3KSQB

Discovery of c-imidazole azaheptapyridine fpt inhibitors
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
403
structure length
403
Chain Sequence
EPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPDGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYNVINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVMGVPENVLQPTHPVYNIGPDKVIQATTHFLQKPVPGF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of C-imidazole azaheptapyridine FPT inhibitors.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Farnesyltransferase, CAAX box, alpha
total genus 148
structure length 403
sequence length 403
ec nomenclature ec 2.5.1.58: Protein farnesyltransferase.
pdb deposition date 2009-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00432 Prenyltrans Prenyltransferase and squalene oxidase repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.20 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Glycosyltransferase 3ksqB00
3C72B 1D8EB 4GTRB 1LD7B 3D5SA 3Q75B 1NI1B 1C3DA 2BB5A 2WIIB 2B39A 4ONTA 1H36A 1N4QB 3Q78B 4ZRPA 1O1RB 1H39A 3EUVB 1N4SB 4V1RA 2H6HB 3PZ3B 3HXCB 2V8IA 3DSXB 1SA4B 4GTMB 2R2LB 4GTTB 3E37B 2H6FB 4BOJA 3SQCA 3E30B 1KZPB 2GOXA 3HXFB 4LNBB 3DSVB 1JCRB 3HXDB 1GXNA 1S64B 3KSLB 1TNOB 1O5MB 1H3CA 3DSTB 1N94B 3K7XA 4MBGB 4ZRQA 1N4PB 4MU9A 1FPPB 4EHMB 1LTXB 2V3PA 3PZ1B 1D8DB 5FO7B 4D4DA 2PN5A 2I07B 3Q73B 4M76A 1TNBB 1O79A 3Q7FB 3RJ3A 3KLSA 1SA5B 1GSZA 2WY8A 4ZH1A 1MZCB 2V3NA 3DRAB 5FO9B 3E32B 1H3BA 1HZFA 2XWBB 1FT1B 5AGDA 1GHQA 1N9AB 4V1SA 2ZISB 4GTSB 5JPNB 2NOJA 4D4CA 3PZ4B 3Q7AB 2V8KA 4D4BA 3Q79B 4KKJA 1GXOA 1TN6B 2BEDB 3SFXB 1TNZB 1UMPA 4BOKA 2XQWA 3DSSB 3PZ2B 1LD8B 4FXKB 3OEDA 3DPYB 1H35A 3SFYB 4YDOB 4LNGB 4C1SA 1O6RA 1H3AA 1SQCA 2XWJB 3G6JB 2A73B 2G0DA 2H6GB 1JCQB 1S63B 2WY7A 3KSQB 3E34B 1QQFA 1W6JA 2ZIRB 2PMVA 4GTVB 3OXUA 1TNUB 5JPMB 3HXBB 1QBQB 3DSWB 1GXMA 4GTOB 4GTQB 2IEJB 3D5RA 1TN8B 1TN7B 4LNVA 4GTPB 2SQCA 1R76A 1N95B 2BB6A 2G02A 4YDEB 3E33B 4L9PB 2V8JA 3CU7A 1O1SB 2BBCA 1NL4B 3KQ4A 1O6HA 4KKIA 1QSJA 2WINB 1W6KA 1X81B 4D4AA 2F0YB 4FXGB 1N4RB 3DSUB 5FOBB 5FO8B 1O1TB 4D94A 1O6QA 3EU5B 3HXEB 1JCSB 1KZOB 1FT2B 1TNYB 1DCEB 2H6IB 1H37A
chains in the Genus database with same CATH superfamily
1D8EB 1RQ5A 2QNOA 3D5SA 1HXGA 1AYXA 1DOGA 3S9VA 1H36A 2RI8A 3Q78B 3N0GA 1H39A 3EUVB 4V1RA 3W5NA 4YCRA 3PZ3B 1RWCA 2V8IA 1NC5A 4TXTA 4GTMB 1NXCA 4LIXA 5DGQA 4BOJA 3H3KA 1HX9A 3K11A 5DHKA 1KSDA 1N23A 1KREA 3E7JA 3LZ9A 3KSLB 4KTPA 3X17A 1WU4A 2VN4A 1UG9A 3DSTB 1N94B 1KWFA 2Q1FA 4GAXA 4ZRQA 3S4AA 3VSNA 4EHMB 2V3PA 2AFAA 1J0NA 4D4DA 3Q73B 1G6IA 1O79A 3E73A 3G4FA 3Q7FB 3RJ3A 2DRSA 4L0GA 4ZH1A 1GA2A 1OJOA 3E32B 1HM2A 1QAZA 2ONHA 4ZG8A 1N9AB 4J5TA 3SDQA 4KKJA 2BEDB 3WKGA 4EL8A 3QPFA 1HMUA 5ILZA 4OZVA 4OJZA 1V7XA 1KRFA 3SDTA 1LF9A 4YDOB 1O6RA 1F9OA 1H3AA 1SQCA 2A73B 3ANJA 3QDEA 3QRYA 1OJMA 2G0DA 4MMHA 2H6GB 1JCQB 1FAEA 2WY7A 5CZLA 1QQFA 3QFYA 1W6JA 2ZIRB 4GTVB 3WIWA 3WIQA 1DL2A 1QBQB 2DRQA 3D5RA 5IL3A 2ZZRA 2SQCA 3CIHA 4Z4JA 3M00A 4YDEB 4QT9A 3QT9A 4MMIA 3WUXA 3E33B 4L9PB 5M7IA 1O1SB 1UT9A 1NL4B 1QSJA 1W6KA 4D4AA 2F0YB 3SAEA 1RWAA 3RSYA 1CLCA 3DSUB 3T33A 3E6UA 4D94A 1JCSB 3M74A 1F9GA 1DCEB 1GAHA 2BRPA 1LD7B 2JG0A 3RX7A 3Q75B 2AHGA 2BB5A 5EASA 4Q88A 4GL3A 4DOEA 4ONTA 5GW7A 1N7PA 1N20A 2E24A 2H6HB 2EACA 3PYBA 3ON6A 2R2LB 3AFJA 3E37B 1CB8A 5ILYA 2AHFA 2J5CA 3E30B 3N0FA 3ANIA 4WVCA 3NNBA 2GOXA 3M02A 3HXFB 4KTRA 4LNBB 1JCRB 1EGUA 1GXNA 1RWFA 1HN0A 3NFVA 5CD2A 1KSCA 4MU9A 1FPPB 3WKIA 1LTXB 3PZ1B 1D8DB 4M76A 3EQAA 1TNBB 4JJJA 1XW2A 1H14A 2F6DA 1IS9A 1H3BA 2EADA 4Z4LA 3A3VA 1G9JA 3H7LA 3W7TA 2OKXA 2NOJA 4D4CA 3Q7AB 2V8KA 3M78A 2EAEA 3M7BA 2D8LA 3GT5A 4FNVA 2RGKA 5CA3A 2JJBA 4L6XA 1H35A 3SFYB 2XWJB 3EZ8A 3SDRA 1GLMA 1G87A 3M7LA 4NEIA 3TF4A 3KSQB 3E34B 2WCOA 4TF4A 5JPMB 3OXUA 2ZBLA 1RWHA 5GY3A 3DSWB 3GZKA 3WKHA 2GZ6A 1HXAA 4GTQB 4OK4A 3WKFA 2XFGA 1TN7B 4LNVA 4GTPB 1N95B 5IKHA 3W7WA 3G4DA 2G02A 4FUSA 2DRRA 2EABA 5JMDA 2V8JA 3P5PA 1O6HA 4KKIA 2RI9A 1N1BA 1X81B 1V7WA 1OJPA 5E2JA 3AFLA 1IA7A 3EU5B 3HXEB 1FO2A 1FT2B 3PYAA 1TNYB 1WZZA 4WVBA 4GTRB 5C05A 1X1JA 2D5JA 5ILHA 1C3DA 1G9GA 1FCEA 2DROA 2YIKA 1N4QB 4AYQA 3QXFA 3HXCB 2WYNA 1X1HA 2H6FB 3SQCA 1IA6A 1KZPB 1RW9A 3QWTA 3P2CA 3HXDB 4CE7A 1OJNA 1TNOB 2WDAA 3K7XA 3EU8A 4MBGB 3RX8A 1N4PB 3M73A 2FUZA 5FO7B 4DI5A 2PN5A 5ILDA 3QXQA 2I07B 3M01A 3KLSA 1SA5B 1GSZA 2WY8A 1HCUA 1MZCB 2V3NA 5FO9B 3W5MA 3WIRA 1N7NA 1GHQA 4V1SA 4GTSB 4CJ1A 1H12A 1VD5A 1N22A 3PZ4B 5IK9A 4WVAA 3Q79B 1GXOA 5DHIA 3SFXB 4ZH5A 1HV6A 1TNZB 4FJQA 1RWGA 1UMPA 4BOKA 2XQWA 1LD8B 2FBAA 4XUVA 4FXKB 3DPYB 2BRWA 1X1IA 1WU5A 4C1SA 4E1YA 4F13A 3G6JB 3QG0A 5IL8A 2FV1A 2CQTA 1LXKA 5EAUA 3W7UA 1TNUB 3H2WA 1LXMA 1HXCA 4GTOB 4AYOA 1N7QA 2ONGA 1TN8B 1XWTA 1ULVA 5ILJA 1LF6A 1N24A 3ACTA 1HMWA 2VN7A 1C82A 1N7OA 2GH4A 1FBWA 5IKAA 1N1ZA 4CJ0A 4OZWA 5ILIA 1V5CA 3VW5A 3W7SA 1HM3A 1N4RB 3PMMA 5FOBB 1O1TB 1FBOA 1GAIA 4AYPA 4Q2BA 4F10A 1KZOB 1F1SA 3E80A 3ANKA 2H6IB 2A8ZA 1FO3A 1H37A 3C72B 3VSMA 5IK6A 3P5RA 5MEHA 1KFGA 1J0MA 2FUQA 1NI1B 3M71A 3QFZA 2WIIB 2B39A 3SDVA 2E22A 2NVPA 4ZRPA 1O1RB 1N4SB 3A0OA 2X03A 4OK2A 3DSXB 1SA4B 4GTTB 1CEMA 5GZKA 3GLYA 3DSVB 1S64B 3QT3A 3RX5A 1O5MB 1H3CA 2B4FA 3VXDA 1LOHA 3S4DA 2Z07A 3QSPA 3DRAB 1JS4A 3ACSA 5JMFA 1HZFA 2XWBB 1FT1B 5AGDA 3SDUA 5KKBA 1XWQA 3RRSA 2ZISB 5JPNB 1I8QA 1N7RA 5DGRA 4D4BA 5EATA 5M7YA 1TN6B 2CQSA 3M72A 4DODA 1TF4A 3S4BA 3DSSB 3PZ2B 1F9DA 1KS8A 1V5DA 3OEDA 4RNQA 1AGMA 2FUTA 4LNGB 2P0VA 2BRVX 2JF4A 1V7VA 1H13A 1KKTA 4AYRA 1S63B 3WC3A 2PMVA 5IK0A 3M7EA 3S4CA 3HXBB 3M76A 4WU0A 1K72A 1GXMA 5IM1A 2IEJB 1FP3A 3RENA 3D3IA 1N21A 1X9DA 1R76A 1WU6A 1H54A 2BB6A 3M7CA 1W3YA 3CU7A 3KQ4A 2BBCA 3M77A 1FMIA 5ILKA 1L1YA 2FV0A 2WINB 3W7XA 4FXGB 5FO8B 3M75A 1O6QA 1L2AA
chains in the Genus database with same CATH topology
1D8EB 1RQ5A 2QNOA 3D5SA 1AYXA 1DOGA 3S9VA 1H36A 2RI8A 3Q78B 1H39A 3EUVB 4V1RA 3W5NA 4YCRA 3PZ3B 2V8IA 1NC5A 4TXTA 4GTMB 1NXCA 4LIXA 5DGQA 4BOJA 3H3KA 3K11A 1KSDA 1KREA 3KSLB 4KTPA 3X17A 1WU4A 2VN4A 1UG9A 3DSTB 1N94B 1KWFA 4ZRQA 3S4AA 4EHMB 2V3PA 2AFAA 4D4DA 3Q73B 1G6IA 1O79A 3E73A 3Q7FB 3RJ3A 2DRSA 4L0GA 4ZH1A 1GA2A 3E32B 4ZG8A 1N9AB 4J5TA 3SDQA 4KKJA 2BEDB 3WKGA 4EL8A 3QPFA 1V7XA 1KRFA 3SDTA 1LF9A 4YDOB 1O6RA 1F9OA 1H3AA 1SQCA 2A73B 3ANJA 3QDEA 3QRYA 2G0DA 2H6GB 1JCQB 1FAEA 2WY7A 5CZLA 1QQFA 3QFYA 1W6JA 2ZIRB 4GTVB 3WIWA 3WIQA 1DL2A 1QBQB 2DRQA 3D5RA 2ZZRA 2SQCA 3CIHA 4Z4JA 4YDEB 4QT9A 3QT9A 3WUXA 3E33B 4L9PB 5M7IA 1O1SB 1UT9A 1NL4B 1QSJA 1W6KA 4D4AA 2F0YB 3SAEA 3RSYA 1CLCA 3DSUB 3T33A 3E6UA 4D94A 1JCSB 3M74A 1DCEB 1GAHA 1LD7B 2JG0A 3RX7A 3Q75B 2AHGA 2BB5A 4Q88A 4GL3A 4DOEA 4ONTA 5GW7A 2H6HB 2EACA 3PYBA 3ON6A 2R2LB 3AFJA 3E37B 2AHFA 4WVCA 3E30B 3ANIA 2GOXA 3HXFB 4KTRA 4LNBB 1JCRB 1GXNA 5CD2A 1KSCA 4MU9A 1FPPB 3WKIA 1LTXB 3PZ1B 1D8DB 4M76A 3EQAA 1TNBB 4JJJA 1XW2A 1H14A 2F6DA 1IS9A 1H3BA 2EADA 4Z4LA 3A3VA 1G9JA 3H7LA 3W7TA 2OKXA 2NOJA 4D4CA 3Q7AB 2V8KA 3M78A 2EAEA 3M7BA 2D8LA 3GT5A 2RGKA 5CA3A 2JJBA 4L6XA 1H35A 3SFYB 2XWJB 3EZ8A 3SDRA 1GLMA 1G87A 3M7LA 3TF4A 3KSQB 3E34B 4TF4A 5JPMB 3OXUA 2ZBLA 5GY3A 3DSWB 3GZKA 3WKHA 2GZ6A 4GTQB 3WKFA 2XFGA 1TN7B 4LNVA 4GTPB 1N95B 3W7WA 2G02A 4FUSA 2DRRA 2EABA 2V8JA 3P5PA 1O6HA 4KKIA 2RI9A 1X81B 1V7WA 5E2JA 1IA7A 3EU5B 3HXEB 1FO2A 1FT2B 3PYAA 1TNYB 1WZZA 4WVBA 4GTRB 2D5JA 1C3DA 1G9GA 1FCEA 2DROA 2YIKA 1N4QB 4AYQA 3QXFA 3HXCB 2WYNA 2H6FB 3SQCA 1IA6A 1KZPB 3QWTA 3P2CA 3HXDB 4CE7A 1TNOB 3K7XA 3EU8A 4MBGB 3RX8A 1N4PB 3M73A 2FUZA 5FO7B 2PN5A 3QXQA 2I07B 3KLSA 1SA5B 1GSZA 2WY8A 1HCUA 1MZCB 2V3NA 5FO9B 3W5MA 3WIRA 1GHQA 4V1SA 4GTSB 4CJ1A 1H12A 1VD5A 3PZ4B 4WVAA 3Q79B 1GXOA 3SFXB 4ZH5A 1TNZB 1UMPA 4BOKA 2XQWA 1LD8B 2FBAA 4XUVA 4FXKB 3DPYB 1WU5A 4C1SA 3G6JB 3QG0A 2FV1A 2CQTA 3W7UA 1TNUB 3H2WA 4GTOB 4AYOA 1TN8B 1XWTA 1ULVA 1LF6A 3ACTA 2VN7A 2GH4A 1FBWA 4CJ0A 1V5CA 3VW5A 3W7SA 1N4RB 3PMMA 5FOBB 1O1TB 1FBOA 1GAIA 4AYPA 4Q2BA 1KZOB 3ANKA 2H6IB 2A8ZA 1FO3A 1H37A 3C72B 3P5RA 5MEHA 1KFGA 1NI1B 3M71A 3QFZA 2WIIB 2B39A 3SDVA 2NVPA 4ZRPA 1O1RB 1N4SB 3DSXB 1SA4B 4GTTB 1CEMA 5GZKA 3GLYA 3DSVB 1S64B 3QT3A 3RX5A 1O5MB 1H3CA 2B4FA 3VXDA 3S4DA 2Z07A 3QSPA 3DRAB 1JS4A 3ACSA 1HZFA 2XWBB 1FT1B 5AGDA 3SDUA 5KKBA 1XWQA 3RRSA 2ZISB 5JPNB 5DGRA 4D4BA 5M7YA 1TN6B 2CQSA 3M72A 4DODA 1TF4A 3S4BA 3DSSB 3PZ2B 1F9DA 1KS8A 1V5DA 3OEDA 1AGMA 4LNGB 2P0VA 2JF4A 1V7VA 1H13A 1KKTA 4AYRA 1S63B 3WC3A 2PMVA 3S4CA 3M7EA 3HXBB 3M76A 4WU0A 1GXMA 1K72A 2IEJB 1FP3A 3RENA 3D3IA 1X9DA 1R76A 1WU6A 1H54A 2BB6A 3M7CA 3CU7A 3KQ4A 2BBCA 3M77A 1FMIA 1L1YA 2FV0A 2WINB 3W7XA 4FXGB 5FO8B 3M75A 1O6QA 1L2AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C72 B;  1D8E B;  4GTR B;  1LD7 B;  3D5S A;  3Q75 B;  1NI1 B;  1C3D A;  2BB5 A;  2WII B;  2B39 A;  4ONT A;  1H36 A;  1N4Q B;  3Q78 B;  4ZRP A;  1O1R B;  1H39 A;  3EUV B;  1N4S B;  4V1R A;  2H6H B;  3PZ3 B;  3HXC B;  2V8I A;  3DSX B;  1SA4 B;  4GTM B;  2R2L B;  4GTT B;  3E37 B;  2H6F B;  4BOJ A;  3SQC A;  3E30 B;  1KZP B;  2GOX A;  3HXF B;  4LNB B;  3DSV B;  1JCR B;  3HXD B;  1GXN A;  1S64 B;  3KSL B;  1TNO B;  1O5M B;  1H3C A;  3DST B;  1N94 B;  3K7X A;  4MBG B;  4ZRQ A;  1N4P B;  4MU9 A;  1FPP B;  4EHM B;  1LTX B;  2V3P A;  3PZ1 B;  1D8D B;  5FO7 B;  4D4D A;  2PN5 A;  2I07 B;  3Q73 B;  4M76 A;  1TNB B;  1O79 A;  3Q7F B;  3RJ3 A;  3KLS A;  1SA5 B;  1GSZ A;  2WY8 A;  4ZH1 A;  1MZC B;  2V3N A;  3DRA B;  5FO9 B;  3E32 B;  1H3B A;  1HZF A;  2XWB B;  1FT1 B;  5AGD A;  1GHQ A;  1N9A B;  4V1S A;  2ZIS B;  4GTS B;  5JPN B;  2NOJ A;  4D4C A;  3PZ4 B;  3Q7A B;  2V8K A;  4D4B A;  3Q79 B;  4KKJ A;  1GXO A;  1TN6 B;  2BED B;  3SFX B;  1TNZ B;  1UMP A;  4BOK A;  2XQW A;  3DSS B;  3PZ2 B;  1LD8 B;  4FXK B;  3OED A;  3DPY B;  1H35 A;  3SFY B;  4YDO B;  4LNG B;  4C1S A;  1O6R A;  1H3A A;  1SQC A;  2XWJ B;  3G6J B;  2A73 B;  2G0D A;  2H6G B;  1JCQ B;  1S63 B;  2WY7 A;  3KSQ B;  3E34 B;  1QQF A;  1W6J A;  2ZIR B;  2PMV A;  4GTV B;  3OXU A;  1TNU B;  5JPM B;  3HXB B;  1QBQ B;  3DSW B;  1GXM A;  4GTO B;  4GTQ B;  2IEJ B;  3D5R A;  1TN8 B;  1TN7 B;  4LNV A;  4GTP B;  2SQC A;  1R76 A;  1N95 B;  2BB6 A;  2G02 A;  4YDE B;  3E33 B;  4L9P B;  2V8J A;  3CU7 A;  1O1S B;  2BBC A;  1NL4 B;  3KQ4 A;  1O6H A;  4KKI A;  1QSJ A;  2WIN B;  1W6K A;  1X81 B;  4D4A A;  2F0Y B;  4FXG B;  1N4R B;  3DSU B;  5FOB B;  5FO8 B;  1O1T B;  4D94 A;  1O6Q A;  3EU5 B;  3HXE B;  1JCS B;  1KZO B;  1FT2 B;  1TNY B;  1DCE B;  2H6I B;  1H37 A; 
#chains in the Genus database with same CATH topology
 1D8E B;  1RQ5 A;  2QNO A;  3D5S A;  1HXG A;  1AYX A;  1DOG A;  3S9V A;  1H36 A;  2RI8 A;  3Q78 B;  3N0G A;  1H39 A;  3EUV B;  4V1R A;  3W5N A;  4YCR A;  3PZ3 B;  1RWC A;  2V8I A;  1NC5 A;  4TXT A;  4GTM B;  1NXC A;  4LIX A;  5DGQ A;  4BOJ A;  3H3K A;  1HX9 A;  3K11 A;  5DHK A;  1KSD A;  1N23 A;  1KRE A;  3E7J A;  3LZ9 A;  3KSL B;  4KTP A;  3X17 A;  1WU4 A;  2VN4 A;  1UG9 A;  3DST B;  1N94 B;  1KWF A;  2Q1F A;  4GAX A;  4ZRQ A;  3S4A A;  3VSN A;  4EHM B;  2V3P A;  2AFA A;  1J0N A;  4D4D A;  3Q73 B;  1G6I A;  1O79 A;  3E73 A;  3G4F A;  3Q7F B;  3RJ3 A;  2DRS A;  4L0G A;  4ZH1 A;  1GA2 A;  1OJO A;  3E32 B;  1HM2 A;  1QAZ A;  2ONH A;  4ZG8 A;  1N9A B;  4J5T A;  3SDQ A;  4KKJ A;  2BED B;  3WKG A;  4EL8 A;  3QPF A;  1HMU A;  5ILZ A;  4OZV A;  4OJZ A;  1V7X A;  1KRF A;  3SDT A;  1LF9 A;  4YDO B;  1O6R A;  1F9O A;  1H3A A;  1SQC A;  2A73 B;  3ANJ A;  3QDE A;  3QRY A;  1OJM A;  2G0D A;  4MMH A;  2H6G B;  1JCQ B;  1FAE A;  2WY7 A;  5CZL A;  1QQF A;  3QFY A;  1W6J A;  2ZIR B;  4GTV B;  3WIW A;  3WIQ A;  1DL2 A;  1QBQ B;  2DRQ A;  3D5R A;  5IL3 A;  2ZZR A;  2SQC A;  3CIH A;  4Z4J A;  3M00 A;  4YDE B;  4QT9 A;  3QT9 A;  4MMI A;  3WUX A;  3E33 B;  4L9P B;  5M7I A;  1O1S B;  1UT9 A;  1NL4 B;  1QSJ A;  1W6K A;  4D4A A;  2F0Y B;  3SAE A;  1RWA A;  3RSY A;  1CLC A;  3DSU B;  3T33 A;  3E6U A;  4D94 A;  1JCS B;  3M74 A;  1F9G A;  1DCE B;  1GAH A;  2BRP A;  1LD7 B;  2JG0 A;  3RX7 A;  3Q75 B;  2AHG A;  2BB5 A;  5EAS A;  4Q88 A;  4GL3 A;  4DOE A;  4ONT A;  5GW7 A;  1N7P A;  1N20 A;  2E24 A;  2H6H B;  2EAC A;  3PYB A;  3ON6 A;  2R2L B;  3AFJ A;  3E37 B;  1CB8 A;  5ILY A;  2AHF A;  2J5C A;  3E30 B;  3N0F A;  3ANI A;  4WVC A;  3NNB A;  2GOX A;  3M02 A;  3HXF B;  4KTR A;  4LNB B;  1JCR B;  1EGU A;  1GXN A;  1RWF A;  1HN0 A;  3NFV A;  5CD2 A;  1KSC A;  4MU9 A;  1FPP B;  3WKI A;  1LTX B;  3PZ1 B;  1D8D B;  4M76 A;  3EQA A;  1TNB B;  4JJJ A;  1XW2 A;  1H14 A;  2F6D A;  1IS9 A;  1H3B A;  2EAD A;  4Z4L A;  3A3V A;  1G9J A;  3H7L A;  3W7T A;  2OKX A;  2NOJ A;  4D4C A;  3Q7A B;  2V8K A;  3M78 A;  2EAE A;  3M7B A;  2D8L A;  3GT5 A;  4FNV A;  2RGK A;  5CA3 A;  2JJB A;  4L6X A;  1H35 A;  3SFY B;  2XWJ B;  3EZ8 A;  3SDR A;  1GLM A;  1G87 A;  3M7L A;  4NEI A;  3TF4 A;  3KSQ B;  3E34 B;  2WCO A;  4TF4 A;  5JPM B;  3OXU A;  2ZBL A;  1RWH A;  5GY3 A;  3DSW B;  3GZK A;  3WKH A;  2GZ6 A;  1HXA A;  4GTQ B;  4OK4 A;  3WKF A;  2XFG A;  1TN7 B;  4LNV A;  4GTP B;  1N95 B;  5IKH A;  3W7W A;  3G4D A;  2G02 A;  4FUS A;  2DRR A;  2EAB A;  5JMD A;  2V8J A;  3P5P A;  1O6H A;  4KKI A;  2RI9 A;  1N1B A;  1X81 B;  1V7W A;  1OJP A;  5E2J A;  3AFL A;  1IA7 A;  3EU5 B;  3HXE B;  1FO2 A;  1FT2 B;  3PYA A;  1TNY B;  1WZZ A;  4WVB A;  4GTR B;  5C05 A;  1X1J A;  2D5J A;  5ILH A;  1C3D A;  1G9G A;  1FCE A;  2DRO A;  2YIK A;  1N4Q B;  4AYQ A;  3QXF A;  3HXC B;  2WYN A;  1X1H A;  2H6F B;  3SQC A;  1IA6 A;  1KZP B;  1RW9 A;  3QWT A;  3P2C A;  3HXD B;  4CE7 A;  1OJN A;  1TNO B;  2WDA A;  3K7X A;  3EU8 A;  4MBG B;  3RX8 A;  1N4P B;  3M73 A;  2FUZ A;  5FO7 B;  4DI5 A;  2PN5 A;  5ILD A;  3QXQ A;  2I07 B;  3M01 A;  3KLS A;  1SA5 B;  1GSZ A;  2WY8 A;  1HCU A;  1MZC B;  2V3N A;  5FO9 B;  3W5M A;  3WIR A;  1N7N A;  1GHQ A;  4V1S A;  4GTS B;  4CJ1 A;  1H12 A;  1VD5 A;  1N22 A;  3PZ4 B;  5IK9 A;  4WVA A;  3Q79 B;  1GXO A;  5DHI A;  3SFX B;  4ZH5 A;  1HV6 A;  1TNZ B;  4FJQ A;  1RWG A;  1UMP A;  4BOK A;  2XQW A;  1LD8 B;  2FBA A;  4XUV A;  4FXK B;  3DPY B;  2BRW A;  1X1I A;  1WU5 A;  4C1S A;  4E1Y A;  4F13 A;  3G6J B;  3QG0 A;  5IL8 A;  2FV1 A;  2CQT A;  1LXK A;  5EAU A;  3W7U A;  1TNU B;  3H2W A;  1LXM A;  1HXC A;  4GTO B;  4AYO A;  1N7Q A;  2ONG A;  1TN8 B;  1XWT A;  1ULV A;  5ILJ A;  1LF6 A;  1N24 A;  3ACT A;  1HMW A;  2VN7 A;  1C82 A;  1N7O A;  2GH4 A;  1FBW A;  5IKA A;  1N1Z A;  4CJ0 A;  4OZW A;  5ILI A;  1V5C A;  3VW5 A;  3W7S A;  1HM3 A;  1N4R B;  3PMM A;  5FOB B;  1O1T B;  1FBO A;  1GAI A;  4AYP A;  4Q2B A;  4F10 A;  1KZO B;  1F1S A;  3E80 A;  3ANK A;  2H6I B;  2A8Z A;  1FO3 A;  1H37 A;  3C72 B;  3VSM A;  5IK6 A;  3P5R A;  5MEH A;  1KFG A;  1J0M A;  2FUQ A;  1NI1 B;  3M71 A;  3QFZ A;  2WII B;  2B39 A;  3SDV A;  2E22 A;  2NVP A;  4ZRP A;  1O1R B;  1N4S B;  3A0O A;  2X03 A;  4OK2 A;  3DSX B;  1SA4 B;  4GTT B;  1CEM A;  5GZK A;  3GLY A;  3DSV B;  1S64 B;  3QT3 A;  3RX5 A;  1O5M B;  1H3C A;  2B4F A;  3VXD A;  1LOH A;  3S4D A;  2Z07 A;  3QSP A;  3DRA B;  1JS4 A;  3ACS A;  5JMF A;  1HZF A;  2XWB B;  1FT1 B;  5AGD A;  3SDU A;  5KKB A;  1XWQ A;  3RRS A;  2ZIS B;  5JPN B;  1I8Q A;  1N7R A;  5DGR A;  4D4B A;  5EAT A;  5M7Y A;  1TN6 B;  2CQS A;  3M72 A;  4DOD A;  1TF4 A;  3S4B A;  3DSS B;  3PZ2 B;  1F9D A;  1KS8 A;  1V5D A;  3OED A;  4RNQ A;  1AGM A;  2FUT A;  4LNG B;  2P0V A;  2BRV X;  2JF4 A;  1V7V A;  1H13 A;  1KKT A;  4AYR A;  1S63 B;  3WC3 A;  2PMV A;  5IK0 A;  3M7E A;  3S4C A;  3HXB B;  3M76 A;  4WU0 A;  1K72 A;  1GXM A;  5IM1 A;  2IEJ B;  1FP3 A;  3REN A;  3D3I A;  1N21 A;  1X9D A;  1R76 A;  1WU6 A;  1H54 A;  2BB6 A;  3M7C A;  1W3Y A;  3CU7 A;  3KQ4 A;  2BBC A;  3M77 A;  1FMI A;  5ILK A;  1L1Y A;  2FV0 A;  2WIN B;  3W7X A;  4FXG B;  5FO8 B;  3M75 A;  1O6Q A;  1L2A A; 
#chains in the Genus database with same CATH homology
 1D8E B;  1RQ5 A;  2QNO A;  3D5S A;  1AYX A;  1DOG A;  3S9V A;  1H36 A;  2RI8 A;  3Q78 B;  1H39 A;  3EUV B;  4V1R A;  3W5N A;  4YCR A;  3PZ3 B;  2V8I A;  1NC5 A;  4TXT A;  4GTM B;  1NXC A;  4LIX A;  5DGQ A;  4BOJ A;  3H3K A;  3K11 A;  1KSD A;  1KRE A;  3KSL B;  4KTP A;  3X17 A;  1WU4 A;  2VN4 A;  1UG9 A;  3DST B;  1N94 B;  1KWF A;  4ZRQ A;  3S4A A;  4EHM B;  2V3P A;  2AFA A;  4D4D A;  3Q73 B;  1G6I A;  1O79 A;  3E73 A;  3Q7F B;  3RJ3 A;  2DRS A;  4L0G A;  4ZH1 A;  1GA2 A;  3E32 B;  4ZG8 A;  1N9A B;  4J5T A;  3SDQ A;  4KKJ A;  2BED B;  3WKG A;  4EL8 A;  3QPF A;  1V7X A;  1KRF A;  3SDT A;  1LF9 A;  4YDO B;  1O6R A;  1F9O A;  1H3A A;  1SQC A;  2A73 B;  3ANJ A;  3QDE A;  3QRY A;  2G0D A;  2H6G B;  1JCQ B;  1FAE A;  2WY7 A;  5CZL A;  1QQF A;  3QFY A;  1W6J A;  2ZIR B;  4GTV B;  3WIW A;  3WIQ A;  1DL2 A;  1QBQ B;  2DRQ A;  3D5R A;  2ZZR A;  2SQC A;  3CIH A;  4Z4J A;  4YDE B;  4QT9 A;  3QT9 A;  3WUX A;  3E33 B;  4L9P B;  5M7I A;  1O1S B;  1UT9 A;  1NL4 B;  1QSJ A;  1W6K A;  4D4A A;  2F0Y B;  3SAE A;  3RSY A;  1CLC A;  3DSU B;  3T33 A;  3E6U A;  4D94 A;  1JCS B;  3M74 A;  1DCE B;  1GAH A;  1LD7 B;  2JG0 A;  3RX7 A;  3Q75 B;  2AHG A;  2BB5 A;  4Q88 A;  4GL3 A;  4DOE A;  4ONT A;  5GW7 A;  2H6H B;  2EAC A;  3PYB A;  3ON6 A;  2R2L B;  3AFJ A;  3E37 B;  2AHF A;  4WVC A;  3E30 B;  3ANI A;  2GOX A;  3HXF B;  4KTR A;  4LNB B;  1JCR B;  1GXN A;  5CD2 A;  1KSC A;  4MU9 A;  1FPP B;  3WKI A;  1LTX B;  3PZ1 B;  1D8D B;  4M76 A;  3EQA A;  1TNB B;  4JJJ A;  1XW2 A;  1H14 A;  2F6D A;  1IS9 A;  1H3B A;  2EAD A;  4Z4L A;  3A3V A;  1G9J A;  3H7L A;  3W7T A;  2OKX A;  2NOJ A;  4D4C A;  3Q7A B;  2V8K A;  3M78 A;  2EAE A;  3M7B A;  2D8L A;  3GT5 A;  2RGK A;  5CA3 A;  2JJB A;  4L6X A;  1H35 A;  3SFY B;  2XWJ B;  3EZ8 A;  3SDR A;  1GLM A;  1G87 A;  3M7L A;  3TF4 A;  3KSQ B;  3E34 B;  4TF4 A;  5JPM B;  3OXU A;  2ZBL A;  5GY3 A;  3DSW B;  3GZK A;  3WKH A;  2GZ6 A;  4GTQ B;  3WKF A;  2XFG A;  1TN7 B;  4LNV A;  4GTP B;  1N95 B;  3W7W A;  2G02 A;  4FUS A;  2DRR A;  2EAB A;  2V8J A;  3P5P A;  1O6H A;  4KKI A;  2RI9 A;  1X81 B;  1V7W A;  5E2J A;  1IA7 A;  3EU5 B;  3HXE B;  1FO2 A;  1FT2 B;  3PYA A;  1TNY B;  1WZZ A;  4WVB A;  4GTR B;  2D5J A;  1C3D A;  1G9G A;  1FCE A;  2DRO A;  2YIK A;  1N4Q B;  4AYQ A;  3QXF A;  3HXC B;  2WYN A;  2H6F B;  3SQC A;  1IA6 A;  1KZP B;  3QWT A;  3P2C A;  3HXD B;  4CE7 A;  1TNO B;  3K7X A;  3EU8 A;  4MBG B;  3RX8 A;  1N4P B;  3M73 A;  2FUZ A;  5FO7 B;  2PN5 A;  3QXQ A;  2I07 B;  3KLS A;  1SA5 B;  1GSZ A;  2WY8 A;  1HCU A;  1MZC B;  2V3N A;  5FO9 B;  3W5M A;  3WIR A;  1GHQ A;  4V1S A;  4GTS B;  4CJ1 A;  1H12 A;  1VD5 A;  3PZ4 B;  4WVA A;  3Q79 B;  1GXO A;  3SFX B;  4ZH5 A;  1TNZ B;  1UMP A;  4BOK A;  2XQW A;  1LD8 B;  2FBA A;  4XUV A;  4FXK B;  3DPY B;  1WU5 A;  4C1S A;  3G6J B;  3QG0 A;  2FV1 A;  2CQT A;  3W7U A;  1TNU B;  3H2W A;  4GTO B;  4AYO A;  1TN8 B;  1XWT A;  1ULV A;  1LF6 A;  3ACT A;  2VN7 A;  2GH4 A;  1FBW A;  4CJ0 A;  1V5C A;  3VW5 A;  3W7S A;  1N4R B;  3PMM A;  5FOB B;  1O1T B;  1FBO A;  1GAI A;  4AYP A;  4Q2B A;  1KZO B;  3ANK A;  2H6I B;  2A8Z A;  1FO3 A;  1H37 A;  3C72 B;  3P5R A;  5MEH A;  1KFG A;  1NI1 B;  3M71 A;  3QFZ A;  2WII B;  2B39 A;  3SDV A;  2NVP A;  4ZRP A;  1O1R B;  1N4S B;  3DSX B;  1SA4 B;  4GTT B;  1CEM A;  5GZK A;  3GLY A;  3DSV B;  1S64 B;  3QT3 A;  3RX5 A;  1O5M B;  1H3C A;  2B4F A;  3VXD A;  3S4D A;  2Z07 A;  3QSP A;  3DRA B;  1JS4 A;  3ACS A;  1HZF A;  2XWB B;  1FT1 B;  5AGD A;  3SDU A;  5KKB A;  1XWQ A;  3RRS A;  2ZIS B;  5JPN B;  5DGR A;  4D4B A;  5M7Y A;  1TN6 B;  2CQS A;  3M72 A;  4DOD A;  1TF4 A;  3S4B A;  3DSS B;  3PZ2 B;  1F9D A;  1KS8 A;  1V5D A;  3OED A;  1AGM A;  4LNG B;  2P0V A;  2JF4 A;  1V7V A;  1H13 A;  1KKT A;  4AYR A;  1S63 B;  3WC3 A;  2PMV A;  3S4C A;  3M7E A;  3HXB B;  3M76 A;  4WU0 A;  1GXM A;  1K72 A;  2IEJ B;  1FP3 A;  3REN A;  3D3I A;  1X9D A;  1R76 A;  1WU6 A;  1H54 A;  2BB6 A;  3M7C A;  3CU7 A;  3KQ4 A;  2BBC A;  3M77 A;  1FMI A;  1L1Y A;  2FV0 A;  2WIN B;  3W7X A;  4FXG B;  5FO8 B;  3M75 A;  1O6Q A;  1L2A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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