1MUHA

Crystal structure of tn5 transposase complexed with transposon end dna
Total Genus 159
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
159
sequence length
473
structure length
455
Chain Sequence
ALHRAADWAKSVFSSAALGDPRRTARLVNVAAQLAKYSGKSITISSEGSKAAQEGAYRFIRNPNVSAEAIRKAGAMQTVKLAQEFPELLAIEDTTSLSYRHQVAEELGKLGSIQDKSRGWWVHSVLLLEATTFRTVGLLHQEWWMRPDDPADADEKESGKWLAAAATSRLRMGSMMSNVIAVCDREADIHAYLQDKLAHNERFVVRSKHPRKDVESGLYLYDHLKNQPELGGYQISIPQKGVVDKRGKRKNRPARKASLSLRSGRITLKQGNITLNAVLAEEINPPKGETPLKWLLLTSEPVESLAQALRVIDIYTHRWRIEEFHKAWKTGAGAERQRMEEPDNLERMVSILSFVAVRLLQLRESFTPQSAETVLTPDECQLLGYLDKGKRKRKEKAGSLQWAYMAIARLGGFMDSKRTGIASWGALWEGWEALQSKLDGFLAAKDLMAQGIKIG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA TRANSFERRED STRAND
publication title Three-dimensional structure of the Tn5 synaptic complex transposition intermediate.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transcription/dna
total genus 159
structure length 455
sequence length 473
ec nomenclature
pdb deposition date 2002-09-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01609 DDE_Tnp_1 Transposase DDE domain
A PF02281 Dimer_Tnp_Tn5 Transposase Tn5 dimerisation domain
A PF14706 Tnp_DNA_bind Transposase DNA-binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.40 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Tn5 transposase; domain 1 1muhA01
1.10.740.10 Mainly Alpha Orthogonal Bundle Transferase Inhibitor Protein From Tn5; Chain A, domain2 Transferase Inhibitor Protein From Tn5; Chain 1muhA03
3.90.350.10 Alpha Beta Alpha-Beta Complex Transposase Inhibitor Protein From Tn5; Chain A, domain 1 Transposase Inhibitor Protein From Tn5; Chain A, domain 1 1muhA02
3ECPA 1B7EA 4DM0A 1MM8A 1MUHA 1MUSA
chains in the Genus database with same CATH superfamily
2QM6A 3H3AA 5HOZA 1GNJA 3WHQA 4DM0A 3LU7A 4L8UA 5FUOA 4OT2A 3MHSB 5IIHA 1O9XA 2NNWA 2BXGA 2EFHA 4LUHA 4W4UB 4LB9A 1NT2B 2XVQA 3V08A 3GQUA 4C31B 4FIPB 5D7GA 4BY9C 3ECPA 1HK3A 2BXEA 2ROHA 1J7EA 2E0XA 4LB2A 2OZBB 3A73A 1VFIA 1HK2A 2DYOA 4N3ZA 4N0UD 5DBYA 3UIVA 3ICXA 4LA0A 2BXHA 5IFOA 1TXUA 5IJFA 1TF0A 2VUFA 3JQZA 4F5SA 5IJEA 1SB0A 1H5WA 2QMCA 2KBZA 1LNSA 4TQ0A 2DBUA 4F5TA 3KIKA 4EMXA 4F5VA 2BXQA 1BKEA 2BXOA 4FJCB 1MA9A 1KW2A 1E78A 2XSIA 3JRYA 4PO0A 4ZUXV 1MUSA 2K0NA 4J2VA 2QHBA 2BXDA 2I30A 2AJEA 2LQIA 4G01A 2GUTA 5GIPA 4G03A 1JNBA 2E0YA 3LU8A 4ZC6A 4IW2A 1LOTA 4WA6B 1IJGA 5GIOA 4ZBKA 3KJLA 2XW1A 4OTUA 2DBWA 2Z8KA 2Z8JA 5IJ5A 4K2CA 2XW0A 3SIVB 2DG5A 3A75A 4GDKB 5GINA 5ID9A 1MIWA 2OT3A 2BXNA 2XVVA 3B9MA 1UORA 4L9QA 5BPKA 1MUHA 3FNMA 2EFDA 3CX9A 1AO6A 3NMUA 2DYMA 3GA9L 4TQ1A 4OTTA 3WHSA 3H37A 4G04A 3MHHB 4LUFA 2BXMA 3TDLA 1B7EA 2AGHB 3NVIA 3NVKA 4Z69A 1HK4A 2BXFA 1E7GA 2I2ZA 1KDXA 1VZSA 4M70B 3SIUB 2XVUA 1E7EA 2VDBA 3FWCC 4ZBRA 4IW1A 1BM0A 4ZCGA 4E99A 1FOUA 2BXAA 4MBEC 3SQJA 3BPJA 3FWBC 3LU6A 1HK5A 3NVMA 1HA2A 1E7HA 2BXLA 4HGMB 1KXPD 1J78A 2XVWA 1HK1A 2BXIA 4ZBQA 4F5UA 2BXCA 4D7XA 2BX8A 2JUHA 3V09A 2NQOA 2BXPA 1MIYA 5ID7A 4DHXB 1E7IA 2DBXA 2KWFA 2V36A 3G9KD 4S1YA 3B9LA 5IIUA 1E7AA 1E7CA 3PLAA 4GG2A 4NAWB 1E7BA 2BXBA 2EFCA 3GQXA 5DQFA 2BXKA 1MM8A 4FK5B 3WHRA 4N0FD 2LQHA 1BJ5A 4GDXA 1E7FA 4JK4A 2Z8IA 1GNIA 5B5TA 5IIXA 2EFEA 3M99C 3W1SA 4HGKA 2CKXA 2LXTA 4BKEA 3V03A 4K71A 3VQIA 4L9KA 4Z9OA 2XMOA 1H9ZA 2LXSA 2VUEA 2YDFA 5GHKA 2LOQA 4GDLB 4I9OA 1MIVA 1N5UA 4OR0A
chains in the Genus database with same CATH topology
3ECPA 1B7EA 4DM0A 1MM8A 1MUHA 1MUSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ECP A;  1B7E A;  4DM0 A;  1MM8 A;  1MUH A;  1MUS A; 
#chains in the Genus database with same CATH topology
 2QM6 A;  3H3A A;  5HOZ A;  1GNJ A;  3WHQ A;  4DM0 A;  3LU7 A;  4L8U A;  5FUO A;  4OT2 A;  3MHS B;  5IIH A;  1O9X A;  2NNW A;  2BXG A;  2EFH A;  4LUH A;  4W4U B;  4LB9 A;  1NT2 B;  2XVQ A;  3V08 A;  3GQU A;  4C31 B;  4FIP B;  5D7G A;  4BY9 C;  3ECP A;  1HK3 A;  2BXE A;  2ROH A;  1J7E A;  2E0X A;  4LB2 A;  2OZB B;  3A73 A;  1VFI A;  1HK2 A;  2DYO A;  4N3Z A;  4N0U D;  5DBY A;  3UIV A;  3ICX A;  4LA0 A;  2BXH A;  5IFO A;  1TXU A;  5IJF A;  1TF0 A;  2VUF A;  3JQZ A;  4F5S A;  5IJE A;  1SB0 A;  1H5W A;  2QMC A;  2KBZ A;  1LNS A;  4TQ0 A;  2DBU A;  4F5T A;  3KIK A;  4EMX A;  4F5V A;  2BXQ A;  1BKE A;  2BXO A;  4FJC B;  1MA9 A;  1KW2 A;  1E78 A;  2XSI A;  3JRY A;  4PO0 A;  4ZUX V;  1MUS A;  2K0N A;  4J2V A;  2QHB A;  2BXD A;  2I30 A;  2AJE A;  2LQI A;  4G01 A;  2GUT A;  5GIP A;  4G03 A;  1JNB A;  2E0Y A;  3LU8 A;  4ZC6 A;  4IW2 A;  1LOT A;  4WA6 B;  1IJG A;  5GIO A;  4ZBK A;  3KJL A;  2XW1 A;  4OTU A;  2DBW A;  2Z8K A;  2Z8J A;  5IJ5 A;  4K2C A;  2XW0 A;  3SIV B;  2DG5 A;  3A75 A;  4GDK B;  5GIN A;  5ID9 A;  1MIW A;  2OT3 A;  2BXN A;  2XVV A;  3B9M A;  1UOR A;  4L9Q A;  5BPK A;  1MUH A;  3FNM A;  2EFD A;  3CX9 A;  1AO6 A;  3NMU A;  2DYM A;  3GA9 L;  4TQ1 A;  4OTT A;  3WHS A;  3H37 A;  4G04 A;  3MHH B;  4LUF A;  2BXM A;  3TDL A;  1B7E A;  2AGH B;  3NVI A;  3NVK A;  4Z69 A;  1HK4 A;  2BXF A;  1E7G A;  2I2Z A;  1KDX A;  1VZS A;  4M70 B;  3SIU B;  2XVU A;  1E7E A;  2VDB A;  3FWC C;  4ZBR A;  4IW1 A;  1BM0 A;  4ZCG A;  4E99 A;  1FOU A;  2BXA A;  4MBE C;  3SQJ A;  3BPJ A;  3FWB C;  3LU6 A;  1HK5 A;  3NVM A;  1HA2 A;  1E7H A;  2BXL A;  4HGM B;  1KXP D;  1J78 A;  2XVW A;  1HK1 A;  2BXI A;  4ZBQ A;  4F5U A;  2BXC A;  4D7X A;  2BX8 A;  2JUH A;  3V09 A;  2NQO A;  2BXP A;  1MIY A;  5ID7 A;  4DHX B;  1E7I A;  2DBX A;  2KWF A;  2V36 A;  3G9K D;  4S1Y A;  3B9L A;  5IIU A;  1E7A A;  1E7C A;  3PLA A;  4GG2 A;  4NAW B;  1E7B A;  2BXB A;  2EFC A;  3GQX A;  5DQF A;  2BXK A;  1MM8 A;  4FK5 B;  3WHR A;  4N0F D;  2LQH A;  1BJ5 A;  4GDX A;  1E7F A;  4JK4 A;  2Z8I A;  1GNI A;  5B5T A;  5IIX A;  2EFE A;  3M99 C;  3W1S A;  4HGK A;  2CKX A;  2LXT A;  4BKE A;  3V03 A;  4K71 A;  3VQI A;  4L9K A;  4Z9O A;  2XMO A;  1H9Z A;  2LXS A;  2VUE A;  2YDF A;  5GHK A;  2LOQ A;  4GDL B;  4I9O A;  1MIV A;  1N5U A;  4OR0 A; 
#chains in the Genus database with same CATH homology
 3ECP A;  1B7E A;  4DM0 A;  1MM8 A;  1MUH A;  1MUS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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