1E78 | Genus

Total Genus 204

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	204
sequence length	578
structure length	578
Chain Sequence	SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Time for openFile(/file/5cfb097a191f1c3b136c4f42/pdb.gz): 1164 ms

reading 578 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

578 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 36 ms

Adding embedded #jmolscript: select ({0:577});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Carrier protein
source organism	Homo sapiens
publication title	Binding of the General Anesthetics Propofol and Halothane to Human Serum Albumin. High Resolution Crystal Structures pubmed doi rcsb
molecule keywords	SERUM ALBUMIN
total genus	204
structure length	578
sequence length	578
chains with identical sequence	B
ec nomenclature
pdb deposition date	2000-08-25

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e78A03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e78A02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e78A04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e78A01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e78A06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e78A05

2BXHA 1GNJA 4N0UD 2BXLA 2I2ZA 3JRYA 4K2CA 5IJFA 4HGMB 1BKEA 2BXKA 2BXMA 1E7IA 4F5VA 1MA9A 4ZBRA 1HK4A 4EMXA 3LU8A 1E7CA 1HA2A 5GHKA 4E99A 3V03A 5FUOA 4F5SA 1UORA 4L9QA 5IIXA 4IW1A 1HK2A 4N0FD 1E7GA 4LUHA 3CX9A 5IFOA 1O9XA 5IJ5A 1HK1A 4IW2A 2BXFA 2BXQA 2XVUA 4PO0A 1E7AA 1LOTA 2BXDA 2XW1A 1GNIA 4LUFA 1J78A 1N5UA 3V09A 2BXOA 1BM0A 1HK3A 5IJEA 2BXPA 5IIUA 2XVVA 1BJ5A 4G03A 4OR0A 4F5UA 1KXPD 2BX8A 4L9KA 3TDLA 1H9ZA 2BXNA 1E7EA 4Z69A 4K71A 5DQFA 4G04A 2XSIA 2BXGA 2BXCA 4OT2A 4ZBQA 3LU7A 1HK5A 2BXEA 1E7FA 4HGKA 4J2VA 2XVQA 2VUEA 4F5TA 5ID9A 3JQZA 1KW2A 2VDBA 2XW0A 1E78A 3B9LA 3V08A 2BXBA 1E7HA 2I30A 4LB9A 2YDFA 3LU6A 4BKEA 3B9MA 5ID7A 2BXAA 3A73A 4L8UA 4JK4A 4LA0A 3UIVA 4S1YA 5HOZA 3SQJA 2BXIA 2XVWA 1AO6A 2VUFA 1TF0A 1J7EA 4LB2A 5IIHA 1E7BA 5DBYA
chains in the Genus database with same CATH superfamily

4ZUXV 3H37A 1MUHA 2BXHA 1GNJA 2LXTA 3WHSA 3ICXA 4N0UD 2BXLA 2I2ZA 3JRYA 3FWBC 4GDKB 4K2CA 5IJFA 4HGMB 1H5WA 3KJLA 3H3AA 1BKEA 1TXUA 2BXKA 2BXMA 4DM0A 1E7IA 3WHRA 4F5VA 2EFDA 1MA9A 2QHBA 4ZBRA 1MUSA 1IJGA 1HK4A 2GUTA 4FK5B 1JNBA 2NNWA 3LU8A 4ZCGA 4EMXA 3ECPA 1E7CA 1HA2A 1MIYA 5GHKA 4E99A 2QM6A 3V03A 3M99C 5FUOA 4F5SA 4FJCB 1UORA 4L9QA 5B5TA 2Z8JA 1SB0A 5IIXA 4IW1A 5GIPA 1HK2A 4N0FD 1E7GA 3NVMA 4LUHA 1KDXA 2QMCA 3CX9A 5IFOA 1O9XA 5IJ5A 3FWCC 1HK1A 4IW2A 2BXFA 2BXQA 2XVUA 5GIOA 5D7GA 4PO0A 1E7AA 1LOTA 2BXDA 2XW1A 2LQHA 1GNIA 4D7XA 4LUFA 1J78A 1N5UA 3V09A 2BXOA 1BM0A 1HK3A 2XMOA 5IJEA 4N3ZA 2BXPA 4W4UB 5IIUA 2K0NA 2XVVA 1BJ5A 2KBZA 4G03A 1LNSA 2AGHB 3WHQA 4OR0A 4F5UA 1KXPD 1FOUA 2BX8A 1NT2B 4L9KA 3VQIA 3TDLA 2OT3A 1H9ZA 2E0XA 2BXNA 1E7EA 2NQOA 3A75A 4Z69A 3SIUB 3KIKA 4K71A 2V36A 4TQ1A 2DG5A 4OTUA 4GDLB 5DQFA 4G04A 2XSIA 3NVIA 2BXGA 5BPKA 2JUHA 4G01A 2BXCA 4OT2A 4ZBQA 3MHSB 2DBXA 3LU7A 1HK5A 3PLAA 2EFEA 4TQ0A 2BXEA 1MIWA 1E7FA 3W1SA 2EFHA 4ZBKA 4HGKA 4M70B 4J2VA 2AJEA 2XVQA 2VUEA 4F5TA 4WA6B 4MBEC 4DHXB 5ID9A 1VZSA 3SIVB 3JQZA 3NVKA 1KW2A 3FNMA 2VDBA 2CKXA 2XW0A 3BPJA 1E78A 3B9LA 3V08A 2BXBA 2KWFA 1E7HA 3GA9L 2I30A 2EFCA 1E7BA 1MIVA 2Z8KA 2YDFA 3LU6A 4FIPB 4I9OA 4LB9A 4BY9C 4BKEA 2DYMA 3B9MA 5ID7A 2BXAA 4Z9OA 2ROHA 3A73A 4L8UA 4JK4A 4LA0A 2LQIA 4NAWB 3UIVA 1MM8A 2DBUA 4S1YA 2DYOA 2Z8IA 5HOZA 3SQJA 2BXIA 3NMUA 2E0YA 2LXSA 2XVWA 2LOQA 3MHHB 4C31B 1AO6A 2VUFA 2DBWA 3GQUA 4GDXA 3G9KD 3GQXA 1TF0A 1J7EA 4GG2A 4OTTA 2OZBB 5GINA 4LB2A 5IIHA 1VFIA 4ZC6A 5DBYA
chains in the Genus database with same CATH topology

4ZUXV 3H37A 2BXHA 1GNJA 3WHSA 3ICXA 4N0UD 2BXLA 2I2ZA 3JRYA 3FWBC 4GDKB 4K2CA 5IJFA 4HGMB 1H5WA 3KJLA 3H3AA 1BKEA 1TXUA 2BXKA 2BXMA 1E7IA 3WHRA 4F5VA 2EFDA 1MA9A 2QHBA 4ZBRA 1IJGA 1HK4A 4FK5B 1JNBA 2NNWA 3LU8A 4ZCGA 4EMXA 1E7CA 1HA2A 1MIYA 5GHKA 4E99A 2QM6A 3V03A 3M99C 5FUOA 4F5SA 4FJCB 1UORA 4L9QA 5B5TA 2Z8JA 5IIXA 4IW1A 5GIPA 1HK2A 4N0FD 1E7GA 3NVMA 4LUHA 2QMCA 3CX9A 5IFOA 1O9XA 5IJ5A 3FWCC 1HK1A 4IW2A 2BXFA 2BXQA 2XVUA 5GIOA 5D7GA 4PO0A 1E7AA 1LOTA 2BXDA 2XW1A 1GNIA 4LUFA 1J78A 1N5UA 3V09A 2BXOA 1BM0A 1HK3A 2XMOA 5IJEA 4N3ZA 2BXPA 4W4UB 5IIUA 2XVVA 1BJ5A 2KBZA 4G03A 1LNSA 3WHQA 4OR0A 4F5UA 1KXPD 1FOUA 2BX8A 1NT2B 4L9KA 3VQIA 3TDLA 2OT3A 1H9ZA 2E0XA 2BXNA 1E7EA 2NQOA 3A75A 4Z69A 3SIUB 3KIKA 4K71A 2V36A 4TQ1A 2DG5A 4OTUA 4GDLB 5DQFA 4G04A 2XSIA 3NVIA 2BXGA 5BPKA 2JUHA 4G01A 2BXCA 4OT2A 4ZBQA 3MHSB 2DBXA 3LU7A 1HK5A 3PLAA 2EFEA 4TQ0A 2BXEA 1MIWA 1E7FA 3W1SA 2EFHA 4ZBKA 4HGKA 4M70B 4J2VA 2AJEA 2XVQA 2VUEA 4F5TA 4WA6B 4MBEC 4DHXB 5ID9A 1VZSA 3SIVB 3JQZA 3NVKA 1KW2A 3FNMA 2VDBA 2CKXA 2XW0A 1E78A 3B9LA 3V08A 2BXBA 1E7HA 3GA9L 2I30A 2EFCA 1E7BA 1MIVA 2Z8KA 2YDFA 3LU6A 4FIPB 4LB9A 4BY9C 4BKEA 2DYMA 3B9MA 5ID7A 2BXAA 4Z9OA 2ROHA 3A73A 4L8UA 4JK4A 4LA0A 4NAWB 3UIVA 2DBUA 4S1YA 2DYOA 2Z8IA 5HOZA 3SQJA 2BXIA 3NMUA 2E0YA 2XVWA 4C31B 2LOQA 3MHHB 1AO6A 2VUFA 2DBWA 3GQUA 4GDXA 3G9KD 3GQXA 1TF0A 1J7EA 4GG2A 4OTTA 2OZBB 5GINA 4LB2A 5IIHA 1VFIA 4ZC6A 5DBYA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2BXH A;  1GNJ A;  4N0U D;  2BXL A;  2I2Z A;  3JRY A;  4K2C A;  5IJF A;  4HGM B;  1BKE A;  2BXK A;  2BXM A;  1E7I A;  4F5V A;  1MA9 A;  4ZBR A;  1HK4 A;  4EMX A;  3LU8 A;  1E7C A;  1HA2 A;  5GHK A;  4E99 A;  3V03 A;  5FUO A;  4F5S A;  1UOR A;  4L9Q A;  5IIX A;  4IW1 A;  1HK2 A;  4N0F D;  1E7G A;  4LUH A;  3CX9 A;  5IFO A;  1O9X A;  5IJ5 A;  1HK1 A;  4IW2 A;  2BXF A;  2BXQ A;  2XVU A;  4PO0 A;  1E7A A;  1LOT A;  2BXD A;  2XW1 A;  1GNI A;  4LUF A;  1J78 A;  1N5U A;  3V09 A;  2BXO A;  1BM0 A;  1HK3 A;  5IJE A;  2BXP A;  5IIU A;  2XVV A;  1BJ5 A;  4G03 A;  4OR0 A;  4F5U A;  1KXP D;  2BX8 A;  4L9K A;  3TDL A;  1H9Z A;  2BXN A;  1E7E A;  4Z69 A;  4K71 A;  5DQF A;  4G04 A;  2XSI A;  2BXG A;  2BXC A;  4OT2 A;  4ZBQ A;  3LU7 A;  1HK5 A;  2BXE A;  1E7F A;  4HGK A;  4J2V A;  2XVQ A;  2VUE A;  4F5T A;  5ID9 A;  3JQZ A;  1KW2 A;  2VDB A;  2XW0 A;  1E78 A;  3B9L A;  3V08 A;  2BXB A;  1E7H A;  2I30 A;  4LB9 A;  2YDF A;  3LU6 A;  4BKE A;  3B9M A;  5ID7 A;  2BXA A;  3A73 A;  4L8U A;  4JK4 A;  4LA0 A;  3UIV A;  4S1Y A;  5HOZ A;  3SQJ A;  2BXI A;  2XVW A;  1AO6 A;  2VUF A;  1TF0 A;  1J7E A;  4LB2 A;  5IIH A;  1E7B A;  5DBY A; 
#chains in the Genus database with same CATH topology
 4ZUX V;  3H37 A;  1MUH A;  2BXH A;  1GNJ A;  2LXT A;  3WHS A;  3ICX A;  4N0U D;  2BXL A;  2I2Z A;  3JRY A;  3FWB C;  4GDK B;  4K2C A;  5IJF A;  4HGM B;  1H5W A;  3KJL A;  3H3A A;  1BKE A;  1TXU A;  2BXK A;  2BXM A;  4DM0 A;  1E7I A;  3WHR A;  4F5V A;  2EFD A;  1MA9 A;  2QHB A;  4ZBR A;  1MUS A;  1IJG A;  1HK4 A;  2GUT A;  4FK5 B;  1JNB A;  2NNW A;  3LU8 A;  4ZCG A;  4EMX A;  3ECP A;  1E7C A;  1HA2 A;  1MIY A;  5GHK A;  4E99 A;  2QM6 A;  3V03 A;  3M99 C;  5FUO A;  4F5S A;  4FJC B;  1UOR A;  4L9Q A;  5B5T A;  2Z8J A;  1SB0 A;  5IIX A;  4IW1 A;  5GIP A;  1HK2 A;  4N0F D;  1E7G A;  3NVM A;  4LUH A;  1KDX A;  2QMC A;  3CX9 A;  5IFO A;  1O9X A;  5IJ5 A;  3FWC C;  1HK1 A;  4IW2 A;  2BXF A;  2BXQ A;  2XVU A;  5GIO A;  5D7G A;  4PO0 A;  1E7A A;  1LOT A;  2BXD A;  2XW1 A;  2LQH A;  1GNI A;  4D7X A;  4LUF A;  1J78 A;  1N5U A;  3V09 A;  2BXO A;  1BM0 A;  1HK3 A;  2XMO A;  5IJE A;  4N3Z A;  2BXP A;  4W4U B;  5IIU A;  2K0N A;  2XVV A;  1BJ5 A;  2KBZ A;  4G03 A;  1LNS A;  2AGH B;  3WHQ A;  4OR0 A;  4F5U A;  1KXP D;  1FOU A;  2BX8 A;  1NT2 B;  4L9K A;  3VQI A;  3TDL A;  2OT3 A;  1H9Z A;  2E0X A;  2BXN A;  1E7E A;  2NQO A;  3A75 A;  4Z69 A;  3SIU B;  3KIK A;  4K71 A;  2V36 A;  4TQ1 A;  2DG5 A;  4OTU A;  4GDL B;  5DQF A;  4G04 A;  2XSI A;  3NVI A;  2BXG A;  5BPK A;  2JUH A;  4G01 A;  2BXC A;  4OT2 A;  4ZBQ A;  3MHS B;  2DBX A;  3LU7 A;  1HK5 A;  3PLA A;  2EFE A;  4TQ0 A;  2BXE A;  1MIW A;  1E7F A;  3W1S A;  2EFH A;  4ZBK A;  4HGK A;  4M70 B;  4J2V A;  2AJE A;  2XVQ A;  2VUE A;  4F5T A;  4WA6 B;  4MBE C;  4DHX B;  5ID9 A;  1VZS A;  3SIV B;  3JQZ A;  3NVK A;  1KW2 A;  3FNM A;  2VDB A;  2CKX A;  2XW0 A;  3BPJ A;  1E78 A;  3B9L A;  3V08 A;  2BXB A;  2KWF A;  1E7H A;  3GA9 L;  2I30 A;  2EFC A;  1E7B A;  1MIV A;  2Z8K A;  2YDF A;  3LU6 A;  4FIP B;  4I9O A;  4LB9 A;  4BY9 C;  4BKE A;  2DYM A;  3B9M A;  5ID7 A;  2BXA A;  4Z9O A;  2ROH A;  3A73 A;  4L8U A;  4JK4 A;  4LA0 A;  2LQI A;  4NAW B;  3UIV A;  1MM8 A;  2DBU A;  4S1Y A;  2DYO A;  2Z8I A;  5HOZ A;  3SQJ A;  2BXI A;  3NMU A;  2E0Y A;  2LXS A;  2XVW A;  2LOQ A;  3MHH B;  4C31 B;  1AO6 A;  2VUF A;  2DBW A;  3GQU A;  4GDX A;  3G9K D;  3GQX A;  1TF0 A;  1J7E A;  4GG2 A;  4OTT A;  2OZB B;  5GIN A;  4LB2 A;  5IIH A;  1VFI A;  4ZC6 A;  5DBY A; 
#chains in the Genus database with same CATH homology
 4ZUX V;  3H37 A;  2BXH A;  1GNJ A;  3WHS A;  3ICX A;  4N0U D;  2BXL A;  2I2Z A;  3JRY A;  3FWB C;  4GDK B;  4K2C A;  5IJF A;  4HGM B;  1H5W A;  3KJL A;  3H3A A;  1BKE A;  1TXU A;  2BXK A;  2BXM A;  1E7I A;  3WHR A;  4F5V A;  2EFD A;  1MA9 A;  2QHB A;  4ZBR A;  1IJG A;  1HK4 A;  4FK5 B;  1JNB A;  2NNW A;  3LU8 A;  4ZCG A;  4EMX A;  1E7C A;  1HA2 A;  1MIY A;  5GHK A;  4E99 A;  2QM6 A;  3V03 A;  3M99 C;  5FUO A;  4F5S A;  4FJC B;  1UOR A;  4L9Q A;  5B5T A;  2Z8J A;  5IIX A;  4IW1 A;  5GIP A;  1HK2 A;  4N0F D;  1E7G A;  3NVM A;  4LUH A;  2QMC A;  3CX9 A;  5IFO A;  1O9X A;  5IJ5 A;  3FWC C;  1HK1 A;  4IW2 A;  2BXF A;  2BXQ A;  2XVU A;  5GIO A;  5D7G A;  4PO0 A;  1E7A A;  1LOT A;  2BXD A;  2XW1 A;  1GNI A;  4LUF A;  1J78 A;  1N5U A;  3V09 A;  2BXO A;  1BM0 A;  1HK3 A;  2XMO A;  5IJE A;  4N3Z A;  2BXP A;  4W4U B;  5IIU A;  2XVV A;  1BJ5 A;  2KBZ A;  4G03 A;  1LNS A;  3WHQ A;  4OR0 A;  4F5U A;  1KXP D;  1FOU A;  2BX8 A;  1NT2 B;  4L9K A;  3VQI A;  3TDL A;  2OT3 A;  1H9Z A;  2E0X A;  2BXN A;  1E7E A;  2NQO A;  3A75 A;  4Z69 A;  3SIU B;  3KIK A;  4K71 A;  2V36 A;  4TQ1 A;  2DG5 A;  4OTU A;  4GDL B;  5DQF A;  4G04 A;  2XSI A;  3NVI A;  2BXG A;  5BPK A;  2JUH A;  4G01 A;  2BXC A;  4OT2 A;  4ZBQ A;  3MHS B;  2DBX A;  3LU7 A;  1HK5 A;  3PLA A;  2EFE A;  4TQ0 A;  2BXE A;  1MIW A;  1E7F A;  3W1S A;  2EFH A;  4ZBK A;  4HGK A;  4M70 B;  4J2V A;  2AJE A;  2XVQ A;  2VUE A;  4F5T A;  4WA6 B;  4MBE C;  4DHX B;  5ID9 A;  1VZS A;  3SIV B;  3JQZ A;  3NVK A;  1KW2 A;  3FNM A;  2VDB A;  2CKX A;  2XW0 A;  1E78 A;  3B9L A;  3V08 A;  2BXB A;  1E7H A;  3GA9 L;  2I30 A;  2EFC A;  1E7B A;  1MIV A;  2Z8K A;  2YDF A;  3LU6 A;  4FIP B;  4LB9 A;  4BY9 C;  4BKE A;  2DYM A;  3B9M A;  5ID7 A;  2BXA A;  4Z9O A;  2ROH A;  3A73 A;  4L8U A;  4JK4 A;  4LA0 A;  4NAW B;  3UIV A;  2DBU A;  4S1Y A;  2DYO A;  2Z8I A;  5HOZ A;  3SQJ A;  2BXI A;  3NMU A;  2E0Y A;  2XVW A;  4C31 B;  2LOQ A;  3MHH B;  1AO6 A;  2VUF A;  2DBW A;  3GQU A;  4GDX A;  3G9K D;  3GQX A;  1TF0 A;  1J7E A;  4GG2 A;  4OTT A;  2OZB B;  5GIN A;  4LB2 A;  5IIH A;  1VFI A;  4ZC6 A;  5DBY A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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1E78A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations