1L1YA

The crystal structure and catalytic mechanism of cellobiohydrolase cels, the major enzymatic component of the clostridium thermocellum cellulosome
Total Genus 229
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
229
sequence length
642
structure length
642
Chain Sequence
GPTKAPTKDGTSYKDLFLELYGKIKDPKNGYFSPDEGIPYHSIETLIVEAPDYGHVTTSEAFSYYVWLEAMYGNLTGNWSGVETAWKVMEDWIIPDSTEQPGMSSYNPNSPATYADEYEDPSYYPSELKFDTVRVGSDPVHNDLVSAYGPNMYLMHWLMDVDNWYGFGTGTRATFINTFQRGEQESTWETIPHPSIEEFKYGGPNGFLDLFTKDRSYAKQWRYTNAPDAEGRAIQAVYWANKWAKEQGKGSAVASVVSKAAKMGDFLRNDMFDKYFMKIGAQDKTPATGYDSAHYLMAWYTAWGGGIGASWAWKIGCSHAHFGYQNPFQGWVSATQSDFAPKSSNGKRDWTTSYKRQLEFYQWLQSAEGGIAGGATNSWNGRYEKYPAGTSTFYGMAYVPHPVYADPGSNQWFGFQAWSMQRVMEYYLETGDSSVKNLIKKWVDWVMSEIKLYDDGTFAIPSDLEWSGQPDTWTGTYTGNPNLHVRVTSYGTDLGVAGSLANALATYAAATERWEGKLDTKARDMAAELVNRAWYNFYCSEGKGVVTEEARADYKRFFEQEVYVPAGWSGTMPNGDKIQPGIKFIDIRTKYRQDPYYDIVYQAYLRGEAPVLNYHRFWHEVDLAVAMGVLATYFPDMTYKVP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords cellobiohydrolase
publication title The crystal structure and catalytic mechanism of cellobiohydrolase CelS, the major enzymatic component of the Clostridium thermocellum Cellulosome.
pubmed doi rcsb
source organism Clostridium thermocellum
total genus 229
structure length 642
sequence length 642
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.2.1.176: Cellulose 1,4-beta-cellobiosidase (reducing end).
pdb deposition date 2002-02-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02011 Glyco_hydro_48 Glycosyl hydrolase family 48
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.10 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1l1yA01
2.170.160.10 Mainly Beta Beta Complex Endo-1,4-beta-glucanase f; domain 2 Endo-1,4-beta-glucanase f. Domain 2 1l1yA02
4.10.870.10 Few Secondary Structures Irregular Endo-1,4-beta-glucanase f; domain 3 Endo-1,4-beta-glucanase f. Domain 3 1l1yA03
3QRYA 3GT5A 1IA7A 1KREA 3QSPA 2WYNA 1CLCA 1WU5A 1FO2A 5CZLA 1G87A 3WIRA 4KTRA 3A3VA 1GLMA 3S4DA 3CIHA 3ANJA 1IA6A 1VD5A 4L0GA 4J5TA 1GAHA 1NC5A 3VW5A 3WKGA 1RQ5A 2QNOA 2CQSA 2EAEA 2F6DA 4WU0A 5MEHA 4ZG8A 2RI9A 3QXQA 1F9OA 2RI8A 2Z07A 3RX7A 1FBWA 1WZZA 4AYQA 1H12A 1V7XA 5CD2A 3ACSA 1UG9A 2GH4A 4AYOA 3P2CA 2ZBLA 3RSYA 3H3KA 2OKXA 2RGKA 5GY3A 2JF4A 4KTPA 1KS8A 1H14A 1ULVA 2YIKA 1AGMA 3AFJA 1V5CA 5DGRA 2FBAA 1LF9A 4JJJA 2JG0A 1HCUA 1K72A 3H7LA 4CJ0A 1KSDA 3WIQA 3QWTA 4WVCA 3W5MA 4Z4JA 1NXCA 1XW2A 1WU6A 1DOGA 4Z4LA 2NVPA 2EACA 3QT9A 3S4BA 3W7TA 2AFAA 2D8LA 1AYXA 1G6IA 3WUXA 3W5NA 2B4FA 1H13A 4AYPA 3E73A 4DODA 3QG0A 4L6XA 2D5JA 1V5DA 1XWTA 1FBOA 2JJBA 3S4CA 4EL8A 1LF6A 2ZZRA 1GA2A 2FV1A 2VN7A 3EQAA 3QFZA 3PMMA 5DGQA 1IS9A 5M7IA 3ACTA 2DRQA 3QT3A 4TF4A 1L1YA 2GZ6A 3X17A 1KSCA 1L2AA 1V7WA 4XUVA 3QXFA 3RX5A 1JS4A 3W7SA 2EABA 1X9DA 5CA3A 4WVBA 1KWFA 5KKBA 1GAIA 3ANIA 1KKTA 3WKFA 1XWQA 1UT9A 1KFGA 2A8ZA 1KRFA 1FO3A 1F9DA 1TF4A 1H54A 5M7YA 2CQTA 3ANKA 3K11A 1FAEA 5E2JA 4Q2BA 3D3IA 4CJ1A 1CEMA 3T33A 1G9JA 3VXDA 1DL2A 2EADA 1WU4A 4WVAA 3S4AA 4DOEA 3E6UA 3TF4A 3WC3A 3WKIA 3QFYA 5GW7A 4Q88A 3W7UA 1FP3A 3RX8A 3H2WA 2DROA 2DRSA 4CE7A 2AHGA 2FUZA 3QDEA 3GLYA 2AHFA 1FMIA 3EZ8A 4FUSA 1FCEA 4ZH5A 3RENA 3W7XA 3ON6A 2VN4A 4TXTA 3WKHA 3QPFA 3RRSA 2FV0A 2XFGA 4AYRA 3W7WA 1V7VA 3GZKA 3WIWA 2DRRA 2P0VA 1G9GA
chains in the Genus database with same CATH superfamily
4D94A 3QSPA 1O6QA 3P5RA 1WU5A 1FO2A 4MMHA 1H37A 4MBGB 1W6JA 2ZISB 5CZLA 2G02A 2ONHA 4KTRA 3A3VA 4YDOB 1GXMA 3M02A 1IA6A 3K7XA 1GAHA 4J5TA 1RQ5A 2F6DA 4WU0A 2RI9A 2PN5A 2BEDB 1HM3A 3ACSA 1UG9A 4L9PB 3P2CA 2ZBLA 4AYOA 2WIIB 1JCRB 1ULVA 3SDTA 5IKAA 2V8IA 4OK2A 5DGRA 1TNZB 1K72A 1W6KA 3H7LA 1KSDA 3M7EA 4CJ0A 2NOJA 3DSWB 2BRWA 5JPNB 4GTPB 3E32B 3M01A 4WVCA 3W5MA 5JMFA 3M00A 1OJMA 4FXKB 4QT9A 2NVPA 2EACA 3QT9A 3W7TA 2BRPA 3SFXB 2D8LA 1LXKA 2BB6A 3M7CA 3E73A 3M71A 4OJZA 4L6XA 1DCEB 1O1TB 2GOXA 2I07B 1GA2A 4LNVA 2J5CA 3PZ3B 5DGQA 1FT2B 1JCSB 3QT3A 4TF4A 4ZH1A 1KSCA 3EUVB 2EABA 1N7NA 1JCQB 4GL3A 5GZKA 3SDVA 1XWQA 1N22A 3P5PA 4GTOB 4LNGB 1X81B 1H3BA 3KSQB 5IL3A 1FAEA 3Q73B 4OZWA 5E2JA 3HXDB 4Q2BA 1CEMA 3VSMA 4WVAA 3E6UA 3PZ1B 3TF4A 1HXAA 1N7QA 1OJNA 4RNQA 1LD7B 1HV6A 1LOHA 5IK6A 3GLYA 1FMIA 1FCEA 4ZH5A 1O6HA 3KQ4A 4BOKA 5IM1A 4FNVA 4V1RA 4D4CA 3WKHA 3DSXB 3RRSA 3SDQA 3W7WA 5ILKA 3WIWA 2IEJB 2DRRA 1LXMA 3QRYA 1IA7A 2F0YB 2R2LB 2WYNA 3Q79B 3Q75B 1CLCA 3M76A 1N20A 1N4SB 1N4PB 5ILIA 1G87A 3E80A 3NFVA 3WIRA 4GTSB 2WY7A 3ANJA 1N9AB 1NC5A 3EU5B 2EAEA 1RW9A 1N4QB 3M75A 4ZG8A 1F9OA 5IK0A 1WZZA 3OEDA 1H12A 1V7XA 1OJOA 4GTVB 3RSYA 1HN0A 2RGKA 2B39A 1KS8A 3M77A 3HXFB 1SQCA 1V5CA 2A73B 4JJJA 1HCUA 3M78A 3WIQA 3QWTA 5IKHA 4Z4JA 1XW2A 4OK4A 4LNBB 3SDRA 1RWCA 1HM2A 4LIXA 5JMDA 1G6IA 3A0OA 3WUXA 3DSSB 2B4FA 1H13A 1O1RB 2H6FB 4AYPA 2XWBB 4ZRQA 1SA4B 3G4FA 2D5JA 1XWTA 1FBOA 1O79A 4EL8A 2ZZRA 1GSZA 1TNOB 2VN7A 5JPMB 1HZFA 1IS9A 5M7IA 3PZ4B 2GZ6A 4KKIA 1X1HA 3RX5A 3W7SA 1JS4A 3PZ2B 3AFLA 4WVBA 3Q7AB 5KKBA 3KLSA 1KKTA 1UT9A 2V3PA 2A8ZA 1KRFA 1SA5B 5EASA 4OZVA 1FO3A 2WCOA 3E33B 1GHQA 1H54A 3SAEA 5M7YA 3ANKA 1HXGA 1H39A 1QQFA 2EADA 1NL4B 3DRAB 2H6HB 3WC3A 3QFYA 3DSTB 1N1BA 1HMWA 4DI5A 3M73A 1QBQB 3H2WA 5EAUA 2AHGA 1I8QA 1KZOB 3C72B 3QDEA 4MMIA 2AHFA 1C3DA 3SQCA 3LZ9A 3RENA 3W7XA 3E37B 3PYAA 2VN4A 1O1SB 4C1SA 2E24A 5ILHA 2FV0A 3DPYB 1J0MA 1V7VA 1HX9A 4YDEB 2PMVA 1N1ZA 4ONTA 3E30B 1HMUA 1N7OA 1GLMA 4GTQB 1S63B 1TNBB 2WY8A 4E1YA 3VW5A 3WKGA 1UMPA 4BOJA 2QNOA 2CQSA 1N4RB 2BRVX 2RI8A 4AYQA 5DHIA 2GH4A 3H3KA 4F13A 4KTPA 2E22A 1RWFA 5DHKA 2JG0A 4NEIA 1OJPA 1FPPB 1O6RA 1NXCA 3D5RA 5EATA 1DOGA 4Z4LA 2Q1FA 2SQCA 3S4BA 2AFAA 1GXNA 3HXBB 1H36A 1AYXA 1S64B 3W5NA 4V1SA 1N7PA 3N0FA 3E7JA 4KKJA 5ILYA 1V5DA 2JJBA 1LF6A 5C05A 2ZIRB 2FV1A 4FJQA 1QAZA 2V8JA 3QFZA 4EHMB 1TN6B 2DRQA 5ILJA 1RWHA 1L1YA 1R76A 2BBCA 3X17A 3N0GA 1X1JA 1L2AA 1FT1B 4XUVA 4D4BA 1N23A 3WKFA 4ZRPA 2XWJB 5ILDA 2BB5A 3Q7FB 5FO7B 1F9DA 3DSUB 2CQTA 4FXGB 1F9GA 4GTTB 3K11A 3E34B 3SFYB 1G9JA 1WU4A 1RWAA 4DOEA 1N21A 1X1IA 3WKIA 1FP3A 3RX8A 2DROA 2FUZA 5IL8A 5FO9B 4TXTA 3D5SA 3QPFA 4AYRA 3GZKA 4YCRA 2P0VA 1KZPB 3GT5A 1KREA 1J0NA 2H6IB 3VSNA 3S4DA 3CIHA 1H3AA 1VD5A 4L0GA 1C82A 3RJ3A 5MEHA 3QXQA 1N94B 1TNYB 2Z07A 1FBWA 3HXEB 3RX7A 1F1SA 5CD2A 1LD8B 2OKXA 5GY3A 2JF4A 1N7RA 5IK9A 2X03A 1H14A 2FUQA 2WINB 2YIKA 3M74A 1TNUB 3M72A 1AGMA 3AFJA 2FBAA 1LF9A 1TN7B 1N95B 2FUTA 2WDAA 2V8KA 1WU6A 3G4DA 3HXCB 3Q78B 1GXOA 3PYBA 5AGDA 3M7BA 5ILZA 2ONGA 4DODA 1H35A 3QG0A 4D4DA 3S4CA 3EU8A 4MU9A 4GTRB 1CB8A 1NI1B 3EQAA 2G0DA 3PMMA 3ACTA 1V7WA 3QXFA 1O5MB 1X9DA 5CA3A 4M76A 1KWFA 1GAIA 3ANIA 1D8DB 1KFGA 5FO8B 3G6JB 1TF4A 3KSLB 4GTMB 3NNBA 4GAXA 2V3NA 3M7LA 1MZCB 1TN8B 3S9VA 1EGUA 3D3IA 1LTXB 1H3CA 4F10A 1N24A 3T33A 4D4AA 4CJ1A 3VXDA 1DL2A 5FOBB 3S4AA 5GW7A 4Q88A 2H6GB 3W7UA 2DRSA 4CE7A 1RWGA 3EZ8A 4FUSA 3DSVB 1W3YA 3CU7A 2XQWA 3ON6A 3OXUA 1HXCA 3SDUA 2XFGA 1D8EB 1QSJA 1G9GA
chains in the Genus database with same CATH topology
4D94A 3QSPA 1O6QA 3P5RA 1WU5A 1FO2A 1H37A 4MBGB 1W6JA 2ZISB 5CZLA 2G02A 4KTRA 3A3VA 4YDOB 1GXMA 1IA6A 3K7XA 1GAHA 4J5TA 1RQ5A 2F6DA 4WU0A 2RI9A 2PN5A 2BEDB 3ACSA 1UG9A 4L9PB 3P2CA 2ZBLA 4AYOA 2WIIB 1JCRB 1ULVA 3SDTA 2V8IA 5DGRA 1TNZB 1K72A 1W6KA 3H7LA 1KSDA 3M7EA 4CJ0A 2NOJA 3DSWB 5JPNB 4GTPB 3E32B 4WVCA 3W5MA 4FXKB 4QT9A 2NVPA 2EACA 3QT9A 3W7TA 3SFXB 2D8LA 2BB6A 3M7CA 3E73A 3M71A 4L6XA 1DCEB 1O1TB 2GOXA 2I07B 1GA2A 4LNVA 3PZ3B 5DGQA 1FT2B 1JCSB 3QT3A 4TF4A 4ZH1A 1KSCA 3EUVB 2EABA 1JCQB 4GL3A 5GZKA 3SDVA 1XWQA 3P5PA 4GTOB 4LNGB 1X81B 1H3BA 3KSQB 1FAEA 3Q73B 5E2JA 3HXDB 4Q2BA 1CEMA 4WVAA 3E6UA 3PZ1B 3TF4A 1LD7B 3GLYA 1FMIA 1FCEA 4ZH5A 1O6HA 3KQ4A 4BOKA 4V1RA 4D4CA 3WKHA 3DSXB 3RRSA 3SDQA 3W7WA 3WIWA 2IEJB 2DRRA 3QRYA 1IA7A 2F0YB 2R2LB 2WYNA 3Q79B 3Q75B 1CLCA 3M76A 1N4SB 1N4PB 1G87A 3WIRA 4GTSB 2WY7A 3ANJA 1N9AB 1NC5A 3EU5B 2EAEA 1N4QB 3M75A 4ZG8A 1F9OA 1WZZA 3OEDA 1H12A 1V7XA 4GTVB 3RSYA 2RGKA 2B39A 1KS8A 3M77A 3HXFB 1SQCA 1V5CA 2A73B 4JJJA 1HCUA 3M78A 3WIQA 3QWTA 4Z4JA 1XW2A 4LNBB 3SDRA 4LIXA 1G6IA 3WUXA 3DSSB 2B4FA 1H13A 1O1RB 2H6FB 4AYPA 2XWBB 4ZRQA 1SA4B 2D5JA 1XWTA 1FBOA 1O79A 4EL8A 2ZZRA 1GSZA 1TNOB 2VN7A 5JPMB 1HZFA 1IS9A 5M7IA 3PZ4B 2GZ6A 4KKIA 3RX5A 3W7SA 1JS4A 3PZ2B 4WVBA 3Q7AB 5KKBA 3KLSA 1KKTA 1UT9A 2V3PA 2A8ZA 1KRFA 1SA5B 1FO3A 3E33B 1GHQA 1H54A 3SAEA 5M7YA 3ANKA 1H39A 1QQFA 2EADA 1NL4B 3DRAB 2H6HB 3WC3A 3QFYA 3DSTB 3M73A 1QBQB 3H2WA 2AHGA 1KZOB 3C72B 3QDEA 2AHFA 1C3DA 3SQCA 3RENA 3W7XA 3E37B 3PYAA 2VN4A 1O1SB 4C1SA 2FV0A 3DPYB 1V7VA 4YDEB 2PMVA 4ONTA 3E30B 1GLMA 4GTQB 1S63B 1TNBB 2WY8A 3VW5A 3WKGA 1UMPA 4BOJA 2QNOA 2CQSA 1N4RB 2RI8A 4AYQA 2GH4A 3H3KA 4KTPA 2JG0A 1FPPB 1O6RA 1NXCA 3D5RA 1DOGA 4Z4LA 2SQCA 3S4BA 2AFAA 1GXNA 3HXBB 1H36A 1AYXA 1S64B 3W5NA 4V1SA 4KKJA 1V5DA 2JJBA 1LF6A 2ZIRB 2FV1A 2V8JA 3QFZA 4EHMB 1TN6B 2DRQA 1L1YA 1R76A 2BBCA 3X17A 1L2AA 1FT1B 4XUVA 4D4BA 3WKFA 4ZRPA 2XWJB 2BB5A 3Q7FB 5FO7B 1F9DA 3DSUB 2CQTA 4FXGB 4GTTB 3K11A 3E34B 3SFYB 1G9JA 1WU4A 4DOEA 3WKIA 1FP3A 3RX8A 2DROA 2FUZA 5FO9B 4TXTA 3D5SA 3QPFA 4AYRA 3GZKA 4YCRA 2P0VA 1KZPB 3GT5A 1KREA 2H6IB 3S4DA 3CIHA 1H3AA 1VD5A 4L0GA 3RJ3A 5MEHA 3QXQA 1N94B 1TNYB 2Z07A 1FBWA 3HXEB 3RX7A 5CD2A 1LD8B 2OKXA 5GY3A 2JF4A 1H14A 2WINB 2YIKA 3M74A 1TNUB 3M72A 1AGMA 3AFJA 2FBAA 1LF9A 1TN7B 1N95B 2V8KA 1WU6A 3HXCB 3Q78B 1GXOA 3PYBA 5AGDA 3M7BA 4DODA 1H35A 3QG0A 4D4DA 3S4CA 3EU8A 4MU9A 4GTRB 1NI1B 3EQAA 2G0DA 3PMMA 3ACTA 1V7WA 3QXFA 1O5MB 1X9DA 5CA3A 4M76A 1KWFA 1GAIA 3ANIA 1D8DB 1KFGA 5FO8B 3G6JB 1TF4A 3KSLB 4GTMB 2V3NA 3M7LA 1MZCB 1TN8B 3S9VA 3D3IA 1LTXB 1H3CA 4CJ1A 3T33A 4D4AA 3VXDA 1DL2A 5FOBB 3S4AA 5GW7A 4Q88A 2H6GB 3W7UA 2DRSA 4CE7A 3EZ8A 4FUSA 3DSVB 3CU7A 2XQWA 3ON6A 3OXUA 3SDUA 2XFGA 1D8EB 1QSJA 1G9GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QRY A;  3GT5 A;  1IA7 A;  1KRE A;  3QSP A;  2WYN A;  1CLC A;  1WU5 A;  1FO2 A;  5CZL A;  1G87 A;  3WIR A;  4KTR A;  3A3V A;  1GLM A;  3S4D A;  3CIH A;  3ANJ A;  1IA6 A;  1VD5 A;  4L0G A;  4J5T A;  1GAH A;  1NC5 A;  3VW5 A;  3WKG A;  1RQ5 A;  2QNO A;  2CQS A;  2EAE A;  2F6D A;  4WU0 A;  5MEH A;  4ZG8 A;  2RI9 A;  3QXQ A;  1F9O A;  2RI8 A;  2Z07 A;  3RX7 A;  1FBW A;  1WZZ A;  4AYQ A;  1H12 A;  1V7X A;  5CD2 A;  3ACS A;  1UG9 A;  2GH4 A;  4AYO A;  3P2C A;  2ZBL A;  3RSY A;  3H3K A;  2OKX A;  2RGK A;  5GY3 A;  2JF4 A;  4KTP A;  1KS8 A;  1H14 A;  1ULV A;  2YIK A;  1AGM A;  3AFJ A;  1V5C A;  5DGR A;  2FBA A;  1LF9 A;  4JJJ A;  2JG0 A;  1HCU A;  1K72 A;  3H7L A;  4CJ0 A;  1KSD A;  3WIQ A;  3QWT A;  4WVC A;  3W5M A;  4Z4J A;  1NXC A;  1XW2 A;  1WU6 A;  1DOG A;  4Z4L A;  2NVP A;  2EAC A;  3QT9 A;  3S4B A;  3W7T A;  2AFA A;  2D8L A;  1AYX A;  1G6I A;  3WUX A;  3W5N A;  2B4F A;  1H13 A;  4AYP A;  3E73 A;  4DOD A;  3QG0 A;  4L6X A;  2D5J A;  1V5D A;  1XWT A;  1FBO A;  2JJB A;  3S4C A;  4EL8 A;  1LF6 A;  2ZZR A;  1GA2 A;  2FV1 A;  2VN7 A;  3EQA A;  3QFZ A;  3PMM A;  5DGQ A;  1IS9 A;  5M7I A;  3ACT A;  2DRQ A;  3QT3 A;  4TF4 A;  1L1Y A;  2GZ6 A;  3X17 A;  1KSC A;  1L2A A;  1V7W A;  4XUV A;  3QXF A;  3RX5 A;  1JS4 A;  3W7S A;  2EAB A;  1X9D A;  5CA3 A;  4WVB A;  1KWF A;  5KKB A;  1GAI A;  3ANI A;  1KKT A;  3WKF A;  1XWQ A;  1UT9 A;  1KFG A;  2A8Z A;  1KRF A;  1FO3 A;  1F9D A;  1TF4 A;  1H54 A;  5M7Y A;  2CQT A;  3ANK A;  3K11 A;  1FAE A;  5E2J A;  4Q2B A;  3D3I A;  4CJ1 A;  1CEM A;  3T33 A;  1G9J A;  3VXD A;  1DL2 A;  2EAD A;  1WU4 A;  4WVA A;  3S4A A;  4DOE A;  3E6U A;  3TF4 A;  3WC3 A;  3WKI A;  3QFY A;  5GW7 A;  4Q88 A;  3W7U A;  1FP3 A;  3RX8 A;  3H2W A;  2DRO A;  2DRS A;  4CE7 A;  2AHG A;  2FUZ A;  3QDE A;  3GLY A;  2AHF A;  1FMI A;  3EZ8 A;  4FUS A;  1FCE A;  4ZH5 A;  3REN A;  3W7X A;  3ON6 A;  2VN4 A;  4TXT A;  3WKH A;  3QPF A;  3RRS A;  2FV0 A;  2XFG A;  4AYR A;  3W7W A;  1V7V A;  3GZK A;  3WIW A;  2DRR A;  2P0V A;  1G9G A; 
#chains in the Genus database with same CATH topology
 4D94 A;  3QSP A;  1O6Q A;  3P5R A;  1WU5 A;  1FO2 A;  4MMH A;  1H37 A;  4MBG B;  1W6J A;  2ZIS B;  5CZL A;  2G02 A;  2ONH A;  4KTR A;  3A3V A;  4YDO B;  1GXM A;  3M02 A;  1IA6 A;  3K7X A;  1GAH A;  4J5T A;  1RQ5 A;  2F6D A;  4WU0 A;  2RI9 A;  2PN5 A;  2BED B;  1HM3 A;  3ACS A;  1UG9 A;  4L9P B;  3P2C A;  2ZBL A;  4AYO A;  2WII B;  1JCR B;  1ULV A;  3SDT A;  5IKA A;  2V8I A;  4OK2 A;  5DGR A;  1TNZ B;  1K72 A;  1W6K A;  3H7L A;  1KSD A;  3M7E A;  4CJ0 A;  2NOJ A;  3DSW B;  2BRW A;  5JPN B;  4GTP B;  3E32 B;  3M01 A;  4WVC A;  3W5M A;  5JMF A;  3M00 A;  1OJM A;  4FXK B;  4QT9 A;  2NVP A;  2EAC A;  3QT9 A;  3W7T A;  2BRP A;  3SFX B;  2D8L A;  1LXK A;  2BB6 A;  3M7C A;  3E73 A;  3M71 A;  4OJZ A;  4L6X A;  1DCE B;  1O1T B;  2GOX A;  2I07 B;  1GA2 A;  4LNV A;  2J5C A;  3PZ3 B;  5DGQ A;  1FT2 B;  1JCS B;  3QT3 A;  4TF4 A;  4ZH1 A;  1KSC A;  3EUV B;  2EAB A;  1N7N A;  1JCQ B;  4GL3 A;  5GZK A;  3SDV A;  1XWQ A;  1N22 A;  3P5P A;  4GTO B;  4LNG B;  1X81 B;  1H3B A;  3KSQ B;  5IL3 A;  1FAE A;  3Q73 B;  4OZW A;  5E2J A;  3HXD B;  4Q2B A;  1CEM A;  3VSM A;  4WVA A;  3E6U A;  3PZ1 B;  3TF4 A;  1HXA A;  1N7Q A;  1OJN A;  4RNQ A;  1LD7 B;  1HV6 A;  1LOH A;  5IK6 A;  3GLY A;  1FMI A;  1FCE A;  4ZH5 A;  1O6H A;  3KQ4 A;  4BOK A;  5IM1 A;  4FNV A;  4V1R A;  4D4C A;  3WKH A;  3DSX B;  3RRS A;  3SDQ A;  3W7W A;  5ILK A;  3WIW A;  2IEJ B;  2DRR A;  1LXM A;  3QRY A;  1IA7 A;  2F0Y B;  2R2L B;  2WYN A;  3Q79 B;  3Q75 B;  1CLC A;  3M76 A;  1N20 A;  1N4S B;  1N4P B;  5ILI A;  1G87 A;  3E80 A;  3NFV A;  3WIR A;  4GTS B;  2WY7 A;  3ANJ A;  1N9A B;  1NC5 A;  3EU5 B;  2EAE A;  1RW9 A;  1N4Q B;  3M75 A;  4ZG8 A;  1F9O A;  5IK0 A;  1WZZ A;  3OED A;  1H12 A;  1V7X A;  1OJO A;  4GTV B;  3RSY A;  1HN0 A;  2RGK A;  2B39 A;  1KS8 A;  3M77 A;  3HXF B;  1SQC A;  1V5C A;  2A73 B;  4JJJ A;  1HCU A;  3M78 A;  3WIQ A;  3QWT A;  5IKH A;  4Z4J A;  1XW2 A;  4OK4 A;  4LNB B;  3SDR A;  1RWC A;  1HM2 A;  4LIX A;  5JMD A;  1G6I A;  3A0O A;  3WUX A;  3DSS B;  2B4F A;  1H13 A;  1O1R B;  2H6F B;  4AYP A;  2XWB B;  4ZRQ A;  1SA4 B;  3G4F A;  2D5J A;  1XWT A;  1FBO A;  1O79 A;  4EL8 A;  2ZZR A;  1GSZ A;  1TNO B;  2VN7 A;  5JPM B;  1HZF A;  1IS9 A;  5M7I A;  3PZ4 B;  2GZ6 A;  4KKI A;  1X1H A;  3RX5 A;  3W7S A;  1JS4 A;  3PZ2 B;  3AFL A;  4WVB A;  3Q7A B;  5KKB A;  3KLS A;  1KKT A;  1UT9 A;  2V3P A;  2A8Z A;  1KRF A;  1SA5 B;  5EAS A;  4OZV A;  1FO3 A;  2WCO A;  3E33 B;  1GHQ A;  1H54 A;  3SAE A;  5M7Y A;  3ANK A;  1HXG A;  1H39 A;  1QQF A;  2EAD A;  1NL4 B;  3DRA B;  2H6H B;  3WC3 A;  3QFY A;  3DST B;  1N1B A;  1HMW A;  4DI5 A;  3M73 A;  1QBQ B;  3H2W A;  5EAU A;  2AHG A;  1I8Q A;  1KZO B;  3C72 B;  3QDE A;  4MMI A;  2AHF A;  1C3D A;  3SQC A;  3LZ9 A;  3REN A;  3W7X A;  3E37 B;  3PYA A;  2VN4 A;  1O1S B;  4C1S A;  2E24 A;  5ILH A;  2FV0 A;  3DPY B;  1J0M A;  1V7V A;  1HX9 A;  4YDE B;  2PMV A;  1N1Z A;  4ONT A;  3E30 B;  1HMU A;  1N7O A;  1GLM A;  4GTQ B;  1S63 B;  1TNB B;  2WY8 A;  4E1Y A;  3VW5 A;  3WKG A;  1UMP A;  4BOJ A;  2QNO A;  2CQS A;  1N4R B;  2BRV X;  2RI8 A;  4AYQ A;  5DHI A;  2GH4 A;  3H3K A;  4F13 A;  4KTP A;  2E22 A;  1RWF A;  5DHK A;  2JG0 A;  4NEI A;  1OJP A;  1FPP B;  1O6R A;  1NXC A;  3D5R A;  5EAT A;  1DOG A;  4Z4L A;  2Q1F A;  2SQC A;  3S4B A;  2AFA A;  1GXN A;  3HXB B;  1H36 A;  1AYX A;  1S64 B;  3W5N A;  4V1S A;  1N7P A;  3N0F A;  3E7J A;  4KKJ A;  5ILY A;  1V5D A;  2JJB A;  1LF6 A;  5C05 A;  2ZIR B;  2FV1 A;  4FJQ A;  1QAZ A;  2V8J A;  3QFZ A;  4EHM B;  1TN6 B;  2DRQ A;  5ILJ A;  1RWH A;  1L1Y A;  1R76 A;  2BBC A;  3X17 A;  3N0G A;  1X1J A;  1L2A A;  1FT1 B;  4XUV A;  4D4B A;  1N23 A;  3WKF A;  4ZRP A;  2XWJ B;  5ILD A;  2BB5 A;  3Q7F B;  5FO7 B;  1F9D A;  3DSU B;  2CQT A;  4FXG B;  1F9G A;  4GTT B;  3K11 A;  3E34 B;  3SFY B;  1G9J A;  1WU4 A;  1RWA A;  4DOE A;  1N21 A;  1X1I A;  3WKI A;  1FP3 A;  3RX8 A;  2DRO A;  2FUZ A;  5IL8 A;  5FO9 B;  4TXT A;  3D5S A;  3QPF A;  4AYR A;  3GZK A;  4YCR A;  2P0V A;  1KZP B;  3GT5 A;  1KRE A;  1J0N A;  2H6I B;  3VSN A;  3S4D A;  3CIH A;  1H3A A;  1VD5 A;  4L0G A;  1C82 A;  3RJ3 A;  5MEH A;  3QXQ A;  1N94 B;  1TNY B;  2Z07 A;  1FBW A;  3HXE B;  3RX7 A;  1F1S A;  5CD2 A;  1LD8 B;  2OKX A;  5GY3 A;  2JF4 A;  1N7R A;  5IK9 A;  2X03 A;  1H14 A;  2FUQ A;  2WIN B;  2YIK A;  3M74 A;  1TNU B;  3M72 A;  1AGM A;  3AFJ A;  2FBA A;  1LF9 A;  1TN7 B;  1N95 B;  2FUT A;  2WDA A;  2V8K A;  1WU6 A;  3G4D A;  3HXC B;  3Q78 B;  1GXO A;  3PYB A;  5AGD A;  3M7B A;  5ILZ A;  2ONG A;  4DOD A;  1H35 A;  3QG0 A;  4D4D A;  3S4C A;  3EU8 A;  4MU9 A;  4GTR B;  1CB8 A;  1NI1 B;  3EQA A;  2G0D A;  3PMM A;  3ACT A;  1V7W A;  3QXF A;  1O5M B;  1X9D A;  5CA3 A;  4M76 A;  1KWF A;  1GAI A;  3ANI A;  1D8D B;  1KFG A;  5FO8 B;  3G6J B;  1TF4 A;  3KSL B;  4GTM B;  3NNB A;  4GAX A;  2V3N A;  3M7L A;  1MZC B;  1TN8 B;  3S9V A;  1EGU A;  3D3I A;  1LTX B;  1H3C A;  4F10 A;  1N24 A;  3T33 A;  4D4A A;  4CJ1 A;  3VXD A;  1DL2 A;  5FOB B;  3S4A A;  5GW7 A;  4Q88 A;  2H6G B;  3W7U A;  2DRS A;  4CE7 A;  1RWG A;  3EZ8 A;  4FUS A;  3DSV B;  1W3Y A;  3CU7 A;  2XQW A;  3ON6 A;  3OXU A;  1HXC A;  3SDU A;  2XFG A;  1D8E B;  1QSJ A;  1G9G A; 
#chains in the Genus database with same CATH homology
 4D94 A;  3QSP A;  1O6Q A;  3P5R A;  1WU5 A;  1FO2 A;  1H37 A;  4MBG B;  1W6J A;  2ZIS B;  5CZL A;  2G02 A;  4KTR A;  3A3V A;  4YDO B;  1GXM A;  1IA6 A;  3K7X A;  1GAH A;  4J5T A;  1RQ5 A;  2F6D A;  4WU0 A;  2RI9 A;  2PN5 A;  2BED B;  3ACS A;  1UG9 A;  4L9P B;  3P2C A;  2ZBL A;  4AYO A;  2WII B;  1JCR B;  1ULV A;  3SDT A;  2V8I A;  5DGR A;  1TNZ B;  1K72 A;  1W6K A;  3H7L A;  1KSD A;  3M7E A;  4CJ0 A;  2NOJ A;  3DSW B;  5JPN B;  4GTP B;  3E32 B;  4WVC A;  3W5M A;  4FXK B;  4QT9 A;  2NVP A;  2EAC A;  3QT9 A;  3W7T A;  3SFX B;  2D8L A;  2BB6 A;  3M7C A;  3E73 A;  3M71 A;  4L6X A;  1DCE B;  1O1T B;  2GOX A;  2I07 B;  1GA2 A;  4LNV A;  3PZ3 B;  5DGQ A;  1FT2 B;  1JCS B;  3QT3 A;  4TF4 A;  4ZH1 A;  1KSC A;  3EUV B;  2EAB A;  1JCQ B;  4GL3 A;  5GZK A;  3SDV A;  1XWQ A;  3P5P A;  4GTO B;  4LNG B;  1X81 B;  1H3B A;  3KSQ B;  1FAE A;  3Q73 B;  5E2J A;  3HXD B;  4Q2B A;  1CEM A;  4WVA A;  3E6U A;  3PZ1 B;  3TF4 A;  1LD7 B;  3GLY A;  1FMI A;  1FCE A;  4ZH5 A;  1O6H A;  3KQ4 A;  4BOK A;  4V1R A;  4D4C A;  3WKH A;  3DSX B;  3RRS A;  3SDQ A;  3W7W A;  3WIW A;  2IEJ B;  2DRR A;  3QRY A;  1IA7 A;  2F0Y B;  2R2L B;  2WYN A;  3Q79 B;  3Q75 B;  1CLC A;  3M76 A;  1N4S B;  1N4P B;  1G87 A;  3WIR A;  4GTS B;  2WY7 A;  3ANJ A;  1N9A B;  1NC5 A;  3EU5 B;  2EAE A;  1N4Q B;  3M75 A;  4ZG8 A;  1F9O A;  1WZZ A;  3OED A;  1H12 A;  1V7X A;  4GTV B;  3RSY A;  2RGK A;  2B39 A;  1KS8 A;  3M77 A;  3HXF B;  1SQC A;  1V5C A;  2A73 B;  4JJJ A;  1HCU A;  3M78 A;  3WIQ A;  3QWT A;  4Z4J A;  1XW2 A;  4LNB B;  3SDR A;  4LIX A;  1G6I A;  3WUX A;  3DSS B;  2B4F A;  1H13 A;  1O1R B;  2H6F B;  4AYP A;  2XWB B;  4ZRQ A;  1SA4 B;  2D5J A;  1XWT A;  1FBO A;  1O79 A;  4EL8 A;  2ZZR A;  1GSZ A;  1TNO B;  2VN7 A;  5JPM B;  1HZF A;  1IS9 A;  5M7I A;  3PZ4 B;  2GZ6 A;  4KKI A;  3RX5 A;  3W7S A;  1JS4 A;  3PZ2 B;  4WVB A;  3Q7A B;  5KKB A;  3KLS A;  1KKT A;  1UT9 A;  2V3P A;  2A8Z A;  1KRF A;  1SA5 B;  1FO3 A;  3E33 B;  1GHQ A;  1H54 A;  3SAE A;  5M7Y A;  3ANK A;  1H39 A;  1QQF A;  2EAD A;  1NL4 B;  3DRA B;  2H6H B;  3WC3 A;  3QFY A;  3DST B;  3M73 A;  1QBQ B;  3H2W A;  2AHG A;  1KZO B;  3C72 B;  3QDE A;  2AHF A;  1C3D A;  3SQC A;  3REN A;  3W7X A;  3E37 B;  3PYA A;  2VN4 A;  1O1S B;  4C1S A;  2FV0 A;  3DPY B;  1V7V A;  4YDE B;  2PMV A;  4ONT A;  3E30 B;  1GLM A;  4GTQ B;  1S63 B;  1TNB B;  2WY8 A;  3VW5 A;  3WKG A;  1UMP A;  4BOJ A;  2QNO A;  2CQS A;  1N4R B;  2RI8 A;  4AYQ A;  2GH4 A;  3H3K A;  4KTP A;  2JG0 A;  1FPP B;  1O6R A;  1NXC A;  3D5R A;  1DOG A;  4Z4L A;  2SQC A;  3S4B A;  2AFA A;  1GXN A;  3HXB B;  1H36 A;  1AYX A;  1S64 B;  3W5N A;  4V1S A;  4KKJ A;  1V5D A;  2JJB A;  1LF6 A;  2ZIR B;  2FV1 A;  2V8J A;  3QFZ A;  4EHM B;  1TN6 B;  2DRQ A;  1L1Y A;  1R76 A;  2BBC A;  3X17 A;  1L2A A;  1FT1 B;  4XUV A;  4D4B A;  3WKF A;  4ZRP A;  2XWJ B;  2BB5 A;  3Q7F B;  5FO7 B;  1F9D A;  3DSU B;  2CQT A;  4FXG B;  4GTT B;  3K11 A;  3E34 B;  3SFY B;  1G9J A;  1WU4 A;  4DOE A;  3WKI A;  1FP3 A;  3RX8 A;  2DRO A;  2FUZ A;  5FO9 B;  4TXT A;  3D5S A;  3QPF A;  4AYR A;  3GZK A;  4YCR A;  2P0V A;  1KZP B;  3GT5 A;  1KRE A;  2H6I B;  3S4D A;  3CIH A;  1H3A A;  1VD5 A;  4L0G A;  3RJ3 A;  5MEH A;  3QXQ A;  1N94 B;  1TNY B;  2Z07 A;  1FBW A;  3HXE B;  3RX7 A;  5CD2 A;  1LD8 B;  2OKX A;  5GY3 A;  2JF4 A;  1H14 A;  2WIN B;  2YIK A;  3M74 A;  1TNU B;  3M72 A;  1AGM A;  3AFJ A;  2FBA A;  1LF9 A;  1TN7 B;  1N95 B;  2V8K A;  1WU6 A;  3HXC B;  3Q78 B;  1GXO A;  3PYB A;  5AGD A;  3M7B A;  4DOD A;  1H35 A;  3QG0 A;  4D4D A;  3S4C A;  3EU8 A;  4MU9 A;  4GTR B;  1NI1 B;  3EQA A;  2G0D A;  3PMM A;  3ACT A;  1V7W A;  3QXF A;  1O5M B;  1X9D A;  5CA3 A;  4M76 A;  1KWF A;  1GAI A;  3ANI A;  1D8D B;  1KFG A;  5FO8 B;  3G6J B;  1TF4 A;  3KSL B;  4GTM B;  2V3N A;  3M7L A;  1MZC B;  1TN8 B;  3S9V A;  3D3I A;  1LTX B;  1H3C A;  4CJ1 A;  3T33 A;  4D4A A;  3VXD A;  1DL2 A;  5FOB B;  3S4A A;  5GW7 A;  4Q88 A;  2H6G B;  3W7U A;  2DRS A;  4CE7 A;  3EZ8 A;  4FUS A;  3DSV B;  3CU7 A;  2XQW A;  3ON6 A;  3OXU A;  3SDU A;  2XFG A;  1D8E B;  1QSJ A;  1G9G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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