4E1Y | Genus

Total Genus 139

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	139
sequence length	353
structure length	353
Chain Sequence	GSHPFDQAVVKDPTASYVDVKARRTFLQSGQLDDRLKAALPKEYDCTTEATPNPQQGEMVIPRRYLSGNHGPVNPDYEPVVTLYRDFEKISATLGNLYVATGKPVYATCLLNMLDKWAKADALLNYDPKSQSWYQVEWSAATAAFALSTMMAEPNVDTAQRERVVKWLNRVARHQTSFPGGDTSCCNNASYWRGQEATIIGVISKDDELFRWGLGRYVQAMGLINEDGSFVHEMTRHEQSLHYQNYAMLPLTMIAETASRQGIDLYAYKENGRDIHSARKFVFAAVKNPDLIKKYASEPQDTRAFKPGRGDLNWIEYQRARFGFADELGFMTVPIFDPRTGGSGTLLAYKPQG

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
source organism	Sphingomonas
publication title	Induced-fit motion of a lid loop involved in catalysis in alginate lyase A1-III pubmed doi rcsb
molecule keywords	Alginate lyase
total genus	139
structure length	353
sequence length	353
chains with identical sequence	B
ec nomenclature	ec 4.2.2.3: Mannuronate-specific alginate lyase.
pdb deposition date	2012-03-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF05426	Alginate_lyase	Alginate lyase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.50.10.100	Mainly Alpha	Alpha/alpha barrel	Glycosyltransferase	Chondroitin AC/alginate lyase	4e1yA00

1X1HA 2WCOA 4FNVA 2Q1FA 2FUTA 1QAZA 1F9GA 1HV6A 1OJOA 1RWFA 3NNBA 5JMFA 3E7JA 1OJNA 1RWGA 3AFLA 3NFVA 4F10A 5JMDA 1HMUA 1F1SA 4OZVA 1N7PA 2BRWA 4OJZA 1OJPA 1RWCA 3E80A 2WDAA 2E24A 1I8QA 1HM3A 1RWHA 1EGUA 1W3YA 3VSMA 1CB8A 1LXMA 4MMHA 1N7QA 1RWAA 4F13A 1N7OA 4NEIA 1LXKA 2BRPA 4OZWA 3A0OA 1J0MA 2FUQA 1N7NA 4E1YA 2E22A 1J0NA 1RW9A 1LOHA 4OK2A 4OK4A 4MMIA 2X03A 1HM2A 1C82A 1X1IA 1N7RA 1HMWA 2BRVX 3VSNA 1HN0A 1X1JA 1OJMA
chains in the Genus database with same CATH superfamily

2BB5A 2WIIB 1WU4A 3M7LA 2XFGA 3NFVA 3LZ9A 3S4BA 1HZFA 1GAIA 3QG0A 1TN7B 3E80A 1NL4B 2GZ6A 3SAEA 5IK9A 1F9DA 1LD7B 1XWTA 1KZOB 1N1ZA 3X17A 1UT9A 5ILZA 1N7NA 3M71A 1FMIA 1XWQA 5EAUA 5FOBB 5M7YA 1X1IA 5IK0A 3RX8A 3M74A 1X1HA 1O1RB 1KRFA 3PZ3B 3QSPA 2R2LB 2D8LA 5IL3A 1G6IA 1RWFA 3HXEB 1H37A 1N21A 4L9PB 2XQWA 3GZKA 3QT9A 1HM3A 1JCQB 1FT1B 1LF9A 4OZWA 4V1SA 1R76A 3DSWB 2G02A 1V5CA 5CA3A 1O1TB 4AYRA 5GW7A 1HM2A 3H7LA 3P5RA 3VSNA 4KKJA 5C05A 4V1RA 2FV1A 2A73B 3SDUA 3C72B 2JJBA 1IS9A 1GXOA 1TNBB 3M75A 2ONHA 2FBAA 2GOXA 3RSYA 1W3YA 1O6QA 1TF4A 3RJ3A 1CLCA 2ZBLA 3EU5B 4LNBB 3W7TA 3A0OA 1SA5B 4EL8A 4RNQA 3D3IA 4GTOB 3Q79B 3K11A 3CU7A 4GL3A 1D8DB 2BRVX 2FUZA 1O79A 3RENA 4AYQA 2BB6A 1QQFA 3WUXA 4MU9A 2H6HB 1CEMA 2WYNA 1RWGA 2VN4A 3KSLB 1N7PA 2EABA 2EACA 3QWTA 4YDEB 3S4AA 4AYPA 1AGMA 5IL8A 1KS8A 4D4AA 3P5PA 2A8ZA 3SFYB 3KLSA 3VW5A 3M76A 3GLYA 1J0MA 1JS4A 1C3DA 1O1SB 4OK2A 4D4DA 4Q88A 5CD2A 3D5RA 3ANJA 3OEDA 2PMVA 3E6UA 1FBWA 4BOKA 5JMDA 1ULVA 2BRWA 1H3CA 2D5JA 4FXKB 2WDAA 1UMPA 3M7CA 4C1SA 3VSMA 5IKHA 4JJJA 2V8JA 1DL2A 1H3BA 3E32B 3OXUA 1QBQB 2XWJB 4FJQA 4OK4A 4DOEA 5AGDA 1RQ5A 2I07B 5JPNB 3DRAB 2B4FA 5FO7B 1FBOA 1GXNA 3M7EA 1X81B 3WKGA 1JCRB 4GTQB 1N4RB 2WY7A 3M78A 1KREA 2RI9A 1WZZA 3SDRA 2AFAA 3QFYA 3WKIA 1H39A 4ZRQA 5IM1A 1I8QA 4D4CA 1F9OA 3QFZA 2B39A 1KKTA 1FP3A 3Q78B 1NI1B 2YIKA 1QSJA 4MMIA 3QXQA 4GTMB 4GTPB 1G9GA 1X9DA 3PZ1B 1FT2B 1HX9A 1TN8B 2V3NA 5GY3A 3QXFA 2RI8A 4XUVA 5CZLA 3RX5A 3GT5A 3SDTA 4GTVB 4GTTB 1J0NA 3ACTA 4ZG8A 1FO3A 3W7SA 1OJMA 1W6KA 3DSTB 4FNVA 1W6JA 1TNUB 3A3VA 3AFLA 1N1BA 3Q7FB 3D5SA 3P2CA 4LIXA 2ONGA 5ILJA 4YDOB 1HCUA 1MZCB 2AHFA 3Q75B 1L1YA 4KKIA 5E2JA 4E1YA 2JF4A 3QRYA 1K72A 3W7XA 1FCEA 2DRQA 3DSSB 3HXDB 4YCRA 3W7UA 3PMMA 1UG9A 1TN6B 4Z4LA 1OJOA 3DPYB 4WVBA 1OJNA 4F10A 2NVPA 1HMUA 3EZ8A 5DGRA 1EGUA 3E37B 3KQ4A 3E30B 4TF4A 1N9AB 3DSVB 1N24A 4TXTA 1N22A 2EAEA 1H36A 1V7VA 2V3PA 2ZZRA 4GTRB 5GZKA 3S4DA 1HV6A 3NNBA 5DHKA 3E7JA 1N94B 1F1SA 3DSUB 2DROA 2ZISB 3CIHA 3Q7AB 4ZH5A 3S4CA 1CB8A 1DCEB 1GSZA 2J5CA 1KWFA 2BRPA 3H2WA 1H12A 4ZRPA 1FO2A 1IA6A 5MEHA 3VXDA 1AYXA 1WU5A 4DI5A 1HXGA 1LD8B 4QT9A 1WU6A 1HMWA 4M76A 1XW2A 5DGQA 3M73A 2Q1FA 1N20A 1DOGA 2WY8A 4EHMB 1NXCA 2H6FB 4OZVA 2V8KA 3M72A 3G4DA 2V8IA 3SDQA 2OKXA 4D4BA 1LTXB 3EUVB 2Z07A 1H3AA 3KSQB 4LNGB 2JG0A 1KZPB 2FV0A 3QDEA 3ACSA 3EU8A 3N0GA 4AYOA 1LOHA 2H6IB 3M01A 3PYBA 2H6GB 3WKHA 2BBCA 1HN0A 4FUSA 3G4FA 5ILYA 3M00A 3W7WA 1SQCA 3E34B 4Z4JA 2ZIRB 1OJPA 1FPPB 2P0VA 1GXMA 1RWHA 1GHQA 4MMHA 1N7QA 3ON6A 3TF4A 1KSCA 1VD5A 3M77A 1NC5A 4L6XA 5IK6A 4BOJA 3HXCB 2EADA 3SFXB 1N4QB 1TNOB 1KFGA 2FUTA 3E33B 1GLMA 4CE7A 3N0FA 3RRSA 4CJ1A 5KKBA 4CJ0A 5M7IA 1GAHA 3DSXB 3PZ4B 5FO9B 2E24A 1SA4B 1G87A 1RWAA 1N7OA 1LXKA 1TNZB 1RW9A 4MBGB 1V5DA 3W5MA 1L2AA 1N7RA 2BEDB 2F6DA 1TNYB 3ANIA 2DRRA 1QAZA 1V7WA 4L0GA 2CQTA 2GH4A 3H3KA 4ONTA 3WC3A 1HXCA 1KSDA 1H54A 5EASA 5DHIA 2AHGA 4J5TA 1LXMA 5FO8B 3M7BA 1LF6A 4LNVA 1H14A 4GAXA 1D8EB 4ZH1A 5ILIA 1V7XA 4DODA 3PZ2B 2WCOA 5ILDA 3RX7A 1O5MB 2F0YB 4KTRA 1HXAA 1H35A 1N95B 3EQAA 2DRSA 1O6RA 1N4PB 4WU0A 3SQCA 3WKFA 5IKAA 3AFJA 4KTPA 4Q2BA 1FAEA 3ANKA 1O6HA 2QNOA 1H13A 1IA7A 3T33A 2PN5A 3WIQA 2CQSA 2RGKA 1N4SB 1G9JA 2SQCA 3SDVA 2X03A 1C82A 3PYAA 1S64B 1X1JA 2VN7A 4WVAA 5ILHA 1F9GA 3M02A 3QT3A 5EATA 3K7XA 5JMFA 5JPMB 3HXBB 3WIWA 1S63B 4OJZA 1RWCA 3E73A 1N23A 2XWBB 3W5NA 4GTSB 2G0DA 4D94A 1GA2A 4F13A 2NOJA 4NEIA 4FXGB 2FUQA 2E22A 3S9VA 2IEJB 3HXFB 3QPFA 3Q73B 2WINB 3WIRA 4WVCA 5ILKA 1JCSB 3G6JB
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1X1H A;  2WCO A;  4FNV A;  2Q1F A;  2FUT A;  1QAZ A;  1F9G A;  1HV6 A;  1OJO A;  1RWF A;  3NNB A;  5JMF A;  3E7J A;  1OJN A;  1RWG A;  3AFL A;  3NFV A;  4F10 A;  5JMD A;  1HMU A;  1F1S A;  4OZV A;  1N7P A;  2BRW A;  4OJZ A;  1OJP A;  1RWC A;  3E80 A;  2WDA A;  2E24 A;  1I8Q A;  1HM3 A;  1RWH A;  1EGU A;  1W3Y A;  3VSM A;  1CB8 A;  1LXM A;  4MMH A;  1N7Q A;  1RWA A;  4F13 A;  1N7O A;  4NEI A;  1LXK A;  2BRP A;  4OZW A;  3A0O A;  1J0M A;  2FUQ A;  1N7N A;  4E1Y A;  2E22 A;  1J0N A;  1RW9 A;  1LOH A;  4OK2 A;  4OK4 A;  4MMI A;  2X03 A;  1HM2 A;  1C82 A;  1X1I A;  1N7R A;  1HMW A;  2BRV X;  3VSN A;  1HN0 A;  1X1J A;  1OJM A; 
#chains in the Genus database with same CATH topology
 2BB5 A;  2WII B;  1WU4 A;  3M7L A;  2XFG A;  3NFV A;  3LZ9 A;  3S4B A;  1HZF A;  1GAI A;  3QG0 A;  1TN7 B;  3E80 A;  1NL4 B;  2GZ6 A;  3SAE A;  5IK9 A;  1F9D A;  1LD7 B;  1XWT A;  1KZO B;  1N1Z A;  3X17 A;  1UT9 A;  5ILZ A;  1N7N A;  3M71 A;  1FMI A;  1XWQ A;  5EAU A;  5FOB B;  5M7Y A;  1X1I A;  5IK0 A;  3RX8 A;  3M74 A;  1X1H A;  1O1R B;  1KRF A;  3PZ3 B;  3QSP A;  2R2L B;  2D8L A;  5IL3 A;  1G6I A;  1RWF A;  3HXE B;  1H37 A;  1N21 A;  4L9P B;  2XQW A;  3GZK A;  3QT9 A;  1HM3 A;  1JCQ B;  1FT1 B;  1LF9 A;  4OZW A;  4V1S A;  1R76 A;  3DSW B;  2G02 A;  1V5C A;  5CA3 A;  1O1T B;  4AYR A;  5GW7 A;  1HM2 A;  3H7L A;  3P5R A;  3VSN A;  4KKJ A;  5C05 A;  4V1R A;  2FV1 A;  2A73 B;  3SDU A;  3C72 B;  2JJB A;  1IS9 A;  1GXO A;  1TNB B;  3M75 A;  2ONH A;  2FBA A;  2GOX A;  3RSY A;  1W3Y A;  1O6Q A;  1TF4 A;  3RJ3 A;  1CLC A;  2ZBL A;  3EU5 B;  4LNB B;  3W7T A;  3A0O A;  1SA5 B;  4EL8 A;  4RNQ A;  3D3I A;  4GTO B;  3Q79 B;  3K11 A;  3CU7 A;  4GL3 A;  1D8D B;  2BRV X;  2FUZ A;  1O79 A;  3REN A;  4AYQ A;  2BB6 A;  1QQF A;  3WUX A;  4MU9 A;  2H6H B;  1CEM A;  2WYN A;  1RWG A;  2VN4 A;  3KSL B;  1N7P A;  2EAB A;  2EAC A;  3QWT A;  4YDE B;  3S4A A;  4AYP A;  1AGM A;  5IL8 A;  1KS8 A;  4D4A A;  3P5P A;  2A8Z A;  3SFY B;  3KLS A;  3VW5 A;  3M76 A;  3GLY A;  1J0M A;  1JS4 A;  1C3D A;  1O1S B;  4OK2 A;  4D4D A;  4Q88 A;  5CD2 A;  3D5R A;  3ANJ A;  3OED A;  2PMV A;  3E6U A;  1FBW A;  4BOK A;  5JMD A;  1ULV A;  2BRW A;  1H3C A;  2D5J A;  4FXK B;  2WDA A;  1UMP A;  3M7C A;  4C1S A;  3VSM A;  5IKH A;  4JJJ A;  2V8J A;  1DL2 A;  1H3B A;  3E32 B;  3OXU A;  1QBQ B;  2XWJ B;  4FJQ A;  4OK4 A;  4DOE A;  5AGD A;  1RQ5 A;  2I07 B;  5JPN B;  3DRA B;  2B4F A;  5FO7 B;  1FBO A;  1GXN A;  3M7E A;  1X81 B;  3WKG A;  1JCR B;  4GTQ B;  1N4R B;  2WY7 A;  3M78 A;  1KRE A;  2RI9 A;  1WZZ A;  3SDR A;  2AFA A;  3QFY A;  3WKI A;  1H39 A;  4ZRQ A;  5IM1 A;  1I8Q A;  4D4C A;  1F9O A;  3QFZ A;  2B39 A;  1KKT A;  1FP3 A;  3Q78 B;  1NI1 B;  2YIK A;  1QSJ A;  4MMI A;  3QXQ A;  4GTM B;  4GTP B;  1G9G A;  1X9D A;  3PZ1 B;  1FT2 B;  1HX9 A;  1TN8 B;  2V3N A;  5GY3 A;  3QXF A;  2RI8 A;  4XUV A;  5CZL A;  3RX5 A;  3GT5 A;  3SDT A;  4GTV B;  4GTT B;  1J0N A;  3ACT A;  4ZG8 A;  1FO3 A;  3W7S A;  1OJM A;  1W6K A;  3DST B;  4FNV A;  1W6J A;  1TNU B;  3A3V A;  3AFL A;  1N1B A;  3Q7F B;  3D5S A;  3P2C A;  4LIX A;  2ONG A;  5ILJ A;  4YDO B;  1HCU A;  1MZC B;  2AHF A;  3Q75 B;  1L1Y A;  4KKI A;  5E2J A;  4E1Y A;  2JF4 A;  3QRY A;  1K72 A;  3W7X A;  1FCE A;  2DRQ A;  3DSS B;  3HXD B;  4YCR A;  3W7U A;  3PMM A;  1UG9 A;  1TN6 B;  4Z4L A;  1OJO A;  3DPY B;  4WVB A;  1OJN A;  4F10 A;  2NVP A;  1HMU A;  3EZ8 A;  5DGR A;  1EGU A;  3E37 B;  3KQ4 A;  3E30 B;  4TF4 A;  1N9A B;  3DSV B;  1N24 A;  4TXT A;  1N22 A;  2EAE A;  1H36 A;  1V7V A;  2V3P A;  2ZZR A;  4GTR B;  5GZK A;  3S4D A;  1HV6 A;  3NNB A;  5DHK A;  3E7J A;  1N94 B;  1F1S A;  3DSU B;  2DRO A;  2ZIS B;  3CIH A;  3Q7A B;  4ZH5 A;  3S4C A;  1CB8 A;  1DCE B;  1GSZ A;  2J5C A;  1KWF A;  2BRP A;  3H2W A;  1H12 A;  4ZRP A;  1FO2 A;  1IA6 A;  5MEH A;  3VXD A;  1AYX A;  1WU5 A;  4DI5 A;  1HXG A;  1LD8 B;  4QT9 A;  1WU6 A;  1HMW A;  4M76 A;  1XW2 A;  5DGQ A;  3M73 A;  2Q1F A;  1N20 A;  1DOG A;  2WY8 A;  4EHM B;  1NXC A;  2H6F B;  4OZV A;  2V8K A;  3M72 A;  3G4D A;  2V8I A;  3SDQ A;  2OKX A;  4D4B A;  1LTX B;  3EUV B;  2Z07 A;  1H3A A;  3KSQ B;  4LNG B;  2JG0 A;  1KZP B;  2FV0 A;  3QDE A;  3ACS A;  3EU8 A;  3N0G A;  4AYO A;  1LOH A;  2H6I B;  3M01 A;  3PYB A;  2H6G B;  3WKH A;  2BBC A;  1HN0 A;  4FUS A;  3G4F A;  5ILY A;  3M00 A;  3W7W A;  1SQC A;  3E34 B;  4Z4J A;  2ZIR B;  1OJP A;  1FPP B;  2P0V A;  1GXM A;  1RWH A;  1GHQ A;  4MMH A;  1N7Q A;  3ON6 A;  3TF4 A;  1KSC A;  1VD5 A;  3M77 A;  1NC5 A;  4L6X A;  5IK6 A;  4BOJ A;  3HXC B;  2EAD A;  3SFX B;  1N4Q B;  1TNO B;  1KFG A;  2FUT A;  3E33 B;  1GLM A;  4CE7 A;  3N0F A;  3RRS A;  4CJ1 A;  5KKB A;  4CJ0 A;  5M7I A;  1GAH A;  3DSX B;  3PZ4 B;  5FO9 B;  2E24 A;  1SA4 B;  1G87 A;  1RWA A;  1N7O A;  1LXK A;  1TNZ B;  1RW9 A;  4MBG B;  1V5D A;  3W5M A;  1L2A A;  1N7R A;  2BED B;  2F6D A;  1TNY B;  3ANI A;  2DRR A;  1QAZ A;  1V7W A;  4L0G A;  2CQT A;  2GH4 A;  3H3K A;  4ONT A;  3WC3 A;  1HXC A;  1KSD A;  1H54 A;  5EAS A;  5DHI A;  2AHG A;  4J5T A;  1LXM A;  5FO8 B;  3M7B A;  1LF6 A;  4LNV A;  1H14 A;  4GAX A;  1D8E B;  4ZH1 A;  5ILI A;  1V7X A;  4DOD A;  3PZ2 B;  2WCO A;  5ILD A;  3RX7 A;  1O5M B;  2F0Y B;  4KTR A;  1HXA A;  1H35 A;  1N95 B;  3EQA A;  2DRS A;  1O6R A;  1N4P B;  4WU0 A;  3SQC A;  3WKF A;  5IKA A;  3AFJ A;  4KTP A;  4Q2B A;  1FAE A;  3ANK A;  1O6H A;  2QNO A;  1H13 A;  1IA7 A;  3T33 A;  2PN5 A;  3WIQ A;  2CQS A;  2RGK A;  1N4S B;  1G9J A;  2SQC A;  3SDV A;  2X03 A;  1C82 A;  3PYA A;  1S64 B;  1X1J A;  2VN7 A;  4WVA A;  5ILH A;  1F9G A;  3M02 A;  3QT3 A;  5EAT A;  3K7X A;  5JMF A;  5JPM B;  3HXB B;  3WIW A;  1S63 B;  4OJZ A;  1RWC A;  3E73 A;  1N23 A;  2XWB B;  3W5N A;  4GTS B;  2G0D A;  4D94 A;  1GA2 A;  4F13 A;  2NOJ A;  4NEI A;  4FXG B;  2FUQ A;  2E22 A;  3S9V A;  2IEJ B;  3HXF B;  3QPF A;  3Q73 B;  2WIN B;  3WIR A;  4WVC A;  5ILK A;  1JCS B;  3G6J B; 
#chains in the Genus database with same CATH homology
 1X1H A;  2WCO A;  4FNV A;  2Q1F A;  2FUT A;  1QAZ A;  1F9G A;  1HV6 A;  1OJO A;  1RWF A;  3NNB A;  5JMF A;  3E7J A;  1OJN A;  1RWG A;  3AFL A;  3NFV A;  4F10 A;  5JMD A;  1HMU A;  1F1S A;  4OZV A;  1N7P A;  2BRW A;  4OJZ A;  1OJP A;  1RWC A;  3E80 A;  2WDA A;  2E24 A;  1I8Q A;  1HM3 A;  1RWH A;  1EGU A;  1W3Y A;  3VSM A;  1CB8 A;  1LXM A;  4MMH A;  1N7Q A;  1RWA A;  4F13 A;  1N7O A;  4NEI A;  1LXK A;  2BRP A;  4OZW A;  3A0O A;  1J0M A;  2FUQ A;  1N7N A;  4E1Y A;  2E22 A;  1J0N A;  1RW9 A;  1LOH A;  4OK2 A;  4OK4 A;  4MMI A;  2X03 A;  1HM2 A;  1C82 A;  1X1I A;  1N7R A;  1HMW A;  2BRV X;  3VSN A;  1HN0 A;  1X1J A;  1OJM A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4E1YA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations