1NI1B

Imidazole and cyanophenyl farnesyl transferase inhibitors
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
401
structure length
401
Chain Sequence
LYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Protein farnesyltransferase alpha subunit
total genus 137
structure length 401
sequence length 401
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2002-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 1ni1B00
1O1RB 4L9PB 1H36A 1W6KA 1LTXB 2NOJA 3K7XA 1H3BA 4ZH1A 3E32B 1LD7B 1O1SB 1TNUB 3HXFB 3Q78B 4D4BA 2WINB 1D8EB 1O1TB 4YDEB 3HXBB 4D4AA 3OEDA 3DRAB 1GXOA 5FOBB 4M76A 3HXEB 4LNGB 2BB5A 1SA5B 4ZRPA 3Q7FB 1KZOB 1N4QB 3SFXB 4FXGB 2PMVA 3C72B 3KSLB 3D5RA 1SA4B 1MZCB 2A73B 4LNBB 1JCQB 1TN7B 3DSXB 2H6IB 1FPPB 2H6HB 2V3PA 2ZISB 3DSVB 2ZIRB 3DPYB 4MBGB 5FO9B 2WY8A 2G0DA 3KLSA 2XWJB 1S64B 3PZ4B 3E33B 4GTRB 4D94A 3RJ3A 1TN8B 3DSSB 2GOXA 1C3DA 1O6QA 2V3NA 1H3CA 1D8DB 4GTPB 4GTSB 3OXUA 4V1RA 1O6RA 3PZ3B 3G6JB 4EHMB 5FO8B 1N4RB 1H39A 2V8IA 1GXMA 3Q79B 2V8KA 1QQFA 3KSQB 4LNVA 3HXDB 2R2LB 4GTTB 4BOJA 3E30B 3SQCA 1LD8B 1O5MB 1TNOB 3KQ4A 4D4DA 1N95B 1HZFA 3Q73B 1X81B 2I07B 5JPNB 2BEDB 4ONTA 1QSJA 2G02A 3SFYB 1TNYB 3D5SA 1W6JA 2F0YB 4KKIA 2BB6A 4V1SA 3E37B 3HXCB 1UMPA 1S63B 2V8JA 4BOKA 4C1SA 2XWBB 3EU5B 1FT2B 1JCRB 1FT1B 2H6FB 3DSTB 1GHQA 4GTOB 1QBQB 4GTQB 3Q75B 1O6HA 4GTMB 1H37A 4FXKB 4MU9A 1N4PB 1KZPB 1TNBB 1GXNA 3Q7AB 1TN6B 5FO7B 4YDOB 1O79A 5JPMB 2B39A 2H6GB 1N94B 4D4CA 2SQCA 3PZ2B 2PN5A 1N9AB 4GTVB 2WY7A 3CU7A 2IEJB 2WIIB 1SQCA 3DSUB 3PZ1B 1DCEB 1NI1B 3E34B 5AGDA 1R76A 1H3AA 1N4SB 2XQWA 1NL4B 1H35A 3DSWB 1TNZB 4KKJA 4ZRQA 3EUVB 1GSZA 1JCSB 2BBCA
chains in the Genus database with same CATH superfamily
1LTXB 1N23A 1H3BA 3G4DA 4ZH1A 1DOGA 5ILHA 1FP3A 1TNUB 5C05A 2A8ZA 3SDUA 1D8EB 3ANJA 3M7EA 1GXOA 2WCOA 3E6UA 2BB5A 1KZOB 3SFXB 3KSLB 3WKGA 5IL8A 1FPPB 2H6HB 1LF9A 2ZISB 3VXDA 2ZIRB 5CA3A 4CJ0A 4E1YA 3SDQA 5MEHA 3KLSA 2D8LA 2XWJB 3M7BA 3X17A 1H12A 1S64B 1F9GA 3N0GA 1HV6A 1O6QA 2J5CA 1RWGA 2VN4A 2RI9A 1O6RA 2CQTA 1W3YA 1H39A 2V8IA 3LZ9A 4Q2BA 1N7QA 1QQFA 3E73A 3KSQB 4LNVA 2R2LB 1GLMA 3SDTA 3AFLA 3SQCA 4BOJA 1LD8B 3KQ4A 3M71A 3Q73B 1OJNA 1IA6A 2I07B 5JPNB 1CB8A 3W7TA 2G02A 4MMIA 3QPFA 3H7LA 4ZH5A 1VD5A 5DHIA 3HXCB 4C1SA 3S4AA 3RX7A 1KFGA 2QNOA 2FV1A 4GTOB 4GTQB 5IK0A 3PYAA 4FXKB 1N20A 3QDEA 1J0NA 1TNBB 5IM1A 1TN6B 3WIWA 1HMWA 4JJJA 2EABA 2GH4A 1V7VA 3QG0A 1G6IA 5JPMB 4OK2A 3W7SA 4D4CA 2SQCA 3NNBA 5ILZA 1L1YA 3PZ2B 2PN5A 3P5RA 1KSDA 1KS8A 4F10A 5GW7A 1R76A 2GZ6A 5IKHA 3DSWB 3CIHA 1V5CA 4L0GA 1GSZA 1H36A 3K7XA 1KSCA 3E32B 3WUXA 1J0MA 3G4FA 3HXFB 3EZ8A 1X9DA 4D4BA 1N7RA 2WINB 3AFJA 1O1TB 1OJPA 3M73A 3A0OA 5E2JA 3DRAB 3NFVA 3W7XA 1V5DA 4M76A 4LNGB 1LF6A 4GL3A 1SA5B 4ZRPA 1UT9A 2AHGA 2D5JA 4AYOA 4FJQA 1GAIA 4LNBB 3PMMA 2H6IB 1CEMA 1KKTA 3DSVB 4GAXA 3DPYB 4MBGB 3P2CA 1G9GA 2WY8A 2FBAA 5EASA 4FNVA 4TF4A 3VSNA 1RW9A 2JF4A 3PZ4B 3E33B 3TF4A 3RJ3A 1TN8B 1FBWA 3DSSB 2WDAA 3QFYA 2V3NA 1H3CA 1D8DB 1N7OA 3N0FA 1H54A 3G6JB 5IL3A 1NC5A 3WKHA 5ILYA 3H2WA 3QT3A 5IK9A 2FUZA 1N1ZA 2DRRA 1G9JA 2DRSA 4LIXA 1LXMA 5JMFA 2BEDB 4ONTA 5M7IA 1KRFA 1QSJA 1TNYB 1V7XA 3GZKA 2AFAA 2F0YB 4Q88A 2CQSA 1N7PA 1AYXA 3P5PA 4OZWA 3EU5B 1WU6A 1FT2B 4QT9A 1H14A 2H6FB 4ZG8A 1QBQB 4GTMB 2NVPA 1IS9A 1F1SA 1N4PB 1KZPB 1HN0A 4CJ1A 1N7NA 5FO7B 4YDOB 3EQAA 3QFZA 1O79A 2WYNA 4RNQA 1GA2A 2AHFA 3SAEA 1JS4A 1N9AB 5CZLA 2WY7A 1N24A 3CU7A 2IEJB 1N1BA 3M7CA 1NI1B 3QSPA 3QRYA 3SDVA 1H3AA 1NXCA 1H35A 2E22A 1CLCA 4KTPA 3M75A 2X03A 2E24A 2EADA 1FAEA 3EUVB 1O1RB 2VN7A 4OK4A 1RQ5A 1LD7B 3E7JA 3ON6A 1IA7A 3Q78B 2EACA 3RENA 4WVBA 3WKIA 4YDEB 3HXBB 5EAUA 3OEDA 4D4AA 4Z4LA 1EGUA 3HXEB 1RWCA 5ILKA 2Q1FA 3VW5A 4FXGB 3C72B 2DROA 1OJMA 3D5RA 1SA4B 2A73B 1TN7B 1N22A 3DSXB 2BRPA 1X1JA 2V3PA 4F13A 3M74A 5FO9B 3QXQA 2G0DA 4OZVA 4OJZA 3WKFA 4TXTA 3ACSA 4CE7A 1H13A 4D94A 1X1IA 1V7WA 2GOXA 3D3IA 4GTPB 4NEIA 4V1RA 4GTSB 1N21A 3OXUA 2P0VA 1C82A 3RSYA 3M00A 1FBOA 4XUVA 5GY3A 3PZ3B 2F6DA 4EHMB 1HXAA 2V8KA 1F9OA 3HXDB 4GTTB 3E30B 1FO2A 3SDRA 2BRWA 3S4DA 1N95B 4L6XA 1WU5A 1ULVA 3D5SA 1KREA 3E37B 1UMPA 1S63B 2V8JA 5GZKA 3QT9A 3GT5A 3K11A 1XWQA 1GHQA 4WU0A 3Q75B 1O6HA 4MU9A 4DI5A 1RWFA 1GXNA 3Q7AB 3RX5A 5JMDA 5KKBA 3W5MA 4AYRA 2BRVX 2H6GB 2FUTA 1N94B 1LXKA 3ANKA 3M7LA 1UG9A 2RGKA 4KTRA 2WIIB 1SQCA 3PZ1B 1DCEB 5AGDA 3RRSA 1N4SB 2XQWA 1RWAA 1NL4B 3M76A 1TNZB 3PYBA 3QXFA 4Z4JA 4KKJA 4ZRQA 1RWHA 3VSMA 1GAHA 4FUSA 1JCSB 2BBCA 3A3VA 1I8QA 4L9PB 3S4BA 3S4CA 2NOJA 1W6KA 4YCRA 1O1SB 3S9VA 1L2AA 1FO3A 4DOEA 1HMUA 1WZZA 2Z07A 5FOBB 2FUQA 2ZZRA 5DHKA 4DODA 5EATA 5ILDA 4AYQA 3Q7FB 1HM3A 1N4QB 2JG0A 2ZBLA 2PMVA 4WVAA 1XW2A 1MZCB 3H3KA 3EU8A 1FMIA 1JCQB 3M01A 1XWTA 1LOHA 4J5TA 1TF4A 3ANIA 2ONHA 2FV0A 3WC3A 1HM2A 1HXGA 2YIKA 5CD2A 1WU4A 2OKXA 5ILIA 4GTRB 1C3DA 4D4DA 3QWTA 5ILJA 2ONGA 5FO8B 1N4RB 1GXMA 1HX9A 3Q79B 1HCUA 1F9DA 1HXCA 4EL8A 3M02A 2EAEA 1O5MB 1TNOB 1G87A 1HZFA 1OJOA 1X81B 3SFYB 1W6JA 4KKIA 2BB6A 4V1SA 1DL2A 2JJBA 3M72A 4BOKA 3M78A 2XWBB 3ACTA 3W7WA 1JCRB 1FT1B 1KWFA 3DSTB 3E80A 4WVCA 1H37A 4AYPA 5IK6A 5IKAA 1QAZA 4MMHA 3T33A 2B39A 2B4FA 1K72A 1FCEA 2RI8A 3WIQA 4GTVB 5DGQA 3DSUB 5DGRA 3W7UA 3E34B 3GLYA 2XFGA 1AGMA 2DRQA 1X1HA 5M7YA 3WIRA 3RX8A 3W5NA 3M77A
chains in the Genus database with same CATH topology
1LTXB 1H3BA 4ZH1A 1DOGA 1FP3A 1TNUB 2A8ZA 3SDUA 1D8EB 3ANJA 3M7EA 1GXOA 3E6UA 2BB5A 1KZOB 3SFXB 3KSLB 3WKGA 1FPPB 2H6HB 1LF9A 2ZISB 3VXDA 2ZIRB 5CA3A 4CJ0A 3SDQA 5MEHA 3KLSA 2D8LA 2XWJB 3M7BA 3X17A 1H12A 1S64B 1O6QA 2VN4A 2RI9A 1O6RA 2CQTA 1H39A 2V8IA 4Q2BA 1QQFA 3E73A 3KSQB 4LNVA 2R2LB 1GLMA 3SDTA 3SQCA 4BOJA 1LD8B 3KQ4A 3M71A 3Q73B 1IA6A 2I07B 5JPNB 3W7TA 2G02A 3QPFA 3H7LA 4ZH5A 1VD5A 3HXCB 4C1SA 3S4AA 3RX7A 1KFGA 2QNOA 2FV1A 4GTOB 4GTQB 3PYAA 4FXKB 3QDEA 1TNBB 1TN6B 3WIWA 4JJJA 2EABA 2GH4A 1V7VA 3QG0A 1G6IA 5JPMB 3W7SA 4D4CA 2SQCA 1L1YA 3PZ2B 2PN5A 3P5RA 1KSDA 1KS8A 5GW7A 1R76A 2GZ6A 3DSWB 3CIHA 1V5CA 4L0GA 1GSZA 1H36A 3K7XA 1KSCA 3E32B 3WUXA 3HXFB 3EZ8A 1X9DA 4D4BA 2WINB 3AFJA 1O1TB 3M73A 5E2JA 3DRAB 3W7XA 1V5DA 4M76A 4LNGB 1LF6A 4GL3A 1SA5B 4ZRPA 1UT9A 2AHGA 2D5JA 4AYOA 1GAIA 4LNBB 3PMMA 2H6IB 1CEMA 1KKTA 3DSVB 3DPYB 4MBGB 3P2CA 1G9GA 2WY8A 2FBAA 4TF4A 2JF4A 3PZ4B 3E33B 3TF4A 3RJ3A 1TN8B 1FBWA 3DSSB 3QFYA 2V3NA 1H3CA 1D8DB 1H54A 3G6JB 1NC5A 3WKHA 3H2WA 3QT3A 2FUZA 2DRRA 1G9JA 2DRSA 4LIXA 2BEDB 4ONTA 5M7IA 1KRFA 1QSJA 1TNYB 1V7XA 3GZKA 2AFAA 2F0YB 4Q88A 2CQSA 1AYXA 3P5PA 3EU5B 1WU6A 1FT2B 4QT9A 1H14A 2H6FB 4ZG8A 1QBQB 4GTMB 2NVPA 1IS9A 1N4PB 1KZPB 4CJ1A 5FO7B 4YDOB 3EQAA 3QFZA 1O79A 2WYNA 1GA2A 2AHFA 3SAEA 1JS4A 1N9AB 5CZLA 2WY7A 3CU7A 2IEJB 3M7CA 1NI1B 3QSPA 3QRYA 3SDVA 1H3AA 1NXCA 1H35A 4KTPA 1CLCA 3M75A 2EADA 1FAEA 3EUVB 1O1RB 2VN7A 1RQ5A 1LD7B 3ON6A 1IA7A 3Q78B 2EACA 3RENA 4WVBA 3WKIA 4YDEB 3HXBB 4D4AA 3OEDA 4Z4LA 3HXEB 3VW5A 4FXGB 3C72B 2DROA 3D5RA 1SA4B 2A73B 1TN7B 3DSXB 2V3PA 3M74A 5FO9B 3QXQA 2G0DA 3WKFA 4TXTA 3ACSA 4CE7A 1H13A 4D94A 1V7WA 2GOXA 3D3IA 4GTPB 4V1RA 4GTSB 3OXUA 2P0VA 3RSYA 1FBOA 4XUVA 5GY3A 3PZ3B 2F6DA 4EHMB 2V8KA 1F9OA 3HXDB 4GTTB 3E30B 1FO2A 3SDRA 3S4DA 1N95B 4L6XA 1WU5A 1ULVA 3D5SA 1KREA 3E37B 1UMPA 1S63B 2V8JA 5GZKA 3QT9A 3GT5A 3K11A 1XWQA 1GHQA 4WU0A 3Q75B 1O6HA 4MU9A 1GXNA 3Q7AB 3RX5A 5KKBA 3W5MA 4AYRA 2H6GB 1N94B 3ANKA 3M7LA 1UG9A 2RGKA 4KTRA 2WIIB 1SQCA 3PZ1B 1DCEB 5AGDA 3RRSA 1N4SB 2XQWA 1NL4B 3M76A 1TNZB 3PYBA 3QXFA 4Z4JA 4KKJA 4ZRQA 4FUSA 1GAHA 1JCSB 3A3VA 2BBCA 4L9PB 3S4BA 3S4CA 2NOJA 1W6KA 4YCRA 1O1SB 3S9VA 1L2AA 1FO3A 4DOEA 1WZZA 2Z07A 5FOBB 2ZZRA 4DODA 4AYQA 3Q7FB 4WVAA 1N4QB 2JG0A 2ZBLA 2PMVA 1XW2A 1MZCB 3H3KA 3EU8A 1FMIA 1JCQB 1XWTA 4J5TA 1TF4A 3ANIA 2FV0A 3WC3A 2YIKA 5CD2A 1WU4A 2OKXA 4GTRB 1C3DA 4D4DA 3QWTA 5FO8B 1N4RB 1GXMA 3Q79B 1HCUA 1F9DA 4EL8A 2EAEA 1O5MB 1TNOB 1G87A 1HZFA 1X81B 3SFYB 1W6JA 4KKIA 2BB6A 4V1SA 1DL2A 2JJBA 3M72A 4BOKA 3M78A 2XWBB 3ACTA 3W7WA 1JCRB 1FT1B 1KWFA 3DSTB 4WVCA 1H37A 4AYPA 3T33A 2B39A 2B4FA 1K72A 1FCEA 2RI8A 3WIQA 4GTVB 5DGQA 3DSUB 5DGRA 3W7UA 3E34B 3GLYA 2XFGA 1AGMA 2DRQA 3WIRA 5M7YA 3RX8A 3W5NA 3M77A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O1R B;  4L9P B;  1H36 A;  1W6K A;  1LTX B;  2NOJ A;  3K7X A;  1H3B A;  4ZH1 A;  3E32 B;  1LD7 B;  1O1S B;  1TNU B;  3HXF B;  3Q78 B;  4D4B A;  2WIN B;  1D8E B;  1O1T B;  4YDE B;  3HXB B;  4D4A A;  3OED A;  3DRA B;  1GXO A;  5FOB B;  4M76 A;  3HXE B;  4LNG B;  2BB5 A;  1SA5 B;  4ZRP A;  3Q7F B;  1KZO B;  1N4Q B;  3SFX B;  4FXG B;  2PMV A;  3C72 B;  3KSL B;  3D5R A;  1SA4 B;  1MZC B;  2A73 B;  4LNB B;  1JCQ B;  1TN7 B;  3DSX B;  2H6I B;  1FPP B;  2H6H B;  2V3P A;  2ZIS B;  3DSV B;  2ZIR B;  3DPY B;  4MBG B;  5FO9 B;  2WY8 A;  2G0D A;  3KLS A;  2XWJ B;  1S64 B;  3PZ4 B;  3E33 B;  4GTR B;  4D94 A;  3RJ3 A;  1TN8 B;  3DSS B;  2GOX A;  1C3D A;  1O6Q A;  2V3N A;  1H3C A;  1D8D B;  4GTP B;  4GTS B;  3OXU A;  4V1R A;  1O6R A;  3PZ3 B;  3G6J B;  4EHM B;  5FO8 B;  1N4R B;  1H39 A;  2V8I A;  1GXM A;  3Q79 B;  2V8K A;  1QQF A;  3KSQ B;  4LNV A;  3HXD B;  2R2L B;  4GTT B;  4BOJ A;  3E30 B;  3SQC A;  1LD8 B;  1O5M B;  1TNO B;  3KQ4 A;  4D4D A;  1N95 B;  1HZF A;  3Q73 B;  1X81 B;  2I07 B;  5JPN B;  2BED B;  4ONT A;  1QSJ A;  2G02 A;  3SFY B;  1TNY B;  3D5S A;  1W6J A;  2F0Y B;  4KKI A;  2BB6 A;  4V1S A;  3E37 B;  3HXC B;  1UMP A;  1S63 B;  2V8J A;  4BOK A;  4C1S A;  2XWB B;  3EU5 B;  1FT2 B;  1JCR B;  1FT1 B;  2H6F B;  3DST B;  1GHQ A;  4GTO B;  1QBQ B;  4GTQ B;  3Q75 B;  1O6H A;  4GTM B;  1H37 A;  4FXK B;  4MU9 A;  1N4P B;  1KZP B;  1TNB B;  1GXN A;  3Q7A B;  1TN6 B;  5FO7 B;  4YDO B;  1O79 A;  5JPM B;  2B39 A;  2H6G B;  1N94 B;  4D4C A;  2SQC A;  3PZ2 B;  2PN5 A;  1N9A B;  4GTV B;  2WY7 A;  3CU7 A;  2IEJ B;  2WII B;  1SQC A;  3DSU B;  3PZ1 B;  1DCE B;  1NI1 B;  3E34 B;  5AGD A;  1R76 A;  1H3A A;  1N4S B;  2XQW A;  1NL4 B;  1H35 A;  3DSW B;  1TNZ B;  4KKJ A;  4ZRQ A;  3EUV B;  1GSZ A;  1JCS B;  2BBC A; 
#chains in the Genus database with same CATH topology
 1LTX B;  1N23 A;  1H3B A;  3G4D A;  4ZH1 A;  1DOG A;  5ILH A;  1FP3 A;  1TNU B;  5C05 A;  2A8Z A;  3SDU A;  1D8E B;  3ANJ A;  3M7E A;  1GXO A;  2WCO A;  3E6U A;  2BB5 A;  1KZO B;  3SFX B;  3KSL B;  3WKG A;  5IL8 A;  1FPP B;  2H6H B;  1LF9 A;  2ZIS B;  3VXD A;  2ZIR B;  5CA3 A;  4CJ0 A;  4E1Y A;  3SDQ A;  5MEH A;  3KLS A;  2D8L A;  2XWJ B;  3M7B A;  3X17 A;  1H12 A;  1S64 B;  1F9G A;  3N0G A;  1HV6 A;  1O6Q A;  2J5C A;  1RWG A;  2VN4 A;  2RI9 A;  1O6R A;  2CQT A;  1W3Y A;  1H39 A;  2V8I A;  3LZ9 A;  4Q2B A;  1N7Q A;  1QQF A;  3E73 A;  3KSQ B;  4LNV A;  2R2L B;  1GLM A;  3SDT A;  3AFL A;  3SQC A;  4BOJ A;  1LD8 B;  3KQ4 A;  3M71 A;  3Q73 B;  1OJN A;  1IA6 A;  2I07 B;  5JPN B;  1CB8 A;  3W7T A;  2G02 A;  4MMI A;  3QPF A;  3H7L A;  4ZH5 A;  1VD5 A;  5DHI A;  3HXC B;  4C1S A;  3S4A A;  3RX7 A;  1KFG A;  2QNO A;  2FV1 A;  4GTO B;  4GTQ B;  5IK0 A;  3PYA A;  4FXK B;  1N20 A;  3QDE A;  1J0N A;  1TNB B;  5IM1 A;  1TN6 B;  3WIW A;  1HMW A;  4JJJ A;  2EAB A;  2GH4 A;  1V7V A;  3QG0 A;  1G6I A;  5JPM B;  4OK2 A;  3W7S A;  4D4C A;  2SQC A;  3NNB A;  5ILZ A;  1L1Y A;  3PZ2 B;  2PN5 A;  3P5R A;  1KSD A;  1KS8 A;  4F10 A;  5GW7 A;  1R76 A;  2GZ6 A;  5IKH A;  3DSW B;  3CIH A;  1V5C A;  4L0G A;  1GSZ A;  1H36 A;  3K7X A;  1KSC A;  3E32 B;  3WUX A;  1J0M A;  3G4F A;  3HXF B;  3EZ8 A;  1X9D A;  4D4B A;  1N7R A;  2WIN B;  3AFJ A;  1O1T B;  1OJP A;  3M73 A;  3A0O A;  5E2J A;  3DRA B;  3NFV A;  3W7X A;  1V5D A;  4M76 A;  4LNG B;  1LF6 A;  4GL3 A;  1SA5 B;  4ZRP A;  1UT9 A;  2AHG A;  2D5J A;  4AYO A;  4FJQ A;  1GAI A;  4LNB B;  3PMM A;  2H6I B;  1CEM A;  1KKT A;  3DSV B;  4GAX A;  3DPY B;  4MBG B;  3P2C A;  1G9G A;  2WY8 A;  2FBA A;  5EAS A;  4FNV A;  4TF4 A;  3VSN A;  1RW9 A;  2JF4 A;  3PZ4 B;  3E33 B;  3TF4 A;  3RJ3 A;  1TN8 B;  1FBW A;  3DSS B;  2WDA A;  3QFY A;  2V3N A;  1H3C A;  1D8D B;  1N7O A;  3N0F A;  1H54 A;  3G6J B;  5IL3 A;  1NC5 A;  3WKH A;  5ILY A;  3H2W A;  3QT3 A;  5IK9 A;  2FUZ A;  1N1Z A;  2DRR A;  1G9J A;  2DRS A;  4LIX A;  1LXM A;  5JMF A;  2BED B;  4ONT A;  5M7I A;  1KRF A;  1QSJ A;  1TNY B;  1V7X A;  3GZK A;  2AFA A;  2F0Y B;  4Q88 A;  2CQS A;  1N7P A;  1AYX A;  3P5P A;  4OZW A;  3EU5 B;  1WU6 A;  1FT2 B;  4QT9 A;  1H14 A;  2H6F B;  4ZG8 A;  1QBQ B;  4GTM B;  2NVP A;  1IS9 A;  1F1S A;  1N4P B;  1KZP B;  1HN0 A;  4CJ1 A;  1N7N A;  5FO7 B;  4YDO B;  3EQA A;  3QFZ A;  1O79 A;  2WYN A;  4RNQ A;  1GA2 A;  2AHF A;  3SAE A;  1JS4 A;  1N9A B;  5CZL A;  2WY7 A;  1N24 A;  3CU7 A;  2IEJ B;  1N1B A;  3M7C A;  1NI1 B;  3QSP A;  3QRY A;  3SDV A;  1H3A A;  1NXC A;  1H35 A;  2E22 A;  1CLC A;  4KTP A;  3M75 A;  2X03 A;  2E24 A;  2EAD A;  1FAE A;  3EUV B;  1O1R B;  2VN7 A;  4OK4 A;  1RQ5 A;  1LD7 B;  3E7J A;  3ON6 A;  1IA7 A;  3Q78 B;  2EAC A;  3REN A;  4WVB A;  3WKI A;  4YDE B;  3HXB B;  5EAU A;  3OED A;  4D4A A;  4Z4L A;  1EGU A;  3HXE B;  1RWC A;  5ILK A;  2Q1F A;  3VW5 A;  4FXG B;  3C72 B;  2DRO A;  1OJM A;  3D5R A;  1SA4 B;  2A73 B;  1TN7 B;  1N22 A;  3DSX B;  2BRP A;  1X1J A;  2V3P A;  4F13 A;  3M74 A;  5FO9 B;  3QXQ A;  2G0D A;  4OZV A;  4OJZ A;  3WKF A;  4TXT A;  3ACS A;  4CE7 A;  1H13 A;  4D94 A;  1X1I A;  1V7W A;  2GOX A;  3D3I A;  4GTP B;  4NEI A;  4V1R A;  4GTS B;  1N21 A;  3OXU A;  2P0V A;  1C82 A;  3RSY A;  3M00 A;  1FBO A;  4XUV A;  5GY3 A;  3PZ3 B;  2F6D A;  4EHM B;  1HXA A;  2V8K A;  1F9O A;  3HXD B;  4GTT B;  3E30 B;  1FO2 A;  3SDR A;  2BRW A;  3S4D A;  1N95 B;  4L6X A;  1WU5 A;  1ULV A;  3D5S A;  1KRE A;  3E37 B;  1UMP A;  1S63 B;  2V8J A;  5GZK A;  3QT9 A;  3GT5 A;  3K11 A;  1XWQ A;  1GHQ A;  4WU0 A;  3Q75 B;  1O6H A;  4MU9 A;  4DI5 A;  1RWF A;  1GXN A;  3Q7A B;  3RX5 A;  5JMD A;  5KKB A;  3W5M A;  4AYR A;  2BRV X;  2H6G B;  2FUT A;  1N94 B;  1LXK A;  3ANK A;  3M7L A;  1UG9 A;  2RGK A;  4KTR A;  2WII B;  1SQC A;  3PZ1 B;  1DCE B;  5AGD A;  3RRS A;  1N4S B;  2XQW A;  1RWA A;  1NL4 B;  3M76 A;  1TNZ B;  3PYB A;  3QXF A;  4Z4J A;  4KKJ A;  4ZRQ A;  1RWH A;  3VSM A;  1GAH A;  4FUS A;  1JCS B;  2BBC A;  3A3V A;  1I8Q A;  4L9P B;  3S4B A;  3S4C A;  2NOJ A;  1W6K A;  4YCR A;  1O1S B;  3S9V A;  1L2A A;  1FO3 A;  4DOE A;  1HMU A;  1WZZ A;  2Z07 A;  5FOB B;  2FUQ A;  2ZZR A;  5DHK A;  4DOD A;  5EAT A;  5ILD A;  4AYQ A;  3Q7F B;  1HM3 A;  1N4Q B;  2JG0 A;  2ZBL A;  2PMV A;  4WVA A;  1XW2 A;  1MZC B;  3H3K A;  3EU8 A;  1FMI A;  1JCQ B;  3M01 A;  1XWT A;  1LOH A;  4J5T A;  1TF4 A;  3ANI A;  2ONH A;  2FV0 A;  3WC3 A;  1HM2 A;  1HXG A;  2YIK A;  5CD2 A;  1WU4 A;  2OKX A;  5ILI A;  4GTR B;  1C3D A;  4D4D A;  3QWT A;  5ILJ A;  2ONG A;  5FO8 B;  1N4R B;  1GXM A;  1HX9 A;  3Q79 B;  1HCU A;  1F9D A;  1HXC A;  4EL8 A;  3M02 A;  2EAE A;  1O5M B;  1TNO B;  1G87 A;  1HZF A;  1OJO A;  1X81 B;  3SFY B;  1W6J A;  4KKI A;  2BB6 A;  4V1S A;  1DL2 A;  2JJB A;  3M72 A;  4BOK A;  3M78 A;  2XWB B;  3ACT A;  3W7W A;  1JCR B;  1FT1 B;  1KWF A;  3DST B;  3E80 A;  4WVC A;  1H37 A;  4AYP A;  5IK6 A;  5IKA A;  1QAZ A;  4MMH A;  3T33 A;  2B39 A;  2B4F A;  1K72 A;  1FCE A;  2RI8 A;  3WIQ A;  4GTV B;  5DGQ A;  3DSU B;  5DGR A;  3W7U A;  3E34 B;  3GLY A;  2XFG A;  1AGM A;  2DRQ A;  1X1H A;  5M7Y A;  3WIR A;  3RX8 A;  3W5N A;  3M77 A; 
#chains in the Genus database with same CATH homology
 1LTX B;  1H3B A;  4ZH1 A;  1DOG A;  1FP3 A;  1TNU B;  2A8Z A;  3SDU A;  1D8E B;  3ANJ A;  3M7E A;  1GXO A;  3E6U A;  2BB5 A;  1KZO B;  3SFX B;  3KSL B;  3WKG A;  1FPP B;  2H6H B;  1LF9 A;  2ZIS B;  3VXD A;  2ZIR B;  5CA3 A;  4CJ0 A;  3SDQ A;  5MEH A;  3KLS A;  2D8L A;  2XWJ B;  3M7B A;  3X17 A;  1H12 A;  1S64 B;  1O6Q A;  2VN4 A;  2RI9 A;  1O6R A;  2CQT A;  1H39 A;  2V8I A;  4Q2B A;  1QQF A;  3E73 A;  3KSQ B;  4LNV A;  2R2L B;  1GLM A;  3SDT A;  3SQC A;  4BOJ A;  1LD8 B;  3KQ4 A;  3M71 A;  3Q73 B;  1IA6 A;  2I07 B;  5JPN B;  3W7T A;  2G02 A;  3QPF A;  3H7L A;  4ZH5 A;  1VD5 A;  3HXC B;  4C1S A;  3S4A A;  3RX7 A;  1KFG A;  2QNO A;  2FV1 A;  4GTO B;  4GTQ B;  3PYA A;  4FXK B;  3QDE A;  1TNB B;  1TN6 B;  3WIW A;  4JJJ A;  2EAB A;  2GH4 A;  1V7V A;  3QG0 A;  1G6I A;  5JPM B;  3W7S A;  4D4C A;  2SQC A;  1L1Y A;  3PZ2 B;  2PN5 A;  3P5R A;  1KSD A;  1KS8 A;  5GW7 A;  1R76 A;  2GZ6 A;  3DSW B;  3CIH A;  1V5C A;  4L0G A;  1GSZ A;  1H36 A;  3K7X A;  1KSC A;  3E32 B;  3WUX A;  3HXF B;  3EZ8 A;  1X9D A;  4D4B A;  2WIN B;  3AFJ A;  1O1T B;  3M73 A;  5E2J A;  3DRA B;  3W7X A;  1V5D A;  4M76 A;  4LNG B;  1LF6 A;  4GL3 A;  1SA5 B;  4ZRP A;  1UT9 A;  2AHG A;  2D5J A;  4AYO A;  1GAI A;  4LNB B;  3PMM A;  2H6I B;  1CEM A;  1KKT A;  3DSV B;  3DPY B;  4MBG B;  3P2C A;  1G9G A;  2WY8 A;  2FBA A;  4TF4 A;  2JF4 A;  3PZ4 B;  3E33 B;  3TF4 A;  3RJ3 A;  1TN8 B;  1FBW A;  3DSS B;  3QFY A;  2V3N A;  1H3C A;  1D8D B;  1H54 A;  3G6J B;  1NC5 A;  3WKH A;  3H2W A;  3QT3 A;  2FUZ A;  2DRR A;  1G9J A;  2DRS A;  4LIX A;  2BED B;  4ONT A;  5M7I A;  1KRF A;  1QSJ A;  1TNY B;  1V7X A;  3GZK A;  2AFA A;  2F0Y B;  4Q88 A;  2CQS A;  1AYX A;  3P5P A;  3EU5 B;  1WU6 A;  1FT2 B;  4QT9 A;  1H14 A;  2H6F B;  4ZG8 A;  1QBQ B;  4GTM B;  2NVP A;  1IS9 A;  1N4P B;  1KZP B;  4CJ1 A;  5FO7 B;  4YDO B;  3EQA A;  3QFZ A;  1O79 A;  2WYN A;  1GA2 A;  2AHF A;  3SAE A;  1JS4 A;  1N9A B;  5CZL A;  2WY7 A;  3CU7 A;  2IEJ B;  3M7C A;  1NI1 B;  3QSP A;  3QRY A;  3SDV A;  1H3A A;  1NXC A;  1H35 A;  4KTP A;  1CLC A;  3M75 A;  2EAD A;  1FAE A;  3EUV B;  1O1R B;  2VN7 A;  1RQ5 A;  1LD7 B;  3ON6 A;  1IA7 A;  3Q78 B;  2EAC A;  3REN A;  4WVB A;  3WKI A;  4YDE B;  3HXB B;  4D4A A;  3OED A;  4Z4L A;  3HXE B;  3VW5 A;  4FXG B;  3C72 B;  2DRO A;  3D5R A;  1SA4 B;  2A73 B;  1TN7 B;  3DSX B;  2V3P A;  3M74 A;  5FO9 B;  3QXQ A;  2G0D A;  3WKF A;  4TXT A;  3ACS A;  4CE7 A;  1H13 A;  4D94 A;  1V7W A;  2GOX A;  3D3I A;  4GTP B;  4V1R A;  4GTS B;  3OXU A;  2P0V A;  3RSY A;  1FBO A;  4XUV A;  5GY3 A;  3PZ3 B;  2F6D A;  4EHM B;  2V8K A;  1F9O A;  3HXD B;  4GTT B;  3E30 B;  1FO2 A;  3SDR A;  3S4D A;  1N95 B;  4L6X A;  1WU5 A;  1ULV A;  3D5S A;  1KRE A;  3E37 B;  1UMP A;  1S63 B;  2V8J A;  5GZK A;  3QT9 A;  3GT5 A;  3K11 A;  1XWQ A;  1GHQ A;  4WU0 A;  3Q75 B;  1O6H A;  4MU9 A;  1GXN A;  3Q7A B;  3RX5 A;  5KKB A;  3W5M A;  4AYR A;  2H6G B;  1N94 B;  3ANK A;  3M7L A;  1UG9 A;  2RGK A;  4KTR A;  2WII B;  1SQC A;  3PZ1 B;  1DCE B;  5AGD A;  3RRS A;  1N4S B;  2XQW A;  1NL4 B;  3M76 A;  1TNZ B;  3PYB A;  3QXF A;  4Z4J A;  4KKJ A;  4ZRQ A;  4FUS A;  1GAH A;  1JCS B;  3A3V A;  2BBC A;  4L9P B;  3S4B A;  3S4C A;  2NOJ A;  1W6K A;  4YCR A;  1O1S B;  3S9V A;  1L2A A;  1FO3 A;  4DOE A;  1WZZ A;  2Z07 A;  5FOB B;  2ZZR A;  4DOD A;  4AYQ A;  3Q7F B;  4WVA A;  1N4Q B;  2JG0 A;  2ZBL A;  2PMV A;  1XW2 A;  1MZC B;  3H3K A;  3EU8 A;  1FMI A;  1JCQ B;  1XWT A;  4J5T A;  1TF4 A;  3ANI A;  2FV0 A;  3WC3 A;  2YIK A;  5CD2 A;  1WU4 A;  2OKX A;  4GTR B;  1C3D A;  4D4D A;  3QWT A;  5FO8 B;  1N4R B;  1GXM A;  3Q79 B;  1HCU A;  1F9D A;  4EL8 A;  2EAE A;  1O5M B;  1TNO B;  1G87 A;  1HZF A;  1X81 B;  3SFY B;  1W6J A;  4KKI A;  2BB6 A;  4V1S A;  1DL2 A;  2JJB A;  3M72 A;  4BOK A;  3M78 A;  2XWB B;  3ACT A;  3W7W A;  1JCR B;  1FT1 B;  1KWF A;  3DST B;  4WVC A;  1H37 A;  4AYP A;  3T33 A;  2B39 A;  2B4F A;  1K72 A;  1FCE A;  2RI8 A;  3WIQ A;  4GTV B;  5DGQ A;  3DSU B;  5DGR A;  3W7U A;  3E34 B;  3GLY A;  2XFG A;  1AGM A;  2DRQ A;  3WIR A;  5M7Y A;  3RX8 A;  3W5N A;  3M77 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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