1JCSB

Crystal structure of rat protein farnesyltransferase complexed with the peptide substrate tkcvfm and an analog of farnesyl diphosphate
Total Genus 150
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
407
structure length
407
Chain Sequence
PVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Rattus norvegicus
molecule keywords PROTEIN FARNESYLTRANSFERASE, ALPHA SUBUNIT
total genus 150
structure length 407
sequence length 407
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2001-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1jcsB00
1D8EB 4D4DA 1O6RA 3RJ3A 1NL4B 4GTPB 1QBQB 2SQCA 1HZFA 3E32B 2ZISB 2BB5A 2XWBB 1TNYB 4MBGB 1FT1B 1TNUB 1SA5B 1SA4B 2PMVA 4BOKA 1MZCB 1TNOB 3CU7A 3HXCB 1TNZB 4M76A 3HXDB 1W6KA 3PZ3B 2NOJA 2WIIB 3Q79B 3DPYB 3KSQB 1H36A 3DSXB 1O5MB 1QQFA 1JCSB 3DSSB 4GTSB 1TNBB 1H3CA 4GTMB 4LNBB 3G6JB 4LNVA 5JPNB 5JPMB 2GOXA 2PN5A 3K7XA 3OXUA 1N95B 1LD7B 3SFXB 1GXMA 5FOBB 4ZRQA 4LNGB 3PZ4B 2H6GB 4D94A 4FXKB 2B39A 3C72B 3DSUB 1X81B 2V8IA 2V3PA 2H6HB 1TN6B 4MU9A 1H39A 1O1SB 2I07B 1O6QA 4V1RA 1H35A 3Q78B 2WY7A 1DCEB 3E33B 1W6JA 4GTQB 5FO9B 1QSJA 4GTOB 4ZH1A 3D5SA 4FXGB 1JCRB 4C1SA 1SQCA 3HXBB 3DSVB 5FO7B 2A73B 2G0DA 4YDOB 1UMPA 1NI1B 3EUVB 5FO8B 2G02A 3D5RA 2XQWA 1KZOB 1N9AB 1O79A 4GTVB 3Q75B 4BOJA 2F0YB 2IEJB 4GTTB 1TN8B 1KZPB 2BB6A 2V8JA 1C3DA 1H3AA 1H37A 3HXFB 1N4QB 2ZIRB 1O1TB 1LD8B 1N4SB 1R76A 3KLSA 4YDEB 3Q7AB 3DSWB 3EU5B 1S64B 4ONTA 1JCQB 4D4AA 2H6FB 1FT2B 2WINB 3DRAB 3E30B 3SQCA 2WY8A 3DSTB 3HXEB 3KSLB 1N4PB 2R2LB 4D4CA 2XWJB 1N4RB 5AGDA 1O1RB 3E37B 2H6IB 1O6HA 2BEDB 1GHQA 3PZ2B 1TN7B 1S63B 3OEDA 4GTRB 1N94B 4KKJA 3Q73B 3KQ4A 1D8DB 2BBCA 2V8KA 4ZRPA 3SFYB 1FPPB 1GXOA 3E34B 3PZ1B 1LTXB 1GSZA 1H3BA 4EHMB 4KKIA 4D4BA 2V3NA 4L9PB 1GXNA 4V1SA 3Q7FB
chains in the Genus database with same CATH superfamily
4AYQA 1NL4B 3M78A 1NC5A 3RRSA 1HMWA 1WZZA 3AFJA 4KTRA 1OJOA 2ZISB 2BB5A 1TNYB 3W5NA 4L0GA 4F13A 1SA4B 2WDAA 1N24A 1LOHA 3HXDB 1GAIA 3PZ3B 3M74A 1KSCA 3Q79B 3KSQB 1H36A 3QXFA 1QQFA 1H54A 1JCSB 1H3CA 4LNBB 2FUQA 3G6JB 3PMMA 3SDTA 1TF4A 2PN5A 3S4DA 3ANIA 4ZRQA 4LNGB 3PZ4B 3NNBA 1LXMA 3RX5A 1RWHA 2H6HB 1TN6B 5M7IA 3WKGA 1KWFA 3QXQA 1L2AA 3SDUA 4FXGB 3EZ8A 3E7JA 1KS8A 4KTPA 4C1SA 1VD5A 1K72A 3HXBB 3DSVB 5FO7B 2CQSA 2G0DA 4L6XA 1UMPA 3EUVB 4EL8A 3D5RA 3E73A 1KZOB 4WVAA 1CB8A 3GT5A 3QT9A 4GTVB 2A8ZA 3WKIA 1CEMA 1IA7A 2BB6A 3X17A 1C3DA 1I8QA 5C05A 2ZIRB 3M00A 3EU5B 3QFZA 4ONTA 1QAZA 4GL3A 5E2JA 3QDEA 3WIQA 2FBAA 2R2LB 5CD2A 5AGDA 4NEIA 3NFVA 3GZKA 3W7XA 1O6HA 2BEDB 3ACSA 5CA3A 3M7BA 4LIXA 1DL2A 5EAUA 1N7NA 1W3YA 5GY3A 4OJZA 1H12A 4KKIA 1HX9A 4E1YA 2FUTA 4L9PB 1N7RA 1GXNA 3Q7FB 4D4DA 3RJ3A 1N1ZA 3S4BA 2ONGA 5ILYA 1FBOA 4XUVA 4MBGB 1KSDA 4BOKA 1MZCB 1TNOB 4DODA 1X1HA 2J5CA 1W6KA 3S4CA 1N7OA 1FMIA 3W7WA 3EQAA 2Q1FA 2RI8A 1DOGA 1WU4A 3PYBA 1X1IA 5JMDA 1XWQA 1FAEA 1XW2A 5GW7A 4FNVA 5EASA 4Z4LA 3W5MA 1HCUA 3H3KA 2H6GB 1JS4A 1V5DA 5IK9A 5IL8A 2V3PA 1H13A 2I07B 2FV0A 1H35A 1N1BA 2FUZA 1IS9A 3WKFA 2AFAA 1WU6A 3ON6A 3E33B 1KREA 3T33A 5FO9B 3RENA 1GLMA 3PYAA 1NXCA 1G9JA 4Q88A 2FV1A 3EU8A 2WCOA 3GLYA 1NI1B 4CJ0A 1L1YA 1N9AB 2ONHA 3Q75B 4BOJA 2IEJB 1KZPB 3M01A 4GAXA 2V8JA 3M72A 1H3AA 1H37A 3WUXA 5IM1A 1V7VA 3P5RA 1LD8B 1N4SB 1N20A 4YDEB 1HXGA 1G6IA 3QRYA 3WKHA 1FO3A 5IKHA 2NVPA 1N23A 4OK4A 2F6DA 4D4AA 2H6FB 2D5JA 2WINB 3DRAB 3HXEB 1N4PB 4D4CA 2EAEA 1J0MA 1HN0A 3G4FA 1J0NA 1RWGA 4GTRB 1N94B 5DGRA 1V7WA 1D8DB 4WVBA 4ZRPA 3SDQA 1AGMA 2DROA 5ILKA 3WIRA 3D3IA 1LTXB 3RX7A 3M7CA 4D4BA 3G4DA 3RX8A 1RWAA 3QPFA 2E24A 1HM2A 3VXDA 4GTPB 1QBQB 1HZFA 1HV6A 5ILHA 2BRVX 2XWBB 1FT1B 1F9DA 2WYNA 1G87A 2Z07A 3H7LA 5ILJA 5DGQA 4M76A 4Q2BA 1RWFA 1KKTA 3N0GA 5M7YA 3DSXB 4GTSB 4OZWA 1N21A 2JG0A 1F9OA 5JPMB 5JPNB 3K7XA 3OXUA 1IA6A 1FBWA 1OJMA 2AHFA 4JJJA 2ZBLA 1LD7B 3TF4A 1FP3A 1GXMA 2RGKA 4OZVA 4D94A 4FXKB 3A3VA 1CLCA 3S4AA 1X81B 1GAHA 1V5CA 4MMHA 4YCRA 3K11A 3SDVA 3ANKA 4F10A 1H39A 1O1SB 4V1RA 3ANJA 3VW5A 3M7EA 2WY7A 1N7QA 4GTQB 3VSMA 3H2WA 1KFGA 5ILZA 4GTOB 4ZH1A 3D5SA 4DI5A 2E22A 2GZ6A 1RQ5A 1H14A 4YDOB 5FO8B 4MMIA 1O79A 1X9DA 3SDRA 4GTTB 5IK0A 2X03A 3P5PA 1O1TB 4RNQA 1R76A 3Q7AB 3M76A 3AFLA 5CZLA 5KKBA 3VSNA 4Z4JA 2QNOA 2WY8A 3DSTB 2EACA 1G9GA 1N4RB 1O1RB 2H6IB 1OJPA 1GHQA 5JMFA 3PZ2B 1TN7B 3QG0A 3QT3A 1LF6A 1S63B 1FO2A 3KQ4A 4FUSA 1N22A 1HXCA 3E34B 1N7PA 4CJ1A 3QWTA 4AYPA 2V3NA 1HXAA 1LXKA 1UT9A 3A0OA 3LZ9A 3QFYA 3M75A 5ILDA 1D8EB 1O6RA 1F1SA 2B4FA 1F9GA 4DOEA 2SQCA 3E32B 2VN7A 4AYOA 1TNUB 1SA5B 3M02A 2PMVA 3CU7A 3HXCB 1TNZB 2DRRA 3P2CA 4WU0A 3M7LA 2EABA 2NOJA 2WIIB 4J5TA 1GA2A 3DPYB 1RW9A 4TF4A 5DHKA 1O5MB 3DSSB 5IKAA 1TNBB 4GTMB 4LNVA 2GOXA 2AHGA 3E80A 5DHIA 1AYXA 1FCEA 1N95B 2D8LA 2P0VA 3M71A 3SFXB 5FOBB 2DRSA 2XFGA 2B39A 3C72B 3DSUB 2BRPA 4ZG8A 4WVCA 2V8IA 3S9VA 3M77A 4MU9A 4OK2A 5IK6A 1O6QA 3M73A 3Q78B 1DCEB 5ILIA 1W6JA 1QSJA 1UG9A 3WIWA 1JCRB 3WC3A 1SQCA 2VN4A 2A73B 3ACTA 2DRQA 2G02A 2XQWA 1ULVA 3CIHA 2GH4A 3W7TA 2F0YB 1TN8B 4FJQA 4ZH5A 3HXFB 1N4QB 1OJNA 2JJBA 3KLSA 2YIKA 4QT9A 1KRFA 2CQTA 2EADA 3DSWB 1V7XA 2ZZRA 1S64B 1JCQB 3RSYA 1XWTA 1FT2B 3E30B 3SQCA 5EATA 1LF9A 3KSLB 5IL3A 2XWJB 1C82A 2BRWA 3E37B 1HMUA 4AYRA 3W7UA 3QSPA 4TXTA 3OEDA 1X1JA 4KKJA 5MEHA 3Q73B 2BBCA 2V8KA 3N0FA 4CE7A 3SFYB 1FPPB 2OKXA 1GXOA 3PZ1B 5GZKA 1WU5A 1GSZA 1H3BA 4EHMB 1HM3A 3W7SA 1EGUA 1RWCA 3E6UA 3SAEA 2RI9A 4V1SA 2JF4A
chains in the Genus database with same CATH topology
4AYQA 1NL4B 3M78A 1NC5A 3RRSA 1WZZA 3AFJA 4KTRA 2ZISB 2BB5A 1TNYB 3W5NA 4L0GA 1SA4B 3HXDB 1GAIA 3PZ3B 3M74A 1KSCA 3Q79B 3KSQB 1H36A 3QXFA 1QQFA 1H54A 1JCSB 1H3CA 4LNBB 3PMMA 3G6JB 3SDTA 1TF4A 2PN5A 3S4DA 3ANIA 4ZRQA 4LNGB 3PZ4B 3RX5A 2H6HB 1TN6B 5M7IA 3WKGA 1KWFA 3QXQA 1L2AA 3SDUA 4FXGB 3EZ8A 1KS8A 4KTPA 4C1SA 1VD5A 1K72A 3HXBB 3DSVB 5FO7B 2CQSA 2G0DA 4L6XA 1UMPA 3EUVB 4EL8A 3D5RA 3E73A 1KZOB 4WVAA 3GT5A 3QT9A 4GTVB 2A8ZA 3WKIA 1CEMA 1IA7A 2BB6A 3X17A 1C3DA 2ZIRB 3EU5B 3QFZA 4ONTA 4GL3A 5E2JA 3QDEA 3WIQA 2FBAA 2R2LB 5CD2A 5AGDA 3GZKA 3W7XA 1O6HA 2BEDB 3ACSA 5CA3A 3M7BA 4LIXA 1DL2A 5GY3A 1H12A 4KKIA 4L9PB 1GXNA 3Q7FB 4D4DA 3RJ3A 3S4BA 1FBOA 4XUVA 4MBGB 1KSDA 4BOKA 1MZCB 1TNOB 4DODA 1W6KA 3S4CA 1FMIA 3W7WA 3EQAA 2RI8A 1DOGA 1WU4A 3PYBA 1XWQA 1FAEA 1XW2A 5GW7A 4Z4LA 3W5MA 1HCUA 3H3KA 2H6GB 1JS4A 1V5DA 2V3PA 1H13A 2I07B 2FV0A 1H35A 2FUZA 3WKFA 1IS9A 2AFAA 1WU6A 3ON6A 3E33B 1KREA 3T33A 5FO9B 3RENA 1GLMA 3PYAA 1NXCA 1G9JA 4Q88A 2FV1A 3EU8A 3GLYA 1NI1B 4CJ0A 1L1YA 1N9AB 3Q75B 4BOJA 2IEJB 1KZPB 2V8JA 3M72A 1H3AA 1H37A 3WUXA 1V7VA 3P5RA 1LD8B 1N4SB 4YDEB 3QRYA 1G6IA 3WKHA 1FO3A 2NVPA 2F6DA 4D4AA 2H6FB 2D5JA 2WINB 3DRAB 3HXEB 1N4PB 4D4CA 2EAEA 4GTRB 1N94B 5DGRA 1V7WA 1D8DB 4WVBA 4ZRPA 3SDQA 1AGMA 2DROA 3WIRA 3D3IA 1LTXB 3RX7A 3M7CA 4D4BA 3RX8A 3QPFA 3VXDA 4GTPB 1QBQB 1HZFA 2XWBB 1FT1B 1F9DA 2WYNA 1G87A 2Z07A 3H7LA 5DGQA 4M76A 4Q2BA 1KKTA 5M7YA 3DSXB 4GTSB 2JG0A 1F9OA 5JPMB 5JPNB 3K7XA 3OXUA 1IA6A 1FBWA 4JJJA 2AHFA 2ZBLA 1LD7B 3TF4A 1FP3A 1GXMA 2RGKA 4D94A 4FXKB 3A3VA 1CLCA 3S4AA 1X81B 1GAHA 1V5CA 4YCRA 3K11A 3SDVA 3ANKA 1H39A 1O1SB 4V1RA 3ANJA 3VW5A 3M7EA 2WY7A 4GTQB 3H2WA 1KFGA 4GTOB 4ZH1A 3D5SA 2GZ6A 1RQ5A 1H14A 4YDOB 5FO8B 1O79A 1X9DA 3SDRA 4GTTB 3P5PA 1O1TB 1R76A 3Q7AB 3M76A 5CZLA 5KKBA 4Z4JA 2QNOA 2WY8A 3DSTB 2EACA 1G9GA 1N4RB 1O1RB 2H6IB 1GHQA 3PZ2B 1TN7B 3QG0A 3QT3A 1LF6A 1S63B 1FO2A 3KQ4A 4FUSA 3E34B 4CJ1A 3QWTA 4AYPA 2V3NA 1UT9A 3QFYA 3M75A 1D8EB 1O6RA 2B4FA 4DOEA 2SQCA 3E32B 2VN7A 4AYOA 1TNUB 1SA5B 2PMVA 3CU7A 3HXCB 1TNZB 2DRRA 3P2CA 4WU0A 3M7LA 2EABA 2NOJA 2WIIB 4J5TA 1GA2A 3DPYB 4TF4A 1O5MB 3DSSB 1TNBB 4GTMB 4LNVA 2GOXA 2AHGA 1AYXA 1FCEA 1N95B 2D8LA 2P0VA 3M71A 3SFXB 5FOBB 2DRSA 2XFGA 2B39A 3C72B 3DSUB 4ZG8A 4WVCA 2V8IA 3S9VA 3M77A 4MU9A 1O6QA 3M73A 3Q78B 1DCEB 1W6JA 1QSJA 1UG9A 3WIWA 1JCRB 3WC3A 1SQCA 2VN4A 2A73B 3ACTA 2DRQA 2G02A 2XQWA 1ULVA 3CIHA 2GH4A 3W7TA 2F0YB 1TN8B 4ZH5A 3HXFB 1N4QB 2JJBA 3KLSA 2YIKA 4QT9A 1KRFA 2CQTA 2EADA 3DSWB 1V7XA 2ZZRA 1S64B 1JCQB 3RSYA 1XWTA 1FT2B 3E30B 3SQCA 1LF9A 3KSLB 2XWJB 3E37B 4AYRA 3W7UA 3QSPA 4TXTA 3OEDA 4KKJA 5MEHA 3Q73B 2BBCA 2V8KA 4CE7A 3SFYB 1FPPB 2OKXA 1GXOA 3PZ1B 5GZKA 1WU5A 1GSZA 1H3BA 4EHMB 3W7SA 3E6UA 3SAEA 2RI9A 4V1SA 2JF4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D8E B;  4D4D A;  1O6R A;  3RJ3 A;  1NL4 B;  4GTP B;  1QBQ B;  2SQC A;  1HZF A;  3E32 B;  2ZIS B;  2BB5 A;  2XWB B;  1TNY B;  4MBG B;  1FT1 B;  1TNU B;  1SA5 B;  1SA4 B;  2PMV A;  4BOK A;  1MZC B;  1TNO B;  3CU7 A;  3HXC B;  1TNZ B;  4M76 A;  3HXD B;  1W6K A;  3PZ3 B;  2NOJ A;  2WII B;  3Q79 B;  3DPY B;  3KSQ B;  1H36 A;  3DSX B;  1O5M B;  1QQF A;  1JCS B;  3DSS B;  4GTS B;  1TNB B;  1H3C A;  4GTM B;  4LNB B;  3G6J B;  4LNV A;  5JPN B;  5JPM B;  2GOX A;  2PN5 A;  3K7X A;  3OXU A;  1N95 B;  1LD7 B;  3SFX B;  1GXM A;  5FOB B;  4ZRQ A;  4LNG B;  3PZ4 B;  2H6G B;  4D94 A;  4FXK B;  2B39 A;  3C72 B;  3DSU B;  1X81 B;  2V8I A;  2V3P A;  2H6H B;  1TN6 B;  4MU9 A;  1H39 A;  1O1S B;  2I07 B;  1O6Q A;  4V1R A;  1H35 A;  3Q78 B;  2WY7 A;  1DCE B;  3E33 B;  1W6J A;  4GTQ B;  5FO9 B;  1QSJ A;  4GTO B;  4ZH1 A;  3D5S A;  4FXG B;  1JCR B;  4C1S A;  1SQC A;  3HXB B;  3DSV B;  5FO7 B;  2A73 B;  2G0D A;  4YDO B;  1UMP A;  1NI1 B;  3EUV B;  5FO8 B;  2G02 A;  3D5R A;  2XQW A;  1KZO B;  1N9A B;  1O79 A;  4GTV B;  3Q75 B;  4BOJ A;  2F0Y B;  2IEJ B;  4GTT B;  1TN8 B;  1KZP B;  2BB6 A;  2V8J A;  1C3D A;  1H3A A;  1H37 A;  3HXF B;  1N4Q B;  2ZIR B;  1O1T B;  1LD8 B;  1N4S B;  1R76 A;  3KLS A;  4YDE B;  3Q7A B;  3DSW B;  3EU5 B;  1S64 B;  4ONT A;  1JCQ B;  4D4A A;  2H6F B;  1FT2 B;  2WIN B;  3DRA B;  3E30 B;  3SQC A;  2WY8 A;  3DST B;  3HXE B;  3KSL B;  1N4P B;  2R2L B;  4D4C A;  2XWJ B;  1N4R B;  5AGD A;  1O1R B;  3E37 B;  2H6I B;  1O6H A;  2BED B;  1GHQ A;  3PZ2 B;  1TN7 B;  1S63 B;  3OED A;  4GTR B;  1N94 B;  4KKJ A;  3Q73 B;  3KQ4 A;  1D8D B;  2BBC A;  2V8K A;  4ZRP A;  3SFY B;  1FPP B;  1GXO A;  3E34 B;  3PZ1 B;  1LTX B;  1GSZ A;  1H3B A;  4EHM B;  4KKI A;  4D4B A;  2V3N A;  4L9P B;  1GXN A;  4V1S A;  3Q7F B; 
#chains in the Genus database with same CATH topology
 4AYQ A;  1NL4 B;  3M78 A;  1NC5 A;  3RRS A;  1HMW A;  1WZZ A;  3AFJ A;  4KTR A;  1OJO A;  2ZIS B;  2BB5 A;  1TNY B;  3W5N A;  4L0G A;  4F13 A;  1SA4 B;  2WDA A;  1N24 A;  1LOH A;  3HXD B;  1GAI A;  3PZ3 B;  3M74 A;  1KSC A;  3Q79 B;  3KSQ B;  1H36 A;  3QXF A;  1QQF A;  1H54 A;  1JCS B;  1H3C A;  4LNB B;  2FUQ A;  3G6J B;  3PMM A;  3SDT A;  1TF4 A;  2PN5 A;  3S4D A;  3ANI A;  4ZRQ A;  4LNG B;  3PZ4 B;  3NNB A;  1LXM A;  3RX5 A;  1RWH A;  2H6H B;  1TN6 B;  5M7I A;  3WKG A;  1KWF A;  3QXQ A;  1L2A A;  3SDU A;  4FXG B;  3EZ8 A;  3E7J A;  1KS8 A;  4KTP A;  4C1S A;  1VD5 A;  1K72 A;  3HXB B;  3DSV B;  5FO7 B;  2CQS A;  2G0D A;  4L6X A;  1UMP A;  3EUV B;  4EL8 A;  3D5R A;  3E73 A;  1KZO B;  4WVA A;  1CB8 A;  3GT5 A;  3QT9 A;  4GTV B;  2A8Z A;  3WKI A;  1CEM A;  1IA7 A;  2BB6 A;  3X17 A;  1C3D A;  1I8Q A;  5C05 A;  2ZIR B;  3M00 A;  3EU5 B;  3QFZ A;  4ONT A;  1QAZ A;  4GL3 A;  5E2J A;  3QDE A;  3WIQ A;  2FBA A;  2R2L B;  5CD2 A;  5AGD A;  4NEI A;  3NFV A;  3GZK A;  3W7X A;  1O6H A;  2BED B;  3ACS A;  5CA3 A;  3M7B A;  4LIX A;  1DL2 A;  5EAU A;  1N7N A;  1W3Y A;  5GY3 A;  4OJZ A;  1H12 A;  4KKI A;  1HX9 A;  4E1Y A;  2FUT A;  4L9P B;  1N7R A;  1GXN A;  3Q7F B;  4D4D A;  3RJ3 A;  1N1Z A;  3S4B A;  2ONG A;  5ILY A;  1FBO A;  4XUV A;  4MBG B;  1KSD A;  4BOK A;  1MZC B;  1TNO B;  4DOD A;  1X1H A;  2J5C A;  1W6K A;  3S4C A;  1N7O A;  1FMI A;  3W7W A;  3EQA A;  2Q1F A;  2RI8 A;  1DOG A;  1WU4 A;  3PYB A;  1X1I A;  5JMD A;  1XWQ A;  1FAE A;  1XW2 A;  5GW7 A;  4FNV A;  5EAS A;  4Z4L A;  3W5M A;  1HCU A;  3H3K A;  2H6G B;  1JS4 A;  1V5D A;  5IK9 A;  5IL8 A;  2V3P A;  1H13 A;  2I07 B;  2FV0 A;  1H35 A;  1N1B A;  2FUZ A;  1IS9 A;  3WKF A;  2AFA A;  1WU6 A;  3ON6 A;  3E33 B;  1KRE A;  3T33 A;  5FO9 B;  3REN A;  1GLM A;  3PYA A;  1NXC A;  1G9J A;  4Q88 A;  2FV1 A;  3EU8 A;  2WCO A;  3GLY A;  1NI1 B;  4CJ0 A;  1L1Y A;  1N9A B;  2ONH A;  3Q75 B;  4BOJ A;  2IEJ B;  1KZP B;  3M01 A;  4GAX A;  2V8J A;  3M72 A;  1H3A A;  1H37 A;  3WUX A;  5IM1 A;  1V7V A;  3P5R A;  1LD8 B;  1N4S B;  1N20 A;  4YDE B;  1HXG A;  1G6I A;  3QRY A;  3WKH A;  1FO3 A;  5IKH A;  2NVP A;  1N23 A;  4OK4 A;  2F6D A;  4D4A A;  2H6F B;  2D5J A;  2WIN B;  3DRA B;  3HXE B;  1N4P B;  4D4C A;  2EAE A;  1J0M A;  1HN0 A;  3G4F A;  1J0N A;  1RWG A;  4GTR B;  1N94 B;  5DGR A;  1V7W A;  1D8D B;  4WVB A;  4ZRP A;  3SDQ A;  1AGM A;  2DRO A;  5ILK A;  3WIR A;  3D3I A;  1LTX B;  3RX7 A;  3M7C A;  4D4B A;  3G4D A;  3RX8 A;  1RWA A;  3QPF A;  2E24 A;  1HM2 A;  3VXD A;  4GTP B;  1QBQ B;  1HZF A;  1HV6 A;  5ILH A;  2BRV X;  2XWB B;  1FT1 B;  1F9D A;  2WYN A;  1G87 A;  2Z07 A;  3H7L A;  5ILJ A;  5DGQ A;  4M76 A;  4Q2B A;  1RWF A;  1KKT A;  3N0G A;  5M7Y A;  3DSX B;  4GTS B;  4OZW A;  1N21 A;  2JG0 A;  1F9O A;  5JPM B;  5JPN B;  3K7X A;  3OXU A;  1IA6 A;  1FBW A;  1OJM A;  2AHF A;  4JJJ A;  2ZBL A;  1LD7 B;  3TF4 A;  1FP3 A;  1GXM A;  2RGK A;  4OZV A;  4D94 A;  4FXK B;  3A3V A;  1CLC A;  3S4A A;  1X81 B;  1GAH A;  1V5C A;  4MMH A;  4YCR A;  3K11 A;  3SDV A;  3ANK A;  4F10 A;  1H39 A;  1O1S B;  4V1R A;  3ANJ A;  3VW5 A;  3M7E A;  2WY7 A;  1N7Q A;  4GTQ B;  3VSM A;  3H2W A;  1KFG A;  5ILZ A;  4GTO B;  4ZH1 A;  3D5S A;  4DI5 A;  2E22 A;  2GZ6 A;  1RQ5 A;  1H14 A;  4YDO B;  5FO8 B;  4MMI A;  1O79 A;  1X9D A;  3SDR A;  4GTT B;  5IK0 A;  2X03 A;  3P5P A;  1O1T B;  4RNQ A;  1R76 A;  3Q7A B;  3M76 A;  3AFL A;  5CZL A;  5KKB A;  3VSN A;  4Z4J A;  2QNO A;  2WY8 A;  3DST B;  2EAC A;  1G9G A;  1N4R B;  1O1R B;  2H6I B;  1OJP A;  1GHQ A;  5JMF A;  3PZ2 B;  1TN7 B;  3QG0 A;  3QT3 A;  1LF6 A;  1S63 B;  1FO2 A;  3KQ4 A;  4FUS A;  1N22 A;  1HXC A;  3E34 B;  1N7P A;  4CJ1 A;  3QWT A;  4AYP A;  2V3N A;  1HXA A;  1LXK A;  1UT9 A;  3A0O A;  3LZ9 A;  3QFY A;  3M75 A;  5ILD A;  1D8E B;  1O6R A;  1F1S A;  2B4F A;  1F9G A;  4DOE A;  2SQC A;  3E32 B;  2VN7 A;  4AYO A;  1TNU B;  1SA5 B;  3M02 A;  2PMV A;  3CU7 A;  3HXC B;  1TNZ B;  2DRR A;  3P2C A;  4WU0 A;  3M7L A;  2EAB A;  2NOJ A;  2WII B;  4J5T A;  1GA2 A;  3DPY B;  1RW9 A;  4TF4 A;  5DHK A;  1O5M B;  3DSS B;  5IKA A;  1TNB B;  4GTM B;  4LNV A;  2GOX A;  2AHG A;  3E80 A;  5DHI A;  1AYX A;  1FCE A;  1N95 B;  2D8L A;  2P0V A;  3M71 A;  3SFX B;  5FOB B;  2DRS A;  2XFG A;  2B39 A;  3C72 B;  3DSU B;  2BRP A;  4ZG8 A;  4WVC A;  2V8I A;  3S9V A;  3M77 A;  4MU9 A;  4OK2 A;  5IK6 A;  1O6Q A;  3M73 A;  3Q78 B;  1DCE B;  5ILI A;  1W6J A;  1QSJ A;  1UG9 A;  3WIW A;  1JCR B;  3WC3 A;  1SQC A;  2VN4 A;  2A73 B;  3ACT A;  2DRQ A;  2G02 A;  2XQW A;  1ULV A;  3CIH A;  2GH4 A;  3W7T A;  2F0Y B;  1TN8 B;  4FJQ A;  4ZH5 A;  3HXF B;  1N4Q B;  1OJN A;  2JJB A;  3KLS A;  2YIK A;  4QT9 A;  1KRF A;  2CQT A;  2EAD A;  3DSW B;  1V7X A;  2ZZR A;  1S64 B;  1JCQ B;  3RSY A;  1XWT A;  1FT2 B;  3E30 B;  3SQC A;  5EAT A;  1LF9 A;  3KSL B;  5IL3 A;  2XWJ B;  1C82 A;  2BRW A;  3E37 B;  1HMU A;  4AYR A;  3W7U A;  3QSP A;  4TXT A;  3OED A;  1X1J A;  4KKJ A;  5MEH A;  3Q73 B;  2BBC A;  2V8K A;  3N0F A;  4CE7 A;  3SFY B;  1FPP B;  2OKX A;  1GXO A;  3PZ1 B;  5GZK A;  1WU5 A;  1GSZ A;  1H3B A;  4EHM B;  1HM3 A;  3W7S A;  1EGU A;  1RWC A;  3E6U A;  3SAE A;  2RI9 A;  4V1S A;  2JF4 A; 
#chains in the Genus database with same CATH homology
 4AYQ A;  1NL4 B;  3M78 A;  1NC5 A;  3RRS A;  1WZZ A;  3AFJ A;  4KTR A;  2ZIS B;  2BB5 A;  1TNY B;  3W5N A;  4L0G A;  1SA4 B;  3HXD B;  1GAI A;  3PZ3 B;  3M74 A;  1KSC A;  3Q79 B;  3KSQ B;  1H36 A;  3QXF A;  1QQF A;  1H54 A;  1JCS B;  1H3C A;  4LNB B;  3PMM A;  3G6J B;  3SDT A;  1TF4 A;  2PN5 A;  3S4D A;  3ANI A;  4ZRQ A;  4LNG B;  3PZ4 B;  3RX5 A;  2H6H B;  1TN6 B;  5M7I A;  3WKG A;  1KWF A;  3QXQ A;  1L2A A;  3SDU A;  4FXG B;  3EZ8 A;  1KS8 A;  4KTP A;  4C1S A;  1VD5 A;  1K72 A;  3HXB B;  3DSV B;  5FO7 B;  2CQS A;  2G0D A;  4L6X A;  1UMP A;  3EUV B;  4EL8 A;  3D5R A;  3E73 A;  1KZO B;  4WVA A;  3GT5 A;  3QT9 A;  4GTV B;  2A8Z A;  3WKI A;  1CEM A;  1IA7 A;  2BB6 A;  3X17 A;  1C3D A;  2ZIR B;  3EU5 B;  3QFZ A;  4ONT A;  4GL3 A;  5E2J A;  3QDE A;  3WIQ A;  2FBA A;  2R2L B;  5CD2 A;  5AGD A;  3GZK A;  3W7X A;  1O6H A;  2BED B;  3ACS A;  5CA3 A;  3M7B A;  4LIX A;  1DL2 A;  5GY3 A;  1H12 A;  4KKI A;  4L9P B;  1GXN A;  3Q7F B;  4D4D A;  3RJ3 A;  3S4B A;  1FBO A;  4XUV A;  4MBG B;  1KSD A;  4BOK A;  1MZC B;  1TNO B;  4DOD A;  1W6K A;  3S4C A;  1FMI A;  3W7W A;  3EQA A;  2RI8 A;  1DOG A;  1WU4 A;  3PYB A;  1XWQ A;  1FAE A;  1XW2 A;  5GW7 A;  4Z4L A;  3W5M A;  1HCU A;  3H3K A;  2H6G B;  1JS4 A;  1V5D A;  2V3P A;  1H13 A;  2I07 B;  2FV0 A;  1H35 A;  2FUZ A;  3WKF A;  1IS9 A;  2AFA A;  1WU6 A;  3ON6 A;  3E33 B;  1KRE A;  3T33 A;  5FO9 B;  3REN A;  1GLM A;  3PYA A;  1NXC A;  1G9J A;  4Q88 A;  2FV1 A;  3EU8 A;  3GLY A;  1NI1 B;  4CJ0 A;  1L1Y A;  1N9A B;  3Q75 B;  4BOJ A;  2IEJ B;  1KZP B;  2V8J A;  3M72 A;  1H3A A;  1H37 A;  3WUX A;  1V7V A;  3P5R A;  1LD8 B;  1N4S B;  4YDE B;  3QRY A;  1G6I A;  3WKH A;  1FO3 A;  2NVP A;  2F6D A;  4D4A A;  2H6F B;  2D5J A;  2WIN B;  3DRA B;  3HXE B;  1N4P B;  4D4C A;  2EAE A;  4GTR B;  1N94 B;  5DGR A;  1V7W A;  1D8D B;  4WVB A;  4ZRP A;  3SDQ A;  1AGM A;  2DRO A;  3WIR A;  3D3I A;  1LTX B;  3RX7 A;  3M7C A;  4D4B A;  3RX8 A;  3QPF A;  3VXD A;  4GTP B;  1QBQ B;  1HZF A;  2XWB B;  1FT1 B;  1F9D A;  2WYN A;  1G87 A;  2Z07 A;  3H7L A;  5DGQ A;  4M76 A;  4Q2B A;  1KKT A;  5M7Y A;  3DSX B;  4GTS B;  2JG0 A;  1F9O A;  5JPM B;  5JPN B;  3K7X A;  3OXU A;  1IA6 A;  1FBW A;  4JJJ A;  2AHF A;  2ZBL A;  1LD7 B;  3TF4 A;  1FP3 A;  1GXM A;  2RGK A;  4D94 A;  4FXK B;  3A3V A;  1CLC A;  3S4A A;  1X81 B;  1GAH A;  1V5C A;  4YCR A;  3K11 A;  3SDV A;  3ANK A;  1H39 A;  1O1S B;  4V1R A;  3ANJ A;  3VW5 A;  3M7E A;  2WY7 A;  4GTQ B;  3H2W A;  1KFG A;  4GTO B;  4ZH1 A;  3D5S A;  2GZ6 A;  1RQ5 A;  1H14 A;  4YDO B;  5FO8 B;  1O79 A;  1X9D A;  3SDR A;  4GTT B;  3P5P A;  1O1T B;  1R76 A;  3Q7A B;  3M76 A;  5CZL A;  5KKB A;  4Z4J A;  2QNO A;  2WY8 A;  3DST B;  2EAC A;  1G9G A;  1N4R B;  1O1R B;  2H6I B;  1GHQ A;  3PZ2 B;  1TN7 B;  3QG0 A;  3QT3 A;  1LF6 A;  1S63 B;  1FO2 A;  3KQ4 A;  4FUS A;  3E34 B;  4CJ1 A;  3QWT A;  4AYP A;  2V3N A;  1UT9 A;  3QFY A;  3M75 A;  1D8E B;  1O6R A;  2B4F A;  4DOE A;  2SQC A;  3E32 B;  2VN7 A;  4AYO A;  1TNU B;  1SA5 B;  2PMV A;  3CU7 A;  3HXC B;  1TNZ B;  2DRR A;  3P2C A;  4WU0 A;  3M7L A;  2EAB A;  2NOJ A;  2WII B;  4J5T A;  1GA2 A;  3DPY B;  4TF4 A;  1O5M B;  3DSS B;  1TNB B;  4GTM B;  4LNV A;  2GOX A;  2AHG A;  1AYX A;  1FCE A;  1N95 B;  2D8L A;  2P0V A;  3M71 A;  3SFX B;  5FOB B;  2DRS A;  2XFG A;  2B39 A;  3C72 B;  3DSU B;  4ZG8 A;  4WVC A;  2V8I A;  3S9V A;  3M77 A;  4MU9 A;  1O6Q A;  3M73 A;  3Q78 B;  1DCE B;  1W6J A;  1QSJ A;  1UG9 A;  3WIW A;  1JCR B;  3WC3 A;  1SQC A;  2VN4 A;  2A73 B;  3ACT A;  2DRQ A;  2G02 A;  2XQW A;  1ULV A;  3CIH A;  2GH4 A;  3W7T A;  2F0Y B;  1TN8 B;  4ZH5 A;  3HXF B;  1N4Q B;  2JJB A;  3KLS A;  2YIK A;  4QT9 A;  1KRF A;  2CQT A;  2EAD A;  3DSW B;  1V7X A;  2ZZR A;  1S64 B;  1JCQ B;  3RSY A;  1XWT A;  1FT2 B;  3E30 B;  3SQC A;  1LF9 A;  3KSL B;  2XWJ B;  3E37 B;  4AYR A;  3W7U A;  3QSP A;  4TXT A;  3OED A;  4KKJ A;  5MEH A;  3Q73 B;  2BBC A;  2V8K A;  4CE7 A;  3SFY B;  1FPP B;  2OKX A;  1GXO A;  3PZ1 B;  5GZK A;  1WU5 A;  1GSZ A;  1H3B A;  4EHM B;  3W7S A;  3E6U A;  3SAE A;  2RI9 A;  4V1S A;  2JF4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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