4MMIA

Crystal structure of heparan sulfate lyase hepc mutant from pedobacter heparinus
Total Genus 222
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
222
sequence length
636
structure length
636
Chain Sequence
VTRKDFDHINLEYSGLEKVNKAVAAGNYDDAAKALLAYYREKSKAREPDFSNAEKPADIRQPIDKVTREMADKALVHQFQPHKGYGYFDYGKDINWQMWPVKDNEVRWQLHRVKWWQAMALVYHATGDEKYAREWVYQYSDWARKNPLGLSQDNDKFVWRPLEVSDRVQSLPPTFSLFVNSPAFTPAFLMEFLNSYHQQADYLSTHYAEQGNHRLFEAQRNLFAGVSFPEFKDSPRWRQTGISVLNTEIKKQVYADGMQFELSPIYHVAAIDIFLKAYGSAKRVNLEKEFPQSYVQTVENMIMALISISLPDYNTPMFGDSWITDKNFRMAQFASWARVFPANQAIKYFATDGKQGKAPNFLSKALSNAGFYTFRSGWDKNATVMVLKASPPGEFHAQPDNGTFELFIKGRNFTPDAGVFVYSGDEAIMKLRNWYRQTRIHSTLTLDNQNMVITKARQNKWETGNNLDVLTYTNPSYPNLDHQRSVLFINKKYFLVIDRAIGEATGNLGVHWQLKEDSNPVFDKTKNRVYTTYRDGNNLMIQSLNADRTSLNEEEGKVSYVYNKELKRPAFVFEKPKKNAGTQNFVSIVYPYDGQKAPEISIRENKGNDFEKGKLNLTLTINGKQQLVSVPLEHHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Lyase
molecule keywords Heparinase III protein
publication title Crystal Structure of Pedobacter heparinus Heparin Lyase Hep III with the Active Site in a Deep Cleft
pubmed doi rcsb
source organism Pedobacter heparinus
total genus 222
structure length 636
sequence length 636
ec nomenclature ec 4.2.2.8: Heparin-sulfate lyase.
pdb deposition date 2013-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07940 Hepar_II_III Heparinase II/III-like protein
A PF16889 Hepar_II_III_N Heparinase II/III N-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 4mmiA01
2.70.98.70 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 4mmiA02
1HV6A 1HMWA 4F13A 2FUQA 4NEIA 1LXKA 1EGUA 1RWAA 1X1HA 3VSNA 1CB8A 2X03A 1LOHA 5JMDA 4MMIA 2WCOA 1C82A 2BRPA 2Q1FA 4OJZA 4OZVA 1RWHA 1RW9A 1X1IA 4E1YA 4F10A 1X1JA 1N7QA 1N7RA 1N7OA 2E24A 1HM3A 2WDAA 4OZWA 1F1SA 1RWGA 1LXMA 1HM2A 5JMFA 1OJNA 1OJPA 3A0OA 1OJOA 2BRWA 2FUTA 4FNVA 1OJMA 1QAZA 2E22A 1J0MA 1I8QA 1RWCA 1HN0A 1J0NA 3E7JA 4OK4A 3VSMA 1RWFA 4OK2A 1N7PA 1W3YA 2BRVX 3NNBA 1HMUA 3AFLA 3NFVA 4MMHA 1N7NA 3E80A 1F9GA
chains in the Genus database with same CATH superfamily
1NI1B 3M02A 3M75A 2PNCA 2OKXA 1PS3A 1TNYB 3QFZA 1IA6A 1FP3A 1KWFA 3M76A 3QRYA 3HIIA 2BEDB 2G02A 1X1JA 4AYPA 3DX0A 1KREA 2YFNA 1JCRB 2WVXA 5ILZA 1V7XA 2D73A 2A8ZA 1NSUA 2P0VA 1IVWA 1NSRA 1SIHA 5E2JA 3T0BA 4GTMB 2RGKA 3C72B 3P5PA 3BS6A 1KZPB 2CQTA 5M7YA 3BVUA 3OS7A 3Q1NA 3OXUA 4QT9A 3HXCB 4GTPB 1JCSB 1HV6A 2F7RA 3S4DA 3I3DA 1NKGA 1TNBB 1EGUA 3PYBA 2XN0A 1C82A 3HI7A 1H3CA 4FNRA 2BT3A 1MMXA 3PGBA 2JJBA 2E24A 4FUSA 1JCQB 1FCEA 1AGMA 1GA2A 4OZWA 3WA2X 1H13A 4EV5A 3BVVA 2V8JA 1N22A 1OJOA 2V3PA 3EQAA 3RX7A 1Z45A 2JKEA 3DSSB 1V7VA 3SDUA 3CZNA 4OK4A 1S63B 3X41A 3M7LA 1W7CA 2RDYA 1H3AA 4DUXA 2DROA 3T08A 4CJ0A 3QT9A 3WKHA 5IKAA 2F7OA 2CQSA 3RX5A 3SAEA 2ZXQA 4YDOB 3SDRA 3WKGA 4AYQA 2J5CA 1L7JA 1SQCA 1TN7B 5IK0A 4D4AA 1TQUA 1H39A 3VD5A 3M72A 3E37B 3S4AA 2NOJA 3D5SA 1JZ6A 4LNGB 1NXCA 2CFGA 1F4AA 4YDEB 1TXKA 4BOKA 1HM2A 2WOFA 5A1AA 3WIQA 2BRWA 1JYNA 2YIKA 5FOBB 4DUVA 3H2WA 1RQ5A 1R33A 4ZH1A 1NSMA 1TQTA 1JS4A 3G4FA 1HMUA 3A3VA 4GTSB 4KTRA 1SPUA 2WVZA 2DRQA 1HTYA 1N7NA 1O1RB 3E6UA 4WU0A 3ALAA 3GT5A 4AYRA 4NEIA 3CV5A 1KSDA 1HN1A 1NSZA 2OOVC 4OZVA 1LD8B 2XN1A 2VN7A 1IQYA 4TF4A 1MMZA 3EJPA 5IK9A 5DHKA 3DX2A 1YQ2A 5ILHA 3WC3A 4D94A 4EL8A 4FNPA 3TY1A 3WIRA 1N4PB 3D51A 1N24A 4GAXA 2BB5A 5C05A 3DX1A 1AYXA 3QFYA 1TNZB 4AQ0A 2QNOA 2XWBB 3WKIA 3E30B 2CG1A 5FO8B 3RX8A 2ZISB 2HTAA 3G6JB 1SA5B 1V5DA 1TQSA 2FBAA 1UG9A 2F0YB 2EABA 3PYAA 1HCUA 2Y73A 1HX9A 5IL8A 3NJXA 1N1BA 1PU4A 4MMIA 1WU4A 2ZQ0A 3E34B 1W5ZA 1FBWA 2G0DA 3SQCA 3EJSA 4GTTB 1RWGA 4MBGB 2WO0A 5JPNB 3VD4A 2IEJB 2WYNA 1HXKA 1KFGA 5FO9B 1TQWA 1JZ7A 5GW7A 1LF9A 2H6HB 2WGQA 4TTGA 2ONGA 3E33B 3M7CA 3T0DA 4L9PB 3IMHA 2EADA 3DDFA 3LOYA 1ULVA 3K7XA 3AFLA 3D3IA 5DGQA 4EHMB 4XUVA 1NSXA 2B4FA 1LURA 4KTPA 2WW0A 3GZKA 1LXKA 2AHFA 5ILDA 3HIGA 3KQ4A 3EU5B 2WCOA 3QG0A 2CFLA 1MN0A 3MUY1 3N0FA 5ILKA 4J5TA 2JF4A 4DOEA 1QAFA 3J7HA 1L7KA 1GXOA 3OEDA 3X17A 2E2UA 1HXGA 3S9VA 1SO0A 1OJPA 4GL3A 2V8KA 4CE7A 1WMOA 3E1F1 1FMIA 5M7IA 4DUWA 3CZJA 2BB6A 3BUIA 3VSMA 2FYVA 2OW6A 3BVTA 3D5RA 1MMUA 3VXDA 1SIIA 3I3BA 3M74A 3RRSA 5KKBA 3S4CA 2F7PA 3DYPA 3QXFA 3WUXA 1A2VA 1N95B 3VSNA 2WW2A 1R76A 4ZRQA 1GXMA 1H35A 1N4RB 2OW7A 2WYIA 2F7QA 1HWWA 3TF4A 1JZ8A 4BTYA 1D6UA 4L6XA 2RI9A 3PMMA 1LVNA 1W6CA 2WY7A 3DSUB 3PZ2B 4V1SA 5JMFA 3EUVB 2OOVA 1W6KA 3QWTA 3SFYB 4GTOB 2C10A 1TF4A 3SDVA 2H6FB 3CU7A 1FBOA 2ZBLA 1RWFA 3D52A 1C3DA 2CFDA 3MPHA 2A73B 5AGDA 3DPYB 2CIQA 1QSJA 1FO2A 3W7WA 1QAKA 3BLBA 5IK6A 5JPMB 4K35A 3X40A 4ONTA 3Q73B 1DP0A 2E2TA 2X03A 1FO3A 3M7EA 3IAPA 2GH4A 1AVLA 1MMYA 1US1A 1VD5A 5CZLA 3MV01 4KFFA 1N7RA 1N7OA 1IQXA 1FAEA 3KSQB 3WIWA 3A0OA 3M00A 4RNQA 3EJQA 1J0NA 4L0GA 3BUDA 1O1TB 2BRVX 4BZHA 3ACTA 2XQWA 2V3NA 3ANIA 3NNBA 3KN4A 3VD9A 2PN5A 2CWTA 1X9DA 1F9GA 1O7DD 3PZ4B 3BVWA 3H7LA 1L1YA 1K1WA 1TNUB 1KZOB 1SA4B 3OB8A 1WZZA 2FUZA 2OQEC 1DYUA 1KSIA 1FT2B 1O1SB 1W2ZA 2D5JA 3HXEB 1HM3A 3HXBB 3DYMA 4D4BA 4D4CA 2RI8A 1LTXB 3M7BA 3X3YA 3W7XA 2E22A 1UI7A 1I8QA 3QSPA 4BZFA 2CIRA 2JKAA 1R34A 1NSSA 1W3YA 1L2AA 1QBQB 2WIIB 3T09A 3M71A 4BZEA 4RNLA 1NS2A 3EJTA 1N1ZA 4WVCA 4FJQA 1QWNA 2FV0A 1D8DB 4F13A 3I3EA 2FUQA 3QT3A 4KKJA 3HXFB 3ANKA 1F9OA 4ZG8A 4E1YA 2WINB 3WVFA 3ON6A 3MV11 3M73A 1DL2A 1F1SA 1OJNA 5ILJA 2WW3A 3MWXA 4UFCA 3A24A 1CEMA 1EKMA 1OJMA 2Y74A 1J0MA 2B39A 1G87A 1HN0A 4TXTA 3W7SA 4WVBA 3PZ3B 3OBAA 3WKFA 2CFWA 4D4DA 2CFKA 4BTWA 3VDAA 1JYXA 3E73A 3SFXB 2F1BA 5GY3A 1K1YA 3NREA 4BZGA 3ANJA 1N21A 3BVXA 1W6JA 3K5TA 1CB8A 3D4YA 2WVYA 1WU6A 3ECQA 1IA7A 1O6QA 1JZ5A 3Q75B 1IVXA 3T2PA 1N7QA 3BUPA 1D8EB 2XHNA 3EJRA 2WDAA 1F4HA 3D4ZA 5FO7B 1G9JA 5CD2A 3VD7A 4BTXA 3BLCA 1KKTA 4LNVA 3E32B 3RENA 3LVTA 4C1SA 1DCEB 3T33A 5IL3A 1IVUA 1HZFA 5ILIA 1XWTA 3DYOA 1W4NA 3M01A 5EASA 3E80A 1JZ4A 1JRQA 3SXXA 4FXKB 3VDCA 2EACA 3KLSA 2WZSA 3RJ3A 5ILYA 3X3ZA 1JZ3A 4Z4JA 1AVKA 1RWHA 1OACA 3BGAA 1RKYA 1UI8A 2ZZRA 4Z4LA 2C11A 1JZ2A 2OQEA 3KSLB 3QXQA 2DRRA 3SDQA 3T2QA 1N4SB 3CIHA 1KSCA 4LIXA 2SQCA 4DODA 1NS0A 1SNZA 4FNSA 3T2OA 3E7JA 1H12A 1H3BA 1QALA 3NBJA 1JYVA 3SEPA 1N7PA 5GZKA 5EAUA 3EJUA 3Q78B 3NFVA 4Q88A 1WMNA 1WMPA 4ZRPA 1GAHA 3Q7FB 1HMWA 5DGRA 5CA3A 1H14A 3P5RA 3HXDB 1PX4A 1YGAA 2WY8A 4GTRB 4FNQA 1N94B 3W7TA 2JKPA 2HTBA 4FNTA 1S64B 2BRPA 2H6IB 4OJZA 1D6ZA 1IS9A 1NSVA 3VDBA 1F9DA 3Q7AB 3G4DA 1AV4A 4KFDA 3VW5A 1NS4A 3LZ9A 1MZCB 2ZL8A 3DX3A 3WA3A 1UMPA 4DI5A 3DRAB 1K1XA 3PZ1B 4OK2A 1UT9A 4YCRA 3ACSA 3BUQA 2XWJB 1GLMA 2XFGA 4M76A 4WVAA 2XN2A 3BUBA 3IAQA 4KKIA 2CISA 1N20A 1O5MB 1X81B 2F6DA 4FNUA 3SDTA 3DSWB 1N23A 3EU8A 3QDEA 2ALWA 2V8IA 1X1HA 1NL4B 3DECA 3KIIA 1TN6B 5JMDA 2Q1FA 3X42A 1V7WA 1V5CA 3CZSA 1DOGA 1FT1B 5EATA 3N9HA 1LXMA 3MUZ1 3DDGA 5E1QA 3DSTB 1O6RA 2WYHA 1H36A 3T0UA 4FNVA 1FPPB 3H3KA 3RSYA 2AHGA 1XWQA 5IM1A 1LF6A 2F1AA 2H6GB 1TQVA 3S4BA 3SX1A 3AFJA 2CG0A 4JJJA 1N4QB 2ZIRB 1CLCA 2R2LB 4LNBB 2D1WA 1D6YA 1XW2A 3MI6A 1H37A 3NBBA 3W5MA 2VN4A 3M77A 1NC5A 4K3AA 3NJVA 4BOJA 2WOHA 3P2CA 5KBPA 4GTVB 1RW9A 1X1IA 2GZ6A 2Z07A 1HXAA 1QQFA 1JOVA 1G6IA 1N9EA 2F18A 5IKHA 1JYWA 2BBCA 3DSXB 1NS7A 1KS8A 1LD7B 4ZH5A 1TN8B 4AYOA 2DRSA 3Q79B 3EZ8A 1N9AB 1IVVA 2FV1A 2W0QA 3M78A 3W5NA 3DX4A 1RJOA 1HXCA 3K25A 4KFEA 1QWUA 5DHIA 1GXNA 3N0GA 2E2VA 2PMVA 4MMHA 3DCDA 2GOXA 3D50A 3K11A 3VD3A 3QPFA 1NS8A 1IU7A 1RWAA 5MEHA 3AMOB 1LOHA 2I07B 2CWVA 2WW1A 1WU5A 4FXGB 4CJ1A 3GLYA 1GSZA 4F10A 2NVPA 1K72A 3T0AA 2D8LA 1TNOB 2ONHA 2CWUA 3W7UA 1O79A 1PX3A 2XSGA 1O6HA 3WFAA 1KRFA 4MU9A 2JG0A 2YFOA 2YX9A 2FUTA 1H54A 1QAZA 1GHQA 1RWCA 2AFAA 4V1RA 4EV2A 1G9GA 4GTQB 2WVXB 3X3XA 1GAIA 2EAEA 4Q2BA 1W6GA 1QX1A 1TU5A 3DSVB 3AMOA
chains in the Genus database with same CATH topology
1HMWA 1K1WA 1PX4A 1YGAA 1UG9A 3OB8A 3NJXA 2JKPA 2HTBA 4MMIA 2BRPA 2ZQ0A 4OJZA 1NSVA 3VDBA 1X1JA 1HM3A 3DYMA 1RWGA 1NS4A 2WVXA 3VD4A 2D73A 2E22A 4BZFA 1I8QA 1NSUA 1JZ7A 1K1XA 1LF9A 2CIRA 2JKAA 1NSRA 4OK2A 1NSSA 1W3YA 4TTGA 3T0DA 3IMHA 3T0BA 3IAQA 3T09A 1ULVA 3BS6A 4BZEA 4RNLA 3AFLA 1NS2A 3OS7A 3Q1NA 2CISA 1NSXA 1HV6A 1LURA 4F13A 3I3EA 2FUQA 2WW0A 3I3DA 1LXKA 1NKGA 1EGUA 1X1HA 3DECA 5JMDA 2WCOA 1C82A 2Q1FA 1MN0A 3MUY1 4J5TA 4E1YA 1MMXA 3WVFA 3J7HA 2E24A 3MV11 1L7KA 4OZWA 1F1SA 3MUZ1 1LXMA 5E1QA 1OJNA 2WW3A 1SO0A 1OJPA 3MWXA 3A24A 3E1F1 1OJOA 1Z45A 2JKEA 4FNVA 1OJMA 4DUWA 1J0MA 4OK4A 3CZJA 1HN0A 3VSMA 3OBAA 4DUXA 1LF6A 3T08A 2ZXQA 3I3BA 1MMUA 3VDAA 1JYXA 3DYPA 1L7JA 3NREA 1K1YA 4BZGA 3VSNA 3VD5A 1CB8A 2WW2A 1JZ6A 3NJVA 2WVYA 3ECQA 1RW9A 1X1IA 1JZ5A 1JZ8A 3T2PA 1N7QA 1F4AA 1JOVA 1TXKA 2XHNA 2WDAA 1F4HA 1JYWA 1NS7A 1HM2A 5JMFA 3VD7A 5A1AA 3BLCA 2BRWA 1JYNA 4DUVA 1RWFA 3K25A 1NSMA 3DYOA 1HMUA 3DCDA 4MMHA 2WVZA 2CIQA 1N7NA 3E80A 3VD3A 1JZ4A 1NS8A 4NEIA 1DP0A 1RWAA 3VDCA 2WZSA 2X03A 1HN1A 1LOHA 3IAPA 1MMYA 1NSZA 2WW1A 1JZ3A 4OZVA 3BGAA 1RWHA 3MV01 1MMZA 4F10A 1JZ2A 1N7RA 1N7OA 3T0AA 1YQ2A 2XSGA 1PX3A 3A0OA 3T2QA 3WFAA 2FUTA 1NS0A 1QAZA 1SNZA 3TY1A 1RWCA 3T2OA 1J0NA 3E7JA 1JYVA 2WVXB 3SEPA 1N7PA 2BRVX 4BZHA 3NNBA 3VD9A 4AQ0A 3NFVA 2HTAA 1F9GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HV6 A;  1HMW A;  4F13 A;  2FUQ A;  4NEI A;  1LXK A;  1EGU A;  1RWA A;  1X1H A;  3VSN A;  1CB8 A;  2X03 A;  1LOH A;  5JMD A;  4MMI A;  2WCO A;  1C82 A;  2BRP A;  2Q1F A;  4OJZ A;  4OZV A;  1RWH A;  1RW9 A;  1X1I A;  4E1Y A;  4F10 A;  1X1J A;  1N7Q A;  1N7R A;  1N7O A;  2E24 A;  1HM3 A;  2WDA A;  4OZW A;  1F1S A;  1RWG A;  1LXM A;  1HM2 A;  5JMF A;  1OJN A;  1OJP A;  3A0O A;  1OJO A;  2BRW A;  2FUT A;  4FNV A;  1OJM A;  1QAZ A;  2E22 A;  1J0M A;  1I8Q A;  1RWC A;  1HN0 A;  1J0N A;  3E7J A;  4OK4 A;  3VSM A;  1RWF A;  4OK2 A;  1N7P A;  1W3Y A;  2BRV X;  3NNB A;  1HMU A;  3AFL A;  3NFV A;  4MMH A;  1N7N A;  3E80 A;  1F9G A; 
#chains in the Genus database with same CATH topology
 1NI1 B;  3M02 A;  3M75 A;  2PNC A;  2OKX A;  1PS3 A;  1TNY B;  3QFZ A;  1IA6 A;  1FP3 A;  1KWF A;  3M76 A;  3QRY A;  3HII A;  2BED B;  2G02 A;  1X1J A;  4AYP A;  3DX0 A;  1KRE A;  2YFN A;  1JCR B;  2WVX A;  5ILZ A;  1V7X A;  2D73 A;  2A8Z A;  1NSU A;  2P0V A;  1IVW A;  1NSR A;  1SIH A;  5E2J A;  3T0B A;  4GTM B;  2RGK A;  3C72 B;  3P5P A;  3BS6 A;  1KZP B;  2CQT A;  5M7Y A;  3BVU A;  3OS7 A;  3Q1N A;  3OXU A;  4QT9 A;  3HXC B;  4GTP B;  1JCS B;  1HV6 A;  2F7R A;  3S4D A;  3I3D A;  1NKG A;  1TNB B;  1EGU A;  3PYB A;  2XN0 A;  1C82 A;  3HI7 A;  1H3C A;  4FNR A;  2BT3 A;  1MMX A;  3PGB A;  2JJB A;  2E24 A;  4FUS A;  1JCQ B;  1FCE A;  1AGM A;  1GA2 A;  4OZW A;  3WA2 X;  1H13 A;  4EV5 A;  3BVV A;  2V8J A;  1N22 A;  1OJO A;  2V3P A;  3EQA A;  3RX7 A;  1Z45 A;  2JKE A;  3DSS B;  1V7V A;  3SDU A;  3CZN A;  4OK4 A;  1S63 B;  3X41 A;  3M7L A;  1W7C A;  2RDY A;  1H3A A;  4DUX A;  2DRO A;  3T08 A;  4CJ0 A;  3QT9 A;  3WKH A;  5IKA A;  2F7O A;  2CQS A;  3RX5 A;  3SAE A;  2ZXQ A;  4YDO B;  3SDR A;  3WKG A;  4AYQ A;  2J5C A;  1L7J A;  1SQC A;  1TN7 B;  5IK0 A;  4D4A A;  1TQU A;  1H39 A;  3VD5 A;  3M72 A;  3E37 B;  3S4A A;  2NOJ A;  3D5S A;  1JZ6 A;  4LNG B;  1NXC A;  2CFG A;  1F4A A;  4YDE B;  1TXK A;  4BOK A;  1HM2 A;  2WOF A;  5A1A A;  3WIQ A;  2BRW A;  1JYN A;  2YIK A;  5FOB B;  4DUV A;  3H2W A;  1RQ5 A;  1R33 A;  4ZH1 A;  1NSM A;  1TQT A;  1JS4 A;  3G4F A;  1HMU A;  3A3V A;  4GTS B;  4KTR A;  1SPU A;  2WVZ A;  2DRQ A;  1HTY A;  1N7N A;  1O1R B;  3E6U A;  4WU0 A;  3ALA A;  3GT5 A;  4AYR A;  4NEI A;  3CV5 A;  1KSD A;  1HN1 A;  1NSZ A;  2OOV C;  4OZV A;  1LD8 B;  2XN1 A;  2VN7 A;  1IQY A;  4TF4 A;  1MMZ A;  3EJP A;  5IK9 A;  5DHK A;  3DX2 A;  1YQ2 A;  5ILH A;  3WC3 A;  4D94 A;  4EL8 A;  4FNP A;  3TY1 A;  3WIR A;  1N4P B;  3D51 A;  1N24 A;  4GAX A;  2BB5 A;  5C05 A;  3DX1 A;  1AYX A;  3QFY A;  1TNZ B;  4AQ0 A;  2QNO A;  2XWB B;  3WKI A;  3E30 B;  2CG1 A;  5FO8 B;  3RX8 A;  2ZIS B;  2HTA A;  3G6J B;  1SA5 B;  1V5D A;  1TQS A;  2FBA A;  1UG9 A;  2F0Y B;  2EAB A;  3PYA A;  1HCU A;  2Y73 A;  1HX9 A;  5IL8 A;  3NJX A;  1N1B A;  1PU4 A;  4MMI A;  1WU4 A;  2ZQ0 A;  3E34 B;  1W5Z A;  1FBW A;  2G0D A;  3SQC A;  3EJS A;  4GTT B;  1RWG A;  4MBG B;  2WO0 A;  5JPN B;  3VD4 A;  2IEJ B;  2WYN A;  1HXK A;  1KFG A;  5FO9 B;  1TQW A;  1JZ7 A;  5GW7 A;  1LF9 A;  2H6H B;  2WGQ A;  4TTG A;  2ONG A;  3E33 B;  3M7C A;  3T0D A;  4L9P B;  3IMH A;  2EAD A;  3DDF A;  3LOY A;  1ULV A;  3K7X A;  3AFL A;  3D3I A;  5DGQ A;  4EHM B;  4XUV A;  1NSX A;  2B4F A;  1LUR A;  4KTP A;  2WW0 A;  3GZK A;  1LXK A;  2AHF A;  5ILD A;  3HIG A;  3KQ4 A;  3EU5 B;  2WCO A;  3QG0 A;  2CFL A;  1MN0 A;  3MUY 1;  3N0F A;  5ILK A;  4J5T A;  2JF4 A;  4DOE A;  1QAF A;  3J7H A;  1L7K A;  1GXO A;  3OED A;  3X17 A;  2E2U A;  1HXG A;  3S9V A;  1SO0 A;  1OJP A;  4GL3 A;  2V8K A;  4CE7 A;  1WMO A;  3E1F 1;  1FMI A;  5M7I A;  4DUW A;  3CZJ A;  2BB6 A;  3BUI A;  3VSM A;  2FYV A;  2OW6 A;  3BVT A;  3D5R A;  1MMU A;  3VXD A;  1SII A;  3I3B A;  3M74 A;  3RRS A;  5KKB A;  3S4C A;  2F7P A;  3DYP A;  3QXF A;  3WUX A;  1A2V A;  1N95 B;  3VSN A;  2WW2 A;  1R76 A;  4ZRQ A;  1GXM A;  1H35 A;  1N4R B;  2OW7 A;  2WYI A;  2F7Q A;  1HWW A;  3TF4 A;  1JZ8 A;  4BTY A;  1D6U A;  4L6X A;  2RI9 A;  3PMM A;  1LVN A;  1W6C A;  2WY7 A;  3DSU B;  3PZ2 B;  4V1S A;  5JMF A;  3EUV B;  2OOV A;  1W6K A;  3QWT A;  3SFY B;  4GTO B;  2C10 A;  1TF4 A;  3SDV A;  2H6F B;  3CU7 A;  1FBO A;  2ZBL A;  1RWF A;  3D52 A;  1C3D A;  2CFD A;  3MPH A;  2A73 B;  5AGD A;  3DPY B;  2CIQ A;  1QSJ A;  1FO2 A;  3W7W A;  1QAK A;  3BLB A;  5IK6 A;  5JPM B;  4K35 A;  3X40 A;  4ONT A;  3Q73 B;  1DP0 A;  2E2T A;  2X03 A;  1FO3 A;  3M7E A;  3IAP A;  2GH4 A;  1AVL A;  1MMY A;  1US1 A;  1VD5 A;  5CZL A;  3MV0 1;  4KFF A;  1N7R A;  1N7O A;  1IQX A;  1FAE A;  3KSQ B;  3WIW A;  3A0O A;  3M00 A;  4RNQ A;  3EJQ A;  1J0N A;  4L0G A;  3BUD A;  1O1T B;  2BRV X;  4BZH A;  3ACT A;  2XQW A;  2V3N A;  3ANI A;  3NNB A;  3KN4 A;  3VD9 A;  2PN5 A;  2CWT A;  1X9D A;  1F9G A;  1O7D D;  3PZ4 B;  3BVW A;  3H7L A;  1L1Y A;  1K1W A;  1TNU B;  1KZO B;  1SA4 B;  3OB8 A;  1WZZ A;  2FUZ A;  2OQE C;  1DYU A;  1KSI A;  1FT2 B;  1O1S B;  1W2Z A;  2D5J A;  3HXE B;  1HM3 A;  3HXB B;  3DYM A;  4D4B A;  4D4C A;  2RI8 A;  1LTX B;  3M7B A;  3X3Y A;  3W7X A;  2E22 A;  1UI7 A;  1I8Q A;  3QSP A;  4BZF A;  2CIR A;  2JKA A;  1R34 A;  1NSS A;  1W3Y A;  1L2A A;  1QBQ B;  2WII B;  3T09 A;  3M71 A;  4BZE A;  4RNL A;  1NS2 A;  3EJT A;  1N1Z A;  4WVC A;  4FJQ A;  1QWN A;  2FV0 A;  1D8D B;  4F13 A;  3I3E A;  2FUQ A;  3QT3 A;  4KKJ A;  3HXF B;  3ANK A;  1F9O A;  4ZG8 A;  4E1Y A;  2WIN B;  3WVF A;  3ON6 A;  3MV1 1;  3M73 A;  1DL2 A;  1F1S A;  1OJN A;  5ILJ A;  2WW3 A;  3MWX A;  4UFC A;  3A24 A;  1CEM A;  1EKM A;  1OJM A;  2Y74 A;  1J0M A;  2B39 A;  1G87 A;  1HN0 A;  4TXT A;  3W7S A;  4WVB A;  3PZ3 B;  3OBA A;  3WKF A;  2CFW A;  4D4D A;  2CFK A;  4BTW A;  3VDA A;  1JYX A;  3E73 A;  3SFX B;  2F1B A;  5GY3 A;  1K1Y A;  3NRE A;  4BZG A;  3ANJ A;  1N21 A;  3BVX A;  1W6J A;  3K5T A;  1CB8 A;  3D4Y A;  2WVY A;  1WU6 A;  3ECQ A;  1IA7 A;  1O6Q A;  1JZ5 A;  3Q75 B;  1IVX A;  3T2P A;  1N7Q A;  3BUP A;  1D8E B;  2XHN A;  3EJR A;  2WDA A;  1F4H A;  3D4Z A;  5FO7 B;  1G9J A;  5CD2 A;  3VD7 A;  4BTX A;  3BLC A;  1KKT A;  4LNV A;  3E32 B;  3REN A;  3LVT A;  4C1S A;  1DCE B;  3T33 A;  5IL3 A;  1IVU A;  1HZF A;  5ILI A;  1XWT A;  3DYO A;  1W4N A;  3M01 A;  5EAS A;  3E80 A;  1JZ4 A;  1JRQ A;  3SXX A;  4FXK B;  3VDC A;  2EAC A;  3KLS A;  2WZS A;  3RJ3 A;  5ILY A;  3X3Z A;  1JZ3 A;  4Z4J A;  1AVK A;  1RWH A;  1OAC A;  3BGA A;  1RKY A;  1UI8 A;  2ZZR A;  4Z4L A;  2C11 A;  1JZ2 A;  2OQE A;  3KSL B;  3QXQ A;  2DRR A;  3SDQ A;  3T2Q A;  1N4S B;  3CIH A;  1KSC A;  4LIX A;  2SQC A;  4DOD A;  1NS0 A;  1SNZ A;  4FNS A;  3T2O A;  3E7J A;  1H12 A;  1H3B A;  1QAL A;  3NBJ A;  1JYV A;  3SEP A;  1N7P A;  5GZK A;  5EAU A;  3EJU A;  3Q78 B;  3NFV A;  4Q88 A;  1WMN A;  1WMP A;  4ZRP A;  1GAH A;  3Q7F B;  1HMW A;  5DGR A;  5CA3 A;  1H14 A;  3P5R A;  3HXD B;  1PX4 A;  1YGA A;  2WY8 A;  4GTR B;  4FNQ A;  1N94 B;  3W7T A;  2JKP A;  2HTB A;  4FNT A;  1S64 B;  2BRP A;  2H6I B;  4OJZ A;  1D6Z A;  1IS9 A;  1NSV A;  3VDB A;  1F9D A;  3Q7A B;  3G4D A;  1AV4 A;  4KFD A;  3VW5 A;  1NS4 A;  3LZ9 A;  1MZC B;  2ZL8 A;  3DX3 A;  3WA3 A;  1UMP A;  4DI5 A;  3DRA B;  1K1X A;  3PZ1 B;  4OK2 A;  1UT9 A;  4YCR A;  3ACS A;  3BUQ A;  2XWJ B;  1GLM A;  2XFG A;  4M76 A;  4WVA A;  2XN2 A;  3BUB A;  3IAQ A;  4KKI A;  2CIS A;  1N20 A;  1O5M B;  1X81 B;  2F6D A;  4FNU A;  3SDT A;  3DSW B;  1N23 A;  3EU8 A;  3QDE A;  2ALW A;  2V8I A;  1X1H A;  1NL4 B;  3DEC A;  3KII A;  1TN6 B;  5JMD A;  2Q1F A;  3X42 A;  1V7W A;  1V5C A;  3CZS A;  1DOG A;  1FT1 B;  5EAT A;  3N9H A;  1LXM A;  3MUZ 1;  3DDG A;  5E1Q A;  3DST B;  1O6R A;  2WYH A;  1H36 A;  3T0U A;  4FNV A;  1FPP B;  3H3K A;  3RSY A;  2AHG A;  1XWQ A;  5IM1 A;  1LF6 A;  2F1A A;  2H6G B;  1TQV A;  3S4B A;  3SX1 A;  3AFJ A;  2CG0 A;  4JJJ A;  1N4Q B;  2ZIR B;  1CLC A;  2R2L B;  4LNB B;  2D1W A;  1D6Y A;  1XW2 A;  3MI6 A;  1H37 A;  3NBB A;  3W5M A;  2VN4 A;  3M77 A;  1NC5 A;  4K3A A;  3NJV A;  4BOJ A;  2WOH A;  3P2C A;  5KBP A;  4GTV B;  1RW9 A;  1X1I A;  2GZ6 A;  2Z07 A;  1HXA A;  1QQF A;  1JOV A;  1G6I A;  1N9E A;  2F18 A;  5IKH A;  1JYW A;  2BBC A;  3DSX B;  1NS7 A;  1KS8 A;  1LD7 B;  4ZH5 A;  1TN8 B;  4AYO A;  2DRS A;  3Q79 B;  3EZ8 A;  1N9A B;  1IVV A;  2FV1 A;  2W0Q A;  3M78 A;  3W5N A;  3DX4 A;  1RJO A;  1HXC A;  3K25 A;  4KFE A;  1QWU A;  5DHI A;  1GXN A;  3N0G A;  2E2V A;  2PMV A;  4MMH A;  3DCD A;  2GOX A;  3D50 A;  3K11 A;  3VD3 A;  3QPF A;  1NS8 A;  1IU7 A;  1RWA A;  5MEH A;  3AMO B;  1LOH A;  2I07 B;  2CWV A;  2WW1 A;  1WU5 A;  4FXG B;  4CJ1 A;  3GLY A;  1GSZ A;  4F10 A;  2NVP A;  1K72 A;  3T0A A;  2D8L A;  1TNO B;  2ONH A;  2CWU A;  3W7U A;  1O79 A;  1PX3 A;  2XSG A;  1O6H A;  3WFA A;  1KRF A;  4MU9 A;  2JG0 A;  2YFO A;  2YX9 A;  2FUT A;  1H54 A;  1QAZ A;  1GHQ A;  1RWC A;  2AFA A;  4V1R A;  4EV2 A;  1G9G A;  4GTQ B;  2WVX B;  3X3X A;  1GAI A;  2EAE A;  4Q2B A;  1W6G A;  1QX1 A;  1TU5 A;  3DSV B;  3AMO A; 
#chains in the Genus database with same CATH homology
 1HMW A;  1K1W A;  1PX4 A;  1YGA A;  1UG9 A;  3OB8 A;  3NJX A;  2JKP A;  2HTB A;  4MMI A;  2BRP A;  2ZQ0 A;  4OJZ A;  1NSV A;  3VDB A;  1X1J A;  1HM3 A;  3DYM A;  1RWG A;  1NS4 A;  2WVX A;  3VD4 A;  2D73 A;  2E22 A;  4BZF A;  1I8Q A;  1NSU A;  1JZ7 A;  1K1X A;  1LF9 A;  2CIR A;  2JKA A;  1NSR A;  4OK2 A;  1NSS A;  1W3Y A;  4TTG A;  3T0D A;  3IMH A;  3T0B A;  3IAQ A;  3T09 A;  1ULV A;  3BS6 A;  4BZE A;  4RNL A;  3AFL A;  1NS2 A;  3OS7 A;  3Q1N A;  2CIS A;  1NSX A;  1HV6 A;  1LUR A;  4F13 A;  3I3E A;  2FUQ A;  2WW0 A;  3I3D A;  1LXK A;  1NKG A;  1EGU A;  1X1H A;  3DEC A;  5JMD A;  2WCO A;  1C82 A;  2Q1F A;  1MN0 A;  3MUY 1;  4J5T A;  4E1Y A;  1MMX A;  3WVF A;  3J7H A;  2E24 A;  3MV1 1;  1L7K A;  4OZW A;  1F1S A;  3MUZ 1;  1LXM A;  5E1Q A;  1OJN A;  2WW3 A;  1SO0 A;  1OJP A;  3MWX A;  3A24 A;  3E1F 1;  1OJO A;  1Z45 A;  2JKE A;  4FNV A;  1OJM A;  4DUW A;  1J0M A;  4OK4 A;  3CZJ A;  1HN0 A;  3VSM A;  3OBA A;  4DUX A;  1LF6 A;  3T08 A;  2ZXQ A;  3I3B A;  1MMU A;  3VDA A;  1JYX A;  3DYP A;  1L7J A;  3NRE A;  1K1Y A;  4BZG A;  3VSN A;  3VD5 A;  1CB8 A;  2WW2 A;  1JZ6 A;  3NJV A;  2WVY A;  3ECQ A;  1RW9 A;  1X1I A;  1JZ5 A;  1JZ8 A;  3T2P A;  1N7Q A;  1F4A A;  1JOV A;  1TXK A;  2XHN A;  2WDA A;  1F4H A;  1JYW A;  1NS7 A;  1HM2 A;  5JMF A;  3VD7 A;  5A1A A;  3BLC A;  2BRW A;  1JYN A;  4DUV A;  1RWF A;  3K25 A;  1NSM A;  3DYO A;  1HMU A;  3DCD A;  4MMH A;  2WVZ A;  2CIQ A;  1N7N A;  3E80 A;  3VD3 A;  1JZ4 A;  1NS8 A;  4NEI A;  1DP0 A;  1RWA A;  3VDC A;  2WZS A;  2X03 A;  1HN1 A;  1LOH A;  3IAP A;  1MMY A;  1NSZ A;  2WW1 A;  1JZ3 A;  4OZV A;  3BGA A;  1RWH A;  3MV0 1;  1MMZ A;  4F10 A;  1JZ2 A;  1N7R A;  1N7O A;  3T0A A;  1YQ2 A;  2XSG A;  1PX3 A;  3A0O A;  3T2Q A;  3WFA A;  2FUT A;  1NS0 A;  1QAZ A;  1SNZ A;  3TY1 A;  1RWC A;  3T2O A;  1J0N A;  3E7J A;  1JYV A;  2WVX B;  3SEP A;  1N7P A;  2BRV X;  4BZH A;  3NNB A;  3VD9 A;  4AQ0 A;  3NFV A;  2HTA A;  1F9G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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