1S63B

Human protein farnesyltransferase complexed with l-778,123 and fpp
Total Genus 150
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
410
structure length
410
Chain Sequence
SSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVPGFE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Protein farnesyltransferase/geranylgeranyltransferase type I
publication title Crystallographic Analysis Reveals that Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I by Different Binding Modes.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 150
structure length 410
sequence length 410
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2004-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1s63B00
1N9AB 3Q79B 4GTQB 2V3PA 3Q7AB 1N4SB 1TNOB 2F0YB 5FO7B 1GXNA 1TNZB 2A73B 3KLSA 4FXKB 1H37A 2WY7A 2G0DA 4LNBB 1NL4B 1O6QA 1QBQB 1MZCB 1SQCA 4ZRPA 3D5RA 4V1RA 3DSUB 3Q7FB 1LTXB 3D5SA 4GTSB 1S63B 4D4AA 2BBCA 2H6GB 4M76A 1X81B 3DSTB 1HZFA 2H6HB 3OXUA 4D4DA 3OEDA 3HXBB 3SQCA 4D4BA 3C72B 4EHMB 5FOBB 3DSSB 1O6HA 1N4QB 3E30B 2H6FB 3G6JB 2BB6A 1O6RA 3SFXB 1O5MB 4GTOB 1JCRB 4ZH1A 1GXOA 1SA4B 1QQFA 1NI1B 2SQCA 1H3CA 2R2LB 1JCSB 3Q73B 1O1SB 4MU9A 2PMVA 3E34B 4D94A 4GTVB 1QSJA 1C3DA 4L9PB 4YDOB 4LNVA 3EU5B 4ZRQA 4GTRB 4GTMB 1GHQA 1TN6B 3EUVB 3HXEB 1N4RB 3PZ3B 3Q75B 1W6JA 1GSZA 2XQWA 3PZ4B 3Q78B 4MBGB 4V1SA 2ZISB 1FT1B 3KSQB 1TN7B 1H3AA 1SA5B 1UMPA 2GOXA 3PZ2B 1H35A 2PN5A 1FT2B 4FXGB 2WY8A 3HXFB 2BEDB 1H36A 3HXCB 1O1TB 2NOJA 2XWJB 1D8EB 3E33B 1JCQB 3DPYB 4GTTB 2XWBB 1H39A 4KKIA 1LD8B 2V8KA 4D4CA 2IEJB 4C1SA 5FO8B 4KKJA 3E37B 4ONTA 3HXDB 1R76A 1DCEB 1TNBB 2V3NA 3SFYB 3RJ3A 2B39A 4BOKA 5FO9B 1TN8B 2H6IB 1LD7B 3DSWB 1N4PB 1N94B 3KSLB 4LNGB 3K7XA 1D8DB 4GTPB 1KZPB 3DSVB 2G02A 2V8JA 1N95B 5JPNB 1S64B 5JPMB 1FPPB 1KZOB 3KQ4A 1TNUB 2BB5A 2WINB 3DRAB 2I07B 1O1RB 1W6KA 3DSXB 3E32B 1O79A 3CU7A 2V8IA 5AGDA 1GXMA 1H3BA 1TNYB 2WIIB 2ZIRB 3PZ1B 4YDEB 4BOJA
chains in the Genus database with same CATH superfamily
1N9AB 4GTQB 2FUQA 3Q7AB 1CB8A 2BRVX 4OK4A 2F0YB 3M7BA 5C05A 3KLSA 4FXKB 2WY7A 2FUTA 2WYNA 3QPFA 2YIKA 4LNBB 2JG0A 1KS8A 2E22A 4ZRPA 4ZG8A 3DSUB 3Q7FB 1LTXB 2EAEA 3D5SA 4GTSB 1G9GA 1S63B 4D4AA 3WIWA 5DHKA 2QNOA 3NFVA 1G87A 3DSTB 3EU8A 3HXBB 3SQCA 3C72B 4EHMB 1XW2A 4Z4LA 4OJZA 5E2JA 2ZZRA 3SAEA 2BB6A 3S4BA 1N7RA 1F9GA 1V7VA 3VW5A 1SA4B 2GH4A 1H3CA 2R2LB 2SQCA 3QT9A 5GY3A 1NXCA 1QSJA 3M00A 4L9PB 4ZH5A 2WDAA 3EU5B 2RGKA 4GTRB 1HXGA 5GW7A 3AFLA 1TN6B 1X9DA 1N4RB 1OJOA 1W6JA 1GSZA 4V1SA 4MBGB 1IA7A 2ZISB 2BRWA 3WKHA 1UMPA 1H35A 2PN5A 1FT2B 2DRQA 2JF4A 4FXGB 1HX9A 5GZKA 1I8QA 3W7XA 5EAUA 3HXCB 3E6UA 3RX8A 3ACSA 2B4FA 3E33B 3RSYA 3DPYB 4GTTB 3G4DA 4KKIA 1LD8B 1IS9A 1FMIA 2IEJB 1KKTA 4ONTA 5DHIA 1X1IA 1KWFA 3RJ3A 2B39A 4FUSA 3X17A 1TN8B 4CJ1A 1G6IA 3ACTA 1N94B 2BRPA 3K7XA 1D8DB 3M73A 4GTPB 2FBAA 5DGRA 1FAEA 4WVBA 5JPNB 1S64B 5JPMB 3KQ4A 3M02A 1WU4A 1IA6A 3QT3A 3M77A 2EACA 3DSXB 3CU7A 3EZ8A 1H3BA 2WIIB 2ZIRB 3WKFA 5IK0A 1WZZA 4KTPA 5KKBA 4E1YA 2V3PA 3M01A 5FO7B 1GXNA 5IKAA 1WU6A 2A73B 5M7YA 2VN4A 1GA2A 5CD2A 1KSDA 3WC3A 4F10A 1O6QA 1MZCB 3D5RA 1GAIA 2FV0A 1V5DA 1UG9A 1CEMA 3WKIA 3SDVA 1W3YA 3RENA 1L2AA 1X81B 1HZFA 4Q2BA 1AGMA 4L0GA 5IM1A 5FOBB 1J0MA 2ZBLA 1QAZA 2H6FB 3G6JB 1DL2A 3SFXB 1O5MB 4GTOB 4YCRA 2AFAA 1NI1B 1RQ5A 2D8LA 3GT5A 1RWAA 4D94A 1FCEA 1N20A 4ZRQA 2DRSA 4WVAA 1N7PA 1N24A 3EUVB 3SFYB 3PZ3B 1HN0A 1H12A 1FT1B 3KSQB 1GLMA 1SA5B 2GOXA 3PZ2B 5CA3A 3E7JA 2WY8A 3HXFB 3PMMA 4NEIA 1O1TB 3GZKA 1H39A 1HXAA 4D4CA 4LIXA 1LOHA 3M72A 4GAXA 3QSPA 2DRRA 3QFZA 3ANIA 3HXDB 1R76A 1RWGA 4AYQA 4BOKA 1LD7B 1N4PB 4LNGB 3D3IA 3M74A 2AHGA 5DGQA 5IK9A 3H3KA 3N0GA 1FO3A 3W7TA 3WIQA 1RWCA 1DOGA 2EABA 2I07B 1O1RB 2RI9A 1W6KA 3E32B 1EGUA 4YDEB 2FUZA 3WUXA 2X03A 3SDUA 3ANKA 4MMHA 4DI5A 3Q79B 1GAHA 4J5TA 1N4SB 3EQAA 3RRSA 3QXQA 3W7WA 1TNZB 5ILYA 1OJMA 1F1SA 5ILKA 1OJPA 3PYBA 1QBQB 3ON6A 3TF4A 1SQCA 1XWQA 4FNVA 1KRFA 4Z4JA 1OJNA 2EADA 2FV1A 2BBCA 3S4CA 4M76A 3AFJA 3E73A 5JMFA 1V7WA 3S4DA 3OXUA 2H6HB 3OEDA 4D4BA 5IL8A 1X1JA 1O6HA 3W7UA 1LF9A 2DROA 1FP3A 2ONGA 3E30B 1O6RA 4ZH1A 1N7QA 1JCRB 1RW9A 1N22A 1GXOA 1HM2A 1JCSB 3Q73B 1O1SB 1C82A 1ULVA 3W5MA 2Z07A 1C3DA 3SDQA 1N23A 4YDOB 4LNVA 3A3VA 3M7EA 4FJQA 1GHQA 3QG0A 4TF4A 1HMUA 3SDRA 2XQWA 3PZ4B 3G4FA 5M7IA 3VSMA 4GL3A 3QDEA 3VSNA 1H14A 2J5CA 3P5RA 1VD5A 2NOJA 2Q1FA 2XWJB 4KTRA 1JCQB 2XWBB 5CZLA 4TXTA 3M76A 1K72A 3GLYA 3QFYA 2E24A 1AYXA 3E37B 3S9VA 1TNBB 4WU0A 4QT9A 1NC5A 5FO9B 2H6IB 4L6XA 3H2WA 3DSWB 4OZWA 2RI8A 3S4AA 2OKXA 2AHFA 3W5NA 1N21A 3K11A 3DSVB 2G02A 5IK6A 1FPPB 1KZOB 2XFGA 3A0OA 1TNUB 1LF6A 2WINB 3DRAB 1V7XA 1O79A 5AGDA 1N1ZA 2V8IA 3PZ1B 4BOJA 2GZ6A 1HV6A 1HXCA 3H7LA 3CIHA 4RNQA 1TNOB 3VXDA 2A8ZA 4MMIA 3WKGA 5IL3A 1H37A 2G0DA 3P5PA 1NL4B 1TF4A 2JJBA 5ILDA 3M7CA 1J0NA 2H6GB 3RX5A 4AYPA 4AYRA 4D4DA 5ILJA 1V5CA 3DSSB 1L1YA 1N4QB 3LZ9A 1F9OA 1N1BA 5JMDA 1FBWA 1F9DA 3T33A 4F13A 1QQFA 4OZVA 3NNBA 1LXKA 3RX7A 4MU9A 4CE7A 2PMVA 1N7NA 3E34B 4GTVB 4EL8A 1HM3A 1G9JA 5ILIA 4GTMB 3HXEB 1X1HA 2CQSA 4V1RA 4XUVA 3Q75B 2D5JA 3Q78B 1KFGA 2WCOA 1TN7B 4JJJA 1H3AA 4WVCA 1CLCA 1LXMA 2VN7A 2BEDB 1H36A 1XWTA 5EATA 3QXFA 1D8EB 3M71A 3M75A 4DODA 5IKHA 1KSCA 2V8KA 1H54A 4DOEA 4OK2A 4C1SA 1HCUA 5FO8B 4KKJA 3E80A 4CJ0A 1WU5A 2V3NA 1DCEB 2CQTA 3P2CA 3QWTA 3M78A 3PYAA 3KSLB 3W7SA 3QRYA 3ANJA 4Q88A 1N7OA 3WIRA 1KZPB 1UT9A 3M7LA 4AYOA 1H13A 2V8JA 1FBOA 5EASA 1N95B 5ILHA 1RWHA 5ILZA 1RWFA 3N0FA 2BB5A 2F6DA 2ONHA 1HMWA 1FO2A 1KREA 1JS4A 2NVPA 1GXMA 5MEHA 1TNYB 2P0VA 3SDTA
chains in the Genus database with same CATH topology
1N9AB 4GTQB 3Q7AB 2F0YB 3M7BA 3KLSA 4FXKB 2WY7A 2WYNA 3QPFA 2YIKA 4LNBB 2JG0A 1KS8A 4ZRPA 4ZG8A 3DSUB 3Q7FB 1LTXB 2EAEA 3D5SA 4GTSB 1G9GA 1S63B 4D4AA 3WIWA 2QNOA 1G87A 3DSTB 3EU8A 3HXBB 3SQCA 3C72B 4EHMB 1XW2A 4Z4LA 5E2JA 2ZZRA 3SAEA 2BB6A 3S4BA 1V7VA 3VW5A 1SA4B 2GH4A 1H3CA 2R2LB 2SQCA 3QT9A 5GY3A 1NXCA 1QSJA 4L9PB 4ZH5A 3EU5B 2RGKA 4GTRB 5GW7A 1TN6B 1X9DA 1N4RB 1W6JA 1GSZA 4V1SA 4MBGB 1IA7A 2ZISB 3WKHA 1UMPA 1H35A 2PN5A 1FT2B 2DRQA 2JF4A 4FXGB 5GZKA 3W7XA 3HXCB 3E6UA 3RX8A 3ACSA 2B4FA 3E33B 3RSYA 3DPYB 4GTTB 4KKIA 1LD8B 1IS9A 1FMIA 2IEJB 1KKTA 4ONTA 1KWFA 3RJ3A 2B39A 4FUSA 3X17A 1TN8B 4CJ1A 1G6IA 3ACTA 1N94B 3K7XA 1D8DB 3M73A 4GTPB 2FBAA 5DGRA 1FAEA 4WVBA 5JPNB 1S64B 5JPMB 3KQ4A 1WU4A 1IA6A 3QT3A 3M77A 2EACA 3DSXB 3CU7A 3EZ8A 1H3BA 2WIIB 2ZIRB 3WKFA 1WZZA 4KTPA 5KKBA 2V3PA 5FO7B 1GXNA 1WU6A 2A73B 5M7YA 2VN4A 1GA2A 5CD2A 1KSDA 3WC3A 1O6QA 1MZCB 3D5RA 1GAIA 2FV0A 1V5DA 1UG9A 1CEMA 3WKIA 3SDVA 3RENA 1L2AA 1X81B 1HZFA 4Q2BA 1AGMA 4L0GA 5FOBB 2ZBLA 2H6FB 3G6JB 1DL2A 3SFXB 1O5MB 4GTOB 4YCRA 2AFAA 1NI1B 1RQ5A 2D8LA 3GT5A 4D94A 1FCEA 4ZRQA 2DRSA 4WVAA 3EUVB 3SFYB 3PZ3B 1H12A 1FT1B 3KSQB 1GLMA 1SA5B 2GOXA 3PZ2B 5CA3A 2WY8A 3HXFB 3PMMA 1O1TB 3GZKA 1H39A 4D4CA 4LIXA 3M72A 3QSPA 2DRRA 3QFZA 3ANIA 3HXDB 1R76A 4AYQA 4BOKA 1LD7B 1N4PB 4LNGB 3D3IA 3M74A 2AHGA 5DGQA 3H3KA 1FO3A 3W7TA 3WIQA 1DOGA 2EABA 2I07B 1O1RB 2RI9A 1W6KA 3E32B 4YDEB 2FUZA 3WUXA 3SDUA 3ANKA 3Q79B 1GAHA 4J5TA 1N4SB 3EQAA 3RRSA 3QXQA 3W7WA 1TNZB 3PYBA 1QBQB 3ON6A 3TF4A 1SQCA 1XWQA 1KRFA 4Z4JA 2FV1A 2EADA 2BBCA 3S4CA 4M76A 3AFJA 3E73A 1V7WA 3S4DA 3OXUA 2H6HB 3OEDA 4D4BA 3W7UA 1O6HA 1LF9A 2DROA 1FP3A 3E30B 1O6RA 4ZH1A 1JCRB 1GXOA 1JCSB 3Q73B 1O1SB 1ULVA 3W5MA 2Z07A 1C3DA 3SDQA 4YDOB 4LNVA 3A3VA 3M7EA 1GHQA 3QG0A 4TF4A 3SDRA 2XQWA 3PZ4B 5M7IA 4GL3A 3QDEA 1H14A 3P5RA 1VD5A 2NOJA 2XWJB 4KTRA 1JCQB 2XWBB 5CZLA 4TXTA 3M76A 1K72A 3GLYA 3QFYA 1AYXA 3E37B 3S9VA 1TNBB 4WU0A 4QT9A 1NC5A 5FO9B 2H6IB 4L6XA 3H2WA 3DSWB 2RI8A 3S4AA 2OKXA 2AHFA 3W5NA 3K11A 3DSVB 2G02A 1FPPB 1KZOB 2XFGA 1TNUB 1LF6A 2WINB 3DRAB 1V7XA 1O79A 5AGDA 2V8IA 3PZ1B 4BOJA 2GZ6A 3H7LA 3CIHA 1TNOB 3VXDA 2A8ZA 3WKGA 1H37A 2G0DA 3P5PA 1NL4B 1TF4A 2JJBA 3M7CA 2H6GB 3RX5A 4AYPA 4AYRA 4D4DA 1V5CA 3DSSB 1L1YA 1N4QB 1F9OA 1FBWA 1F9DA 3T33A 1QQFA 3RX7A 4MU9A 4CE7A 2PMVA 3E34B 4GTVB 4EL8A 1G9JA 4GTMB 3HXEB 2CQSA 4V1RA 4XUVA 3Q75B 2D5JA 3Q78B 1KFGA 1TN7B 4JJJA 1H3AA 4WVCA 1CLCA 2VN7A 2BEDB 1H36A 1XWTA 3QXFA 1D8EB 3M71A 3M75A 4DODA 1KSCA 2V8KA 1H54A 4DOEA 4C1SA 1HCUA 5FO8B 4KKJA 4CJ0A 1WU5A 2V3NA 1DCEB 2CQTA 3P2CA 3QWTA 3PYAA 3M78A 3KSLB 3W7SA 3QRYA 3ANJA 4Q88A 3WIRA 1KZPB 1UT9A 3M7LA 4AYOA 1H13A 2V8JA 1FBOA 1N95B 2BB5A 2F6DA 1FO2A 1KREA 1JS4A 2NVPA 1GXMA 5MEHA 1TNYB 2P0VA 3SDTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N9A B;  3Q79 B;  4GTQ B;  2V3P A;  3Q7A B;  1N4S B;  1TNO B;  2F0Y B;  5FO7 B;  1GXN A;  1TNZ B;  2A73 B;  3KLS A;  4FXK B;  1H37 A;  2WY7 A;  2G0D A;  4LNB B;  1NL4 B;  1O6Q A;  1QBQ B;  1MZC B;  1SQC A;  4ZRP A;  3D5R A;  4V1R A;  3DSU B;  3Q7F B;  1LTX B;  3D5S A;  4GTS B;  1S63 B;  4D4A A;  2BBC A;  2H6G B;  4M76 A;  1X81 B;  3DST B;  1HZF A;  2H6H B;  3OXU A;  4D4D A;  3OED A;  3HXB B;  3SQC A;  4D4B A;  3C72 B;  4EHM B;  5FOB B;  3DSS B;  1O6H A;  1N4Q B;  3E30 B;  2H6F B;  3G6J B;  2BB6 A;  1O6R A;  3SFX B;  1O5M B;  4GTO B;  1JCR B;  4ZH1 A;  1GXO A;  1SA4 B;  1QQF A;  1NI1 B;  2SQC A;  1H3C A;  2R2L B;  1JCS B;  3Q73 B;  1O1S B;  4MU9 A;  2PMV A;  3E34 B;  4D94 A;  4GTV B;  1QSJ A;  1C3D A;  4L9P B;  4YDO B;  4LNV A;  3EU5 B;  4ZRQ A;  4GTR B;  4GTM B;  1GHQ A;  1TN6 B;  3EUV B;  3HXE B;  1N4R B;  3PZ3 B;  3Q75 B;  1W6J A;  1GSZ A;  2XQW A;  3PZ4 B;  3Q78 B;  4MBG B;  4V1S A;  2ZIS B;  1FT1 B;  3KSQ B;  1TN7 B;  1H3A A;  1SA5 B;  1UMP A;  2GOX A;  3PZ2 B;  1H35 A;  2PN5 A;  1FT2 B;  4FXG B;  2WY8 A;  3HXF B;  2BED B;  1H36 A;  3HXC B;  1O1T B;  2NOJ A;  2XWJ B;  1D8E B;  3E33 B;  1JCQ B;  3DPY B;  4GTT B;  2XWB B;  1H39 A;  4KKI A;  1LD8 B;  2V8K A;  4D4C A;  2IEJ B;  4C1S A;  5FO8 B;  4KKJ A;  3E37 B;  4ONT A;  3HXD B;  1R76 A;  1DCE B;  1TNB B;  2V3N A;  3SFY B;  3RJ3 A;  2B39 A;  4BOK A;  5FO9 B;  1TN8 B;  2H6I B;  1LD7 B;  3DSW B;  1N4P B;  1N94 B;  3KSL B;  4LNG B;  3K7X A;  1D8D B;  4GTP B;  1KZP B;  3DSV B;  2G02 A;  2V8J A;  1N95 B;  5JPN B;  1S64 B;  5JPM B;  1FPP B;  1KZO B;  3KQ4 A;  1TNU B;  2BB5 A;  2WIN B;  3DRA B;  2I07 B;  1O1R B;  1W6K A;  3DSX B;  3E32 B;  1O79 A;  3CU7 A;  2V8I A;  5AGD A;  1GXM A;  1H3B A;  1TNY B;  2WII B;  2ZIR B;  3PZ1 B;  4YDE B;  4BOJ A; 
#chains in the Genus database with same CATH topology
 1N9A B;  4GTQ B;  2FUQ A;  3Q7A B;  1CB8 A;  2BRV X;  4OK4 A;  2F0Y B;  3M7B A;  5C05 A;  3KLS A;  4FXK B;  2WY7 A;  2FUT A;  2WYN A;  3QPF A;  2YIK A;  4LNB B;  2JG0 A;  1KS8 A;  2E22 A;  4ZRP A;  4ZG8 A;  3DSU B;  3Q7F B;  1LTX B;  2EAE A;  3D5S A;  4GTS B;  1G9G A;  1S63 B;  4D4A A;  3WIW A;  5DHK A;  2QNO A;  3NFV A;  1G87 A;  3DST B;  3EU8 A;  3HXB B;  3SQC A;  3C72 B;  4EHM B;  1XW2 A;  4Z4L A;  4OJZ A;  5E2J A;  2ZZR A;  3SAE A;  2BB6 A;  3S4B A;  1N7R A;  1F9G A;  1V7V A;  3VW5 A;  1SA4 B;  2GH4 A;  1H3C A;  2R2L B;  2SQC A;  3QT9 A;  5GY3 A;  1NXC A;  1QSJ A;  3M00 A;  4L9P B;  4ZH5 A;  2WDA A;  3EU5 B;  2RGK A;  4GTR B;  1HXG A;  5GW7 A;  3AFL A;  1TN6 B;  1X9D A;  1N4R B;  1OJO A;  1W6J A;  1GSZ A;  4V1S A;  4MBG B;  1IA7 A;  2ZIS B;  2BRW A;  3WKH A;  1UMP A;  1H35 A;  2PN5 A;  1FT2 B;  2DRQ A;  2JF4 A;  4FXG B;  1HX9 A;  5GZK A;  1I8Q A;  3W7X A;  5EAU A;  3HXC B;  3E6U A;  3RX8 A;  3ACS A;  2B4F A;  3E33 B;  3RSY A;  3DPY B;  4GTT B;  3G4D A;  4KKI A;  1LD8 B;  1IS9 A;  1FMI A;  2IEJ B;  1KKT A;  4ONT A;  5DHI A;  1X1I A;  1KWF A;  3RJ3 A;  2B39 A;  4FUS A;  3X17 A;  1TN8 B;  4CJ1 A;  1G6I A;  3ACT A;  1N94 B;  2BRP A;  3K7X A;  1D8D B;  3M73 A;  4GTP B;  2FBA A;  5DGR A;  1FAE A;  4WVB A;  5JPN B;  1S64 B;  5JPM B;  3KQ4 A;  3M02 A;  1WU4 A;  1IA6 A;  3QT3 A;  3M77 A;  2EAC A;  3DSX B;  3CU7 A;  3EZ8 A;  1H3B A;  2WII B;  2ZIR B;  3WKF A;  5IK0 A;  1WZZ A;  4KTP A;  5KKB A;  4E1Y A;  2V3P A;  3M01 A;  5FO7 B;  1GXN A;  5IKA A;  1WU6 A;  2A73 B;  5M7Y A;  2VN4 A;  1GA2 A;  5CD2 A;  1KSD A;  3WC3 A;  4F10 A;  1O6Q A;  1MZC B;  3D5R A;  1GAI A;  2FV0 A;  1V5D A;  1UG9 A;  1CEM A;  3WKI A;  3SDV A;  1W3Y A;  3REN A;  1L2A A;  1X81 B;  1HZF A;  4Q2B A;  1AGM A;  4L0G A;  5IM1 A;  5FOB B;  1J0M A;  2ZBL A;  1QAZ A;  2H6F B;  3G6J B;  1DL2 A;  3SFX B;  1O5M B;  4GTO B;  4YCR A;  2AFA A;  1NI1 B;  1RQ5 A;  2D8L A;  3GT5 A;  1RWA A;  4D94 A;  1FCE A;  1N20 A;  4ZRQ A;  2DRS A;  4WVA A;  1N7P A;  1N24 A;  3EUV B;  3SFY B;  3PZ3 B;  1HN0 A;  1H12 A;  1FT1 B;  3KSQ B;  1GLM A;  1SA5 B;  2GOX A;  3PZ2 B;  5CA3 A;  3E7J A;  2WY8 A;  3HXF B;  3PMM A;  4NEI A;  1O1T B;  3GZK A;  1H39 A;  1HXA A;  4D4C A;  4LIX A;  1LOH A;  3M72 A;  4GAX A;  3QSP A;  2DRR A;  3QFZ A;  3ANI A;  3HXD B;  1R76 A;  1RWG A;  4AYQ A;  4BOK A;  1LD7 B;  1N4P B;  4LNG B;  3D3I A;  3M74 A;  2AHG A;  5DGQ A;  5IK9 A;  3H3K A;  3N0G A;  1FO3 A;  3W7T A;  3WIQ A;  1RWC A;  1DOG A;  2EAB A;  2I07 B;  1O1R B;  2RI9 A;  1W6K A;  3E32 B;  1EGU A;  4YDE B;  2FUZ A;  3WUX A;  2X03 A;  3SDU A;  3ANK A;  4MMH A;  4DI5 A;  3Q79 B;  1GAH A;  4J5T A;  1N4S B;  3EQA A;  3RRS A;  3QXQ A;  3W7W A;  1TNZ B;  5ILY A;  1OJM A;  1F1S A;  5ILK A;  1OJP A;  3PYB A;  1QBQ B;  3ON6 A;  3TF4 A;  1SQC A;  1XWQ A;  4FNV A;  1KRF A;  4Z4J A;  1OJN A;  2EAD A;  2FV1 A;  2BBC A;  3S4C A;  4M76 A;  3AFJ A;  3E73 A;  5JMF A;  1V7W A;  3S4D A;  3OXU A;  2H6H B;  3OED A;  4D4B A;  5IL8 A;  1X1J A;  1O6H A;  3W7U A;  1LF9 A;  2DRO A;  1FP3 A;  2ONG A;  3E30 B;  1O6R A;  4ZH1 A;  1N7Q A;  1JCR B;  1RW9 A;  1N22 A;  1GXO A;  1HM2 A;  1JCS B;  3Q73 B;  1O1S B;  1C82 A;  1ULV A;  3W5M A;  2Z07 A;  1C3D A;  3SDQ A;  1N23 A;  4YDO B;  4LNV A;  3A3V A;  3M7E A;  4FJQ A;  1GHQ A;  3QG0 A;  4TF4 A;  1HMU A;  3SDR A;  2XQW A;  3PZ4 B;  3G4F A;  5M7I A;  3VSM A;  4GL3 A;  3QDE A;  3VSN A;  1H14 A;  2J5C A;  3P5R A;  1VD5 A;  2NOJ A;  2Q1F A;  2XWJ B;  4KTR A;  1JCQ B;  2XWB B;  5CZL A;  4TXT A;  3M76 A;  1K72 A;  3GLY A;  3QFY A;  2E24 A;  1AYX A;  3E37 B;  3S9V A;  1TNB B;  4WU0 A;  4QT9 A;  1NC5 A;  5FO9 B;  2H6I B;  4L6X A;  3H2W A;  3DSW B;  4OZW A;  2RI8 A;  3S4A A;  2OKX A;  2AHF A;  3W5N A;  1N21 A;  3K11 A;  3DSV B;  2G02 A;  5IK6 A;  1FPP B;  1KZO B;  2XFG A;  3A0O A;  1TNU B;  1LF6 A;  2WIN B;  3DRA B;  1V7X A;  1O79 A;  5AGD A;  1N1Z A;  2V8I A;  3PZ1 B;  4BOJ A;  2GZ6 A;  1HV6 A;  1HXC A;  3H7L A;  3CIH A;  4RNQ A;  1TNO B;  3VXD A;  2A8Z A;  4MMI A;  3WKG A;  5IL3 A;  1H37 A;  2G0D A;  3P5P A;  1NL4 B;  1TF4 A;  2JJB A;  5ILD A;  3M7C A;  1J0N A;  2H6G B;  3RX5 A;  4AYP A;  4AYR A;  4D4D A;  5ILJ A;  1V5C A;  3DSS B;  1L1Y A;  1N4Q B;  3LZ9 A;  1F9O A;  1N1B A;  5JMD A;  1FBW A;  1F9D A;  3T33 A;  4F13 A;  1QQF A;  4OZV A;  3NNB A;  1LXK A;  3RX7 A;  4MU9 A;  4CE7 A;  2PMV A;  1N7N A;  3E34 B;  4GTV B;  4EL8 A;  1HM3 A;  1G9J A;  5ILI A;  4GTM B;  3HXE B;  1X1H A;  2CQS A;  4V1R A;  4XUV A;  3Q75 B;  2D5J A;  3Q78 B;  1KFG A;  2WCO A;  1TN7 B;  4JJJ A;  1H3A A;  4WVC A;  1CLC A;  1LXM A;  2VN7 A;  2BED B;  1H36 A;  1XWT A;  5EAT A;  3QXF A;  1D8E B;  3M71 A;  3M75 A;  4DOD A;  5IKH A;  1KSC A;  2V8K A;  1H54 A;  4DOE A;  4OK2 A;  4C1S A;  1HCU A;  5FO8 B;  4KKJ A;  3E80 A;  4CJ0 A;  1WU5 A;  2V3N A;  1DCE B;  2CQT A;  3P2C A;  3QWT A;  3M78 A;  3PYA A;  3KSL B;  3W7S A;  3QRY A;  3ANJ A;  4Q88 A;  1N7O A;  3WIR A;  1KZP B;  1UT9 A;  3M7L A;  4AYO A;  1H13 A;  2V8J A;  1FBO A;  5EAS A;  1N95 B;  5ILH A;  1RWH A;  5ILZ A;  1RWF A;  3N0F A;  2BB5 A;  2F6D A;  2ONH A;  1HMW A;  1FO2 A;  1KRE A;  1JS4 A;  2NVP A;  1GXM A;  5MEH A;  1TNY B;  2P0V A;  3SDT A; 
#chains in the Genus database with same CATH homology
 1N9A B;  4GTQ B;  3Q7A B;  2F0Y B;  3M7B A;  3KLS A;  4FXK B;  2WY7 A;  2WYN A;  3QPF A;  2YIK A;  4LNB B;  2JG0 A;  1KS8 A;  4ZRP A;  4ZG8 A;  3DSU B;  3Q7F B;  1LTX B;  2EAE A;  3D5S A;  4GTS B;  1G9G A;  1S63 B;  4D4A A;  3WIW A;  2QNO A;  1G87 A;  3DST B;  3EU8 A;  3HXB B;  3SQC A;  3C72 B;  4EHM B;  1XW2 A;  4Z4L A;  5E2J A;  2ZZR A;  3SAE A;  2BB6 A;  3S4B A;  1V7V A;  3VW5 A;  1SA4 B;  2GH4 A;  1H3C A;  2R2L B;  2SQC A;  3QT9 A;  5GY3 A;  1NXC A;  1QSJ A;  4L9P B;  4ZH5 A;  3EU5 B;  2RGK A;  4GTR B;  5GW7 A;  1TN6 B;  1X9D A;  1N4R B;  1W6J A;  1GSZ A;  4V1S A;  4MBG B;  1IA7 A;  2ZIS B;  3WKH A;  1UMP A;  1H35 A;  2PN5 A;  1FT2 B;  2DRQ A;  2JF4 A;  4FXG B;  5GZK A;  3W7X A;  3HXC B;  3E6U A;  3RX8 A;  3ACS A;  2B4F A;  3E33 B;  3RSY A;  3DPY B;  4GTT B;  4KKI A;  1LD8 B;  1IS9 A;  1FMI A;  2IEJ B;  1KKT A;  4ONT A;  1KWF A;  3RJ3 A;  2B39 A;  4FUS A;  3X17 A;  1TN8 B;  4CJ1 A;  1G6I A;  3ACT A;  1N94 B;  3K7X A;  1D8D B;  3M73 A;  4GTP B;  2FBA A;  5DGR A;  1FAE A;  4WVB A;  5JPN B;  1S64 B;  5JPM B;  3KQ4 A;  1WU4 A;  1IA6 A;  3QT3 A;  3M77 A;  2EAC A;  3DSX B;  3CU7 A;  3EZ8 A;  1H3B A;  2WII B;  2ZIR B;  3WKF A;  1WZZ A;  4KTP A;  5KKB A;  2V3P A;  5FO7 B;  1GXN A;  1WU6 A;  2A73 B;  5M7Y A;  2VN4 A;  1GA2 A;  5CD2 A;  1KSD A;  3WC3 A;  1O6Q A;  1MZC B;  3D5R A;  1GAI A;  2FV0 A;  1V5D A;  1UG9 A;  1CEM A;  3WKI A;  3SDV A;  3REN A;  1L2A A;  1X81 B;  1HZF A;  4Q2B A;  1AGM A;  4L0G A;  5FOB B;  2ZBL A;  2H6F B;  3G6J B;  1DL2 A;  3SFX B;  1O5M B;  4GTO B;  4YCR A;  2AFA A;  1NI1 B;  1RQ5 A;  2D8L A;  3GT5 A;  4D94 A;  1FCE A;  4ZRQ A;  2DRS A;  4WVA A;  3EUV B;  3SFY B;  3PZ3 B;  1H12 A;  1FT1 B;  3KSQ B;  1GLM A;  1SA5 B;  2GOX A;  3PZ2 B;  5CA3 A;  2WY8 A;  3HXF B;  3PMM A;  1O1T B;  3GZK A;  1H39 A;  4D4C A;  4LIX A;  3M72 A;  3QSP A;  2DRR A;  3QFZ A;  3ANI A;  3HXD B;  1R76 A;  4AYQ A;  4BOK A;  1LD7 B;  1N4P B;  4LNG B;  3D3I A;  3M74 A;  2AHG A;  5DGQ A;  3H3K A;  1FO3 A;  3W7T A;  3WIQ A;  1DOG A;  2EAB A;  2I07 B;  1O1R B;  2RI9 A;  1W6K A;  3E32 B;  4YDE B;  2FUZ A;  3WUX A;  3SDU A;  3ANK A;  3Q79 B;  1GAH A;  4J5T A;  1N4S B;  3EQA A;  3RRS A;  3QXQ A;  3W7W A;  1TNZ B;  3PYB A;  1QBQ B;  3ON6 A;  3TF4 A;  1SQC A;  1XWQ A;  1KRF A;  4Z4J A;  2FV1 A;  2EAD A;  2BBC A;  3S4C A;  4M76 A;  3AFJ A;  3E73 A;  1V7W A;  3S4D A;  3OXU A;  2H6H B;  3OED A;  4D4B A;  3W7U A;  1O6H A;  1LF9 A;  2DRO A;  1FP3 A;  3E30 B;  1O6R A;  4ZH1 A;  1JCR B;  1GXO A;  1JCS B;  3Q73 B;  1O1S B;  1ULV A;  3W5M A;  2Z07 A;  1C3D A;  3SDQ A;  4YDO B;  4LNV A;  3A3V A;  3M7E A;  1GHQ A;  3QG0 A;  4TF4 A;  3SDR A;  2XQW A;  3PZ4 B;  5M7I A;  4GL3 A;  3QDE A;  1H14 A;  3P5R A;  1VD5 A;  2NOJ A;  2XWJ B;  4KTR A;  1JCQ B;  2XWB B;  5CZL A;  4TXT A;  3M76 A;  1K72 A;  3GLY A;  3QFY A;  1AYX A;  3E37 B;  3S9V A;  1TNB B;  4WU0 A;  4QT9 A;  1NC5 A;  5FO9 B;  2H6I B;  4L6X A;  3H2W A;  3DSW B;  2RI8 A;  3S4A A;  2OKX A;  2AHF A;  3W5N A;  3K11 A;  3DSV B;  2G02 A;  1FPP B;  1KZO B;  2XFG A;  1TNU B;  1LF6 A;  2WIN B;  3DRA B;  1V7X A;  1O79 A;  5AGD A;  2V8I A;  3PZ1 B;  4BOJ A;  2GZ6 A;  3H7L A;  3CIH A;  1TNO B;  3VXD A;  2A8Z A;  3WKG A;  1H37 A;  2G0D A;  3P5P A;  1NL4 B;  1TF4 A;  2JJB A;  3M7C A;  2H6G B;  3RX5 A;  4AYP A;  4AYR A;  4D4D A;  1V5C A;  3DSS B;  1L1Y A;  1N4Q B;  1F9O A;  1FBW A;  1F9D A;  3T33 A;  1QQF A;  3RX7 A;  4MU9 A;  4CE7 A;  2PMV A;  3E34 B;  4GTV B;  4EL8 A;  1G9J A;  4GTM B;  3HXE B;  2CQS A;  4V1R A;  4XUV A;  3Q75 B;  2D5J A;  3Q78 B;  1KFG A;  1TN7 B;  4JJJ A;  1H3A A;  4WVC A;  1CLC A;  2VN7 A;  2BED B;  1H36 A;  1XWT A;  3QXF A;  1D8E B;  3M71 A;  3M75 A;  4DOD A;  1KSC A;  2V8K A;  1H54 A;  4DOE A;  4C1S A;  1HCU A;  5FO8 B;  4KKJ A;  4CJ0 A;  1WU5 A;  2V3N A;  1DCE B;  2CQT A;  3P2C A;  3QWT A;  3PYA A;  3M78 A;  3KSL B;  3W7S A;  3QRY A;  3ANJ A;  4Q88 A;  3WIR A;  1KZP B;  1UT9 A;  3M7L A;  4AYO A;  1H13 A;  2V8J A;  1FBO A;  1N95 B;  2BB5 A;  2F6D A;  1FO2 A;  1KRE A;  1JS4 A;  2NVP A;  1GXM A;  5MEH A;  1TNY B;  2P0V A;  3SDT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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