4JAYA

Crystal structure of p. aeruginosa murb in complex with nadp+
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
338
structure length
338
Chain Sequence
SLELQEHCSLKPYNTFGIDVRARLLAHARDEADVREALALARERGLPLLVIGGGSNLLLTRDVEALVLRMASQGRRIVSDAADSVLVEAEAGEAWDPFVQWSLERGLAGLENLSLIPGTVGAAPMQNIGAYGVELKDVFDSLTALDRQDGTLREFDRQACRFGYRDSLFKQEPDRWLILRVRLRLTRRERLHLDYGPVRQRLEEEGIASPTARDVSRVICAIRREKLPDPAVLGNAGSFFKNPLVDATQAERLRQAFPDLVGYPQADGRLKLAAGWLIDKGGWKGFRDGPVGVHAQQALVLVNHGGATGAQVRALAERIQEDVRRRFGVELEPEPNLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Pseudomonas aeruginosa
molecule keywords UDP-N-acetylenolpyruvoylglucosamine reductase
total genus 99
structure length 338
sequence length 338
chains with identical sequence B, C, D
ec nomenclature ec 1.3.1.98: UDP-N-acetylmuramate dehydrogenase.
pdb deposition date 2013-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01565 FAD_binding_4 FAD binding domain
A PF02873 MurB_C UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.43.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 4jayA01
3.30.465.10 Alpha Beta 2-Layer Sandwich Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 4jayA02
3.90.78.10 Alpha Beta Alpha-Beta Complex Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 4jayA03
4BCAA 1F0XA 1QLUA 2AXRA 1E0YA 3FW9A 3S1EA 2O3GA 3AN1A 1FIQB 1V97A 1E8GA 4PVEA 4DNSA 1AHVA 1AHUA 2Q85A 1VAOA 4BBYA 3LAEA 3LLBA 2NQWA 4UD8A 2BVGA 1QLTA 3FW7A 2BVHA 3JS8A 5FXEA 3B9JB 4JB1A 1UXYA 2PLIA 3W8WA 2P13A 1ZR6A 3NRZB 3NVVB 1E8FA 1VDVA 1N5XA 2W3SA 1ZXIC 1E8HA 1DZNA 5AE2A 3W8ZA 1W1LA 3ETRB 3S1CA 4PWCA 4HG0A 3D2HA 4PVHA 3TSHA 5AE3A 3AM9A 2R2ZA 1T3QC 1N5WC 2QKNA 5G5HB 3TX1A 1DIIA 4XLOA 4ML8A 1JRPA 1W1QA 2VFVA 1N60C 1W1MA 5HQXA 1MBTA 1FFUC 2P4PA 4PWBA 1RM6B 3NVYB 3S1DA 2YVSA 3HRDC 3TSJA 4BC7A 2RK5A 3S1FA 2R8DA 1SB3B 1N62C 4PZFA 1W1RA 3NVZB 2P3HA 2OAIA 4O95A 2PLSA 4PYTA 5AE1A 2Q4WA 2W54A 4MLAA 3GSYA 1WVFA 3D2DA 3AMZA 2E3TA 3PM9A 4PVJA 5HHZA 3I99A 3KJMA 5FXDA 3SR6B 3C0PA 2W3RA 4PVKA 2W55A 5D79A 2QPMA 1DIQA 1N63C 3VTEA 2VFTA 3FWAA 2GQTA 4BC9A 1I19A 1HSKA 2EXRA 5ADZA 5FXPA 1N61C 1FFVC 1JROA 3FW8A 5HMRA 1W1JA 5FXFA 3NS1B 1WVEA 2VFRA 3EUB3 3W8XA 5G5GB 3DEDA 1FO4A 2VFUA 3DQ0A 1W1KA 1MBBA 3NVWB 1W1OA 2I0KA 1W1SA 2VFSA 4EC3A 3D2JA 2MBRA 4OALA 2BVFA 4ZOHB 3BW7A 4JAYA 1WYGA 1AHZA 2GQUA 2VAOA
chains in the Genus database with same CATH superfamily
4BCAA 1F0XA 1QLUA 2AXRA 1E0YA 3FW9A 3S1EA 2O3GA 3AN1A 1FIQB 1V97A 1E8GA 4PVEA 4DNSA 1AHVA 5I1VA 1AHUA 2Q85A 1VAOA 4BBYA 3LAEA 3LLBA 2NQWA 4UD8A 2BVGA 1QLTA 3FW7A 2BVHA 3JS8A 5FXEA 3B9JB 4JB1A 1UXYA 2PLIA 3W8WA 2P13A 3RJ8A 1ZR6A 3NRZB 3NVVB 1E8FA 1VDVA 1N5XA 2W3SA 1ZXIC 1E8HA 1DZNA 5AE2A 3W8ZA 3POPA 1W1LA 3ETRB 3S1CA 4PWCA 4HG0A 3D2HA 4PVHA 3TSHA 5AE3A 3AM9A 2R2ZA 1T3QC 1N5WC 2QKNA 5G5HB 5K8EA 3TX1A 1DIIA 4XLOA 4ML8A 1JRPA 1W1QA 2VFVA 2Y4GA 1N60C 1W1MA 5HQXA 1MBTA 1FFUC 2P4PA 4PWBA 5L6GA 1RM6B 3NVYB 2UUUA 3S1DA 2YVSA 3HRDC 3TSJA 4BC7A 2RK5A 3S1FA 2WDWA 2Y3SA 5L6FA 2R8DA 3PQBA 1SB3B 1N62C 4PZFA 1W1RA 3NVZB 3EJEB 2P3HA 2OAIA 4O95A 2PLSA 4PYTA 5AE1A 2Y3RA 2Q4WA 2W54A 4MLAA 3GSYA 1WVFA 3D2DA 3AMZA 2E3TA 3PM9A 3HSUA 4PVJA 5HHZA 3I99A 3KJMA 5FXDA 3RJAA 3SR6B 3C0PA 2W3RA 4PVKA 2W55A 5D79A 2QPMA 1DIQA 1N63C 3VTEA 2VFTA 3FWAA 5I1WA 2GQTA 4BC9A 1I19A 1HSKA 2EXRA 5ADZA 5FXPA 1N61C 1FFVC 1JROA 3FW8A 3EJBB 5HMRA 1W1JA 5FXFA 3NS1B 1WVEA 2VFRA 3EUB3 3W8XA 5G5GB 2Y08A 2UUVA 3DEDA 1FO4A 2VFUA 2IPIA 3DQ0A 1W1KA 1MBBA 3NVWB 1W1OA 2I0KA 1W1SA 2VFSA 3EJDB 4EC3A 3D2JA 5AWVA 2MBRA 4OALA 2BVFA 4ZOHB 3BW7A 4JAYA 1WYGA 1AHZA 2GQUA 2VAOA
chains in the Genus database with same CATH topology
4BCAA 1F0XA 1QLUA 2AXRA 1E0YA 3FW9A 3S1EA 2O3GA 3AN1A 1FIQB 1V97A 1E8GA 4PVEA 4DNSA 1AHVA 5I1VA 1AHUA 2Q85A 1VAOA 4BBYA 3LAEA 3LLBA 2NQWA 4UD8A 2BVGA 1QLTA 3FW7A 2BVHA 3JS8A 5FXEA 3B9JB 4JB1A 1UXYA 2PLIA 3W8WA 2P13A 3RJ8A 1ZR6A 3NRZB 3NVVB 1E8FA 1VDVA 1N5XA 2W3SA 1ZXIC 1E8HA 1DZNA 5AE2A 3W8ZA 3POPA 1W1LA 3ETRB 3S1CA 4PWCA 4HG0A 3D2HA 4PVHA 3TSHA 5AE3A 3AM9A 2R2ZA 1T3QC 1N5WC 2QKNA 5G5HB 5K8EA 3TX1A 1DIIA 4XLOA 4ML8A 1JRPA 1W1QA 2VFVA 2Y4GA 1N60C 1W1MA 5HQXA 1MBTA 1FFUC 2P4PA 4PWBA 5L6GA 1RM6B 2UUUA 3NVYB 3S1DA 2YVSA 3HRDC 3TSJA 4BC7A 2RK5A 3S1FA 2WDWA 2Y3SA 5L6FA 2R8DA 3PQBA 1SB3B 1N62C 4PZFA 1W1RA 3NVZB 2P3HA 2OAIA 4O95A 2PLSA 4PYTA 5AE1A 2Y3RA 2Q4WA 2W54A 4MLAA 3GSYA 1WVFA 3D2DA 3AMZA 2E3TA 3PM9A 3HSUA 4PVJA 5HHZA 3I99A 3KJMA 5FXDA 3RJAA 3SR6B 3C0PA 2W3RA 4PVKA 2W55A 5D79A 2QPMA 1DIQA 1N63C 3VTEA 2VFTA 3FWAA 5I1WA 2GQTA 4BC9A 1I19A 1HSKA 2EXRA 5ADZA 5FXPA 1N61C 1FFVC 1JROA 3FW8A 5HMRA 1W1JA 5FXFA 3NS1B 1WVEA 2VFRA 3EUB3 3W8XA 5G5GB 2Y08A 2UUVA 3DEDA 1FO4A 2VFUA 2IPIA 3DQ0A 1W1KA 1MBBA 3NVWB 1W1OA 2I0KA 1W1SA 2VFSA 4EC3A 3D2JA 5AWVA 2MBRA 4OALA 2BVFA 4ZOHB 3BW7A 4JAYA 1WYGA 1AHZA 2GQUA 2VAOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BCA A;  1F0X A;  1QLU A;  2AXR A;  1E0Y A;  3FW9 A;  3S1E A;  2O3G A;  3AN1 A;  1FIQ B;  1V97 A;  1E8G A;  4PVE A;  4DNS A;  1AHV A;  1AHU A;  2Q85 A;  1VAO A;  4BBY A;  3LAE A;  3LLB A;  2NQW A;  4UD8 A;  2BVG A;  1QLT A;  3FW7 A;  2BVH A;  3JS8 A;  5FXE A;  3B9J B;  4JB1 A;  1UXY A;  2PLI A;  3W8W A;  2P13 A;  1ZR6 A;  3NRZ B;  3NVV B;  1E8F A;  1VDV A;  1N5X A;  2W3S A;  1ZXI C;  1E8H A;  1DZN A;  5AE2 A;  3W8Z A;  1W1L A;  3ETR B;  3S1C A;  4PWC A;  4HG0 A;  3D2H A;  4PVH A;  3TSH A;  5AE3 A;  3AM9 A;  2R2Z A;  1T3Q C;  1N5W C;  2QKN A;  5G5H B;  3TX1 A;  1DII A;  4XLO A;  4ML8 A;  1JRP A;  1W1Q A;  2VFV A;  1N60 C;  1W1M A;  5HQX A;  1MBT A;  1FFU C;  2P4P A;  4PWB A;  1RM6 B;  3NVY B;  3S1D A;  2YVS A;  3HRD C;  3TSJ A;  4BC7 A;  2RK5 A;  3S1F A;  2R8D A;  1SB3 B;  1N62 C;  4PZF A;  1W1R A;  3NVZ B;  2P3H A;  2OAI A;  4O95 A;  2PLS A;  4PYT A;  5AE1 A;  2Q4W A;  2W54 A;  4MLA A;  3GSY A;  1WVF A;  3D2D A;  3AMZ A;  2E3T A;  3PM9 A;  4PVJ A;  5HHZ A;  3I99 A;  3KJM A;  5FXD A;  3SR6 B;  3C0P A;  2W3R A;  4PVK A;  2W55 A;  5D79 A;  2QPM A;  1DIQ A;  1N63 C;  3VTE A;  2VFT A;  3FWA A;  2GQT A;  4BC9 A;  1I19 A;  1HSK A;  2EXR A;  5ADZ A;  5FXP A;  1N61 C;  1FFV C;  1JRO A;  3FW8 A;  5HMR A;  1W1J A;  5FXF A;  3NS1 B;  1WVE A;  2VFR A;  3EUB 3;  3W8X A;  5G5G B;  3DED A;  1FO4 A;  2VFU A;  3DQ0 A;  1W1K A;  1MBB A;  3NVW B;  1W1O A;  2I0K A;  1W1S A;  2VFS A;  4EC3 A;  3D2J A;  2MBR A;  4OAL A;  2BVF A;  4ZOH B;  3BW7 A;  4JAY A;  1WYG A;  1AHZ A;  2GQU A;  2VAO A; 
#chains in the Genus database with same CATH topology
 4BCA A;  1F0X A;  1QLU A;  2AXR A;  1E0Y A;  3FW9 A;  3S1E A;  2O3G A;  3AN1 A;  1FIQ B;  1V97 A;  1E8G A;  4PVE A;  4DNS A;  1AHV A;  5I1V A;  1AHU A;  2Q85 A;  1VAO A;  4BBY A;  3LAE A;  3LLB A;  2NQW A;  4UD8 A;  2BVG A;  1QLT A;  3FW7 A;  2BVH A;  3JS8 A;  5FXE A;  3B9J B;  4JB1 A;  1UXY A;  2PLI A;  3W8W A;  2P13 A;  3RJ8 A;  1ZR6 A;  3NRZ B;  3NVV B;  1E8F A;  1VDV A;  1N5X A;  2W3S A;  1ZXI C;  1E8H A;  1DZN A;  5AE2 A;  3W8Z A;  3POP A;  1W1L A;  3ETR B;  3S1C A;  4PWC A;  4HG0 A;  3D2H A;  4PVH A;  3TSH A;  5AE3 A;  3AM9 A;  2R2Z A;  1T3Q C;  1N5W C;  2QKN A;  5G5H B;  5K8E A;  3TX1 A;  1DII A;  4XLO A;  4ML8 A;  1JRP A;  1W1Q A;  2VFV A;  2Y4G A;  1N60 C;  1W1M A;  5HQX A;  1MBT A;  1FFU C;  2P4P A;  4PWB A;  5L6G A;  1RM6 B;  3NVY B;  2UUU A;  3S1D A;  2YVS A;  3HRD C;  3TSJ A;  4BC7 A;  2RK5 A;  3S1F A;  2WDW A;  2Y3S A;  5L6F A;  2R8D A;  3PQB A;  1SB3 B;  1N62 C;  4PZF A;  1W1R A;  3NVZ B;  3EJE B;  2P3H A;  2OAI A;  4O95 A;  2PLS A;  4PYT A;  5AE1 A;  2Y3R A;  2Q4W A;  2W54 A;  4MLA A;  3GSY A;  1WVF A;  3D2D A;  3AMZ A;  2E3T A;  3PM9 A;  3HSU A;  4PVJ A;  5HHZ A;  3I99 A;  3KJM A;  5FXD A;  3RJA A;  3SR6 B;  3C0P A;  2W3R A;  4PVK A;  2W55 A;  5D79 A;  2QPM A;  1DIQ A;  1N63 C;  3VTE A;  2VFT A;  3FWA A;  5I1W A;  2GQT A;  4BC9 A;  1I19 A;  1HSK A;  2EXR A;  5ADZ A;  5FXP A;  1N61 C;  1FFV C;  1JRO A;  3FW8 A;  3EJB B;  5HMR A;  1W1J A;  5FXF A;  3NS1 B;  1WVE A;  2VFR A;  3EUB 3;  3W8X A;  5G5G B;  2Y08 A;  2UUV A;  3DED A;  1FO4 A;  2VFU A;  2IPI A;  3DQ0 A;  1W1K A;  1MBB A;  3NVW B;  1W1O A;  2I0K A;  1W1S A;  2VFS A;  3EJD B;  4EC3 A;  3D2J A;  5AWV A;  2MBR A;  4OAL A;  2BVF A;  4ZOH B;  3BW7 A;  4JAY A;  1WYG A;  1AHZ A;  2GQU A;  2VAO A; 
#chains in the Genus database with same CATH homology
 4BCA A;  1F0X A;  1QLU A;  2AXR A;  1E0Y A;  3FW9 A;  3S1E A;  2O3G A;  3AN1 A;  1FIQ B;  1V97 A;  1E8G A;  4PVE A;  4DNS A;  1AHV A;  5I1V A;  1AHU A;  2Q85 A;  1VAO A;  4BBY A;  3LAE A;  3LLB A;  2NQW A;  4UD8 A;  2BVG A;  1QLT A;  3FW7 A;  2BVH A;  3JS8 A;  5FXE A;  3B9J B;  4JB1 A;  1UXY A;  2PLI A;  3W8W A;  2P13 A;  3RJ8 A;  1ZR6 A;  3NRZ B;  3NVV B;  1E8F A;  1VDV A;  1N5X A;  2W3S A;  1ZXI C;  1E8H A;  1DZN A;  5AE2 A;  3W8Z A;  3POP A;  1W1L A;  3ETR B;  3S1C A;  4PWC A;  4HG0 A;  3D2H A;  4PVH A;  3TSH A;  5AE3 A;  3AM9 A;  2R2Z A;  1T3Q C;  1N5W C;  2QKN A;  5G5H B;  5K8E A;  3TX1 A;  1DII A;  4XLO A;  4ML8 A;  1JRP A;  1W1Q A;  2VFV A;  2Y4G A;  1N60 C;  1W1M A;  5HQX A;  1MBT A;  1FFU C;  2P4P A;  4PWB A;  5L6G A;  1RM6 B;  2UUU A;  3NVY B;  3S1D A;  2YVS A;  3HRD C;  3TSJ A;  4BC7 A;  2RK5 A;  3S1F A;  2WDW A;  2Y3S A;  5L6F A;  2R8D A;  3PQB A;  1SB3 B;  1N62 C;  4PZF A;  1W1R A;  3NVZ B;  2P3H A;  2OAI A;  4O95 A;  2PLS A;  4PYT A;  5AE1 A;  2Y3R A;  2Q4W A;  2W54 A;  4MLA A;  3GSY A;  1WVF A;  3D2D A;  3AMZ A;  2E3T A;  3PM9 A;  3HSU A;  4PVJ A;  5HHZ A;  3I99 A;  3KJM A;  5FXD A;  3RJA A;  3SR6 B;  3C0P A;  2W3R A;  4PVK A;  2W55 A;  5D79 A;  2QPM A;  1DIQ A;  1N63 C;  3VTE A;  2VFT A;  3FWA A;  5I1W A;  2GQT A;  4BC9 A;  1I19 A;  1HSK A;  2EXR A;  5ADZ A;  5FXP A;  1N61 C;  1FFV C;  1JRO A;  3FW8 A;  5HMR A;  1W1J A;  5FXF A;  3NS1 B;  1WVE A;  2VFR A;  3EUB 3;  3W8X A;  5G5G B;  2Y08 A;  2UUV A;  3DED A;  1FO4 A;  2VFU A;  2IPI A;  3DQ0 A;  1W1K A;  1MBB A;  3NVW B;  1W1O A;  2I0K A;  1W1S A;  2VFS A;  4EC3 A;  3D2J A;  5AWV A;  2MBR A;  4OAL A;  2BVF A;  4ZOH B;  3BW7 A;  4JAY A;  1WYG A;  1AHZ A;  2GQU A;  2VAO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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