1S63B

Human protein farnesyltransferase complexed with l-778,123 and fpp
Total Genus 150
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
410
structure length
410
Chain Sequence
SSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVPGFE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Protein farnesyltransferase/geranylgeranyltransferase type I
publication title Crystallographic Analysis Reveals that Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I by Different Binding Modes.
pubmed doi rcsb
source organism Homo sapiens
total genus 150
structure length 410
sequence length 410
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2004-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1s63B00
2G0DA 1C3DA 3KSQB 1FT2B 4LNGB 2BEDB 1MZCB 5AGDA 2ZISB 1H39A 1TNOB 1HZFA 1TNYB 2V3NA 4GTPB 4D4DA 3Q79B 3CU7A 2H6HB 1KZPB 1LTXB 3HXCB 3DPYB 3DSSB 1QQFA 4GTSB 2BB6A 2WIIB 4BOKA 2NOJA 1SA5B 4GTMB 4L9PB 3KQ4A 5FO7B 1LD8B 2PN5A 3D5SA 1GHQA 3SFXB 1O1SB 1UMPA 4KKIA 1QSJA 1TN6B 3K7XA 1NI1B 3HXEB 4YDOB 4GTRB 1N4QB 2XWJB 4D4AA 1S63B 1R76A 1H35A 3SFYB 3PZ2B 1O6QA 2WY8A 4ZH1A 1O6HA 2H6FB 2B39A 1O6RA 1W6JA 3DRAB 2H6IB 1O79A 4LNVA 3OEDA 3D5RA 3DSWB 3HXBB 3Q7AB 1GXNA 1W6KA 3HXFB 3DSVB 1H36A 3SQCA 3PZ1B 3PZ4B 3DSXB 2XWBB 1N4SB 4GTVB 4D94A 2V3PA 1TN8B 2SQCA 2XQWA 2G02A 1GXOA 3HXDB 3PZ3B 2V8KA 1DCEB 2PMVA 3EUVB 2BB5A 3DSTB 3C72B 1O1TB 4GTQB 4MU9A 1H3AA 4V1SA 1GXMA 3E30B 2R2LB 2F0YB 2WINB 1O5MB 1N4PB 4V1RA 2I07B 1D8DB 3E32B 2H6GB 1GSZA 1S64B 1SQCA 1TN7B 4GTOB 4ONTA 3Q7FB 3Q73B 1O1RB 4FXKB 1LD7B 4EHMB 1JCSB 2GOXA 4D4BA 1SA4B 1N95B 2V8IA 3KSLB 4ZRQA 4FXGB 5FOBB 5FO8B 1TNBB 3E37B 4M76A 1TNZB 1D8EB 1FPPB 3OXUA 1X81B 4YDEB 4D4CA 4GTTB 1JCQB 1FT1B 1H3BA 1TNUB 1QBQB 3E33B 4C1SA 3Q78B 5FO9B 3KLSA 2WY7A 3EU5B 4MBGB 2IEJB 2ZIRB 3G6JB 3E34B 3Q75B 1JCRB 4KKJA 3RJ3A 1NL4B 2BBCA 1H37A 4BOJA 2A73B 4LNBB 1N94B 2V8JA 1KZOB 4ZRPA 5JPMB 1H3CA 5JPNB 3DSUB 1N4RB 1N9AB
chains in the Genus database with same CATH superfamily
2G0DA 1FT2B 5CZLA 3W7WA 2GZ6A 1MZCB 3S4CA 1H39A 1HZFA 4D4DA 1XWTA 3QWTA 1JS4A 3CU7A 1RWHA 1AYXA 4WVAA 5GZKA 4MMHA 4GTSB 4GAXA 1G87A 1FAEA 3M01A 1LXKA 3D5SA 3SDRA 1J0NA 1UMPA 3K7XA 1KREA 1N23A 1N7RA 1W3YA 1RW9A 1FO2A 3A0OA 2AFAA 2YIKA 4Q88A 1KSCA 3WKFA 1O79A 4LNVA 3D5RA 2CQTA 1F9DA 1W6KA 1H36A 4TXTA 5IL8A 5MEHA 1N4SB 5JMFA 4EL8A 5KKBA 4D94A 1HX9A 5EASA 3M76A 2SQCA 1GXOA 1N1BA 2FUQA 3E7JA 3EUVB 4ZH5A 3DSTB 1TF4A 3C72B 2RGKA 4L6XA 3M02A 1H3AA 3E30B 3E73A 2VN4A 5IM1A 2I07B 2AHGA 4OZVA 3E32B 1N1ZA 3RX5A 1SQCA 1H14A 3A3VA 4ONTA 4FXKB 3G4DA 1JCSB 2GOXA 2BRPA 1FP3A 1SA4B 1V5CA 1N95B 3E6UA 5DHIA 3VXDA 4XUVA 2B4FA 3E37B 3P2CA 3S4BA 5ILZA 1X9DA 1X81B 2X03A 3AFJA 1FT1B 1TNUB 1C82A 5FO9B 2P0VA 3EQAA 4MBGB 1GLMA 2ZIRB 3G6JB 1H12A 4KKJA 3ON6A 5IK9A 2BBCA 4BOJA 2EAEA 2RI9A 3H2WA 5JPMB 3QSPA 4WVBA 3GZKA 3LZ9A 4DODA 4WU0A 4LNGB 1NXCA 1G9JA 5AGDA 1L2AA 4OJZA 2F6DA 1H54A 4KTPA 2H6HB 1LF6A 4ZG8A 3M71A 1GAIA 2WIIB 1SA5B 4GTMB 5DHKA 3M7CA 4DOEA 3KQ4A 4KKIA 4AYRA 1QSJA 3WIWA 4YDOB 5ILDA 2D5JA 4YCRA 3RSYA 4J5TA 1H35A 5ILYA 1O6QA 3H3KA 1WU6A 3M73A 4ZH1A 2H6FB 3M7BA 2J5CA 3WKIA 1WZZA 4DI5A 4OK4A 2RI8A 3PMMA 5M7YA 1HXCA 1GXNA 2DRRA 3EZ8A 4Z4LA 1X1IA 5GW7A 3SDTA 1HMUA 1FO3A 4QT9A 5DGQA 1V7WA 1N22A 1RWCA 1QAZA 1F9GA 3NNBA 1F9OA 1DCEB 2V8KA 1IA6A 1DL2A 2EADA 2BB5A 2WYNA 3GT5A 1O1TB 4MU9A 4RNQA 2DRQA 1GXMA 5IK6A 2CQSA 4Z4JA 4V1RA 1D8DB 1J0MA 4MMIA 2H6GB 3M78A 1GSZA 1S64B 1FMIA 5CA3A 3Q73B 1CLCA 1X1HA 2V8IA 1V7VA 2DRSA 2Z07A 1FBOA 3M77A 5ILKA 1TNBB 3TF4A 1LXMA 1CB8A 1TNZB 1I8QA 3QXFA 1AGMA 1FBWA 1KKTA 1NC5A 3OXUA 4YDEB 4D4CA 5GY3A 5IKAA 3KLSA 5IKHA 3EU5B 2IEJB 3S4AA 3SDVA 1LF9A 4LIXA 4Q2BA 3WKGA 2EACA 1H37A 3W7TA 2A73B 4LNBB 1KZOB 3GLYA 1UT9A 1HV6A 3RENA 3KSQB 3T33A 1FCEA 2BEDB 3SDQA 2ZISB 1TNYB 1TNOB 2V3NA 3S9VA 3Q79B 3QFYA 2D8LA 1ULVA 1LTXB 3HXCB 4F10A 3DPYB 2E22A 3P5RA 1N7QA 1QQFA 1RWAA 3E80A 3WKHA 3N0FA 3D3IA 1XW2A 1OJOA 1RWFA 3PYAA 5DGRA 2PN5A 2JF4A 1GHQA 3SFXB 1OJMA 4CE7A 4AYPA 1NI1B 3HXEB 2FV0A 4GTRB 3ACTA 2XWJB 3NFVA 4D4AA 1R76A 3VSMA 5IK0A 3QFZA 3W5MA 3SFYB 1OJNA 4L0GA 2WY8A 3QPFA 1O6HA 1UG9A 2DROA 1W6JA 3DRAB 2H6IB 3DSWB 1G6IA 3HXBB 3Q7AB 3SDUA 3SQCA 3RX8A 3PZ4B 1G9GA 1K72A 1IA7A 1IS9A 3P5PA 4GTVB 1TN8B 4AYQA 1N20A 2XQWA 2G02A 3ANIA 3HXDB 3PZ3B 2PMVA 4CJ0A 2EABA 2NVPA 2BRWA 2QNOA 4V1SA 2R2LB 2F0YB 1HM2A 2E24A 2WINB 1O5MB 1N4PB 4FUSA 2GH4A 3Q7FB 2JJBA 3QT9A 1O1RB 5ILHA 4D4BA 1KS8A 3KSLB 2BRVX 4ZRQA 2WDAA 5JMDA 2A8ZA 3WIRA 1N7OA 3W7SA 1WU4A 3H7LA 2FUZA 3VW5A 4GTTB 1N21A 4C1SA 3Q78B 3WC3A 3RRSA 2WY7A 1HN0A 4WVCA 3E34B 3W5NA 1CEMA 3N0GA 2WCOA 3VSNA 3RJ3A 3W7XA 1HCUA 3M72A 2ONHA 1H3CA 3QRYA 1GAHA 4JJJA 3DSUB 2XFGA 1N7NA 1N9AB 1C3DA 1XWQA 4CJ1A 1WU5A 4GL3A 4GTPB 1N7PA 4FJQA 1OJPA 5EAUA 3G4FA 1KZPB 1RQ5A 3DSSB 5M7IA 2VN7A 2BB6A 4BOKA 2NOJA 2FUTA 4L9PB 4E1YA 5FO7B 1LD8B 1O1SB 4OK2A 5CD2A 1TN6B 4FNVA 1KSDA 1N4QB 3CIHA 1S63B 3ACSA 3PZ2B 2OKXA 5ILIA 1HXAA 2B39A 5E2JA 1O6RA 1EGUA 3EU8A 2Q1FA 3OEDA 3M74A 2FBAA 3WIQA 4OZWA 3HXFB 3DSVB 3PZ1B 1RWGA 1LOHA 3DSXB 2XWBB 3QT3A 2V3PA 1VD5A 3SAEA 3W7UA 4KTRA 3M7EA 4GTQB 1X1JA 2AHFA 1HXGA 3PYBA 3X17A 1KWFA 3AFLA 2ZBLA 1GA2A 1TN7B 4GTOB 3M7LA 1DOGA 5IL3A 3ANKA 4EHMB 1LD7B 3ANJA 1L1YA 4FXGB 5FOBB 5FO8B 5C05A 4AYOA 2FV1A 1KFGA 3QDEA 2ONGA 1V5DA 4M76A 1D8EB 1F1SA 1FPPB 1HMWA 1N24A 5EATA 1JCQB 3E33B 1H3BA 1HM3A 1QBQB 4F13A 3M75A 1KRFA 4NEIA 4TF4A 1V7XA 3Q75B 1JCRB 3S4DA 3K11A 1NL4B 3QG0A 3WUXA 2ZZRA 1N94B 2V8JA 2JG0A 4ZRPA 5JPNB 3RX7A 5ILJA 1H13A 3M00A 3QXQA 1N4RB
chains in the Genus database with same CATH topology
2G0DA 1FT2B 5CZLA 3W7WA 2GZ6A 1MZCB 3S4CA 1H39A 1HZFA 4D4DA 1XWTA 3QWTA 1JS4A 3CU7A 1AYXA 4WVAA 5GZKA 4GTSB 1G87A 1FAEA 3D5SA 3SDRA 1UMPA 3K7XA 1KREA 1FO2A 2AFAA 2YIKA 4Q88A 1KSCA 3WKFA 1O79A 4LNVA 3D5RA 2CQTA 1F9DA 1W6KA 1H36A 4TXTA 5MEHA 1N4SB 4EL8A 5KKBA 4D94A 3M76A 2SQCA 1GXOA 3EUVB 4ZH5A 3DSTB 1TF4A 3C72B 2RGKA 4L6XA 1H3AA 3E30B 3E73A 2VN4A 2I07B 2AHGA 3E32B 3RX5A 1SQCA 1H14A 3A3VA 4ONTA 4FXKB 1JCSB 2GOXA 1FP3A 1SA4B 1V5CA 1N95B 3E6UA 3VXDA 4XUVA 2B4FA 3E37B 3P2CA 3S4BA 1X9DA 1X81B 3AFJA 1FT1B 1TNUB 5FO9B 2P0VA 3EQAA 4MBGB 1GLMA 2ZIRB 3G6JB 1H12A 4KKJA 3ON6A 2BBCA 4BOJA 2EAEA 2RI9A 3H2WA 5JPMB 3QSPA 4WVBA 3GZKA 4DODA 4WU0A 4LNGB 1NXCA 1G9JA 5AGDA 1L2AA 2F6DA 1H54A 4KTPA 2H6HB 1LF6A 4ZG8A 3M71A 1GAIA 2WIIB 1SA5B 4GTMB 4DOEA 3M7CA 3KQ4A 4KKIA 4AYRA 1QSJA 3WIWA 4YDOB 2D5JA 4YCRA 3RSYA 4J5TA 1H35A 1O6QA 3H3KA 1WU6A 3M73A 4ZH1A 2H6FB 3M7BA 3WKIA 1WZZA 2RI8A 3PMMA 5M7YA 1GXNA 2DRRA 3EZ8A 4Z4LA 5GW7A 3SDTA 1FO3A 4QT9A 5DGQA 1V7WA 1F9OA 1DCEB 2V8KA 1IA6A 1DL2A 2EADA 2BB5A 2WYNA 3GT5A 1O1TB 4MU9A 2DRQA 1GXMA 2CQSA 4Z4JA 4V1RA 1D8DB 2H6GB 3M78A 1GSZA 1S64B 1FMIA 5CA3A 3Q73B 1CLCA 2V8IA 1V7VA 2DRSA 2Z07A 1FBOA 3M77A 1TNBB 3TF4A 1TNZB 3QXFA 1AGMA 1FBWA 1KKTA 1NC5A 3OXUA 4YDEB 4D4CA 5GY3A 3KLSA 3EU5B 2IEJB 3S4AA 3SDVA 1LF9A 4LIXA 4Q2BA 3WKGA 2EACA 1H37A 3W7TA 2A73B 4LNBB 1KZOB 3GLYA 1UT9A 3RENA 3KSQB 3T33A 1FCEA 2BEDB 3SDQA 2ZISB 1TNYB 1TNOB 2V3NA 3S9VA 3Q79B 3QFYA 2D8LA 1ULVA 1LTXB 3HXCB 3DPYB 3P5RA 1QQFA 3WKHA 3D3IA 1XW2A 3PYAA 5DGRA 2PN5A 2JF4A 1GHQA 3SFXB 4CE7A 4AYPA 1NI1B 3HXEB 2FV0A 4GTRB 3ACTA 2XWJB 4D4AA 1R76A 3QFZA 3W5MA 3SFYB 4L0GA 2WY8A 3QPFA 1O6HA 1UG9A 2DROA 1W6JA 3DRAB 2H6IB 3DSWB 1G6IA 3HXBB 3Q7AB 3SDUA 3SQCA 3RX8A 3PZ4B 1G9GA 1K72A 1IA7A 1IS9A 3P5PA 4GTVB 1TN8B 4AYQA 2XQWA 2G02A 3ANIA 3HXDB 3PZ3B 2PMVA 4CJ0A 2EABA 2NVPA 4V1SA 2QNOA 2R2LB 2F0YB 2WINB 1O5MB 1N4PB 4FUSA 2GH4A 3Q7FB 2JJBA 3QT9A 1O1RB 4D4BA 1KS8A 3KSLB 4ZRQA 2A8ZA 3WIRA 3W7SA 1WU4A 3H7LA 2FUZA 3VW5A 4GTTB 4C1SA 3Q78B 3WC3A 3RRSA 2WY7A 4WVCA 3E34B 3W5NA 1CEMA 3RJ3A 3W7XA 1HCUA 3M72A 1H3CA 3QRYA 1GAHA 4JJJA 3DSUB 2XFGA 1N9AB 1C3DA 1XWQA 4CJ1A 1WU5A 4GL3A 4GTPB 1KZPB 1RQ5A 3DSSB 5M7IA 2VN7A 2BB6A 4BOKA 2NOJA 4L9PB 5FO7B 1LD8B 1O1SB 5CD2A 1TN6B 1KSDA 1N4QB 3CIHA 1S63B 3ACSA 3PZ2B 2OKXA 2B39A 5E2JA 1O6RA 3EU8A 3OEDA 3M74A 2FBAA 3WIQA 3HXFB 3DSVB 3PZ1B 3DSXB 2XWBB 3QT3A 2V3PA 1VD5A 3SAEA 3W7UA 4KTRA 3M7EA 4GTQB 2AHFA 3PYBA 3X17A 1KWFA 2ZBLA 1GA2A 1TN7B 4GTOB 3M7LA 1DOGA 3ANKA 4EHMB 1LD7B 3ANJA 1L1YA 4FXGB 5FOBB 5FO8B 4AYOA 2FV1A 1KFGA 3QDEA 1V5DA 4M76A 1D8EB 1FPPB 1JCQB 3E33B 1H3BA 1QBQB 3M75A 1KRFA 4TF4A 1V7XA 3Q75B 1JCRB 3S4DA 3K11A 1NL4B 3QG0A 3WUXA 2ZZRA 1N94B 2V8JA 2JG0A 4ZRPA 5JPNB 3RX7A 1H13A 3QXQA 1N4RB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2G0D A;  1C3D A;  3KSQ B;  1FT2 B;  4LNG B;  2BED B;  1MZC B;  5AGD A;  2ZIS B;  1H39 A;  1TNO B;  1HZF A;  1TNY B;  2V3N A;  4GTP B;  4D4D A;  3Q79 B;  3CU7 A;  2H6H B;  1KZP B;  1LTX B;  3HXC B;  3DPY B;  3DSS B;  1QQF A;  4GTS B;  2BB6 A;  2WII B;  4BOK A;  2NOJ A;  1SA5 B;  4GTM B;  4L9P B;  3KQ4 A;  5FO7 B;  1LD8 B;  2PN5 A;  3D5S A;  1GHQ A;  3SFX B;  1O1S B;  1UMP A;  4KKI A;  1QSJ A;  1TN6 B;  3K7X A;  1NI1 B;  3HXE B;  4YDO B;  4GTR B;  1N4Q B;  2XWJ B;  4D4A A;  1S63 B;  1R76 A;  1H35 A;  3SFY B;  3PZ2 B;  1O6Q A;  2WY8 A;  4ZH1 A;  1O6H A;  2H6F B;  2B39 A;  1O6R A;  1W6J A;  3DRA B;  2H6I B;  1O79 A;  4LNV A;  3OED A;  3D5R A;  3DSW B;  3HXB B;  3Q7A B;  1GXN A;  1W6K A;  3HXF B;  3DSV B;  1H36 A;  3SQC A;  3PZ1 B;  3PZ4 B;  3DSX B;  2XWB B;  1N4S B;  4GTV B;  4D94 A;  2V3P A;  1TN8 B;  2SQC A;  2XQW A;  2G02 A;  1GXO A;  3HXD B;  3PZ3 B;  2V8K A;  1DCE B;  2PMV A;  3EUV B;  2BB5 A;  3DST B;  3C72 B;  1O1T B;  4GTQ B;  4MU9 A;  1H3A A;  4V1S A;  1GXM A;  3E30 B;  2R2L B;  2F0Y B;  2WIN B;  1O5M B;  1N4P B;  4V1R A;  2I07 B;  1D8D B;  3E32 B;  2H6G B;  1GSZ A;  1S64 B;  1SQC A;  1TN7 B;  4GTO B;  4ONT A;  3Q7F B;  3Q73 B;  1O1R B;  4FXK B;  1LD7 B;  4EHM B;  1JCS B;  2GOX A;  4D4B A;  1SA4 B;  1N95 B;  2V8I A;  3KSL B;  4ZRQ A;  4FXG B;  5FOB B;  5FO8 B;  1TNB B;  3E37 B;  4M76 A;  1TNZ B;  1D8E B;  1FPP B;  3OXU A;  1X81 B;  4YDE B;  4D4C A;  4GTT B;  1JCQ B;  1FT1 B;  1H3B A;  1TNU B;  1QBQ B;  3E33 B;  4C1S A;  3Q78 B;  5FO9 B;  3KLS A;  2WY7 A;  3EU5 B;  4MBG B;  2IEJ B;  2ZIR B;  3G6J B;  3E34 B;  3Q75 B;  1JCR B;  4KKJ A;  3RJ3 A;  1NL4 B;  2BBC A;  1H37 A;  4BOJ A;  2A73 B;  4LNB B;  1N94 B;  2V8J A;  1KZO B;  4ZRP A;  5JPM B;  1H3C A;  5JPN B;  3DSU B;  1N4R B;  1N9A B; 
#chains in the Genus database with same CATH topology
 2G0D A;  1FT2 B;  5CZL A;  3W7W A;  2GZ6 A;  1MZC B;  3S4C A;  1H39 A;  1HZF A;  4D4D A;  1XWT A;  3QWT A;  1JS4 A;  3CU7 A;  1RWH A;  1AYX A;  4WVA A;  5GZK A;  4MMH A;  4GTS B;  4GAX A;  1G87 A;  1FAE A;  3M01 A;  1LXK A;  3D5S A;  3SDR A;  1J0N A;  1UMP A;  3K7X A;  1KRE A;  1N23 A;  1N7R A;  1W3Y A;  1RW9 A;  1FO2 A;  3A0O A;  2AFA A;  2YIK A;  4Q88 A;  1KSC A;  3WKF A;  1O79 A;  4LNV A;  3D5R A;  2CQT A;  1F9D A;  1W6K A;  1H36 A;  4TXT A;  5IL8 A;  5MEH A;  1N4S B;  5JMF A;  4EL8 A;  5KKB A;  4D94 A;  1HX9 A;  5EAS A;  3M76 A;  2SQC A;  1GXO A;  1N1B A;  2FUQ A;  3E7J A;  3EUV B;  4ZH5 A;  3DST B;  1TF4 A;  3C72 B;  2RGK A;  4L6X A;  3M02 A;  1H3A A;  3E30 B;  3E73 A;  2VN4 A;  5IM1 A;  2I07 B;  2AHG A;  4OZV A;  3E32 B;  1N1Z A;  3RX5 A;  1SQC A;  1H14 A;  3A3V A;  4ONT A;  4FXK B;  3G4D A;  1JCS B;  2GOX A;  2BRP A;  1FP3 A;  1SA4 B;  1V5C A;  1N95 B;  3E6U A;  5DHI A;  3VXD A;  4XUV A;  2B4F A;  3E37 B;  3P2C A;  3S4B A;  5ILZ A;  1X9D A;  1X81 B;  2X03 A;  3AFJ A;  1FT1 B;  1TNU B;  1C82 A;  5FO9 B;  2P0V A;  3EQA A;  4MBG B;  1GLM A;  2ZIR B;  3G6J B;  1H12 A;  4KKJ A;  3ON6 A;  5IK9 A;  2BBC A;  4BOJ A;  2EAE A;  2RI9 A;  3H2W A;  5JPM B;  3QSP A;  4WVB A;  3GZK A;  3LZ9 A;  4DOD A;  4WU0 A;  4LNG B;  1NXC A;  1G9J A;  5AGD A;  1L2A A;  4OJZ A;  2F6D A;  1H54 A;  4KTP A;  2H6H B;  1LF6 A;  4ZG8 A;  3M71 A;  1GAI A;  2WII B;  1SA5 B;  4GTM B;  5DHK A;  3M7C A;  4DOE A;  3KQ4 A;  4KKI A;  4AYR A;  1QSJ A;  3WIW A;  4YDO B;  5ILD A;  2D5J A;  4YCR A;  3RSY A;  4J5T A;  1H35 A;  5ILY A;  1O6Q A;  3H3K A;  1WU6 A;  3M73 A;  4ZH1 A;  2H6F B;  3M7B A;  2J5C A;  3WKI A;  1WZZ A;  4DI5 A;  4OK4 A;  2RI8 A;  3PMM A;  5M7Y A;  1HXC A;  1GXN A;  2DRR A;  3EZ8 A;  4Z4L A;  1X1I A;  5GW7 A;  3SDT A;  1HMU A;  1FO3 A;  4QT9 A;  5DGQ A;  1V7W A;  1N22 A;  1RWC A;  1QAZ A;  1F9G A;  3NNB A;  1F9O A;  1DCE B;  2V8K A;  1IA6 A;  1DL2 A;  2EAD A;  2BB5 A;  2WYN A;  3GT5 A;  1O1T B;  4MU9 A;  4RNQ A;  2DRQ A;  1GXM A;  5IK6 A;  2CQS A;  4Z4J A;  4V1R A;  1D8D B;  1J0M A;  4MMI A;  2H6G B;  3M78 A;  1GSZ A;  1S64 B;  1FMI A;  5CA3 A;  3Q73 B;  1CLC A;  1X1H A;  2V8I A;  1V7V A;  2DRS A;  2Z07 A;  1FBO A;  3M77 A;  5ILK A;  1TNB B;  3TF4 A;  1LXM A;  1CB8 A;  1TNZ B;  1I8Q A;  3QXF A;  1AGM A;  1FBW A;  1KKT A;  1NC5 A;  3OXU A;  4YDE B;  4D4C A;  5GY3 A;  5IKA A;  3KLS A;  5IKH A;  3EU5 B;  2IEJ B;  3S4A A;  3SDV A;  1LF9 A;  4LIX A;  4Q2B A;  3WKG A;  2EAC A;  1H37 A;  3W7T A;  2A73 B;  4LNB B;  1KZO B;  3GLY A;  1UT9 A;  1HV6 A;  3REN A;  3KSQ B;  3T33 A;  1FCE A;  2BED B;  3SDQ A;  2ZIS B;  1TNY B;  1TNO B;  2V3N A;  3S9V A;  3Q79 B;  3QFY A;  2D8L A;  1ULV A;  1LTX B;  3HXC B;  4F10 A;  3DPY B;  2E22 A;  3P5R A;  1N7Q A;  1QQF A;  1RWA A;  3E80 A;  3WKH A;  3N0F A;  3D3I A;  1XW2 A;  1OJO A;  1RWF A;  3PYA A;  5DGR A;  2PN5 A;  2JF4 A;  1GHQ A;  3SFX B;  1OJM A;  4CE7 A;  4AYP A;  1NI1 B;  3HXE B;  2FV0 A;  4GTR B;  3ACT A;  2XWJ B;  3NFV A;  4D4A A;  1R76 A;  3VSM A;  5IK0 A;  3QFZ A;  3W5M A;  3SFY B;  1OJN A;  4L0G A;  2WY8 A;  3QPF A;  1O6H A;  1UG9 A;  2DRO A;  1W6J A;  3DRA B;  2H6I B;  3DSW B;  1G6I A;  3HXB B;  3Q7A B;  3SDU A;  3SQC A;  3RX8 A;  3PZ4 B;  1G9G A;  1K72 A;  1IA7 A;  1IS9 A;  3P5P A;  4GTV B;  1TN8 B;  4AYQ A;  1N20 A;  2XQW A;  2G02 A;  3ANI A;  3HXD B;  3PZ3 B;  2PMV A;  4CJ0 A;  2EAB A;  2NVP A;  2BRW A;  2QNO A;  4V1S A;  2R2L B;  2F0Y B;  1HM2 A;  2E24 A;  2WIN B;  1O5M B;  1N4P B;  4FUS A;  2GH4 A;  3Q7F B;  2JJB A;  3QT9 A;  1O1R B;  5ILH A;  4D4B A;  1KS8 A;  3KSL B;  2BRV X;  4ZRQ A;  2WDA A;  5JMD A;  2A8Z A;  3WIR A;  1N7O A;  3W7S A;  1WU4 A;  3H7L A;  2FUZ A;  3VW5 A;  4GTT B;  1N21 A;  4C1S A;  3Q78 B;  3WC3 A;  3RRS A;  2WY7 A;  1HN0 A;  4WVC A;  3E34 B;  3W5N A;  1CEM A;  3N0G A;  2WCO A;  3VSN A;  3RJ3 A;  3W7X A;  1HCU A;  3M72 A;  2ONH A;  1H3C A;  3QRY A;  1GAH A;  4JJJ A;  3DSU B;  2XFG A;  1N7N A;  1N9A B;  1C3D A;  1XWQ A;  4CJ1 A;  1WU5 A;  4GL3 A;  4GTP B;  1N7P A;  4FJQ A;  1OJP A;  5EAU A;  3G4F A;  1KZP B;  1RQ5 A;  3DSS B;  5M7I A;  2VN7 A;  2BB6 A;  4BOK A;  2NOJ A;  2FUT A;  4L9P B;  4E1Y A;  5FO7 B;  1LD8 B;  1O1S B;  4OK2 A;  5CD2 A;  1TN6 B;  4FNV A;  1KSD A;  1N4Q B;  3CIH A;  1S63 B;  3ACS A;  3PZ2 B;  2OKX A;  5ILI A;  1HXA A;  2B39 A;  5E2J A;  1O6R A;  1EGU A;  3EU8 A;  2Q1F A;  3OED A;  3M74 A;  2FBA A;  3WIQ A;  4OZW A;  3HXF B;  3DSV B;  3PZ1 B;  1RWG A;  1LOH A;  3DSX B;  2XWB B;  3QT3 A;  2V3P A;  1VD5 A;  3SAE A;  3W7U A;  4KTR A;  3M7E A;  4GTQ B;  1X1J A;  2AHF A;  1HXG A;  3PYB A;  3X17 A;  1KWF A;  3AFL A;  2ZBL A;  1GA2 A;  1TN7 B;  4GTO B;  3M7L A;  1DOG A;  5IL3 A;  3ANK A;  4EHM B;  1LD7 B;  3ANJ A;  1L1Y A;  4FXG B;  5FOB B;  5FO8 B;  5C05 A;  4AYO A;  2FV1 A;  1KFG A;  3QDE A;  2ONG A;  1V5D A;  4M76 A;  1D8E B;  1F1S A;  1FPP B;  1HMW A;  1N24 A;  5EAT A;  1JCQ B;  3E33 B;  1H3B A;  1HM3 A;  1QBQ B;  4F13 A;  3M75 A;  1KRF A;  4NEI A;  4TF4 A;  1V7X A;  3Q75 B;  1JCR B;  3S4D A;  3K11 A;  1NL4 B;  3QG0 A;  3WUX A;  2ZZR A;  1N94 B;  2V8J A;  2JG0 A;  4ZRP A;  5JPN B;  3RX7 A;  5ILJ A;  1H13 A;  3M00 A;  3QXQ A;  1N4R B; 
#chains in the Genus database with same CATH homology
 2G0D A;  1FT2 B;  5CZL A;  3W7W A;  2GZ6 A;  1MZC B;  3S4C A;  1H39 A;  1HZF A;  4D4D A;  1XWT A;  3QWT A;  1JS4 A;  3CU7 A;  1AYX A;  4WVA A;  5GZK A;  4GTS B;  1G87 A;  1FAE A;  3D5S A;  3SDR A;  1UMP A;  3K7X A;  1KRE A;  1FO2 A;  2AFA A;  2YIK A;  4Q88 A;  1KSC A;  3WKF A;  1O79 A;  4LNV A;  3D5R A;  2CQT A;  1F9D A;  1W6K A;  1H36 A;  4TXT A;  5MEH A;  1N4S B;  4EL8 A;  5KKB A;  4D94 A;  3M76 A;  2SQC A;  1GXO A;  3EUV B;  4ZH5 A;  3DST B;  1TF4 A;  3C72 B;  2RGK A;  4L6X A;  1H3A A;  3E30 B;  3E73 A;  2VN4 A;  2I07 B;  2AHG A;  3E32 B;  3RX5 A;  1SQC A;  1H14 A;  3A3V A;  4ONT A;  4FXK B;  1JCS B;  2GOX A;  1FP3 A;  1SA4 B;  1V5C A;  1N95 B;  3E6U A;  3VXD A;  4XUV A;  2B4F A;  3E37 B;  3P2C A;  3S4B A;  1X9D A;  1X81 B;  3AFJ A;  1FT1 B;  1TNU B;  5FO9 B;  2P0V A;  3EQA A;  4MBG B;  1GLM A;  2ZIR B;  3G6J B;  1H12 A;  4KKJ A;  3ON6 A;  2BBC A;  4BOJ A;  2EAE A;  2RI9 A;  3H2W A;  5JPM B;  3QSP A;  4WVB A;  3GZK A;  4DOD A;  4WU0 A;  4LNG B;  1NXC A;  1G9J A;  5AGD A;  1L2A A;  2F6D A;  1H54 A;  4KTP A;  2H6H B;  1LF6 A;  4ZG8 A;  3M71 A;  1GAI A;  2WII B;  1SA5 B;  4GTM B;  4DOE A;  3M7C A;  3KQ4 A;  4KKI A;  4AYR A;  1QSJ A;  3WIW A;  4YDO B;  2D5J A;  4YCR A;  3RSY A;  4J5T A;  1H35 A;  1O6Q A;  3H3K A;  1WU6 A;  3M73 A;  4ZH1 A;  2H6F B;  3M7B A;  3WKI A;  1WZZ A;  2RI8 A;  3PMM A;  5M7Y A;  1GXN A;  2DRR A;  3EZ8 A;  4Z4L A;  5GW7 A;  3SDT A;  1FO3 A;  4QT9 A;  5DGQ A;  1V7W A;  1F9O A;  1DCE B;  2V8K A;  1IA6 A;  1DL2 A;  2EAD A;  2BB5 A;  2WYN A;  3GT5 A;  1O1T B;  4MU9 A;  2DRQ A;  1GXM A;  2CQS A;  4Z4J A;  4V1R A;  1D8D B;  2H6G B;  3M78 A;  1GSZ A;  1S64 B;  1FMI A;  5CA3 A;  3Q73 B;  1CLC A;  2V8I A;  1V7V A;  2DRS A;  2Z07 A;  1FBO A;  3M77 A;  1TNB B;  3TF4 A;  1TNZ B;  3QXF A;  1AGM A;  1FBW A;  1KKT A;  1NC5 A;  3OXU A;  4YDE B;  4D4C A;  5GY3 A;  3KLS A;  3EU5 B;  2IEJ B;  3S4A A;  3SDV A;  1LF9 A;  4LIX A;  4Q2B A;  3WKG A;  2EAC A;  1H37 A;  3W7T A;  2A73 B;  4LNB B;  1KZO B;  3GLY A;  1UT9 A;  3REN A;  3KSQ B;  3T33 A;  1FCE A;  2BED B;  3SDQ A;  2ZIS B;  1TNY B;  1TNO B;  2V3N A;  3S9V A;  3Q79 B;  3QFY A;  2D8L A;  1ULV A;  1LTX B;  3HXC B;  3DPY B;  3P5R A;  1QQF A;  3WKH A;  3D3I A;  1XW2 A;  3PYA A;  5DGR A;  2PN5 A;  2JF4 A;  1GHQ A;  3SFX B;  4CE7 A;  4AYP A;  1NI1 B;  3HXE B;  2FV0 A;  4GTR B;  3ACT A;  2XWJ B;  4D4A A;  1R76 A;  3QFZ A;  3W5M A;  3SFY B;  4L0G A;  2WY8 A;  3QPF A;  1O6H A;  1UG9 A;  2DRO A;  1W6J A;  3DRA B;  2H6I B;  3DSW B;  1G6I A;  3HXB B;  3Q7A B;  3SDU A;  3SQC A;  3RX8 A;  3PZ4 B;  1G9G A;  1K72 A;  1IA7 A;  1IS9 A;  3P5P A;  4GTV B;  1TN8 B;  4AYQ A;  2XQW A;  2G02 A;  3ANI A;  3HXD B;  3PZ3 B;  2PMV A;  4CJ0 A;  2EAB A;  2NVP A;  4V1S A;  2QNO A;  2R2L B;  2F0Y B;  2WIN B;  1O5M B;  1N4P B;  4FUS A;  2GH4 A;  3Q7F B;  2JJB A;  3QT9 A;  1O1R B;  4D4B A;  1KS8 A;  3KSL B;  4ZRQ A;  2A8Z A;  3WIR A;  3W7S A;  1WU4 A;  3H7L A;  2FUZ A;  3VW5 A;  4GTT B;  4C1S A;  3Q78 B;  3WC3 A;  3RRS A;  2WY7 A;  4WVC A;  3E34 B;  3W5N A;  1CEM A;  3RJ3 A;  3W7X A;  1HCU A;  3M72 A;  1H3C A;  3QRY A;  1GAH A;  4JJJ A;  3DSU B;  2XFG A;  1N9A B;  1C3D A;  1XWQ A;  4CJ1 A;  1WU5 A;  4GL3 A;  4GTP B;  1KZP B;  1RQ5 A;  3DSS B;  5M7I A;  2VN7 A;  2BB6 A;  4BOK A;  2NOJ A;  4L9P B;  5FO7 B;  1LD8 B;  1O1S B;  5CD2 A;  1TN6 B;  1KSD A;  1N4Q B;  3CIH A;  1S63 B;  3ACS A;  3PZ2 B;  2OKX A;  2B39 A;  5E2J A;  1O6R A;  3EU8 A;  3OED A;  3M74 A;  2FBA A;  3WIQ A;  3HXF B;  3DSV B;  3PZ1 B;  3DSX B;  2XWB B;  3QT3 A;  2V3P A;  1VD5 A;  3SAE A;  3W7U A;  4KTR A;  3M7E A;  4GTQ B;  2AHF A;  3PYB A;  3X17 A;  1KWF A;  2ZBL A;  1GA2 A;  1TN7 B;  4GTO B;  3M7L A;  1DOG A;  3ANK A;  4EHM B;  1LD7 B;  3ANJ A;  1L1Y A;  4FXG B;  5FOB B;  5FO8 B;  4AYO A;  2FV1 A;  1KFG A;  3QDE A;  1V5D A;  4M76 A;  1D8E B;  1FPP B;  1JCQ B;  3E33 B;  1H3B A;  1QBQ B;  3M75 A;  1KRF A;  4TF4 A;  1V7X A;  3Q75 B;  1JCR B;  3S4D A;  3K11 A;  1NL4 B;  3QG0 A;  3WUX A;  2ZZR A;  1N94 B;  2V8J A;  2JG0 A;  4ZRP A;  5JPN B;  3RX7 A;  1H13 A;  3QXQ A;  1N4R B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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