5KNNA

Evolutionary gain of alanine mischarging to non-cognate trnas with a g4:u69 base pair
Total Genus 154
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
sequence length
450
structure length
450
Chain Sequence
TLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Alanine--tRNA ligase, cytoplasmic
total genus 154
structure length 450
sequence length 450
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 6.1.1.7: Alanine--tRNA ligase.
pdb deposition date 2016-06-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.930.10 Alpha Beta 2-Layer Sandwich BirA Bifunctional Protein; domain 2 Bira Bifunctional Protein; Domain 2 5knnA01
2EAYA 2RHQB 3EFSA 1EFWA 1C0AA 2Q7HA 4RQFA 3M4PA 2ALYA 2I4LA 5C51B 4WJ3M 4YRIA 2RHSA 4L87A 2Q7EA 2DZ9A 3G1ZA 4P3NA 3BJUA 1EOVA 3QO5A 4YRQA 4EO4A 2DKGA 4DPGA 2ODRD 4E51A 4YRJA 4XEMA 1IL2A 3V7SA 4YCWA 2CJ9A 3HRKA 4K88A 3VQYA 4ZIBA 2DTHA 4H2VA 3RACA 1EIYB 3L4GB 4XU0A 1EVKA 4YRNA 2ZR3A 3VQXA 2E1HA 3EFRA 4OP0A 1HXDA 2ALYB 1SETA 2RHSB 1E22A 4P73A 4YROA 3VQWA 4CH5A 1X2GA 1SESA 4LNSA 12ASA 2AMCA 4UPAA 4P72A 4YRMA 1B70A 3I7FA 3WQZA 3UGQA 3UH0A 5K1XA 2EJ9A 2J3MA 3ICAA 3IKMB 4TVAA 4H2SA 2ZXFA 4YREA 4YRSA 3NELA 4BWAA 11ASA 3L1AA 4XTYA 2QHSA 1W66A 4YRTA 4RMFA 4TQDA 1BBWA 4PG3A 3LSSA 4WJ4A 3MEYA 1NJ8A 4XU1A 3CMQA 4XU2A 3REUA 3RKWA 2PMEA 2AMCB 2I4NA 3HFZA 1WLEA 2CGHA 5F5WA 3VQVA 3V7CA 1HC7A 3A74A 1X56A 4TVAB 2QHTA 1PYSB 4X5OA 3A5ZA 1L0WA 3TEHA 2ZR2A 1NNHA 1VQZA 2ARTA 4YRPA 4DQ2A 2EJFA 4HWTA 1X54A 1ASYA 4YRGA 3DSQA 4YRRA 3QO7A 2ZT7A 1EVLA 3RUXA 4P73C 1J5WA 2DEQA 5ELNA 2DTOA 4P3PA 4H2WA 1KMNA 2EL9A 2DU7A 2Q5IA 4YP0A 3VBBA 1WQWA 4YCVA 4K87A 3RL6A 1BBUA 3IKLA 4CH4A 2ZZEA 1NJ2A 3A7UA 3PZCA 4TTVA 4P71A 1X01A 2DXTA 1E1OA 3V8JA 2ZT8A 1WYDA 2ZGWA 1NJ1A 2ARUA 4TQFA 4H2YA 3TUPA 1G5IA 2DQ3A 2FYKA 2Q7GA 3MF1A 4P75A 2I4MA 2E64A 2C7IA 1WQ7A 4H2UA 3RGLA 4KR2A 3HXUA 4HWOA 1YFSA 5KNNA 1Z7NA 3HXVA 4TVWA 3V8KA 4G85A 5HGQA 2QHVA 3HXZA 4UP9A 2E10A 1JJCA 2EJGA 3KFUA 1WNLA 2G4CA 3RKYA 1H4TA 3QNEA 4J15A 1YGBA 2ZZFA 3RKXA 3UGTA 2J3LA 3NETA 4YRKA 3ERRA 4WI1A 2CJBA 4BW9A 5C52B 3A31A 1GGMA 3RF1A 4P71C 1E24A 3IALA 4UP8A 1B70B 1QE0A 2CJAA 4CH3A 4ZTUB 4OLFA 1H4SA 1X2HA 2XGTA 4EX5A 4P75C 4CH6A 2DXUA 4XTUA 4XEOA 3A7RA 1E1TA 5K1PA 3W3SA 1USYA 2E41A 4NCXA 3E9HA 2CIMA 2XTIA 1NJ6A 4HVCA 3BFMA 2ZNJA 1WU7A 3REXA 4P72C 1KMMA 3LC0A 4HWRA 4YRLA 2ZTGA 2ZNIA 4H2XB 1EIYA 4XTVA 2ZT5A 2P5IA 3P8TA 3HFZB 2P0LA 4P74A 2C8MA 4UP7A 4XTWA 3V8LA 4CS4A 2E5AA 1B8AA 3HRIA 1SERA 3HXWA 4H2TA 1H4VB 3TEHB 1B76A 3LSQA 1EQRA 3OD1A 3PCOA 2DZCA 2ODRC 2ZT6A 1X55A 1YB3A 2ZINA 4RDXA 1RIQA 2ZCEA 1ASZA 3MF2A 1BIBA 4WF2A 1NYRA 2QHUA 2DVEA 1QF6A 3A7AA 1HTTA 2IY5A 3HTZA 4ZTZB 1G51A 2PMFA 4G84A 1BIAA 5C53B 1H4QA 2E65A 1ADYA 4KQEA 1LYLA 2ARSA 2AKWA 4YDQA 3NEMA 3PCOB 4CS2A 1WPYA 4PHCA 1SRYA 5ELOA 4CS3A 4O2DA 1USYC 1ADJA 2E3CA 4YRCA 1YFRA 3V7RA 3QTCA 2ZZGA 1G5HA 3P8YA 3UFGA 2HNIA 2Q5HA 3FJPA 1PYSA 3HXYA 4YPFA 1KOGA 3P8VA 4K86A 1B7YA 3A5YA 4P74C 3HXXA 3L2ZA 5E3IA 2IY5B 3E9IA 2DTIA 2DQ0A 3NENA 3HY0A 4H2XA 2DU5A 4AH6A 2RHQA 2ZIMA 2ZIOA 2I4OA 3RIRA 1YFTA 1ATIA 2AKWB 1JJCB 4H02A 3A32A 2EWNA 3HY1A 4KR3A 3M4QA 4XTZA 3HFVA 3QO8A 1N9WA 4P3OA 3TEGA 4Q15A 4TWAA 4XTXA 2DJZA 4HA8A 1FYFA 4Q6GA 1NYQA 4YCUA 4RQEA 1B7YB 1Z7MA 3R07A 4HWPA 1NJ5A 4TVYA 3IG2A 4XU3A 4YRFA 2DDZA 3L4GA 4YYEA 4HWSA
chains in the Genus database with same CATH superfamily
2EAYA 2RHQB 3EFSA 1EFWA 1C0AA 2Q7HA 4RQFA 3M4PA 2ALYA 2I4LA 5C51B 4WJ3M 4YRIA 2RHSA 4L87A 2Q7EA 2DZ9A 3G1ZA 4P3NA 3BJUA 1EOVA 3QO5A 4YRQA 4EO4A 2DKGA 4DPGA 2ODRD 4E51A 4YRJA 4XEMA 1IL2A 3V7SA 4YCWA 2CJ9A 3HRKA 4K88A 3VQYA 4ZIBA 2DTHA 4H2VA 3RACA 1EIYB 3L4GB 4HT4A 4XU0A 1EVKA 4YRNA 2ZR3A 3VQXA 2E1HA 3EFRA 4OP0A 1HXDA 2ALYB 1SETA 2RHSB 1E22A 4P73A 4YROA 3VQWA 4CH5A 1X2GA 1SESA 4LNSA 12ASA 2AMCA 4UPAA 4P72A 4YRMA 1B70A 3I7FA 3WQZA 3UGQA 3UH0A 5K1XA 2EJ9A 2J3MA 3ICAA 3IKMB 4TVAA 4H2SA 2ZXFA 4YREA 4YRSA 3NELA 4BWAA 11ASA 3L1AA 4XTYA 2QHSA 1W66A 4YRTA 4RMFA 4TQDA 1BBWA 4PG3A 3LSSA 4WJ4A 3MEYA 1NJ8A 4XU1A 3CMQA 4XU2A 3REUA 3RKWA 2PMEA 2AMCB 2I4NA 3HFZA 1WLEA 2CGHA 5F5WA 3VQVA 3V7CA 1HC7A 3A74A 1X56A 4TVAB 2QHTA 1PYSB 4X5OA 3A5ZA 1L0WA 3TEHA 2ZR2A 1NNHA 1VQZA 2ARTA 4YRPA 4DQ2A 2EJFA 4HWTA 1X54A 1ASYA 4YRGA 3DSQA 4YRRA 3QO7A 2ZT7A 1EVLA 3RUXA 4P73C 1J5WA 2DEQA 5ELNA 2DTOA 4P3PA 4H2WA 1KMNA 2EL9A 2DU7A 2Q5IA 4YP0A 3VBBA 1WQWA 4YCVA 4K87A 3RL6A 1BBUA 3IKLA 4CH4A 2ZZEA 1NJ2A 3A7UA 3PZCA 4TTVA 4P71A 1X01A 2DXTA 1E1OA 3V8JA 2ZT8A 1WYDA 2ZGWA 1NJ1A 2ARUA 4TQFA 4H2YA 3TUPA 1G5IA 2DQ3A 2FYKA 2Q7GA 3MF1A 4P75A 2I4MA 2E64A 2C7IA 1WQ7A 4H2UA 3RGLA 4KR2A 3HXUA 4LVIA 4HWOA 1YFSA 5KNNA 1Z7NA 3HXVA 4TVWA 3V8KA 4G85A 5HGQA 2QHVA 3HXZA 4UP9A 2E10A 4LVMA 1JJCA 2EJGA 3KFUA 1WNLA 2G4CA 3RKYA 1H4TA 3QNEA 4J15A 1YGBA 2ZZFA 3RKXA 3UGTA 2J3LA 3NETA 4YRKA 3ERRA 4WI1A 2CJBA 4BW9A 5C52B 3A31A 1GGMA 3RF1A 4P71C 1E24A 3IALA 4UP8A 1B70B 1QE0A 2CJAA 4CH3A 4ZTUB 4OLFA 1H4SA 1X2HA 2XGTA 4EX5A 4P75C 4CH6A 2DXUA 4XTUA 4XEOA 3A7RA 1E1TA 5K1PA 3W3SA 1USYA 2E41A 4NCXA 3E9HA 2CIMA 2XTIA 1NJ6A 4HVCA 3BFMA 2ZNJA 1WU7A 3REXA 4P72C 1KMMA 3LC0A 4HWRA 4YRLA 2ZTGA 2ZNIA 4H2XB 1EIYA 4XTVA 2ZT5A 2P5IA 3P8TA 3HFZB 2P0LA 4P74A 2C8MA 4UP7A 4XTWA 3V8LA 4CS4A 2E5AA 1B8AA 3HRIA 1SERA 3HXWA 4H2TA 1H4VB 3TEHB 1B76A 3LSQA 1EQRA 3OD1A 3PCOA 2DZCA 2ODRC 2ZT6A 1X55A 1YB3A 2NS6A 2ZINA 4RDXA 1RIQA 2ZCEA 1ASZA 3MF2A 1BIBA 4WF2A 1NYRA 2QHUA 2DVEA 1QF6A 3A7AA 1HTTA 2IY5A 3HTZA 4ZTZB 1G51A 2PMFA 4G84A 1BIAA 3MQZA 5C53B 1H4QA 2A8EA 2E65A 1ADYA 4KQEA 1LYLA 2ARSA 2AKWA 4YDQA 3NEMA 3PCOB 4CS2A 1WPYA 4PHCA 1SRYA 5ELOA 4CS3A 4O2DA 1USYC 1ADJA 2E3CA 4YRCA 1YFRA 3V7RA 3QTCA 2ZZGA 1G5HA 3P8YA 3UFGA 2HNIA 2Q5HA 3FJPA 4LVLA 1PYSA 3HXYA 4YPFA 1KOGA 3P8VA 4K86A 1B7YA 3A5YA 4P74C 3HXXA 3L2ZA 5E3IA 2IY5B 3E9IA 2DTIA 2DQ0A 3NENA 3HY0A 4H2XA 2DU5A 4LVKA 4AH6A 2RHQA 2ZIMA 2ZIOA 2I4OA 3RIRA 1YFTA 1ATIA 2AKWB 1JJCB 4H02A 3A32A 2EWNA 3HY1A 4KR3A 3M4QA 4XTZA 3HFVA 3QO8A 1N9WA 4P3OA 3TEGA 4Q15A 4TWAA 4XTXA 4LVJA 2DJZA 4HA8A 1FYFA 4Q6GA 1NYQA 4YCUA 4RQEA 1B7YB 1Z7MA 3R07A 4HWPA 1NJ5A 4TVYA 3IG2A 4XU3A 4YRFA 2DDZA 3L4GA 4YYEA 4HWSA
chains in the Genus database with same CATH topology
2EAYA 2RHQB 3EFSA 1EFWA 1C0AA 2Q7HA 4RQFA 3M4PA 2ALYA 2I4LA 5C51B 4WJ3M 4YRIA 2RHSA 4L87A 2Q7EA 2DZ9A 3G1ZA 4P3NA 3BJUA 1EOVA 3QO5A 4YRQA 4EO4A 2DKGA 4DPGA 2ODRD 4E51A 4YRJA 4XEMA 1IL2A 3V7SA 4YCWA 2CJ9A 3HRKA 4K88A 3VQYA 4ZIBA 2DTHA 4H2VA 3RACA 1EIYB 3L4GB 4HT4A 4XU0A 1EVKA 4YRNA 2ZR3A 3VQXA 2E1HA 3EFRA 4OP0A 1HXDA 2ALYB 1SETA 2RHSB 1E22A 4P73A 4YROA 3VQWA 4CH5A 1X2GA 1SESA 4LNSA 12ASA 2AMCA 4UPAA 4P72A 4YRMA 1B70A 3I7FA 3WQZA 3UGQA 3UH0A 5K1XA 2EJ9A 2J3MA 3ICAA 3IKMB 4TVAA 4H2SA 2ZXFA 4YREA 4YRSA 3NELA 4BWAA 11ASA 3L1AA 4XTYA 2QHSA 1W66A 4YRTA 4RMFA 4TQDA 1BBWA 4PG3A 3LSSA 4WJ4A 3MEYA 1NJ8A 4XU1A 3CMQA 4XU2A 3REUA 3RKWA 2PMEA 2AMCB 2I4NA 3HFZA 1WLEA 2CGHA 5F5WA 3VQVA 3V7CA 1HC7A 3A74A 1X56A 4TVAB 2QHTA 1PYSB 4X5OA 3A5ZA 1L0WA 3TEHA 2ZR2A 1NNHA 1VQZA 2ARTA 4YRPA 4DQ2A 2EJFA 4HWTA 1X54A 1ASYA 4YRGA 3DSQA 4YRRA 3QO7A 2ZT7A 1EVLA 3RUXA 4P73C 1J5WA 2DEQA 5ELNA 2DTOA 4P3PA 4H2WA 1KMNA 2EL9A 2DU7A 2Q5IA 4YP0A 3VBBA 1WQWA 4YCVA 4K87A 3RL6A 1BBUA 3IKLA 4CH4A 2ZZEA 1NJ2A 3A7UA 3PZCA 4TTVA 4P71A 1X01A 2DXTA 1E1OA 3V8JA 2ZT8A 1WYDA 2ZGWA 1NJ1A 2ARUA 4TQFA 4H2YA 3TUPA 1G5IA 2DQ3A 2FYKA 2Q7GA 3MF1A 4P75A 2I4MA 2E64A 2C7IA 1WQ7A 4H2UA 3RGLA 4KR2A 3HXUA 4LVIA 4HWOA 1YFSA 5KNNA 1Z7NA 3HXVA 4TVWA 3V8KA 4G85A 5HGQA 2QHVA 3HXZA 4UP9A 2E10A 4LVMA 1JJCA 2EJGA 3KFUA 1WNLA 2G4CA 3RKYA 1H4TA 3QNEA 4J15A 1YGBA 2ZZFA 3RKXA 3UGTA 2J3LA 3NETA 4YRKA 3ERRA 4WI1A 2CJBA 4BW9A 5C52B 3A31A 1GGMA 3RF1A 4P71C 1E24A 3IALA 4UP8A 1B70B 1QE0A 2CJAA 4CH3A 4ZTUB 4OLFA 1H4SA 1X2HA 2XGTA 4EX5A 4P75C 4CH6A 2DXUA 4XTUA 4XEOA 3A7RA 1E1TA 5K1PA 3W3SA 1USYA 2E41A 4NCXA 3E9HA 2CIMA 2XTIA 1NJ6A 4HVCA 3BFMA 2ZNJA 1WU7A 3REXA 4P72C 1KMMA 3LC0A 4HWRA 4YRLA 2ZTGA 2ZNIA 4H2XB 1EIYA 4XTVA 2ZT5A 2P5IA 3P8TA 3HFZB 2P0LA 4P74A 2C8MA 4UP7A 4XTWA 3V8LA 4CS4A 2E5AA 1B8AA 3HRIA 1SERA 3HXWA 4H2TA 1H4VB 3TEHB 1B76A 3LSQA 1EQRA 3OD1A 3PCOA 2DZCA 2ODRC 2ZT6A 1X55A 1YB3A 2NS6A 2ZINA 4RDXA 1RIQA 2ZCEA 1ASZA 3MF2A 1BIBA 4WF2A 1NYRA 2QHUA 2DVEA 1QF6A 3A7AA 1HTTA 2IY5A 3HTZA 4ZTZB 1G51A 2PMFA 4G84A 1BIAA 3MQZA 5C53B 1H4QA 2A8EA 2E65A 1ADYA 4KQEA 1LYLA 2ARSA 2AKWA 4YDQA 3NEMA 3PCOB 4CS2A 1WPYA 4PHCA 1SRYA 5ELOA 4CS3A 4O2DA 1USYC 1ADJA 2E3CA 4YRCA 1YFRA 3V7RA 3QTCA 2ZZGA 1G5HA 3P8YA 3UFGA 2HNIA 2Q5HA 3FJPA 4LVLA 1PYSA 3HXYA 4YPFA 1KOGA 3P8VA 4K86A 1B7YA 3A5YA 4P74C 3HXXA 3L2ZA 5E3IA 2IY5B 3E9IA 2DTIA 2DQ0A 3NENA 3HY0A 4H2XA 2DU5A 4LVKA 4AH6A 2RHQA 2ZIMA 2ZIOA 2I4OA 3RIRA 1YFTA 1ATIA 2AKWB 1JJCB 4H02A 3A32A 2EWNA 3HY1A 4KR3A 3M4QA 4XTZA 3HFVA 3QO8A 1N9WA 4P3OA 3TEGA 4Q15A 4TWAA 4XTXA 4LVJA 2DJZA 4HA8A 1FYFA 4Q6GA 1NYQA 4YCUA 4RQEA 1B7YB 1Z7MA 3R07A 4HWPA 1NJ5A 4TVYA 3IG2A 4XU3A 4YRFA 2DDZA 3L4GA 4YYEA 4HWSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EAY A;  2RHQ B;  3EFS A;  1EFW A;  1C0A A;  2Q7H A;  4RQF A;  3M4P A;  2ALY A;  2I4L A;  5C51 B;  4WJ3 M;  4YRI A;  2RHS A;  4L87 A;  2Q7E A;  2DZ9 A;  3G1Z A;  4P3N A;  3BJU A;  1EOV A;  3QO5 A;  4YRQ A;  4EO4 A;  2DKG A;  4DPG A;  2ODR D;  4E51 A;  4YRJ A;  4XEM A;  1IL2 A;  3V7S A;  4YCW A;  2CJ9 A;  3HRK A;  4K88 A;  3VQY A;  4ZIB A;  2DTH A;  4H2V A;  3RAC A;  1EIY B;  3L4G B;  4XU0 A;  1EVK A;  4YRN A;  2ZR3 A;  3VQX A;  2E1H A;  3EFR A;  4OP0 A;  1HXD A;  2ALY B;  1SET A;  2RHS B;  1E22 A;  4P73 A;  4YRO A;  3VQW A;  4CH5 A;  1X2G A;  1SES A;  4LNS A;  12AS A;  2AMC A;  4UPA A;  4P72 A;  4YRM A;  1B70 A;  3I7F A;  3WQZ A;  3UGQ A;  3UH0 A;  5K1X A;  2EJ9 A;  2J3M A;  3ICA A;  3IKM B;  4TVA A;  4H2S A;  2ZXF A;  4YRE A;  4YRS A;  3NEL A;  4BWA A;  11AS A;  3L1A A;  4XTY A;  2QHS A;  1W66 A;  4YRT A;  4RMF A;  4TQD A;  1BBW A;  4PG3 A;  3LSS A;  4WJ4 A;  3MEY A;  1NJ8 A;  4XU1 A;  3CMQ A;  4XU2 A;  3REU A;  3RKW A;  2PME A;  2AMC B;  2I4N A;  3HFZ A;  1WLE A;  2CGH A;  5F5W A;  3VQV A;  3V7C A;  1HC7 A;  3A74 A;  1X56 A;  4TVA B;  2QHT A;  1PYS B;  4X5O A;  3A5Z A;  1L0W A;  3TEH A;  2ZR2 A;  1NNH A;  1VQZ A;  2ART A;  4YRP A;  4DQ2 A;  2EJF A;  4HWT A;  1X54 A;  1ASY A;  4YRG A;  3DSQ A;  4YRR A;  3QO7 A;  2ZT7 A;  1EVL A;  3RUX A;  4P73 C;  1J5W A;  2DEQ A;  5ELN A;  2DTO A;  4P3P A;  4H2W A;  1KMN A;  2EL9 A;  2DU7 A;  2Q5I A;  4YP0 A;  3VBB A;  1WQW A;  4YCV A;  4K87 A;  3RL6 A;  1BBU A;  3IKL A;  4CH4 A;  2ZZE A;  1NJ2 A;  3A7U A;  3PZC A;  4TTV A;  4P71 A;  1X01 A;  2DXT A;  1E1O A;  3V8J A;  2ZT8 A;  1WYD A;  2ZGW A;  1NJ1 A;  2ARU A;  4TQF A;  4H2Y A;  3TUP A;  1G5I A;  2DQ3 A;  2FYK A;  2Q7G A;  3MF1 A;  4P75 A;  2I4M A;  2E64 A;  2C7I A;  1WQ7 A;  4H2U A;  3RGL A;  4KR2 A;  3HXU A;  4HWO A;  1YFS A;  5KNN A;  1Z7N A;  3HXV A;  4TVW A;  3V8K A;  4G85 A;  5HGQ A;  2QHV A;  3HXZ A;  4UP9 A;  2E10 A;  1JJC A;  2EJG A;  3KFU A;  1WNL A;  2G4C A;  3RKY A;  1H4T A;  3QNE A;  4J15 A;  1YGB A;  2ZZF A;  3RKX A;  3UGT A;  2J3L A;  3NET A;  4YRK A;  3ERR A;  4WI1 A;  2CJB A;  4BW9 A;  5C52 B;  3A31 A;  1GGM A;  3RF1 A;  4P71 C;  1E24 A;  3IAL A;  4UP8 A;  1B70 B;  1QE0 A;  2CJA A;  4CH3 A;  4ZTU B;  4OLF A;  1H4S A;  1X2H A;  2XGT A;  4EX5 A;  4P75 C;  4CH6 A;  2DXU A;  4XTU A;  4XEO A;  3A7R A;  1E1T A;  5K1P A;  3W3S A;  1USY A;  2E41 A;  4NCX A;  3E9H A;  2CIM A;  2XTI A;  1NJ6 A;  4HVC A;  3BFM A;  2ZNJ A;  1WU7 A;  3REX A;  4P72 C;  1KMM A;  3LC0 A;  4HWR A;  4YRL A;  2ZTG A;  2ZNI A;  4H2X B;  1EIY A;  4XTV A;  2ZT5 A;  2P5I A;  3P8T A;  3HFZ B;  2P0L A;  4P74 A;  2C8M A;  4UP7 A;  4XTW A;  3V8L A;  4CS4 A;  2E5A A;  1B8A A;  3HRI A;  1SER A;  3HXW A;  4H2T A;  1H4V B;  3TEH B;  1B76 A;  3LSQ A;  1EQR A;  3OD1 A;  3PCO A;  2DZC A;  2ODR C;  2ZT6 A;  1X55 A;  1YB3 A;  2ZIN A;  4RDX A;  1RIQ A;  2ZCE A;  1ASZ A;  3MF2 A;  1BIB A;  4WF2 A;  1NYR A;  2QHU A;  2DVE A;  1QF6 A;  3A7A A;  1HTT A;  2IY5 A;  3HTZ A;  4ZTZ B;  1G51 A;  2PMF A;  4G84 A;  1BIA A;  5C53 B;  1H4Q A;  2E65 A;  1ADY A;  4KQE A;  1LYL A;  2ARS A;  2AKW A;  4YDQ A;  3NEM A;  3PCO B;  4CS2 A;  1WPY A;  4PHC A;  1SRY A;  5ELO A;  4CS3 A;  4O2D A;  1USY C;  1ADJ A;  2E3C A;  4YRC A;  1YFR A;  3V7R A;  3QTC A;  2ZZG A;  1G5H A;  3P8Y A;  3UFG A;  2HNI A;  2Q5H A;  3FJP A;  1PYS A;  3HXY A;  4YPF A;  1KOG A;  3P8V A;  4K86 A;  1B7Y A;  3A5Y A;  4P74 C;  3HXX A;  3L2Z A;  5E3I A;  2IY5 B;  3E9I A;  2DTI A;  2DQ0 A;  3NEN A;  3HY0 A;  4H2X A;  2DU5 A;  4AH6 A;  2RHQ A;  2ZIM A;  2ZIO A;  2I4O A;  3RIR A;  1YFT A;  1ATI A;  2AKW B;  1JJC B;  4H02 A;  3A32 A;  2EWN A;  3HY1 A;  4KR3 A;  3M4Q A;  4XTZ A;  3HFV A;  3QO8 A;  1N9W A;  4P3O A;  3TEG A;  4Q15 A;  4TWA A;  4XTX A;  2DJZ A;  4HA8 A;  1FYF A;  4Q6G A;  1NYQ A;  4YCU A;  4RQE A;  1B7Y B;  1Z7M A;  3R07 A;  4HWP A;  1NJ5 A;  4TVY A;  3IG2 A;  4XU3 A;  4YRF A;  2DDZ A;  3L4G A;  4YYE A;  4HWS A; 
#chains in the Genus database with same CATH topology
 2EAY A;  2RHQ B;  3EFS A;  1EFW A;  1C0A A;  2Q7H A;  4RQF A;  3M4P A;  2ALY A;  2I4L A;  5C51 B;  4WJ3 M;  4YRI A;  2RHS A;  4L87 A;  2Q7E A;  2DZ9 A;  3G1Z A;  4P3N A;  3BJU A;  1EOV A;  3QO5 A;  4YRQ A;  4EO4 A;  2DKG A;  4DPG A;  2ODR D;  4E51 A;  4YRJ A;  4XEM A;  1IL2 A;  3V7S A;  4YCW A;  2CJ9 A;  3HRK A;  4K88 A;  3VQY A;  4ZIB A;  2DTH A;  4H2V A;  3RAC A;  1EIY B;  3L4G B;  4HT4 A;  4XU0 A;  1EVK A;  4YRN A;  2ZR3 A;  3VQX A;  2E1H A;  3EFR A;  4OP0 A;  1HXD A;  2ALY B;  1SET A;  2RHS B;  1E22 A;  4P73 A;  4YRO A;  3VQW A;  4CH5 A;  1X2G A;  1SES A;  4LNS A;  12AS A;  2AMC A;  4UPA A;  4P72 A;  4YRM A;  1B70 A;  3I7F A;  3WQZ A;  3UGQ A;  3UH0 A;  5K1X A;  2EJ9 A;  2J3M A;  3ICA A;  3IKM B;  4TVA A;  4H2S A;  2ZXF A;  4YRE A;  4YRS A;  3NEL A;  4BWA A;  11AS A;  3L1A A;  4XTY A;  2QHS A;  1W66 A;  4YRT A;  4RMF A;  4TQD A;  1BBW A;  4PG3 A;  3LSS A;  4WJ4 A;  3MEY A;  1NJ8 A;  4XU1 A;  3CMQ A;  4XU2 A;  3REU A;  3RKW A;  2PME A;  2AMC B;  2I4N A;  3HFZ A;  1WLE A;  2CGH A;  5F5W A;  3VQV A;  3V7C A;  1HC7 A;  3A74 A;  1X56 A;  4TVA B;  2QHT A;  1PYS B;  4X5O A;  3A5Z A;  1L0W A;  3TEH A;  2ZR2 A;  1NNH A;  1VQZ A;  2ART A;  4YRP A;  4DQ2 A;  2EJF A;  4HWT A;  1X54 A;  1ASY A;  4YRG A;  3DSQ A;  4YRR A;  3QO7 A;  2ZT7 A;  1EVL A;  3RUX A;  4P73 C;  1J5W A;  2DEQ A;  5ELN A;  2DTO A;  4P3P A;  4H2W A;  1KMN A;  2EL9 A;  2DU7 A;  2Q5I A;  4YP0 A;  3VBB A;  1WQW A;  4YCV A;  4K87 A;  3RL6 A;  1BBU A;  3IKL A;  4CH4 A;  2ZZE A;  1NJ2 A;  3A7U A;  3PZC A;  4TTV A;  4P71 A;  1X01 A;  2DXT A;  1E1O A;  3V8J A;  2ZT8 A;  1WYD A;  2ZGW A;  1NJ1 A;  2ARU A;  4TQF A;  4H2Y A;  3TUP A;  1G5I A;  2DQ3 A;  2FYK A;  2Q7G A;  3MF1 A;  4P75 A;  2I4M A;  2E64 A;  2C7I A;  1WQ7 A;  4H2U A;  3RGL A;  4KR2 A;  3HXU A;  4LVI A;  4HWO A;  1YFS A;  5KNN A;  1Z7N A;  3HXV A;  4TVW A;  3V8K A;  4G85 A;  5HGQ A;  2QHV A;  3HXZ A;  4UP9 A;  2E10 A;  4LVM A;  1JJC A;  2EJG A;  3KFU A;  1WNL A;  2G4C A;  3RKY A;  1H4T A;  3QNE A;  4J15 A;  1YGB A;  2ZZF A;  3RKX A;  3UGT A;  2J3L A;  3NET A;  4YRK A;  3ERR A;  4WI1 A;  2CJB A;  4BW9 A;  5C52 B;  3A31 A;  1GGM A;  3RF1 A;  4P71 C;  1E24 A;  3IAL A;  4UP8 A;  1B70 B;  1QE0 A;  2CJA A;  4CH3 A;  4ZTU B;  4OLF A;  1H4S A;  1X2H A;  2XGT A;  4EX5 A;  4P75 C;  4CH6 A;  2DXU A;  4XTU A;  4XEO A;  3A7R A;  1E1T A;  5K1P A;  3W3S A;  1USY A;  2E41 A;  4NCX A;  3E9H A;  2CIM A;  2XTI A;  1NJ6 A;  4HVC A;  3BFM A;  2ZNJ A;  1WU7 A;  3REX A;  4P72 C;  1KMM A;  3LC0 A;  4HWR A;  4YRL A;  2ZTG A;  2ZNI A;  4H2X B;  1EIY A;  4XTV A;  2ZT5 A;  2P5I A;  3P8T A;  3HFZ B;  2P0L A;  4P74 A;  2C8M A;  4UP7 A;  4XTW A;  3V8L A;  4CS4 A;  2E5A A;  1B8A A;  3HRI A;  1SER A;  3HXW A;  4H2T A;  1H4V B;  3TEH B;  1B76 A;  3LSQ A;  1EQR A;  3OD1 A;  3PCO A;  2DZC A;  2ODR C;  2ZT6 A;  1X55 A;  1YB3 A;  2NS6 A;  2ZIN A;  4RDX A;  1RIQ A;  2ZCE A;  1ASZ A;  3MF2 A;  1BIB A;  4WF2 A;  1NYR A;  2QHU A;  2DVE A;  1QF6 A;  3A7A A;  1HTT A;  2IY5 A;  3HTZ A;  4ZTZ B;  1G51 A;  2PMF A;  4G84 A;  1BIA A;  3MQZ A;  5C53 B;  1H4Q A;  2A8E A;  2E65 A;  1ADY A;  4KQE A;  1LYL A;  2ARS A;  2AKW A;  4YDQ A;  3NEM A;  3PCO B;  4CS2 A;  1WPY A;  4PHC A;  1SRY A;  5ELO A;  4CS3 A;  4O2D A;  1USY C;  1ADJ A;  2E3C A;  4YRC A;  1YFR A;  3V7R A;  3QTC A;  2ZZG A;  1G5H A;  3P8Y A;  3UFG A;  2HNI A;  2Q5H A;  3FJP A;  4LVL A;  1PYS A;  3HXY A;  4YPF A;  1KOG A;  3P8V A;  4K86 A;  1B7Y A;  3A5Y A;  4P74 C;  3HXX A;  3L2Z A;  5E3I A;  2IY5 B;  3E9I A;  2DTI A;  2DQ0 A;  3NEN A;  3HY0 A;  4H2X A;  2DU5 A;  4LVK A;  4AH6 A;  2RHQ A;  2ZIM A;  2ZIO A;  2I4O A;  3RIR A;  1YFT A;  1ATI A;  2AKW B;  1JJC B;  4H02 A;  3A32 A;  2EWN A;  3HY1 A;  4KR3 A;  3M4Q A;  4XTZ A;  3HFV A;  3QO8 A;  1N9W A;  4P3O A;  3TEG A;  4Q15 A;  4TWA A;  4XTX A;  4LVJ A;  2DJZ A;  4HA8 A;  1FYF A;  4Q6G A;  1NYQ A;  4YCU A;  4RQE A;  1B7Y B;  1Z7M A;  3R07 A;  4HWP A;  1NJ5 A;  4TVY A;  3IG2 A;  4XU3 A;  4YRF A;  2DDZ A;  3L4G A;  4YYE A;  4HWS A; 
#chains in the Genus database with same CATH homology
 2EAY A;  2RHQ B;  3EFS A;  1EFW A;  1C0A A;  2Q7H A;  4RQF A;  3M4P A;  2ALY A;  2I4L A;  5C51 B;  4WJ3 M;  4YRI A;  2RHS A;  4L87 A;  2Q7E A;  2DZ9 A;  3G1Z A;  4P3N A;  3BJU A;  1EOV A;  3QO5 A;  4YRQ A;  4EO4 A;  2DKG A;  4DPG A;  2ODR D;  4E51 A;  4YRJ A;  4XEM A;  1IL2 A;  3V7S A;  4YCW A;  2CJ9 A;  3HRK A;  4K88 A;  3VQY A;  4ZIB A;  2DTH A;  4H2V A;  3RAC A;  1EIY B;  3L4G B;  4HT4 A;  4XU0 A;  1EVK A;  4YRN A;  2ZR3 A;  3VQX A;  2E1H A;  3EFR A;  4OP0 A;  1HXD A;  2ALY B;  1SET A;  2RHS B;  1E22 A;  4P73 A;  4YRO A;  3VQW A;  4CH5 A;  1X2G A;  1SES A;  4LNS A;  12AS A;  2AMC A;  4UPA A;  4P72 A;  4YRM A;  1B70 A;  3I7F A;  3WQZ A;  3UGQ A;  3UH0 A;  5K1X A;  2EJ9 A;  2J3M A;  3ICA A;  3IKM B;  4TVA A;  4H2S A;  2ZXF A;  4YRE A;  4YRS A;  3NEL A;  4BWA A;  11AS A;  3L1A A;  4XTY A;  2QHS A;  1W66 A;  4YRT A;  4RMF A;  4TQD A;  1BBW A;  4PG3 A;  3LSS A;  4WJ4 A;  3MEY A;  1NJ8 A;  4XU1 A;  3CMQ A;  4XU2 A;  3REU A;  3RKW A;  2PME A;  2AMC B;  2I4N A;  3HFZ A;  1WLE A;  2CGH A;  5F5W A;  3VQV A;  3V7C A;  1HC7 A;  3A74 A;  1X56 A;  4TVA B;  2QHT A;  1PYS B;  4X5O A;  3A5Z A;  1L0W A;  3TEH A;  2ZR2 A;  1NNH A;  1VQZ A;  2ART A;  4YRP A;  4DQ2 A;  2EJF A;  4HWT A;  1X54 A;  1ASY A;  4YRG A;  3DSQ A;  4YRR A;  3QO7 A;  2ZT7 A;  1EVL A;  3RUX A;  4P73 C;  1J5W A;  2DEQ A;  5ELN A;  2DTO A;  4P3P A;  4H2W A;  1KMN A;  2EL9 A;  2DU7 A;  2Q5I A;  4YP0 A;  3VBB A;  1WQW A;  4YCV A;  4K87 A;  3RL6 A;  1BBU A;  3IKL A;  4CH4 A;  2ZZE A;  1NJ2 A;  3A7U A;  3PZC A;  4TTV A;  4P71 A;  1X01 A;  2DXT A;  1E1O A;  3V8J A;  2ZT8 A;  1WYD A;  2ZGW A;  1NJ1 A;  2ARU A;  4TQF A;  4H2Y A;  3TUP A;  1G5I A;  2DQ3 A;  2FYK A;  2Q7G A;  3MF1 A;  4P75 A;  2I4M A;  2E64 A;  2C7I A;  1WQ7 A;  4H2U A;  3RGL A;  4KR2 A;  3HXU A;  4LVI A;  4HWO A;  1YFS A;  5KNN A;  1Z7N A;  3HXV A;  4TVW A;  3V8K A;  4G85 A;  5HGQ A;  2QHV A;  3HXZ A;  4UP9 A;  2E10 A;  4LVM A;  1JJC A;  2EJG A;  3KFU A;  1WNL A;  2G4C A;  3RKY A;  1H4T A;  3QNE A;  4J15 A;  1YGB A;  2ZZF A;  3RKX A;  3UGT A;  2J3L A;  3NET A;  4YRK A;  3ERR A;  4WI1 A;  2CJB A;  4BW9 A;  5C52 B;  3A31 A;  1GGM A;  3RF1 A;  4P71 C;  1E24 A;  3IAL A;  4UP8 A;  1B70 B;  1QE0 A;  2CJA A;  4CH3 A;  4ZTU B;  4OLF A;  1H4S A;  1X2H A;  2XGT A;  4EX5 A;  4P75 C;  4CH6 A;  2DXU A;  4XTU A;  4XEO A;  3A7R A;  1E1T A;  5K1P A;  3W3S A;  1USY A;  2E41 A;  4NCX A;  3E9H A;  2CIM A;  2XTI A;  1NJ6 A;  4HVC A;  3BFM A;  2ZNJ A;  1WU7 A;  3REX A;  4P72 C;  1KMM A;  3LC0 A;  4HWR A;  4YRL A;  2ZTG A;  2ZNI A;  4H2X B;  1EIY A;  4XTV A;  2ZT5 A;  2P5I A;  3P8T A;  3HFZ B;  2P0L A;  4P74 A;  2C8M A;  4UP7 A;  4XTW A;  3V8L A;  4CS4 A;  2E5A A;  1B8A A;  3HRI A;  1SER A;  3HXW A;  4H2T A;  1H4V B;  3TEH B;  1B76 A;  3LSQ A;  1EQR A;  3OD1 A;  3PCO A;  2DZC A;  2ODR C;  2ZT6 A;  1X55 A;  1YB3 A;  2NS6 A;  2ZIN A;  4RDX A;  1RIQ A;  2ZCE A;  1ASZ A;  3MF2 A;  1BIB A;  4WF2 A;  1NYR A;  2QHU A;  2DVE A;  1QF6 A;  3A7A A;  1HTT A;  2IY5 A;  3HTZ A;  4ZTZ B;  1G51 A;  2PMF A;  4G84 A;  1BIA A;  3MQZ A;  5C53 B;  1H4Q A;  2A8E A;  2E65 A;  1ADY A;  4KQE A;  1LYL A;  2ARS A;  2AKW A;  4YDQ A;  3NEM A;  3PCO B;  4CS2 A;  1WPY A;  4PHC A;  1SRY A;  5ELO A;  4CS3 A;  4O2D A;  1USY C;  1ADJ A;  2E3C A;  4YRC A;  1YFR A;  3V7R A;  3QTC A;  2ZZG A;  1G5H A;  3P8Y A;  3UFG A;  2HNI A;  2Q5H A;  3FJP A;  4LVL A;  1PYS A;  3HXY A;  4YPF A;  1KOG A;  3P8V A;  4K86 A;  1B7Y A;  3A5Y A;  4P74 C;  3HXX A;  3L2Z A;  5E3I A;  2IY5 B;  3E9I A;  2DTI A;  2DQ0 A;  3NEN A;  3HY0 A;  4H2X A;  2DU5 A;  4LVK A;  4AH6 A;  2RHQ A;  2ZIM A;  2ZIO A;  2I4O A;  3RIR A;  1YFT A;  1ATI A;  2AKW B;  1JJC B;  4H02 A;  3A32 A;  2EWN A;  3HY1 A;  4KR3 A;  3M4Q A;  4XTZ A;  3HFV A;  3QO8 A;  1N9W A;  4P3O A;  3TEG A;  4Q15 A;  4TWA A;  4XTX A;  4LVJ A;  2DJZ A;  4HA8 A;  1FYF A;  4Q6G A;  1NYQ A;  4YCU A;  4RQE A;  1B7Y B;  1Z7M A;  3R07 A;  4HWP A;  1NJ5 A;  4TVY A;  3IG2 A;  4XU3 A;  4YRF A;  2DDZ A;  3L4G A;  4YYE A;  4HWS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...