1NI1B

Imidazole and cyanophenyl farnesyl transferase inhibitors
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
401
structure length
401
Chain Sequence
LYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Protein farnesyltransferase alpha subunit
total genus 137
structure length 401
sequence length 401
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2002-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1ni1B00
1H36A 2WIIB 2XQWA 1TN7B 2V3NA 5FO8B 5JPMB 3C72B 1TNBB 2V3PA 4GTVB 1O6QA 2SQCA 1X81B 2PN5A 3G6JB 4ONTA 1HZFA 4FXGB 1LD7B 4D94A 4MU9A 1DCEB 1JCSB 4GTPB 2I07B 2PMVA 1H3AA 3Q79B 3SQCA 1N9AB 1QBQB 1FPPB 1O79A 3RJ3A 3PZ2B 4ZRQA 4GTMB 1O1RB 2R2LB 1R76A 1TN8B 2IEJB 1N4SB 3D5RA 5AGDA 1SA4B 3PZ3B 3HXBB 1KZOB 1SA5B 4LNVA 4LNGB 1N4RB 1O1SB 5FO9B 3E30B 1H35A 1QSJA 1D8EB 3EUVB 1UMPA 1S64B 1TNZB 1GXMA 2WINB 1KZPB 1LTXB 4GTOB 2BEDB 3DSWB 2WY7A 1GHQA 3KQ4A 3Q78B 1QQFA 2BB5A 1JCRB 1SQCA 1H3CA 1N94B 1MZCB 3DRAB 3KLSA 1JCQB 4D4CA 3DSSB 2WY8A 3K7XA 1N4QB 3SFXB 4ZH1A 3KSLB 1GSZA 2BB6A 2BBCA 3E33B 4V1SA 2XWBB 1W6JA 4GTQB 3SFYB 1GXNA 3DSTB 3E37B 4FXKB 2XWJB 1N4PB 2V8JA 1H3BA 3E32B 3Q73B 5FOBB 4D4AA 3EU5B 1TNYB 2F0YB 4ZRPA 4V1RA 5JPNB 1O6HA 4D4BA 4KKJA 4L9PB 2A73B 4BOJA 3CU7A 2H6GB 1O6RA 3PZ4B 2GOXA 2V8KA 4GTRB 3DSVB 3OEDA 4GTSB 1O1TB 4YDOB 1TN6B 4GTTB 2NOJA 1TNOB 4KKIA 3DSXB 4M76A 3Q7AB 1H39A 5FO7B 1NL4B 3KSQB 4EHMB 1NI1B 1N95B 2ZISB 1FT1B 1D8DB 1GXOA 4BOKA 2H6HB 3DPYB 3HXCB 4D4DA 3Q75B 1LD8B 2ZIRB 1C3DA 3DSUB 4MBGB 3Q7FB 3D5SA 2G02A 1O5MB 1TNUB 2G0DA 3E34B 2B39A 2H6FB 3PZ1B 3HXDB 1S63B 2H6IB 4LNBB 1W6KA 4C1SA 3HXEB 2V8IA 3HXFB 3OXUA 1H37A 4YDEB 1FT2B
chains in the Genus database with same CATH superfamily
5IK9A 5EATA 4AYPA 3AFJA 1KFGA 3SDQA 1H14A 1X9DA 2PN5A 5C05A 2DRQA 4ONTA 4FXGB 2BRPA 1RWGA 1WU6A 1DCEB 4DODA 2PMVA 1FPPB 1V7WA 1FMIA 1N4SB 3HXBB 4LNVA 1AYXA 1L2AA 5FO9B 3QG0A 3S4BA 1H35A 3ANIA 3EQAA 1HN0A 3M7CA 5ILZA 1GXMA 5MEHA 1LTXB 2BEDB 2WY7A 1GHQA 1SQCA 4AYRA 1H3CA 3ACTA 3M01A 3KLSA 5IK0A 1JCQB 3DSSB 1KWFA 3SDRA 5JMDA 3KSLB 2GH4A 2BB6A 3QXFA 3VSMA 2FV0A 2RI8A 4GTQB 3E37B 1N4PB 1RWHA 1TF4A 2RGKA 2AHGA 4RNQA 5FOBB 5M7IA 4OZVA 1TNYB 3VSNA 2OKXA 4L9PB 3RX5A 2YIKA 3W7SA 2EADA 3M71A 3PZ4B 2V8KA 4GTRB 3OEDA 4YDOB 1G9GA 3ON6A 3DSXB 3W5MA 5ILYA 3QFYA 1AGMA 1NL4B 4EHMB 1QAZA 1N95B 1GLMA 3M7BA 3ACSA 1GXOA 2EABA 5IM1A 3DSUB 3Q7FB 1TNUB 3ANKA 1HXAA 2GZ6A 2WCOA 3HXDB 4XUVA 4FUSA 4TF4A 5EAUA 3PMMA 1F9GA 4C1SA 1KREA 1W3YA 4FJQA 1FT2B 2XQWA 2F6DA 1CEMA 2CQTA 3K11A 1XWTA 2FV1A 5CZLA 1N1BA 4L6XA 1N7PA 1X81B 5EASA 3RSYA 4Q2BA 4MU9A 1JCSB 5GW7A 3H2WA 2I07B 2CQSA 3W7WA 3M00A 3QPFA 3E80A 3H3KA 1H3AA 1QBQB 3GT5A 5CD2A 4GTMB 1O1RB 2IEJB 3W7UA 5IK6A 4Z4JA 1LXKA 1FBWA 2A8ZA 3TF4A 2X03A 1FBOA 1D8EB 1F1SA 3QRYA 3P5PA 1UMPA 3M74A 1TNZB 1KZPB 4CJ1A 4YCRA 3X17A 1QQFA 4TXTA 2BB5A 1JCRB 4OZWA 1N94B 3DRAB 3CIHA 4MMHA 1N4QB 4ZH1A 2FUQA 4V1SA 2ONGA 1V7XA 3DSTB 3WKIA 2XWJB 3A0OA 4WU0A 1N22A 5DGRA 1WU5A 3E32B 2AFAA 2Q1FA 2D8LA 4D4AA 1LOHA 5KKBA 5JPNB 1O6HA 4D4BA 1CB8A 4KKJA 3WKHA 4Z4LA 4BOJA 2ZZRA 4AYQA 1ULVA 2ZBLA 3M72A 1O6RA 2GOXA 1OJMA 5JMFA 2BRVX 2NOJA 3SDTA 4KKIA 5DHKA 4CE7A 3Q7AB 4WVBA 2FBAA 1GAIA 3S4AA 5DGQA 2B4FA 1HM3A 2FUTA 1N7NA 3S4DA 5IKHA 1H54A 4WVAA 1GA2A 1NXCA 1X1IA 2G02A 1KS8A 3EU8A 2G0DA 3E34B 3PZ1B 2WYNA 4EL8A 4J5TA 1N24A 4NEIA 3E6UA 5ILHA 3RX7A 4YDEB 3M02A 3QSPA 1H36A 1N20A 1TN7B 5FO8B 3QT9A 4CJ0A 1TNBB 1V5CA 2FUZA 1N7OA 1DL2A 1HZFA 1N21A 4D94A 4GTPB 2E22A 2E24A 1EGUA 3E73A 3PYAA 1O79A 2JJBA 3RJ3A 1HMUA 1FCEA 4F13A 1G9JA 1TN8B 4LIXA 3VXDA 1J0NA 1KRFA 3PZ3B 4GAXA 1IS9A 4JJJA 5DHIA 1RW9A 3GLYA 3M73A 1QSJA 2Z07A 1G6IA 5CA3A 3W5NA 1S64B 4GTOB 2WINB 1HV6A 3M7LA 1XWQA 3Q78B 3GZKA 2VN7A 1HM2A 1H13A 4D4CA 2WY8A 3N0GA 3WKGA 2BBCA 1W6JA 3SFYB 4AYOA 5ILDA 3EZ8A 3M78A 1C82A 5IL8A 3QDEA 2F0YB 1FO2A 3QWTA 4KTPA 3LZ9A 2EACA 3E7JA 4GL3A 1N7RA 3NFVA 4GTTB 1TNOB 2RI9A 4M76A 5FO7B 2AHFA 1RWAA 2XFGA 3H7LA 3N0FA 3QT3A 4L0GA 2J5CA 1D8DB 1UT9A 1UG9A 5ILKA 1HXGA 2H6HB 3DPYB 3HXCB 1X1HA 3RX8A 3SAEA 3WUXA 5GZKA 4MBGB 3M7EA 1O5MB 1FP3A 2DRRA 2B39A 3G4FA 3SDVA 4ZH5A 2H6FB 1HCUA 3T33A 2H6IB 4OK2A 1N1ZA 4QT9A 3ANJA 3OXUA 1DOGA 1H37A 5GY3A 1F9OA 2WIIB 3NNBA 2V3NA 5JPMB 1LF6A 3C72B 3P2CA 1VD5A 2V3PA 1RWFA 1O6QA 3G6JB 2SQCA 4GTVB 1LD7B 2WDAA 4FNVA 1WU4A 3SQCA 3Q79B 2VN4A 1LXMA 1N9AB 1IA6A 1J0MA 3AFLA 3PZ2B 4ZRQA 3M77A 1X1JA 2NVPA 4MMIA 2R2LB 1R76A 1XW2A 3D5RA 3M75A 4OK4A 5AGDA 2BRWA 1SA4B 3VW5A 3QFZA 5ILIA 1F9DA 1KZOB 1SA5B 4LNGB 1N4RB 1O1SB 1G87A 3E30B 1NC5A 1OJPA 2ONHA 1JS4A 3EUVB 4E1YA 4WVCA 3DSWB 3KQ4A 1N7QA 1KKTA 2DRSA 3WIRA 1MZCB 3QXQA 3K7XA 3SFXB 2DROA 1FAEA 4OJZA 1GSZA 5E2JA 3E33B 4ZG8A 2XWBB 1GXNA 3WKFA 4FXKB 2V8JA 3W7XA 5IKAA 1V7VA 1FO3A 3WC3A 1H3BA 3G4DA 1N23A 3Q73B 1OJOA 3EU5B 4ZRPA 3A3VA 4V1RA 2JG0A 1RWCA 3RRSA 1L1YA 2QNOA 2A73B 1CLCA 5M7YA 2D5JA 3CU7A 5IL3A 2H6GB 2JF4A 3WIQA 3RENA 3P5RA 3DSVB 4GTSB 1O1TB 4KTRA 1TN6B 3PYBA 4Q88A 1I8QA 1H39A 1H12A 3KSQB 3WIWA 1NI1B 3SDUA 2ZISB 1HXCA 1FT1B 1OJNA 5ILJA 2EAEA 4DI5A 1IA7A 4BOKA 4DOEA 4D4DA 3Q75B 1LF9A 1LD8B 2ZIRB 1KSCA 3S9VA 1C3DA 2P0VA 1HMWA 1KSDA 1GAHA 3D5SA 3M76A 3W7TA 4F10A 1RQ5A 1K72A 1HX9A 1V5DA 1S63B 3S4CA 4LNBB 1W6KA 1WZZA 3HXEB 3HXFB 2V8IA 3D3IA
chains in the Genus database with same CATH topology
4AYPA 3AFJA 1KFGA 3SDQA 1H14A 1X9DA 2PN5A 2DRQA 4ONTA 4FXGB 1WU6A 1DCEB 4DODA 2PMVA 1FPPB 1V7WA 1FMIA 1N4SB 3HXBB 4LNVA 1AYXA 1L2AA 5FO9B 3QG0A 3S4BA 1H35A 3ANIA 3EQAA 3M7CA 1GXMA 5MEHA 1LTXB 2BEDB 2WY7A 1GHQA 1SQCA 4AYRA 1H3CA 3ACTA 3KLSA 1JCQB 3DSSB 1KWFA 3SDRA 3KSLB 2GH4A 2BB6A 3QXFA 2FV0A 2RI8A 4GTQB 3E37B 1N4PB 1TF4A 2RGKA 2AHGA 5FOBB 5M7IA 1TNYB 2OKXA 4L9PB 3RX5A 2YIKA 3W7SA 2EADA 3M71A 3PZ4B 2V8KA 4GTRB 3OEDA 4YDOB 1G9GA 3ON6A 3DSXB 3W5MA 3QFYA 1AGMA 1NL4B 4EHMB 1N95B 1GLMA 3M7BA 3ACSA 1GXOA 2EABA 3DSUB 3Q7FB 1TNUB 3ANKA 2GZ6A 3HXDB 4XUVA 4FUSA 4TF4A 3PMMA 4C1SA 1KREA 1FT2B 2XQWA 2F6DA 1CEMA 2CQTA 3K11A 1XWTA 2FV1A 5CZLA 4L6XA 1X81B 3RSYA 4Q2BA 4MU9A 1JCSB 5GW7A 3H2WA 2I07B 2CQSA 3W7WA 3QPFA 3H3KA 1H3AA 1QBQB 3GT5A 5CD2A 4GTMB 1O1RB 2IEJB 3W7UA 4Z4JA 1FBWA 2A8ZA 3TF4A 1FBOA 1D8EB 3QRYA 3P5PA 1UMPA 3M74A 1TNZB 1KZPB 4CJ1A 4YCRA 3X17A 1QQFA 4TXTA 2BB5A 1JCRB 1N94B 3DRAB 3CIHA 1N4QB 4ZH1A 4V1SA 1V7XA 3DSTB 3WKIA 2XWJB 4WU0A 5DGRA 1WU5A 3E32B 2AFAA 2D8LA 4D4AA 5KKBA 5JPNB 1O6HA 4D4BA 4KKJA 3WKHA 4Z4LA 4BOJA 2ZZRA 4AYQA 1ULVA 2ZBLA 3M72A 1O6RA 2GOXA 2NOJA 3SDTA 4KKIA 4CE7A 3Q7AB 4WVBA 2FBAA 1GAIA 3S4AA 5DGQA 2B4FA 3S4DA 1H54A 4WVAA 1GA2A 1NXCA 2G02A 1KS8A 3EU8A 2G0DA 3E34B 3PZ1B 2WYNA 4EL8A 4J5TA 3E6UA 3RX7A 4YDEB 3QSPA 1H36A 1TN7B 5FO8B 3QT9A 4CJ0A 1TNBB 1V5CA 2FUZA 1DL2A 1HZFA 4D94A 4GTPB 3E73A 3PYAA 1O79A 2JJBA 3RJ3A 1FCEA 1G9JA 1TN8B 4LIXA 3VXDA 1KRFA 3PZ3B 1IS9A 4JJJA 3GLYA 3M73A 1QSJA 2Z07A 1G6IA 5CA3A 3W5NA 1S64B 4GTOB 2WINB 3M7LA 1XWQA 3Q78B 3GZKA 2VN7A 1H13A 4D4CA 2WY8A 3WKGA 2BBCA 1W6JA 3SFYB 4AYOA 3EZ8A 3M78A 3QDEA 2F0YB 1FO2A 3QWTA 4KTPA 2EACA 4GL3A 4GTTB 1TNOB 2RI9A 4M76A 5FO7B 2AHFA 2XFGA 3H7LA 3QT3A 4L0GA 1D8DB 1UT9A 1UG9A 2H6HB 3DPYB 3HXCB 3RX8A 3SAEA 3WUXA 5GZKA 4MBGB 3M7EA 1O5MB 1FP3A 2DRRA 2B39A 3SDVA 4ZH5A 2H6FB 1HCUA 3T33A 2H6IB 4QT9A 3ANJA 3OXUA 1DOGA 1H37A 5GY3A 1F9OA 2WIIB 2V3NA 5JPMB 1LF6A 3C72B 3P2CA 1VD5A 2V3PA 4GTVB 1O6QA 2SQCA 3G6JB 1LD7B 1WU4A 3SQCA 3Q79B 2VN4A 1N9AB 1IA6A 3PZ2B 4ZRQA 3M77A 2NVPA 2R2LB 1R76A 1XW2A 3D5RA 3M75A 5AGDA 1SA4B 3VW5A 3QFZA 1F9DA 1KZOB 1SA5B 4LNGB 1N4RB 1O1SB 1G87A 3E30B 1NC5A 1JS4A 3EUVB 4WVCA 3DSWB 3KQ4A 1KKTA 2DRSA 3WIRA 1MZCB 3QXQA 3K7XA 3SFXB 2DROA 1FAEA 5E2JA 1GSZA 3E33B 4ZG8A 2XWBB 1GXNA 3WKFA 4FXKB 2V8JA 3W7XA 1V7VA 1FO3A 3WC3A 1H3BA 3Q73B 3EU5B 4ZRPA 3A3VA 4V1RA 2JG0A 3RRSA 1L1YA 2QNOA 2A73B 1CLCA 5M7YA 2D5JA 3CU7A 2H6GB 2JF4A 3WIQA 3RENA 3P5RA 3DSVB 4GTSB 1O1TB 4KTRA 1TN6B 3PYBA 4Q88A 1H39A 1H12A 3KSQB 3WIWA 1NI1B 3SDUA 2ZISB 1FT1B 2EAEA 1IA7A 4BOKA 4DOEA 4D4DA 3Q75B 1LF9A 1LD8B 2ZIRB 1KSCA 3S9VA 1C3DA 2P0VA 1KSDA 3M76A 1GAHA 3D5SA 3W7TA 1RQ5A 1K72A 1V5DA 1S63B 3S4CA 4LNBB 1W6KA 1WZZA 3HXEB 3HXFB 2V8IA 3D3IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1H36 A;  2WII B;  2XQW A;  1TN7 B;  2V3N A;  5FO8 B;  5JPM B;  3C72 B;  1TNB B;  2V3P A;  4GTV B;  1O6Q A;  2SQC A;  1X81 B;  2PN5 A;  3G6J B;  4ONT A;  1HZF A;  4FXG B;  1LD7 B;  4D94 A;  4MU9 A;  1DCE B;  1JCS B;  4GTP B;  2I07 B;  2PMV A;  1H3A A;  3Q79 B;  3SQC A;  1N9A B;  1QBQ B;  1FPP B;  1O79 A;  3RJ3 A;  3PZ2 B;  4ZRQ A;  4GTM B;  1O1R B;  2R2L B;  1R76 A;  1TN8 B;  2IEJ B;  1N4S B;  3D5R A;  5AGD A;  1SA4 B;  3PZ3 B;  3HXB B;  1KZO B;  1SA5 B;  4LNV A;  4LNG B;  1N4R B;  1O1S B;  5FO9 B;  3E30 B;  1H35 A;  1QSJ A;  1D8E B;  3EUV B;  1UMP A;  1S64 B;  1TNZ B;  1GXM A;  2WIN B;  1KZP B;  1LTX B;  4GTO B;  2BED B;  3DSW B;  2WY7 A;  1GHQ A;  3KQ4 A;  3Q78 B;  1QQF A;  2BB5 A;  1JCR B;  1SQC A;  1H3C A;  1N94 B;  1MZC B;  3DRA B;  3KLS A;  1JCQ B;  4D4C A;  3DSS B;  2WY8 A;  3K7X A;  1N4Q B;  3SFX B;  4ZH1 A;  3KSL B;  1GSZ A;  2BB6 A;  2BBC A;  3E33 B;  4V1S A;  2XWB B;  1W6J A;  4GTQ B;  3SFY B;  1GXN A;  3DST B;  3E37 B;  4FXK B;  2XWJ B;  1N4P B;  2V8J A;  1H3B A;  3E32 B;  3Q73 B;  5FOB B;  4D4A A;  3EU5 B;  1TNY B;  2F0Y B;  4ZRP A;  4V1R A;  5JPN B;  1O6H A;  4D4B A;  4KKJ A;  4L9P B;  2A73 B;  4BOJ A;  3CU7 A;  2H6G B;  1O6R A;  3PZ4 B;  2GOX A;  2V8K A;  4GTR B;  3DSV B;  3OED A;  4GTS B;  1O1T B;  4YDO B;  1TN6 B;  4GTT B;  2NOJ A;  1TNO B;  4KKI A;  3DSX B;  4M76 A;  3Q7A B;  1H39 A;  5FO7 B;  1NL4 B;  3KSQ B;  4EHM B;  1NI1 B;  1N95 B;  2ZIS B;  1FT1 B;  1D8D B;  1GXO A;  4BOK A;  2H6H B;  3DPY B;  3HXC B;  4D4D A;  3Q75 B;  1LD8 B;  2ZIR B;  1C3D A;  3DSU B;  4MBG B;  3Q7F B;  3D5S A;  2G02 A;  1O5M B;  1TNU B;  2G0D A;  3E34 B;  2B39 A;  2H6F B;  3PZ1 B;  3HXD B;  1S63 B;  2H6I B;  4LNB B;  1W6K A;  4C1S A;  3HXE B;  2V8I A;  3HXF B;  3OXU A;  1H37 A;  4YDE B;  1FT2 B; 
#chains in the Genus database with same CATH topology
 5IK9 A;  5EAT A;  4AYP A;  3AFJ A;  1KFG A;  3SDQ A;  1H14 A;  1X9D A;  2PN5 A;  5C05 A;  2DRQ A;  4ONT A;  4FXG B;  2BRP A;  1RWG A;  1WU6 A;  1DCE B;  4DOD A;  2PMV A;  1FPP B;  1V7W A;  1FMI A;  1N4S B;  3HXB B;  4LNV A;  1AYX A;  1L2A A;  5FO9 B;  3QG0 A;  3S4B A;  1H35 A;  3ANI A;  3EQA A;  1HN0 A;  3M7C A;  5ILZ A;  1GXM A;  5MEH A;  1LTX B;  2BED B;  2WY7 A;  1GHQ A;  1SQC A;  4AYR A;  1H3C A;  3ACT A;  3M01 A;  3KLS A;  5IK0 A;  1JCQ B;  3DSS B;  1KWF A;  3SDR A;  5JMD A;  3KSL B;  2GH4 A;  2BB6 A;  3QXF A;  3VSM A;  2FV0 A;  2RI8 A;  4GTQ B;  3E37 B;  1N4P B;  1RWH A;  1TF4 A;  2RGK A;  2AHG A;  4RNQ A;  5FOB B;  5M7I A;  4OZV A;  1TNY B;  3VSN A;  2OKX A;  4L9P B;  3RX5 A;  2YIK A;  3W7S A;  2EAD A;  3M71 A;  3PZ4 B;  2V8K A;  4GTR B;  3OED A;  4YDO B;  1G9G A;  3ON6 A;  3DSX B;  3W5M A;  5ILY A;  3QFY A;  1AGM A;  1NL4 B;  4EHM B;  1QAZ A;  1N95 B;  1GLM A;  3M7B A;  3ACS A;  1GXO A;  2EAB A;  5IM1 A;  3DSU B;  3Q7F B;  1TNU B;  3ANK A;  1HXA A;  2GZ6 A;  2WCO A;  3HXD B;  4XUV A;  4FUS A;  4TF4 A;  5EAU A;  3PMM A;  1F9G A;  4C1S A;  1KRE A;  1W3Y A;  4FJQ A;  1FT2 B;  2XQW A;  2F6D A;  1CEM A;  2CQT A;  3K11 A;  1XWT A;  2FV1 A;  5CZL A;  1N1B A;  4L6X A;  1N7P A;  1X81 B;  5EAS A;  3RSY A;  4Q2B A;  4MU9 A;  1JCS B;  5GW7 A;  3H2W A;  2I07 B;  2CQS A;  3W7W A;  3M00 A;  3QPF A;  3E80 A;  3H3K A;  1H3A A;  1QBQ B;  3GT5 A;  5CD2 A;  4GTM B;  1O1R B;  2IEJ B;  3W7U A;  5IK6 A;  4Z4J A;  1LXK A;  1FBW A;  2A8Z A;  3TF4 A;  2X03 A;  1FBO A;  1D8E B;  1F1S A;  3QRY A;  3P5P A;  1UMP A;  3M74 A;  1TNZ B;  1KZP B;  4CJ1 A;  4YCR A;  3X17 A;  1QQF A;  4TXT A;  2BB5 A;  1JCR B;  4OZW A;  1N94 B;  3DRA B;  3CIH A;  4MMH A;  1N4Q B;  4ZH1 A;  2FUQ A;  4V1S A;  2ONG A;  1V7X A;  3DST B;  3WKI A;  2XWJ B;  3A0O A;  4WU0 A;  1N22 A;  5DGR A;  1WU5 A;  3E32 B;  2AFA A;  2Q1F A;  2D8L A;  4D4A A;  1LOH A;  5KKB A;  5JPN B;  1O6H A;  4D4B A;  1CB8 A;  4KKJ A;  3WKH A;  4Z4L A;  4BOJ A;  2ZZR A;  4AYQ A;  1ULV A;  2ZBL A;  3M72 A;  1O6R A;  2GOX A;  1OJM A;  5JMF A;  2BRV X;  2NOJ A;  3SDT A;  4KKI A;  5DHK A;  4CE7 A;  3Q7A B;  4WVB A;  2FBA A;  1GAI A;  3S4A A;  5DGQ A;  2B4F A;  1HM3 A;  2FUT A;  1N7N A;  3S4D A;  5IKH A;  1H54 A;  4WVA A;  1GA2 A;  1NXC A;  1X1I A;  2G02 A;  1KS8 A;  3EU8 A;  2G0D A;  3E34 B;  3PZ1 B;  2WYN A;  4EL8 A;  4J5T A;  1N24 A;  4NEI A;  3E6U A;  5ILH A;  3RX7 A;  4YDE B;  3M02 A;  3QSP A;  1H36 A;  1N20 A;  1TN7 B;  5FO8 B;  3QT9 A;  4CJ0 A;  1TNB B;  1V5C A;  2FUZ A;  1N7O A;  1DL2 A;  1HZF A;  1N21 A;  4D94 A;  4GTP B;  2E22 A;  2E24 A;  1EGU A;  3E73 A;  3PYA A;  1O79 A;  2JJB A;  3RJ3 A;  1HMU A;  1FCE A;  4F13 A;  1G9J A;  1TN8 B;  4LIX A;  3VXD A;  1J0N A;  1KRF A;  3PZ3 B;  4GAX A;  1IS9 A;  4JJJ A;  5DHI A;  1RW9 A;  3GLY A;  3M73 A;  1QSJ A;  2Z07 A;  1G6I A;  5CA3 A;  3W5N A;  1S64 B;  4GTO B;  2WIN B;  1HV6 A;  3M7L A;  1XWQ A;  3Q78 B;  3GZK A;  2VN7 A;  1HM2 A;  1H13 A;  4D4C A;  2WY8 A;  3N0G A;  3WKG A;  2BBC A;  1W6J A;  3SFY B;  4AYO A;  5ILD A;  3EZ8 A;  3M78 A;  1C82 A;  5IL8 A;  3QDE A;  2F0Y B;  1FO2 A;  3QWT A;  4KTP A;  3LZ9 A;  2EAC A;  3E7J A;  4GL3 A;  1N7R A;  3NFV A;  4GTT B;  1TNO B;  2RI9 A;  4M76 A;  5FO7 B;  2AHF A;  1RWA A;  2XFG A;  3H7L A;  3N0F A;  3QT3 A;  4L0G A;  2J5C A;  1D8D B;  1UT9 A;  1UG9 A;  5ILK A;  1HXG A;  2H6H B;  3DPY B;  3HXC B;  1X1H A;  3RX8 A;  3SAE A;  3WUX A;  5GZK A;  4MBG B;  3M7E A;  1O5M B;  1FP3 A;  2DRR A;  2B39 A;  3G4F A;  3SDV A;  4ZH5 A;  2H6F B;  1HCU A;  3T33 A;  2H6I B;  4OK2 A;  1N1Z A;  4QT9 A;  3ANJ A;  3OXU A;  1DOG A;  1H37 A;  5GY3 A;  1F9O A;  2WII B;  3NNB A;  2V3N A;  5JPM B;  1LF6 A;  3C72 B;  3P2C A;  1VD5 A;  2V3P A;  1RWF A;  1O6Q A;  3G6J B;  2SQC A;  4GTV B;  1LD7 B;  2WDA A;  4FNV A;  1WU4 A;  3SQC A;  3Q79 B;  2VN4 A;  1LXM A;  1N9A B;  1IA6 A;  1J0M A;  3AFL A;  3PZ2 B;  4ZRQ A;  3M77 A;  1X1J A;  2NVP A;  4MMI A;  2R2L B;  1R76 A;  1XW2 A;  3D5R A;  3M75 A;  4OK4 A;  5AGD A;  2BRW A;  1SA4 B;  3VW5 A;  3QFZ A;  5ILI A;  1F9D A;  1KZO B;  1SA5 B;  4LNG B;  1N4R B;  1O1S B;  1G87 A;  3E30 B;  1NC5 A;  1OJP A;  2ONH A;  1JS4 A;  3EUV B;  4E1Y A;  4WVC A;  3DSW B;  3KQ4 A;  1N7Q A;  1KKT A;  2DRS A;  3WIR A;  1MZC B;  3QXQ A;  3K7X A;  3SFX B;  2DRO A;  1FAE A;  4OJZ A;  1GSZ A;  5E2J A;  3E33 B;  4ZG8 A;  2XWB B;  1GXN A;  3WKF A;  4FXK B;  2V8J A;  3W7X A;  5IKA A;  1V7V A;  1FO3 A;  3WC3 A;  1H3B A;  3G4D A;  1N23 A;  3Q73 B;  1OJO A;  3EU5 B;  4ZRP A;  3A3V A;  4V1R A;  2JG0 A;  1RWC A;  3RRS A;  1L1Y A;  2QNO A;  2A73 B;  1CLC A;  5M7Y A;  2D5J A;  3CU7 A;  5IL3 A;  2H6G B;  2JF4 A;  3WIQ A;  3REN A;  3P5R A;  3DSV B;  4GTS B;  1O1T B;  4KTR A;  1TN6 B;  3PYB A;  4Q88 A;  1I8Q A;  1H39 A;  1H12 A;  3KSQ B;  3WIW A;  1NI1 B;  3SDU A;  2ZIS B;  1HXC A;  1FT1 B;  1OJN A;  5ILJ A;  2EAE A;  4DI5 A;  1IA7 A;  4BOK A;  4DOE A;  4D4D A;  3Q75 B;  1LF9 A;  1LD8 B;  2ZIR B;  1KSC A;  3S9V A;  1C3D A;  2P0V A;  1HMW A;  1KSD A;  1GAH A;  3D5S A;  3M76 A;  3W7T A;  4F10 A;  1RQ5 A;  1K72 A;  1HX9 A;  1V5D A;  1S63 B;  3S4C A;  4LNB B;  1W6K A;  1WZZ A;  3HXE B;  3HXF B;  2V8I A;  3D3I A; 
#chains in the Genus database with same CATH homology
 4AYP A;  3AFJ A;  1KFG A;  3SDQ A;  1H14 A;  1X9D A;  2PN5 A;  2DRQ A;  4ONT A;  4FXG B;  1WU6 A;  1DCE B;  4DOD A;  2PMV A;  1FPP B;  1V7W A;  1FMI A;  1N4S B;  3HXB B;  4LNV A;  1AYX A;  1L2A A;  5FO9 B;  3QG0 A;  3S4B A;  1H35 A;  3ANI A;  3EQA A;  3M7C A;  1GXM A;  5MEH A;  1LTX B;  2BED B;  2WY7 A;  1GHQ A;  1SQC A;  4AYR A;  1H3C A;  3ACT A;  3KLS A;  1JCQ B;  3DSS B;  1KWF A;  3SDR A;  3KSL B;  2GH4 A;  2BB6 A;  3QXF A;  2FV0 A;  2RI8 A;  4GTQ B;  3E37 B;  1N4P B;  1TF4 A;  2RGK A;  2AHG A;  5FOB B;  5M7I A;  1TNY B;  2OKX A;  4L9P B;  3RX5 A;  2YIK A;  3W7S A;  2EAD A;  3M71 A;  3PZ4 B;  2V8K A;  4GTR B;  3OED A;  4YDO B;  1G9G A;  3ON6 A;  3DSX B;  3W5M A;  3QFY A;  1AGM A;  1NL4 B;  4EHM B;  1N95 B;  1GLM A;  3M7B A;  3ACS A;  1GXO A;  2EAB A;  3DSU B;  3Q7F B;  1TNU B;  3ANK A;  2GZ6 A;  3HXD B;  4XUV A;  4FUS A;  4TF4 A;  3PMM A;  4C1S A;  1KRE A;  1FT2 B;  2XQW A;  2F6D A;  1CEM A;  2CQT A;  3K11 A;  1XWT A;  2FV1 A;  5CZL A;  4L6X A;  1X81 B;  3RSY A;  4Q2B A;  4MU9 A;  1JCS B;  5GW7 A;  3H2W A;  2I07 B;  2CQS A;  3W7W A;  3QPF A;  3H3K A;  1H3A A;  1QBQ B;  3GT5 A;  5CD2 A;  4GTM B;  1O1R B;  2IEJ B;  3W7U A;  4Z4J A;  1FBW A;  2A8Z A;  3TF4 A;  1FBO A;  1D8E B;  3QRY A;  3P5P A;  1UMP A;  3M74 A;  1TNZ B;  1KZP B;  4CJ1 A;  4YCR A;  3X17 A;  1QQF A;  4TXT A;  2BB5 A;  1JCR B;  1N94 B;  3DRA B;  3CIH A;  1N4Q B;  4ZH1 A;  4V1S A;  1V7X A;  3DST B;  3WKI A;  2XWJ B;  4WU0 A;  5DGR A;  1WU5 A;  3E32 B;  2AFA A;  2D8L A;  4D4A A;  5KKB A;  5JPN B;  1O6H A;  4D4B A;  4KKJ A;  3WKH A;  4Z4L A;  4BOJ A;  2ZZR A;  4AYQ A;  1ULV A;  2ZBL A;  3M72 A;  1O6R A;  2GOX A;  2NOJ A;  3SDT A;  4KKI A;  4CE7 A;  3Q7A B;  4WVB A;  2FBA A;  1GAI A;  3S4A A;  5DGQ A;  2B4F A;  3S4D A;  1H54 A;  4WVA A;  1GA2 A;  1NXC A;  2G02 A;  1KS8 A;  3EU8 A;  2G0D A;  3E34 B;  3PZ1 B;  2WYN A;  4EL8 A;  4J5T A;  3E6U A;  3RX7 A;  4YDE B;  3QSP A;  1H36 A;  1TN7 B;  5FO8 B;  3QT9 A;  4CJ0 A;  1TNB B;  1V5C A;  2FUZ A;  1DL2 A;  1HZF A;  4D94 A;  4GTP B;  3E73 A;  3PYA A;  1O79 A;  2JJB A;  3RJ3 A;  1FCE A;  1G9J A;  1TN8 B;  4LIX A;  3VXD A;  1KRF A;  3PZ3 B;  1IS9 A;  4JJJ A;  3GLY A;  3M73 A;  1QSJ A;  2Z07 A;  1G6I A;  5CA3 A;  3W5N A;  1S64 B;  4GTO B;  2WIN B;  3M7L A;  1XWQ A;  3Q78 B;  3GZK A;  2VN7 A;  1H13 A;  4D4C A;  2WY8 A;  3WKG A;  2BBC A;  1W6J A;  3SFY B;  4AYO A;  3EZ8 A;  3M78 A;  3QDE A;  2F0Y B;  1FO2 A;  3QWT A;  4KTP A;  2EAC A;  4GL3 A;  4GTT B;  1TNO B;  2RI9 A;  4M76 A;  5FO7 B;  2AHF A;  2XFG A;  3H7L A;  3QT3 A;  4L0G A;  1D8D B;  1UT9 A;  1UG9 A;  2H6H B;  3DPY B;  3HXC B;  3RX8 A;  3SAE A;  3WUX A;  5GZK A;  4MBG B;  3M7E A;  1O5M B;  1FP3 A;  2DRR A;  2B39 A;  3SDV A;  4ZH5 A;  2H6F B;  1HCU A;  3T33 A;  2H6I B;  4QT9 A;  3ANJ A;  3OXU A;  1DOG A;  1H37 A;  5GY3 A;  1F9O A;  2WII B;  2V3N A;  5JPM B;  1LF6 A;  3C72 B;  3P2C A;  1VD5 A;  2V3P A;  4GTV B;  1O6Q A;  2SQC A;  3G6J B;  1LD7 B;  1WU4 A;  3SQC A;  3Q79 B;  2VN4 A;  1N9A B;  1IA6 A;  3PZ2 B;  4ZRQ A;  3M77 A;  2NVP A;  2R2L B;  1R76 A;  1XW2 A;  3D5R A;  3M75 A;  5AGD A;  1SA4 B;  3VW5 A;  3QFZ A;  1F9D A;  1KZO B;  1SA5 B;  4LNG B;  1N4R B;  1O1S B;  1G87 A;  3E30 B;  1NC5 A;  1JS4 A;  3EUV B;  4WVC A;  3DSW B;  3KQ4 A;  1KKT A;  2DRS A;  3WIR A;  1MZC B;  3QXQ A;  3K7X A;  3SFX B;  2DRO A;  1FAE A;  5E2J A;  1GSZ A;  3E33 B;  4ZG8 A;  2XWB B;  1GXN A;  3WKF A;  4FXK B;  2V8J A;  3W7X A;  1V7V A;  1FO3 A;  3WC3 A;  1H3B A;  3Q73 B;  3EU5 B;  4ZRP A;  3A3V A;  4V1R A;  2JG0 A;  3RRS A;  1L1Y A;  2QNO A;  2A73 B;  1CLC A;  5M7Y A;  2D5J A;  3CU7 A;  2H6G B;  2JF4 A;  3WIQ A;  3REN A;  3P5R A;  3DSV B;  4GTS B;  1O1T B;  4KTR A;  1TN6 B;  3PYB A;  4Q88 A;  1H39 A;  1H12 A;  3KSQ B;  3WIW A;  1NI1 B;  3SDU A;  2ZIS B;  1FT1 B;  2EAE A;  1IA7 A;  4BOK A;  4DOE A;  4D4D A;  3Q75 B;  1LF9 A;  1LD8 B;  2ZIR B;  1KSC A;  3S9V A;  1C3D A;  2P0V A;  1KSD A;  3M76 A;  1GAH A;  3D5S A;  3W7T A;  1RQ5 A;  1K72 A;  1V5D A;  1S63 B;  3S4C A;  4LNB B;  1W6K A;  1WZZ A;  3HXE B;  3HXF B;  2V8I A;  3D3I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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