1NI1B

Imidazole and cyanophenyl farnesyl transferase inhibitors
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
401
structure length
401
Chain Sequence
LYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Protein farnesyltransferase alpha subunit
publication title Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 137
structure length 401
sequence length 401
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2002-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1ni1B00
3E37B 1N9AB 1N94B 3DSTB 1NI1B 4LNBB 4C1SA 5JPNB 3PZ1B 1JCRB 1DCEB 3D5SA 4MBGB 3DRAB 4FXKB 1QBQB 3HXCB 3KSQB 1O1TB 3K7XA 2V8JA 4GTPB 1W6JA 2GOXA 3DSWB 3PZ2B 4YDOB 3HXDB 1SQCA 4ZH1A 4ZRQA 1W6KA 4GTRB 1O6RA 3OEDA 2H6IB 1N4PB 4L9PB 4D4DA 5FO9B 1O1SB 3KSLB 4ZRPA 2V3PA 2WY7A 2H6GB 3C72B 3Q75B 2PN5A 1H36A 1TN8B 2I07B 4GTQB 1HZFA 5FO7B 1S63B 5FOBB 4D4AA 2V8IA 2H6HB 3E34B 4GTVB 3DPYB 3CU7A 1SA5B 3E33B 4D4BA 1UMPA 3HXEB 1O1RB 1LTXB 2BEDB 1N95B 3Q73B 3Q79B 4GTSB 1LD8B 4V1RA 5JPMB 2XWBB 1R76A 3HXFB 1D8DB 1O6QA 1C3DA 3SQCA 2H6FB 3E30B 3SFYB 4D4CA 2ZIRB 3DSSB 2BB5A 2WIIB 1N4SB 1TNBB 4KKIA 1TN7B 4M76A 3EUVB 2IEJB 1N4RB 2WY8A 3PZ4B 4EHMB 1S64B 1GSZA 1TN6B 2XQWA 4V1SA 3SFXB 1SA4B 2B39A 3HXBB 3E32B 3KQ4A 2R2LB 1TNYB 4GTTB 1O79A 4MU9A 1QSJA 2NOJA 3EU5B 3DSXB 1GXOA 3D5RA 3PZ3B 4GTMB 1FPPB 1O6HA 2ZISB 3DSVB 4LNVA 2PMVA 1GHQA 1KZPB 4KKJA 4BOKA 4LNGB 1H35A 2F0YB 4GTOB 1JCQB 1GXNA 1H3AA 2G02A 2V3NA 4ONTA 3G6JB 5AGDA 1D8EB 2WINB 1NL4B 1H3BA 2A73B 2G0DA 1FT1B 1JCSB 1KZOB 1N4QB 1QQFA 5FO8B 1H3CA 1H39A 1TNUB 2XWJB 1TNOB 3Q78B 3KLSA 3Q7FB 1GXMA 1FT2B 2BBCA 4YDEB 1MZCB 1O5MB 2BB6A 1TNZB 4FXGB 3OXUA 2V8KA 3DSUB 1LD7B 1H37A 3Q7AB 4D94A 3RJ3A 2SQCA 4BOJA 1X81B
chains in the Genus database with same CATH superfamily
1N94B 1NI1B 3PZ1B 1JCRB 1DCEB 2ONGA 3N0GA 3WKGA 2WDAA 4GTPB 3RENA 1W6JA 2GOXA 4ZH1A 1GLMA 4ZRQA 1HXGA 1LXKA 3ACTA 1UG9A 2H6IB 1V7XA 1RWHA 5ILYA 5ILZA 1H12A 4L9PB 3KSLB 2FUZA 2A8ZA 1KREA 3M77A 1IA7A 5DGRA 1V7WA 1AGMA 3C72B 1FBOA 2PN5A 3Q75B 3W5NA 2P0VA 3M7CA 3S9VA 5FO7B 2BRPA 3SDTA 4D4AA 2V8IA 1SA5B 1UMPA 1J0MA 1N7RA 3EZ8A 4KTRA 2BEDB 3M71A 4DI5A 1CLCA 1X9DA 3W7WA 2BRVX 3S4DA 1O6QA 3SQCA 1XWTA 4TXTA 4D4CA 1FCEA 3E7JA 3VW5A 1FO3A 2DROA 3EUVB 1GAIA 4WVBA 1CEMA 4CE7A 3SFXB 1SA4B 4AYRA 2DRRA 4OJZA 2JJBA 1HMWA 4GTTB 2QNOA 4MU9A 1QSJA 1XWQA 3DSXB 1GXOA 1KSCA 3PZ3B 4GTMB 1FPPB 1KZPB 3QXQA 3S4BA 1H35A 2VN4A 1RWGA 4OZVA 1H3AA 1WZZA 2V3NA 1C82A 1KSDA 3G6JB 5GZKA 4JJJA 4RNQA 1LXMA 1D8EB 2WINB 3M7BA 1FT1B 3QXFA 3M73A 1QQFA 5FO8B 1H3CA 5IL3A 3K11A 5EASA 1FT2B 1NC5A 4YDEB 1AYXA 3GLYA 2V8KA 3DSUB 4Q88A 3GT5A 2DRSA 2SQCA 2YIKA 3CIHA 1HM2A 2CQTA 4MBGB 5ILKA 3N0FA 4FXKB 1QBQB 3HXCB 3KSQB 4OZWA 2V8JA 1L1YA 2RI9A 2RI8A 3DSWB 1X1IA 3M7EA 3RSYA 3QT9A 1N7QA 1N1ZA 1RW9A 2WCOA 4WU0A 1NXCA 1QAZA 1TF4A 1WU5A 4ZRPA 2WY7A 1H36A 2I07B 1DOGA 1S63B 5IL8A 3DPYB 5IK0A 2VN7A 1H54A 1O1RB 1LTXB 5JMFA 1X1HA 1N24A 4QT9A 3ACSA 3Q73B 3W7SA 4TF4A 5JPMB 1N7PA 4GL3A 3M72A 1R76A 3HXFB 1D8DB 5IK6A 1C3DA 2H6FB 2EADA 3E30B 1XW2A 3DSSB 2BB5A 3WIRA 1TN7B 4OK2A 3WKFA 1HXAA 2WY8A 1WU4A 3QFZA 4EHMB 1FP3A 2XQWA 1WU6A 3S4CA 4NEIA 1FAEA 3HXBB 3E32B 5E2JA 1W3YA 1TNYB 3QFYA 5M7YA 3QG0A 3VXDA 2FV1A 5EATA 5DHIA 4GTOB 1GXNA 3QDEA 3PYAA 2GH4A 1RQ5A 4KTPA 4AYPA 1N4QB 1KZOB 1LF9A 4L6XA 1OJPA 3SDRA 1TNUB 1H39A 3T33A 4AYOA 1IA6A 2XWJB 3AFLA 1L2AA 1UT9A 4DODA 2BBCA 1MZCB 2BB6A 1J0NA 1VD5A 1LD7B 1H37A 2RGKA 3M76A 1G9JA 5DHKA 4XUVA 5JPNB 3DSTB 4LNBB 4C1SA 1LOHA 1X1JA 2D8LA 1OJNA 2Z07A 3D5SA 3DRAB 3K7XA 3G4FA 5IKAA 5GY3A 3PZ2B 1SQCA 3WKHA 3A0OA 4GTRB 3OEDA 2FUTA 1N4PB 4D4DA 5FO9B 3M75A 2V3PA 3SDVA 5ILDA 1KS8A 1G6IA 2H6GB 4WVAA 4Q2BA 3A3VA 4FNVA 1HZFA 4ZH5A 1HV6A 5GW7A 1F1SA 2F6DA 2XFGA 4CJ0A 3CU7A 1FBWA 3E33B 1FO2A 1G9GA 3HXEB 1G87A 2Q1FA 3RX8A 1F9DA 1N95B 1N23A 5IM1A 1LD8B 1ULVA 2B4FA 3P5PA 3SFYB 4OK4A 2ZIRB 3H3KA 1N4SB 1HN0A 1KRFA 3H7LA 2WYNA 1RWAA 2E22A 1JS4A 3PZ4B 3NFVA 4MMIA 1GSZA 4V1SA 3TF4A 3W7TA 2B39A 3VSMA 4FJQA 4Z4LA 2NOJA 5EAUA 3EU5B 2FV0A 3D5RA 4EL8A 1LF6A 2DRQA 3DSVB 1HM3A 2PMVA 1I8QA 2D5JA 3ANJA 2ZZRA 2JG0A 1JCQB 2G02A 4ONTA 1F9GA 3X17A 1RWFA 2FUQA 2NVPA 3ANIA 1NL4B 3H2WA 1H3BA 2A73B 2G0DA 5CZLA 1JCSB 3RRSA 5CD2A 4L0GA 3Q78B 3Q7FB 1H14A 2ZBLA 3SDQA 1GXMA 3WIQA 3PMMA 3D3IA 1O5MB 1GAHA 1TNZB 3QPFA 5ILJA 1HCUA 1N21A 3M7LA 3NNBA 4YCRA 3Q7AB 3WC3A 3RJ3A 1K72A 2EACA 3E37B 1N9AB 5IK9A 5CA3A 3W7XA 1OJOA 1N7NA 1O1TB 4Z4JA 3PYBA 4FUSA 5DGQA 3E80A 3QRYA 2E24A 1F9OA 4YDOB 3HXDB 2CQSA 3P2CA 1W6KA 2FBAA 3W5MA 1O6RA 1O1SB 3ANKA 1TN8B 1IS9A 4GTQB 3S4AA 2AHGA 3W7UA 5FOBB 1N20A 1HMUA 2H6HB 1HXCA 3E34B 4GTVB 2ONHA 4D4BA 1GA2A 1N1BA 3QT3A 2EAEA 1H13A 4J5TA 1DL2A 1KWFA 4GAXA 2BRWA 3Q79B 4GTSB 4F10A 4V1RA 3SDUA 2XWBB 3M00A 4DOEA 3P5RA 2GZ6A 4E1YA 3LZ9A 1V7VA 3M02A 2WIIB 1CB8A 1EGUA 1TNBB 3EQAA 4KKIA 1V5DA 4M76A 2IEJB 3M74A 1N4RB 3EU8A 1FMIA 1N7OA 1S64B 3M78A 5IKHA 1TN6B 2X03A 3VSNA 3ON6A 3WUXA 4F13A 1HX9A 2R2LB 3KQ4A 3E6UA 2EABA 1V5CA 1O79A 5KKBA 4ZG8A 2JF4A 1KKTA 4AYQA 3GZKA 1KFGA 1O6HA 2ZISB 4LNVA 5ILIA 3RX7A 1GHQA 4KKJA 3QSPA 4BOKA 4LNGB 4LIXA 3M01A 2F0YB 3WKIA 4WVCA 5AGDA 5C05A 1N22A 1OJMA 1RWCA 3E73A 1TNOB 3AFJA 3KLSA 5JMDA 4CJ1A 5M7IA 2AHFA 4MMHA 2OKXA 3QWTA 4FXGB 5ILHA 3OXUA 3G4DA 2AFAA 2J5CA 3WIWA 5MEHA 4D94A 3RX5A 4BOJA 3SAEA 1X81B
chains in the Genus database with same CATH topology
1N94B 1NI1B 3PZ1B 1JCRB 1DCEB 3WKGA 4GTPB 3RENA 1W6JA 2GOXA 4ZH1A 1GLMA 4ZRQA 3ACTA 1UG9A 2H6IB 1V7XA 1H12A 4L9PB 3KSLB 2FUZA 2A8ZA 1KREA 3M77A 1IA7A 5DGRA 1V7WA 1AGMA 3C72B 1FBOA 2PN5A 3Q75B 3W5NA 2P0VA 3M7CA 3S9VA 5FO7B 3SDTA 4D4AA 2V8IA 1SA5B 1UMPA 3EZ8A 4KTRA 2BEDB 3M71A 1CLCA 1X9DA 3W7WA 3S4DA 1O6QA 3SQCA 1XWTA 4TXTA 4D4CA 1FCEA 3VW5A 1FO3A 2DROA 3EUVB 1GAIA 4WVBA 1CEMA 4CE7A 3SFXB 1SA4B 4AYRA 2DRRA 2JJBA 4GTTB 2QNOA 4MU9A 1QSJA 1XWQA 3DSXB 1GXOA 1KSCA 3PZ3B 4GTMB 1FPPB 1KZPB 3QXQA 3S4BA 1H35A 2VN4A 1H3AA 1WZZA 2V3NA 1KSDA 3G6JB 5GZKA 4JJJA 1D8EB 2WINB 3M7BA 1FT1B 3QXFA 3M73A 1QQFA 5FO8B 1H3CA 3K11A 1FT2B 1NC5A 4YDEB 1AYXA 3GLYA 2V8KA 3DSUB 4Q88A 3GT5A 2DRSA 2SQCA 2YIKA 3CIHA 2CQTA 4MBGB 4FXKB 1QBQB 3HXCB 3KSQB 2V8JA 1L1YA 2RI9A 2RI8A 3DSWB 3M7EA 3RSYA 3QT9A 4WU0A 1NXCA 1WU5A 1TF4A 4ZRPA 2WY7A 1H36A 2I07B 1DOGA 1S63B 3DPYB 2VN7A 1H54A 1O1RB 1LTXB 4QT9A 3ACSA 3Q73B 3W7SA 4TF4A 5JPMB 4GL3A 3M72A 1R76A 3HXFB 1D8DB 1C3DA 2H6FB 2EADA 3E30B 1XW2A 3DSSB 2BB5A 3WIRA 1TN7B 3WKFA 2WY8A 1WU4A 3QFZA 4EHMB 1FP3A 2XQWA 1WU6A 3S4CA 1FAEA 3HXBB 3E32B 5E2JA 1TNYB 3QFYA 5M7YA 3QG0A 3VXDA 2FV1A 4GTOB 1GXNA 3QDEA 3PYAA 2GH4A 1RQ5A 4KTPA 4AYPA 1N4QB 1KZOB 1LF9A 4L6XA 3SDRA 1TNUB 1H39A 3T33A 4AYOA 1IA6A 2XWJB 1L2AA 1UT9A 4DODA 2BBCA 1MZCB 2BB6A 1VD5A 1LD7B 1H37A 2RGKA 3M76A 1G9JA 4XUVA 5JPNB 3DSTB 4LNBB 4C1SA 2D8LA 2Z07A 3D5SA 3DRAB 3K7XA 5GY3A 3PZ2B 1SQCA 3WKHA 4GTRB 3OEDA 1N4PB 4D4DA 5FO9B 3M75A 2V3PA 3SDVA 1KS8A 1G6IA 2H6GB 4WVAA 4Q2BA 3A3VA 1HZFA 4ZH5A 5GW7A 2XFGA 2F6DA 4CJ0A 3CU7A 1FBWA 3E33B 1FO2A 1G9GA 3HXEB 1G87A 3RX8A 1F9DA 1N95B 1LD8B 1ULVA 2B4FA 3P5PA 3SFYB 2ZIRB 3H3KA 1N4SB 1KRFA 3H7LA 2WYNA 1JS4A 3PZ4B 1GSZA 4V1SA 3TF4A 3W7TA 2B39A 4Z4LA 2NOJA 3EU5B 2FV0A 3D5RA 4EL8A 1LF6A 2DRQA 3DSVB 2PMVA 2D5JA 3ANJA 2ZZRA 2JG0A 1JCQB 2G02A 4ONTA 3X17A 2NVPA 3ANIA 1NL4B 3H2WA 1H3BA 2A73B 2G0DA 5CZLA 1JCSB 3RRSA 5CD2A 4L0GA 3Q78B 3Q7FB 1H14A 2ZBLA 3SDQA 1GXMA 3WIQA 3PMMA 3D3IA 1O5MB 1GAHA 1TNZB 3QPFA 1HCUA 3M7LA 4YCRA 3Q7AB 3WC3A 3RJ3A 1K72A 2EACA 3E37B 1N9AB 5CA3A 3W7XA 1O1TB 4Z4JA 3PYBA 4FUSA 5DGQA 3QRYA 1F9OA 4YDOB 3HXDB 2CQSA 3P2CA 1W6KA 2FBAA 3W5MA 1O6RA 1O1SB 3ANKA 1TN8B 1IS9A 4GTQB 3S4AA 2AHGA 3W7UA 5FOBB 2H6HB 3E34B 4GTVB 4D4BA 1GA2A 3QT3A 2EAEA 1H13A 4J5TA 1DL2A 1KWFA 3Q79B 4GTSB 4V1RA 3SDUA 2XWBB 4DOEA 3P5RA 2GZ6A 1V7VA 2WIIB 1TNBB 3EQAA 4KKIA 1V5DA 4M76A 2IEJB 3M74A 1N4RB 3EU8A 1FMIA 1S64B 3M78A 1TN6B 3ON6A 3WUXA 3KQ4A 2R2LB 3E6UA 2EABA 1V5CA 1O79A 5KKBA 4ZG8A 2JF4A 1KKTA 4AYQA 3GZKA 1KFGA 1O6HA 2ZISB 4LNVA 3RX7A 1GHQA 4KKJA 3QSPA 4BOKA 4LNGB 4LIXA 2F0YB 3WKIA 4WVCA 5AGDA 3E73A 1TNOB 3AFJA 3KLSA 4CJ1A 5M7IA 2AHFA 2OKXA 3QWTA 4FXGB 3OXUA 2AFAA 3WIWA 5MEHA 4D94A 3RX5A 4BOJA 3SAEA 1X81B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3E37 B;  1N9A B;  1N94 B;  3DST B;  1NI1 B;  4LNB B;  4C1S A;  5JPN B;  3PZ1 B;  1JCR B;  1DCE B;  3D5S A;  4MBG B;  3DRA B;  4FXK B;  1QBQ B;  3HXC B;  3KSQ B;  1O1T B;  3K7X A;  2V8J A;  4GTP B;  1W6J A;  2GOX A;  3DSW B;  3PZ2 B;  4YDO B;  3HXD B;  1SQC A;  4ZH1 A;  4ZRQ A;  1W6K A;  4GTR B;  1O6R A;  3OED A;  2H6I B;  1N4P B;  4L9P B;  4D4D A;  5FO9 B;  1O1S B;  3KSL B;  4ZRP A;  2V3P A;  2WY7 A;  2H6G B;  3C72 B;  3Q75 B;  2PN5 A;  1H36 A;  1TN8 B;  2I07 B;  4GTQ B;  1HZF A;  5FO7 B;  1S63 B;  5FOB B;  4D4A A;  2V8I A;  2H6H B;  3E34 B;  4GTV B;  3DPY B;  3CU7 A;  1SA5 B;  3E33 B;  4D4B A;  1UMP A;  3HXE B;  1O1R B;  1LTX B;  2BED B;  1N95 B;  3Q73 B;  3Q79 B;  4GTS B;  1LD8 B;  4V1R A;  5JPM B;  2XWB B;  1R76 A;  3HXF B;  1D8D B;  1O6Q A;  1C3D A;  3SQC A;  2H6F B;  3E30 B;  3SFY B;  4D4C A;  2ZIR B;  3DSS B;  2BB5 A;  2WII B;  1N4S B;  1TNB B;  4KKI A;  1TN7 B;  4M76 A;  3EUV B;  2IEJ B;  1N4R B;  2WY8 A;  3PZ4 B;  4EHM B;  1S64 B;  1GSZ A;  1TN6 B;  2XQW A;  4V1S A;  3SFX B;  1SA4 B;  2B39 A;  3HXB B;  3E32 B;  3KQ4 A;  2R2L B;  1TNY B;  4GTT B;  1O79 A;  4MU9 A;  1QSJ A;  2NOJ A;  3EU5 B;  3DSX B;  1GXO A;  3D5R A;  3PZ3 B;  4GTM B;  1FPP B;  1O6H A;  2ZIS B;  3DSV B;  4LNV A;  2PMV A;  1GHQ A;  1KZP B;  4KKJ A;  4BOK A;  4LNG B;  1H35 A;  2F0Y B;  4GTO B;  1JCQ B;  1GXN A;  1H3A A;  2G02 A;  2V3N A;  4ONT A;  3G6J B;  5AGD A;  1D8E B;  2WIN B;  1NL4 B;  1H3B A;  2A73 B;  2G0D A;  1FT1 B;  1JCS B;  1KZO B;  1N4Q B;  1QQF A;  5FO8 B;  1H3C A;  1H39 A;  1TNU B;  2XWJ B;  1TNO B;  3Q78 B;  3KLS A;  3Q7F B;  1GXM A;  1FT2 B;  2BBC A;  4YDE B;  1MZC B;  1O5M B;  2BB6 A;  1TNZ B;  4FXG B;  3OXU A;  2V8K A;  3DSU B;  1LD7 B;  1H37 A;  3Q7A B;  4D94 A;  3RJ3 A;  2SQC A;  4BOJ A;  1X81 B; 
#chains in the Genus database with same CATH topology
 1N94 B;  1NI1 B;  3PZ1 B;  1JCR B;  1DCE B;  2ONG A;  3N0G A;  3WKG A;  2WDA A;  4GTP B;  3REN A;  1W6J A;  2GOX A;  4ZH1 A;  1GLM A;  4ZRQ A;  1HXG A;  1LXK A;  3ACT A;  1UG9 A;  2H6I B;  1V7X A;  1RWH A;  5ILY A;  5ILZ A;  1H12 A;  4L9P B;  3KSL B;  2FUZ A;  2A8Z A;  1KRE A;  3M77 A;  1IA7 A;  5DGR A;  1V7W A;  1AGM A;  3C72 B;  1FBO A;  2PN5 A;  3Q75 B;  3W5N A;  2P0V A;  3M7C A;  3S9V A;  5FO7 B;  2BRP A;  3SDT A;  4D4A A;  2V8I A;  1SA5 B;  1UMP A;  1J0M A;  1N7R A;  3EZ8 A;  4KTR A;  2BED B;  3M71 A;  4DI5 A;  1CLC A;  1X9D A;  3W7W A;  2BRV X;  3S4D A;  1O6Q A;  3SQC A;  1XWT A;  4TXT A;  4D4C A;  1FCE A;  3E7J A;  3VW5 A;  1FO3 A;  2DRO A;  3EUV B;  1GAI A;  4WVB A;  1CEM A;  4CE7 A;  3SFX B;  1SA4 B;  4AYR A;  2DRR A;  4OJZ A;  2JJB A;  1HMW A;  4GTT B;  2QNO A;  4MU9 A;  1QSJ A;  1XWQ A;  3DSX B;  1GXO A;  1KSC A;  3PZ3 B;  4GTM B;  1FPP B;  1KZP B;  3QXQ A;  3S4B A;  1H35 A;  2VN4 A;  1RWG A;  4OZV A;  1H3A A;  1WZZ A;  2V3N A;  1C82 A;  1KSD A;  3G6J B;  5GZK A;  4JJJ A;  4RNQ A;  1LXM A;  1D8E B;  2WIN B;  3M7B A;  1FT1 B;  3QXF A;  3M73 A;  1QQF A;  5FO8 B;  1H3C A;  5IL3 A;  3K11 A;  5EAS A;  1FT2 B;  1NC5 A;  4YDE B;  1AYX A;  3GLY A;  2V8K A;  3DSU B;  4Q88 A;  3GT5 A;  2DRS A;  2SQC A;  2YIK A;  3CIH A;  1HM2 A;  2CQT A;  4MBG B;  5ILK A;  3N0F A;  4FXK B;  1QBQ B;  3HXC B;  3KSQ B;  4OZW A;  2V8J A;  1L1Y A;  2RI9 A;  2RI8 A;  3DSW B;  1X1I A;  3M7E A;  3RSY A;  3QT9 A;  1N7Q A;  1N1Z A;  1RW9 A;  2WCO A;  4WU0 A;  1NXC A;  1QAZ A;  1TF4 A;  1WU5 A;  4ZRP A;  2WY7 A;  1H36 A;  2I07 B;  1DOG A;  1S63 B;  5IL8 A;  3DPY B;  5IK0 A;  2VN7 A;  1H54 A;  1O1R B;  1LTX B;  5JMF A;  1X1H A;  1N24 A;  4QT9 A;  3ACS A;  3Q73 B;  3W7S A;  4TF4 A;  5JPM B;  1N7P A;  4GL3 A;  3M72 A;  1R76 A;  3HXF B;  1D8D B;  5IK6 A;  1C3D A;  2H6F B;  2EAD A;  3E30 B;  1XW2 A;  3DSS B;  2BB5 A;  3WIR A;  1TN7 B;  4OK2 A;  3WKF A;  1HXA A;  2WY8 A;  1WU4 A;  3QFZ A;  4EHM B;  1FP3 A;  2XQW A;  1WU6 A;  3S4C A;  4NEI A;  1FAE A;  3HXB B;  3E32 B;  5E2J A;  1W3Y A;  1TNY B;  3QFY A;  5M7Y A;  3QG0 A;  3VXD A;  2FV1 A;  5EAT A;  5DHI A;  4GTO B;  1GXN A;  3QDE A;  3PYA A;  2GH4 A;  1RQ5 A;  4KTP A;  4AYP A;  1N4Q B;  1KZO B;  1LF9 A;  4L6X A;  1OJP A;  3SDR A;  1TNU B;  1H39 A;  3T33 A;  4AYO A;  1IA6 A;  2XWJ B;  3AFL A;  1L2A A;  1UT9 A;  4DOD A;  2BBC A;  1MZC B;  2BB6 A;  1J0N A;  1VD5 A;  1LD7 B;  1H37 A;  2RGK A;  3M76 A;  1G9J A;  5DHK A;  4XUV A;  5JPN B;  3DST B;  4LNB B;  4C1S A;  1LOH A;  1X1J A;  2D8L A;  1OJN A;  2Z07 A;  3D5S A;  3DRA B;  3K7X A;  3G4F A;  5IKA A;  5GY3 A;  3PZ2 B;  1SQC A;  3WKH A;  3A0O A;  4GTR B;  3OED A;  2FUT A;  1N4P B;  4D4D A;  5FO9 B;  3M75 A;  2V3P A;  3SDV A;  5ILD A;  1KS8 A;  1G6I A;  2H6G B;  4WVA A;  4Q2B A;  3A3V A;  4FNV A;  1HZF A;  4ZH5 A;  1HV6 A;  5GW7 A;  1F1S A;  2F6D A;  2XFG A;  4CJ0 A;  3CU7 A;  1FBW A;  3E33 B;  1FO2 A;  1G9G A;  3HXE B;  1G87 A;  2Q1F A;  3RX8 A;  1F9D A;  1N95 B;  1N23 A;  5IM1 A;  1LD8 B;  1ULV A;  2B4F A;  3P5P A;  3SFY B;  4OK4 A;  2ZIR B;  3H3K A;  1N4S B;  1HN0 A;  1KRF A;  3H7L A;  2WYN A;  1RWA A;  2E22 A;  1JS4 A;  3PZ4 B;  3NFV A;  4MMI A;  1GSZ A;  4V1S A;  3TF4 A;  3W7T A;  2B39 A;  3VSM A;  4FJQ A;  4Z4L A;  2NOJ A;  5EAU A;  3EU5 B;  2FV0 A;  3D5R A;  4EL8 A;  1LF6 A;  2DRQ A;  3DSV B;  1HM3 A;  2PMV A;  1I8Q A;  2D5J A;  3ANJ A;  2ZZR A;  2JG0 A;  1JCQ B;  2G02 A;  4ONT A;  1F9G A;  3X17 A;  1RWF A;  2FUQ A;  2NVP A;  3ANI A;  1NL4 B;  3H2W A;  1H3B A;  2A73 B;  2G0D A;  5CZL A;  1JCS B;  3RRS A;  5CD2 A;  4L0G A;  3Q78 B;  3Q7F B;  1H14 A;  2ZBL A;  3SDQ A;  1GXM A;  3WIQ A;  3PMM A;  3D3I A;  1O5M B;  1GAH A;  1TNZ B;  3QPF A;  5ILJ A;  1HCU A;  1N21 A;  3M7L A;  3NNB A;  4YCR A;  3Q7A B;  3WC3 A;  3RJ3 A;  1K72 A;  2EAC A;  3E37 B;  1N9A B;  5IK9 A;  5CA3 A;  3W7X A;  1OJO A;  1N7N A;  1O1T B;  4Z4J A;  3PYB A;  4FUS A;  5DGQ A;  3E80 A;  3QRY A;  2E24 A;  1F9O A;  4YDO B;  3HXD B;  2CQS A;  3P2C A;  1W6K A;  2FBA A;  3W5M A;  1O6R A;  1O1S B;  3ANK A;  1TN8 B;  1IS9 A;  4GTQ B;  3S4A A;  2AHG A;  3W7U A;  5FOB B;  1N20 A;  1HMU A;  2H6H B;  1HXC A;  3E34 B;  4GTV B;  2ONH A;  4D4B A;  1GA2 A;  1N1B A;  3QT3 A;  2EAE A;  1H13 A;  4J5T A;  1DL2 A;  1KWF A;  4GAX A;  2BRW A;  3Q79 B;  4GTS B;  4F10 A;  4V1R A;  3SDU A;  2XWB B;  3M00 A;  4DOE A;  3P5R A;  2GZ6 A;  4E1Y A;  3LZ9 A;  1V7V A;  3M02 A;  2WII B;  1CB8 A;  1EGU A;  1TNB B;  3EQA A;  4KKI A;  1V5D A;  4M76 A;  2IEJ B;  3M74 A;  1N4R B;  3EU8 A;  1FMI A;  1N7O A;  1S64 B;  3M78 A;  5IKH A;  1TN6 B;  2X03 A;  3VSN A;  3ON6 A;  3WUX A;  4F13 A;  1HX9 A;  2R2L B;  3KQ4 A;  3E6U A;  2EAB A;  1V5C A;  1O79 A;  5KKB A;  4ZG8 A;  2JF4 A;  1KKT A;  4AYQ A;  3GZK A;  1KFG A;  1O6H A;  2ZIS B;  4LNV A;  5ILI A;  3RX7 A;  1GHQ A;  4KKJ A;  3QSP A;  4BOK A;  4LNG B;  4LIX A;  3M01 A;  2F0Y B;  3WKI A;  4WVC A;  5AGD A;  5C05 A;  1N22 A;  1OJM A;  1RWC A;  3E73 A;  1TNO B;  3AFJ A;  3KLS A;  5JMD A;  4CJ1 A;  5M7I A;  2AHF A;  4MMH A;  2OKX A;  3QWT A;  4FXG B;  5ILH A;  3OXU A;  3G4D A;  2AFA A;  2J5C A;  3WIW A;  5MEH A;  4D94 A;  3RX5 A;  4BOJ A;  3SAE A;  1X81 B; 
#chains in the Genus database with same CATH homology
 1N94 B;  1NI1 B;  3PZ1 B;  1JCR B;  1DCE B;  3WKG A;  4GTP B;  3REN A;  1W6J A;  2GOX A;  4ZH1 A;  1GLM A;  4ZRQ A;  3ACT A;  1UG9 A;  2H6I B;  1V7X A;  1H12 A;  4L9P B;  3KSL B;  2FUZ A;  2A8Z A;  1KRE A;  3M77 A;  1IA7 A;  5DGR A;  1V7W A;  1AGM A;  3C72 B;  1FBO A;  2PN5 A;  3Q75 B;  3W5N A;  2P0V A;  3M7C A;  3S9V A;  5FO7 B;  3SDT A;  4D4A A;  2V8I A;  1SA5 B;  1UMP A;  3EZ8 A;  4KTR A;  2BED B;  3M71 A;  1CLC A;  1X9D A;  3W7W A;  3S4D A;  1O6Q A;  3SQC A;  1XWT A;  4TXT A;  4D4C A;  1FCE A;  3VW5 A;  1FO3 A;  2DRO A;  3EUV B;  1GAI A;  4WVB A;  1CEM A;  4CE7 A;  3SFX B;  1SA4 B;  4AYR A;  2DRR A;  2JJB A;  4GTT B;  2QNO A;  4MU9 A;  1QSJ A;  1XWQ A;  3DSX B;  1GXO A;  1KSC A;  3PZ3 B;  4GTM B;  1FPP B;  1KZP B;  3QXQ A;  3S4B A;  1H35 A;  2VN4 A;  1H3A A;  1WZZ A;  2V3N A;  1KSD A;  3G6J B;  5GZK A;  4JJJ A;  1D8E B;  2WIN B;  3M7B A;  1FT1 B;  3QXF A;  3M73 A;  1QQF A;  5FO8 B;  1H3C A;  3K11 A;  1FT2 B;  1NC5 A;  4YDE B;  1AYX A;  3GLY A;  2V8K A;  3DSU B;  4Q88 A;  3GT5 A;  2DRS A;  2SQC A;  2YIK A;  3CIH A;  2CQT A;  4MBG B;  4FXK B;  1QBQ B;  3HXC B;  3KSQ B;  2V8J A;  1L1Y A;  2RI9 A;  2RI8 A;  3DSW B;  3M7E A;  3RSY A;  3QT9 A;  4WU0 A;  1NXC A;  1WU5 A;  1TF4 A;  4ZRP A;  2WY7 A;  1H36 A;  2I07 B;  1DOG A;  1S63 B;  3DPY B;  2VN7 A;  1H54 A;  1O1R B;  1LTX B;  4QT9 A;  3ACS A;  3Q73 B;  3W7S A;  4TF4 A;  5JPM B;  4GL3 A;  3M72 A;  1R76 A;  3HXF B;  1D8D B;  1C3D A;  2H6F B;  2EAD A;  3E30 B;  1XW2 A;  3DSS B;  2BB5 A;  3WIR A;  1TN7 B;  3WKF A;  2WY8 A;  1WU4 A;  3QFZ A;  4EHM B;  1FP3 A;  2XQW A;  1WU6 A;  3S4C A;  1FAE A;  3HXB B;  3E32 B;  5E2J A;  1TNY B;  3QFY A;  5M7Y A;  3QG0 A;  3VXD A;  2FV1 A;  4GTO B;  1GXN A;  3QDE A;  3PYA A;  2GH4 A;  1RQ5 A;  4KTP A;  4AYP A;  1N4Q B;  1KZO B;  1LF9 A;  4L6X A;  3SDR A;  1TNU B;  1H39 A;  3T33 A;  4AYO A;  1IA6 A;  2XWJ B;  1L2A A;  1UT9 A;  4DOD A;  2BBC A;  1MZC B;  2BB6 A;  1VD5 A;  1LD7 B;  1H37 A;  2RGK A;  3M76 A;  1G9J A;  4XUV A;  5JPN B;  3DST B;  4LNB B;  4C1S A;  2D8L A;  2Z07 A;  3D5S A;  3DRA B;  3K7X A;  5GY3 A;  3PZ2 B;  1SQC A;  3WKH A;  4GTR B;  3OED A;  1N4P B;  4D4D A;  5FO9 B;  3M75 A;  2V3P A;  3SDV A;  1KS8 A;  1G6I A;  2H6G B;  4WVA A;  4Q2B A;  3A3V A;  1HZF A;  4ZH5 A;  5GW7 A;  2XFG A;  2F6D A;  4CJ0 A;  3CU7 A;  1FBW A;  3E33 B;  1FO2 A;  1G9G A;  3HXE B;  1G87 A;  3RX8 A;  1F9D A;  1N95 B;  1LD8 B;  1ULV A;  2B4F A;  3P5P A;  3SFY B;  2ZIR B;  3H3K A;  1N4S B;  1KRF A;  3H7L A;  2WYN A;  1JS4 A;  3PZ4 B;  1GSZ A;  4V1S A;  3TF4 A;  3W7T A;  2B39 A;  4Z4L A;  2NOJ A;  3EU5 B;  2FV0 A;  3D5R A;  4EL8 A;  1LF6 A;  2DRQ A;  3DSV B;  2PMV A;  2D5J A;  3ANJ A;  2ZZR A;  2JG0 A;  1JCQ B;  2G02 A;  4ONT A;  3X17 A;  2NVP A;  3ANI A;  1NL4 B;  3H2W A;  1H3B A;  2A73 B;  2G0D A;  5CZL A;  1JCS B;  3RRS A;  5CD2 A;  4L0G A;  3Q78 B;  3Q7F B;  1H14 A;  2ZBL A;  3SDQ A;  1GXM A;  3WIQ A;  3PMM A;  3D3I A;  1O5M B;  1GAH A;  1TNZ B;  3QPF A;  1HCU A;  3M7L A;  4YCR A;  3Q7A B;  3WC3 A;  3RJ3 A;  1K72 A;  2EAC A;  3E37 B;  1N9A B;  5CA3 A;  3W7X A;  1O1T B;  4Z4J A;  3PYB A;  4FUS A;  5DGQ A;  3QRY A;  1F9O A;  4YDO B;  3HXD B;  2CQS A;  3P2C A;  1W6K A;  2FBA A;  3W5M A;  1O6R A;  1O1S B;  3ANK A;  1TN8 B;  1IS9 A;  4GTQ B;  3S4A A;  2AHG A;  3W7U A;  5FOB B;  2H6H B;  3E34 B;  4GTV B;  4D4B A;  1GA2 A;  3QT3 A;  2EAE A;  1H13 A;  4J5T A;  1DL2 A;  1KWF A;  3Q79 B;  4GTS B;  4V1R A;  3SDU A;  2XWB B;  4DOE A;  3P5R A;  2GZ6 A;  1V7V A;  2WII B;  1TNB B;  3EQA A;  4KKI A;  1V5D A;  4M76 A;  2IEJ B;  3M74 A;  1N4R B;  3EU8 A;  1FMI A;  1S64 B;  3M78 A;  1TN6 B;  3ON6 A;  3WUX A;  3KQ4 A;  2R2L B;  3E6U A;  2EAB A;  1V5C A;  1O79 A;  5KKB A;  4ZG8 A;  2JF4 A;  1KKT A;  4AYQ A;  3GZK A;  1KFG A;  1O6H A;  2ZIS B;  4LNV A;  3RX7 A;  1GHQ A;  4KKJ A;  3QSP A;  4BOK A;  4LNG B;  4LIX A;  2F0Y B;  3WKI A;  4WVC A;  5AGD A;  3E73 A;  1TNO B;  3AFJ A;  3KLS A;  4CJ1 A;  5M7I A;  2AHF A;  2OKX A;  3QWT A;  4FXG B;  3OXU A;  2AFA A;  3WIW A;  5MEH A;  4D94 A;  3RX5 A;  4BOJ A;  3SAE A;  1X81 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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