3E33B

Protein farnesyltransferase complexed with fpp and ethylenediamine scaffold inhibitor 7
Total Genus 152
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
152
sequence length
407
structure length
407
Chain Sequence
PVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Protein farnesyltransferase/geranylgeranyltransferase type-1
total genus 152
structure length 407
sequence length 407
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2008-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 3e33B00
2V8JA 3OXUA 4KKIA 1H3AA 3KSQB 4GTOB 4GTTB 5FOBB 1C3DA 2G02A 2H6FB 3HXDB 2PN5A 4GTSB 3SQCA 2NOJA 1N95B 1TNYB 1GXNA 4GTRB 3KLSA 3Q7AB 4LNBB 2XWBB 2IEJB 4YDEB 2V3NA 5JPNB 4ZH1A 4FXGB 3DRAB 1TN6B 4LNGB 5FO7B 1QQFA 4D4CA 4LNVA 2ZIRB 1QSJA 1N4RB 3Q78B 4MBGB 3PZ4B 4GTVB 4GTMB 3PZ1B 1KZOB 1TNBB 1O6RA 1SA5B 3KSLB 1D8DB 1N9AB 1TN8B 2WIIB 2B39A 3PZ2B 3HXEB 4GTQB 1W6JA 1GXOA 1H37A 3E34B 3EUVB 1SA4B 3DSWB 2A73B 2ZISB 3E32B 2SQCA 2WY8A 1R76A 1H39A 4BOJA 2F0YB 4YDOB 3SFYB 1O1TB 3C72B 4V1RA 5JPMB 4D4DA 1NL4B 1DCEB 2I07B 1NI1B 3Q79B 3DSUB 1GSZA 3CU7A 1H3BA 1H36A 1O6HA 1FT1B 1O1SB 2V3PA 4MU9A 4KKJA 4D94A 1TNOB 1GXMA 4M76A 1N4PB 3DPYB 1FPPB 3G6JB 4GTPB 2PMVA 1UMPA 3SFXB 4ZRQA 2BB6A 2WY7A 1O1RB 1SQCA 1S63B 3E37B 3OEDA 1LD8B 1O6QA 2BB5A 5FO8B 3D5RA 4BOKA 5AGDA 2G0DA 1H3CA 2WINB 4EHMB 3Q7FB 1TN7B 3E33B 1GHQA 1JCQB 1N4SB 1H35A 1TNZB 3DSSB 2XQWA 3E30B 3DSTB 2H6GB 4D4BA 1N4QB 3EU5B 2H6IB 1O5MB 3Q75B 5FO9B 1JCSB 3KQ4A 1FT2B 1MZCB 1W6KA 2V8KA 2XWJB 4ONTA 4C1SA 1N94B 3RJ3A 2GOXA 4V1SA 3HXCB 2H6HB 4D4AA 4L9PB 2BEDB 2BBCA 3PZ3B 3HXBB 1QBQB 4FXKB 1D8EB 1TNUB 1O79A 3D5SA 4ZRPA 1KZPB 1HZFA 3Q73B 2R2LB 3DSVB 1S64B 3DSXB 1LD7B 1LTXB 1X81B 3HXFB 3K7XA 2V8IA 1JCRB
chains in the Genus database with same CATH superfamily
4AYRA 1H3AA 3KSQB 5IK9A 2G02A 1N7PA 5GW7A 2NOJA 5ILZA 3W7WA 2A8ZA 3KLSA 5JPNB 3QSPA 1KFGA 3TF4A 1N20A 5ILYA 2FUQA 3QFYA 3M7CA 5FO7B 3ACSA 4LNVA 2ZIRB 4MBGB 1V7VA 4TXTA 1OJNA 3QT9A 5ILDA 2WDAA 1N9AB 2B39A 3M01A 4KTRA 1GLMA 2FUTA 3EUVB 1L2AA 2ZISB 3H2WA 5EASA 1X9DA 5GZKA 1H39A 3RRSA 1F1SA 3S4CA 4WU0A 4YDOB 1O1TB 4V1RA 4D4DA 1LOHA 1DCEB 1FO3A 1GSZA 3CU7A 1VD5A 3A3VA 1IA6A 3QG0A 4M76A 3DPYB 2AFAA 1UMPA 2BB6A 1GAHA 3G4FA 4F13A 2JJBA 3E37B 1O6QA 4E1YA 3AFLA 1AYXA 1X1IA 1GAIA 5AGDA 2JF4A 4Z4JA 1H54A 2VN7A 3Q7FB 1TN7B 3E33B 1KSCA 1GA2A 1H35A 3NFVA 3RX8A 2CQSA 5JMFA 2Q1FA 4MMHA 1LF6A 3E30B 3WIRA 3ACTA 1N4QB 3ON6A 1HM2A 1RW9A 1G6IA 4OJZA 3E73A 3Q75B 5DGQA 1G9JA 3WIQA 3CIHA 3RJ3A 4V1SA 2H6HB 3S4AA 3PZ3B 3AFJA 5CZLA 3QPFA 3WKGA 2DRQA 1O79A 1F9GA 1HZFA 4DODA 3DSVB 1N7QA 1X1HA 3W5MA 3W7UA 2FV0A 1KSDA 4ZG8A 3K7XA 3ANJA 3WC3A 3SDTA 3W5NA 2H6FB 2B4FA 2PN5A 1RQ5A 1HCUA 3PYBA 3SDVA 3EU8A 5C05A 4GTRB 3P2CA 4LNBB 3M02A 5DGRA 2VN4A 3P5RA 3SAEA 4FXGB 1FP3A 1I8QA 1QQFA 4D4CA 1N4RB 1OJOA 2XFGA 3PYAA 4GTMB 3M72A 1SA5B 3KSLB 2ZBLA 3VW5A 1W3YA 2WIIB 3PZ2B 4WVAA 3RENA 5ILJA 3E34B 3S4DA 2WY8A 2P0VA 1N1BA 3N0GA 2BRPA 4BOJA 1ULVA 2F0YB 4L0GA 3RX5A 1NL4B 2I07B 1NI1B 1TF4A 2FUZA 2EACA 1H3BA 1O6HA 2V3PA 1O1SB 5M7YA 1EGUA 4MU9A 1KS8A 4KKJA 2ONGA 2AHGA 1N4PB 1WU5A 1FPPB 2ZZRA 3G6JB 2PMVA 4QT9A 4CE7A 3M71A 3M78A 4ZRQA 2WY7A 4KTPA 3W7TA 1SQCA 5DHIA 1HMWA 1XWQA 3GZKA 2ONHA 3WIWA 3WKFA 1FAEA 4BOKA 3SDRA 3VXDA 1KRFA 3RX7A 4GAXA 1NC5A 4LIXA 5IK0A 4EHMB 2RI8A 4J5TA 4OZVA 1HXCA 1N4SB 1UT9A 2XQWA 4WVCA 3NNBA 3E7JA 2YIKA 3DSTB 2H6GB 3A0OA 3EU5B 3GLYA 3PMMA 3KQ4A 3QWTA 2D8LA 1MZCB 1W6KA 1XW2A 2V8KA 5ILHA 2GOXA 3HXCB 4L9PB 2BEDB 1RWCA 4MMIA 3M77A 3M73A 4AYQA 1QBQB 4FXKB 1H14A 1D8EB 2F6DA 4Z4LA 2EAEA 3D5SA 4ZRPA 1HV6A 1X81B 2V8IA 4KKIA 4AYOA 1LF9A 1WZZA 4GTOB 4CJ0A 3D3IA 5FOBB 1C3DA 4Q2BA 4DI5A 3RSYA 1N95B 5IKAA 1KKTA 2IEJB 2V3NA 4WVBA 4YDEB 3K11A 4ZH1A 1L1YA 2RI9A 3ANKA 3EQAA 4FUSA 5IL3A 4RNQA 1TN6B 4LNGB 1FCEA 1QSJA 2FV1A 1V7XA 4GTVB 3S4BA 2EADA 4NEIA 1J0MA 5IL8A 5CD2A 3T33A 1TNBB 1HM3A 2FBAA 1UG9A 3P5PA 1D8DB 1TN8B 4OK2A 1W6JA 5MEHA 1GXOA 1KREA 1SA4B 3DSWB 2A73B 5IKHA 1FBWA 1JS4A 1LXKA 3W7XA 3WKHA 1H13A 1RWAA 5DHKA 4FJQA 4F10A 3SFYB 3C72B 5JPMB 3Q79B 3DSUB 3SDQA 1FT1B 1CB8A 1TNOB 1GXMA 1HXAA 1V7WA 2DROA 5IM1A 1DL2A 1N24A 2DRSA 4GTPB 3SFXB 3WKIA 5JMDA 1FBOA 1S63B 4CJ1A 3M75A 3N0FA 2CQTA 3D5RA 3M7LA 5KKBA 3VSMA 1H12A 2G0DA 3M74A 5ILKA 5ILIA 1DOGA 4YCRA 3DSSB 3M7EA 3LZ9A 1FMIA 3M76A 1KWFA 1J0NA 2GZ6A 2H6IB 1JCSB 2EABA 2RGKA 3QDEA 1FT2B 2DRRA 1FO2A 2XWJB 5CA3A 1N94B 3ANIA 2Z07A 3GT5A 3VSNA 2JG0A 2BBCA 3X17A 3W7SA 3HXBB 1N21A 4JJJA 3E80A 1KZPB 1HXGA 3Q73B 1S64B 1CEMA 1N22A 2WCOA 3DSXB 4TF4A 2GH4A 3HXFB 1XWTA 1JCRB 2V8JA 3OXUA 2J5CA 4GTTB 5M7IA 3HXDB 4GTSB 2OKXA 3SQCA 4EL8A 1TNYB 3SDUA 1GXNA 3S9VA 5GY3A 3H7LA 3Q7AB 2XWBB 1X1JA 4GL3A 2BRVX 3DRAB 3QT3A 2D5JA 2WYNA 3Q78B 3PZ4B 1RWHA 2X03A 3PZ1B 1LXMA 5E2JA 1KZOB 1HMUA 1QAZA 1O6RA 1NXCA 2E24A 3HXEB 4GTQB 1H37A 3E6UA 3E32B 2SQCA 1R76A 1N7OA 1N23A 1V5CA 2QNOA 3QRYA 4Q88A 1HX9A 4L6XA 1H36A 4OK4A 1IA7A 5EATA 4D94A 1N7NA 4FNVA 1K72A 1RWGA 4XUVA 1V5DA 3H3KA 1OJPA 1O1RB 5IK6A 3OEDA 2AHFA 1LD8B 2BB5A 5FO8B 1WU4A 1H3CA 1N1ZA 2WINB 4AYPA 3M7BA 2E22A 1JCQB 1GHQA 2NVPA 1TNZB 3M00A 5EAUA 1RWFA 3QXFA 1IS9A 4D4BA 4OZWA 3WUXA 1O5MB 1F9DA 3EZ8A 5FO9B 1OJMA 1F9OA 1AGMA 4ONTA 4C1SA 4DOEA 3QXQA 1G9GA 4D4AA 3G4DA 1C82A 1CLCA 3QFZA 1G87A 1TNUB 2BRWA 4ZH5A 1N7RA 1WU6A 2R2LB 1LD7B 1LTXB 1HN0A
chains in the Genus database with same CATH topology
4AYRA 1H3AA 3KSQB 2G02A 5GW7A 2NOJA 3W7WA 2A8ZA 3KLSA 5JPNB 3QSPA 1KFGA 3TF4A 3QFYA 3M7CA 5FO7B 3ACSA 4LNVA 2ZIRB 4MBGB 1V7VA 4TXTA 3QT9A 1N9AB 2B39A 4KTRA 1GLMA 3EUVB 1L2AA 2ZISB 3H2WA 1X9DA 5GZKA 1H39A 3RRSA 3S4CA 4WU0A 4YDOB 1O1TB 4V1RA 4D4DA 1DCEB 1FO3A 1GSZA 3CU7A 1VD5A 3A3VA 1IA6A 3QG0A 4M76A 3DPYB 2AFAA 1UMPA 2BB6A 1GAHA 2JJBA 3E37B 1O6QA 1AYXA 1GAIA 5AGDA 2JF4A 4Z4JA 1H54A 2VN7A 3Q7FB 1TN7B 3E33B 1KSCA 1GA2A 1H35A 3RX8A 2CQSA 1LF6A 3E30B 3WIRA 3ACTA 1N4QB 3ON6A 1G6IA 3E73A 3Q75B 5DGQA 1G9JA 3WIQA 3CIHA 3RJ3A 4V1SA 2H6HB 3S4AA 3PZ3B 3AFJA 5CZLA 3QPFA 3WKGA 2DRQA 1O79A 1HZFA 4DODA 3DSVB 3W5MA 3W7UA 2FV0A 1KSDA 4ZG8A 3K7XA 3ANJA 3WC3A 3SDTA 3W5NA 2H6FB 2B4FA 2PN5A 1RQ5A 1HCUA 3PYBA 3SDVA 3EU8A 4GTRB 3P2CA 4LNBB 5DGRA 2VN4A 3P5RA 3SAEA 4FXGB 1FP3A 1QQFA 4D4CA 1N4RB 2XFGA 3PYAA 4GTMB 3M72A 1SA5B 3KSLB 2ZBLA 3VW5A 2WIIB 3PZ2B 4WVAA 3RENA 3E34B 3S4DA 2WY8A 2P0VA 4BOJA 1ULVA 2F0YB 4L0GA 3RX5A 1NL4B 2I07B 1NI1B 1TF4A 2FUZA 2EACA 1H3BA 1O6HA 2V3PA 1O1SB 5M7YA 4MU9A 1KS8A 4KKJA 2AHGA 1N4PB 1WU5A 1FPPB 2ZZRA 3G6JB 2PMVA 4QT9A 4CE7A 3M71A 3M78A 4ZRQA 2WY7A 4KTPA 3W7TA 1SQCA 1XWQA 3GZKA 3WIWA 3WKFA 1FAEA 4BOKA 3SDRA 3VXDA 1KRFA 3RX7A 1NC5A 4LIXA 4EHMB 2RI8A 4J5TA 1N4SB 1UT9A 2XQWA 4WVCA 2YIKA 3DSTB 2H6GB 3EU5B 3GLYA 3PMMA 3KQ4A 3QWTA 2D8LA 1MZCB 1W6KA 1XW2A 2V8KA 2GOXA 3HXCB 4L9PB 2BEDB 3M77A 3M73A 4AYQA 1QBQB 4FXKB 1H14A 1D8EB 2F6DA 4Z4LA 2EAEA 3D5SA 4ZRPA 1X81B 2V8IA 4KKIA 4AYOA 1LF9A 1WZZA 4GTOB 4CJ0A 3D3IA 5FOBB 1C3DA 4Q2BA 3RSYA 1N95B 1KKTA 2IEJB 2V3NA 4WVBA 4YDEB 3K11A 4ZH1A 1L1YA 2RI9A 3ANKA 3EQAA 4FUSA 1TN6B 4LNGB 1FCEA 1QSJA 2FV1A 1V7XA 4GTVB 3S4BA 2EADA 5CD2A 3T33A 1TNBB 2FBAA 1UG9A 3P5PA 1D8DB 1TN8B 1W6JA 5MEHA 1GXOA 1KREA 1SA4B 3DSWB 2A73B 3W7XA 1FBWA 1JS4A 3WKHA 1H13A 3SFYB 3C72B 5JPMB 3Q79B 3DSUB 3SDQA 1FT1B 1TNOB 1GXMA 1V7WA 2DROA 1DL2A 2DRSA 4GTPB 3SFXB 3WKIA 1FBOA 1S63B 4CJ1A 3M75A 2CQTA 3D5RA 3M7LA 5KKBA 1H12A 2G0DA 3M74A 1DOGA 4YCRA 3DSSB 3M7EA 1FMIA 3M76A 1KWFA 2GZ6A 2H6IB 1JCSB 2EABA 2RGKA 1FT2B 2DRRA 1FO2A 2XWJB 5CA3A 1N94B 3ANIA 2Z07A 3GT5A 2JG0A 2BBCA 3X17A 3W7SA 3HXBB 4JJJA 1KZPB 3Q73B 1S64B 1CEMA 3DSXB 4TF4A 2GH4A 3HXFB 1XWTA 1JCRB 2V8JA 3OXUA 4GTTB 5M7IA 3HXDB 4GTSB 2OKXA 3SQCA 4EL8A 1TNYB 3SDUA 1GXNA 3S9VA 5GY3A 3H7LA 3Q7AB 2XWBB 4GL3A 3DRAB 3QT3A 2D5JA 2WYNA 3Q78B 3PZ4B 3PZ1B 5E2JA 1KZOB 1O6RA 1NXCA 3HXEB 4GTQB 1H37A 3E6UA 3E32B 2SQCA 1R76A 1V5CA 2QNOA 3QRYA 4Q88A 4L6XA 1H36A 1IA7A 4D94A 1K72A 4XUVA 1V5DA 3H3KA 1O1RB 3OEDA 2AHFA 1LD8B 2BB5A 5FO8B 1WU4A 1H3CA 2WINB 4AYPA 3M7BA 1GHQA 1JCQB 2NVPA 1TNZB 3QXFA 1IS9A 4D4BA 3WUXA 1O5MB 1F9DA 3EZ8A 5FO9B 1F9OA 1AGMA 4ONTA 4C1SA 4DOEA 3QXQA 1G9GA 4D4AA 1CLCA 3QFZA 1G87A 1TNUB 4ZH5A 1WU6A 2R2LB 1LD7B 1LTXB 3QDEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V8J A;  3OXU A;  4KKI A;  1H3A A;  3KSQ B;  4GTO B;  4GTT B;  5FOB B;  1C3D A;  2G02 A;  2H6F B;  3HXD B;  2PN5 A;  4GTS B;  3SQC A;  2NOJ A;  1N95 B;  1TNY B;  1GXN A;  4GTR B;  3KLS A;  3Q7A B;  4LNB B;  2XWB B;  2IEJ B;  4YDE B;  2V3N A;  5JPN B;  4ZH1 A;  4FXG B;  3DRA B;  1TN6 B;  4LNG B;  5FO7 B;  1QQF A;  4D4C A;  4LNV A;  2ZIR B;  1QSJ A;  1N4R B;  3Q78 B;  4MBG B;  3PZ4 B;  4GTV B;  4GTM B;  3PZ1 B;  1KZO B;  1TNB B;  1O6R A;  1SA5 B;  3KSL B;  1D8D B;  1N9A B;  1TN8 B;  2WII B;  2B39 A;  3PZ2 B;  3HXE B;  4GTQ B;  1W6J A;  1GXO A;  1H37 A;  3E34 B;  3EUV B;  1SA4 B;  3DSW B;  2A73 B;  2ZIS B;  3E32 B;  2SQC A;  2WY8 A;  1R76 A;  1H39 A;  4BOJ A;  2F0Y B;  4YDO B;  3SFY B;  1O1T B;  3C72 B;  4V1R A;  5JPM B;  4D4D A;  1NL4 B;  1DCE B;  2I07 B;  1NI1 B;  3Q79 B;  3DSU B;  1GSZ A;  3CU7 A;  1H3B A;  1H36 A;  1O6H A;  1FT1 B;  1O1S B;  2V3P A;  4MU9 A;  4KKJ A;  4D94 A;  1TNO B;  1GXM A;  4M76 A;  1N4P B;  3DPY B;  1FPP B;  3G6J B;  4GTP B;  2PMV A;  1UMP A;  3SFX B;  4ZRQ A;  2BB6 A;  2WY7 A;  1O1R B;  1SQC A;  1S63 B;  3E37 B;  3OED A;  1LD8 B;  1O6Q A;  2BB5 A;  5FO8 B;  3D5R A;  4BOK A;  5AGD A;  2G0D A;  1H3C A;  2WIN B;  4EHM B;  3Q7F B;  1TN7 B;  3E33 B;  1GHQ A;  1JCQ B;  1N4S B;  1H35 A;  1TNZ B;  3DSS B;  2XQW A;  3E30 B;  3DST B;  2H6G B;  4D4B A;  1N4Q B;  3EU5 B;  2H6I B;  1O5M B;  3Q75 B;  5FO9 B;  1JCS B;  3KQ4 A;  1FT2 B;  1MZC B;  1W6K A;  2V8K A;  2XWJ B;  4ONT A;  4C1S A;  1N94 B;  3RJ3 A;  2GOX A;  4V1S A;  3HXC B;  2H6H B;  4D4A A;  4L9P B;  2BED B;  2BBC A;  3PZ3 B;  3HXB B;  1QBQ B;  4FXK B;  1D8E B;  1TNU B;  1O79 A;  3D5S A;  4ZRP A;  1KZP B;  1HZF A;  3Q73 B;  2R2L B;  3DSV B;  1S64 B;  3DSX B;  1LD7 B;  1LTX B;  1X81 B;  3HXF B;  3K7X A;  2V8I A;  1JCR B; 
#chains in the Genus database with same CATH topology
 4AYR A;  1H3A A;  3KSQ B;  5IK9 A;  2G02 A;  1N7P A;  5GW7 A;  2NOJ A;  5ILZ A;  3W7W A;  2A8Z A;  3KLS A;  5JPN B;  3QSP A;  1KFG A;  3TF4 A;  1N20 A;  5ILY A;  2FUQ A;  3QFY A;  3M7C A;  5FO7 B;  3ACS A;  4LNV A;  2ZIR B;  4MBG B;  1V7V A;  4TXT A;  1OJN A;  3QT9 A;  5ILD A;  2WDA A;  1N9A B;  2B39 A;  3M01 A;  4KTR A;  1GLM A;  2FUT A;  3EUV B;  1L2A A;  2ZIS B;  3H2W A;  5EAS A;  1X9D A;  5GZK A;  1H39 A;  3RRS A;  1F1S A;  3S4C A;  4WU0 A;  4YDO B;  1O1T B;  4V1R A;  4D4D A;  1LOH A;  1DCE B;  1FO3 A;  1GSZ A;  3CU7 A;  1VD5 A;  3A3V A;  1IA6 A;  3QG0 A;  4M76 A;  3DPY B;  2AFA A;  1UMP A;  2BB6 A;  1GAH A;  3G4F A;  4F13 A;  2JJB A;  3E37 B;  1O6Q A;  4E1Y A;  3AFL A;  1AYX A;  1X1I A;  1GAI A;  5AGD A;  2JF4 A;  4Z4J A;  1H54 A;  2VN7 A;  3Q7F B;  1TN7 B;  3E33 B;  1KSC A;  1GA2 A;  1H35 A;  3NFV A;  3RX8 A;  2CQS A;  5JMF A;  2Q1F A;  4MMH A;  1LF6 A;  3E30 B;  3WIR A;  3ACT A;  1N4Q B;  3ON6 A;  1HM2 A;  1RW9 A;  1G6I A;  4OJZ A;  3E73 A;  3Q75 B;  5DGQ A;  1G9J A;  3WIQ A;  3CIH A;  3RJ3 A;  4V1S A;  2H6H B;  3S4A A;  3PZ3 B;  3AFJ A;  5CZL A;  3QPF A;  3WKG A;  2DRQ A;  1O79 A;  1F9G A;  1HZF A;  4DOD A;  3DSV B;  1N7Q A;  1X1H A;  3W5M A;  3W7U A;  2FV0 A;  1KSD A;  4ZG8 A;  3K7X A;  3ANJ A;  3WC3 A;  3SDT A;  3W5N A;  2H6F B;  2B4F A;  2PN5 A;  1RQ5 A;  1HCU A;  3PYB A;  3SDV A;  3EU8 A;  5C05 A;  4GTR B;  3P2C A;  4LNB B;  3M02 A;  5DGR A;  2VN4 A;  3P5R A;  3SAE A;  4FXG B;  1FP3 A;  1I8Q A;  1QQF A;  4D4C A;  1N4R B;  1OJO A;  2XFG A;  3PYA A;  4GTM B;  3M72 A;  1SA5 B;  3KSL B;  2ZBL A;  3VW5 A;  1W3Y A;  2WII B;  3PZ2 B;  4WVA A;  3REN A;  5ILJ A;  3E34 B;  3S4D A;  2WY8 A;  2P0V A;  1N1B A;  3N0G A;  2BRP A;  4BOJ A;  1ULV A;  2F0Y B;  4L0G A;  3RX5 A;  1NL4 B;  2I07 B;  1NI1 B;  1TF4 A;  2FUZ A;  2EAC A;  1H3B A;  1O6H A;  2V3P A;  1O1S B;  5M7Y A;  1EGU A;  4MU9 A;  1KS8 A;  4KKJ A;  2ONG A;  2AHG A;  1N4P B;  1WU5 A;  1FPP B;  2ZZR A;  3G6J B;  2PMV A;  4QT9 A;  4CE7 A;  3M71 A;  3M78 A;  4ZRQ A;  2WY7 A;  4KTP A;  3W7T A;  1SQC A;  5DHI A;  1HMW A;  1XWQ A;  3GZK A;  2ONH A;  3WIW A;  3WKF A;  1FAE A;  4BOK A;  3SDR A;  3VXD A;  1KRF A;  3RX7 A;  4GAX A;  1NC5 A;  4LIX A;  5IK0 A;  4EHM B;  2RI8 A;  4J5T A;  4OZV A;  1HXC A;  1N4S B;  1UT9 A;  2XQW A;  4WVC A;  3NNB A;  3E7J A;  2YIK A;  3DST B;  2H6G B;  3A0O A;  3EU5 B;  3GLY A;  3PMM A;  3KQ4 A;  3QWT A;  2D8L A;  1MZC B;  1W6K A;  1XW2 A;  2V8K A;  5ILH A;  2GOX A;  3HXC B;  4L9P B;  2BED B;  1RWC A;  4MMI A;  3M77 A;  3M73 A;  4AYQ A;  1QBQ B;  4FXK B;  1H14 A;  1D8E B;  2F6D A;  4Z4L A;  2EAE A;  3D5S A;  4ZRP A;  1HV6 A;  1X81 B;  2V8I A;  4KKI A;  4AYO A;  1LF9 A;  1WZZ A;  4GTO B;  4CJ0 A;  3D3I A;  5FOB B;  1C3D A;  4Q2B A;  4DI5 A;  3RSY A;  1N95 B;  5IKA A;  1KKT A;  2IEJ B;  2V3N A;  4WVB A;  4YDE B;  3K11 A;  4ZH1 A;  1L1Y A;  2RI9 A;  3ANK A;  3EQA A;  4FUS A;  5IL3 A;  4RNQ A;  1TN6 B;  4LNG B;  1FCE A;  1QSJ A;  2FV1 A;  1V7X A;  4GTV B;  3S4B A;  2EAD A;  4NEI A;  1J0M A;  5IL8 A;  5CD2 A;  3T33 A;  1TNB B;  1HM3 A;  2FBA A;  1UG9 A;  3P5P A;  1D8D B;  1TN8 B;  4OK2 A;  1W6J A;  5MEH A;  1GXO A;  1KRE A;  1SA4 B;  3DSW B;  2A73 B;  5IKH A;  1FBW A;  1JS4 A;  1LXK A;  3W7X A;  3WKH A;  1H13 A;  1RWA A;  5DHK A;  4FJQ A;  4F10 A;  3SFY B;  3C72 B;  5JPM B;  3Q79 B;  3DSU B;  3SDQ A;  1FT1 B;  1CB8 A;  1TNO B;  1GXM A;  1HXA A;  1V7W A;  2DRO A;  5IM1 A;  1DL2 A;  1N24 A;  2DRS A;  4GTP B;  3SFX B;  3WKI A;  5JMD A;  1FBO A;  1S63 B;  4CJ1 A;  3M75 A;  3N0F A;  2CQT A;  3D5R A;  3M7L A;  5KKB A;  3VSM A;  1H12 A;  2G0D A;  3M74 A;  5ILK A;  5ILI A;  1DOG A;  4YCR A;  3DSS B;  3M7E A;  3LZ9 A;  1FMI A;  3M76 A;  1KWF A;  1J0N A;  2GZ6 A;  2H6I B;  1JCS B;  2EAB A;  2RGK A;  3QDE A;  1FT2 B;  2DRR A;  1FO2 A;  2XWJ B;  5CA3 A;  1N94 B;  3ANI A;  2Z07 A;  3GT5 A;  3VSN A;  2JG0 A;  2BBC A;  3X17 A;  3W7S A;  3HXB B;  1N21 A;  4JJJ A;  3E80 A;  1KZP B;  1HXG A;  3Q73 B;  1S64 B;  1CEM A;  1N22 A;  2WCO A;  3DSX B;  4TF4 A;  2GH4 A;  3HXF B;  1XWT A;  1JCR B;  2V8J A;  3OXU A;  2J5C A;  4GTT B;  5M7I A;  3HXD B;  4GTS B;  2OKX A;  3SQC A;  4EL8 A;  1TNY B;  3SDU A;  1GXN A;  3S9V A;  5GY3 A;  3H7L A;  3Q7A B;  2XWB B;  1X1J A;  4GL3 A;  2BRV X;  3DRA B;  3QT3 A;  2D5J A;  2WYN A;  3Q78 B;  3PZ4 B;  1RWH A;  2X03 A;  3PZ1 B;  1LXM A;  5E2J A;  1KZO B;  1HMU A;  1QAZ A;  1O6R A;  1NXC A;  2E24 A;  3HXE B;  4GTQ B;  1H37 A;  3E6U A;  3E32 B;  2SQC A;  1R76 A;  1N7O A;  1N23 A;  1V5C A;  2QNO A;  3QRY A;  4Q88 A;  1HX9 A;  4L6X A;  1H36 A;  4OK4 A;  1IA7 A;  5EAT A;  4D94 A;  1N7N A;  4FNV A;  1K72 A;  1RWG A;  4XUV A;  1V5D A;  3H3K A;  1OJP A;  1O1R B;  5IK6 A;  3OED A;  2AHF A;  1LD8 B;  2BB5 A;  5FO8 B;  1WU4 A;  1H3C A;  1N1Z A;  2WIN B;  4AYP A;  3M7B A;  2E22 A;  1JCQ B;  1GHQ A;  2NVP A;  1TNZ B;  3M00 A;  5EAU A;  1RWF A;  3QXF A;  1IS9 A;  4D4B A;  4OZW A;  3WUX A;  1O5M B;  1F9D A;  3EZ8 A;  5FO9 B;  1OJM A;  1F9O A;  1AGM A;  4ONT A;  4C1S A;  4DOE A;  3QXQ A;  1G9G A;  4D4A A;  3G4D A;  1C82 A;  1CLC A;  3QFZ A;  1G87 A;  1TNU B;  2BRW A;  4ZH5 A;  1N7R A;  1WU6 A;  2R2L B;  1LD7 B;  1LTX B;  1HN0 A; 
#chains in the Genus database with same CATH homology
 4AYR A;  1H3A A;  3KSQ B;  2G02 A;  5GW7 A;  2NOJ A;  3W7W A;  2A8Z A;  3KLS A;  5JPN B;  3QSP A;  1KFG A;  3TF4 A;  3QFY A;  3M7C A;  5FO7 B;  3ACS A;  4LNV A;  2ZIR B;  4MBG B;  1V7V A;  4TXT A;  3QT9 A;  1N9A B;  2B39 A;  4KTR A;  1GLM A;  3EUV B;  1L2A A;  2ZIS B;  3H2W A;  1X9D A;  5GZK A;  1H39 A;  3RRS A;  3S4C A;  4WU0 A;  4YDO B;  1O1T B;  4V1R A;  4D4D A;  1DCE B;  1FO3 A;  1GSZ A;  3CU7 A;  1VD5 A;  3A3V A;  1IA6 A;  3QG0 A;  4M76 A;  3DPY B;  2AFA A;  1UMP A;  2BB6 A;  1GAH A;  2JJB A;  3E37 B;  1O6Q A;  1AYX A;  1GAI A;  5AGD A;  2JF4 A;  4Z4J A;  1H54 A;  2VN7 A;  3Q7F B;  1TN7 B;  3E33 B;  1KSC A;  1GA2 A;  1H35 A;  3RX8 A;  2CQS A;  1LF6 A;  3E30 B;  3WIR A;  3ACT A;  1N4Q B;  3ON6 A;  1G6I A;  3E73 A;  3Q75 B;  5DGQ A;  1G9J A;  3WIQ A;  3CIH A;  3RJ3 A;  4V1S A;  2H6H B;  3S4A A;  3PZ3 B;  3AFJ A;  5CZL A;  3QPF A;  3WKG A;  2DRQ A;  1O79 A;  1HZF A;  4DOD A;  3DSV B;  3W5M A;  3W7U A;  2FV0 A;  1KSD A;  4ZG8 A;  3K7X A;  3ANJ A;  3WC3 A;  3SDT A;  3W5N A;  2H6F B;  2B4F A;  2PN5 A;  1RQ5 A;  1HCU A;  3PYB A;  3SDV A;  3EU8 A;  4GTR B;  3P2C A;  4LNB B;  5DGR A;  2VN4 A;  3P5R A;  3SAE A;  4FXG B;  1FP3 A;  1QQF A;  4D4C A;  1N4R B;  2XFG A;  3PYA A;  4GTM B;  3M72 A;  1SA5 B;  3KSL B;  2ZBL A;  3VW5 A;  2WII B;  3PZ2 B;  4WVA A;  3REN A;  3E34 B;  3S4D A;  2WY8 A;  2P0V A;  4BOJ A;  1ULV A;  2F0Y B;  4L0G A;  3RX5 A;  1NL4 B;  2I07 B;  1NI1 B;  1TF4 A;  2FUZ A;  2EAC A;  1H3B A;  1O6H A;  2V3P A;  1O1S B;  5M7Y A;  4MU9 A;  1KS8 A;  4KKJ A;  2AHG A;  1N4P B;  1WU5 A;  1FPP B;  2ZZR A;  3G6J B;  2PMV A;  4QT9 A;  4CE7 A;  3M71 A;  3M78 A;  4ZRQ A;  2WY7 A;  4KTP A;  3W7T A;  1SQC A;  1XWQ A;  3GZK A;  3WIW A;  3WKF A;  1FAE A;  4BOK A;  3SDR A;  3VXD A;  1KRF A;  3RX7 A;  1NC5 A;  4LIX A;  4EHM B;  2RI8 A;  4J5T A;  1N4S B;  1UT9 A;  2XQW A;  4WVC A;  2YIK A;  3DST B;  2H6G B;  3EU5 B;  3GLY A;  3PMM A;  3KQ4 A;  3QWT A;  2D8L A;  1MZC B;  1W6K A;  1XW2 A;  2V8K A;  2GOX A;  3HXC B;  4L9P B;  2BED B;  3M77 A;  3M73 A;  4AYQ A;  1QBQ B;  4FXK B;  1H14 A;  1D8E B;  2F6D A;  4Z4L A;  2EAE A;  3D5S A;  4ZRP A;  1X81 B;  2V8I A;  4KKI A;  4AYO A;  1LF9 A;  1WZZ A;  4GTO B;  4CJ0 A;  3D3I A;  5FOB B;  1C3D A;  4Q2B A;  3RSY A;  1N95 B;  1KKT A;  2IEJ B;  2V3N A;  4WVB A;  4YDE B;  3K11 A;  4ZH1 A;  1L1Y A;  2RI9 A;  3ANK A;  3EQA A;  4FUS A;  1TN6 B;  4LNG B;  1FCE A;  1QSJ A;  2FV1 A;  1V7X A;  4GTV B;  3S4B A;  2EAD A;  5CD2 A;  3T33 A;  1TNB B;  2FBA A;  1UG9 A;  3P5P A;  1D8D B;  1TN8 B;  1W6J A;  5MEH A;  1GXO A;  1KRE A;  1SA4 B;  3DSW B;  2A73 B;  3W7X A;  1FBW A;  1JS4 A;  3WKH A;  1H13 A;  3SFY B;  3C72 B;  5JPM B;  3Q79 B;  3DSU B;  3SDQ A;  1FT1 B;  1TNO B;  1GXM A;  1V7W A;  2DRO A;  1DL2 A;  2DRS A;  4GTP B;  3SFX B;  3WKI A;  1FBO A;  1S63 B;  4CJ1 A;  3M75 A;  2CQT A;  3D5R A;  3M7L A;  5KKB A;  1H12 A;  2G0D A;  3M74 A;  1DOG A;  4YCR A;  3DSS B;  3M7E A;  1FMI A;  3M76 A;  1KWF A;  2GZ6 A;  2H6I B;  1JCS B;  2EAB A;  2RGK A;  1FT2 B;  2DRR A;  1FO2 A;  2XWJ B;  5CA3 A;  1N94 B;  3ANI A;  2Z07 A;  3GT5 A;  2JG0 A;  2BBC A;  3X17 A;  3W7S A;  3HXB B;  4JJJ A;  1KZP B;  3Q73 B;  1S64 B;  1CEM A;  3DSX B;  4TF4 A;  2GH4 A;  3HXF B;  1XWT A;  1JCR B;  2V8J A;  3OXU A;  4GTT B;  5M7I A;  3HXD B;  4GTS B;  2OKX A;  3SQC A;  4EL8 A;  1TNY B;  3SDU A;  1GXN A;  3S9V A;  5GY3 A;  3H7L A;  3Q7A B;  2XWB B;  4GL3 A;  3DRA B;  3QT3 A;  2D5J A;  2WYN A;  3Q78 B;  3PZ4 B;  3PZ1 B;  5E2J A;  1KZO B;  1O6R A;  1NXC A;  3HXE B;  4GTQ B;  1H37 A;  3E6U A;  3E32 B;  2SQC A;  1R76 A;  1V5C A;  2QNO A;  3QRY A;  4Q88 A;  4L6X A;  1H36 A;  1IA7 A;  4D94 A;  1K72 A;  4XUV A;  1V5D A;  3H3K A;  1O1R B;  3OED A;  2AHF A;  1LD8 B;  2BB5 A;  5FO8 B;  1WU4 A;  1H3C A;  2WIN B;  4AYP A;  3M7B A;  1GHQ A;  1JCQ B;  2NVP A;  1TNZ B;  3QXF A;  1IS9 A;  4D4B A;  3WUX A;  1O5M B;  1F9D A;  3EZ8 A;  5FO9 B;  1F9O A;  1AGM A;  4ONT A;  4C1S A;  4DOE A;  3QXQ A;  1G9G A;  4D4A A;  1CLC A;  3QFZ A;  1G87 A;  1TNU B;  4ZH5 A;  1WU6 A;  2R2L B;  1LD7 B;  1LTX B;  3QDE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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