1JCRB

Crystal structure of rat protein farnesyltransferase complexed with the non-substrate tetrapeptide inhibitor cvfm and farnesyl diphosphate substrate
Total Genus 154
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
sequence length
407
structure length
407
Chain Sequence
PVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PROTEIN FARNESYLTRANSFERASE, ALPHA SUBUNIT
publication title The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Transferase/transferase inhibitor
total genus 154
structure length 407
sequence length 407
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2001-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1jcrB00
3KLSA 3Q78B 2B39A 2ZISB 1GSZA 3E34B 4MBGB 1N9AB 1LD8B 1N4RB 1S63B 4FXGB 4BOKA 4YDEB 2PMVA 2H6FB 1H3CA 1N4SB 1TNOB 3CU7A 1QQFA 1O5MB 4FXKB 4GTOB 1LD7B 2BBCA 1H39A 3Q75B 1FT2B 5FO8B 2XWJB 3PZ1B 1O6RA 3DSSB 1NI1B 3PZ2B 4GTQB 1SQCA 2PN5A 4LNVA 1O6QA 4GTSB 4L9PB 1D8EB 4KKIA 3C72B 4LNGB 4D4DA 3K7XA 3DSTB 3KSLB 4KKJA 4D4AA 1N4PB 1QBQB 4C1SA 1SA4B 1S64B 3DSVB 1H3AA 3DPYB 4LNBB 2V8IA 3DSXB 3SFXB 2WINB 1TNBB 2XWBB 1GXNA 3HXBB 3D5RA 4BOJA 1FT1B 2G02A 3Q7FB 1C3DA 1KZPB 2XQWA 3D5SA 1X81B 4GTTB 3E30B 4ZRQA 3E33B 5FO9B 2BEDB 1O1TB 3DRAB 1H37A 1TN7B 2H6GB 2A73B 1O1RB 4D94A 2WY7A 1W6KA 3Q79B 1H35A 1QSJA 3Q7AB 5JPNB 1HZFA 4EHMB 3Q73B 4ONTA 5FOBB 1O79A 1JCRB 3OEDA 4GTMB 3PZ3B 4ZRPA 1TN8B 3DSWB 2V3PA 3E37B 4MU9A 2BB5A 1H3BA 1LTXB 2G0DA 2IEJB 3E32B 2F0YB 1TNYB 4M76A 1TN6B 2H6IB 1KZOB 4GTPB 5FO7B 1N4QB 2ZIRB 4D4CA 1W6JA 1GXOA 4GTRB 4ZH1A 4V1RA 1FPPB 2SQCA 3HXDB 1UMPA 1D8DB 1NL4B 1O6HA 3EU5B 2V8KA 4YDOB 5AGDA 2V3NA 3SFYB 3SQCA 3G6JB 2V8JA 1TNUB 3KSQB 2WIIB 1JCSB 1N95B 1DCEB 1O1SB 3OXUA 3PZ4B 1SA5B 1GHQA 3HXCB 4V1SA 1N94B 2R2LB 1JCQB 2H6HB 3HXEB 1TNZB 3EUVB 2WY8A 3RJ3A 5JPMB 4D4BA 2GOXA 3HXFB 3KQ4A 1MZCB 3DSUB 2I07B 2NOJA 1R76A 1GXMA 2BB6A 4GTVB 1H36A
chains in the Genus database with same CATH superfamily
1H54A 1FCEA 2AHGA 3Q78B 4RNQA 1V7WA 5KKBA 3E34B 4MBGB 2VN7A 1S63B 3QFZA 1OJPA 4FXGB 4YDEB 1IS9A 1O5MB 4LIXA 2X03A 4GTOB 1LD7B 3QXFA 2BBCA 5ILYA 1HM3A 2A8ZA 4GAXA 1O6RA 3DSSB 5GW7A 1G6IA 3E73A 1L1YA 1HXCA 1F9OA 4KKIA 3P5RA 1N7QA 4TXTA 5JMDA 5EAUA 5CD2A 4OZVA 1LF9A 1N1ZA 3S4DA 1SA4B 1X9DA 5ILHA 2FUZA 3QDEA 5IK6A 3X17A 1OJNA 3WKHA 1RQ5A 3D3IA 2XWBB 3D5RA 3QT3A 3N0FA 1GAHA 2WYNA 1C82A 1RWHA 4DODA 1C3DA 3T33A 1KZPB 3W7XA 1KFGA 5DHIA 3D5SA 4GTTB 1X1JA 1N22A 1G87A 1WU5A 4F10A 3W7SA 1QSJA 3Q7AB 3S4AA 3QXQA 5DGRA 3M72A 4CJ0A 1TF4A 3W7UA 4ZRPA 1TN8B 4MU9A 2BB5A 3WC3A 3GZKA 4M76A 1TN6B 2H6IB 1KZOB 4GTPB 1N4QB 2ONHA 3E7JA 4ZH1A 1NC5A 1FPPB 1FAEA 3ON6A 2FBAA 4L6XA 1UMPA 3M7BA 2F6DA 1IA6A 1N7NA 1CEMA 2ZZRA 2V8KA 5ILJA 1NXCA 3G6JB 2BRWA 1LXMA 1JCSB 4OK4A 3S9VA 3K11A 3M73A 3EZ8A 3PZ4B 1GHQA 2RGKA 3QRYA 4NEIA 4V1SA 5M7IA 1RWAA 5ILZA 1V7VA 1V7XA 1HMWA 3PYAA 2NOJA 1R76A 5IK9A 1H14A 4GTVB 3SAEA 2B39A 1W3YA 2EADA 1FMIA 4BOKA 1H3CA 1N4SB 1HMUA 1TNOB 1QQFA 3QT9A 5GZKA 3VW5A 3SDTA 1H39A 3Q75B 4OK2A 1DOGA 5GY3A 1NI1B 2BRPA 1RWGA 3H7LA 4L9PB 4D4DA 1KSCA 3AFJA 4L0GA 4KKJA 1XWQA 3E6UA 3DSVB 1S64B 5EASA 2D5JA 4Q88A 3DPYB 5CZLA 4DOEA 3A3VA 1WU6A 2P0VA 2WINB 3HXBB 5C05A 4Z4LA 2G02A 2J5CA 2GH4A 1KSDA 1HXAA 3S4CA 3A0OA 2WCOA 1GAIA 3M7LA 1X81B 3RX5A 2BRVX 4EL8A 2H6GB 1F1SA 3H2WA 3M7EA 1O1RB 1W6KA 2GZ6A 3WIRA 3RRSA 4J5TA 1HZFA 1N24A 2FV0A 1FBOA 4EHMB 1HCUA 1O79A 3PYBA 3ANKA 1JCRB 3OEDA 3PMMA 1I8QA 2DRRA 2RI8A 4ZG8A 3E37B 3GLYA 1K72A 2OKXA 2G0DA 3E32B 3NFVA 4AYOA 4OJZA 1AYXA 1W6JA 4FUSA 5IKHA 4GTRB 3NNBA 1VD5A 4TF4A 1D8DB 1O6HA 4CJ1A 3EU5B 1FO3A 4YDOB 3SFYB 1GA2A 3N0GA 4JJJA 1TNUB 1RW9A 2WIIB 3M71A 2E24A 1N94B 2CQSA 5CA3A 2WY8A 1HV6A 3HXFB 3KQ4A 1MZCB 3ANJA 1N7PA 3DSUB 2I07B 1GXMA 2BB6A 1LOHA 3KLSA 4AYQA 4DI5A 3M01A 1LD8B 4AYPA 2PMVA 2H6FB 4FXKB 3CU7A 1OJOA 5M7YA 3WIQA 1FT2B 5FO8B 2XWJB 1UT9A 1H13A 1N21A 3VXDA 3M76A 3PZ2B 3AFLA 3M00A 1O6QA 1D8EB 3C72B 3K7XA 3GT5A 3KSLB 4D4AA 3SDVA 4MMHA 4C1SA 5JMFA 1KS8A 3P5PA 1H3AA 1HX9A 3E80A 3M7CA 3W7WA 3RSYA 1HM2A 5IM1A 2CQTA 2VN4A 3WKGA 3DSXB 2AHFA 1TNBB 1GXNA 2EACA 3M74A 1FO2A 1FT1B 1XW2A 3Q7FB 2Z07A 3M77A 1KWFA 1N20A 2ONGA 3S4BA 2E22A 1N23A 3E33B 1IA7A 3DRAB 1H37A 1TN7B 1UG9A 2A73B 3RX7A 4FNVA 2AFAA 2EAEA 4D94A 3Q79B 3SDQA 1H35A 5JPNB 3Q73B 5FOBB 1F9GA 1F9DA 4YCRA 4GTMB 3G4FA 5DHKA 3PZ3B 2YIKA 1KRFA 4WVBA 4KTPA 1TNYB 2FUTA 1V5DA 2ZIRB 4D4CA 3VSMA 3W5MA 4XUVA 1GXOA 2DRSA 1FBWA 2B4FA 4V1RA 2SQCA 3HXDB 1G9GA 1V5CA 3VSNA 5AGDA 1N1BA 2RI9A 2V3NA 4WVAA 5IKAA 2V8JA 2JG0A 1RWFA 1WU4A 1N95B 1DL2A 1RWCA 3G4DA 1DCEB 1O1SB 3WKIA 3OXUA 4KTRA 1SA5B 3HXCB 4QT9A 3QWTA 3W5NA 2R2LB 1JCQB 1TNZB 3EUVB 3M02A 2NVPA 3RJ3A 2JF4A 4D4BA 1WZZA 3QPFA 1N7RA 1J0NA 1HXGA 4MMIA 1J0MA 3QFYA 5ILDA 3M75A 2ZISB 1GSZA 1GLMA 1LXKA 3QSPA 1N9AB 1N4RB 4Q2BA 3QG0A 4WU0A 5ILKA 5ILIA 3PZ1B 1L2AA 3WUXA 3EQAA 4GTQB 1SQCA 2PN5A 4LNVA 1HN0A 4GL3A 4GTSB 1KREA 4LNGB 3WKFA 5EATA 3DSTB 1FP3A 1QAZA 1N4PB 1QBQB 3P2CA 3EU8A 3ANIA 2WDAA 1OJMA 1LF6A 4LNBB 2V8IA 3SFXB 3RX8A 4BOJA 2DRQA 3ACSA 4ZH5A 3WIWA 1X1IA 2XQWA 1XWTA 3SDUA 3E30B 3M78A 4ZRQA 5FO9B 2BEDB 1O1TB 1JS4A 3SDRA 2QNOA 2WY7A 4E1YA 1AGMA 4ONTA 2FUQA 5IL3A 3DSWB 2V3PA 5MEHA 2Q1FA 1KKTA 1H3BA 1LTXB 2IEJB 3TF4A 1EGUA 2F0YB 4OZWA 3LZ9A 5IK0A 3H3KA 4WVCA 2JJBA 5FO7B 1G9JA 4CE7A 3ACTA 2XFGA 5DGQA 1NL4B 1X1HA 4FJQA 3RENA 5E2JA 3SQCA 1CLCA 3KSQB 2ZBLA 2DROA 2EABA 1CB8A 2D8LA 1ULVA 2H6HB 3HXEB 5JPMB 4AYRA 1H12A 2GOXA 2FV1A 4F13A 5IL8A 1N7OA 4Z4JA 3W7TA 3CIHA 1H36A
chains in the Genus database with same CATH topology
1H54A 1FCEA 2AHGA 3Q78B 1V7WA 5KKBA 3E34B 4MBGB 2VN7A 1S63B 3QFZA 4FXGB 4YDEB 1IS9A 1O5MB 4LIXA 4GTOB 1LD7B 3QXFA 2BBCA 2A8ZA 1O6RA 3DSSB 5GW7A 1G6IA 3E73A 1L1YA 1F9OA 4KKIA 3P5RA 4TXTA 5CD2A 1LF9A 3S4DA 1SA4B 1X9DA 2FUZA 3QDEA 3X17A 3WKHA 1RQ5A 3D3IA 2XWBB 3D5RA 3QT3A 1GAHA 2WYNA 4DODA 1C3DA 3T33A 1KZPB 3W7XA 1KFGA 3D5SA 4GTTB 1G87A 1WU5A 3W7SA 1QSJA 3Q7AB 3S4AA 3QXQA 5DGRA 3M72A 4CJ0A 1TF4A 3W7UA 4ZRPA 1TN8B 4MU9A 2BB5A 3WC3A 3GZKA 4M76A 1TN6B 2H6IB 1KZOB 4GTPB 1N4QB 4ZH1A 1NC5A 1FPPB 1FAEA 3ON6A 2FBAA 4L6XA 1UMPA 3M7BA 2F6DA 1IA6A 2ZZRA 1CEMA 2V8KA 1NXCA 3G6JB 1JCSB 3S9VA 3K11A 3M73A 3EZ8A 3PZ4B 1GHQA 2RGKA 3QRYA 5M7IA 4V1SA 1V7VA 1V7XA 3PYAA 2NOJA 1R76A 1H14A 4GTVB 3SAEA 2B39A 2EADA 1FMIA 4BOKA 1H3CA 1N4SB 1TNOB 1QQFA 3QT9A 5GZKA 3VW5A 3SDTA 1H39A 3Q75B 1DOGA 5GY3A 1NI1B 3H7LA 4L9PB 4D4DA 1KSCA 3AFJA 4L0GA 4KKJA 1XWQA 3E6UA 3DSVB 1S64B 2D5JA 4Q88A 3DPYB 5CZLA 4DOEA 3A3VA 1WU6A 2P0VA 2WINB 3HXBB 4Z4LA 2G02A 2GH4A 1KSDA 3S4CA 1GAIA 3M7LA 1X81B 3RX5A 4EL8A 2H6GB 3H2WA 3M7EA 1O1RB 1W6KA 2GZ6A 3WIRA 3RRSA 4J5TA 1HZFA 2FV0A 1FBOA 4EHMB 1HCUA 1O79A 3PYBA 3ANKA 1JCRB 3OEDA 3PMMA 2DRRA 2RI8A 4ZG8A 3E37B 3GLYA 1K72A 2OKXA 2G0DA 3E32B 4AYOA 1AYXA 1W6JA 4FUSA 4GTRB 1VD5A 4TF4A 1D8DB 1O6HA 4CJ1A 3EU5B 1FO3A 4YDOB 3SFYB 1GA2A 4JJJA 1TNUB 2WIIB 3M71A 1N94B 2CQSA 5CA3A 2WY8A 3HXFB 3KQ4A 1MZCB 3ANJA 3DSUB 2I07B 1GXMA 2BB6A 3KLSA 4AYQA 1LD8B 4AYPA 2PMVA 2H6FB 4FXKB 3CU7A 5M7YA 3WIQA 1FT2B 5FO8B 2XWJB 1UT9A 1H13A 3VXDA 3M76A 3PZ2B 1O6QA 1D8EB 3C72B 3K7XA 3GT5A 3KSLB 4D4AA 3SDVA 4C1SA 1KS8A 3P5PA 1H3AA 3M7CA 3W7WA 3RSYA 2CQTA 2VN4A 3WKGA 3DSXB 2AHFA 1TNBB 1GXNA 2EACA 3M74A 1FO2A 1FT1B 1XW2A 3Q7FB 2Z07A 3M77A 1KWFA 3S4BA 3E33B 1IA7A 3DRAB 1H37A 1TN7B 1UG9A 2A73B 3RX7A 2AFAA 2EAEA 4D94A 3Q79B 3SDQA 1H35A 5JPNB 3Q73B 5FOBB 1F9DA 4YCRA 4GTMB 3PZ3B 2YIKA 1KRFA 4WVBA 4KTPA 1TNYB 1V5DA 2ZIRB 4D4CA 3W5MA 4XUVA 1GXOA 2DRSA 1FBWA 2B4FA 4V1RA 2SQCA 3HXDB 1G9GA 1V5CA 5AGDA 2RI9A 2V3NA 4WVAA 2V8JA 2JG0A 1WU4A 1N95B 1DL2A 1DCEB 1O1SB 3WKIA 3OXUA 4KTRA 1SA5B 3HXCB 4QT9A 3QWTA 3W5NA 2R2LB 1JCQB 1TNZB 3EUVB 2NVPA 3RJ3A 2JF4A 4D4BA 1WZZA 3QPFA 3QFYA 3M75A 2ZISB 1GSZA 1GLMA 3QSPA 1N9AB 1N4RB 4Q2BA 3QG0A 4WU0A 3PZ1B 1L2AA 3WUXA 3EQAA 4GTQB 1SQCA 2PN5A 4LNVA 4GL3A 4GTSB 1KREA 4LNGB 3WKFA 3DSTB 1FP3A 1N4PB 1QBQB 3P2CA 3EU8A 3ANIA 1LF6A 4LNBB 2V8IA 3SFXB 3RX8A 4BOJA 2DRQA 3ACSA 4ZH5A 3WIWA 2XQWA 1XWTA 3SDUA 3E30B 3M78A 4ZRQA 5FO9B 2BEDB 1O1TB 1JS4A 3SDRA 2QNOA 2WY7A 1AGMA 4ONTA 3DSWB 2V3PA 5MEHA 1KKTA 1H3BA 1LTXB 2IEJB 3TF4A 2F0YB 3H3KA 4WVCA 2JJBA 5FO7B 1G9JA 4CE7A 3ACTA 2XFGA 5DGQA 1NL4B 3RENA 5E2JA 3SQCA 1CLCA 3KSQB 2ZBLA 2DROA 2EABA 2D8LA 1ULVA 2H6HB 3HXEB 5JPMB 4AYRA 1H12A 2GOXA 2FV1A 4Z4JA 3W7TA 3CIHA 1H36A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KLS A;  3Q78 B;  2B39 A;  2ZIS B;  1GSZ A;  3E34 B;  4MBG B;  1N9A B;  1LD8 B;  1N4R B;  1S63 B;  4FXG B;  4BOK A;  4YDE B;  2PMV A;  2H6F B;  1H3C A;  1N4S B;  1TNO B;  3CU7 A;  1QQF A;  1O5M B;  4FXK B;  4GTO B;  1LD7 B;  2BBC A;  1H39 A;  3Q75 B;  1FT2 B;  5FO8 B;  2XWJ B;  3PZ1 B;  1O6R A;  3DSS B;  1NI1 B;  3PZ2 B;  4GTQ B;  1SQC A;  2PN5 A;  4LNV A;  1O6Q A;  4GTS B;  4L9P B;  1D8E B;  4KKI A;  3C72 B;  4LNG B;  4D4D A;  3K7X A;  3DST B;  3KSL B;  4KKJ A;  4D4A A;  1N4P B;  1QBQ B;  4C1S A;  1SA4 B;  1S64 B;  3DSV B;  1H3A A;  3DPY B;  4LNB B;  2V8I A;  3DSX B;  3SFX B;  2WIN B;  1TNB B;  2XWB B;  1GXN A;  3HXB B;  3D5R A;  4BOJ A;  1FT1 B;  2G02 A;  3Q7F B;  1C3D A;  1KZP B;  2XQW A;  3D5S A;  1X81 B;  4GTT B;  3E30 B;  4ZRQ A;  3E33 B;  5FO9 B;  2BED B;  1O1T B;  3DRA B;  1H37 A;  1TN7 B;  2H6G B;  2A73 B;  1O1R B;  4D94 A;  2WY7 A;  1W6K A;  3Q79 B;  1H35 A;  1QSJ A;  3Q7A B;  5JPN B;  1HZF A;  4EHM B;  3Q73 B;  4ONT A;  5FOB B;  1O79 A;  1JCR B;  3OED A;  4GTM B;  3PZ3 B;  4ZRP A;  1TN8 B;  3DSW B;  2V3P A;  3E37 B;  4MU9 A;  2BB5 A;  1H3B A;  1LTX B;  2G0D A;  2IEJ B;  3E32 B;  2F0Y B;  1TNY B;  4M76 A;  1TN6 B;  2H6I B;  1KZO B;  4GTP B;  5FO7 B;  1N4Q B;  2ZIR B;  4D4C A;  1W6J A;  1GXO A;  4GTR B;  4ZH1 A;  4V1R A;  1FPP B;  2SQC A;  3HXD B;  1UMP A;  1D8D B;  1NL4 B;  1O6H A;  3EU5 B;  2V8K A;  4YDO B;  5AGD A;  2V3N A;  3SFY B;  3SQC A;  3G6J B;  2V8J A;  1TNU B;  3KSQ B;  2WII B;  1JCS B;  1N95 B;  1DCE B;  1O1S B;  3OXU A;  3PZ4 B;  1SA5 B;  1GHQ A;  3HXC B;  4V1S A;  1N94 B;  2R2L B;  1JCQ B;  2H6H B;  3HXE B;  1TNZ B;  3EUV B;  2WY8 A;  3RJ3 A;  5JPM B;  4D4B A;  2GOX A;  3HXF B;  3KQ4 A;  1MZC B;  3DSU B;  2I07 B;  2NOJ A;  1R76 A;  1GXM A;  2BB6 A;  4GTV B;  1H36 A; 
#chains in the Genus database with same CATH topology
 1H54 A;  1FCE A;  2AHG A;  3Q78 B;  4RNQ A;  1V7W A;  5KKB A;  3E34 B;  4MBG B;  2VN7 A;  1S63 B;  3QFZ A;  1OJP A;  4FXG B;  4YDE B;  1IS9 A;  1O5M B;  4LIX A;  2X03 A;  4GTO B;  1LD7 B;  3QXF A;  2BBC A;  5ILY A;  1HM3 A;  2A8Z A;  4GAX A;  1O6R A;  3DSS B;  5GW7 A;  1G6I A;  3E73 A;  1L1Y A;  1HXC A;  1F9O A;  4KKI A;  3P5R A;  1N7Q A;  4TXT A;  5JMD A;  5EAU A;  5CD2 A;  4OZV A;  1LF9 A;  1N1Z A;  3S4D A;  1SA4 B;  1X9D A;  5ILH A;  2FUZ A;  3QDE A;  5IK6 A;  3X17 A;  1OJN A;  3WKH A;  1RQ5 A;  3D3I A;  2XWB B;  3D5R A;  3QT3 A;  3N0F A;  1GAH A;  2WYN A;  1C82 A;  1RWH A;  4DOD A;  1C3D A;  3T33 A;  1KZP B;  3W7X A;  1KFG A;  5DHI A;  3D5S A;  4GTT B;  1X1J A;  1N22 A;  1G87 A;  1WU5 A;  4F10 A;  3W7S A;  1QSJ A;  3Q7A B;  3S4A A;  3QXQ A;  5DGR A;  3M72 A;  4CJ0 A;  1TF4 A;  3W7U A;  4ZRP A;  1TN8 B;  4MU9 A;  2BB5 A;  3WC3 A;  3GZK A;  4M76 A;  1TN6 B;  2H6I B;  1KZO B;  4GTP B;  1N4Q B;  2ONH A;  3E7J A;  4ZH1 A;  1NC5 A;  1FPP B;  1FAE A;  3ON6 A;  2FBA A;  4L6X A;  1UMP A;  3M7B A;  2F6D A;  1IA6 A;  1N7N A;  1CEM A;  2ZZR A;  2V8K A;  5ILJ A;  1NXC A;  3G6J B;  2BRW A;  1LXM A;  1JCS B;  4OK4 A;  3S9V A;  3K11 A;  3M73 A;  3EZ8 A;  3PZ4 B;  1GHQ A;  2RGK A;  3QRY A;  4NEI A;  4V1S A;  5M7I A;  1RWA A;  5ILZ A;  1V7V A;  1V7X A;  1HMW A;  3PYA A;  2NOJ A;  1R76 A;  5IK9 A;  1H14 A;  4GTV B;  3SAE A;  2B39 A;  1W3Y A;  2EAD A;  1FMI A;  4BOK A;  1H3C A;  1N4S B;  1HMU A;  1TNO B;  1QQF A;  3QT9 A;  5GZK A;  3VW5 A;  3SDT A;  1H39 A;  3Q75 B;  4OK2 A;  1DOG A;  5GY3 A;  1NI1 B;  2BRP A;  1RWG A;  3H7L A;  4L9P B;  4D4D A;  1KSC A;  3AFJ A;  4L0G A;  4KKJ A;  1XWQ A;  3E6U A;  3DSV B;  1S64 B;  5EAS A;  2D5J A;  4Q88 A;  3DPY B;  5CZL A;  4DOE A;  3A3V A;  1WU6 A;  2P0V A;  2WIN B;  3HXB B;  5C05 A;  4Z4L A;  2G02 A;  2J5C A;  2GH4 A;  1KSD A;  1HXA A;  3S4C A;  3A0O A;  2WCO A;  1GAI A;  3M7L A;  1X81 B;  3RX5 A;  2BRV X;  4EL8 A;  2H6G B;  1F1S A;  3H2W A;  3M7E A;  1O1R B;  1W6K A;  2GZ6 A;  3WIR A;  3RRS A;  4J5T A;  1HZF A;  1N24 A;  2FV0 A;  1FBO A;  4EHM B;  1HCU A;  1O79 A;  3PYB A;  3ANK A;  1JCR B;  3OED A;  3PMM A;  1I8Q A;  2DRR A;  2RI8 A;  4ZG8 A;  3E37 B;  3GLY A;  1K72 A;  2OKX A;  2G0D A;  3E32 B;  3NFV A;  4AYO A;  4OJZ A;  1AYX A;  1W6J A;  4FUS A;  5IKH A;  4GTR B;  3NNB A;  1VD5 A;  4TF4 A;  1D8D B;  1O6H A;  4CJ1 A;  3EU5 B;  1FO3 A;  4YDO B;  3SFY B;  1GA2 A;  3N0G A;  4JJJ A;  1TNU B;  1RW9 A;  2WII B;  3M71 A;  2E24 A;  1N94 B;  2CQS A;  5CA3 A;  2WY8 A;  1HV6 A;  3HXF B;  3KQ4 A;  1MZC B;  3ANJ A;  1N7P A;  3DSU B;  2I07 B;  1GXM A;  2BB6 A;  1LOH A;  3KLS A;  4AYQ A;  4DI5 A;  3M01 A;  1LD8 B;  4AYP A;  2PMV A;  2H6F B;  4FXK B;  3CU7 A;  1OJO A;  5M7Y A;  3WIQ A;  1FT2 B;  5FO8 B;  2XWJ B;  1UT9 A;  1H13 A;  1N21 A;  3VXD A;  3M76 A;  3PZ2 B;  3AFL A;  3M00 A;  1O6Q A;  1D8E B;  3C72 B;  3K7X A;  3GT5 A;  3KSL B;  4D4A A;  3SDV A;  4MMH A;  4C1S A;  5JMF A;  1KS8 A;  3P5P A;  1H3A A;  1HX9 A;  3E80 A;  3M7C A;  3W7W A;  3RSY A;  1HM2 A;  5IM1 A;  2CQT A;  2VN4 A;  3WKG A;  3DSX B;  2AHF A;  1TNB B;  1GXN A;  2EAC A;  3M74 A;  1FO2 A;  1FT1 B;  1XW2 A;  3Q7F B;  2Z07 A;  3M77 A;  1KWF A;  1N20 A;  2ONG A;  3S4B A;  2E22 A;  1N23 A;  3E33 B;  1IA7 A;  3DRA B;  1H37 A;  1TN7 B;  1UG9 A;  2A73 B;  3RX7 A;  4FNV A;  2AFA A;  2EAE A;  4D94 A;  3Q79 B;  3SDQ A;  1H35 A;  5JPN B;  3Q73 B;  5FOB B;  1F9G A;  1F9D A;  4YCR A;  4GTM B;  3G4F A;  5DHK A;  3PZ3 B;  2YIK A;  1KRF A;  4WVB A;  4KTP A;  1TNY B;  2FUT A;  1V5D A;  2ZIR B;  4D4C A;  3VSM A;  3W5M A;  4XUV A;  1GXO A;  2DRS A;  1FBW A;  2B4F A;  4V1R A;  2SQC A;  3HXD B;  1G9G A;  1V5C A;  3VSN A;  5AGD A;  1N1B A;  2RI9 A;  2V3N A;  4WVA A;  5IKA A;  2V8J A;  2JG0 A;  1RWF A;  1WU4 A;  1N95 B;  1DL2 A;  1RWC A;  3G4D A;  1DCE B;  1O1S B;  3WKI A;  3OXU A;  4KTR A;  1SA5 B;  3HXC B;  4QT9 A;  3QWT A;  3W5N A;  2R2L B;  1JCQ B;  1TNZ B;  3EUV B;  3M02 A;  2NVP A;  3RJ3 A;  2JF4 A;  4D4B A;  1WZZ A;  3QPF A;  1N7R A;  1J0N A;  1HXG A;  4MMI A;  1J0M A;  3QFY A;  5ILD A;  3M75 A;  2ZIS B;  1GSZ A;  1GLM A;  1LXK A;  3QSP A;  1N9A B;  1N4R B;  4Q2B A;  3QG0 A;  4WU0 A;  5ILK A;  5ILI A;  3PZ1 B;  1L2A A;  3WUX A;  3EQA A;  4GTQ B;  1SQC A;  2PN5 A;  4LNV A;  1HN0 A;  4GL3 A;  4GTS B;  1KRE A;  4LNG B;  3WKF A;  5EAT A;  3DST B;  1FP3 A;  1QAZ A;  1N4P B;  1QBQ B;  3P2C A;  3EU8 A;  3ANI A;  2WDA A;  1OJM A;  1LF6 A;  4LNB B;  2V8I A;  3SFX B;  3RX8 A;  4BOJ A;  2DRQ A;  3ACS A;  4ZH5 A;  3WIW A;  1X1I A;  2XQW A;  1XWT A;  3SDU A;  3E30 B;  3M78 A;  4ZRQ A;  5FO9 B;  2BED B;  1O1T B;  1JS4 A;  3SDR A;  2QNO A;  2WY7 A;  4E1Y A;  1AGM A;  4ONT A;  2FUQ A;  5IL3 A;  3DSW B;  2V3P A;  5MEH A;  2Q1F A;  1KKT A;  1H3B A;  1LTX B;  2IEJ B;  3TF4 A;  1EGU A;  2F0Y B;  4OZW A;  3LZ9 A;  5IK0 A;  3H3K A;  4WVC A;  2JJB A;  5FO7 B;  1G9J A;  4CE7 A;  3ACT A;  2XFG A;  5DGQ A;  1NL4 B;  1X1H A;  4FJQ A;  3REN A;  5E2J A;  3SQC A;  1CLC A;  3KSQ B;  2ZBL A;  2DRO A;  2EAB A;  1CB8 A;  2D8L A;  1ULV A;  2H6H B;  3HXE B;  5JPM B;  4AYR A;  1H12 A;  2GOX A;  2FV1 A;  4F13 A;  5IL8 A;  1N7O A;  4Z4J A;  3W7T A;  3CIH A;  1H36 A; 
#chains in the Genus database with same CATH homology
 1H54 A;  1FCE A;  2AHG A;  3Q78 B;  1V7W A;  5KKB A;  3E34 B;  4MBG B;  2VN7 A;  1S63 B;  3QFZ A;  4FXG B;  4YDE B;  1IS9 A;  1O5M B;  4LIX A;  4GTO B;  1LD7 B;  3QXF A;  2BBC A;  2A8Z A;  1O6R A;  3DSS B;  5GW7 A;  1G6I A;  3E73 A;  1L1Y A;  1F9O A;  4KKI A;  3P5R A;  4TXT A;  5CD2 A;  1LF9 A;  3S4D A;  1SA4 B;  1X9D A;  2FUZ A;  3QDE A;  3X17 A;  3WKH A;  1RQ5 A;  3D3I A;  2XWB B;  3D5R A;  3QT3 A;  1GAH A;  2WYN A;  4DOD A;  1C3D A;  3T33 A;  1KZP B;  3W7X A;  1KFG A;  3D5S A;  4GTT B;  1G87 A;  1WU5 A;  3W7S A;  1QSJ A;  3Q7A B;  3S4A A;  3QXQ A;  5DGR A;  3M72 A;  4CJ0 A;  1TF4 A;  3W7U A;  4ZRP A;  1TN8 B;  4MU9 A;  2BB5 A;  3WC3 A;  3GZK A;  4M76 A;  1TN6 B;  2H6I B;  1KZO B;  4GTP B;  1N4Q B;  4ZH1 A;  1NC5 A;  1FPP B;  1FAE A;  3ON6 A;  2FBA A;  4L6X A;  1UMP A;  3M7B A;  2F6D A;  1IA6 A;  2ZZR A;  1CEM A;  2V8K A;  1NXC A;  3G6J B;  1JCS B;  3S9V A;  3K11 A;  3M73 A;  3EZ8 A;  3PZ4 B;  1GHQ A;  2RGK A;  3QRY A;  5M7I A;  4V1S A;  1V7V A;  1V7X A;  3PYA A;  2NOJ A;  1R76 A;  1H14 A;  4GTV B;  3SAE A;  2B39 A;  2EAD A;  1FMI A;  4BOK A;  1H3C A;  1N4S B;  1TNO B;  1QQF A;  3QT9 A;  5GZK A;  3VW5 A;  3SDT A;  1H39 A;  3Q75 B;  1DOG A;  5GY3 A;  1NI1 B;  3H7L A;  4L9P B;  4D4D A;  1KSC A;  3AFJ A;  4L0G A;  4KKJ A;  1XWQ A;  3E6U A;  3DSV B;  1S64 B;  2D5J A;  4Q88 A;  3DPY B;  5CZL A;  4DOE A;  3A3V A;  1WU6 A;  2P0V A;  2WIN B;  3HXB B;  4Z4L A;  2G02 A;  2GH4 A;  1KSD A;  3S4C A;  1GAI A;  3M7L A;  1X81 B;  3RX5 A;  4EL8 A;  2H6G B;  3H2W A;  3M7E A;  1O1R B;  1W6K A;  2GZ6 A;  3WIR A;  3RRS A;  4J5T A;  1HZF A;  2FV0 A;  1FBO A;  4EHM B;  1HCU A;  1O79 A;  3PYB A;  3ANK A;  1JCR B;  3OED A;  3PMM A;  2DRR A;  2RI8 A;  4ZG8 A;  3E37 B;  3GLY A;  1K72 A;  2OKX A;  2G0D A;  3E32 B;  4AYO A;  1AYX A;  1W6J A;  4FUS A;  4GTR B;  1VD5 A;  4TF4 A;  1D8D B;  1O6H A;  4CJ1 A;  3EU5 B;  1FO3 A;  4YDO B;  3SFY B;  1GA2 A;  4JJJ A;  1TNU B;  2WII B;  3M71 A;  1N94 B;  2CQS A;  5CA3 A;  2WY8 A;  3HXF B;  3KQ4 A;  1MZC B;  3ANJ A;  3DSU B;  2I07 B;  1GXM A;  2BB6 A;  3KLS A;  4AYQ A;  1LD8 B;  4AYP A;  2PMV A;  2H6F B;  4FXK B;  3CU7 A;  5M7Y A;  3WIQ A;  1FT2 B;  5FO8 B;  2XWJ B;  1UT9 A;  1H13 A;  3VXD A;  3M76 A;  3PZ2 B;  1O6Q A;  1D8E B;  3C72 B;  3K7X A;  3GT5 A;  3KSL B;  4D4A A;  3SDV A;  4C1S A;  1KS8 A;  3P5P A;  1H3A A;  3M7C A;  3W7W A;  3RSY A;  2CQT A;  2VN4 A;  3WKG A;  3DSX B;  2AHF A;  1TNB B;  1GXN A;  2EAC A;  3M74 A;  1FO2 A;  1FT1 B;  1XW2 A;  3Q7F B;  2Z07 A;  3M77 A;  1KWF A;  3S4B A;  3E33 B;  1IA7 A;  3DRA B;  1H37 A;  1TN7 B;  1UG9 A;  2A73 B;  3RX7 A;  2AFA A;  2EAE A;  4D94 A;  3Q79 B;  3SDQ A;  1H35 A;  5JPN B;  3Q73 B;  5FOB B;  1F9D A;  4YCR A;  4GTM B;  3PZ3 B;  2YIK A;  1KRF A;  4WVB A;  4KTP A;  1TNY B;  1V5D A;  2ZIR B;  4D4C A;  3W5M A;  4XUV A;  1GXO A;  2DRS A;  1FBW A;  2B4F A;  4V1R A;  2SQC A;  3HXD B;  1G9G A;  1V5C A;  5AGD A;  2RI9 A;  2V3N A;  4WVA A;  2V8J A;  2JG0 A;  1WU4 A;  1N95 B;  1DL2 A;  1DCE B;  1O1S B;  3WKI A;  3OXU A;  4KTR A;  1SA5 B;  3HXC B;  4QT9 A;  3QWT A;  3W5N A;  2R2L B;  1JCQ B;  1TNZ B;  3EUV B;  2NVP A;  3RJ3 A;  2JF4 A;  4D4B A;  1WZZ A;  3QPF A;  3QFY A;  3M75 A;  2ZIS B;  1GSZ A;  1GLM A;  3QSP A;  1N9A B;  1N4R B;  4Q2B A;  3QG0 A;  4WU0 A;  3PZ1 B;  1L2A A;  3WUX A;  3EQA A;  4GTQ B;  1SQC A;  2PN5 A;  4LNV A;  4GL3 A;  4GTS B;  1KRE A;  4LNG B;  3WKF A;  3DST B;  1FP3 A;  1N4P B;  1QBQ B;  3P2C A;  3EU8 A;  3ANI A;  1LF6 A;  4LNB B;  2V8I A;  3SFX B;  3RX8 A;  4BOJ A;  2DRQ A;  3ACS A;  4ZH5 A;  3WIW A;  2XQW A;  1XWT A;  3SDU A;  3E30 B;  3M78 A;  4ZRQ A;  5FO9 B;  2BED B;  1O1T B;  1JS4 A;  3SDR A;  2QNO A;  2WY7 A;  1AGM A;  4ONT A;  3DSW B;  2V3P A;  5MEH A;  1KKT A;  1H3B A;  1LTX B;  2IEJ B;  3TF4 A;  2F0Y B;  3H3K A;  4WVC A;  2JJB A;  5FO7 B;  1G9J A;  4CE7 A;  3ACT A;  2XFG A;  5DGQ A;  1NL4 B;  3REN A;  5E2J A;  3SQC A;  1CLC A;  3KSQ B;  2ZBL A;  2DRO A;  2EAB A;  2D8L A;  1ULV A;  2H6H B;  3HXE B;  5JPM B;  4AYR A;  1H12 A;  2GOX A;  2FV1 A;  4Z4J A;  3W7T A;  3CIH A;  1H36 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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