1H3CA

Structures of human oxidosqualene cyclase inhibitors bound to an homologous enzyme
Total Genus 235
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
235
sequence length
619
structure length
619
Chain Sequence
AYARTLDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDRDRMEKIRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEEPMQKALRFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSWARATVVALSIVMSRQPVFPLPERARVPELYETDVPPRRRGAKGGGGWIFDALDRALHGYQKLSVHPFRRAAEIRALDWLLERQAGDGSWGGIQPPWFYALIALKILDMTQHPAFIKGWEGLELYGVELDYGGWMFQASISPVWDTGLAVLALRAAGLPADHDRLVKAGEWLLDRQITVPGDWAVKRPNLKPGGFAFQFDNVYYPDVDDTAVVVWALNTLRLPDERRRRDAMTKGFRWIVGMQSSNGGWGAYDVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSFGYDDAWKVIRRAVEYLKREQKPDGSWFGRWGVNYLYGTGAVVSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSYEDPAYAGKGASTPSQTAWALMALIAGGRAESEAARRGVQYLVETQRPDGGWDEPYYTGTGFPGDFYLGYTMYRHVFPTLALGRYKQAI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase
molecule keywords SQUALENE--HOPENE CYCLASE
publication title Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
pubmed doi rcsb
source organism Alicyclobacillus acidocaldarius
total genus 235
structure length 619
sequence length 619
chains with identical sequence B, C
ec nomenclature ec 4.2.1.129: Squalene--hopanol cyclase.
pdb deposition date 2002-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
A PF13243 SQHop_cyclase_C Squalene-hopene cyclase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1h3cA01
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1h3cA02
2ZISB 5FO7B 1D8EB 1O1SB 3DSXB 3PZ3B 3HXEB 1KZOB 1FT1B 1O6HA 3DSWB 4GTTB 4BOJA 2F0YB 1QSJA 3E32B 1SA4B 4M76A 4GTMB 3EUVB 4V1RA 2I07B 3HXDB 4KKJA 4YDOB 2GOXA 2BBCA 3E30B 3DRAB 3HXBB 1GXNA 1N4QB 5JPMB 3K7XA 3C72B 4GTPB 2H6IB 1D8DB 5JPNB 2WY8A 1NI1B 3CU7A 3E33B 2PN5A 3SQCA 1N9AB 2ZIRB 1S63B 4D4DA 2XWJB 1JCSB 1LTXB 4GTOB 2V8KA 4MBGB 1H3AA 3DSUB 5FOBB 2WINB 3Q7AB 3HXFB 3D5SA 1H37A 1N4RB 1TNBB 4BOKA 1W6JA 1JCQB 4GTVB 3HXCB 5FO8B 2IEJB 1TNYB 1W6KA 4LNBB 1SA5B 1LD7B 1MZCB 2XWBB 3DSSB 4FXKB 2WY7A 4GTQB 1DCEB 4D4BA 3E34B 4V1SA 2R2LB 2XQWA 1HZFA 1SQCA 2NOJA 2BB5A 1TNZB 1TNOB 1FPPB 2PMVA 1C3DA 2WIIB 3DSTB 2B39A 4ZH1A 4ZRPA 1TN7B 3KSQB 3SFYB 4D94A 4EHMB 2H6HB 3Q78B 5AGDA 3PZ4B 3D5RA 1LD8B 1N4SB 5FO9B 1R76A 1QBQB 2G02A 3KSLB 3Q73B 1H36A 3OXUA 2BEDB 3PZ1B 1H35A 1O1RB 1UMPA 3Q79B 4ZRQA 3KLSA 4C1SA 1O79A 3SFXB 1S64B 3KQ4A 2H6FB 4LNGB 2V3PA 4D4AA 1GXMA 1TNUB 1O6QA 2V8IA 4ONTA 1H39A 1TN6B 3Q75B 1O5MB 1GHQA 3OEDA 2G0DA 3RJ3A 1JCRB 1O1TB 3DSVB 2SQCA 1QQFA 1O6RA 1GSZA 3EU5B 4GTSB 4FXGB 3G6JB 1N4PB 2H6GB 4YDEB 3PZ2B 1H3BA 1KZPB 4MU9A 1H3CA 3E37B 4KKIA 4D4CA 1N94B 3DPYB 1GXOA 4L9PB 2V3NA 2BB6A 1X81B 3Q7FB 1N95B 1TN8B 4GTRB 2V8JA 1FT2B 1NL4B 2A73B 4LNVA
chains in the Genus database with same CATH superfamily
1D8EB 3DSXB 3HXEB 1FT1B 4GTTB 1OJMA 4OK4A 4BOJA 3E32B 3M01A 4GTMB 2I07B 4F13A 3HXDB 4YDOB 1ULVA 2GOXA 1GXNA 4MMIA 2H6IB 2X03A 1LF6A 1KSDA 3CU7A 3G4DA 4TXTA 1G9JA 1G87A 5M7IA 2BRPA 3S4CA 2EABA 3QG0A 2ZIRB 4D4DA 3VW5A 3WKIA 1LTXB 1N1ZA 3A0OA 4GTOB 4MBGB 4MMHA 1KREA 3SDRA 3S4DA 3Q7AB 5DGRA 3HXFB 1H37A 3W7UA 5E2JA 1H13A 1RWCA 3WKFA 1W6JA 1N21A 4GTVB 1GAHA 5FO8B 4LNBB 3W5NA 1MZCB 3DSSB 5IM1A 3PMMA 2EACA 4KTPA 1OJPA 2AHGA 1HXCA 2XQWA 4KTRA 1HZFA 1SQCA 2PMVA 4EL8A 4ZRPA 3SFYB 1J0MA 4D94A 5KKBA 4DODA 1HXGA 2H6HB 3Q78B 5AGDA 1LD8B 1L2AA 5CD2A 1N4SB 1X1HA 3K11A 3KSLB 2G02A 3P5RA 4GL3A 1N7NA 3P2CA 5EATA 4ZRQA 4CJ0A 4DOEA 3KQ4A 1NXCA 3QDEA 2CQSA 1GXMA 4ONTA 3PYBA 3T33A 2G0DA 3RJ3A 1JCRB 4Q88A 4GAXA 3W5MA 5M7YA 1V7WA 4GTSB 4YDEB 3PZ2B 3W7TA 2FUTA 3RSYA 1X1IA 3E37B 4KKIA 3M75A 3VSMA 5GY3A 1K72A 2DRRA 2RI9A 3DPYB 2E24A 4L9PB 1WU6A 2V3NA 4ZG8A 1X81B 1FT2B 1HX9A 1NL4B 2GZ6A 2YIKA 2A73B 3M72A 3QT9A 1OJOA 1XWQA 1O1SB 5ILZA 1KZOB 1O6HA 2F0YB 3LZ9A 3VXDA 4KKJA 1N7PA 4AYRA 5ILIA 1H54A 3E30B 1N4QB 4WVCA 4GTPB 1D8DB 3E33B 2CQTA 4OK2A 3E73A 4CE7A 1KKTA 3GLYA 3SQCA 3M71A 4J5TA 1QAZA 1S63B 2V8KA 3D3IA 1I8QA 3SAEA 1OJNA 2AHFA 3E7JA 4BOKA 5CA3A 5EAUA 3S9VA 1JCQB 1AGMA 5DGQA 3ANJA 1SA5B 1LD7B 2XWBB 4FXKB 3M77A 4L6XA 1FO3A 3E34B 2FV0A 2R2LB 1KWFA 1HV6A 3M7BA 2BB5A 1FO2A 1FPPB 1TNOB 2FUQA 1FBWA 1C3DA 2XFGA 3DSTB 5ILDA 2B39A 1TN7B 3ANKA 3QWTA 3KSQB 3RENA 4EHMB 2WYNA 3EQAA 1EGUA 2P0VA 3PZ4B 4QT9A 4NEIA 5FO9B 1R76A 4AYQA 3SDQA 2EAEA 1O1RB 4FUSA 3H2WA 3KLSA 1KRFA 1FMIA 2V8IA 1O6QA 5EASA 2ONHA 1H39A 1FBOA 3Q75B 2OKXA 1O5MB 4E1YA 1HM3A 1L1YA 4JJJA 4CJ1A 3TF4A 3RX5A 2SQCA 1C82A 4WVAA 1N4PB 2H6GB 3QSPA 4AYPA 2A8ZA 1G6IA 1HMUA 1N94B 1GXOA 5IK9A 4GTRB 2QNOA 3M7LA 1GA2A 2ONGA 1LOHA 3CIHA 5GW7A 2ZISB 1V5DA 3QXFA 3PZ3B 4OJZA 3GT5A 1JS4A 4M76A 3EUVB 3A3VA 3WKGA 1W3YA 3M02A 3DRAB 1RWAA 2VN4A 3K7XA 3QPFA 3M7EA 3W7SA 5JPNB 2WY8A 1NI1B 3ON6A 4Z4JA 3QRYA 1DOGA 4ZH5A 1N9AB 2RI8A 1RW9A 1H12A 2XWJB 2EADA 1CLCA 3DSUB 3X17A 2WINB 2J5CA 3WIRA 5IK6A 1N7OA 3D5SA 1N4RB 5DHIA 5JMDA 5JMFA 3HXCB 2IEJB 1TNYB 3M7CA 1LF9A 2Q1FA 2BRWA 4GTQB 1N7RA 3RRSA 4D4BA 1CB8A 3M78A 1H14A 3M00A 2NVPA 2NOJA 1TNZB 4LIXA 3SDUA 2WIIB 1G9GA 5DHKA 2JG0A 5IL3A 1N22A 1KS8A 1WU5A 3D5RA 3QXQA 3W7WA 1N24A 2WCOA 3QFZA 1HM2A 1F9OA 1QBQB 3Q73B 1N1BA 1H36A 2RGKA 3OXUA 2BEDB 3E6UA 1N23A 2BRVX 3P5PA 1WZZA 5IK0A 3WUXA 1S64B 1IA7A 3S4AA 4LNGB 4TF4A 5IKAA 2AFAA 4AYOA 2F6DA 3RX8A 5MEHA 4Q2BA 1GHQA 3NFVA 1NC5A 3SDVA 3OEDA 3ACTA 1O1TB 4WVBA 1UG9A 5CZLA 1V5CA 1LXKA 3DSVB 1O6RA 3EU5B 4FXGB 3G6JB 1KZPB 4MU9A 1CEMA 1LXMA 5GZKA 3WIQA 1GAIA 3VSNA 1F1SA 1V7XA 4RNQA 4D4CA 1RWHA 2BB6A 3WC3A 2V8JA 4WU0A 1VD5A 4OZVA 5FO7B 2ZBLA 3DSWB 1QSJA 1AYXA 1SA4B 1KFGA 1KSCA 4V1RA 3QT3A 3M76A 2FV1A 1HCUA 1GLMA 2BBCA 3HXBB 5JPMB 4DI5A 1FAEA 3AFLA 3C72B 3ACSA 4OZWA 3M74A 4YCRA 3RX7A 3N0FA 2PN5A 3ANIA 2FBAA 2JF4A 1IS9A 1TF4A 1JCSB 1H3AA 1X9DA 2Z07A 5FOBB 3SDTA 3N0GA 3W7XA 2DRSA 5ILYA 1F9GA 1TNBB 5IKHA 5ILKA 1XWTA 1FCEA 2E22A 1W6KA 3EU8A 3WKHA 3GZKA 2D5JA 2WY7A 1DCEB 3NNBA 4V1SA 3AFJA 1RWFA 3S4BA 3M73A 4ZH1A 1IA6A 3PYAA 4F10A 2DRQA 2JJBA 1N20A 3PZ1B 1H35A 1UMPA 2ZZRA 3Q79B 3G4FA 1HMWA 3H7LA 4FJQA 4C1SA 1O79A 2WDAA 3SFXB 5ILJA 2H6FB 4L0GA 4XUVA 1F9DA 2V3PA 4D4AA 1TNUB 4Z4LA 1TN6B 2B4FA 1FP3A 2D8LA 1WU4A 1RQ5A 2VN7A 1QQFA 1GSZA 3QFYA 1HN0A 1H3BA 1J0NA 1H3CA 3H3KA 5IL8A 5C05A 1DL2A 2FUZA 4FNVA 3WIWA 3Q7FB 2DROA 1N95B 1TN8B 1V7VA 3EZ8A 1X1JA 2GH4A 1RWGA 1HXAA 1N7QA 1XW2A 4LNVA 5ILHA 1UT9A 3E80A
chains in the Genus database with same CATH topology
1D8EB 3DSXB 3HXEB 1FT1B 4GTTB 4BOJA 3E32B 4GTMB 2I07B 3HXDB 4YDOB 1ULVA 2GOXA 1GXNA 2H6IB 1LF6A 1KSDA 3CU7A 4TXTA 1G9JA 1G87A 5M7IA 3S4CA 2EABA 3QG0A 2ZIRB 4D4DA 3VW5A 3WKIA 1LTXB 4GTOB 4MBGB 1KREA 3SDRA 3S4DA 3Q7AB 5DGRA 3HXFB 1H37A 3W7UA 5E2JA 1H13A 3WKFA 1W6JA 4GTVB 1GAHA 5FO8B 4LNBB 3W5NA 1MZCB 3DSSB 3PMMA 2EACA 4KTPA 2AHGA 2XQWA 4KTRA 1HZFA 1SQCA 2PMVA 4EL8A 4ZRPA 3SFYB 4D94A 5KKBA 4DODA 2H6HB 3Q78B 5AGDA 1LD8B 1L2AA 5CD2A 1N4SB 3K11A 3KSLB 2G02A 3P5RA 4GL3A 3P2CA 4ZRQA 4CJ0A 4DOEA 3KQ4A 1NXCA 3QDEA 2CQSA 1GXMA 4ONTA 3PYBA 3T33A 2G0DA 3RJ3A 1JCRB 4Q88A 3W5MA 5M7YA 1V7WA 4GTSB 4YDEB 3PZ2B 3W7TA 3RSYA 3E37B 4KKIA 3M75A 5GY3A 1K72A 2DRRA 2RI9A 3DPYB 4ZG8A 4L9PB 1WU6A 2V3NA 1X81B 1FT2B 1NL4B 2GZ6A 2YIKA 2A73B 3M72A 3QT9A 1XWQA 1O1SB 1KZOB 1O6HA 2F0YB 3VXDA 4KKJA 4AYRA 1H54A 3E30B 1N4QB 4WVCA 4GTPB 1D8DB 3E33B 2CQTA 3E73A 4CE7A 1KKTA 3GLYA 3SQCA 3M71A 4J5TA 1S63B 2V8KA 3D3IA 3SAEA 2AHFA 4BOKA 5CA3A 3S9VA 1JCQB 1AGMA 5DGQA 3ANJA 1SA5B 1LD7B 2XWBB 4FXKB 3M77A 4L6XA 1FO3A 3E34B 2FV0A 2R2LB 1KWFA 3M7BA 2BB5A 1FO2A 1FPPB 1TNOB 2XFGA 1FBWA 1C3DA 3DSTB 2B39A 1TN7B 3ANKA 3QWTA 3KSQB 3RENA 4EHMB 2WYNA 3EQAA 2P0VA 3PZ4B 4QT9A 5FO9B 1R76A 4AYQA 3SDQA 2EAEA 1O1RB 4FUSA 3H2WA 3KLSA 1KRFA 1FMIA 2V8IA 1O6QA 2OKXA 1H39A 1FBOA 3Q75B 1O5MB 1L1YA 4JJJA 4CJ1A 3TF4A 3RX5A 2SQCA 4WVAA 1N4PB 2H6GB 3QSPA 4AYPA 2A8ZA 1G6IA 1N94B 1GXOA 4GTRB 2QNOA 3M7LA 1GA2A 3CIHA 5GW7A 2ZISB 1V5DA 3QXFA 3PZ3B 3GT5A 1JS4A 4M76A 3EUVB 3A3VA 3WKGA 3DRAB 2VN4A 3K7XA 3QPFA 3M7EA 3W7SA 5JPNB 2WY8A 1NI1B 3ON6A 4Z4JA 3QRYA 1DOGA 4ZH5A 1N9AB 2RI8A 1H12A 2XWJB 2EADA 1CLCA 3DSUB 3X17A 2WINB 3WIRA 3D5SA 1N4RB 3HXCB 2IEJB 1TNYB 3M7CA 1LF9A 4GTQB 3RRSA 4D4BA 3M78A 1H14A 2NVPA 2NOJA 1TNZB 4LIXA 3SDUA 2WIIB 1G9GA 2JG0A 1KS8A 1WU5A 3D5RA 3QXQA 3W7WA 3QFZA 1F9OA 1QBQB 3Q73B 1H36A 2RGKA 3OXUA 2BEDB 3E6UA 3P5PA 1WZZA 3WUXA 1S64B 1IA7A 3S4AA 4LNGB 4TF4A 2AFAA 4AYOA 2F6DA 3RX8A 5MEHA 4Q2BA 1GHQA 1NC5A 3SDVA 3OEDA 3ACTA 1O1TB 4WVBA 1UG9A 5CZLA 1V5CA 3DSVB 1O6RA 3EU5B 4FXGB 3G6JB 1KZPB 4MU9A 1CEMA 5GZKA 3WIQA 1GAIA 1V7XA 4D4CA 2BB6A 3WC3A 2V8JA 4WU0A 1VD5A 5FO7B 2ZBLA 3DSWB 1QSJA 1AYXA 1SA4B 1KFGA 1KSCA 4V1RA 3QT3A 3M76A 2FV1A 1HCUA 1GLMA 2BBCA 3HXBB 5JPMB 1FAEA 3C72B 3ACSA 3M74A 4YCRA 3RX7A 2PN5A 3ANIA 2FBAA 2JF4A 1IS9A 1TF4A 1JCSB 1H3AA 1X9DA 2Z07A 5FOBB 3SDTA 3W7XA 2DRSA 1TNBB 1XWTA 1FCEA 1W6KA 3EU8A 3WKHA 3GZKA 2D5JA 2WY7A 1DCEB 4V1SA 3AFJA 3S4BA 3M73A 4ZH1A 1IA6A 3PYAA 2DRQA 2JJBA 3PZ1B 1H35A 1UMPA 2ZZRA 3Q79B 3H7LA 4C1SA 1O79A 3SFXB 2H6FB 4L0GA 4XUVA 1F9DA 2V3PA 4D4AA 1TNUB 4Z4LA 1TN6B 2B4FA 1FP3A 2D8LA 1WU4A 1RQ5A 2VN7A 1QQFA 1GSZA 3QFYA 1H3BA 1H3CA 3H3KA 1DL2A 2FUZA 3WIWA 3Q7FB 2DROA 1N95B 1TN8B 1V7VA 3EZ8A 2GH4A 1XW2A 4LNVA 1UT9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZIS B;  5FO7 B;  1D8E B;  1O1S B;  3DSX B;  3PZ3 B;  3HXE B;  1KZO B;  1FT1 B;  1O6H A;  3DSW B;  4GTT B;  4BOJ A;  2F0Y B;  1QSJ A;  3E32 B;  1SA4 B;  4M76 A;  4GTM B;  3EUV B;  4V1R A;  2I07 B;  3HXD B;  4KKJ A;  4YDO B;  2GOX A;  2BBC A;  3E30 B;  3DRA B;  3HXB B;  1GXN A;  1N4Q B;  5JPM B;  3K7X A;  3C72 B;  4GTP B;  2H6I B;  1D8D B;  5JPN B;  2WY8 A;  1NI1 B;  3CU7 A;  3E33 B;  2PN5 A;  3SQC A;  1N9A B;  2ZIR B;  1S63 B;  4D4D A;  2XWJ B;  1JCS B;  1LTX B;  4GTO B;  2V8K A;  4MBG B;  1H3A A;  3DSU B;  5FOB B;  2WIN B;  3Q7A B;  3HXF B;  3D5S A;  1H37 A;  1N4R B;  1TNB B;  4BOK A;  1W6J A;  1JCQ B;  4GTV B;  3HXC B;  5FO8 B;  2IEJ B;  1TNY B;  1W6K A;  4LNB B;  1SA5 B;  1LD7 B;  1MZC B;  2XWB B;  3DSS B;  4FXK B;  2WY7 A;  4GTQ B;  1DCE B;  4D4B A;  3E34 B;  4V1S A;  2R2L B;  2XQW A;  1HZF A;  1SQC A;  2NOJ A;  2BB5 A;  1TNZ B;  1TNO B;  1FPP B;  2PMV A;  1C3D A;  2WII B;  3DST B;  2B39 A;  4ZH1 A;  4ZRP A;  1TN7 B;  3KSQ B;  3SFY B;  4D94 A;  4EHM B;  2H6H B;  3Q78 B;  5AGD A;  3PZ4 B;  3D5R A;  1LD8 B;  1N4S B;  5FO9 B;  1R76 A;  1QBQ B;  2G02 A;  3KSL B;  3Q73 B;  1H36 A;  3OXU A;  2BED B;  3PZ1 B;  1H35 A;  1O1R B;  1UMP A;  3Q79 B;  4ZRQ A;  3KLS A;  4C1S A;  1O79 A;  3SFX B;  1S64 B;  3KQ4 A;  2H6F B;  4LNG B;  2V3P A;  4D4A A;  1GXM A;  1TNU B;  1O6Q A;  2V8I A;  4ONT A;  1H39 A;  1TN6 B;  3Q75 B;  1O5M B;  1GHQ A;  3OED A;  2G0D A;  3RJ3 A;  1JCR B;  1O1T B;  3DSV B;  2SQC A;  1QQF A;  1O6R A;  1GSZ A;  3EU5 B;  4GTS B;  4FXG B;  3G6J B;  1N4P B;  2H6G B;  4YDE B;  3PZ2 B;  1H3B A;  1KZP B;  4MU9 A;  1H3C A;  3E37 B;  4KKI A;  4D4C A;  1N94 B;  3DPY B;  1GXO A;  4L9P B;  2V3N A;  2BB6 A;  1X81 B;  3Q7F B;  1N95 B;  1TN8 B;  4GTR B;  2V8J A;  1FT2 B;  1NL4 B;  2A73 B;  4LNV A; 
#chains in the Genus database with same CATH topology
 1D8E B;  3DSX B;  3HXE B;  1FT1 B;  4GTT B;  1OJM A;  4OK4 A;  4BOJ A;  3E32 B;  3M01 A;  4GTM B;  2I07 B;  4F13 A;  3HXD B;  4YDO B;  1ULV A;  2GOX A;  1GXN A;  4MMI A;  2H6I B;  2X03 A;  1LF6 A;  1KSD A;  3CU7 A;  3G4D A;  4TXT A;  1G9J A;  1G87 A;  5M7I A;  2BRP A;  3S4C A;  2EAB A;  3QG0 A;  2ZIR B;  4D4D A;  3VW5 A;  3WKI A;  1LTX B;  1N1Z A;  3A0O A;  4GTO B;  4MBG B;  4MMH A;  1KRE A;  3SDR A;  3S4D A;  3Q7A B;  5DGR A;  3HXF B;  1H37 A;  3W7U A;  5E2J A;  1H13 A;  1RWC A;  3WKF A;  1W6J A;  1N21 A;  4GTV B;  1GAH A;  5FO8 B;  4LNB B;  3W5N A;  1MZC B;  3DSS B;  5IM1 A;  3PMM A;  2EAC A;  4KTP A;  1OJP A;  2AHG A;  1HXC A;  2XQW A;  4KTR A;  1HZF A;  1SQC A;  2PMV A;  4EL8 A;  4ZRP A;  3SFY B;  1J0M A;  4D94 A;  5KKB A;  4DOD A;  1HXG A;  2H6H B;  3Q78 B;  5AGD A;  1LD8 B;  1L2A A;  5CD2 A;  1N4S B;  1X1H A;  3K11 A;  3KSL B;  2G02 A;  3P5R A;  4GL3 A;  1N7N A;  3P2C A;  5EAT A;  4ZRQ A;  4CJ0 A;  4DOE A;  3KQ4 A;  1NXC A;  3QDE A;  2CQS A;  1GXM A;  4ONT A;  3PYB A;  3T33 A;  2G0D A;  3RJ3 A;  1JCR B;  4Q88 A;  4GAX A;  3W5M A;  5M7Y A;  1V7W A;  4GTS B;  4YDE B;  3PZ2 B;  3W7T A;  2FUT A;  3RSY A;  1X1I A;  3E37 B;  4KKI A;  3M75 A;  3VSM A;  5GY3 A;  1K72 A;  2DRR A;  2RI9 A;  3DPY B;  2E24 A;  4L9P B;  1WU6 A;  2V3N A;  4ZG8 A;  1X81 B;  1FT2 B;  1HX9 A;  1NL4 B;  2GZ6 A;  2YIK A;  2A73 B;  3M72 A;  3QT9 A;  1OJO A;  1XWQ A;  1O1S B;  5ILZ A;  1KZO B;  1O6H A;  2F0Y B;  3LZ9 A;  3VXD A;  4KKJ A;  1N7P A;  4AYR A;  5ILI A;  1H54 A;  3E30 B;  1N4Q B;  4WVC A;  4GTP B;  1D8D B;  3E33 B;  2CQT A;  4OK2 A;  3E73 A;  4CE7 A;  1KKT A;  3GLY A;  3SQC A;  3M71 A;  4J5T A;  1QAZ A;  1S63 B;  2V8K A;  3D3I A;  1I8Q A;  3SAE A;  1OJN A;  2AHF A;  3E7J A;  4BOK A;  5CA3 A;  5EAU A;  3S9V A;  1JCQ B;  1AGM A;  5DGQ A;  3ANJ A;  1SA5 B;  1LD7 B;  2XWB B;  4FXK B;  3M77 A;  4L6X A;  1FO3 A;  3E34 B;  2FV0 A;  2R2L B;  1KWF A;  1HV6 A;  3M7B A;  2BB5 A;  1FO2 A;  1FPP B;  1TNO B;  2FUQ A;  1FBW A;  1C3D A;  2XFG A;  3DST B;  5ILD A;  2B39 A;  1TN7 B;  3ANK A;  3QWT A;  3KSQ B;  3REN A;  4EHM B;  2WYN A;  3EQA A;  1EGU A;  2P0V A;  3PZ4 B;  4QT9 A;  4NEI A;  5FO9 B;  1R76 A;  4AYQ A;  3SDQ A;  2EAE A;  1O1R B;  4FUS A;  3H2W A;  3KLS A;  1KRF A;  1FMI A;  2V8I A;  1O6Q A;  5EAS A;  2ONH A;  1H39 A;  1FBO A;  3Q75 B;  2OKX A;  1O5M B;  4E1Y A;  1HM3 A;  1L1Y A;  4JJJ A;  4CJ1 A;  3TF4 A;  3RX5 A;  2SQC A;  1C82 A;  4WVA A;  1N4P B;  2H6G B;  3QSP A;  4AYP A;  2A8Z A;  1G6I A;  1HMU A;  1N94 B;  1GXO A;  5IK9 A;  4GTR B;  2QNO A;  3M7L A;  1GA2 A;  2ONG A;  1LOH A;  3CIH A;  5GW7 A;  2ZIS B;  1V5D A;  3QXF A;  3PZ3 B;  4OJZ A;  3GT5 A;  1JS4 A;  4M76 A;  3EUV B;  3A3V A;  3WKG A;  1W3Y A;  3M02 A;  3DRA B;  1RWA A;  2VN4 A;  3K7X A;  3QPF A;  3M7E A;  3W7S A;  5JPN B;  2WY8 A;  1NI1 B;  3ON6 A;  4Z4J A;  3QRY A;  1DOG A;  4ZH5 A;  1N9A B;  2RI8 A;  1RW9 A;  1H12 A;  2XWJ B;  2EAD A;  1CLC A;  3DSU B;  3X17 A;  2WIN B;  2J5C A;  3WIR A;  5IK6 A;  1N7O A;  3D5S A;  1N4R B;  5DHI A;  5JMD A;  5JMF A;  3HXC B;  2IEJ B;  1TNY B;  3M7C A;  1LF9 A;  2Q1F A;  2BRW A;  4GTQ B;  1N7R A;  3RRS A;  4D4B A;  1CB8 A;  3M78 A;  1H14 A;  3M00 A;  2NVP A;  2NOJ A;  1TNZ B;  4LIX A;  3SDU A;  2WII B;  1G9G A;  5DHK A;  2JG0 A;  5IL3 A;  1N22 A;  1KS8 A;  1WU5 A;  3D5R A;  3QXQ A;  3W7W A;  1N24 A;  2WCO A;  3QFZ A;  1HM2 A;  1F9O A;  1QBQ B;  3Q73 B;  1N1B A;  1H36 A;  2RGK A;  3OXU A;  2BED B;  3E6U A;  1N23 A;  2BRV X;  3P5P A;  1WZZ A;  5IK0 A;  3WUX A;  1S64 B;  1IA7 A;  3S4A A;  4LNG B;  4TF4 A;  5IKA A;  2AFA A;  4AYO A;  2F6D A;  3RX8 A;  5MEH A;  4Q2B A;  1GHQ A;  3NFV A;  1NC5 A;  3SDV A;  3OED A;  3ACT A;  1O1T B;  4WVB A;  1UG9 A;  5CZL A;  1V5C A;  1LXK A;  3DSV B;  1O6R A;  3EU5 B;  4FXG B;  3G6J B;  1KZP B;  4MU9 A;  1CEM A;  1LXM A;  5GZK A;  3WIQ A;  1GAI A;  3VSN A;  1F1S A;  1V7X A;  4RNQ A;  4D4C A;  1RWH A;  2BB6 A;  3WC3 A;  2V8J A;  4WU0 A;  1VD5 A;  4OZV A;  5FO7 B;  2ZBL A;  3DSW B;  1QSJ A;  1AYX A;  1SA4 B;  1KFG A;  1KSC A;  4V1R A;  3QT3 A;  3M76 A;  2FV1 A;  1HCU A;  1GLM A;  2BBC A;  3HXB B;  5JPM B;  4DI5 A;  1FAE A;  3AFL A;  3C72 B;  3ACS A;  4OZW A;  3M74 A;  4YCR A;  3RX7 A;  3N0F A;  2PN5 A;  3ANI A;  2FBA A;  2JF4 A;  1IS9 A;  1TF4 A;  1JCS B;  1H3A A;  1X9D A;  2Z07 A;  5FOB B;  3SDT A;  3N0G A;  3W7X A;  2DRS A;  5ILY A;  1F9G A;  1TNB B;  5IKH A;  5ILK A;  1XWT A;  1FCE A;  2E22 A;  1W6K A;  3EU8 A;  3WKH A;  3GZK A;  2D5J A;  2WY7 A;  1DCE B;  3NNB A;  4V1S A;  3AFJ A;  1RWF A;  3S4B A;  3M73 A;  4ZH1 A;  1IA6 A;  3PYA A;  4F10 A;  2DRQ A;  2JJB A;  1N20 A;  3PZ1 B;  1H35 A;  1UMP A;  2ZZR A;  3Q79 B;  3G4F A;  1HMW A;  3H7L A;  4FJQ A;  4C1S A;  1O79 A;  2WDA A;  3SFX B;  5ILJ A;  2H6F B;  4L0G A;  4XUV A;  1F9D A;  2V3P A;  4D4A A;  1TNU B;  4Z4L A;  1TN6 B;  2B4F A;  1FP3 A;  2D8L A;  1WU4 A;  1RQ5 A;  2VN7 A;  1QQF A;  1GSZ A;  3QFY A;  1HN0 A;  1H3B A;  1J0N A;  1H3C A;  3H3K A;  5IL8 A;  5C05 A;  1DL2 A;  2FUZ A;  4FNV A;  3WIW A;  3Q7F B;  2DRO A;  1N95 B;  1TN8 B;  1V7V A;  3EZ8 A;  1X1J A;  2GH4 A;  1RWG A;  1HXA A;  1N7Q A;  1XW2 A;  4LNV A;  5ILH A;  1UT9 A;  3E80 A; 
#chains in the Genus database with same CATH homology
 1D8E B;  3DSX B;  3HXE B;  1FT1 B;  4GTT B;  4BOJ A;  3E32 B;  4GTM B;  2I07 B;  3HXD B;  4YDO B;  1ULV A;  2GOX A;  1GXN A;  2H6I B;  1LF6 A;  1KSD A;  3CU7 A;  4TXT A;  1G9J A;  1G87 A;  5M7I A;  3S4C A;  2EAB A;  3QG0 A;  2ZIR B;  4D4D A;  3VW5 A;  3WKI A;  1LTX B;  4GTO B;  4MBG B;  1KRE A;  3SDR A;  3S4D A;  3Q7A B;  5DGR A;  3HXF B;  1H37 A;  3W7U A;  5E2J A;  1H13 A;  3WKF A;  1W6J A;  4GTV B;  1GAH A;  5FO8 B;  4LNB B;  3W5N A;  1MZC B;  3DSS B;  3PMM A;  2EAC A;  4KTP A;  2AHG A;  2XQW A;  4KTR A;  1HZF A;  1SQC A;  2PMV A;  4EL8 A;  4ZRP A;  3SFY B;  4D94 A;  5KKB A;  4DOD A;  2H6H B;  3Q78 B;  5AGD A;  1LD8 B;  1L2A A;  5CD2 A;  1N4S B;  3K11 A;  3KSL B;  2G02 A;  3P5R A;  4GL3 A;  3P2C A;  4ZRQ A;  4CJ0 A;  4DOE A;  3KQ4 A;  1NXC A;  3QDE A;  2CQS A;  1GXM A;  4ONT A;  3PYB A;  3T33 A;  2G0D A;  3RJ3 A;  1JCR B;  4Q88 A;  3W5M A;  5M7Y A;  1V7W A;  4GTS B;  4YDE B;  3PZ2 B;  3W7T A;  3RSY A;  3E37 B;  4KKI A;  3M75 A;  5GY3 A;  1K72 A;  2DRR A;  2RI9 A;  3DPY B;  4ZG8 A;  4L9P B;  1WU6 A;  2V3N A;  1X81 B;  1FT2 B;  1NL4 B;  2GZ6 A;  2YIK A;  2A73 B;  3M72 A;  3QT9 A;  1XWQ A;  1O1S B;  1KZO B;  1O6H A;  2F0Y B;  3VXD A;  4KKJ A;  4AYR A;  1H54 A;  3E30 B;  1N4Q B;  4WVC A;  4GTP B;  1D8D B;  3E33 B;  2CQT A;  3E73 A;  4CE7 A;  1KKT A;  3GLY A;  3SQC A;  3M71 A;  4J5T A;  1S63 B;  2V8K A;  3D3I A;  3SAE A;  2AHF A;  4BOK A;  5CA3 A;  3S9V A;  1JCQ B;  1AGM A;  5DGQ A;  3ANJ A;  1SA5 B;  1LD7 B;  2XWB B;  4FXK B;  3M77 A;  4L6X A;  1FO3 A;  3E34 B;  2FV0 A;  2R2L B;  1KWF A;  3M7B A;  2BB5 A;  1FO2 A;  1FPP B;  1TNO B;  2XFG A;  1FBW A;  1C3D A;  3DST B;  2B39 A;  1TN7 B;  3ANK A;  3QWT A;  3KSQ B;  3REN A;  4EHM B;  2WYN A;  3EQA A;  2P0V A;  3PZ4 B;  4QT9 A;  5FO9 B;  1R76 A;  4AYQ A;  3SDQ A;  2EAE A;  1O1R B;  4FUS A;  3H2W A;  3KLS A;  1KRF A;  1FMI A;  2V8I A;  1O6Q A;  2OKX A;  1H39 A;  1FBO A;  3Q75 B;  1O5M B;  1L1Y A;  4JJJ A;  4CJ1 A;  3TF4 A;  3RX5 A;  2SQC A;  4WVA A;  1N4P B;  2H6G B;  3QSP A;  4AYP A;  2A8Z A;  1G6I A;  1N94 B;  1GXO A;  4GTR B;  2QNO A;  3M7L A;  1GA2 A;  3CIH A;  5GW7 A;  2ZIS B;  1V5D A;  3QXF A;  3PZ3 B;  3GT5 A;  1JS4 A;  4M76 A;  3EUV B;  3A3V A;  3WKG A;  3DRA B;  2VN4 A;  3K7X A;  3QPF A;  3M7E A;  3W7S A;  5JPN B;  2WY8 A;  1NI1 B;  3ON6 A;  4Z4J A;  3QRY A;  1DOG A;  4ZH5 A;  1N9A B;  2RI8 A;  1H12 A;  2XWJ B;  2EAD A;  1CLC A;  3DSU B;  3X17 A;  2WIN B;  3WIR A;  3D5S A;  1N4R B;  3HXC B;  2IEJ B;  1TNY B;  3M7C A;  1LF9 A;  4GTQ B;  3RRS A;  4D4B A;  3M78 A;  1H14 A;  2NVP A;  2NOJ A;  1TNZ B;  4LIX A;  3SDU A;  2WII B;  1G9G A;  2JG0 A;  1KS8 A;  1WU5 A;  3D5R A;  3QXQ A;  3W7W A;  3QFZ A;  1F9O A;  1QBQ B;  3Q73 B;  1H36 A;  2RGK A;  3OXU A;  2BED B;  3E6U A;  3P5P A;  1WZZ A;  3WUX A;  1S64 B;  1IA7 A;  3S4A A;  4LNG B;  4TF4 A;  2AFA A;  4AYO A;  2F6D A;  3RX8 A;  5MEH A;  4Q2B A;  1GHQ A;  1NC5 A;  3SDV A;  3OED A;  3ACT A;  1O1T B;  4WVB A;  1UG9 A;  5CZL A;  1V5C A;  3DSV B;  1O6R A;  3EU5 B;  4FXG B;  3G6J B;  1KZP B;  4MU9 A;  1CEM A;  5GZK A;  3WIQ A;  1GAI A;  1V7X A;  4D4C A;  2BB6 A;  3WC3 A;  2V8J A;  4WU0 A;  1VD5 A;  5FO7 B;  2ZBL A;  3DSW B;  1QSJ A;  1AYX A;  1SA4 B;  1KFG A;  1KSC A;  4V1R A;  3QT3 A;  3M76 A;  2FV1 A;  1HCU A;  1GLM A;  2BBC A;  3HXB B;  5JPM B;  1FAE A;  3C72 B;  3ACS A;  3M74 A;  4YCR A;  3RX7 A;  2PN5 A;  3ANI A;  2FBA A;  2JF4 A;  1IS9 A;  1TF4 A;  1JCS B;  1H3A A;  1X9D A;  2Z07 A;  5FOB B;  3SDT A;  3W7X A;  2DRS A;  1TNB B;  1XWT A;  1FCE A;  1W6K A;  3EU8 A;  3WKH A;  3GZK A;  2D5J A;  2WY7 A;  1DCE B;  4V1S A;  3AFJ A;  3S4B A;  3M73 A;  4ZH1 A;  1IA6 A;  3PYA A;  2DRQ A;  2JJB A;  3PZ1 B;  1H35 A;  1UMP A;  2ZZR A;  3Q79 B;  3H7L A;  4C1S A;  1O79 A;  3SFX B;  2H6F B;  4L0G A;  4XUV A;  1F9D A;  2V3P A;  4D4A A;  1TNU B;  4Z4L A;  1TN6 B;  2B4F A;  1FP3 A;  2D8L A;  1WU4 A;  1RQ5 A;  2VN7 A;  1QQF A;  1GSZ A;  3QFY A;  1H3B A;  1H3C A;  3H3K A;  1DL2 A;  2FUZ A;  3WIW A;  3Q7F B;  2DRO A;  1N95 B;  1TN8 B;  1V7V A;  3EZ8 A;  2GH4 A;  1XW2 A;  4LNV A;  1UT9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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