The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
90
|
sequence length |
316
|
structure length |
294
|
Chain Sequence |
KDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRSPFGANLYLSMFWRLEQPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGAAQIVIGAGINMAMWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains.
pubmed doi rcsb |
| molecule tags |
Transcription regulation
|
| source organism |
Escherichia coli
|
| molecule keywords |
BIR A
|
| total genus |
90
|
| structure length |
294
|
| sequence length |
316
|
| ec nomenclature |
ec
6.3.4.15: Biotin--[biotin carboxyl-carrier protein] ligase. |
| pdb deposition date | 1992-07-06 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02237 | BPL_C | Biotin protein ligase C terminal domain |
| A | PF03099 | BPL_LplA_LipB | Biotin/lipoate A/B protein ligase family |
| A | PF08279 | HTH_11 | HTH domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Arc Repressor Mutant, subunit A | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | ||
| Mainly Beta | Roll | SH3 type barrels. | SH3 type barrels. | ||
| Alpha Beta | 2-Layer Sandwich | BirA Bifunctional Protein; domain 2 | Bira Bifunctional Protein; Domain 2 |
