1NI1B

Imidazole and cyanophenyl farnesyl transferase inhibitors
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
401
structure length
401
Chain Sequence
LYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Protein farnesyltransferase alpha subunit
publication title Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Transferase
total genus 137
structure length 401
sequence length 401
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2002-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1ni1B00
3PZ1B 4LNVA 2I07B 3KSLB 1O5MB 2IEJB 1O6HA 4MU9A 1O6RA 2PMVA 4D4CA 1H37A 1O79A 1NI1B 1JCQB 1W6KA 1QSJA 1O6QA 2V8IA 1N9AB 4FXGB 4KKJA 3SFXB 1O1TB 2V8KA 4D4DA 4L9PB 1TNOB 1LTXB 4LNGB 1GSZA 2V3NA 4GTRB 4GTTB 3Q73B 4ZRPA 1FT2B 4GTVB 2H6GB 1LD8B 1R76A 1GXMA 3Q7FB 3Q75B 4GTSB 1H35A 2BB6A 2BEDB 2ZISB 4EHMB 5FOBB 1LD7B 1O1SB 3D5SA 1GXOA 2PN5A 4GTOB 2V8JA 3SFYB 4C1SA 1S64B 2XWJB 1TNYB 3HXCB 4D94A 1KZPB 1FPPB 1MZCB 2XWBB 1TN6B 2BBCA 1O1RB 2NOJA 3E33B 1TNBB 2F0YB 2ZIRB 4GTPB 3DSWB 1QBQB 5JPMB 3G6JB 1UMPA 5FO8B 3E37B 3E30B 1W6JA 3Q78B 4LNBB 1D8DB 2BB5A 4BOKA 1GXNA 3K7XA 2R2LB 3KQ4A 5FO7B 4ZH1A 3KSQB 3E32B 1FT1B 4MBGB 2H6HB 1TN7B 1JCSB 3EUVB 4GTMB 1NL4B 1TNZB 1H3CA 2XQWA 4V1RA 3RJ3A 5FO9B 1H3AA 3D5RA 3CU7A 1H39A 1TNUB 1SA4B 1DCEB 1N95B 2B39A 4ZRQA 3Q79B 3DRAB 1N4PB 3PZ4B 3DPYB 4FXKB 3SQCA 3DSSB 1D8EB 1HZFA 1N94B 3DSUB 3E34B 1N4QB 4D4AA 5AGDA 3OEDA 5JPNB 1X81B 1C3DA 1QQFA 1TN8B 2G02A 4YDOB 1SQCA 2H6FB 2WY7A 3KLSA 4V1SA 3HXDB 3HXFB 4BOJA 2V3PA 1SA5B 3DSTB 1H36A 2GOXA 1GHQA 1KZOB 3Q7AB 3PZ2B 3DSXB 4ONTA 4KKIA 1S63B 4D4BA 2SQCA 2A73B 2WIIB 1N4SB 3DSVB 4GTQB 3OXUA 4YDEB 2WINB 2G0DA 1JCRB 3C72B 3HXEB 3HXBB 3EU5B 1N4RB 2H6IB 3PZ3B 2WY8A 4M76A 1H3BA
chains in the Genus database with same CATH superfamily
2ZBLA 1FAEA 3PZ1B 2RI8A 1G87A 2I07B 5JMDA 4MU9A 2PMVA 1V7VA 3VSNA 1W6KA 1N9AB 1LF9A 2V8KA 1TNOB 1FBOA 3P5RA 1XWTA 3VXDA 3Q73B 5IL3A 4ZRPA 1DOGA 2H6GB 1GXMA 4F13A 3QSPA 5MEHA 2BB6A 2BEDB 2AHGA 4CJ0A 1LD7B 4F10A 2AHFA 5DGRA 5GY3A 5KKBA 1OJNA 4GTOB 2V8JA 3SFYB 3E73A 3HXCB 1LF6A 1UG9A 1KZPB 2YIKA 3QDEA 2BBCA 1W3YA 3N0GA 2GH4A 5CA3A 1O1RB 2DRSA 1QBQB 3G6JB 1UMPA 5FO8B 3W7SA 3E30B 2WCOA 4OZVA 2EACA 3E80A 1UT9A 3K7XA 2EAEA 5FO7B 1FO2A 3E32B 3KSQB 5IK0A 1C82A 1HN0A 1FT1B 1V7WA 3E7JA 3EUVB 4L6XA 1KSCA 3AFJA 1H3CA 1HXCA 3D5RA 2VN4A 1KFGA 4AYPA 1V5DA 3G4DA 3PYAA 1FCEA 3DRAB 3EU8A 3ON6A 3ANKA 1HXAA 3GZKA 3PZ4B 3DPYB 4FXKB 3W7UA 1HZFA 1N94B 2XFGA 3M71A 1CEMA 4D4AA 1QQFA 2FUQA 3WIQA 1SQCA 4J5TA 4V1SA 3RX7A 3HXDB 3HXFB 4BOJA 4AYQA 3DSTB 2GOXA 1KZOB 2E22A 3M73A 4OZWA 3SDRA 1GAHA 5JMFA 4Q2BA 1DL2A 1S63B 2SQCA 2A73B 4D4BA 1N4SB 3DSVB 3OXUA 2WINB 3C72B 3HXEB 3M7LA 3WKHA 2H6IB 2DRRA 5IKHA 2WY8A 1H3BA 3M00A 3KSLB 1IA6A 2F6DA 3NNBA 1KS8A 2A8ZA 1O6HA 5GW7A 1O79A 1QSJA 4WVCA 1WZZA 4D4DA 4L9PB 1AYXA 4QT9A 3EQAA 3S4CA 1GSZA 4GTRB 5ILDA 1NXCA 1FT2B 1ULVA 3Q75B 4GTSB 1N23A 1GLMA 2CQSA 1F9OA 4EHMB 3S4DA 2JG0A 1O1SB 3S4AA 1GA2A 1S64B 3TF4A 5ILJA 1FP3A 1FPPB 4FUSA 4KTPA 3RX5A 4DI5A 1TN6B 1J0MA 2FV0A 5EASA 3E33B 2NOJA 1G6IA 3S9VA 1V5CA 2ZIRB 4GTPB 5IM1A 3E6UA 3H7LA 1XW2A 1W6JA 2CQTA 3M7EA 4ZH1A 3D3IA 5ILIA 4MBGB 3W7TA 5CD2A 4CE7A 1JCSB 1IS9A 4XUVA 2VN7A 1FMIA 1TNZB 3N0FA 1TF4A 5FO9B 5IK6A 1H12A 1K72A 1V7XA 2B39A 2AFAA 1OJOA 3DSSB 2FBAA 4WU0A 1N7QA 1RWFA 5AGDA 1LOHA 3OEDA 4ZG8A 1C3DA 4L0GA 3WC3A 2G02A 4MMHA 2H6FB 2WY7A 3M77A 2FUZA 3H2WA 3W7XA 2V3PA 2WYNA 1X1HA 1KWFA 3ANJA 2D5JA 1G9GA 1N1BA 4Z4LA 3PZ2B 4ONTA 2P0VA 4KKIA 4DODA 2FUTA 2WIIB 4GTQB 3VSMA 2DRQA 3QFYA 1JCRB 1F9DA 1HV6A 3M76A 3X17A 2JF4A 1N4RB 1N7PA 2BRWA 1L1YA 3WKGA 3K11A 3PMMA 1O6RA 3WKIA 4D4CA 1H37A 1KRFA 1NI1B 4OK4A 2V8IA 4KKJA 3QT3A 1RWCA 5DHIA 5M7YA 4LNGB 3QXFA 3PYBA 4GTTB 1I8QA 4ZH5A 2GZ6A 1LD8B 1R76A 3Q7FB 3GLYA 1H35A 4FJQA 2ZISB 3W7WA 4M76A 2E24A 4LIXA 3D5SA 1GXOA 2PN5A 5ILZA 4E1YA 2XWBB 1RWAA 4KTRA 5EATA 3VW5A 4OK2A 3SDQA 4WVBA 4Q88A 2BB5A 5GZKA 4BOKA 1XWQA 1GXNA 4AYRA 1RWHA 2EABA 2H6HB 4RNQA 1TN7B 3WUXA 1CB8A 3T33A 2XQWA 3RJ3A 3M78A 1AGMA 5E2JA 3LZ9A 3RSYA 3RRSA 1X1JA 1HXGA 3CU7A 3S4BA 3QXQA 3A0OA 1TNUB 2EADA 1N7NA 3SDTA 4ZRQA 2B4FA 3M02A 1N4PB 3ACTA 2RI9A 1HX9A 1HM2A 1G9JA 1L2AA 1RQ5A 1F1SA 1OJMA 1N4QB 2BRPA 5JPNB 2J5CA 1H14A 1X81B 1TN8B 2ONGA 3KLSA 1KREA 5IKAA 1FBWA 3P5PA 1H36A 3M7BA 1GHQA 4FNVA 1RWGA 2OKXA 2X03A 3SAEA 3DSXB 3P2CA 3AFLA 2QNOA 3M74A 4TF4A 1N24A 1N20A 1N7RA 1J0NA 2ONHA 3WIWA 3EU5B 4LNVA 3RENA 4JJJA 1O5MB 1KSDA 1HMWA 2IEJB 1JCQB 4FXGB 1O6QA 3SFXB 1O1TB 1HM3A 1RW9A 3W5MA 1LTXB 2V3NA 5C05A 3H3KA 2JJBA 5ILYA 5IK9A 4GTVB 3EZ8A 1QAZA 5FOBB 3M72A 5CZLA 2ZZRA 4C1SA 1X9DA 2XWJB 1VD5A 1TNYB 1LXMA 1N7OA 4D94A 1MZCB 4WVAA 3M75A 1IA7A 1LXKA 4DOEA 1JS4A 3M01A 3NFVA 1F9GA 1TNBB 1HMUA 2F0YB 2WDAA 4EL8A 3DSWB 3GT5A 5EAUA 5JPMB 4GAXA 3E37B 1H54A 3QPFA 3Q78B 4LNBB 1D8DB 2DROA 1WU5A 2R2LB 3KQ4A 4MMIA 4CJ1A 1HCUA 1GAIA 3QG0A 1N22A 3SDVA 4GTMB 1NC5A 1NL4B 5DGQA 4OJZA 2BRVX 4V1RA 3QFZA 1H3AA 3M7CA 3QRYA 2Q1FA 1H39A 3A3VA 1SA4B 3QT9A 1DCEB 1N95B 3QWTA 5M7IA 3Q79B 3SDUA 5ILHA 1OJPA 3SQCA 1N21A 2D8LA 2FV1A 1D8EB 3ANIA 3DSUB 3E34B 3WKFA 1X1IA 4YDOB 1WU6A 1H13A 4YCRA 4Z4JA 4NEIA 3G4FA 1SA5B 3Q7AB 2Z07A 2RGKA 5ILKA 1KKTA 1CLCA 1WU4A 3WIRA 2NVPA 3RX8A 1N1ZA 4AYOA 3W5NA 4YDEB 5DHKA 2G0DA 1FO3A 3CIHA 4TXTA 3HXBB 3ACSA 3PZ3B 5IL8A 1EGUA 4GL3A
chains in the Genus database with same CATH topology
2ZBLA 1FAEA 3PZ1B 2RI8A 1G87A 2I07B 4MU9A 2PMVA 1V7VA 1W6KA 1N9AB 1LF9A 2V8KA 1TNOB 1FBOA 3P5RA 1XWTA 3VXDA 3Q73B 4ZRPA 1DOGA 2H6GB 1GXMA 3QSPA 5MEHA 2BB6A 2BEDB 2AHGA 4CJ0A 1LD7B 2AHFA 5DGRA 5GY3A 5KKBA 4GTOB 2V8JA 3SFYB 3E73A 3HXCB 1LF6A 1UG9A 1KZPB 2YIKA 3QDEA 2BBCA 2GH4A 5CA3A 1O1RB 2DRSA 1QBQB 3G6JB 1UMPA 5FO8B 3W7SA 3E30B 2EACA 1UT9A 3K7XA 2EAEA 5FO7B 1FO2A 3E32B 3KSQB 1FT1B 1V7WA 3EUVB 4L6XA 1KSCA 3AFJA 1H3CA 3D5RA 2VN4A 1KFGA 4AYPA 1V5DA 3PYAA 1FCEA 3DRAB 3EU8A 3ON6A 3ANKA 3GZKA 3PZ4B 3DPYB 4FXKB 3W7UA 1HZFA 1N94B 2XFGA 3M71A 1CEMA 4D4AA 1QQFA 3WIQA 1SQCA 4J5TA 4V1SA 3RX7A 3HXDB 3HXFB 4BOJA 4AYQA 3DSTB 2GOXA 1KZOB 3M73A 3SDRA 1GAHA 4Q2BA 1DL2A 1S63B 2SQCA 2A73B 4D4BA 1N4SB 3DSVB 3OXUA 2WINB 3C72B 3HXEB 3M7LA 3WKHA 2H6IB 2DRRA 2WY8A 1H3BA 3KSLB 1IA6A 2F6DA 1KS8A 2A8ZA 1O6HA 5GW7A 1O79A 1QSJA 4WVCA 1WZZA 4D4DA 4L9PB 1AYXA 4QT9A 3EQAA 3S4CA 1GSZA 4GTRB 1NXCA 1FT2B 1ULVA 3Q75B 4GTSB 1GLMA 2CQSA 1F9OA 4EHMB 3S4DA 2JG0A 1O1SB 3S4AA 1GA2A 1S64B 3TF4A 1FP3A 1FPPB 4FUSA 4KTPA 3RX5A 1TN6B 2FV0A 2NOJA 1G6IA 3E33B 3S9VA 1V5CA 2ZIRB 4GTPB 3E6UA 3H7LA 1XW2A 1W6JA 2CQTA 3M7EA 4ZH1A 3D3IA 4MBGB 3W7TA 5CD2A 4CE7A 1JCSB 1IS9A 4XUVA 2VN7A 1FMIA 1TNZB 1TF4A 5FO9B 1H12A 1K72A 1V7XA 2B39A 2AFAA 3DSSB 2FBAA 4WU0A 5AGDA 3OEDA 4ZG8A 1C3DA 4L0GA 3WC3A 2G02A 2H6FB 2WY7A 3M77A 2FUZA 3H2WA 3W7XA 2V3PA 2WYNA 1KWFA 2D5JA 3ANJA 1G9GA 4Z4LA 3PZ2B 4ONTA 2P0VA 4KKIA 4DODA 2WIIB 4GTQB 2DRQA 3QFYA 1JCRB 1F9DA 3M76A 3X17A 2JF4A 1N4RB 1L1YA 3WKGA 3K11A 3PMMA 1O6RA 3WKIA 4D4CA 1H37A 1KRFA 1NI1B 2V8IA 4KKJA 3QT3A 5M7YA 4LNGB 3QXFA 3PYBA 4GTTB 4ZH5A 2GZ6A 1LD8B 1R76A 3Q7FB 3GLYA 1H35A 2ZISB 3W7WA 4M76A 4LIXA 3D5SA 1GXOA 2PN5A 2XWBB 4KTRA 3VW5A 3SDQA 4WVBA 4Q88A 2BB5A 5GZKA 4BOKA 1XWQA 1GXNA 4AYRA 2EABA 2H6HB 1TN7B 3WUXA 3T33A 2XQWA 3RJ3A 3M78A 1AGMA 5E2JA 3RSYA 3RRSA 3CU7A 3S4BA 3QXQA 1TNUB 2EADA 3SDTA 4ZRQA 2B4FA 1N4PB 3ACTA 2RI9A 1G9JA 1L2AA 1RQ5A 1N4QB 5JPNB 1H14A 1X81B 1TN8B 3KLSA 1KREA 1FBWA 3P5PA 3M7BA 1H36A 1GHQA 2OKXA 3SAEA 3DSXB 3P2CA 2QNOA 3M74A 4TF4A 3WIWA 3EU5B 4LNVA 3RENA 4JJJA 1O5MB 1KSDA 2IEJB 1JCQB 4FXGB 1O6QA 3SFXB 1O1TB 3W5MA 1LTXB 2V3NA 3H3KA 2JJBA 4GTVB 3EZ8A 5FOBB 3M72A 5CZLA 2ZZRA 4C1SA 1X9DA 2XWJB 1VD5A 1TNYB 4D94A 1MZCB 4WVAA 3M75A 1IA7A 4DOEA 1JS4A 1TNBB 2F0YB 4EL8A 3DSWB 3GT5A 5JPMB 3E37B 1H54A 3QPFA 3Q78B 4LNBB 1D8DB 2DROA 1WU5A 2R2LB 3KQ4A 4CJ1A 1HCUA 1GAIA 3QG0A 3SDVA 4GTMB 1NC5A 1NL4B 5DGQA 4V1RA 3QFZA 1H3AA 3M7CA 3QRYA 1H39A 3A3VA 1SA4B 3QT9A 1DCEB 1N95B 3QWTA 5M7IA 3Q79B 3SDUA 3SQCA 2D8LA 2FV1A 1D8EB 3ANIA 3DSUB 3E34B 3WKFA 4YDOB 1WU6A 1H13A 4YCRA 4Z4JA 1SA5B 3Q7AB 2RGKA 2Z07A 1KKTA 1CLCA 1WU4A 3WIRA 2NVPA 3RX8A 4AYOA 3W5NA 4YDEB 2G0DA 1FO3A 3CIHA 4TXTA 3HXBB 3ACSA 3PZ3B 4GL3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PZ1 B;  4LNV A;  2I07 B;  3KSL B;  1O5M B;  2IEJ B;  1O6H A;  4MU9 A;  1O6R A;  2PMV A;  4D4C A;  1H37 A;  1O79 A;  1NI1 B;  1JCQ B;  1W6K A;  1QSJ A;  1O6Q A;  2V8I A;  1N9A B;  4FXG B;  4KKJ A;  3SFX B;  1O1T B;  2V8K A;  4D4D A;  4L9P B;  1TNO B;  1LTX B;  4LNG B;  1GSZ A;  2V3N A;  4GTR B;  4GTT B;  3Q73 B;  4ZRP A;  1FT2 B;  4GTV B;  2H6G B;  1LD8 B;  1R76 A;  1GXM A;  3Q7F B;  3Q75 B;  4GTS B;  1H35 A;  2BB6 A;  2BED B;  2ZIS B;  4EHM B;  5FOB B;  1LD7 B;  1O1S B;  3D5S A;  1GXO A;  2PN5 A;  4GTO B;  2V8J A;  3SFY B;  4C1S A;  1S64 B;  2XWJ B;  1TNY B;  3HXC B;  4D94 A;  1KZP B;  1FPP B;  1MZC B;  2XWB B;  1TN6 B;  2BBC A;  1O1R B;  2NOJ A;  3E33 B;  1TNB B;  2F0Y B;  2ZIR B;  4GTP B;  3DSW B;  1QBQ B;  5JPM B;  3G6J B;  1UMP A;  5FO8 B;  3E37 B;  3E30 B;  1W6J A;  3Q78 B;  4LNB B;  1D8D B;  2BB5 A;  4BOK A;  1GXN A;  3K7X A;  2R2L B;  3KQ4 A;  5FO7 B;  4ZH1 A;  3KSQ B;  3E32 B;  1FT1 B;  4MBG B;  2H6H B;  1TN7 B;  1JCS B;  3EUV B;  4GTM B;  1NL4 B;  1TNZ B;  1H3C A;  2XQW A;  4V1R A;  3RJ3 A;  5FO9 B;  1H3A A;  3D5R A;  3CU7 A;  1H39 A;  1TNU B;  1SA4 B;  1DCE B;  1N95 B;  2B39 A;  4ZRQ A;  3Q79 B;  3DRA B;  1N4P B;  3PZ4 B;  3DPY B;  4FXK B;  3SQC A;  3DSS B;  1D8E B;  1HZF A;  1N94 B;  3DSU B;  3E34 B;  1N4Q B;  4D4A A;  5AGD A;  3OED A;  5JPN B;  1X81 B;  1C3D A;  1QQF A;  1TN8 B;  2G02 A;  4YDO B;  1SQC A;  2H6F B;  2WY7 A;  3KLS A;  4V1S A;  3HXD B;  3HXF B;  4BOJ A;  2V3P A;  1SA5 B;  3DST B;  1H36 A;  2GOX A;  1GHQ A;  1KZO B;  3Q7A B;  3PZ2 B;  3DSX B;  4ONT A;  4KKI A;  1S63 B;  4D4B A;  2SQC A;  2A73 B;  2WII B;  1N4S B;  3DSV B;  4GTQ B;  3OXU A;  4YDE B;  2WIN B;  2G0D A;  1JCR B;  3C72 B;  3HXE B;  3HXB B;  3EU5 B;  1N4R B;  2H6I B;  3PZ3 B;  2WY8 A;  4M76 A;  1H3B A; 
#chains in the Genus database with same CATH topology
 2ZBL A;  1FAE A;  3PZ1 B;  2RI8 A;  1G87 A;  2I07 B;  5JMD A;  4MU9 A;  2PMV A;  1V7V A;  3VSN A;  1W6K A;  1N9A B;  1LF9 A;  2V8K A;  1TNO B;  1FBO A;  3P5R A;  1XWT A;  3VXD A;  3Q73 B;  5IL3 A;  4ZRP A;  1DOG A;  2H6G B;  1GXM A;  4F13 A;  3QSP A;  5MEH A;  2BB6 A;  2BED B;  2AHG A;  4CJ0 A;  1LD7 B;  4F10 A;  2AHF A;  5DGR A;  5GY3 A;  5KKB A;  1OJN A;  4GTO B;  2V8J A;  3SFY B;  3E73 A;  3HXC B;  1LF6 A;  1UG9 A;  1KZP B;  2YIK A;  3QDE A;  2BBC A;  1W3Y A;  3N0G A;  2GH4 A;  5CA3 A;  1O1R B;  2DRS A;  1QBQ B;  3G6J B;  1UMP A;  5FO8 B;  3W7S A;  3E30 B;  2WCO A;  4OZV A;  2EAC A;  3E80 A;  1UT9 A;  3K7X A;  2EAE A;  5FO7 B;  1FO2 A;  3E32 B;  3KSQ B;  5IK0 A;  1C82 A;  1HN0 A;  1FT1 B;  1V7W A;  3E7J A;  3EUV B;  4L6X A;  1KSC A;  3AFJ A;  1H3C A;  1HXC A;  3D5R A;  2VN4 A;  1KFG A;  4AYP A;  1V5D A;  3G4D A;  3PYA A;  1FCE A;  3DRA B;  3EU8 A;  3ON6 A;  3ANK A;  1HXA A;  3GZK A;  3PZ4 B;  3DPY B;  4FXK B;  3W7U A;  1HZF A;  1N94 B;  2XFG A;  3M71 A;  1CEM A;  4D4A A;  1QQF A;  2FUQ A;  3WIQ A;  1SQC A;  4J5T A;  4V1S A;  3RX7 A;  3HXD B;  3HXF B;  4BOJ A;  4AYQ A;  3DST B;  2GOX A;  1KZO B;  2E22 A;  3M73 A;  4OZW A;  3SDR A;  1GAH A;  5JMF A;  4Q2B A;  1DL2 A;  1S63 B;  2SQC A;  2A73 B;  4D4B A;  1N4S B;  3DSV B;  3OXU A;  2WIN B;  3C72 B;  3HXE B;  3M7L A;  3WKH A;  2H6I B;  2DRR A;  5IKH A;  2WY8 A;  1H3B A;  3M00 A;  3KSL B;  1IA6 A;  2F6D A;  3NNB A;  1KS8 A;  2A8Z A;  1O6H A;  5GW7 A;  1O79 A;  1QSJ A;  4WVC A;  1WZZ A;  4D4D A;  4L9P B;  1AYX A;  4QT9 A;  3EQA A;  3S4C A;  1GSZ A;  4GTR B;  5ILD A;  1NXC A;  1FT2 B;  1ULV A;  3Q75 B;  4GTS B;  1N23 A;  1GLM A;  2CQS A;  1F9O A;  4EHM B;  3S4D A;  2JG0 A;  1O1S B;  3S4A A;  1GA2 A;  1S64 B;  3TF4 A;  5ILJ A;  1FP3 A;  1FPP B;  4FUS A;  4KTP A;  3RX5 A;  4DI5 A;  1TN6 B;  1J0M A;  2FV0 A;  5EAS A;  3E33 B;  2NOJ A;  1G6I A;  3S9V A;  1V5C A;  2ZIR B;  4GTP B;  5IM1 A;  3E6U A;  3H7L A;  1XW2 A;  1W6J A;  2CQT A;  3M7E A;  4ZH1 A;  3D3I A;  5ILI A;  4MBG B;  3W7T A;  5CD2 A;  4CE7 A;  1JCS B;  1IS9 A;  4XUV A;  2VN7 A;  1FMI A;  1TNZ B;  3N0F A;  1TF4 A;  5FO9 B;  5IK6 A;  1H12 A;  1K72 A;  1V7X A;  2B39 A;  2AFA A;  1OJO A;  3DSS B;  2FBA A;  4WU0 A;  1N7Q A;  1RWF A;  5AGD A;  1LOH A;  3OED A;  4ZG8 A;  1C3D A;  4L0G A;  3WC3 A;  2G02 A;  4MMH A;  2H6F B;  2WY7 A;  3M77 A;  2FUZ A;  3H2W A;  3W7X A;  2V3P A;  2WYN A;  1X1H A;  1KWF A;  3ANJ A;  2D5J A;  1G9G A;  1N1B A;  4Z4L A;  3PZ2 B;  4ONT A;  2P0V A;  4KKI A;  4DOD A;  2FUT A;  2WII B;  4GTQ B;  3VSM A;  2DRQ A;  3QFY A;  1JCR B;  1F9D A;  1HV6 A;  3M76 A;  3X17 A;  2JF4 A;  1N4R B;  1N7P A;  2BRW A;  1L1Y A;  3WKG A;  3K11 A;  3PMM A;  1O6R A;  3WKI A;  4D4C A;  1H37 A;  1KRF A;  1NI1 B;  4OK4 A;  2V8I A;  4KKJ A;  3QT3 A;  1RWC A;  5DHI A;  5M7Y A;  4LNG B;  3QXF A;  3PYB A;  4GTT B;  1I8Q A;  4ZH5 A;  2GZ6 A;  1LD8 B;  1R76 A;  3Q7F B;  3GLY A;  1H35 A;  4FJQ A;  2ZIS B;  3W7W A;  4M76 A;  2E24 A;  4LIX A;  3D5S A;  1GXO A;  2PN5 A;  5ILZ A;  4E1Y A;  2XWB B;  1RWA A;  4KTR A;  5EAT A;  3VW5 A;  4OK2 A;  3SDQ A;  4WVB A;  4Q88 A;  2BB5 A;  5GZK A;  4BOK A;  1XWQ A;  1GXN A;  4AYR A;  1RWH A;  2EAB A;  2H6H B;  4RNQ A;  1TN7 B;  3WUX A;  1CB8 A;  3T33 A;  2XQW A;  3RJ3 A;  3M78 A;  1AGM A;  5E2J A;  3LZ9 A;  3RSY A;  3RRS A;  1X1J A;  1HXG A;  3CU7 A;  3S4B A;  3QXQ A;  3A0O A;  1TNU B;  2EAD A;  1N7N A;  3SDT A;  4ZRQ A;  2B4F A;  3M02 A;  1N4P B;  3ACT A;  2RI9 A;  1HX9 A;  1HM2 A;  1G9J A;  1L2A A;  1RQ5 A;  1F1S A;  1OJM A;  1N4Q B;  2BRP A;  5JPN B;  2J5C A;  1H14 A;  1X81 B;  1TN8 B;  2ONG A;  3KLS A;  1KRE A;  5IKA A;  1FBW A;  3P5P A;  1H36 A;  3M7B A;  1GHQ A;  4FNV A;  1RWG A;  2OKX A;  2X03 A;  3SAE A;  3DSX B;  3P2C A;  3AFL A;  2QNO A;  3M74 A;  4TF4 A;  1N24 A;  1N20 A;  1N7R A;  1J0N A;  2ONH A;  3WIW A;  3EU5 B;  4LNV A;  3REN A;  4JJJ A;  1O5M B;  1KSD A;  1HMW A;  2IEJ B;  1JCQ B;  4FXG B;  1O6Q A;  3SFX B;  1O1T B;  1HM3 A;  1RW9 A;  3W5M A;  1LTX B;  2V3N A;  5C05 A;  3H3K A;  2JJB A;  5ILY A;  5IK9 A;  4GTV B;  3EZ8 A;  1QAZ A;  5FOB B;  3M72 A;  5CZL A;  2ZZR A;  4C1S A;  1X9D A;  2XWJ B;  1VD5 A;  1TNY B;  1LXM A;  1N7O A;  4D94 A;  1MZC B;  4WVA A;  3M75 A;  1IA7 A;  1LXK A;  4DOE A;  1JS4 A;  3M01 A;  3NFV A;  1F9G A;  1TNB B;  1HMU A;  2F0Y B;  2WDA A;  4EL8 A;  3DSW B;  3GT5 A;  5EAU A;  5JPM B;  4GAX A;  3E37 B;  1H54 A;  3QPF A;  3Q78 B;  4LNB B;  1D8D B;  2DRO A;  1WU5 A;  2R2L B;  3KQ4 A;  4MMI A;  4CJ1 A;  1HCU A;  1GAI A;  3QG0 A;  1N22 A;  3SDV A;  4GTM B;  1NC5 A;  1NL4 B;  5DGQ A;  4OJZ A;  2BRV X;  4V1R A;  3QFZ A;  1H3A A;  3M7C A;  3QRY A;  2Q1F A;  1H39 A;  3A3V A;  1SA4 B;  3QT9 A;  1DCE B;  1N95 B;  3QWT A;  5M7I A;  3Q79 B;  3SDU A;  5ILH A;  1OJP A;  3SQC A;  1N21 A;  2D8L A;  2FV1 A;  1D8E B;  3ANI A;  3DSU B;  3E34 B;  3WKF A;  1X1I A;  4YDO B;  1WU6 A;  1H13 A;  4YCR A;  4Z4J A;  4NEI A;  3G4F A;  1SA5 B;  3Q7A B;  2Z07 A;  2RGK A;  5ILK A;  1KKT A;  1CLC A;  1WU4 A;  3WIR A;  2NVP A;  3RX8 A;  1N1Z A;  4AYO A;  3W5N A;  4YDE B;  5DHK A;  2G0D A;  1FO3 A;  3CIH A;  4TXT A;  3HXB B;  3ACS A;  3PZ3 B;  5IL8 A;  1EGU A;  4GL3 A; 
#chains in the Genus database with same CATH homology
 2ZBL A;  1FAE A;  3PZ1 B;  2RI8 A;  1G87 A;  2I07 B;  4MU9 A;  2PMV A;  1V7V A;  1W6K A;  1N9A B;  1LF9 A;  2V8K A;  1TNO B;  1FBO A;  3P5R A;  1XWT A;  3VXD A;  3Q73 B;  4ZRP A;  1DOG A;  2H6G B;  1GXM A;  3QSP A;  5MEH A;  2BB6 A;  2BED B;  2AHG A;  4CJ0 A;  1LD7 B;  2AHF A;  5DGR A;  5GY3 A;  5KKB A;  4GTO B;  2V8J A;  3SFY B;  3E73 A;  3HXC B;  1LF6 A;  1UG9 A;  1KZP B;  2YIK A;  3QDE A;  2BBC A;  2GH4 A;  5CA3 A;  1O1R B;  2DRS A;  1QBQ B;  3G6J B;  1UMP A;  5FO8 B;  3W7S A;  3E30 B;  2EAC A;  1UT9 A;  3K7X A;  2EAE A;  5FO7 B;  1FO2 A;  3E32 B;  3KSQ B;  1FT1 B;  1V7W A;  3EUV B;  4L6X A;  1KSC A;  3AFJ A;  1H3C A;  3D5R A;  2VN4 A;  1KFG A;  4AYP A;  1V5D A;  3PYA A;  1FCE A;  3DRA B;  3EU8 A;  3ON6 A;  3ANK A;  3GZK A;  3PZ4 B;  3DPY B;  4FXK B;  3W7U A;  1HZF A;  1N94 B;  2XFG A;  3M71 A;  1CEM A;  4D4A A;  1QQF A;  3WIQ A;  1SQC A;  4J5T A;  4V1S A;  3RX7 A;  3HXD B;  3HXF B;  4BOJ A;  4AYQ A;  3DST B;  2GOX A;  1KZO B;  3M73 A;  3SDR A;  1GAH A;  4Q2B A;  1DL2 A;  1S63 B;  2SQC A;  2A73 B;  4D4B A;  1N4S B;  3DSV B;  3OXU A;  2WIN B;  3C72 B;  3HXE B;  3M7L A;  3WKH A;  2H6I B;  2DRR A;  2WY8 A;  1H3B A;  3KSL B;  1IA6 A;  2F6D A;  1KS8 A;  2A8Z A;  1O6H A;  5GW7 A;  1O79 A;  1QSJ A;  4WVC A;  1WZZ A;  4D4D A;  4L9P B;  1AYX A;  4QT9 A;  3EQA A;  3S4C A;  1GSZ A;  4GTR B;  1NXC A;  1FT2 B;  1ULV A;  3Q75 B;  4GTS B;  1GLM A;  2CQS A;  1F9O A;  4EHM B;  3S4D A;  2JG0 A;  1O1S B;  3S4A A;  1GA2 A;  1S64 B;  3TF4 A;  1FP3 A;  1FPP B;  4FUS A;  4KTP A;  3RX5 A;  1TN6 B;  2FV0 A;  2NOJ A;  1G6I A;  3E33 B;  3S9V A;  1V5C A;  2ZIR B;  4GTP B;  3E6U A;  3H7L A;  1XW2 A;  1W6J A;  2CQT A;  3M7E A;  4ZH1 A;  3D3I A;  4MBG B;  3W7T A;  5CD2 A;  4CE7 A;  1JCS B;  1IS9 A;  4XUV A;  2VN7 A;  1FMI A;  1TNZ B;  1TF4 A;  5FO9 B;  1H12 A;  1K72 A;  1V7X A;  2B39 A;  2AFA A;  3DSS B;  2FBA A;  4WU0 A;  5AGD A;  3OED A;  4ZG8 A;  1C3D A;  4L0G A;  3WC3 A;  2G02 A;  2H6F B;  2WY7 A;  3M77 A;  2FUZ A;  3H2W A;  3W7X A;  2V3P A;  2WYN A;  1KWF A;  2D5J A;  3ANJ A;  1G9G A;  4Z4L A;  3PZ2 B;  4ONT A;  2P0V A;  4KKI A;  4DOD A;  2WII B;  4GTQ B;  2DRQ A;  3QFY A;  1JCR B;  1F9D A;  3M76 A;  3X17 A;  2JF4 A;  1N4R B;  1L1Y A;  3WKG A;  3K11 A;  3PMM A;  1O6R A;  3WKI A;  4D4C A;  1H37 A;  1KRF A;  1NI1 B;  2V8I A;  4KKJ A;  3QT3 A;  5M7Y A;  4LNG B;  3QXF A;  3PYB A;  4GTT B;  4ZH5 A;  2GZ6 A;  1LD8 B;  1R76 A;  3Q7F B;  3GLY A;  1H35 A;  2ZIS B;  3W7W A;  4M76 A;  4LIX A;  3D5S A;  1GXO A;  2PN5 A;  2XWB B;  4KTR A;  3VW5 A;  3SDQ A;  4WVB A;  4Q88 A;  2BB5 A;  5GZK A;  4BOK A;  1XWQ A;  1GXN A;  4AYR A;  2EAB A;  2H6H B;  1TN7 B;  3WUX A;  3T33 A;  2XQW A;  3RJ3 A;  3M78 A;  1AGM A;  5E2J A;  3RSY A;  3RRS A;  3CU7 A;  3S4B A;  3QXQ A;  1TNU B;  2EAD A;  3SDT A;  4ZRQ A;  2B4F A;  1N4P B;  3ACT A;  2RI9 A;  1G9J A;  1L2A A;  1RQ5 A;  1N4Q B;  5JPN B;  1H14 A;  1X81 B;  1TN8 B;  3KLS A;  1KRE A;  1FBW A;  3P5P A;  3M7B A;  1H36 A;  1GHQ A;  2OKX A;  3SAE A;  3DSX B;  3P2C A;  2QNO A;  3M74 A;  4TF4 A;  3WIW A;  3EU5 B;  4LNV A;  3REN A;  4JJJ A;  1O5M B;  1KSD A;  2IEJ B;  1JCQ B;  4FXG B;  1O6Q A;  3SFX B;  1O1T B;  3W5M A;  1LTX B;  2V3N A;  3H3K A;  2JJB A;  4GTV B;  3EZ8 A;  5FOB B;  3M72 A;  5CZL A;  2ZZR A;  4C1S A;  1X9D A;  2XWJ B;  1VD5 A;  1TNY B;  4D94 A;  1MZC B;  4WVA A;  3M75 A;  1IA7 A;  4DOE A;  1JS4 A;  1TNB B;  2F0Y B;  4EL8 A;  3DSW B;  3GT5 A;  5JPM B;  3E37 B;  1H54 A;  3QPF A;  3Q78 B;  4LNB B;  1D8D B;  2DRO A;  1WU5 A;  2R2L B;  3KQ4 A;  4CJ1 A;  1HCU A;  1GAI A;  3QG0 A;  3SDV A;  4GTM B;  1NC5 A;  1NL4 B;  5DGQ A;  4V1R A;  3QFZ A;  1H3A A;  3M7C A;  3QRY A;  1H39 A;  3A3V A;  1SA4 B;  3QT9 A;  1DCE B;  1N95 B;  3QWT A;  5M7I A;  3Q79 B;  3SDU A;  3SQC A;  2D8L A;  2FV1 A;  1D8E B;  3ANI A;  3DSU B;  3E34 B;  3WKF A;  4YDO B;  1WU6 A;  1H13 A;  4YCR A;  4Z4J A;  1SA5 B;  3Q7A B;  2RGK A;  2Z07 A;  1KKT A;  1CLC A;  1WU4 A;  3WIR A;  2NVP A;  3RX8 A;  4AYO A;  3W5N A;  4YDE B;  2G0D A;  1FO3 A;  3CIH A;  4TXT A;  3HXB B;  3ACS A;  3PZ3 B;  4GL3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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