1JCRB

Crystal structure of rat protein farnesyltransferase complexed with the non-substrate tetrapeptide inhibitor cvfm and farnesyl diphosphate substrate
Total Genus 154
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
sequence length
407
structure length
407
Chain Sequence
PVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Rattus norvegicus
molecule keywords PROTEIN FARNESYLTRANSFERASE, ALPHA SUBUNIT
total genus 154
structure length 407
sequence length 407
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2001-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1jcrB00
4EHMB 4KKIA 4BOJA 1GXNA 1KZOB 1LD8B 1KZPB 3Q78B 2GOXA 2XWBB 1R76A 3Q7AB 5AGDA 3PZ4B 4KKJA 5FO7B 3C72B 4LNGB 2V3NA 1X81B 4V1RA 3KQ4A 1JCRB 3DSWB 1O1RB 1N4QB 1JCQB 4D94A 3SFYB 3HXFB 3KSLB 3PZ2B 1N4SB 1S64B 2WIIB 5JPMB 1D8EB 1O79A 2XWJB 2H6FB 1QQFA 1GSZA 3HXBB 2XQWA 1O5MB 4GTRB 4ZH1A 1DCEB 4C1SA 4MU9A 3E32B 1N94B 1TN6B 3CU7A 3HXEB 1TNBB 1H35A 5FOBB 3E37B 3HXCB 3Q7FB 1S63B 3D5SA 2I07B 1H36A 1SA5B 2A73B 2BBCA 4YDOB 4LNBB 2ZISB 3OXUA 1N4RB 4GTOB 1QSJA 3EU5B 3KSQB 3Q79B 2F0YB 1GXOA 1TNUB 1TNYB 4GTMB 1MZCB 1SQCA 1JCSB 3EUVB 1SA4B 2V8KA 3SFXB 1O1SB 1GHQA 4D4CA 2NOJA 4FXKB 4GTQB 4M76A 4ONTA 5FO8B 2SQCA 1LTXB 3DSUB 3RJ3A 3KLSA 2ZIRB 4GTTB 4D4BA 2V8IA 3E30B 1NL4B 2WY8A 4YDEB 1NI1B 3DRAB 3G6JB 2G02A 1C3DA 4FXGB 5JPNB 3DSXB 2H6IB 1H39A 2IEJB 1GXMA 1H3BA 1FT2B 1FPPB 1O1TB 2B39A 2PMVA 3Q75B 5FO9B 2G0DA 1TN7B 2V8JA 3OEDA 4ZRQA 1H3CA 1N9AB 3E34B 1N4PB 1TN8B 3Q73B 4D4DA 3SQCA 4ZRPA 4LNVA 1W6KA 3PZ3B 3D5RA 3K7XA 2H6HB 2PN5A 1TNZB 2WY7A 1HZFA 1W6JA 1UMPA 2BEDB 3DPYB 1LD7B 1O6HA 1TNOB 4GTPB 4GTSB 3DSSB 3DSVB 4BOKA 2H6GB 3DSTB 3E33B 1H37A 2WINB 1FT1B 2BB6A 1O6RA 2V3PA 1QBQB 1N95B 1D8DB 2R2LB 4D4AA 4L9PB 3PZ1B 1O6QA 4V1SA 3HXDB 2BB5A 4MBGB 4GTVB 1H3AA
chains in the Genus database with same CATH superfamily
3N0FA 3H2WA 3W7XA 1X1IA 4OZWA 2GOXA 5AGDA 1R76A 3Q7AB 3PZ4B 4KKJA 5ILKA 1LF6A 3ANIA 2OKXA 4V1RA 5MEHA 2JF4A 1HXGA 1N7PA 2X03A 3N0GA 1N4QB 1H13A 5JMFA 4D94A 3SFYB 3E80A 3PZ2B 1N4SB 3EQAA 5JPMB 3VW5A 2VN7A 2XWJB 1AYXA 3A3VA 3AFLA 1QQFA 3HXBB 3M7BA 4GAXA 3WKIA 4YCRA 1NC5A 4OJZA 1O5MB 4GTRB 1DCEB 1N23A 2FUTA 5DHIA 1OJOA 1H35A 4WVBA 3QT9A 1HM3A 3ACTA 3HXCB 3Q7FB 2I07B 1FO2A 1KS8A 1DL2A 1FBWA 1N4RB 1N20A 4GTOB 1QSJA 4L0GA 4WVCA 3KSQB 1GXOA 1V7WA 2F0YB 1SA4B 3M7CA 3SDUA 4WU0A 1O1SB 4M76A 1RWHA 2JG0A 4ONTA 4AYQA 3DSUB 3KLSA 1HV6A 3E30B 1F9GA 2WY8A 4YDEB 1X1JA 3M02A 3QSPA 3DRAB 3G6JB 5JPNB 5DHKA 1V5DA 1H39A 1CB8A 1FO3A 1GXMA 2F6DA 1FPPB 2FUQA 5FO9B 2G0DA 4NEIA 1H3CA 2WYNA 2D5JA 1LOHA 1CEMA 1N4PB 1N1ZA 2DRSA 5CA3A 1N7QA 3G4FA 4TXTA 3PZ3B 2Z07A 4WVAA 1FBOA 5C05A 1J0MA 2FV0A 2ONHA 1UMPA 2BEDB 1LD7B 1O6HA 1TNOB 1VD5A 2VN4A 1HN0A 4GTPB 3WIQA 2EACA 4BOKA 3QDEA 1X9DA 1QBQB 1F9DA 5ILYA 1D8DB 4L9PB 4ZH5A 2BB5A 4J5TA 4XUVA 5EAUA 5ILZA 1QAZA 3QXFA 5ILDA 3PMMA 3WKFA 2XWBB 1LXMA 3W7UA 5FO7B 2GZ6A 1WU5A 2V3NA 1X81B 3PYAA 3W7SA 4OZVA 1O1RB 3D3IA 3WUXA 1H54A 2RI9A 1J0NA 1W3YA 2WIIB 1N21A 5IKHA 1O79A 1XWQA 3W7TA 2XQWA 3NNBA 2FV1A 1RWCA 1WZZA 1G9GA 3S4AA 5CD2A 5FOBB 3VSMA 3E37B 4Z4LA 4F13A 3RENA 1L2AA 1SA5B 2A73B 2CQSA 3M77A 4YDOB 3NFVA 3EU5B 3QXQA 1MZCB 2E22A 1JCSB 3EUVB 2ZBLA 1KWFA 1F1SA 4TF4A 1NL4B 4FJQA 1KFGA 4DI5A 4FXGB 1IA6A 1FMIA 1TN7B 2V8JA 3S4CA 5IKAA 1F9OA 3PYBA 4KTRA 2EADA 1TN8B 3W5MA 4ZRPA 3M76A 2XFGA 3QWTA 1RQ5A 1W6KA 3D5RA 1X1HA 2BRPA 3K7XA 1TNZB 4KTPA 1XWTA 2WY7A 3QT3A 4ZG8A 2GH4A 1LXKA 3DPYB 1UG9A 3W5NA 5GZKA 3DSSB 4FUSA 5KKBA 2BB6A 1O6RA 2B4FA 1KRFA 3RX8A 1O6QA 3HXDB 1KKTA 5DGQA 5IL8A 4AYOA 3GZKA 3T33A 1GLMA 4MMIA 3RRSA 5IK9A 1XW2A 3CIHA 3QFZA 3VSNA 2QNOA 3S4BA 1UT9A 3EU8A 3DSWB 3KQ4A 3QPFA 2A8ZA 1FAEA 5EATA 5IL3A 1K72A 1JCQB 3TF4A 3KSLB 1S64B 1D8EB 1FP3A 4OK4A 2JJBA 1LF9A 2H6FB 1GSZA 3M7LA 4MU9A 3M75A 1V7XA 1N94B 1TN6B 4DODA 1WU6A 3S9VA 3S4DA 4MMHA 3M78A 1RWAA 2BRVX 4AYPA 3D5SA 5ILJA 2YIKA 3E7JA 5GW7A 1GA2A 4EL8A 2AHGA 3WKGA 5ILIA 4GTMB 1TNUB 3SDVA 1G9JA 1ULVA 1SQCA 1G87A 1N22A 3VXDA 4CJ1A 1V5CA 3SFXB 3SDRA 4D4CA 2J5CA 3EZ8A 4GTQB 1HXCA 4CJ0A 5E2JA 5FO8B 5GY3A 3G4DA 3GT5A 4GTTB 3M01A 1HM2A 1WU4A 3M74A 4Z4JA 1N7RA 2H6IB 3QRYA 3QFYA 2IEJB 3RX7A 1H3BA 2B39A 1O1TB 3Q75B 2PMVA 3QG0A 1H14A 3ACSA 3ON6A 4ZRQA 3SDQA 4DOEA 1EGUA 3Q73B 4D4DA 3SDTA 3SQCA 1GAHA 2BRWA 2AHFA 3P5RA 1N1BA 2P0VA 2H6HB 2PN5A 4FNVA 3W7WA 1W6JA 3P5PA 3RSYA 3M00A 1DOGA 4AYRA 3K11A 2WDAA 1OJPA 1TF4A 2RI8A 2WCOA 5IM1A 4QT9A 1OJNA 3DSVB 2H6GB 1RWFA 3WKHA 3PZ1B 1H12A 2ZZRA 4LIXA 2SQCA 1H3AA 2RGKA 4EHMB 1KREA 4KKIA 4BOJA 1GXNA 1KZOB 3H3KA 1LD8B 5EASA 1KZPB 3Q78B 4RNQA 3P2CA 2DROA 3C72B 4CE7A 4LNGB 2DRRA 5JMDA 3X17A 1JCRB 2DRQA 2FUZA 1N7OA 3HXFB 1AGMA 1RW9A 5ILHA 1N7NA 4F10A 2FBAA 1KSCA 2ONGA 1I8QA 1N24A 3WC3A 3A0OA 4ZH1A 4C1SA 1IA7A 1NXCA 5IK0A 3E32B 3CU7A 3HXEB 1TNBB 3M7EA 1S63B 1H36A 1JS4A 2BBCA 4LNBB 2Q1FA 2ZISB 3OXUA 4OK2A 1HX9A 1L1YA 3Q79B 1TNYB 4L6XA 3M73A 2V8KA 1GHQA 3M72A 2NOJA 4FXKB 1LTXB 1KSDA 3RJ3A 1RWGA 2ZIRB 4D4BA 2V8IA 1HMWA 1NI1B 1CLCA 1G6IA 2G02A 1C3DA 1HXAA 2CQTA 3GLYA 1OJMA 3DSXB 2NVPA 4Q2BA 3WIRA 1GAIA 2EAEA 1FT2B 2D8LA 3OEDA 5DGRA 1N9AB 3E34B 2AFAA 3M71A 3ANKA 1FCEA 4LNVA 3WIWA 3SAEA 4GL3A 2E24A 3LZ9A 4JJJA 1IS9A 5M7YA 5IK6A 1HZFA 3E6UA 1V7VA 4Q88A 1HCUA 2EABA 4GTSB 5CZLA 3DSTB 3AFJA 3E33B 1H37A 2WINB 1FT1B 2V3PA 1HMUA 5M7IA 1N95B 3ANJA 2R2LB 4D4AA 4V1SA 3RX5A 3E73A 4E1YA 1C82A 4MBGB 4GTVB 3H7LA
chains in the Genus database with same CATH topology
3H2WA 3W7XA 2GOXA 5AGDA 1R76A 3Q7AB 3PZ4B 4KKJA 1LF6A 3ANIA 2OKXA 4V1RA 5MEHA 2JF4A 1N4QB 1H13A 4D94A 3SFYB 3PZ2B 1N4SB 3EQAA 5JPMB 3VW5A 2VN7A 2XWJB 1AYXA 3A3VA 1QQFA 3HXBB 3M7BA 3WKIA 4YCRA 1NC5A 1O5MB 4GTRB 1DCEB 1H35A 4WVBA 3QT9A 3ACTA 3HXCB 3Q7FB 2I07B 1FO2A 1KS8A 1DL2A 1FBWA 1N4RB 4GTOB 1QSJA 4L0GA 4WVCA 3KSQB 1GXOA 1V7WA 2F0YB 1SA4B 3M7CA 3SDUA 4WU0A 1O1SB 4M76A 2JG0A 4ONTA 4AYQA 3DSUB 3KLSA 3E30B 2WY8A 4YDEB 3QSPA 3DRAB 3G6JB 5JPNB 1V5DA 1H39A 1GXMA 1FO3A 2F6DA 1FPPB 5FO9B 2G0DA 1H3CA 2WYNA 2D5JA 1CEMA 1N4PB 2DRSA 5CA3A 4TXTA 3PZ3B 2Z07A 4WVAA 1FBOA 2FV0A 1UMPA 2BEDB 1LD7B 1O6HA 1TNOB 1VD5A 2VN4A 4GTPB 3WIQA 2EACA 4BOKA 3QDEA 1X9DA 1QBQB 1F9DA 1D8DB 4L9PB 4ZH5A 2BB5A 4J5TA 4XUVA 3QXFA 3PMMA 3WKFA 2XWBB 3W7UA 5FO7B 2GZ6A 1WU5A 2V3NA 1X81B 3PYAA 3W7SA 1O1RB 3D3IA 3WUXA 1H54A 2RI9A 2WIIB 1O79A 1XWQA 3W7TA 2XQWA 2FV1A 1WZZA 1G9GA 3S4AA 5CD2A 5FOBB 3E37B 4Z4LA 3RENA 1L2AA 1SA5B 2A73B 2CQSA 3M77A 4YDOB 3EU5B 3QXQA 1MZCB 1JCSB 3EUVB 2ZBLA 1KWFA 4TF4A 1NL4B 1KFGA 4FXGB 1IA6A 1FMIA 1TN7B 2V8JA 3S4CA 1F9OA 3PYBA 4KTRA 2EADA 1TN8B 3W5MA 4ZRPA 3M76A 2XFGA 3QWTA 1RQ5A 1W6KA 3D5RA 3K7XA 1TNZB 4KTPA 1XWTA 2WY7A 3QT3A 4ZG8A 2GH4A 3DPYB 1UG9A 3W5NA 5GZKA 3DSSB 4FUSA 5KKBA 2BB6A 1O6RA 2B4FA 1KRFA 3RX8A 1O6QA 3HXDB 1KKTA 5DGQA 4AYOA 3GZKA 3T33A 1GLMA 3RRSA 1XW2A 3CIHA 3QFZA 2QNOA 3S4BA 1UT9A 3EU8A 3DSWB 3KQ4A 3QPFA 2A8ZA 1FAEA 1K72A 1JCQB 3TF4A 3KSLB 1S64B 1D8EB 1FP3A 2JJBA 1LF9A 2H6FB 1GSZA 3M7LA 4MU9A 3M75A 1V7XA 1N94B 1TN6B 4DODA 1WU6A 3S9VA 3S4DA 3M78A 4AYPA 3D5SA 2YIKA 5GW7A 1GA2A 4EL8A 2AHGA 3WKGA 4GTMB 1TNUB 3SDVA 1G9JA 1ULVA 1SQCA 1G87A 3VXDA 4CJ1A 1V5CA 3SFXB 3SDRA 4D4CA 3EZ8A 4GTQB 4CJ0A 5E2JA 5FO8B 5GY3A 3GT5A 4GTTB 1WU4A 3M74A 4Z4JA 2H6IB 3QRYA 3QFYA 3RX7A 2IEJB 1H3BA 2B39A 1O1TB 3Q75B 2PMVA 3QG0A 1H14A 3ACSA 3ON6A 4ZRQA 3SDQA 4DOEA 3Q73B 4D4DA 3SDTA 3SQCA 1GAHA 2AHFA 3P5RA 2P0VA 2H6HB 2PN5A 3W7WA 1W6JA 3P5PA 3RSYA 1DOGA 4AYRA 3K11A 1TF4A 2RI8A 4QT9A 3DSVB 2H6GB 3WKHA 3PZ1B 1H12A 2ZZRA 4LIXA 2SQCA 1H3AA 2RGKA 4EHMB 1KREA 4KKIA 4BOJA 1GXNA 1KZOB 3H3KA 1LD8B 1KZPB 3Q78B 3P2CA 2DROA 3C72B 4CE7A 4LNGB 2DRRA 3X17A 1JCRB 2DRQA 2FUZA 3HXFB 1AGMA 2FBAA 1KSCA 3WC3A 4ZH1A 4C1SA 1IA7A 1NXCA 3E32B 3CU7A 3HXEB 1TNBB 3M7EA 1S63B 1H36A 1JS4A 2BBCA 4LNBB 2ZISB 3OXUA 1L1YA 3Q79B 1TNYB 4L6XA 3M73A 2V8KA 1GHQA 3M72A 2NOJA 4FXKB 1LTXB 1KSDA 3RJ3A 2ZIRB 4D4BA 2V8IA 1NI1B 1CLCA 1G6IA 2G02A 1C3DA 2CQTA 3GLYA 2NVPA 3DSXB 3WIRA 4Q2BA 1GAIA 2EAEA 1FT2B 2D8LA 3OEDA 5DGRA 1N9AB 3E34B 2AFAA 3M71A 3ANKA 1FCEA 4LNVA 3WIWA 3SAEA 4GL3A 4JJJA 1IS9A 5M7YA 1HZFA 3E6UA 1V7VA 4Q88A 1HCUA 2EABA 4GTSB 5CZLA 3DSTB 3AFJA 3E33B 1H37A 2WINB 1FT1B 2V3PA 5M7IA 1N95B 3ANJA 2R2LB 4D4AA 4V1SA 3RX5A 3E73A 4MBGB 4GTVB 3H7LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EHM B;  4KKI A;  4BOJ A;  1GXN A;  1KZO B;  1LD8 B;  1KZP B;  3Q78 B;  2GOX A;  2XWB B;  1R76 A;  3Q7A B;  5AGD A;  3PZ4 B;  4KKJ A;  5FO7 B;  3C72 B;  4LNG B;  2V3N A;  1X81 B;  4V1R A;  3KQ4 A;  1JCR B;  3DSW B;  1O1R B;  1N4Q B;  1JCQ B;  4D94 A;  3SFY B;  3HXF B;  3KSL B;  3PZ2 B;  1N4S B;  1S64 B;  2WII B;  5JPM B;  1D8E B;  1O79 A;  2XWJ B;  2H6F B;  1QQF A;  1GSZ A;  3HXB B;  2XQW A;  1O5M B;  4GTR B;  4ZH1 A;  1DCE B;  4C1S A;  4MU9 A;  3E32 B;  1N94 B;  1TN6 B;  3CU7 A;  3HXE B;  1TNB B;  1H35 A;  5FOB B;  3E37 B;  3HXC B;  3Q7F B;  1S63 B;  3D5S A;  2I07 B;  1H36 A;  1SA5 B;  2A73 B;  2BBC A;  4YDO B;  4LNB B;  2ZIS B;  3OXU A;  1N4R B;  4GTO B;  1QSJ A;  3EU5 B;  3KSQ B;  3Q79 B;  2F0Y B;  1GXO A;  1TNU B;  1TNY B;  4GTM B;  1MZC B;  1SQC A;  1JCS B;  3EUV B;  1SA4 B;  2V8K A;  3SFX B;  1O1S B;  1GHQ A;  4D4C A;  2NOJ A;  4FXK B;  4GTQ B;  4M76 A;  4ONT A;  5FO8 B;  2SQC A;  1LTX B;  3DSU B;  3RJ3 A;  3KLS A;  2ZIR B;  4GTT B;  4D4B A;  2V8I A;  3E30 B;  1NL4 B;  2WY8 A;  4YDE B;  1NI1 B;  3DRA B;  3G6J B;  2G02 A;  1C3D A;  4FXG B;  5JPN B;  3DSX B;  2H6I B;  1H39 A;  2IEJ B;  1GXM A;  1H3B A;  1FT2 B;  1FPP B;  1O1T B;  2B39 A;  2PMV A;  3Q75 B;  5FO9 B;  2G0D A;  1TN7 B;  2V8J A;  3OED A;  4ZRQ A;  1H3C A;  1N9A B;  3E34 B;  1N4P B;  1TN8 B;  3Q73 B;  4D4D A;  3SQC A;  4ZRP A;  4LNV A;  1W6K A;  3PZ3 B;  3D5R A;  3K7X A;  2H6H B;  2PN5 A;  1TNZ B;  2WY7 A;  1HZF A;  1W6J A;  1UMP A;  2BED B;  3DPY B;  1LD7 B;  1O6H A;  1TNO B;  4GTP B;  4GTS B;  3DSS B;  3DSV B;  4BOK A;  2H6G B;  3DST B;  3E33 B;  1H37 A;  2WIN B;  1FT1 B;  2BB6 A;  1O6R A;  2V3P A;  1QBQ B;  1N95 B;  1D8D B;  2R2L B;  4D4A A;  4L9P B;  3PZ1 B;  1O6Q A;  4V1S A;  3HXD B;  2BB5 A;  4MBG B;  4GTV B;  1H3A A; 
#chains in the Genus database with same CATH topology
 3N0F A;  3H2W A;  3W7X A;  1X1I A;  4OZW A;  2GOX A;  5AGD A;  1R76 A;  3Q7A B;  3PZ4 B;  4KKJ A;  5ILK A;  1LF6 A;  3ANI A;  2OKX A;  4V1R A;  5MEH A;  2JF4 A;  1HXG A;  1N7P A;  2X03 A;  3N0G A;  1N4Q B;  1H13 A;  5JMF A;  4D94 A;  3SFY B;  3E80 A;  3PZ2 B;  1N4S B;  3EQA A;  5JPM B;  3VW5 A;  2VN7 A;  2XWJ B;  1AYX A;  3A3V A;  3AFL A;  1QQF A;  3HXB B;  3M7B A;  4GAX A;  3WKI A;  4YCR A;  1NC5 A;  4OJZ A;  1O5M B;  4GTR B;  1DCE B;  1N23 A;  2FUT A;  5DHI A;  1OJO A;  1H35 A;  4WVB A;  3QT9 A;  1HM3 A;  3ACT A;  3HXC B;  3Q7F B;  2I07 B;  1FO2 A;  1KS8 A;  1DL2 A;  1FBW A;  1N4R B;  1N20 A;  4GTO B;  1QSJ A;  4L0G A;  4WVC A;  3KSQ B;  1GXO A;  1V7W A;  2F0Y B;  1SA4 B;  3M7C A;  3SDU A;  4WU0 A;  1O1S B;  4M76 A;  1RWH A;  2JG0 A;  4ONT A;  4AYQ A;  3DSU B;  3KLS A;  1HV6 A;  3E30 B;  1F9G A;  2WY8 A;  4YDE B;  1X1J A;  3M02 A;  3QSP A;  3DRA B;  3G6J B;  5JPN B;  5DHK A;  1V5D A;  1H39 A;  1CB8 A;  1FO3 A;  1GXM A;  2F6D A;  1FPP B;  2FUQ A;  5FO9 B;  2G0D A;  4NEI A;  1H3C A;  2WYN A;  2D5J A;  1LOH A;  1CEM A;  1N4P B;  1N1Z A;  2DRS A;  5CA3 A;  1N7Q A;  3G4F A;  4TXT A;  3PZ3 B;  2Z07 A;  4WVA A;  1FBO A;  5C05 A;  1J0M A;  2FV0 A;  2ONH A;  1UMP A;  2BED B;  1LD7 B;  1O6H A;  1TNO B;  1VD5 A;  2VN4 A;  1HN0 A;  4GTP B;  3WIQ A;  2EAC A;  4BOK A;  3QDE A;  1X9D A;  1QBQ B;  1F9D A;  5ILY A;  1D8D B;  4L9P B;  4ZH5 A;  2BB5 A;  4J5T A;  4XUV A;  5EAU A;  5ILZ A;  1QAZ A;  3QXF A;  5ILD A;  3PMM A;  3WKF A;  2XWB B;  1LXM A;  3W7U A;  5FO7 B;  2GZ6 A;  1WU5 A;  2V3N A;  1X81 B;  3PYA A;  3W7S A;  4OZV A;  1O1R B;  3D3I A;  3WUX A;  1H54 A;  2RI9 A;  1J0N A;  1W3Y A;  2WII B;  1N21 A;  5IKH A;  1O79 A;  1XWQ A;  3W7T A;  2XQW A;  3NNB A;  2FV1 A;  1RWC A;  1WZZ A;  1G9G A;  3S4A A;  5CD2 A;  5FOB B;  3VSM A;  3E37 B;  4Z4L A;  4F13 A;  3REN A;  1L2A A;  1SA5 B;  2A73 B;  2CQS A;  3M77 A;  4YDO B;  3NFV A;  3EU5 B;  3QXQ A;  1MZC B;  2E22 A;  1JCS B;  3EUV B;  2ZBL A;  1KWF A;  1F1S A;  4TF4 A;  1NL4 B;  4FJQ A;  1KFG A;  4DI5 A;  4FXG B;  1IA6 A;  1FMI A;  1TN7 B;  2V8J A;  3S4C A;  5IKA A;  1F9O A;  3PYB A;  4KTR A;  2EAD A;  1TN8 B;  3W5M A;  4ZRP A;  3M76 A;  2XFG A;  3QWT A;  1RQ5 A;  1W6K A;  3D5R A;  1X1H A;  2BRP A;  3K7X A;  1TNZ B;  4KTP A;  1XWT A;  2WY7 A;  3QT3 A;  4ZG8 A;  2GH4 A;  1LXK A;  3DPY B;  1UG9 A;  3W5N A;  5GZK A;  3DSS B;  4FUS A;  5KKB A;  2BB6 A;  1O6R A;  2B4F A;  1KRF A;  3RX8 A;  1O6Q A;  3HXD B;  1KKT A;  5DGQ A;  5IL8 A;  4AYO A;  3GZK A;  3T33 A;  1GLM A;  4MMI A;  3RRS A;  5IK9 A;  1XW2 A;  3CIH A;  3QFZ A;  3VSN A;  2QNO A;  3S4B A;  1UT9 A;  3EU8 A;  3DSW B;  3KQ4 A;  3QPF A;  2A8Z A;  1FAE A;  5EAT A;  5IL3 A;  1K72 A;  1JCQ B;  3TF4 A;  3KSL B;  1S64 B;  1D8E B;  1FP3 A;  4OK4 A;  2JJB A;  1LF9 A;  2H6F B;  1GSZ A;  3M7L A;  4MU9 A;  3M75 A;  1V7X A;  1N94 B;  1TN6 B;  4DOD A;  1WU6 A;  3S9V A;  3S4D A;  4MMH A;  3M78 A;  1RWA A;  2BRV X;  4AYP A;  3D5S A;  5ILJ A;  2YIK A;  3E7J A;  5GW7 A;  1GA2 A;  4EL8 A;  2AHG A;  3WKG A;  5ILI A;  4GTM B;  1TNU B;  3SDV A;  1G9J A;  1ULV A;  1SQC A;  1G87 A;  1N22 A;  3VXD A;  4CJ1 A;  1V5C A;  3SFX B;  3SDR A;  4D4C A;  2J5C A;  3EZ8 A;  4GTQ B;  1HXC A;  4CJ0 A;  5E2J A;  5FO8 B;  5GY3 A;  3G4D A;  3GT5 A;  4GTT B;  3M01 A;  1HM2 A;  1WU4 A;  3M74 A;  4Z4J A;  1N7R A;  2H6I B;  3QRY A;  3QFY A;  2IEJ B;  3RX7 A;  1H3B A;  2B39 A;  1O1T B;  3Q75 B;  2PMV A;  3QG0 A;  1H14 A;  3ACS A;  3ON6 A;  4ZRQ A;  3SDQ A;  4DOE A;  1EGU A;  3Q73 B;  4D4D A;  3SDT A;  3SQC A;  1GAH A;  2BRW A;  2AHF A;  3P5R A;  1N1B A;  2P0V A;  2H6H B;  2PN5 A;  4FNV A;  3W7W A;  1W6J A;  3P5P A;  3RSY A;  3M00 A;  1DOG A;  4AYR A;  3K11 A;  2WDA A;  1OJP A;  1TF4 A;  2RI8 A;  2WCO A;  5IM1 A;  4QT9 A;  1OJN A;  3DSV B;  2H6G B;  1RWF A;  3WKH A;  3PZ1 B;  1H12 A;  2ZZR A;  4LIX A;  2SQC A;  1H3A A;  2RGK A;  4EHM B;  1KRE A;  4KKI A;  4BOJ A;  1GXN A;  1KZO B;  3H3K A;  1LD8 B;  5EAS A;  1KZP B;  3Q78 B;  4RNQ A;  3P2C A;  2DRO A;  3C72 B;  4CE7 A;  4LNG B;  2DRR A;  5JMD A;  3X17 A;  1JCR B;  2DRQ A;  2FUZ A;  1N7O A;  3HXF B;  1AGM A;  1RW9 A;  5ILH A;  1N7N A;  4F10 A;  2FBA A;  1KSC A;  2ONG A;  1I8Q A;  1N24 A;  3WC3 A;  3A0O A;  4ZH1 A;  4C1S A;  1IA7 A;  1NXC A;  5IK0 A;  3E32 B;  3CU7 A;  3HXE B;  1TNB B;  3M7E A;  1S63 B;  1H36 A;  1JS4 A;  2BBC A;  4LNB B;  2Q1F A;  2ZIS B;  3OXU A;  4OK2 A;  1HX9 A;  1L1Y A;  3Q79 B;  1TNY B;  4L6X A;  3M73 A;  2V8K A;  1GHQ A;  3M72 A;  2NOJ A;  4FXK B;  1LTX B;  1KSD A;  3RJ3 A;  1RWG A;  2ZIR B;  4D4B A;  2V8I A;  1HMW A;  1NI1 B;  1CLC A;  1G6I A;  2G02 A;  1C3D A;  1HXA A;  2CQT A;  3GLY A;  1OJM A;  3DSX B;  2NVP A;  4Q2B A;  3WIR A;  1GAI A;  2EAE A;  1FT2 B;  2D8L A;  3OED A;  5DGR A;  1N9A B;  3E34 B;  2AFA A;  3M71 A;  3ANK A;  1FCE A;  4LNV A;  3WIW A;  3SAE A;  4GL3 A;  2E24 A;  3LZ9 A;  4JJJ A;  1IS9 A;  5M7Y A;  5IK6 A;  1HZF A;  3E6U A;  1V7V A;  4Q88 A;  1HCU A;  2EAB A;  4GTS B;  5CZL A;  3DST B;  3AFJ A;  3E33 B;  1H37 A;  2WIN B;  1FT1 B;  2V3P A;  1HMU A;  5M7I A;  1N95 B;  3ANJ A;  2R2L B;  4D4A A;  4V1S A;  3RX5 A;  3E73 A;  4E1Y A;  1C82 A;  4MBG B;  4GTV B;  3H7L A; 
#chains in the Genus database with same CATH homology
 3H2W A;  3W7X A;  2GOX A;  5AGD A;  1R76 A;  3Q7A B;  3PZ4 B;  4KKJ A;  1LF6 A;  3ANI A;  2OKX A;  4V1R A;  5MEH A;  2JF4 A;  1N4Q B;  1H13 A;  4D94 A;  3SFY B;  3PZ2 B;  1N4S B;  3EQA A;  5JPM B;  3VW5 A;  2VN7 A;  2XWJ B;  1AYX A;  3A3V A;  1QQF A;  3HXB B;  3M7B A;  3WKI A;  4YCR A;  1NC5 A;  1O5M B;  4GTR B;  1DCE B;  1H35 A;  4WVB A;  3QT9 A;  3ACT A;  3HXC B;  3Q7F B;  2I07 B;  1FO2 A;  1KS8 A;  1DL2 A;  1FBW A;  1N4R B;  4GTO B;  1QSJ A;  4L0G A;  4WVC A;  3KSQ B;  1GXO A;  1V7W A;  2F0Y B;  1SA4 B;  3M7C A;  3SDU A;  4WU0 A;  1O1S B;  4M76 A;  2JG0 A;  4ONT A;  4AYQ A;  3DSU B;  3KLS A;  3E30 B;  2WY8 A;  4YDE B;  3QSP A;  3DRA B;  3G6J B;  5JPN B;  1V5D A;  1H39 A;  1GXM A;  1FO3 A;  2F6D A;  1FPP B;  5FO9 B;  2G0D A;  1H3C A;  2WYN A;  2D5J A;  1CEM A;  1N4P B;  2DRS A;  5CA3 A;  4TXT A;  3PZ3 B;  2Z07 A;  4WVA A;  1FBO A;  2FV0 A;  1UMP A;  2BED B;  1LD7 B;  1O6H A;  1TNO B;  1VD5 A;  2VN4 A;  4GTP B;  3WIQ A;  2EAC A;  4BOK A;  3QDE A;  1X9D A;  1QBQ B;  1F9D A;  1D8D B;  4L9P B;  4ZH5 A;  2BB5 A;  4J5T A;  4XUV A;  3QXF A;  3PMM A;  3WKF A;  2XWB B;  3W7U A;  5FO7 B;  2GZ6 A;  1WU5 A;  2V3N A;  1X81 B;  3PYA A;  3W7S A;  1O1R B;  3D3I A;  3WUX A;  1H54 A;  2RI9 A;  2WII B;  1O79 A;  1XWQ A;  3W7T A;  2XQW A;  2FV1 A;  1WZZ A;  1G9G A;  3S4A A;  5CD2 A;  5FOB B;  3E37 B;  4Z4L A;  3REN A;  1L2A A;  1SA5 B;  2A73 B;  2CQS A;  3M77 A;  4YDO B;  3EU5 B;  3QXQ A;  1MZC B;  1JCS B;  3EUV B;  2ZBL A;  1KWF A;  4TF4 A;  1NL4 B;  1KFG A;  4FXG B;  1IA6 A;  1FMI A;  1TN7 B;  2V8J A;  3S4C A;  1F9O A;  3PYB A;  4KTR A;  2EAD A;  1TN8 B;  3W5M A;  4ZRP A;  3M76 A;  2XFG A;  3QWT A;  1RQ5 A;  1W6K A;  3D5R A;  3K7X A;  1TNZ B;  4KTP A;  1XWT A;  2WY7 A;  3QT3 A;  4ZG8 A;  2GH4 A;  3DPY B;  1UG9 A;  3W5N A;  5GZK A;  3DSS B;  4FUS A;  5KKB A;  2BB6 A;  1O6R A;  2B4F A;  1KRF A;  3RX8 A;  1O6Q A;  3HXD B;  1KKT A;  5DGQ A;  4AYO A;  3GZK A;  3T33 A;  1GLM A;  3RRS A;  1XW2 A;  3CIH A;  3QFZ A;  2QNO A;  3S4B A;  1UT9 A;  3EU8 A;  3DSW B;  3KQ4 A;  3QPF A;  2A8Z A;  1FAE A;  1K72 A;  1JCQ B;  3TF4 A;  3KSL B;  1S64 B;  1D8E B;  1FP3 A;  2JJB A;  1LF9 A;  2H6F B;  1GSZ A;  3M7L A;  4MU9 A;  3M75 A;  1V7X A;  1N94 B;  1TN6 B;  4DOD A;  1WU6 A;  3S9V A;  3S4D A;  3M78 A;  4AYP A;  3D5S A;  2YIK A;  5GW7 A;  1GA2 A;  4EL8 A;  2AHG A;  3WKG A;  4GTM B;  1TNU B;  3SDV A;  1G9J A;  1ULV A;  1SQC A;  1G87 A;  3VXD A;  4CJ1 A;  1V5C A;  3SFX B;  3SDR A;  4D4C A;  3EZ8 A;  4GTQ B;  4CJ0 A;  5E2J A;  5FO8 B;  5GY3 A;  3GT5 A;  4GTT B;  1WU4 A;  3M74 A;  4Z4J A;  2H6I B;  3QRY A;  3QFY A;  3RX7 A;  2IEJ B;  1H3B A;  2B39 A;  1O1T B;  3Q75 B;  2PMV A;  3QG0 A;  1H14 A;  3ACS A;  3ON6 A;  4ZRQ A;  3SDQ A;  4DOE A;  3Q73 B;  4D4D A;  3SDT A;  3SQC A;  1GAH A;  2AHF A;  3P5R A;  2P0V A;  2H6H B;  2PN5 A;  3W7W A;  1W6J A;  3P5P A;  3RSY A;  1DOG A;  4AYR A;  3K11 A;  1TF4 A;  2RI8 A;  4QT9 A;  3DSV B;  2H6G B;  3WKH A;  3PZ1 B;  1H12 A;  2ZZR A;  4LIX A;  2SQC A;  1H3A A;  2RGK A;  4EHM B;  1KRE A;  4KKI A;  4BOJ A;  1GXN A;  1KZO B;  3H3K A;  1LD8 B;  1KZP B;  3Q78 B;  3P2C A;  2DRO A;  3C72 B;  4CE7 A;  4LNG B;  2DRR A;  3X17 A;  1JCR B;  2DRQ A;  2FUZ A;  3HXF B;  1AGM A;  2FBA A;  1KSC A;  3WC3 A;  4ZH1 A;  4C1S A;  1IA7 A;  1NXC A;  3E32 B;  3CU7 A;  3HXE B;  1TNB B;  3M7E A;  1S63 B;  1H36 A;  1JS4 A;  2BBC A;  4LNB B;  2ZIS B;  3OXU A;  1L1Y A;  3Q79 B;  1TNY B;  4L6X A;  3M73 A;  2V8K A;  1GHQ A;  3M72 A;  2NOJ A;  4FXK B;  1LTX B;  1KSD A;  3RJ3 A;  2ZIR B;  4D4B A;  2V8I A;  1NI1 B;  1CLC A;  1G6I A;  2G02 A;  1C3D A;  2CQT A;  3GLY A;  2NVP A;  3DSX B;  3WIR A;  4Q2B A;  1GAI A;  2EAE A;  1FT2 B;  2D8L A;  3OED A;  5DGR A;  1N9A B;  3E34 B;  2AFA A;  3M71 A;  3ANK A;  1FCE A;  4LNV A;  3WIW A;  3SAE A;  4GL3 A;  4JJJ A;  1IS9 A;  5M7Y A;  1HZF A;  3E6U A;  1V7V A;  4Q88 A;  1HCU A;  2EAB A;  4GTS B;  5CZL A;  3DST B;  3AFJ A;  3E33 B;  1H37 A;  2WIN B;  1FT1 B;  2V3P A;  5M7I A;  1N95 B;  3ANJ A;  2R2L B;  4D4A A;  4V1S A;  3RX5 A;  3E73 A;  4MBG B;  4GTV B;  3H7L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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