1GSZA

Crystal structure of a squalene cyclase in complex with the potential anticholesteremic drug ro48-8071
Total Genus 230
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
230
sequence length
619
structure length
619
Chain Sequence
AYARTLDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDRDRMEKIRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEEPMQKALRFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSWARATVVALSIVMSRQPVFPLPERARVPELYETDVPPRRRGAKGGGGWIFDALDRALHGYQKLSVHPFRRAAEIRALDWLLERQAGDGSWGGIQPPWFYALIALKILDMTQHPAFIKGWEGLELYGVELDYGGWMFQASISPVWDTGLAVLALRAAGLPADHDRLVKAGEWLLDRQITVPGDWAVKRPNLKPGGFAFQFDNVYYPDVDDTAVVVWALNTLRLPDERRRRDAMTKGFRWIVGMQSSNGGWGAYDVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSFGYDDAWKVIRRAVEYLKREQKPDGSWFGRWGVNYLYGTGAVVSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSYEDPAYAGKGASTPSQTAWALMALIAGGRAESEAARRGVQYLVETQRPDGGWDEPYYTGTGFPGDFYLGYTMYRHVFPTLALGRYKQAI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase
molecule keywords SQUALENE--HOPENE CYCLASE
publication title Crystal Structure of a Squalene Cyclase in Complex with the Potential Anticholesteremic Drug Ro48-8071
pubmed doi rcsb
source organism Alicyclobacillus acidocaldarius
total genus 230
structure length 619
sequence length 619
chains with identical sequence B, C
ec nomenclature ec 4.2.1.129: Squalene--hopanol cyclase.
pdb deposition date 2002-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
A PF13243 SQHop_cyclase_C Squalene-hopene cyclase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1gszA01
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1gszA02
1D8DB 2BB5A 1N95B 3E30B 2G02A 3KSQB 2XQWA 3PZ2B 4FXKB 1R76A 1O5MB 1QSJA 1S64B 2SQCA 3E33B 3HXCB 4YDOB 1KZPB 3C72B 5JPMB 2F0YB 4MBGB 1GXOA 4M76A 1H36A 1QBQB 3OEDA 1N4QB 1S63B 1GHQA 2A73B 3Q78B 4YDEB 3PZ4B 3SQCA 2ZISB 1W6JA 3DSWB 1FT1B 3PZ1B 5FO9B 2PMVA 1N4RB 4ZRQA 4GTRB 4V1RA 1H35A 1KZOB 1GSZA 4GTSB 1O1SB 4C1SA 1SA5B 2XWBB 1TNBB 3K7XA 3OXUA 4KKIA 4D4CA 1N9AB 4D4DA 3Q75B 1H39A 3Q7FB 2WINB 1TNOB 4GTVB 1GXMA 1NI1B 3HXBB 4ONTA 4ZRPA 1O6HA 4ZH1A 1TN8B 1O79A 2IEJB 2BEDB 3KSLB 3DPYB 4BOKA 1TN6B 4LNBB 3KQ4A 2V3PA 3EU5B 1LD8B 1SA4B 1O6QA 3DSUB 1LTXB 4D4BA 1FT2B 3RJ3A 1X81B 2H6HB 1O1TB 1NL4B 1MZCB 1JCSB 3D5RA 3DSTB 3PZ3B 1TNUB 1TNYB 2H6IB 4KKJA 5AGDA 1C3DA 1UMPA 1N4PB 2WY7A 4LNVA 1HZFA 3Q7AB 2H6GB 1H3BA 1TN7B 1N94B 2PN5A 3HXDB 3DSSB 4FXGB 1W6KA 4GTQB 1FPPB 1QQFA 4GTTB 2NOJA 1DCEB 2WY8A 3EUVB 4L9PB 2V8IA 2I07B 2WIIB 1N4SB 3E37B 4D4AA 3G6JB 4GTMB 2BB6A 1H3CA 1O1RB 1TNZB 2R2LB 3D5SA 5JPNB 1H3AA 4GTPB 2G0DA 5FOBB 3HXEB 3SFYB 3Q79B 4GTOB 4D94A 3DRAB 1GXNA 1H37A 2XWJB 3E34B 4V1SA 2GOXA 5FO7B 5FO8B 1D8EB 1LD7B 1JCQB 2BBCA 4MU9A 3SFXB 3E32B 3KLSA 2V8KA 3HXFB 3DSXB 3CU7A 2H6FB 2V3NA 3Q73B 4LNGB 4EHMB 2B39A 4BOJA 1O6RA 1SQCA 2V8JA 3DSVB 1JCRB 2ZIRB
chains in the Genus database with same CATH superfamily
2XQWA 2J5CA 3E73A 2B4FA 3EU8A 1IS9A 4Q2BA 1R76A 2GH4A 3NNBA 1O5MB 2SQCA 1S64B 3E33B 3QFYA 4GAXA 1H36A 2WCOA 3RRSA 1V7VA 2ONHA 2ZISB 1N7QA 1IA7A 1KFGA 3PZ1B 5FO9B 1N4RB 3H3KA 3S4BA 3QDEA 4WVAA 1KZOB 2E22A 1O1SB 3K7XA 1J0MA 3OXUA 1LOHA 3M00A 4D4CA 1RWHA 3Q75B 4ONTA 4JJJA 3SDVA 3P5PA 2BEDB 1J0NA 1AYXA 2QNOA 3VXDA 3PMMA 3EU5B 1LD8B 2DRRA 1LTXB 3G4DA 4F13A 1V7XA 4DOEA 1X81B 5IK9A 2A8ZA 3D5RA 3QPFA 3LZ9A 3N0GA 2FUTA 4KTRA 5IL8A 2H6IB 5AGDA 4OZWA 4QT9A 1WU4A 4MMHA 1HZFA 1HV6A 5IK6A 1N7OA 4FXGB 3QT3A 1QQFA 4GTTB 1H13A 5GZKA 1DCEB 1N20A 2WY8A 3EUVB 4OK2A 4E1YA 1FBOA 3SAEA 1W3YA 4AYOA 3E37B 5DHKA 3G6JB 4GTMB 1KSDA 5CZLA 3G4FA 1O1RB 1TNZB 3D5SA 1GLMA 3H7LA 4CJ1A 1N7PA 1H3AA 4GTPB 1ULVA 3EQAA 4GTOB 1GXNA 1H37A 2XWJB 1D8EB 3W5MA 5IM1A 2FV1A 3ACTA 3KLSA 3P5RA 2V8KA 3E7JA 2EAEA 3W7TA 4BOJA 1O6RA 2V8JA 3DSVB 1JCRB 2ZIRB 2RI8A 3KSQB 1RWGA 1F9DA 3S4AA 5DHIA 3W7WA 1QSJA 4YDOB 1KZPB 3AFLA 3C72B 4WU0A 1N1ZA 4MBGB 4M76A 1AGMA 1N4QB 1S63B 1GHQA 2A73B 5M7YA 2OKXA 1FT1B 1OJOA 1EGUA 3M01A 5E2JA 4ZRQA 2JJBA 4V1RA 1SA5B 2XWBB 1KSCA 1HN0A 1N23A 3WKHA 3M74A 1X1JA 1FP3A 1X1IA 3Q7FB 1HXCA 2BRWA 2P0VA 1RQ5A 2CQTA 1O6HA 1X9DA 2XFGA 1FO2A 3M77A 1DL2A 1KS8A 4LNBB 3QWTA 2Q1FA 1CLCA 1FT2B 5GY3A 2BRPA 1O1TB 5IKAA 2DRQA 1JCSB 1MZCB 1G87A 1G9GA 1KREA 3DSTB 3WIRA 2NVPA 1H12A 4KKJA 3SDTA 1C3DA 5ILZA 1OJPA 3S9VA 1V5DA 5ILDA 3ACSA 2PN5A 3X17A 3HXDB 3M7CA 5ILIA 1N1BA 2RGKA 3RX8A 4Z4JA 2NOJA 3ANKA 3E80A 3K11A 1FBWA 2D5JA 5JMDA 1DOGA 5ILKA 1X1HA 1G9JA 2WIIB 4J5TA 5C05A 3WKGA 1I8QA 4OK4A 5CD2A 1RW9A 5JPNB 3A3VA 2AFAA 4WVCA 4D94A 1V7WA 3E34B 5FO7B 1GA2A 2BBCA 3SFXB 1HXAA 3M72A 3A0OA 4EHMB 3QG0A 1SQCA 1LXKA 2E24A 4NEIA 2BB5A 1N95B 4AYRA 3WKFA 3PZ2B 3M73A 3QXQA 3HXCB 1FMIA 3RX5A 3ON6A 2ZZRA 1QBQB 5EAUA 3M71A 3GT5A 3Q78B 4YDEB 3PZ4B 1W6JA 2RI9A 1OJMA 2PMVA 2AHFA 3S4DA 1H35A 4GTSB 4C1SA 1RWFA 2D8LA 3WC3A 1N21A 5EATA 4KKIA 1N9AB 5GW7A 2ZBLA 4AYQA 1XWQA 5IKHA 2X03A 1XWTA 1NI1B 2JG0A 1IA6A 2ONGA 4ZH1A 1TN8B 1O79A 3WIWA 4FNVA 2IEJB 3E6UA 3KSLB 2WDAA 1TN6B 1LF9A 2EABA 1WZZA 1F1SA 1FAEA 5EASA 3KQ4A 4EL8A 5JMFA 1N7NA 3DSUB 1O6QA 3M75A 3D3IA 4WVBA 3NFVA 2GZ6A 3M78A 1NXCA 5KKBA 3PZ3B 1TNUB 1TNYB 1HXGA 5IK0A 1N4PB 4LNVA 5ILYA 3VSMA 1H3BA 1TN7B 2DROA 1LXMA 3M02A 1VD5A 3M7EA 4KTPA 3SDUA 5M7IA 4LIXA 1KKTA 3AFJA 3WIQA 3QSPA 1V5CA 2JF4A 2V8IA 2YIKA 2I07B 2DRSA 4FJQA 4XUVA 3QXFA 3QT9A 2BRVX 3SDQA 1L1YA 1HMUA 1H3CA 2EADA 1F9OA 2R2LB 4ZH5A 3VSNA 1RWCA 3P2CA 5IL3A 1NC5A 5FOBB 3W7SA 3HXEB 1RWAA 4RNQA 3SFYB 3Q79B 2FUQA 4DODA 1H54A 3DRAB 1HCUA 1LD7B 2AHGA 2EACA 4LNGB 3RX7A 2B39A 1N22A 3ANJA 1H14A 3H2WA 1HX9A 3WUXA 1D8DB 3E30B 2G02A 4MMIA 4FXKB 4TF4A 1TF4A 5JPMB 2F0YB 1JS4A 1GXOA 1LF6A 3OEDA 3VW5A 4FUSA 5ILJA 3SQCA 3DSWB 4DI5A 3RSYA 5CA3A 1HMWA 1FCEA 1CEMA 3PYBA 4GTRB 1GSZA 1N24A 5DGQA 1UG9A 4Z4LA 4L6XA 3WKIA 1TNBB 2Z07A 3GZKA 1G6IA 3CIHA 2VN7A 4D4DA 1H39A 4Q88A 2WINB 1TNOB 4GTVB 4OJZA 1GXMA 4ZRPA 3HXBB 3TF4A 3DPYB 3N0FA 4BOKA 1K72A 4YCRA 3W5NA 2WYNA 2V3PA 1SA4B 4D4BA 1HM3A 1KRFA 5MEHA 3RJ3A 2H6HB 1NL4B 1WU5A 3ANIA 3M7BA 4L0GA 3W7XA 5ILHA 1UMPA 2F6DA 2WY7A 3Q7AB 2H6GB 1C82A 5DGRA 1CB8A 1QAZA 1N94B 3DSSB 3GLYA 3RENA 1W6KA 3W7UA 4AYPA 3M76A 4GTQB 1UT9A 1FPPB 4CE7A 3QFZA 3S4CA 1FO3A 1OJNA 3PYAA 4L9PB 4OZVA 1KWFA 1N4SB 4D4AA 4TXTA 3T33A 2BB6A 3QRYA 3M7LA 1GAIA 1F9GA 2G0DA 4GL3A 1WU6A 4ZG8A 1XW2A 1GAHA 2FUZA 4V1SA 2GOXA 3EZ8A 5FO8B 1N7RA 1JCQB 4CJ0A 4MU9A 2VN4A 3E32B 3HXFB 1HM2A 3SDRA 2FBAA 3DSXB 4F10A 3CU7A 2H6FB 2V3NA 3Q73B 2CQSA 1L2AA 2FV0A
chains in the Genus database with same CATH topology
2XQWA 3E73A 2B4FA 3EU8A 1IS9A 4Q2BA 1R76A 2GH4A 1O5MB 2SQCA 1S64B 3E33B 3QFYA 1H36A 3RRSA 1V7VA 2ZISB 1IA7A 1KFGA 3PZ1B 5FO9B 1N4RB 3H3KA 3S4BA 3QDEA 4WVAA 1KZOB 1O1SB 3K7XA 3OXUA 4D4CA 3Q75B 4ONTA 4JJJA 3SDVA 3P5PA 2BEDB 1AYXA 2QNOA 3VXDA 3PMMA 3EU5B 1LD8B 2DRRA 1LTXB 1V7XA 4DOEA 1X81B 2A8ZA 3QPFA 3D5RA 4KTRA 2H6IB 5AGDA 4QT9A 1WU4A 1HZFA 4FXGB 3QT3A 1QQFA 4GTTB 1H13A 5GZKA 1DCEB 2WY8A 3EUVB 1FBOA 3SAEA 4AYOA 3E37B 3G6JB 4GTMB 1KSDA 5CZLA 1O1RB 1TNZB 3D5SA 1GLMA 3H7LA 4CJ1A 1H3AA 4GTPB 1ULVA 3EQAA 4GTOB 1GXNA 1H37A 2XWJB 1D8EB 3W5MA 2FV1A 3ACTA 3KLSA 3P5RA 2V8KA 2EAEA 3W7TA 4BOJA 1O6RA 2V8JA 3DSVB 1JCRB 2ZIRB 2RI8A 3KSQB 1F9DA 3S4AA 3W7WA 1QSJA 4YDOB 1KZPB 3C72B 4WU0A 4MBGB 4M76A 1AGMA 1N4QB 1S63B 1GHQA 2A73B 5M7YA 2OKXA 1FT1B 5E2JA 4ZRQA 2JJBA 4V1RA 1SA5B 2XWBB 1KSCA 3WKHA 3M74A 1FP3A 3Q7FB 2P0VA 1RQ5A 2CQTA 1O6HA 1X9DA 2XFGA 1FO2A 3M77A 1DL2A 1KS8A 4LNBB 3QWTA 1CLCA 1FT2B 5GY3A 1O1TB 2DRQA 1MZCB 1JCSB 1G87A 1G9GA 1KREA 3DSTB 3WIRA 2NVPA 1H12A 4KKJA 3SDTA 1C3DA 3S9VA 1V5DA 3ACSA 2PN5A 3X17A 3HXDB 3M7CA 2RGKA 3RX8A 4Z4JA 2NOJA 3ANKA 3K11A 1FBWA 2D5JA 1DOGA 1G9JA 2WIIB 4J5TA 3WKGA 5CD2A 5JPNB 3A3VA 2AFAA 4WVCA 4D94A 1V7WA 3E34B 5FO7B 1GA2A 2BBCA 3SFXB 3M72A 4EHMB 3QG0A 1SQCA 2BB5A 1N95B 4AYRA 3WKFA 3PZ2B 3M73A 3QXQA 3HXCB 1FMIA 3RX5A 3ON6A 2ZZRA 1QBQB 3M71A 3GT5A 3Q78B 4YDEB 3PZ4B 1W6JA 2RI9A 2PMVA 2AHFA 3S4DA 1H35A 4GTSB 4C1SA 2D8LA 3WC3A 4KKIA 1N9AB 5GW7A 2ZBLA 4AYQA 1XWQA 1XWTA 1NI1B 2JG0A 1IA6A 4ZH1A 1TN8B 1O79A 3WIWA 2IEJB 3E6UA 3KSLB 1TN6B 1LF9A 2EABA 1WZZA 1FAEA 3KQ4A 4EL8A 3DSUB 1O6QA 3M75A 3D3IA 4WVBA 2GZ6A 3M78A 1NXCA 5KKBA 3PZ3B 1TNUB 1TNYB 1N4PB 4LNVA 1H3BA 1TN7B 2DROA 1VD5A 3M7EA 4KTPA 3SDUA 5M7IA 4LIXA 1KKTA 3AFJA 3WIQA 3QSPA 1V5CA 2JF4A 2V8IA 2YIKA 2I07B 2DRSA 4XUVA 3QXFA 3QT9A 3SDQA 1L1YA 1H3CA 2EADA 1F9OA 2R2LB 4ZH5A 3P2CA 1NC5A 5FOBB 3W7SA 3HXEB 3SFYB 3Q79B 4DODA 1H54A 3DRAB 1HCUA 1LD7B 2AHGA 2EACA 4LNGB 3RX7A 2B39A 3ANJA 1H14A 3H2WA 3WUXA 1D8DB 3E30B 2G02A 4FXKB 4TF4A 1TF4A 5JPMB 2F0YB 1JS4A 1GXOA 1LF6A 3OEDA 3VW5A 4FUSA 3SQCA 3DSWB 3RSYA 5CA3A 1FCEA 1CEMA 3PYBA 4GTRB 1GSZA 5DGQA 1UG9A 4Z4LA 4L6XA 3WKIA 1TNBB 2Z07A 3GZKA 1G6IA 3CIHA 2VN7A 4D4DA 1H39A 4Q88A 2WINB 1TNOB 4GTVB 3TF4A 1GXMA 4ZRPA 3HXBB 3DPYB 4BOKA 1K72A 4YCRA 3W5NA 2WYNA 2V3PA 1SA4B 4D4BA 1KRFA 5MEHA 3RJ3A 2H6HB 1NL4B 1WU5A 3ANIA 3M7BA 4L0GA 3W7XA 1UMPA 2F6DA 2WY7A 3Q7AB 2H6GB 5DGRA 1N94B 3DSSB 3GLYA 3RENA 1W6KA 3W7UA 4AYPA 3M76A 4GTQB 1UT9A 1FPPB 4CE7A 3QFZA 3S4CA 1FO3A 3PYAA 4L9PB 1KWFA 1N4SB 4D4AA 4TXTA 3T33A 2BB6A 3QRYA 3M7LA 1GAIA 2G0DA 4GL3A 1WU6A 4ZG8A 1XW2A 1GAHA 2FUZA 4V1SA 2GOXA 3EZ8A 5FO8B 1JCQB 4CJ0A 4MU9A 2VN4A 3E32B 3HXFB 3SDRA 2FBAA 3DSXB 3CU7A 2H6FB 2V3NA 3Q73B 2CQSA 1L2AA 2FV0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D8D B;  2BB5 A;  1N95 B;  3E30 B;  2G02 A;  3KSQ B;  2XQW A;  3PZ2 B;  4FXK B;  1R76 A;  1O5M B;  1QSJ A;  1S64 B;  2SQC A;  3E33 B;  3HXC B;  4YDO B;  1KZP B;  3C72 B;  5JPM B;  2F0Y B;  4MBG B;  1GXO A;  4M76 A;  1H36 A;  1QBQ B;  3OED A;  1N4Q B;  1S63 B;  1GHQ A;  2A73 B;  3Q78 B;  4YDE B;  3PZ4 B;  3SQC A;  2ZIS B;  1W6J A;  3DSW B;  1FT1 B;  3PZ1 B;  5FO9 B;  2PMV A;  1N4R B;  4ZRQ A;  4GTR B;  4V1R A;  1H35 A;  1KZO B;  1GSZ A;  4GTS B;  1O1S B;  4C1S A;  1SA5 B;  2XWB B;  1TNB B;  3K7X A;  3OXU A;  4KKI A;  4D4C A;  1N9A B;  4D4D A;  3Q75 B;  1H39 A;  3Q7F B;  2WIN B;  1TNO B;  4GTV B;  1GXM A;  1NI1 B;  3HXB B;  4ONT A;  4ZRP A;  1O6H A;  4ZH1 A;  1TN8 B;  1O79 A;  2IEJ B;  2BED B;  3KSL B;  3DPY B;  4BOK A;  1TN6 B;  4LNB B;  3KQ4 A;  2V3P A;  3EU5 B;  1LD8 B;  1SA4 B;  1O6Q A;  3DSU B;  1LTX B;  4D4B A;  1FT2 B;  3RJ3 A;  1X81 B;  2H6H B;  1O1T B;  1NL4 B;  1MZC B;  1JCS B;  3D5R A;  3DST B;  3PZ3 B;  1TNU B;  1TNY B;  2H6I B;  4KKJ A;  5AGD A;  1C3D A;  1UMP A;  1N4P B;  2WY7 A;  4LNV A;  1HZF A;  3Q7A B;  2H6G B;  1H3B A;  1TN7 B;  1N94 B;  2PN5 A;  3HXD B;  3DSS B;  4FXG B;  1W6K A;  4GTQ B;  1FPP B;  1QQF A;  4GTT B;  2NOJ A;  1DCE B;  2WY8 A;  3EUV B;  4L9P B;  2V8I A;  2I07 B;  2WII B;  1N4S B;  3E37 B;  4D4A A;  3G6J B;  4GTM B;  2BB6 A;  1H3C A;  1O1R B;  1TNZ B;  2R2L B;  3D5S A;  5JPN B;  1H3A A;  4GTP B;  2G0D A;  5FOB B;  3HXE B;  3SFY B;  3Q79 B;  4GTO B;  4D94 A;  3DRA B;  1GXN A;  1H37 A;  2XWJ B;  3E34 B;  4V1S A;  2GOX A;  5FO7 B;  5FO8 B;  1D8E B;  1LD7 B;  1JCQ B;  2BBC A;  4MU9 A;  3SFX B;  3E32 B;  3KLS A;  2V8K A;  3HXF B;  3DSX B;  3CU7 A;  2H6F B;  2V3N A;  3Q73 B;  4LNG B;  4EHM B;  2B39 A;  4BOJ A;  1O6R A;  1SQC A;  2V8J A;  3DSV B;  1JCR B;  2ZIR B; 
#chains in the Genus database with same CATH topology
 2XQW A;  2J5C A;  3E73 A;  2B4F A;  3EU8 A;  1IS9 A;  4Q2B A;  1R76 A;  2GH4 A;  3NNB A;  1O5M B;  2SQC A;  1S64 B;  3E33 B;  3QFY A;  4GAX A;  1H36 A;  2WCO A;  3RRS A;  1V7V A;  2ONH A;  2ZIS B;  1N7Q A;  1IA7 A;  1KFG A;  3PZ1 B;  5FO9 B;  1N4R B;  3H3K A;  3S4B A;  3QDE A;  4WVA A;  1KZO B;  2E22 A;  1O1S B;  3K7X A;  1J0M A;  3OXU A;  1LOH A;  3M00 A;  4D4C A;  1RWH A;  3Q75 B;  4ONT A;  4JJJ A;  3SDV A;  3P5P A;  2BED B;  1J0N A;  1AYX A;  2QNO A;  3VXD A;  3PMM A;  3EU5 B;  1LD8 B;  2DRR A;  1LTX B;  3G4D A;  4F13 A;  1V7X A;  4DOE A;  1X81 B;  5IK9 A;  2A8Z A;  3D5R A;  3QPF A;  3LZ9 A;  3N0G A;  2FUT A;  4KTR A;  5IL8 A;  2H6I B;  5AGD A;  4OZW A;  4QT9 A;  1WU4 A;  4MMH A;  1HZF A;  1HV6 A;  5IK6 A;  1N7O A;  4FXG B;  3QT3 A;  1QQF A;  4GTT B;  1H13 A;  5GZK A;  1DCE B;  1N20 A;  2WY8 A;  3EUV B;  4OK2 A;  4E1Y A;  1FBO A;  3SAE A;  1W3Y A;  4AYO A;  3E37 B;  5DHK A;  3G6J B;  4GTM B;  1KSD A;  5CZL A;  3G4F A;  1O1R B;  1TNZ B;  3D5S A;  1GLM A;  3H7L A;  4CJ1 A;  1N7P A;  1H3A A;  4GTP B;  1ULV A;  3EQA A;  4GTO B;  1GXN A;  1H37 A;  2XWJ B;  1D8E B;  3W5M A;  5IM1 A;  2FV1 A;  3ACT A;  3KLS A;  3P5R A;  2V8K A;  3E7J A;  2EAE A;  3W7T A;  4BOJ A;  1O6R A;  2V8J A;  3DSV B;  1JCR B;  2ZIR B;  2RI8 A;  3KSQ B;  1RWG A;  1F9D A;  3S4A A;  5DHI A;  3W7W A;  1QSJ A;  4YDO B;  1KZP B;  3AFL A;  3C72 B;  4WU0 A;  1N1Z A;  4MBG B;  4M76 A;  1AGM A;  1N4Q B;  1S63 B;  1GHQ A;  2A73 B;  5M7Y A;  2OKX A;  1FT1 B;  1OJO A;  1EGU A;  3M01 A;  5E2J A;  4ZRQ A;  2JJB A;  4V1R A;  1SA5 B;  2XWB B;  1KSC A;  1HN0 A;  1N23 A;  3WKH A;  3M74 A;  1X1J A;  1FP3 A;  1X1I A;  3Q7F B;  1HXC A;  2BRW A;  2P0V A;  1RQ5 A;  2CQT A;  1O6H A;  1X9D A;  2XFG A;  1FO2 A;  3M77 A;  1DL2 A;  1KS8 A;  4LNB B;  3QWT A;  2Q1F A;  1CLC A;  1FT2 B;  5GY3 A;  2BRP A;  1O1T B;  5IKA A;  2DRQ A;  1JCS B;  1MZC B;  1G87 A;  1G9G A;  1KRE A;  3DST B;  3WIR A;  2NVP A;  1H12 A;  4KKJ A;  3SDT A;  1C3D A;  5ILZ A;  1OJP A;  3S9V A;  1V5D A;  5ILD A;  3ACS A;  2PN5 A;  3X17 A;  3HXD B;  3M7C A;  5ILI A;  1N1B A;  2RGK A;  3RX8 A;  4Z4J A;  2NOJ A;  3ANK A;  3E80 A;  3K11 A;  1FBW A;  2D5J A;  5JMD A;  1DOG A;  5ILK A;  1X1H A;  1G9J A;  2WII B;  4J5T A;  5C05 A;  3WKG A;  1I8Q A;  4OK4 A;  5CD2 A;  1RW9 A;  5JPN B;  3A3V A;  2AFA A;  4WVC A;  4D94 A;  1V7W A;  3E34 B;  5FO7 B;  1GA2 A;  2BBC A;  3SFX B;  1HXA A;  3M72 A;  3A0O A;  4EHM B;  3QG0 A;  1SQC A;  1LXK A;  2E24 A;  4NEI A;  2BB5 A;  1N95 B;  4AYR A;  3WKF A;  3PZ2 B;  3M73 A;  3QXQ A;  3HXC B;  1FMI A;  3RX5 A;  3ON6 A;  2ZZR A;  1QBQ B;  5EAU A;  3M71 A;  3GT5 A;  3Q78 B;  4YDE B;  3PZ4 B;  1W6J A;  2RI9 A;  1OJM A;  2PMV A;  2AHF A;  3S4D A;  1H35 A;  4GTS B;  4C1S A;  1RWF A;  2D8L A;  3WC3 A;  1N21 A;  5EAT A;  4KKI A;  1N9A B;  5GW7 A;  2ZBL A;  4AYQ A;  1XWQ A;  5IKH A;  2X03 A;  1XWT A;  1NI1 B;  2JG0 A;  1IA6 A;  2ONG A;  4ZH1 A;  1TN8 B;  1O79 A;  3WIW A;  4FNV A;  2IEJ B;  3E6U A;  3KSL B;  2WDA A;  1TN6 B;  1LF9 A;  2EAB A;  1WZZ A;  1F1S A;  1FAE A;  5EAS A;  3KQ4 A;  4EL8 A;  5JMF A;  1N7N A;  3DSU B;  1O6Q A;  3M75 A;  3D3I A;  4WVB A;  3NFV A;  2GZ6 A;  3M78 A;  1NXC A;  5KKB A;  3PZ3 B;  1TNU B;  1TNY B;  1HXG A;  5IK0 A;  1N4P B;  4LNV A;  5ILY A;  3VSM A;  1H3B A;  1TN7 B;  2DRO A;  1LXM A;  3M02 A;  1VD5 A;  3M7E A;  4KTP A;  3SDU A;  5M7I A;  4LIX A;  1KKT A;  3AFJ A;  3WIQ A;  3QSP A;  1V5C A;  2JF4 A;  2V8I A;  2YIK A;  2I07 B;  2DRS A;  4FJQ A;  4XUV A;  3QXF A;  3QT9 A;  2BRV X;  3SDQ A;  1L1Y A;  1HMU A;  1H3C A;  2EAD A;  1F9O A;  2R2L B;  4ZH5 A;  3VSN A;  1RWC A;  3P2C A;  5IL3 A;  1NC5 A;  5FOB B;  3W7S A;  3HXE B;  1RWA A;  4RNQ A;  3SFY B;  3Q79 B;  2FUQ A;  4DOD A;  1H54 A;  3DRA B;  1HCU A;  1LD7 B;  2AHG A;  2EAC A;  4LNG B;  3RX7 A;  2B39 A;  1N22 A;  3ANJ A;  1H14 A;  3H2W A;  1HX9 A;  3WUX A;  1D8D B;  3E30 B;  2G02 A;  4MMI A;  4FXK B;  4TF4 A;  1TF4 A;  5JPM B;  2F0Y B;  1JS4 A;  1GXO A;  1LF6 A;  3OED A;  3VW5 A;  4FUS A;  5ILJ A;  3SQC A;  3DSW B;  4DI5 A;  3RSY A;  5CA3 A;  1HMW A;  1FCE A;  1CEM A;  3PYB A;  4GTR B;  1GSZ A;  1N24 A;  5DGQ A;  1UG9 A;  4Z4L A;  4L6X A;  3WKI A;  1TNB B;  2Z07 A;  3GZK A;  1G6I A;  3CIH A;  2VN7 A;  4D4D A;  1H39 A;  4Q88 A;  2WIN B;  1TNO B;  4GTV B;  4OJZ A;  1GXM A;  4ZRP A;  3HXB B;  3TF4 A;  3DPY B;  3N0F A;  4BOK A;  1K72 A;  4YCR A;  3W5N A;  2WYN A;  2V3P A;  1SA4 B;  4D4B A;  1HM3 A;  1KRF A;  5MEH A;  3RJ3 A;  2H6H B;  1NL4 B;  1WU5 A;  3ANI A;  3M7B A;  4L0G A;  3W7X A;  5ILH A;  1UMP A;  2F6D A;  2WY7 A;  3Q7A B;  2H6G B;  1C82 A;  5DGR A;  1CB8 A;  1QAZ A;  1N94 B;  3DSS B;  3GLY A;  3REN A;  1W6K A;  3W7U A;  4AYP A;  3M76 A;  4GTQ B;  1UT9 A;  1FPP B;  4CE7 A;  3QFZ A;  3S4C A;  1FO3 A;  1OJN A;  3PYA A;  4L9P B;  4OZV A;  1KWF A;  1N4S B;  4D4A A;  4TXT A;  3T33 A;  2BB6 A;  3QRY A;  3M7L A;  1GAI A;  1F9G A;  2G0D A;  4GL3 A;  1WU6 A;  4ZG8 A;  1XW2 A;  1GAH A;  2FUZ A;  4V1S A;  2GOX A;  3EZ8 A;  5FO8 B;  1N7R A;  1JCQ B;  4CJ0 A;  4MU9 A;  2VN4 A;  3E32 B;  3HXF B;  1HM2 A;  3SDR A;  2FBA A;  3DSX B;  4F10 A;  3CU7 A;  2H6F B;  2V3N A;  3Q73 B;  2CQS A;  1L2A A;  2FV0 A; 
#chains in the Genus database with same CATH homology
 2XQW A;  3E73 A;  2B4F A;  3EU8 A;  1IS9 A;  4Q2B A;  1R76 A;  2GH4 A;  1O5M B;  2SQC A;  1S64 B;  3E33 B;  3QFY A;  1H36 A;  3RRS A;  1V7V A;  2ZIS B;  1IA7 A;  1KFG A;  3PZ1 B;  5FO9 B;  1N4R B;  3H3K A;  3S4B A;  3QDE A;  4WVA A;  1KZO B;  1O1S B;  3K7X A;  3OXU A;  4D4C A;  3Q75 B;  4ONT A;  4JJJ A;  3SDV A;  3P5P A;  2BED B;  1AYX A;  2QNO A;  3VXD A;  3PMM A;  3EU5 B;  1LD8 B;  2DRR A;  1LTX B;  1V7X A;  4DOE A;  1X81 B;  2A8Z A;  3QPF A;  3D5R A;  4KTR A;  2H6I B;  5AGD A;  4QT9 A;  1WU4 A;  1HZF A;  4FXG B;  3QT3 A;  1QQF A;  4GTT B;  1H13 A;  5GZK A;  1DCE B;  2WY8 A;  3EUV B;  1FBO A;  3SAE A;  4AYO A;  3E37 B;  3G6J B;  4GTM B;  1KSD A;  5CZL A;  1O1R B;  1TNZ B;  3D5S A;  1GLM A;  3H7L A;  4CJ1 A;  1H3A A;  4GTP B;  1ULV A;  3EQA A;  4GTO B;  1GXN A;  1H37 A;  2XWJ B;  1D8E B;  3W5M A;  2FV1 A;  3ACT A;  3KLS A;  3P5R A;  2V8K A;  2EAE A;  3W7T A;  4BOJ A;  1O6R A;  2V8J A;  3DSV B;  1JCR B;  2ZIR B;  2RI8 A;  3KSQ B;  1F9D A;  3S4A A;  3W7W A;  1QSJ A;  4YDO B;  1KZP B;  3C72 B;  4WU0 A;  4MBG B;  4M76 A;  1AGM A;  1N4Q B;  1S63 B;  1GHQ A;  2A73 B;  5M7Y A;  2OKX A;  1FT1 B;  5E2J A;  4ZRQ A;  2JJB A;  4V1R A;  1SA5 B;  2XWB B;  1KSC A;  3WKH A;  3M74 A;  1FP3 A;  3Q7F B;  2P0V A;  1RQ5 A;  2CQT A;  1O6H A;  1X9D A;  2XFG A;  1FO2 A;  3M77 A;  1DL2 A;  1KS8 A;  4LNB B;  3QWT A;  1CLC A;  1FT2 B;  5GY3 A;  1O1T B;  2DRQ A;  1MZC B;  1JCS B;  1G87 A;  1G9G A;  1KRE A;  3DST B;  3WIR A;  2NVP A;  1H12 A;  4KKJ A;  3SDT A;  1C3D A;  3S9V A;  1V5D A;  3ACS A;  2PN5 A;  3X17 A;  3HXD B;  3M7C A;  2RGK A;  3RX8 A;  4Z4J A;  2NOJ A;  3ANK A;  3K11 A;  1FBW A;  2D5J A;  1DOG A;  1G9J A;  2WII B;  4J5T A;  3WKG A;  5CD2 A;  5JPN B;  3A3V A;  2AFA A;  4WVC A;  4D94 A;  1V7W A;  3E34 B;  5FO7 B;  1GA2 A;  2BBC A;  3SFX B;  3M72 A;  4EHM B;  3QG0 A;  1SQC A;  2BB5 A;  1N95 B;  4AYR A;  3WKF A;  3PZ2 B;  3M73 A;  3QXQ A;  3HXC B;  1FMI A;  3RX5 A;  3ON6 A;  2ZZR A;  1QBQ B;  3M71 A;  3GT5 A;  3Q78 B;  4YDE B;  3PZ4 B;  1W6J A;  2RI9 A;  2PMV A;  2AHF A;  3S4D A;  1H35 A;  4GTS B;  4C1S A;  2D8L A;  3WC3 A;  4KKI A;  1N9A B;  5GW7 A;  2ZBL A;  4AYQ A;  1XWQ A;  1XWT A;  1NI1 B;  2JG0 A;  1IA6 A;  4ZH1 A;  1TN8 B;  1O79 A;  3WIW A;  2IEJ B;  3E6U A;  3KSL B;  1TN6 B;  1LF9 A;  2EAB A;  1WZZ A;  1FAE A;  3KQ4 A;  4EL8 A;  3DSU B;  1O6Q A;  3M75 A;  3D3I A;  4WVB A;  2GZ6 A;  3M78 A;  1NXC A;  5KKB A;  3PZ3 B;  1TNU B;  1TNY B;  1N4P B;  4LNV A;  1H3B A;  1TN7 B;  2DRO A;  1VD5 A;  3M7E A;  4KTP A;  3SDU A;  5M7I A;  4LIX A;  1KKT A;  3AFJ A;  3WIQ A;  3QSP A;  1V5C A;  2JF4 A;  2V8I A;  2YIK A;  2I07 B;  2DRS A;  4XUV A;  3QXF A;  3QT9 A;  3SDQ A;  1L1Y A;  1H3C A;  2EAD A;  1F9O A;  2R2L B;  4ZH5 A;  3P2C A;  1NC5 A;  5FOB B;  3W7S A;  3HXE B;  3SFY B;  3Q79 B;  4DOD A;  1H54 A;  3DRA B;  1HCU A;  1LD7 B;  2AHG A;  2EAC A;  4LNG B;  3RX7 A;  2B39 A;  3ANJ A;  1H14 A;  3H2W A;  3WUX A;  1D8D B;  3E30 B;  2G02 A;  4FXK B;  4TF4 A;  1TF4 A;  5JPM B;  2F0Y B;  1JS4 A;  1GXO A;  1LF6 A;  3OED A;  3VW5 A;  4FUS A;  3SQC A;  3DSW B;  3RSY A;  5CA3 A;  1FCE A;  1CEM A;  3PYB A;  4GTR B;  1GSZ A;  5DGQ A;  1UG9 A;  4Z4L A;  4L6X A;  3WKI A;  1TNB B;  2Z07 A;  3GZK A;  1G6I A;  3CIH A;  2VN7 A;  4D4D A;  1H39 A;  4Q88 A;  2WIN B;  1TNO B;  4GTV B;  3TF4 A;  1GXM A;  4ZRP A;  3HXB B;  3DPY B;  4BOK A;  1K72 A;  4YCR A;  3W5N A;  2WYN A;  2V3P A;  1SA4 B;  4D4B A;  1KRF A;  5MEH A;  3RJ3 A;  2H6H B;  1NL4 B;  1WU5 A;  3ANI A;  3M7B A;  4L0G A;  3W7X A;  1UMP A;  2F6D A;  2WY7 A;  3Q7A B;  2H6G B;  5DGR A;  1N94 B;  3DSS B;  3GLY A;  3REN A;  1W6K A;  3W7U A;  4AYP A;  3M76 A;  4GTQ B;  1UT9 A;  1FPP B;  4CE7 A;  3QFZ A;  3S4C A;  1FO3 A;  3PYA A;  4L9P B;  1KWF A;  1N4S B;  4D4A A;  4TXT A;  3T33 A;  2BB6 A;  3QRY A;  3M7L A;  1GAI A;  2G0D A;  4GL3 A;  1WU6 A;  4ZG8 A;  1XW2 A;  1GAH A;  2FUZ A;  4V1S A;  2GOX A;  3EZ8 A;  5FO8 B;  1JCQ B;  4CJ0 A;  4MU9 A;  2VN4 A;  3E32 B;  3HXF B;  3SDR A;  2FBA A;  3DSX B;  3CU7 A;  2H6F B;  2V3N A;  3Q73 B;  2CQS A;  1L2A A;  2FV0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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