1GSZA

Crystal structure of a squalene cyclase in complex with the potential anticholesteremic drug ro48-8071
Total Genus 230
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
230
sequence length
619
structure length
619
Chain Sequence
AYARTLDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDRDRMEKIRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEEPMQKALRFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSWARATVVALSIVMSRQPVFPLPERARVPELYETDVPPRRRGAKGGGGWIFDALDRALHGYQKLSVHPFRRAAEIRALDWLLERQAGDGSWGGIQPPWFYALIALKILDMTQHPAFIKGWEGLELYGVELDYGGWMFQASISPVWDTGLAVLALRAAGLPADHDRLVKAGEWLLDRQITVPGDWAVKRPNLKPGGFAFQFDNVYYPDVDDTAVVVWALNTLRLPDERRRRDAMTKGFRWIVGMQSSNGGWGAYDVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSFGYDDAWKVIRRAVEYLKREQKPDGSWFGRWGVNYLYGTGAVVSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSYEDPAYAGKGASTPSQTAWALMALIAGGRAESEAARRGVQYLVETQRPDGGWDEPYYTGTGFPGDFYLGYTMYRHVFPTLALGRYKQAI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords SQUALENE--HOPENE CYCLASE
publication title Crystal Structure of a Squalene Cyclase in Complex with the Potential Anticholesteremic Drug Ro48-8071
pubmed doi rcsb
source organism Alicyclobacillus acidocaldarius
molecule tags Isomerase
total genus 230
structure length 619
sequence length 619
chains with identical sequence B, C
ec nomenclature ec 4.2.1.129: Squalene--hopanol cyclase.
pdb deposition date 2002-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
A PF13243 SQHop_cyclase_C Squalene-hopene cyclase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1gszA01
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1gszA02
1GXNA 1MZCB 3E33B 1O5MB 2H6GB 1GSZA 2NOJA 2WY7A 3E37B 4LNVA 4D4AA 4D94A 1SA5B 4L9PB 5FO7B 3Q75B 2WIIB 1N4SB 1LD8B 1TN8B 1W6KA 1H36A 1LTXB 4MU9A 1S64B 1QBQB 3DRAB 4FXKB 2H6FB 4FXGB 2B39A 3E32B 3Q78B 1TNZB 1R76A 5JPMB 1FPPB 1D8EB 3HXDB 4GTTB 4ZRQA 2IEJB 1GHQA 1H3CA 1N9AB 3DSVB 1O1TB 1N4QB 3Q7FB 2ZISB 1N4RB 1FT2B 3CU7A 1TN6B 3DSXB 4D4BA 2G02A 3HXEB 1N94B 2XWJB 1DCEB 3OEDA 1H3AA 1NL4B 1SA4B 1X81B 2H6HB 3DSWB 2R2LB 3EUVB 3SFXB 3SFYB 2BB5A 2V3PA 3KSQB 1TNBB 4GTVB 3D5SA 5JPNB 4ZRPA 1LD7B 3DSTB 2BBCA 5AGDA 4GTMB 2I07B 2BB6A 4KKJA 1UMPA 1O6HA 3K7XA 3SQCA 3PZ3B 4C1SA 1QSJA 4GTRB 4GTOB 1TNUB 3HXFB 1C3DA 1O1RB 3C72B 3PZ2B 1W6JA 1N4PB 1GXOA 3Q7AB 1O6RA 1O6QA 3EU5B 3HXBB 2GOXA 4EHMB 3KSLB 4GTSB 3KQ4A 1TN7B 3PZ1B 4LNGB 3DPYB 1S63B 3E34B 4YDEB 1TNYB 1N95B 2F0YB 1JCSB 4D4CA 2XWBB 1O1SB 2G0DA 4ZH1A 1FT1B 5FOBB 1TNOB 1O79A 4KKIA 3HXCB 2H6IB 2WINB 3DSSB 4GTQB 1SQCA 1H39A 1H37A 3Q73B 1JCRB 1H35A 2V8KA 3PZ4B 4LNBB 4BOJA 4YDOB 5FO9B 2A73B 2SQCA 3KLSA 4ONTA 3OXUA 3E30B 3D5RA 2V3NA 3G6JB 1D8DB 1KZPB 1KZOB 4GTPB 1HZFA 4D4DA 4V1SA 2PMVA 3RJ3A 3DSUB 2V8JA 2ZIRB 4BOKA 2PN5A 1GXMA 1JCQB 1NI1B 4M76A 1QQFA 5FO8B 4MBGB 2XQWA 3Q79B 1H3BA 2BEDB 2V8IA 2WY8A 4V1RA
chains in the Genus database with same CATH superfamily
2ZZRA 3X17A 1OJNA 2E22A 2H6GB 3E37B 3QXFA 1LF9A 1I8QA 3T33A 1TN8B 3SAEA 1LTXB 3W5NA 3VXDA 3QG0A 3AFLA 4ZG8A 4FXKB 3W5MA 3E32B 1H13A 1GAIA 2NVPA 3M76A 3HXDB 2DROA 2VN7A 1FO3A 4FNVA 1HN0A 3WKFA 1F1SA 1N4QB 3A3VA 5M7YA 4MMIA 3WKIA 5MEHA 1N4RB 3QWTA 1KWFA 3PYAA 5DGQA 1N23A 1NL4B 3SFXB 2D5JA 4RNQA 3EUVB 1N7NA 1FO2A 3SFYB 3KSQB 1WU6A 4GL3A 4GTVB 3D5SA 2EADA 3PMMA 5JPNB 1L2AA 3QT3A 1FCEA 1N7PA 2BBCA 2YIKA 2I07B 4GTMB 3SDRA 1V7VA 1UMPA 3W7XA 2Q1FA 1ULVA 3GZKA 1K72A 3WIWA 3RX8A 1O6RA 3EU5B 4YCRA 3M01A 1RQ5A 3KSLB 4FJQA 3KQ4A 3PZ1B 2OKXA 4LNGB 1OJMA 1S63B 1TNYB 4Q88A 2F0YB 5CD2A 2XWBB 2G0DA 1J0MA 1XW2A 3ACSA 1LF6A 5FOBB 4Q2BA 2BRPA 3HXCB 2FUTA 3E6UA 1RWHA 1H37A 2FUZA 3QSPA 2V8KA 1HV6A 1X9DA 1KFGA 1HCUA 3M7BA 4ONTA 2Z07A 1D8DB 1KZPB 4D4DA 4V1SA 2DRSA 3DSUB 2V8JA 3H2WA 1LXKA 3P2CA 1JCQB 1N7RA 5IL3A 3QRYA 1DOGA 3S4CA 4QT9A 1XWTA 2GZ6A 1MZCB 1KSDA 1CLCA 5C05A 4LNVA 4D4AA 1SA5B 4L9PB 3NNBA 3Q75B 1C82A 1W6KA 3QDEA 1G6IA 1H36A 5JMDA 1CEMA 4KTPA 5CZLA 4WVBA 3DRAB 3ANJA 5GY3A 1KSCA 5JPMB 1FPPB 3ANIA 1D8EB 5EASA 2IEJB 1GHQA 1N9AB 1O1TB 2VN4A 5DGRA 1HM3A 3Q7FB 4CJ0A 3N0FA 1FT2B 3CU7A 3DSXB 1N94B 2XWJB 3S9VA 4OJZA 1X81B 2R2LB 2BB5A 5EAUA 3ANKA 1AGMA 1TNBB 4TF4A 2F6DA 5IKAA 4NEIA 5AGDA 1CB8A 1L1YA 3WIQA 2AHFA 5JMFA 3W7TA 4GTRB 4GTOB 2QNOA 1O1RB 1NC5A 3M02A 3PZ2B 4AYPA 1N4PB 1GLMA 1GXOA 1LOHA 2EABA 4WVCA 2GOXA 1DL2A 1TN7B 1IA7A 3DPYB 2JF4A 1G87A 3E34B 1N95B 4D4CA 1LXMA 4JJJA 4DI5A 1GA2A 3P5RA 5EATA 1J0NA 3M00A 1O79A 3WKGA 3W7WA 4AYQA 3SDQA 2H6IB 4CE7A 2CQSA 3W7SA 3DSSB 2EACA 1H39A 3Q73B 1RWGA 3A0OA 1RWAA 4BOJA 2A73B 2SQCA 3KLSA 1HXCA 3E30B 3W7UA 3G6JB 4DOEA 2FBAA 3M75A 1HZFA 3EQAA 1KKTA 2FV0A 3G4FA 3M72A 3G4DA 3H3KA 3WC3A 3E80A 5GW7A 1QQFA 5IKHA 2XQWA 1H3BA 4OZWA 4EL8A 1FBWA 4E1YA 1N7QA 1KREA 3E33B 1GSZA 5IK9A 4J5TA 1H54A 2XFGA 2WIIB 1LD8B 2X03A 3TF4A 5ILDA 5ILJA 2ONHA 4MU9A 2RI8A 1X1IA 1S64B 5ILZA 1N1ZA 3SDUA 2H6FB 3EZ8A 1UT9A 2B39A 1X1HA 3Q78B 1TNZB 1R76A 3VSNA 4OK4A 5ILYA 2A8ZA 4GTTB 1WU5A 1IA6A 3WKHA 2B4FA 1HXGA 4F10A 3K11A 1FBOA 1V5CA 3DSVB 3GT5A 1UG9A 2BRVX 1GAHA 4D4BA 1OJOA 2G02A 1F9GA 1DCEB 3E73A 1KRFA 1SA4B 2WCOA 3NFVA 5M7IA 4OK2A 3S4BA 4ZRPA 3RRSA 1LD7B 3DSTB 3M7CA 2ONGA 2RI9A 3M71A 4XUVA 2WYNA 3WUXA 4C1SA 4Z4LA 1QSJA 3QFZA 1RWFA 3ACTA 1C3DA 5ILKA 3C72B 1W6JA 5ILIA 1WU4A 1VD5A 3Q7AB 1O6QA 3HXBB 1FP3A 4EHMB 4GAXA 4DODA 2BRWA 1JCSB 1O1SB 4ZH1A 1RWCA 4L0GA 1TNOB 3M74A 3H7LA 4ZH5A 1N20A 5DHKA 3CIHA 1HMWA 1KS8A 1SQCA 4GTQB 1JCRB 1OJPA 1H35A 4AYRA 3M7LA 3PZ4B 4LNBB 4KTRA 2WDAA 2V3NA 2JG0A 1KZOB 4GTPB 4F13A 1G9GA 3E7JA 3RJ3A 3RX7A 3S4AA 1HM2A 2ZIRB 4L6XA 5GZKA 5IK0A 2PN5A 1GXMA 1WZZA 4M76A 4MBGB 4CJ1A 3Q79B 2ZBLA 1JS4A 1X1JA 3QXQA 2WY8A 2RGKA 1GXNA 1O5MB 2FUQA 2NOJA 2WY7A 5DHIA 3RSYA 4D94A 5FO7B 1N7OA 1N4SB 5ILHA 1QBQB 1HX9A 1XWQA 1F9DA 4FXGB 1N21A 3SDTA 3QFYA 4ZRQA 3ON6A 4LIXA 5E2JA 1H3CA 1FAEA 3SDVA 5KKBA 3GLYA 4AYOA 5CA3A 2ZISB 1N1BA 1QAZA 5IL8A 1TN6B 3M77A 1FMIA 3HXEB 3LZ9A 4FUSA 4TXTA 3OEDA 3AFJA 3DSWB 1H3AA 3RENA 2H6HB 3RX5A 4WVAA 1TF4A 2V3PA 1V5DA 2J5CA 3PYBA 1W3YA 5IM1A 1EGUA 3VSMA 2BB6A 2DRQA 1V7WA 4KKJA 2P0VA 1O6HA 3K7XA 3SQCA 3PZ3B 1H14A 1N22A 4OZVA 1TNUB 4Z4JA 3S4DA 3HXFB 3P5PA 2AFAA 3QT9A 4GTSB 3WIRA 1AYXA 3N0GA 1V7XA 4YDEB 1IS9A 2FV1A 1FT1B 1NXCA 2CQTA 4KKIA 2GH4A 2WINB 3M73A 2DRRA 3EU8A 1N24A 1F9OA 1H12A 1RW9A 4YDOB 5FO9B 1G9JA 2JJBA 3M7EA 3OXUA 4WU0A 3D5RA 3QPFA 4MMHA 2EAEA 3D3IA 5IK6A 2PMVA 2E24A 1HMUA 1HXAA 4BOKA 3VW5A 1NI1B 3M78A 5FO8B 2D8LA 2BEDB 2V8IA 2AHGA 4V1RA
chains in the Genus database with same CATH topology
2ZZRA 3X17A 2H6GB 3E37B 3QXFA 1LF9A 3T33A 1TN8B 3SAEA 1LTXB 3W5NA 3VXDA 3QG0A 4ZG8A 4FXKB 3W5MA 3E32B 1H13A 1GAIA 2NVPA 3M76A 3HXDB 2DROA 2VN7A 1FO3A 3WKFA 1N4QB 3WKIA 3A3VA 5M7YA 5MEHA 1N4RB 3QWTA 1KWFA 3PYAA 5DGQA 1NL4B 3SFXB 2D5JA 3EUVB 1FO2A 3SFYB 3KSQB 1WU6A 4GL3A 4GTVB 3D5SA 2EADA 3PMMA 5JPNB 1L2AA 3QT3A 1FCEA 2BBCA 2YIKA 2I07B 4GTMB 3SDRA 1V7VA 1UMPA 3W7XA 1ULVA 3GZKA 1K72A 3WIWA 3RX8A 1O6RA 3EU5B 4YCRA 1RQ5A 3KSLB 3KQ4A 3PZ1B 2OKXA 4LNGB 1S63B 1TNYB 4Q88A 2F0YB 5CD2A 2XWBB 2G0DA 1XW2A 3ACSA 1LF6A 5FOBB 4Q2BA 3HXCB 3E6UA 1H37A 2FUZA 3QSPA 2V8KA 1X9DA 1KFGA 1HCUA 3M7BA 4ONTA 2Z07A 1D8DB 1KZPB 4D4DA 4V1SA 2DRSA 3DSUB 2V8JA 3H2WA 3P2CA 1JCQB 3QRYA 1DOGA 3S4CA 4QT9A 1XWTA 2GZ6A 1MZCB 1KSDA 1CLCA 4LNVA 4D4AA 1SA5B 4L9PB 3Q75B 1W6KA 3QDEA 1G6IA 1H36A 1CEMA 4KTPA 5CZLA 4WVBA 3DRAB 3ANJA 5GY3A 1KSCA 5JPMB 1FPPB 3ANIA 1D8EB 2IEJB 1GHQA 1N9AB 1O1TB 2VN4A 5DGRA 3Q7FB 4CJ0A 1FT2B 3CU7A 3DSXB 1N94B 2XWJB 3S9VA 1X81B 2R2LB 2BB5A 3ANKA 1AGMA 1TNBB 4TF4A 2F6DA 5AGDA 1L1YA 3WIQA 2AHFA 3W7TA 4GTRB 4GTOB 2QNOA 1O1RB 1NC5A 3PZ2B 4AYPA 1N4PB 1GLMA 1GXOA 2EABA 4WVCA 2GOXA 1DL2A 1TN7B 1IA7A 3DPYB 2JF4A 1G87A 3E34B 1N95B 4D4CA 4JJJA 1GA2A 3P5RA 1O79A 3WKGA 3W7WA 4AYQA 3SDQA 2H6IB 4CE7A 2CQSA 3W7SA 3DSSB 2EACA 1H39A 3Q73B 4BOJA 2A73B 2SQCA 3KLSA 3E30B 3W7UA 3G6JB 4DOEA 2FBAA 3M75A 1HZFA 3EQAA 1KKTA 2FV0A 3M72A 3H3KA 3WC3A 5GW7A 1QQFA 2XQWA 1H3BA 4EL8A 1FBWA 1KREA 3E33B 1GSZA 4J5TA 1H54A 2XFGA 2WIIB 1LD8B 3TF4A 4MU9A 2RI8A 1S64B 3SDUA 2H6FB 3EZ8A 1UT9A 2B39A 3Q78B 1TNZB 1R76A 2A8ZA 4GTTB 1WU5A 1IA6A 3WKHA 2B4FA 3K11A 1FBOA 1V5CA 3DSVB 3GT5A 1UG9A 1GAHA 4D4BA 2G02A 1DCEB 3E73A 1KRFA 1SA4B 5M7IA 3S4BA 4ZRPA 3RRSA 1LD7B 3DSTB 3M7CA 2RI9A 3M71A 4XUVA 2WYNA 3WUXA 4C1SA 4Z4LA 1QSJA 3QFZA 3ACTA 1C3DA 3C72B 1W6JA 1WU4A 1VD5A 3Q7AB 1O6QA 3HXBB 1FP3A 4EHMB 4DODA 1JCSB 1O1SB 4ZH1A 4L0GA 1TNOB 3M74A 3H7LA 4ZH5A 3CIHA 1KS8A 1SQCA 4GTQB 1JCRB 1H35A 4AYRA 3M7LA 3PZ4B 4LNBB 4KTRA 2V3NA 2JG0A 1KZOB 4GTPB 1G9GA 3RJ3A 3RX7A 3S4AA 2ZIRB 4L6XA 5GZKA 2PN5A 1GXMA 1WZZA 4M76A 4MBGB 4CJ1A 3Q79B 2ZBLA 1JS4A 3QXQA 2WY8A 2RGKA 1GXNA 1O5MB 2NOJA 2WY7A 3RSYA 4D94A 5FO7B 1N4SB 1QBQB 1XWQA 1F9DA 4FXGB 3SDTA 3QFYA 4ZRQA 3ON6A 4LIXA 5E2JA 1H3CA 1FAEA 3SDVA 5KKBA 3GLYA 4AYOA 5CA3A 2ZISB 1TN6B 3M77A 1FMIA 3HXEB 4FUSA 4TXTA 3OEDA 3AFJA 1H3AA 3DSWB 3RENA 2H6HB 3RX5A 4WVAA 1TF4A 2V3PA 1V5DA 3PYBA 2BB6A 2DRQA 1V7WA 4KKJA 2P0VA 1O6HA 3K7XA 3SQCA 3PZ3B 1H14A 1TNUB 4Z4JA 3S4DA 3HXFB 3P5PA 2AFAA 3QT9A 4GTSB 3WIRA 1AYXA 1V7XA 4YDEB 1IS9A 2FV1A 1FT1B 1NXCA 2CQTA 4KKIA 2GH4A 2WINB 3M73A 2DRRA 3EU8A 1F9OA 1H12A 4YDOB 5FO9B 1G9JA 2JJBA 3M7EA 3OXUA 4WU0A 3D5RA 3QPFA 2EAEA 3D3IA 2PMVA 4BOKA 3VW5A 1NI1B 3M78A 5FO8B 2D8LA 2BEDB 2V8IA 2AHGA 4V1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GXN A;  1MZC B;  3E33 B;  1O5M B;  2H6G B;  1GSZ A;  2NOJ A;  2WY7 A;  3E37 B;  4LNV A;  4D4A A;  4D94 A;  1SA5 B;  4L9P B;  5FO7 B;  3Q75 B;  2WII B;  1N4S B;  1LD8 B;  1TN8 B;  1W6K A;  1H36 A;  1LTX B;  4MU9 A;  1S64 B;  1QBQ B;  3DRA B;  4FXK B;  2H6F B;  4FXG B;  2B39 A;  3E32 B;  3Q78 B;  1TNZ B;  1R76 A;  5JPM B;  1FPP B;  1D8E B;  3HXD B;  4GTT B;  4ZRQ A;  2IEJ B;  1GHQ A;  1H3C A;  1N9A B;  3DSV B;  1O1T B;  1N4Q B;  3Q7F B;  2ZIS B;  1N4R B;  1FT2 B;  3CU7 A;  1TN6 B;  3DSX B;  4D4B A;  2G02 A;  3HXE B;  1N94 B;  2XWJ B;  1DCE B;  3OED A;  1H3A A;  1NL4 B;  1SA4 B;  1X81 B;  2H6H B;  3DSW B;  2R2L B;  3EUV B;  3SFX B;  3SFY B;  2BB5 A;  2V3P A;  3KSQ B;  1TNB B;  4GTV B;  3D5S A;  5JPN B;  4ZRP A;  1LD7 B;  3DST B;  2BBC A;  5AGD A;  4GTM B;  2I07 B;  2BB6 A;  4KKJ A;  1UMP A;  1O6H A;  3K7X A;  3SQC A;  3PZ3 B;  4C1S A;  1QSJ A;  4GTR B;  4GTO B;  1TNU B;  3HXF B;  1C3D A;  1O1R B;  3C72 B;  3PZ2 B;  1W6J A;  1N4P B;  1GXO A;  3Q7A B;  1O6R A;  1O6Q A;  3EU5 B;  3HXB B;  2GOX A;  4EHM B;  3KSL B;  4GTS B;  3KQ4 A;  1TN7 B;  3PZ1 B;  4LNG B;  3DPY B;  1S63 B;  3E34 B;  4YDE B;  1TNY B;  1N95 B;  2F0Y B;  1JCS B;  4D4C A;  2XWB B;  1O1S B;  2G0D A;  4ZH1 A;  1FT1 B;  5FOB B;  1TNO B;  1O79 A;  4KKI A;  3HXC B;  2H6I B;  2WIN B;  3DSS B;  4GTQ B;  1SQC A;  1H39 A;  1H37 A;  3Q73 B;  1JCR B;  1H35 A;  2V8K A;  3PZ4 B;  4LNB B;  4BOJ A;  4YDO B;  5FO9 B;  2A73 B;  2SQC A;  3KLS A;  4ONT A;  3OXU A;  3E30 B;  3D5R A;  2V3N A;  3G6J B;  1D8D B;  1KZP B;  1KZO B;  4GTP B;  1HZF A;  4D4D A;  4V1S A;  2PMV A;  3RJ3 A;  3DSU B;  2V8J A;  2ZIR B;  4BOK A;  2PN5 A;  1GXM A;  1JCQ B;  1NI1 B;  4M76 A;  1QQF A;  5FO8 B;  4MBG B;  2XQW A;  3Q79 B;  1H3B A;  2BED B;  2V8I A;  2WY8 A;  4V1R A; 
#chains in the Genus database with same CATH topology
 2ZZR A;  3X17 A;  1OJN A;  2E22 A;  2H6G B;  3E37 B;  3QXF A;  1LF9 A;  1I8Q A;  3T33 A;  1TN8 B;  3SAE A;  1LTX B;  3W5N A;  3VXD A;  3QG0 A;  3AFL A;  4ZG8 A;  4FXK B;  3W5M A;  3E32 B;  1H13 A;  1GAI A;  2NVP A;  3M76 A;  3HXD B;  2DRO A;  2VN7 A;  1FO3 A;  4FNV A;  1HN0 A;  3WKF A;  1F1S A;  1N4Q B;  3A3V A;  5M7Y A;  4MMI A;  3WKI A;  5MEH A;  1N4R B;  3QWT A;  1KWF A;  3PYA A;  5DGQ A;  1N23 A;  1NL4 B;  3SFX B;  2D5J A;  4RNQ A;  3EUV B;  1N7N A;  1FO2 A;  3SFY B;  3KSQ B;  1WU6 A;  4GL3 A;  4GTV B;  3D5S A;  2EAD A;  3PMM A;  5JPN B;  1L2A A;  3QT3 A;  1FCE A;  1N7P A;  2BBC A;  2YIK A;  2I07 B;  4GTM B;  3SDR A;  1V7V A;  1UMP A;  3W7X A;  2Q1F A;  1ULV A;  3GZK A;  1K72 A;  3WIW A;  3RX8 A;  1O6R A;  3EU5 B;  4YCR A;  3M01 A;  1RQ5 A;  3KSL B;  4FJQ A;  3KQ4 A;  3PZ1 B;  2OKX A;  4LNG B;  1OJM A;  1S63 B;  1TNY B;  4Q88 A;  2F0Y B;  5CD2 A;  2XWB B;  2G0D A;  1J0M A;  1XW2 A;  3ACS A;  1LF6 A;  5FOB B;  4Q2B A;  2BRP A;  3HXC B;  2FUT A;  3E6U A;  1RWH A;  1H37 A;  2FUZ A;  3QSP A;  2V8K A;  1HV6 A;  1X9D A;  1KFG A;  1HCU A;  3M7B A;  4ONT A;  2Z07 A;  1D8D B;  1KZP B;  4D4D A;  4V1S A;  2DRS A;  3DSU B;  2V8J A;  3H2W A;  1LXK A;  3P2C A;  1JCQ B;  1N7R A;  5IL3 A;  3QRY A;  1DOG A;  3S4C A;  4QT9 A;  1XWT A;  2GZ6 A;  1MZC B;  1KSD A;  1CLC A;  5C05 A;  4LNV A;  4D4A A;  1SA5 B;  4L9P B;  3NNB A;  3Q75 B;  1C82 A;  1W6K A;  3QDE A;  1G6I A;  1H36 A;  5JMD A;  1CEM A;  4KTP A;  5CZL A;  4WVB A;  3DRA B;  3ANJ A;  5GY3 A;  1KSC A;  5JPM B;  1FPP B;  3ANI A;  1D8E B;  5EAS A;  2IEJ B;  1GHQ A;  1N9A B;  1O1T B;  2VN4 A;  5DGR A;  1HM3 A;  3Q7F B;  4CJ0 A;  3N0F A;  1FT2 B;  3CU7 A;  3DSX B;  1N94 B;  2XWJ B;  3S9V A;  4OJZ A;  1X81 B;  2R2L B;  2BB5 A;  5EAU A;  3ANK A;  1AGM A;  1TNB B;  4TF4 A;  2F6D A;  5IKA A;  4NEI A;  5AGD A;  1CB8 A;  1L1Y A;  3WIQ A;  2AHF A;  5JMF A;  3W7T A;  4GTR B;  4GTO B;  2QNO A;  1O1R B;  1NC5 A;  3M02 A;  3PZ2 B;  4AYP A;  1N4P B;  1GLM A;  1GXO A;  1LOH A;  2EAB A;  4WVC A;  2GOX A;  1DL2 A;  1TN7 B;  1IA7 A;  3DPY B;  2JF4 A;  1G87 A;  3E34 B;  1N95 B;  4D4C A;  1LXM A;  4JJJ A;  4DI5 A;  1GA2 A;  3P5R A;  5EAT A;  1J0N A;  3M00 A;  1O79 A;  3WKG A;  3W7W A;  4AYQ A;  3SDQ A;  2H6I B;  4CE7 A;  2CQS A;  3W7S A;  3DSS B;  2EAC A;  1H39 A;  3Q73 B;  1RWG A;  3A0O A;  1RWA A;  4BOJ A;  2A73 B;  2SQC A;  3KLS A;  1HXC A;  3E30 B;  3W7U A;  3G6J B;  4DOE A;  2FBA A;  3M75 A;  1HZF A;  3EQA A;  1KKT A;  2FV0 A;  3G4F A;  3M72 A;  3G4D A;  3H3K A;  3WC3 A;  3E80 A;  5GW7 A;  1QQF A;  5IKH A;  2XQW A;  1H3B A;  4OZW A;  4EL8 A;  1FBW A;  4E1Y A;  1N7Q A;  1KRE A;  3E33 B;  1GSZ A;  5IK9 A;  4J5T A;  1H54 A;  2XFG A;  2WII B;  1LD8 B;  2X03 A;  3TF4 A;  5ILD A;  5ILJ A;  2ONH A;  4MU9 A;  2RI8 A;  1X1I A;  1S64 B;  5ILZ A;  1N1Z A;  3SDU A;  2H6F B;  3EZ8 A;  1UT9 A;  2B39 A;  1X1H A;  3Q78 B;  1TNZ B;  1R76 A;  3VSN A;  4OK4 A;  5ILY A;  2A8Z A;  4GTT B;  1WU5 A;  1IA6 A;  3WKH A;  2B4F A;  1HXG A;  4F10 A;  3K11 A;  1FBO A;  1V5C A;  3DSV B;  3GT5 A;  1UG9 A;  2BRV X;  1GAH A;  4D4B A;  1OJO A;  2G02 A;  1F9G A;  1DCE B;  3E73 A;  1KRF A;  1SA4 B;  2WCO A;  3NFV A;  5M7I A;  4OK2 A;  3S4B A;  4ZRP A;  3RRS A;  1LD7 B;  3DST B;  3M7C A;  2ONG A;  2RI9 A;  3M71 A;  4XUV A;  2WYN A;  3WUX A;  4C1S A;  4Z4L A;  1QSJ A;  3QFZ A;  1RWF A;  3ACT A;  1C3D A;  5ILK A;  3C72 B;  1W6J A;  5ILI A;  1WU4 A;  1VD5 A;  3Q7A B;  1O6Q A;  3HXB B;  1FP3 A;  4EHM B;  4GAX A;  4DOD A;  2BRW A;  1JCS B;  1O1S B;  4ZH1 A;  1RWC A;  4L0G A;  1TNO B;  3M74 A;  3H7L A;  4ZH5 A;  1N20 A;  5DHK A;  3CIH A;  1HMW A;  1KS8 A;  1SQC A;  4GTQ B;  1JCR B;  1OJP A;  1H35 A;  4AYR A;  3M7L A;  3PZ4 B;  4LNB B;  4KTR A;  2WDA A;  2V3N A;  2JG0 A;  1KZO B;  4GTP B;  4F13 A;  1G9G A;  3E7J A;  3RJ3 A;  3RX7 A;  3S4A A;  1HM2 A;  2ZIR B;  4L6X A;  5GZK A;  5IK0 A;  2PN5 A;  1GXM A;  1WZZ A;  4M76 A;  4MBG B;  4CJ1 A;  3Q79 B;  2ZBL A;  1JS4 A;  1X1J A;  3QXQ A;  2WY8 A;  2RGK A;  1GXN A;  1O5M B;  2FUQ A;  2NOJ A;  2WY7 A;  5DHI A;  3RSY A;  4D94 A;  5FO7 B;  1N7O A;  1N4S B;  5ILH A;  1QBQ B;  1HX9 A;  1XWQ A;  1F9D A;  4FXG B;  1N21 A;  3SDT A;  3QFY A;  4ZRQ A;  3ON6 A;  4LIX A;  5E2J A;  1H3C A;  1FAE A;  3SDV A;  5KKB A;  3GLY A;  4AYO A;  5CA3 A;  2ZIS B;  1N1B A;  1QAZ A;  5IL8 A;  1TN6 B;  3M77 A;  1FMI A;  3HXE B;  3LZ9 A;  4FUS A;  4TXT A;  3OED A;  3AFJ A;  3DSW B;  1H3A A;  3REN A;  2H6H B;  3RX5 A;  4WVA A;  1TF4 A;  2V3P A;  1V5D A;  2J5C A;  3PYB A;  1W3Y A;  5IM1 A;  1EGU A;  3VSM A;  2BB6 A;  2DRQ A;  1V7W A;  4KKJ A;  2P0V A;  1O6H A;  3K7X A;  3SQC A;  3PZ3 B;  1H14 A;  1N22 A;  4OZV A;  1TNU B;  4Z4J A;  3S4D A;  3HXF B;  3P5P A;  2AFA A;  3QT9 A;  4GTS B;  3WIR A;  1AYX A;  3N0G A;  1V7X A;  4YDE B;  1IS9 A;  2FV1 A;  1FT1 B;  1NXC A;  2CQT A;  4KKI A;  2GH4 A;  2WIN B;  3M73 A;  2DRR A;  3EU8 A;  1N24 A;  1F9O A;  1H12 A;  1RW9 A;  4YDO B;  5FO9 B;  1G9J A;  2JJB A;  3M7E A;  3OXU A;  4WU0 A;  3D5R A;  3QPF A;  4MMH A;  2EAE A;  3D3I A;  5IK6 A;  2PMV A;  2E24 A;  1HMU A;  1HXA A;  4BOK A;  3VW5 A;  1NI1 B;  3M78 A;  5FO8 B;  2D8L A;  2BED B;  2V8I A;  2AHG A;  4V1R A; 
#chains in the Genus database with same CATH homology
 2ZZR A;  3X17 A;  2H6G B;  3E37 B;  3QXF A;  1LF9 A;  3T33 A;  1TN8 B;  3SAE A;  1LTX B;  3W5N A;  3VXD A;  3QG0 A;  4ZG8 A;  4FXK B;  3W5M A;  3E32 B;  1H13 A;  1GAI A;  2NVP A;  3M76 A;  3HXD B;  2DRO A;  2VN7 A;  1FO3 A;  3WKF A;  1N4Q B;  3WKI A;  3A3V A;  5M7Y A;  5MEH A;  1N4R B;  3QWT A;  1KWF A;  3PYA A;  5DGQ A;  1NL4 B;  3SFX B;  2D5J A;  3EUV B;  1FO2 A;  3SFY B;  3KSQ B;  1WU6 A;  4GL3 A;  4GTV B;  3D5S A;  2EAD A;  3PMM A;  5JPN B;  1L2A A;  3QT3 A;  1FCE A;  2BBC A;  2YIK A;  2I07 B;  4GTM B;  3SDR A;  1V7V A;  1UMP A;  3W7X A;  1ULV A;  3GZK A;  1K72 A;  3WIW A;  3RX8 A;  1O6R A;  3EU5 B;  4YCR A;  1RQ5 A;  3KSL B;  3KQ4 A;  3PZ1 B;  2OKX A;  4LNG B;  1S63 B;  1TNY B;  4Q88 A;  2F0Y B;  5CD2 A;  2XWB B;  2G0D A;  1XW2 A;  3ACS A;  1LF6 A;  5FOB B;  4Q2B A;  3HXC B;  3E6U A;  1H37 A;  2FUZ A;  3QSP A;  2V8K A;  1X9D A;  1KFG A;  1HCU A;  3M7B A;  4ONT A;  2Z07 A;  1D8D B;  1KZP B;  4D4D A;  4V1S A;  2DRS A;  3DSU B;  2V8J A;  3H2W A;  3P2C A;  1JCQ B;  3QRY A;  1DOG A;  3S4C A;  4QT9 A;  1XWT A;  2GZ6 A;  1MZC B;  1KSD A;  1CLC A;  4LNV A;  4D4A A;  1SA5 B;  4L9P B;  3Q75 B;  1W6K A;  3QDE A;  1G6I A;  1H36 A;  1CEM A;  4KTP A;  5CZL A;  4WVB A;  3DRA B;  3ANJ A;  5GY3 A;  1KSC A;  5JPM B;  1FPP B;  3ANI A;  1D8E B;  2IEJ B;  1GHQ A;  1N9A B;  1O1T B;  2VN4 A;  5DGR A;  3Q7F B;  4CJ0 A;  1FT2 B;  3CU7 A;  3DSX B;  1N94 B;  2XWJ B;  3S9V A;  1X81 B;  2R2L B;  2BB5 A;  3ANK A;  1AGM A;  1TNB B;  4TF4 A;  2F6D A;  5AGD A;  1L1Y A;  3WIQ A;  2AHF A;  3W7T A;  4GTR B;  4GTO B;  2QNO A;  1O1R B;  1NC5 A;  3PZ2 B;  4AYP A;  1N4P B;  1GLM A;  1GXO A;  2EAB A;  4WVC A;  2GOX A;  1DL2 A;  1TN7 B;  1IA7 A;  3DPY B;  2JF4 A;  1G87 A;  3E34 B;  1N95 B;  4D4C A;  4JJJ A;  1GA2 A;  3P5R A;  1O79 A;  3WKG A;  3W7W A;  4AYQ A;  3SDQ A;  2H6I B;  4CE7 A;  2CQS A;  3W7S A;  3DSS B;  2EAC A;  1H39 A;  3Q73 B;  4BOJ A;  2A73 B;  2SQC A;  3KLS A;  3E30 B;  3W7U A;  3G6J B;  4DOE A;  2FBA A;  3M75 A;  1HZF A;  3EQA A;  1KKT A;  2FV0 A;  3M72 A;  3H3K A;  3WC3 A;  5GW7 A;  1QQF A;  2XQW A;  1H3B A;  4EL8 A;  1FBW A;  1KRE A;  3E33 B;  1GSZ A;  4J5T A;  1H54 A;  2XFG A;  2WII B;  1LD8 B;  3TF4 A;  4MU9 A;  2RI8 A;  1S64 B;  3SDU A;  2H6F B;  3EZ8 A;  1UT9 A;  2B39 A;  3Q78 B;  1TNZ B;  1R76 A;  2A8Z A;  4GTT B;  1WU5 A;  1IA6 A;  3WKH A;  2B4F A;  3K11 A;  1FBO A;  1V5C A;  3DSV B;  3GT5 A;  1UG9 A;  1GAH A;  4D4B A;  2G02 A;  1DCE B;  3E73 A;  1KRF A;  1SA4 B;  5M7I A;  3S4B A;  4ZRP A;  3RRS A;  1LD7 B;  3DST B;  3M7C A;  2RI9 A;  3M71 A;  4XUV A;  2WYN A;  3WUX A;  4C1S A;  4Z4L A;  1QSJ A;  3QFZ A;  3ACT A;  1C3D A;  3C72 B;  1W6J A;  1WU4 A;  1VD5 A;  3Q7A B;  1O6Q A;  3HXB B;  1FP3 A;  4EHM B;  4DOD A;  1JCS B;  1O1S B;  4ZH1 A;  4L0G A;  1TNO B;  3M74 A;  3H7L A;  4ZH5 A;  3CIH A;  1KS8 A;  1SQC A;  4GTQ B;  1JCR B;  1H35 A;  4AYR A;  3M7L A;  3PZ4 B;  4LNB B;  4KTR A;  2V3N A;  2JG0 A;  1KZO B;  4GTP B;  1G9G A;  3RJ3 A;  3RX7 A;  3S4A A;  2ZIR B;  4L6X A;  5GZK A;  2PN5 A;  1GXM A;  1WZZ A;  4M76 A;  4MBG B;  4CJ1 A;  3Q79 B;  2ZBL A;  1JS4 A;  3QXQ A;  2WY8 A;  2RGK A;  1GXN A;  1O5M B;  2NOJ A;  2WY7 A;  3RSY A;  4D94 A;  5FO7 B;  1N4S B;  1QBQ B;  1XWQ A;  1F9D A;  4FXG B;  3SDT A;  3QFY A;  4ZRQ A;  3ON6 A;  4LIX A;  5E2J A;  1H3C A;  1FAE A;  3SDV A;  5KKB A;  3GLY A;  4AYO A;  5CA3 A;  2ZIS B;  1TN6 B;  3M77 A;  1FMI A;  3HXE B;  4FUS A;  4TXT A;  3OED A;  3AFJ A;  1H3A A;  3DSW B;  3REN A;  2H6H B;  3RX5 A;  4WVA A;  1TF4 A;  2V3P A;  1V5D A;  3PYB A;  2BB6 A;  2DRQ A;  1V7W A;  4KKJ A;  2P0V A;  1O6H A;  3K7X A;  3SQC A;  3PZ3 B;  1H14 A;  1TNU B;  4Z4J A;  3S4D A;  3HXF B;  3P5P A;  2AFA A;  3QT9 A;  4GTS B;  3WIR A;  1AYX A;  1V7X A;  4YDE B;  1IS9 A;  2FV1 A;  1FT1 B;  1NXC A;  2CQT A;  4KKI A;  2GH4 A;  2WIN B;  3M73 A;  2DRR A;  3EU8 A;  1F9O A;  1H12 A;  4YDO B;  5FO9 B;  1G9J A;  2JJB A;  3M7E A;  3OXU A;  4WU0 A;  3D5R A;  3QPF A;  2EAE A;  3D3I A;  2PMV A;  4BOK A;  3VW5 A;  1NI1 B;  3M78 A;  5FO8 B;  2D8L A;  2BED B;  2V8I A;  2AHG A;  4V1R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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