H A;  3LLB A;  1N5X A;  1VDV A;  3VTE A;  3BW7 A;  1QLT A;  1JRO A;  2UUV A;  2PLS A;  1E8F A;  3PM9 A;  1N61 C;  2VFV A;  3I99 A;  3S1E A;  5I1W A;  1HSK A;  2W3R A;  1WYG A;  3FW8 A;  2P13 A;  2BVG A;  3GSY A;  3JS8 A;  4PVJ A;  1W1L A;  2P4P A;  2W54 A;  3LAE A;  5HHZ A;  3W8Z A;  4PWB A;  1SB3 B;  2Q85 A;  3DED A;  3NRZ B;  3HSU A;  3HRD C;  2VAO A;  1E8G A;  3TSJ A;  3B9J B;  1FO4 A;  3KJM A;  3S1D A;  2Y08 A;  2WDW A;  4PVK A;  5AWV A;  4BC9 A;  3SR6 B;  2E3T A;  1VAO A;  4ZOH B;  1T3Q C;  4PYT A;  3S1C A;  4DNS A;  5AE2 A;  1N62 C;  2NQW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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