4OT2A

Crystal structure of equine serum albumin in complex with naproxen
Total Genus 240
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
240
sequence length
580
structure length
580
Chain Sequence
KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGREDKEACFAEEGPKLVASSQLALA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serum albumin
publication title Structural studies of bovine, equine, and leporine serum albumin complexes with naproxen.
pubmed doi rcsb
molecule tags Transport protein
total genus 240
structure length 580
sequence length 580
ec nomenclature
pdb deposition date 2014-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4ot2A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4ot2A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4ot2A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4ot2A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4ot2A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4ot2A05
4PO0A 1BJ5A 1KW2A 4F5TA 1HA2A 4F5SA 2I30A 1O9XA 2VDBA 1J7EA 2I2ZA 4IW2A 2BXKA 3TDLA 1UORA 4E99A 2XSIA 2VUFA 4N0UD 1H9ZA 4G03A 3B9LA 1KXPD 1GNIA 3V08A 1BKEA 1GNJA 3V09A 5IJ5A 5IIHA 5IIUA 2XVUA 3JQZA 2BXEA 2BXIA 1HK5A 4LA0A 3A73A 4HGKA 4HGMB 2BXLA 4EMXA 1E7GA 2XVVA 3LU7A 4L9QA 4LUFA 2BXFA 1E7EA 1AO6A 5ID9A 1E78A 4IW1A 3UIVA 1E7HA 1TF0A 2BXOA 3LU6A 5IJEA 1E7AA 4K2CA 4LB2A 1E7BA 1MA9A 3SQJA 5DQFA 2BX8A 4LUHA 1BM0A 1HK4A 2BXPA 4ZBRA 1J78A 4OR0A 2VUEA 4N0FD 5HOZA 2BXHA 4F5UA 2BXCA 3B9MA 1N5UA 4S1YA 1E7IA 1HK2A 2BXNA 2YDFA 2BXAA 5FUOA 2BXMA 1HK1A 5IFOA 4L9KA 2BXQA 3V03A 1LOTA 4LB9A 2XW1A 1E7FA 4BKEA 2BXBA 4F5VA 2XW0A 5GHKA 4G04A 1HK3A 2XVQA 4J2VA 2BXDA 5DBYA 3JRYA 3CX9A 2BXGA 5ID7A 2XVWA 4ZBQA 4Z69A 4K71A 5IIXA 4OT2A 1E7CA 4JK4A 3LU8A 4L8UA 5IJFA
chains in the Genus database with same CATH superfamily
4PO0A 1BJ5A 1KW2A 4F5TA 2LXTA 4N3ZA 1HA2A 3WHSA 4F5SA 2I30A 1O9XA 2VDBA 1J7EA 2I2ZA 4IW2A 3SIUB 5GIOA 4MBEC 1NT2B 2BXKA 4I9OA 3M99C 5B5TA 4ZUXV 3TDLA 3FWCC 1UORA 2E0XA 2GUTA 4E99A 5BPKA 3ECPA 3PLAA 2XSIA 2VUFA 3KIKA 3NVKA 4N0UD 1H9ZA 1MIVA 2NNWA 2V36A 4G03A 4M70B 5GINA 2DBUA 3B9LA 3MHHB 2ROHA 1KXPD 4NAWB 4OTTA 1GNIA 3V08A 1MUSA 1BKEA 1GNJA 4Z9OA 3V09A 1FOUA 5IJ5A 3BPJA 5IIHA 5IIUA 2XVUA 3GA9L 3JQZA 2QHBA 1VZSA 4DHXB 2BXEA 2BXIA 1HK5A 1MIYA 4WA6B 2OZBB 4LA0A 3H37A 3A73A 4HGKA 4HGMB 3G9KD 2BXLA 4EMXA 1E7GA 1H5WA 2XVVA 2Z8KA 3GQXA 3LU7A 5GIPA 4TQ1A 4G01A 4L9QA 4LUFA 2BXFA 2LQIA 4FJCB 1E7EA 1AO6A 5ID9A 2AJEA 1KDXA 1E78A 2LQHA 3VQIA 1SB0A 2EFHA 2AGHB 4IW1A 3UIVA 3WHRA 1E7HA 1JNBA 1TF0A 2BXOA 2XMOA 3LU6A 1MM8A 3GQUA 4ZCGA 5IJEA 1E7AA 2DYMA 4GG2A 4BY9C 3NVIA 4K2CA 4LB2A 3ICXA 1E7BA 1MA9A 3SQJA 1LNSA 5D7GA 5DQFA 2BX8A 4GDLB 4LUHA 4FK5B 1BM0A 1HK4A 2BXPA 4ZBRA 1J78A 1TXUA 4OTUA 4OR0A 2VUEA 4N0FD 2Z8IA 5HOZA 2BXHA 4F5UA 2EFCA 2BXCA 2E0YA 2KWFA 2QM6A 1N5UA 3B9MA 4S1YA 1E7IA 2JUHA 2OT3A 1HK2A 2BXNA 2YDFA 2DYOA 2BXAA 4ZBKA 5FUOA 2BXMA 1HK1A 5IFOA 4C31B 4D7XA 2K0NA 3MHSB 4L9KA 2BXQA 3V03A 1LOTA 4LB9A 2DG5A 2XW1A 1E7FA 2Z8JA 4FIPB 4BKEA 2BXBA 2KBZA 2DBXA 4F5VA 2XW0A 3NMUA 3A75A 4W4UB 5GHKA 2EFDA 2NQOA 3FWBC 3H3AA 2EFEA 4G04A 4GDKB 4TQ0A 4GDXA 1HK3A 2XVQA 4J2VA 2BXDA 1MIWA 4ZC6A 5DBYA 1MUHA 3FNMA 3SIVB 2LOQA 3JRYA 2DBWA 2LXSA 3CX9A 2BXGA 5ID7A 2XVWA 1VFIA 2CKXA 4ZBQA 3WHQA 4Z69A 2QMCA 4K71A 5IIXA 4OT2A 1E7CA 4JK4A 4DM0A 3W1SA 3LU8A 4L8UA 3NVMA 1IJGA 3KJLA 5IJFA
chains in the Genus database with same CATH topology
4PO0A 1BJ5A 1KW2A 4F5TA 4N3ZA 1HA2A 3WHSA 4F5SA 2I30A 1O9XA 2VDBA 1J7EA 2I2ZA 4IW2A 3SIUB 5GIOA 4MBEC 1NT2B 2BXKA 3M99C 5B5TA 4ZUXV 3TDLA 3FWCC 1UORA 2E0XA 4E99A 5BPKA 3PLAA 2XSIA 2VUFA 3KIKA 3NVKA 4N0UD 1H9ZA 1MIVA 2NNWA 2V36A 4G03A 4M70B 5GINA 2DBUA 3B9LA 3MHHB 2ROHA 1KXPD 4NAWB 4OTTA 1GNIA 3V08A 1BKEA 1GNJA 4Z9OA 3V09A 1FOUA 5IJ5A 5IIHA 5IIUA 2XVUA 3GA9L 3JQZA 2QHBA 1VZSA 4DHXB 2BXEA 2BXIA 1HK5A 1MIYA 4WA6B 2OZBB 4LA0A 3H37A 3A73A 4HGKA 4HGMB 3G9KD 2BXLA 4EMXA 1E7GA 1H5WA 2XVVA 2Z8KA 3GQXA 3LU7A 5GIPA 4TQ1A 4G01A 4L9QA 4LUFA 2BXFA 4FJCB 1E7EA 1AO6A 5ID9A 2AJEA 1E78A 3VQIA 2EFHA 4IW1A 3UIVA 3WHRA 1E7HA 1JNBA 1TF0A 2BXOA 2XMOA 3LU6A 3GQUA 4ZCGA 5IJEA 1E7AA 2DYMA 4GG2A 4BY9C 3NVIA 4K2CA 4LB2A 3ICXA 1E7BA 1MA9A 3SQJA 1LNSA 5D7GA 5DQFA 2BX8A 4GDLB 4LUHA 4FK5B 1BM0A 1HK4A 2BXPA 4ZBRA 1J78A 1TXUA 4OTUA 4OR0A 2VUEA 4N0FD 2Z8IA 5HOZA 2BXHA 4F5UA 2EFCA 2BXCA 2E0YA 3B9MA 2QM6A 1N5UA 4S1YA 1E7IA 2JUHA 2OT3A 1HK2A 2BXNA 2YDFA 2DYOA 2BXAA 4ZBKA 5FUOA 2BXMA 1HK1A 5IFOA 4C31B 3MHSB 4L9KA 2BXQA 3V03A 1LOTA 4LB9A 2DG5A 2XW1A 1E7FA 2Z8JA 4FIPB 4BKEA 2BXBA 2KBZA 2DBXA 4F5VA 2XW0A 3NMUA 3A75A 4W4UB 5GHKA 2EFDA 2NQOA 3FWBC 3H3AA 2EFEA 4G04A 4GDKB 4TQ0A 4GDXA 1HK3A 2XVQA 4J2VA 2BXDA 1MIWA 4ZC6A 5DBYA 3FNMA 3SIVB 2LOQA 3JRYA 2DBWA 3CX9A 2BXGA 5ID7A 2XVWA 1VFIA 2CKXA 4ZBQA 3WHQA 4Z69A 2QMCA 4K71A 5IIXA 4OT2A 1E7CA 4JK4A 3W1SA 3LU8A 4L8UA 3NVMA 1IJGA 3KJLA 5IJFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PO0 A;  1BJ5 A;  1KW2 A;  4F5T A;  1HA2 A;  4F5S A;  2I30 A;  1O9X A;  2VDB A;  1J7E A;  2I2Z A;  4IW2 A;  2BXK A;  3TDL A;  1UOR A;  4E99 A;  2XSI A;  2VUF A;  4N0U D;  1H9Z A;  4G03 A;  3B9L A;  1KXP D;  1GNI A;  3V08 A;  1BKE A;  1GNJ A;  3V09 A;  5IJ5 A;  5IIH A;  5IIU A;  2XVU A;  3JQZ A;  2BXE A;  2BXI A;  1HK5 A;  4LA0 A;  3A73 A;  4HGK A;  4HGM B;  2BXL A;  4EMX A;  1E7G A;  2XVV A;  3LU7 A;  4L9Q A;  4LUF A;  2BXF A;  1E7E A;  1AO6 A;  5ID9 A;  1E78 A;  4IW1 A;  3UIV A;  1E7H A;  1TF0 A;  2BXO A;  3LU6 A;  5IJE A;  1E7A A;  4K2C A;  4LB2 A;  1E7B A;  1MA9 A;  3SQJ A;  5DQF A;  2BX8 A;  4LUH A;  1BM0 A;  1HK4 A;  2BXP A;  4ZBR A;  1J78 A;  4OR0 A;  2VUE A;  4N0F D;  5HOZ A;  2BXH A;  4F5U A;  2BXC A;  3B9M A;  1N5U A;  4S1Y A;  1E7I A;  1HK2 A;  2BXN A;  2YDF A;  2BXA A;  5FUO A;  2BXM A;  1HK1 A;  5IFO A;  4L9K A;  2BXQ A;  3V03 A;  1LOT A;  4LB9 A;  2XW1 A;  1E7F A;  4BKE A;  2BXB A;  4F5V A;  2XW0 A;  5GHK A;  4G04 A;  1HK3 A;  2XVQ A;  4J2V A;  2BXD A;  5DBY A;  3JRY A;  3CX9 A;  2BXG A;  5ID7 A;  2XVW A;  4ZBQ A;  4Z69 A;  4K71 A;  5IIX A;  4OT2 A;  1E7C A;  4JK4 A;  3LU8 A;  4L8U A;  5IJF A; 
#chains in the Genus database with same CATH topology
 4PO0 A;  1BJ5 A;  1KW2 A;  4F5T A;  2LXT A;  4N3Z A;  1HA2 A;  3WHS A;  4F5S A;  2I30 A;  1O9X A;  2VDB A;  1J7E A;  2I2Z A;  4IW2 A;  3SIU B;  5GIO A;  4MBE C;  1NT2 B;  2BXK A;  4I9O A;  3M99 C;  5B5T A;  4ZUX V;  3TDL A;  3FWC C;  1UOR A;  2E0X A;  2GUT A;  4E99 A;  5BPK A;  3ECP A;  3PLA A;  2XSI A;  2VUF A;  3KIK A;  3NVK A;  4N0U D;  1H9Z A;  1MIV A;  2NNW A;  2V36 A;  4G03 A;  4M70 B;  5GIN A;  2DBU A;  3B9L A;  3MHH B;  2ROH A;  1KXP D;  4NAW B;  4OTT A;  1GNI A;  3V08 A;  1MUS A;  1BKE A;  1GNJ A;  4Z9O A;  3V09 A;  1FOU A;  5IJ5 A;  3BPJ A;  5IIH A;  5IIU A;  2XVU A;  3GA9 L;  3JQZ A;  2QHB A;  1VZS A;  4DHX B;  2BXE A;  2BXI A;  1HK5 A;  1MIY A;  4WA6 B;  2OZB B;  4LA0 A;  3H37 A;  3A73 A;  4HGK A;  4HGM B;  3G9K D;  2BXL A;  4EMX A;  1E7G A;  1H5W A;  2XVV A;  2Z8K A;  3GQX A;  3LU7 A;  5GIP A;  4TQ1 A;  4G01 A;  4L9Q A;  4LUF A;  2BXF A;  2LQI A;  4FJC B;  1E7E A;  1AO6 A;  5ID9 A;  2AJE A;  1KDX A;  1E78 A;  2LQH A;  3VQI A;  1SB0 A;  2EFH A;  2AGH B;  4IW1 A;  3UIV A;  3WHR A;  1E7H A;  1JNB A;  1TF0 A;  2BXO A;  2XMO A;  3LU6 A;  1MM8 A;  3GQU A;  4ZCG A;  5IJE A;  1E7A A;  2DYM A;  4GG2 A;  4BY9 C;  3NVI A;  4K2C A;  4LB2 A;  3ICX A;  1E7B A;  1MA9 A;  3SQJ A;  1LNS A;  5D7G A;  5DQF A;  2BX8 A;  4GDL B;  4LUH A;  4FK5 B;  1BM0 A;  1HK4 A;  2BXP A;  4ZBR A;  1J78 A;  1TXU A;  4OTU A;  4OR0 A;  2VUE A;  4N0F D;  2Z8I A;  5HOZ A;  2BXH A;  4F5U A;  2EFC A;  2BXC A;  2E0Y A;  2KWF A;  2QM6 A;  1N5U A;  3B9M A;  4S1Y A;  1E7I A;  2JUH A;  2OT3 A;  1HK2 A;  2BXN A;  2YDF A;  2DYO A;  2BXA A;  4ZBK A;  5FUO A;  2BXM A;  1HK1 A;  5IFO A;  4C31 B;  4D7X A;  2K0N A;  3MHS B;  4L9K A;  2BXQ A;  3V03 A;  1LOT A;  4LB9 A;  2DG5 A;  2XW1 A;  1E7F A;  2Z8J A;  4FIP B;  4BKE A;  2BXB A;  2KBZ A;  2DBX A;  4F5V A;  2XW0 A;  3NMU A;  3A75 A;  4W4U B;  5GHK A;  2EFD A;  2NQO A;  3FWB C;  3H3A A;  2EFE A;  4G04 A;  4GDK B;  4TQ0 A;  4GDX A;  1HK3 A;  2XVQ A;  4J2V A;  2BXD A;  1MIW A;  4ZC6 A;  5DBY A;  1MUH A;  3FNM A;  3SIV B;  2LOQ A;  3JRY A;  2DBW A;  2LXS A;  3CX9 A;  2BXG A;  5ID7 A;  2XVW A;  1VFI A;  2CKX A;  4ZBQ A;  3WHQ A;  4Z69 A;  2QMC A;  4K71 A;  5IIX A;  4OT2 A;  1E7C A;  4JK4 A;  4DM0 A;  3W1S A;  3LU8 A;  4L8U A;  3NVM A;  1IJG A;  3KJL A;  5IJF A; 
#chains in the Genus database with same CATH homology
 4PO0 A;  1BJ5 A;  1KW2 A;  4F5T A;  4N3Z A;  1HA2 A;  3WHS A;  4F5S A;  2I30 A;  1O9X A;  2VDB A;  1J7E A;  2I2Z A;  4IW2 A;  3SIU B;  5GIO A;  4MBE C;  1NT2 B;  2BXK A;  3M99 C;  5B5T A;  4ZUX V;  3TDL A;  3FWC C;  1UOR A;  2E0X A;  4E99 A;  5BPK A;  3PLA A;  2XSI A;  2VUF A;  3KIK A;  3NVK A;  4N0U D;  1H9Z A;  1MIV A;  2NNW A;  2V36 A;  4G03 A;  4M70 B;  5GIN A;  2DBU A;  3B9L A;  3MHH B;  2ROH A;  1KXP D;  4NAW B;  4OTT A;  1GNI A;  3V08 A;  1BKE A;  1GNJ A;  4Z9O A;  3V09 A;  1FOU A;  5IJ5 A;  5IIH A;  5IIU A;  2XVU A;  3GA9 L;  3JQZ A;  2QHB A;  1VZS A;  4DHX B;  2BXE A;  2BXI A;  1HK5 A;  1MIY A;  4WA6 B;  2OZB B;  4LA0 A;  3H37 A;  3A73 A;  4HGK A;  4HGM B;  3G9K D;  2BXL A;  4EMX A;  1E7G A;  1H5W A;  2XVV A;  2Z8K A;  3GQX A;  3LU7 A;  5GIP A;  4TQ1 A;  4G01 A;  4L9Q A;  4LUF A;  2BXF A;  4FJC B;  1E7E A;  1AO6 A;  5ID9 A;  2AJE A;  1E78 A;  3VQI A;  2EFH A;  4IW1 A;  3UIV A;  3WHR A;  1E7H A;  1JNB A;  1TF0 A;  2BXO A;  2XMO A;  3LU6 A;  3GQU A;  4ZCG A;  5IJE A;  1E7A A;  2DYM A;  4GG2 A;  4BY9 C;  3NVI A;  4K2C A;  4LB2 A;  3ICX A;  1E7B A;  1MA9 A;  3SQJ A;  1LNS A;  5D7G A;  5DQF A;  2BX8 A;  4GDL B;  4LUH A;  4FK5 B;  1BM0 A;  1HK4 A;  2BXP A;  4ZBR A;  1J78 A;  1TXU A;  4OTU A;  4OR0 A;  2VUE A;  4N0F D;  2Z8I A;  5HOZ A;  2BXH A;  4F5U A;  2EFC A;  2BXC A;  2E0Y A;  3B9M A;  2QM6 A;  1N5U A;  4S1Y A;  1E7I A;  2JUH A;  2OT3 A;  1HK2 A;  2BXN A;  2YDF A;  2DYO A;  2BXA A;  4ZBK A;  5FUO A;  2BXM A;  1HK1 A;  5IFO A;  4C31 B;  3MHS B;  4L9K A;  2BXQ A;  3V03 A;  1LOT A;  4LB9 A;  2DG5 A;  2XW1 A;  1E7F A;  2Z8J A;  4FIP B;  4BKE A;  2BXB A;  2KBZ A;  2DBX A;  4F5V A;  2XW0 A;  3NMU A;  3A75 A;  4W4U B;  5GHK A;  2EFD A;  2NQO A;  3FWB C;  3H3A A;  2EFE A;  4G04 A;  4GDK B;  4TQ0 A;  4GDX A;  1HK3 A;  2XVQ A;  4J2V A;  2BXD A;  1MIW A;  4ZC6 A;  5DBY A;  3FNM A;  3SIV B;  2LOQ A;  3JRY A;  2DBW A;  3CX9 A;  2BXG A;  5ID7 A;  2XVW A;  1VFI A;  2CKX A;  4ZBQ A;  3WHQ A;  4Z69 A;  2QMC A;  4K71 A;  5IIX A;  4OT2 A;  1E7C A;  4JK4 A;  3W1S A;  3LU8 A;  4L8U A;  3NVM A;  1IJG A;  3KJL A;  5IJF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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