5KNNA

Evolutionary gain of alanine mischarging to non-cognate trnas with a g4:u69 base pair
Total Genus 154
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
sequence length
450
structure length
450
Chain Sequence
TLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
molecule keywords Alanine--tRNA ligase, cytoplasmic
publication title Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair.
pubmed doi rcsb
source organism Homo sapiens
total genus 154
structure length 450
sequence length 450
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 6.1.1.7: Alanine--tRNA ligase.
pdb deposition date 2016-06-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.930.10 Alpha Beta 2-Layer Sandwich BirA Bifunctional Protein; domain 2 Bira Bifunctional Protein; Domain 2 5knnA01
1WLEA 1PYSA 2XGTA 3L4GB 3V7SA 2EJGA 3HY0A 2AKWA 4TVWA 2QHTA 3E9IA 4TQDA 1YGBA 3V8KA 2CJAA 3P8YA 3OD1A 4RMFA 4TQFA 4P75A 3LSQA 4H2UA 3HXYA 3IALA 4DPGA 2IY5B 2AMCA 2ARUA 1SETA 4YRFA 4YRIA 4CS2A 3EFRA 2RHSA 4KR2A 4P3PA 1ASYA 3TUPA 2ZZFA 3QTCA 4P74C 2ZINA 1X2GA 3HXZA 3RUXA 3LSSA 4YREA 1JJCB 4AH6A 4G85A 4H2YA 2ZCEA 3HTZA 1B70B 3IG2A 5C53B 1E1OA 3HRIA 3NEMA 4YRNA 1G5IA 5K1PA 2P5IA 1EIYB 5C51B 3VQXA 1KOGA 4K87A 2ZIOA 1EFWA 2DVEA 3REUA 2E3CA 4LNSA 4WI1A 4YP0A 3RKWA 2HNIA 2EWNA 3IKMB 3G1ZA 3M4PA 4ZTUB 3V8JA 1W66A 1H4SA 4XTVA 4YRSA 2ZZEA 4XTXA 4YCWA 2ZTGA 3TEHB 4H2XB 2J3LA 1Z7NA 2QHUA 3V7RA 4H2TA 3HFZA 1YB3A 2DJZA 2ODRC 2CIMA 1QE0A 2Q5IA 3UFGA 4P3NA 2ZGWA 4CH3A 2DDZA 2QHSA 1ADJA 4KQEA 1C0AA 4HVCA 4YRLA 1WQWA 2E41A 2RHQA 4HWPA 3VBBA 3IKLA 2E1HA 1H4TA 4P71A 3W3SA 1WNLA 3MEYA 2XTIA 4XU2A 1EVLA 4YRTA 1BBWA 4TVAB 4WJ4A 1NJ6A 1KMNA 2EJFA 3ERRA 1X56A 3L4GA 4H2SA 4XEOA 2EAYA 1G51A 2I4NA 2ZZGA 3A7AA 4RDXA 4P75C 1NNHA 2DEQA 2ARTA 3A32A 4P72A 4CH6A 3HXVA 3HXWA 3WQZA 4XTYA 3RKXA 3E9HA 2P0LA 1HTTA 2ARSA 1YFTA 2CGHA 3L1AA 2CJ9A 2FYKA 1PYSB 4Q15A 1QF6A 4UPAA 2DU7A 1WU7A 4P73A 4YPFA 4E51A 3NELA 2I4OA 1YFRA 4G84A 2E65A 2AKWB 3KFUA 1JJCA 3R07A 3A5ZA 1YFSA 2Q7HA 3VQWA 2DKGA 4Q6GA 4NCXA 4YCUA 3M4QA 1B70A 1USYA 2QHVA 3A5YA 3A74A 4XEMA 2ZIMA 4ZTZB 1BIAA 3V7CA 3UH0A 3QO7A 1EIYA 4HWOA 3L2ZA 4OP0A 3BFMA 3UGQA 2DZ9A 2ZR3A 4CS3A 1FYFA 4PHCA 4YRJA 3QO8A 3RKYA 1ASZA 3HY1A 2ZNIA 1NYRA 1HXDA 4H2WA 4J15A 2DTOA 3BJUA 1EQRA 11ASA 5K1XA 3TEGA 1Z7MA 4H02A 1SRYA 4YRMA 1EOVA 1NYQA 1X2HA 1SERA 4H2XA 4PG3A 4YDQA 4K88A 4HA8A 3HFVA 1B7YA 4H2VA 4YRQA 1VQZA 2ALYA 2EJ9A 4DQ2A 2DQ3A 3V8LA 3EFSA 4P71C 4HWRA 4XU1A 4RQFA 2ZNJA 3PCOB 4YRKA 3RIRA 4YROA 5E3IA 1SESA 3RL6A 4WF2A 4CH5A 4CS4A 1WYDA 1X01A 2CJBA 1RIQA 3PZCA 4BW9A 4TVYA 1ADYA 3HFZB 1GGMA 4YRGA 4TWAA 5ELOA 4P72C 2DU5A 2DZCA 2DXUA 2C8MA 3VQYA 3VQVA 4RQEA 1X55A 1G5HA 4YRPA 5KNNA 5HGQA 4P73C 2PMEA 2DXTA 2IY5A 4YRCA 4OLFA 4O2DA 3REXA 2E5AA 4ZIBA 1L0WA 1USYC 3RGLA 1IL2A 1BIBA 3I7FA 4XTUA 2ZT6A 3MF1A 4YRRA 1WPYA 2Q5HA 3A31A 1E1TA 1EVKA 3P8TA 2AMCB 1WQ7A 2DQ0A 1E24A 3RACA 4XTZA 2RHSB 2DTHA 3LC0A 5C52B 2EL9A 5F5WA 1N9WA 3QNEA 4UP8A 3RF1A 4X5OA 2Q7GA 4P74A 1NJ2A 2E64A 3NENA 2DTIA 4BWAA 4HWTA 2PMFA 3TEHA 4KR3A 3CMQA 3NETA 3UGTA 2Q7EA 3A7RA 3A7UA 2E10A 3P8VA 4CH4A 1LYLA 1E22A 3ICAA 1B8AA 3HRKA 4YCVA 4XU0A 12ASA 3PCOA 1NJ1A 2I4MA 4XTWA 4XU3A 2J3MA 4UP7A 2ODRD 1BBUA 2ZT7A 1B7YB 3HXXA 1HC7A 1B76A 2ALYB 4K86A 3HXUA 1KMMA 5ELNA 4YYEA 4TVAA 4P3OA 2C7IA 2ZT8A 1H4QA 1NJ8A 4WJ3M 3MF2A 4EX5A 1ATIA 1NJ5A 2G4CA 2RHQB 4L87A 4TTVA 4UP9A 2ZR2A 4HWSA 4EO4A 2ZXFA 2ZT5A 3FJPA 3QO5A 1X54A 2I4LA 1J5WA 3DSQA 1H4VB
chains in the Genus database with same CATH superfamily
1WLEA 1PYSA 2XGTA 3L4GB 3V7SA 2EJGA 3HY0A 2AKWA 4TVWA 2QHTA 3E9IA 4TQDA 1YGBA 3V8KA 2CJAA 3P8YA 3OD1A 4RMFA 4TQFA 4P75A 3LSQA 4H2UA 3HXYA 3IALA 4DPGA 2IY5B 2AMCA 2ARUA 1SETA 4YRFA 4YRIA 4CS2A 3EFRA 2RHSA 4KR2A 4P3PA 1ASYA 3TUPA 2ZZFA 3QTCA 4P74C 2ZINA 1X2GA 3HXZA 3RUXA 3LSSA 4YREA 1JJCB 4AH6A 4G85A 4H2YA 2ZCEA 3HTZA 1B70B 3IG2A 5C53B 1E1OA 3HRIA 3NEMA 4YRNA 1G5IA 5K1PA 2P5IA 1EIYB 5C51B 3VQXA 1KOGA 4K87A 2ZIOA 1EFWA 2DVEA 3REUA 2E3CA 4LNSA 4WI1A 4YP0A 3RKWA 2HNIA 2EWNA 3IKMB 3G1ZA 3M4PA 4ZTUB 3V8JA 1W66A 1H4SA 4XTVA 4YRSA 2ZZEA 4LVLA 4XTXA 4YCWA 2ZTGA 3TEHB 4H2XB 2J3LA 1Z7NA 2QHUA 3V7RA 4H2TA 3HFZA 1YB3A 2DJZA 2ODRC 2CIMA 1QE0A 2Q5IA 3UFGA 4P3NA 2ZGWA 4CH3A 2DDZA 2QHSA 1ADJA 4KQEA 1C0AA 4HVCA 4YRLA 1WQWA 2E41A 2RHQA 4HWPA 2NS6A 3VBBA 3IKLA 2E1HA 1H4TA 4P71A 3W3SA 1WNLA 4LVMA 3MEYA 2XTIA 4XU2A 1EVLA 4YRTA 1BBWA 4TVAB 4WJ4A 1NJ6A 1KMNA 2EJFA 3ERRA 1X56A 3L4GA 4H2SA 4XEOA 2EAYA 1G51A 2I4NA 2ZZGA 3A7AA 4RDXA 4P75C 1NNHA 2DEQA 2ARTA 3A32A 4P72A 4CH6A 3HXVA 3HXWA 3WQZA 4XTYA 3RKXA 3E9HA 2P0LA 1HTTA 2ARSA 1YFTA 2CGHA 3L1AA 4LVJA 2CJ9A 2FYKA 1PYSB 4Q15A 1QF6A 4UPAA 2DU7A 1WU7A 4P73A 4YPFA 4E51A 3NELA 2I4OA 1YFRA 4G84A 2E65A 2AKWB 3KFUA 1JJCA 3R07A 3A5ZA 1YFSA 2Q7HA 3VQWA 2DKGA 4Q6GA 4NCXA 4YCUA 3M4QA 1B70A 1USYA 2QHVA 3A5YA 3A74A 4XEMA 2ZIMA 4ZTZB 1BIAA 3V7CA 3UH0A 3QO7A 1EIYA 4HWOA 3L2ZA 4OP0A 3BFMA 3MQZA 3UGQA 2DZ9A 2ZR3A 4CS3A 1FYFA 4PHCA 4YRJA 3QO8A 3RKYA 1ASZA 3HY1A 2ZNIA 1NYRA 1HXDA 4H2WA 4J15A 2DTOA 3BJUA 1EQRA 11ASA 5K1XA 3TEGA 1Z7MA 4H02A 1SRYA 4YRMA 1EOVA 1NYQA 1X2HA 1SERA 4H2XA 4PG3A 4YDQA 4K88A 4HA8A 3HFVA 1B7YA 4H2VA 4YRQA 1VQZA 2ALYA 2EJ9A 4DQ2A 2DQ3A 3V8LA 4HT4A 3EFSA 4P71C 4HWRA 4XU1A 4RQFA 2ZNJA 3PCOB 4YRKA 3RIRA 4YROA 5E3IA 1SESA 3RL6A 4WF2A 4CH5A 4CS4A 1WYDA 1X01A 2CJBA 1RIQA 3PZCA 4BW9A 4TVYA 1ADYA 3HFZB 1GGMA 4YRGA 4TWAA 5ELOA 4P72C 2DU5A 2DZCA 2DXUA 2C8MA 3VQYA 3VQVA 4RQEA 1X55A 1G5HA 4YRPA 5KNNA 5HGQA 4LVIA 4P73C 2PMEA 2DXTA 2IY5A 4YRCA 4OLFA 4O2DA 3REXA 2E5AA 4ZIBA 1L0WA 1USYC 3RGLA 1IL2A 1BIBA 3I7FA 4XTUA 2ZT6A 3MF1A 4YRRA 1WPYA 2Q5HA 4LVKA 3A31A 1E1TA 1EVKA 3P8TA 2AMCB 1WQ7A 2DQ0A 1E24A 3RACA 4XTZA 2RHSB 2DTHA 3LC0A 5C52B 2EL9A 5F5WA 1N9WA 3QNEA 4UP8A 3RF1A 4X5OA 2Q7GA 4P74A 1NJ2A 2A8EA 2E64A 3NENA 2DTIA 4BWAA 4HWTA 2PMFA 3TEHA 4KR3A 3CMQA 3NETA 3UGTA 2Q7EA 3A7RA 3A7UA 2E10A 3P8VA 4CH4A 1LYLA 1E22A 3ICAA 1B8AA 3HRKA 4YCVA 4XU0A 12ASA 3PCOA 1NJ1A 2I4MA 4XTWA 4XU3A 2J3MA 4UP7A 2ODRD 1BBUA 2ZT7A 1B7YB 3HXXA 1HC7A 1B76A 2ALYB 4K86A 3HXUA 1KMMA 5ELNA 4YYEA 4TVAA 4P3OA 2C7IA 2ZT8A 1H4QA 1NJ8A 4WJ3M 3MF2A 4EX5A 1ATIA 1NJ5A 2G4CA 2RHQB 4L87A 4TTVA 4UP9A 2ZR2A 4HWSA 4EO4A 2ZXFA 2ZT5A 3FJPA 3QO5A 1X54A 2I4LA 1J5WA 3DSQA 1H4VB
chains in the Genus database with same CATH topology
1WLEA 1PYSA 2XGTA 3L4GB 3V7SA 2EJGA 3HY0A 2AKWA 4TVWA 2QHTA 3E9IA 4TQDA 1YGBA 3V8KA 2CJAA 3P8YA 3OD1A 4RMFA 4TQFA 4P75A 3LSQA 4H2UA 3HXYA 3IALA 4DPGA 2IY5B 2AMCA 2ARUA 1SETA 4YRFA 4YRIA 4CS2A 3EFRA 2RHSA 4KR2A 4P3PA 1ASYA 3TUPA 2ZZFA 3QTCA 4P74C 2ZINA 1X2GA 3HXZA 3RUXA 3LSSA 4YREA 1JJCB 4AH6A 4G85A 4H2YA 2ZCEA 3HTZA 1B70B 3IG2A 5C53B 1E1OA 3HRIA 3NEMA 4YRNA 1G5IA 5K1PA 2P5IA 1EIYB 5C51B 3VQXA 1KOGA 4K87A 2ZIOA 1EFWA 2DVEA 3REUA 2E3CA 4LNSA 4WI1A 4YP0A 3RKWA 2HNIA 2EWNA 3IKMB 3G1ZA 3M4PA 4ZTUB 3V8JA 1W66A 1H4SA 4XTVA 4YRSA 2ZZEA 4LVLA 4XTXA 4YCWA 2ZTGA 3TEHB 4H2XB 2J3LA 1Z7NA 2QHUA 3V7RA 4H2TA 3HFZA 1YB3A 2DJZA 2ODRC 2CIMA 1QE0A 2Q5IA 3UFGA 4P3NA 2ZGWA 4CH3A 2DDZA 2QHSA 1ADJA 4KQEA 1C0AA 4HVCA 4YRLA 1WQWA 2E41A 2RHQA 4HWPA 2NS6A 3VBBA 3IKLA 2E1HA 1H4TA 4P71A 3W3SA 1WNLA 4LVMA 3MEYA 2XTIA 4XU2A 1EVLA 4YRTA 1BBWA 4TVAB 4WJ4A 1NJ6A 1KMNA 2EJFA 3ERRA 1X56A 3L4GA 4H2SA 4XEOA 2EAYA 1G51A 2I4NA 2ZZGA 3A7AA 4RDXA 4P75C 1NNHA 2DEQA 2ARTA 3A32A 4P72A 4CH6A 3HXVA 3HXWA 3WQZA 4XTYA 3RKXA 3E9HA 2P0LA 1HTTA 2ARSA 1YFTA 2CGHA 3L1AA 4LVJA 2CJ9A 2FYKA 1PYSB 4Q15A 1QF6A 4UPAA 2DU7A 1WU7A 4P73A 4YPFA 4E51A 3NELA 2I4OA 1YFRA 4G84A 2E65A 2AKWB 3KFUA 1JJCA 3R07A 3A5ZA 1YFSA 2Q7HA 3VQWA 2DKGA 4Q6GA 4NCXA 4YCUA 3M4QA 1B70A 1USYA 2QHVA 3A5YA 3A74A 4XEMA 2ZIMA 4ZTZB 1BIAA 3V7CA 3UH0A 3QO7A 1EIYA 4HWOA 3L2ZA 4OP0A 3BFMA 3MQZA 3UGQA 2DZ9A 2ZR3A 4CS3A 1FYFA 4PHCA 4YRJA 3QO8A 3RKYA 1ASZA 3HY1A 2ZNIA 1NYRA 1HXDA 4H2WA 4J15A 2DTOA 3BJUA 1EQRA 11ASA 5K1XA 3TEGA 1Z7MA 4H02A 1SRYA 4YRMA 1EOVA 1NYQA 1X2HA 1SERA 4H2XA 4PG3A 4YDQA 4K88A 4HA8A 3HFVA 1B7YA 4H2VA 4YRQA 1VQZA 2ALYA 2EJ9A 4DQ2A 2DQ3A 3V8LA 4HT4A 3EFSA 4P71C 4HWRA 4XU1A 4RQFA 2ZNJA 3PCOB 4YRKA 3RIRA 4YROA 5E3IA 1SESA 3RL6A 4WF2A 4CH5A 4CS4A 1WYDA 1X01A 2CJBA 1RIQA 3PZCA 4BW9A 4TVYA 1ADYA 3HFZB 1GGMA 4YRGA 4TWAA 5ELOA 4P72C 2DU5A 2DZCA 2DXUA 2C8MA 3VQYA 3VQVA 4RQEA 1X55A 1G5HA 4YRPA 5KNNA 5HGQA 4LVIA 4P73C 2PMEA 2DXTA 2IY5A 4YRCA 4OLFA 4O2DA 3REXA 2E5AA 4ZIBA 1L0WA 1USYC 3RGLA 1IL2A 1BIBA 3I7FA 4XTUA 2ZT6A 3MF1A 4YRRA 1WPYA 2Q5HA 4LVKA 3A31A 1E1TA 1EVKA 3P8TA 2AMCB 1WQ7A 2DQ0A 1E24A 3RACA 4XTZA 2RHSB 2DTHA 3LC0A 5C52B 2EL9A 5F5WA 1N9WA 3QNEA 4UP8A 3RF1A 4X5OA 2Q7GA 4P74A 1NJ2A 2A8EA 2E64A 3NENA 2DTIA 4BWAA 4HWTA 2PMFA 3TEHA 4KR3A 3CMQA 3NETA 3UGTA 2Q7EA 3A7RA 3A7UA 2E10A 3P8VA 4CH4A 1LYLA 1E22A 3ICAA 1B8AA 3HRKA 4YCVA 4XU0A 12ASA 3PCOA 1NJ1A 2I4MA 4XTWA 4XU3A 2J3MA 4UP7A 2ODRD 1BBUA 2ZT7A 1B7YB 3HXXA 1HC7A 1B76A 2ALYB 4K86A 3HXUA 1KMMA 5ELNA 4YYEA 4TVAA 4P3OA 2C7IA 2ZT8A 1H4QA 1NJ8A 4WJ3M 3MF2A 4EX5A 1ATIA 1NJ5A 2G4CA 2RHQB 4L87A 4TTVA 4UP9A 2ZR2A 4HWSA 4EO4A 2ZXFA 2ZT5A 3FJPA 3QO5A 1X54A 2I4LA 1J5WA 3DSQA 1H4VB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WLE A;  1PYS A;  2XGT A;  3L4G B;  3V7S A;  2EJG A;  3HY0 A;  2AKW A;  4TVW A;  2QHT A;  3E9I A;  4TQD A;  1YGB A;  3V8K A;  2CJA A;  3P8Y A;  3OD1 A;  4RMF A;  4TQF A;  4P75 A;  3LSQ A;  4H2U A;  3HXY A;  3IAL A;  4DPG A;  2IY5 B;  2AMC A;  2ARU A;  1SET A;  4YRF A;  4YRI A;  4CS2 A;  3EFR A;  2RHS A;  4KR2 A;  4P3P A;  1ASY A;  3TUP A;  2ZZF A;  3QTC A;  4P74 C;  2ZIN A;  1X2G A;  3HXZ A;  3RUX A;  3LSS A;  4YRE A;  1JJC B;  4AH6 A;  4G85 A;  4H2Y A;  2ZCE A;  3HTZ A;  1B70 B;  3IG2 A;  5C53 B;  1E1O A;  3HRI A;  3NEM A;  4YRN A;  1G5I A;  5K1P A;  2P5I A;  1EIY B;  5C51 B;  3VQX A;  1KOG A;  4K87 A;  2ZIO A;  1EFW A;  2DVE A;  3REU A;  2E3C A;  4LNS A;  4WI1 A;  4YP0 A;  3RKW A;  2HNI A;  2EWN A;  3IKM B;  3G1Z A;  3M4P A;  4ZTU B;  3V8J A;  1W66 A;  1H4S A;  4XTV A;  4YRS A;  2ZZE A;  4XTX A;  4YCW A;  2ZTG A;  3TEH B;  4H2X B;  2J3L A;  1Z7N A;  2QHU A;  3V7R A;  4H2T A;  3HFZ A;  1YB3 A;  2DJZ A;  2ODR C;  2CIM A;  1QE0 A;  2Q5I A;  3UFG A;  4P3N A;  2ZGW A;  4CH3 A;  2DDZ A;  2QHS A;  1ADJ A;  4KQE A;  1C0A A;  4HVC A;  4YRL A;  1WQW A;  2E41 A;  2RHQ A;  4HWP A;  3VBB A;  3IKL A;  2E1H A;  1H4T A;  4P71 A;  3W3S A;  1WNL A;  3MEY A;  2XTI A;  4XU2 A;  1EVL A;  4YRT A;  1BBW A;  4TVA B;  4WJ4 A;  1NJ6 A;  1KMN A;  2EJF A;  3ERR A;  1X56 A;  3L4G A;  4H2S A;  4XEO A;  2EAY A;  1G51 A;  2I4N A;  2ZZG A;  3A7A A;  4RDX A;  4P75 C;  1NNH A;  2DEQ A;  2ART A;  3A32 A;  4P72 A;  4CH6 A;  3HXV A;  3HXW A;  3WQZ A;  4XTY A;  3RKX A;  3E9H A;  2P0L A;  1HTT A;  2ARS A;  1YFT A;  2CGH A;  3L1A A;  2CJ9 A;  2FYK A;  1PYS B;  4Q15 A;  1QF6 A;  4UPA A;  2DU7 A;  1WU7 A;  4P73 A;  4YPF A;  4E51 A;  3NEL A;  2I4O A;  1YFR A;  4G84 A;  2E65 A;  2AKW B;  3KFU A;  1JJC A;  3R07 A;  3A5Z A;  1YFS A;  2Q7H A;  3VQW A;  2DKG A;  4Q6G A;  4NCX A;  4YCU A;  3M4Q A;  1B70 A;  1USY A;  2QHV A;  3A5Y A;  3A74 A;  4XEM A;  2ZIM A;  4ZTZ B;  1BIA A;  3V7C A;  3UH0 A;  3QO7 A;  1EIY A;  4HWO A;  3L2Z A;  4OP0 A;  3BFM A;  3UGQ A;  2DZ9 A;  2ZR3 A;  4CS3 A;  1FYF A;  4PHC A;  4YRJ A;  3QO8 A;  3RKY A;  1ASZ A;  3HY1 A;  2ZNI A;  1NYR A;  1HXD A;  4H2W A;  4J15 A;  2DTO A;  3BJU A;  1EQR A;  11AS A;  5K1X A;  3TEG A;  1Z7M A;  4H02 A;  1SRY A;  4YRM A;  1EOV A;  1NYQ A;  1X2H A;  1SER A;  4H2X A;  4PG3 A;  4YDQ A;  4K88 A;  4HA8 A;  3HFV A;  1B7Y A;  4H2V A;  4YRQ A;  1VQZ A;  2ALY A;  2EJ9 A;  4DQ2 A;  2DQ3 A;  3V8L A;  3EFS A;  4P71 C;  4HWR A;  4XU1 A;  4RQF A;  2ZNJ A;  3PCO B;  4YRK A;  3RIR A;  4YRO A;  5E3I A;  1SES A;  3RL6 A;  4WF2 A;  4CH5 A;  4CS4 A;  1WYD A;  1X01 A;  2CJB A;  1RIQ A;  3PZC A;  4BW9 A;  4TVY A;  1ADY A;  3HFZ B;  1GGM A;  4YRG A;  4TWA A;  5ELO A;  4P72 C;  2DU5 A;  2DZC A;  2DXU A;  2C8M A;  3VQY A;  3VQV A;  4RQE A;  1X55 A;  1G5H A;  4YRP A;  5KNN A;  5HGQ A;  4P73 C;  2PME A;  2DXT A;  2IY5 A;  4YRC A;  4OLF A;  4O2D A;  3REX A;  2E5A A;  4ZIB A;  1L0W A;  1USY C;  3RGL A;  1IL2 A;  1BIB A;  3I7F A;  4XTU A;  2ZT6 A;  3MF1 A;  4YRR A;  1WPY A;  2Q5H A;  3A31 A;  1E1T A;  1EVK A;  3P8T A;  2AMC B;  1WQ7 A;  2DQ0 A;  1E24 A;  3RAC A;  4XTZ A;  2RHS B;  2DTH A;  3LC0 A;  5C52 B;  2EL9 A;  5F5W A;  1N9W A;  3QNE A;  4UP8 A;  3RF1 A;  4X5O A;  2Q7G A;  4P74 A;  1NJ2 A;  2E64 A;  3NEN A;  2DTI A;  4BWA A;  4HWT A;  2PMF A;  3TEH A;  4KR3 A;  3CMQ A;  3NET A;  3UGT A;  2Q7E A;  3A7R A;  3A7U A;  2E10 A;  3P8V A;  4CH4 A;  1LYL A;  1E22 A;  3ICA A;  1B8A A;  3HRK A;  4YCV A;  4XU0 A;  12AS A;  3PCO A;  1NJ1 A;  2I4M A;  4XTW A;  4XU3 A;  2J3M A;  4UP7 A;  2ODR D;  1BBU A;  2ZT7 A;  1B7Y B;  3HXX A;  1HC7 A;  1B76 A;  2ALY B;  4K86 A;  3HXU A;  1KMM A;  5ELN A;  4YYE A;  4TVA A;  4P3O A;  2C7I A;  2ZT8 A;  1H4Q A;  1NJ8 A;  4WJ3 M;  3MF2 A;  4EX5 A;  1ATI A;  1NJ5 A;  2G4C A;  2RHQ B;  4L87 A;  4TTV A;  4UP9 A;  2ZR2 A;  4HWS A;  4EO4 A;  2ZXF A;  2ZT5 A;  3FJP A;  3QO5 A;  1X54 A;  2I4L A;  1J5W A;  3DSQ A;  1H4V B; 
#chains in the Genus database with same CATH topology
 1WLE A;  1PYS A;  2XGT A;  3L4G B;  3V7S A;  2EJG A;  3HY0 A;  2AKW A;  4TVW A;  2QHT A;  3E9I A;  4TQD A;  1YGB A;  3V8K A;  2CJA A;  3P8Y A;  3OD1 A;  4RMF A;  4TQF A;  4P75 A;  3LSQ A;  4H2U A;  3HXY A;  3IAL A;  4DPG A;  2IY5 B;  2AMC A;  2ARU A;  1SET A;  4YRF A;  4YRI A;  4CS2 A;  3EFR A;  2RHS A;  4KR2 A;  4P3P A;  1ASY A;  3TUP A;  2ZZF A;  3QTC A;  4P74 C;  2ZIN A;  1X2G A;  3HXZ A;  3RUX A;  3LSS A;  4YRE A;  1JJC B;  4AH6 A;  4G85 A;  4H2Y A;  2ZCE A;  3HTZ A;  1B70 B;  3IG2 A;  5C53 B;  1E1O A;  3HRI A;  3NEM A;  4YRN A;  1G5I A;  5K1P A;  2P5I A;  1EIY B;  5C51 B;  3VQX A;  1KOG A;  4K87 A;  2ZIO A;  1EFW A;  2DVE A;  3REU A;  2E3C A;  4LNS A;  4WI1 A;  4YP0 A;  3RKW A;  2HNI A;  2EWN A;  3IKM B;  3G1Z A;  3M4P A;  4ZTU B;  3V8J A;  1W66 A;  1H4S A;  4XTV A;  4YRS A;  2ZZE A;  4LVL A;  4XTX A;  4YCW A;  2ZTG A;  3TEH B;  4H2X B;  2J3L A;  1Z7N A;  2QHU A;  3V7R A;  4H2T A;  3HFZ A;  1YB3 A;  2DJZ A;  2ODR C;  2CIM A;  1QE0 A;  2Q5I A;  3UFG A;  4P3N A;  2ZGW A;  4CH3 A;  2DDZ A;  2QHS A;  1ADJ A;  4KQE A;  1C0A A;  4HVC A;  4YRL A;  1WQW A;  2E41 A;  2RHQ A;  4HWP A;  2NS6 A;  3VBB A;  3IKL A;  2E1H A;  1H4T A;  4P71 A;  3W3S A;  1WNL A;  4LVM A;  3MEY A;  2XTI A;  4XU2 A;  1EVL A;  4YRT A;  1BBW A;  4TVA B;  4WJ4 A;  1NJ6 A;  1KMN A;  2EJF A;  3ERR A;  1X56 A;  3L4G A;  4H2S A;  4XEO A;  2EAY A;  1G51 A;  2I4N A;  2ZZG A;  3A7A A;  4RDX A;  4P75 C;  1NNH A;  2DEQ A;  2ART A;  3A32 A;  4P72 A;  4CH6 A;  3HXV A;  3HXW A;  3WQZ A;  4XTY A;  3RKX A;  3E9H A;  2P0L A;  1HTT A;  2ARS A;  1YFT A;  2CGH A;  3L1A A;  4LVJ A;  2CJ9 A;  2FYK A;  1PYS B;  4Q15 A;  1QF6 A;  4UPA A;  2DU7 A;  1WU7 A;  4P73 A;  4YPF A;  4E51 A;  3NEL A;  2I4O A;  1YFR A;  4G84 A;  2E65 A;  2AKW B;  3KFU A;  1JJC A;  3R07 A;  3A5Z A;  1YFS A;  2Q7H A;  3VQW A;  2DKG A;  4Q6G A;  4NCX A;  4YCU A;  3M4Q A;  1B70 A;  1USY A;  2QHV A;  3A5Y A;  3A74 A;  4XEM A;  2ZIM A;  4ZTZ B;  1BIA A;  3V7C A;  3UH0 A;  3QO7 A;  1EIY A;  4HWO A;  3L2Z A;  4OP0 A;  3BFM A;  3MQZ A;  3UGQ A;  2DZ9 A;  2ZR3 A;  4CS3 A;  1FYF A;  4PHC A;  4YRJ A;  3QO8 A;  3RKY A;  1ASZ A;  3HY1 A;  2ZNI A;  1NYR A;  1HXD A;  4H2W A;  4J15 A;  2DTO A;  3BJU A;  1EQR A;  11AS A;  5K1X A;  3TEG A;  1Z7M A;  4H02 A;  1SRY A;  4YRM A;  1EOV A;  1NYQ A;  1X2H A;  1SER A;  4H2X A;  4PG3 A;  4YDQ A;  4K88 A;  4HA8 A;  3HFV A;  1B7Y A;  4H2V A;  4YRQ A;  1VQZ A;  2ALY A;  2EJ9 A;  4DQ2 A;  2DQ3 A;  3V8L A;  4HT4 A;  3EFS A;  4P71 C;  4HWR A;  4XU1 A;  4RQF A;  2ZNJ A;  3PCO B;  4YRK A;  3RIR A;  4YRO A;  5E3I A;  1SES A;  3RL6 A;  4WF2 A;  4CH5 A;  4CS4 A;  1WYD A;  1X01 A;  2CJB A;  1RIQ A;  3PZC A;  4BW9 A;  4TVY A;  1ADY A;  3HFZ B;  1GGM A;  4YRG A;  4TWA A;  5ELO A;  4P72 C;  2DU5 A;  2DZC A;  2DXU A;  2C8M A;  3VQY A;  3VQV A;  4RQE A;  1X55 A;  1G5H A;  4YRP A;  5KNN A;  5HGQ A;  4LVI A;  4P73 C;  2PME A;  2DXT A;  2IY5 A;  4YRC A;  4OLF A;  4O2D A;  3REX A;  2E5A A;  4ZIB A;  1L0W A;  1USY C;  3RGL A;  1IL2 A;  1BIB A;  3I7F A;  4XTU A;  2ZT6 A;  3MF1 A;  4YRR A;  1WPY A;  2Q5H A;  4LVK A;  3A31 A;  1E1T A;  1EVK A;  3P8T A;  2AMC B;  1WQ7 A;  2DQ0 A;  1E24 A;  3RAC A;  4XTZ A;  2RHS B;  2DTH A;  3LC0 A;  5C52 B;  2EL9 A;  5F5W A;  1N9W A;  3QNE A;  4UP8 A;  3RF1 A;  4X5O A;  2Q7G A;  4P74 A;  1NJ2 A;  2A8E A;  2E64 A;  3NEN A;  2DTI A;  4BWA A;  4HWT A;  2PMF A;  3TEH A;  4KR3 A;  3CMQ A;  3NET A;  3UGT A;  2Q7E A;  3A7R A;  3A7U A;  2E10 A;  3P8V A;  4CH4 A;  1LYL A;  1E22 A;  3ICA A;  1B8A A;  3HRK A;  4YCV A;  4XU0 A;  12AS A;  3PCO A;  1NJ1 A;  2I4M A;  4XTW A;  4XU3 A;  2J3M A;  4UP7 A;  2ODR D;  1BBU A;  2ZT7 A;  1B7Y B;  3HXX A;  1HC7 A;  1B76 A;  2ALY B;  4K86 A;  3HXU A;  1KMM A;  5ELN A;  4YYE A;  4TVA A;  4P3O A;  2C7I A;  2ZT8 A;  1H4Q A;  1NJ8 A;  4WJ3 M;  3MF2 A;  4EX5 A;  1ATI A;  1NJ5 A;  2G4C A;  2RHQ B;  4L87 A;  4TTV A;  4UP9 A;  2ZR2 A;  4HWS A;  4EO4 A;  2ZXF A;  2ZT5 A;  3FJP A;  3QO5 A;  1X54 A;  2I4L A;  1J5W A;  3DSQ A;  1H4V B; 
#chains in the Genus database with same CATH homology
 1WLE A;  1PYS A;  2XGT A;  3L4G B;  3V7S A;  2EJG A;  3HY0 A;  2AKW A;  4TVW A;  2QHT A;  3E9I A;  4TQD A;  1YGB A;  3V8K A;  2CJA A;  3P8Y A;  3OD1 A;  4RMF A;  4TQF A;  4P75 A;  3LSQ A;  4H2U A;  3HXY A;  3IAL A;  4DPG A;  2IY5 B;  2AMC A;  2ARU A;  1SET A;  4YRF A;  4YRI A;  4CS2 A;  3EFR A;  2RHS A;  4KR2 A;  4P3P A;  1ASY A;  3TUP A;  2ZZF A;  3QTC A;  4P74 C;  2ZIN A;  1X2G A;  3HXZ A;  3RUX A;  3LSS A;  4YRE A;  1JJC B;  4AH6 A;  4G85 A;  4H2Y A;  2ZCE A;  3HTZ A;  1B70 B;  3IG2 A;  5C53 B;  1E1O A;  3HRI A;  3NEM A;  4YRN A;  1G5I A;  5K1P A;  2P5I A;  1EIY B;  5C51 B;  3VQX A;  1KOG A;  4K87 A;  2ZIO A;  1EFW A;  2DVE A;  3REU A;  2E3C A;  4LNS A;  4WI1 A;  4YP0 A;  3RKW A;  2HNI A;  2EWN A;  3IKM B;  3G1Z A;  3M4P A;  4ZTU B;  3V8J A;  1W66 A;  1H4S A;  4XTV A;  4YRS A;  2ZZE A;  4LVL A;  4XTX A;  4YCW A;  2ZTG A;  3TEH B;  4H2X B;  2J3L A;  1Z7N A;  2QHU A;  3V7R A;  4H2T A;  3HFZ A;  1YB3 A;  2DJZ A;  2ODR C;  2CIM A;  1QE0 A;  2Q5I A;  3UFG A;  4P3N A;  2ZGW A;  4CH3 A;  2DDZ A;  2QHS A;  1ADJ A;  4KQE A;  1C0A A;  4HVC A;  4YRL A;  1WQW A;  2E41 A;  2RHQ A;  4HWP A;  2NS6 A;  3VBB A;  3IKL A;  2E1H A;  1H4T A;  4P71 A;  3W3S A;  1WNL A;  4LVM A;  3MEY A;  2XTI A;  4XU2 A;  1EVL A;  4YRT A;  1BBW A;  4TVA B;  4WJ4 A;  1NJ6 A;  1KMN A;  2EJF A;  3ERR A;  1X56 A;  3L4G A;  4H2S A;  4XEO A;  2EAY A;  1G51 A;  2I4N A;  2ZZG A;  3A7A A;  4RDX A;  4P75 C;  1NNH A;  2DEQ A;  2ART A;  3A32 A;  4P72 A;  4CH6 A;  3HXV A;  3HXW A;  3WQZ A;  4XTY A;  3RKX A;  3E9H A;  2P0L A;  1HTT A;  2ARS A;  1YFT A;  2CGH A;  3L1A A;  4LVJ A;  2CJ9 A;  2FYK A;  1PYS B;  4Q15 A;  1QF6 A;  4UPA A;  2DU7 A;  1WU7 A;  4P73 A;  4YPF A;  4E51 A;  3NEL A;  2I4O A;  1YFR A;  4G84 A;  2E65 A;  2AKW B;  3KFU A;  1JJC A;  3R07 A;  3A5Z A;  1YFS A;  2Q7H A;  3VQW A;  2DKG A;  4Q6G A;  4NCX A;  4YCU A;  3M4Q A;  1B70 A;  1USY A;  2QHV A;  3A5Y A;  3A74 A;  4XEM A;  2ZIM A;  4ZTZ B;  1BIA A;  3V7C A;  3UH0 A;  3QO7 A;  1EIY A;  4HWO A;  3L2Z A;  4OP0 A;  3BFM A;  3MQZ A;  3UGQ A;  2DZ9 A;  2ZR3 A;  4CS3 A;  1FYF A;  4PHC A;  4YRJ A;  3QO8 A;  3RKY A;  1ASZ A;  3HY1 A;  2ZNI A;  1NYR A;  1HXD A;  4H2W A;  4J15 A;  2DTO A;  3BJU A;  1EQR A;  11AS A;  5K1X A;  3TEG A;  1Z7M A;  4H02 A;  1SRY A;  4YRM A;  1EOV A;  1NYQ A;  1X2H A;  1SER A;  4H2X A;  4PG3 A;  4YDQ A;  4K88 A;  4HA8 A;  3HFV A;  1B7Y A;  4H2V A;  4YRQ A;  1VQZ A;  2ALY A;  2EJ9 A;  4DQ2 A;  2DQ3 A;  3V8L A;  4HT4 A;  3EFS A;  4P71 C;  4HWR A;  4XU1 A;  4RQF A;  2ZNJ A;  3PCO B;  4YRK A;  3RIR A;  4YRO A;  5E3I A;  1SES A;  3RL6 A;  4WF2 A;  4CH5 A;  4CS4 A;  1WYD A;  1X01 A;  2CJB A;  1RIQ A;  3PZC A;  4BW9 A;  4TVY A;  1ADY A;  3HFZ B;  1GGM A;  4YRG A;  4TWA A;  5ELO A;  4P72 C;  2DU5 A;  2DZC A;  2DXU A;  2C8M A;  3VQY A;  3VQV A;  4RQE A;  1X55 A;  1G5H A;  4YRP A;  5KNN A;  5HGQ A;  4LVI A;  4P73 C;  2PME A;  2DXT A;  2IY5 A;  4YRC A;  4OLF A;  4O2D A;  3REX A;  2E5A A;  4ZIB A;  1L0W A;  1USY C;  3RGL A;  1IL2 A;  1BIB A;  3I7F A;  4XTU A;  2ZT6 A;  3MF1 A;  4YRR A;  1WPY A;  2Q5H A;  4LVK A;  3A31 A;  1E1T A;  1EVK A;  3P8T A;  2AMC B;  1WQ7 A;  2DQ0 A;  1E24 A;  3RAC A;  4XTZ A;  2RHS B;  2DTH A;  3LC0 A;  5C52 B;  2EL9 A;  5F5W A;  1N9W A;  3QNE A;  4UP8 A;  3RF1 A;  4X5O A;  2Q7G A;  4P74 A;  1NJ2 A;  2A8E A;  2E64 A;  3NEN A;  2DTI A;  4BWA A;  4HWT A;  2PMF A;  3TEH A;  4KR3 A;  3CMQ A;  3NET A;  3UGT A;  2Q7E A;  3A7R A;  3A7U A;  2E10 A;  3P8V A;  4CH4 A;  1LYL A;  1E22 A;  3ICA A;  1B8A A;  3HRK A;  4YCV A;  4XU0 A;  12AS A;  3PCO A;  1NJ1 A;  2I4M A;  4XTW A;  4XU3 A;  2J3M A;  4UP7 A;  2ODR D;  1BBU A;  2ZT7 A;  1B7Y B;  3HXX A;  1HC7 A;  1B76 A;  2ALY B;  4K86 A;  3HXU A;  1KMM A;  5ELN A;  4YYE A;  4TVA A;  4P3O A;  2C7I A;  2ZT8 A;  1H4Q A;  1NJ8 A;  4WJ3 M;  3MF2 A;  4EX5 A;  1ATI A;  1NJ5 A;  2G4C A;  2RHQ B;  4L87 A;  4TTV A;  4UP9 A;  2ZR2 A;  4HWS A;  4EO4 A;  2ZXF A;  2ZT5 A;  3FJP A;  3QO5 A;  1X54 A;  2I4L A;  1J5W A;  3DSQ A;  1H4V B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...