2BXEA

Human serum albumin complexed with diflunisal
Total Genus 208
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
208
sequence length
578
structure length
569
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVAADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords SERUM ALBUMIN
publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 208
structure length 569
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxeA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxeA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxeA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxeA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxeA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxeA05
2YDFA 1HK2A 3V08A 4HGMB 1E7AA 2VUFA 1KXPD 4F5UA 5DQFA 4LUHA 5ID9A 3CX9A 4K2CA 2BXGA 4EMXA 3B9MA 3A73A 4HGKA 1E7EA 1HK3A 3JQZA 1H9ZA 1E7BA 4N0UD 1GNIA 4OT2A 5IIXA 2BXQA 4F5VA 3LU8A 2BXHA 4L9QA 2BXKA 4OR0A 1BKEA 2I2ZA 2XVWA 5DBYA 4ZBRA 5IJEA 4J2VA 1KW2A 4F5SA 4LUFA 1GNJA 2BXIA 2BXMA 4N0FD 1HK1A 1HK4A 1MA9A 2BXDA 4ZBQA 4JK4A 5IJFA 5IIHA 1E7CA 3UIVA 4LA0A 1J78A 1N5UA 3V09A 1E7IA 1BJ5A 2XW0A 3TDLA 3V03A 5IIUA 2I30A 2XVUA 4L8UA 4L9KA 2BXBA 1BM0A 4F5TA 4LB2A 5IJ5A 1LOTA 5HOZA 1E7HA 2VUEA 1E78A 2XVQA 4K71A 3JRYA 5ID7A 2BXLA 1E7GA 1UORA 2XSIA 3LU7A 4Z69A 2BXPA 4LB9A 2BXCA 2BXEA 5FUOA 4BKEA 5IFOA 3LU6A 1O9XA 2BXOA 5GHKA 2XVVA 4G04A 4E99A 2BXAA 4IW2A 1AO6A 2BX8A 1HA2A 4S1YA 2BXNA 3SQJA 4IW1A 1TF0A 2VDBA 1J7EA 1HK5A 2XW1A 2BXFA 3B9LA 4PO0A 4G03A 1E7FA
chains in the Genus database with same CATH superfamily
2YDFA 1HK2A 4M70B 4HGMB 3V08A 4GDLB 1E7AA 2VUFA 1KXPD 1MIWA 2DBXA 4F5UA 2LXTA 5DQFA 2V36A 4LUHA 2LQIA 5ID9A 4N3ZA 3CX9A 2KBZA 1JNBA 4K2CA 2Z8IA 2BXGA 3PLAA 4EMXA 3B9MA 2XMOA 2DYOA 3GQXA 4GDXA 3A73A 4HGKA 1E7EA 1HK3A 3JQZA 4OTUA 1H9ZA 2AGHB 1E7BA 3MHSB 4G01A 1LNSA 4MBEC 4N0UD 1GNIA 5GINA 4NAWB 4OT2A 5IIXA 2BXQA 4F5VA 2Z8KA 1MM8A 2DBWA 3WHQA 1MUSA 3NMUA 2DG5A 2EFHA 3LU8A 1KDXA 2BXHA 4L9QA 4W4UB 2AJEA 2BXKA 2E0XA 2JUHA 4OR0A 4TQ1A 2QHBA 1BKEA 2I2ZA 2NNWA 2OT3A 2XVWA 5DBYA 3KJLA 3SIVB 4ZBRA 4WA6B 5IJEA 1MIVA 1VFIA 2LXSA 4J2VA 1KW2A 4DHXB 5GIOA 2DYMA 4F5SA 3BPJA 4LUFA 1IJGA 1GNJA 2BXIA 2BXMA 3FNMA 4N0FD 1HK1A 4FK5B 4GG2A 4ZBKA 3NVKA 1HK4A 1MA9A 2BXDA 4ZBQA 4JK4A 5IJFA 5IIHA 1E7CA 3UIVA 2KWFA 4LA0A 4GDKB 3NVMA 2CKXA 1J78A 1N5UA 4ZC6A 3V09A 5GIPA 1E7IA 1BJ5A 1FOUA 2XW0A 4ZUXV 3TDLA 3V03A 5IIUA 2I30A 2XVUA 1VZSA 3H37A 4L8UA 4I9OA 4L9KA 2BXBA 1BM0A 5B5TA 4F5TA 3G9KD 5D7GA 4LB2A 5IJ5A 3FWBC 1LOTA 5HOZA 1E7HA 2VUEA 4OTTA 1NT2B 4DM0A 2NQOA 1E78A 2XVQA 3WHRA 3ICXA 2OZBB 4K71A 3JRYA 5ID7A 3W1SA 2BXLA 1E7GA 3VQIA 3SIUB 2K0NA 4C31B 3H3AA 1TXUA 3ECPA 3GA9L 1UORA 3M99C 4FIPB 2EFCA 2XSIA 3LU7A 3WHSA 4ZCGA 4Z69A 2BXPA 1MUHA 3MHHB 2GUTA 4TQ0A 4LB9A 2BXCA 2BXEA 5FUOA 4Z9OA 5IFOA 4BKEA 3LU6A 1O9XA 2EFDA 2Z8JA 2BXOA 5GHKA 1MIYA 3NVIA 2XVVA 4G04A 4E99A 1H5WA 2BXAA 2EFEA 2QM6A 4IW2A 1AO6A 2BX8A 2E0YA 1SB0A 3GQUA 1HA2A 4D7XA 2LOQA 4S1YA 2ROHA 5BPKA 2QMCA 2BXNA 3SQJA 4IW1A 1TF0A 2VDBA 1J7EA 1HK5A 2XW1A 3A75A 3FWCC 2BXFA 2DBUA 2LQHA 3B9LA 3KIKA 4FJCB 4PO0A 4G03A 4BY9C 1E7FA
chains in the Genus database with same CATH topology
2YDFA 1HK2A 4M70B 4HGMB 3V08A 4GDLB 1E7AA 2VUFA 1KXPD 1MIWA 2DBXA 4F5UA 5DQFA 2V36A 4LUHA 5ID9A 4N3ZA 3CX9A 2KBZA 1JNBA 4K2CA 2Z8IA 2BXGA 3PLAA 4EMXA 3B9MA 2XMOA 2DYOA 3GQXA 4GDXA 3A73A 4HGKA 1E7EA 1HK3A 3JQZA 4OTUA 1H9ZA 1E7BA 3MHSB 4G01A 1LNSA 4MBEC 4N0UD 1GNIA 5GINA 4NAWB 4OT2A 5IIXA 2BXQA 4F5VA 2Z8KA 2DBWA 3WHQA 3NMUA 2DG5A 2EFHA 3LU8A 2BXHA 4L9QA 4W4UB 2AJEA 2BXKA 2E0XA 2JUHA 4OR0A 4TQ1A 2QHBA 1BKEA 2I2ZA 2NNWA 2OT3A 2XVWA 5DBYA 3KJLA 3SIVB 4ZBRA 4WA6B 5IJEA 1MIVA 1VFIA 4J2VA 1KW2A 4DHXB 5GIOA 2DYMA 4F5SA 4LUFA 1IJGA 1GNJA 2BXIA 2BXMA 3FNMA 4N0FD 1HK1A 4FK5B 4GG2A 4ZBKA 3NVKA 1HK4A 1MA9A 2BXDA 4ZBQA 4JK4A 5IJFA 5IIHA 1E7CA 3UIVA 4LA0A 4GDKB 3NVMA 2CKXA 1J78A 1N5UA 4ZC6A 3V09A 5GIPA 1E7IA 1BJ5A 1FOUA 2XW0A 4ZUXV 3TDLA 3V03A 5IIUA 2I30A 2XVUA 1VZSA 3H37A 4L8UA 4L9KA 2BXBA 1BM0A 5B5TA 4F5TA 3G9KD 5D7GA 4LB2A 5IJ5A 3FWBC 1LOTA 5HOZA 1E7HA 2VUEA 4OTTA 1NT2B 2NQOA 1E78A 2XVQA 3WHRA 3ICXA 2OZBB 4K71A 3JRYA 5ID7A 3W1SA 2BXLA 1E7GA 3VQIA 3SIUB 4C31B 3H3AA 1TXUA 3GA9L 1UORA 3M99C 4FIPB 2EFCA 2XSIA 3LU7A 3WHSA 4ZCGA 4Z69A 2BXPA 3MHHB 4TQ0A 4LB9A 2BXCA 2BXEA 5FUOA 4Z9OA 5IFOA 4BKEA 3LU6A 1O9XA 2EFDA 2Z8JA 2BXOA 5GHKA 1MIYA 3NVIA 2XVVA 4G04A 4E99A 1H5WA 2BXAA 2EFEA 2QM6A 4IW2A 1AO6A 2BX8A 2E0YA 3GQUA 1HA2A 2LOQA 4S1YA 2ROHA 5BPKA 2QMCA 2BXNA 3SQJA 4IW1A 1TF0A 2VDBA 1J7EA 1HK5A 2XW1A 3A75A 3FWCC 2BXFA 2DBUA 3B9LA 3KIKA 4FJCB 4PO0A 4G03A 4BY9C 1E7FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YDF A;  1HK2 A;  3V08 A;  4HGM B;  1E7A A;  2VUF A;  1KXP D;  4F5U A;  5DQF A;  4LUH A;  5ID9 A;  3CX9 A;  4K2C A;  2BXG A;  4EMX A;  3B9M A;  3A73 A;  4HGK A;  1E7E A;  1HK3 A;  3JQZ A;  1H9Z A;  1E7B A;  4N0U D;  1GNI A;  4OT2 A;  5IIX A;  2BXQ A;  4F5V A;  3LU8 A;  2BXH A;  4L9Q A;  2BXK A;  4OR0 A;  1BKE A;  2I2Z A;  2XVW A;  5DBY A;  4ZBR A;  5IJE A;  4J2V A;  1KW2 A;  4F5S A;  4LUF A;  1GNJ A;  2BXI A;  2BXM A;  4N0F D;  1HK1 A;  1HK4 A;  1MA9 A;  2BXD A;  4ZBQ A;  4JK4 A;  5IJF A;  5IIH A;  1E7C A;  3UIV A;  4LA0 A;  1J78 A;  1N5U A;  3V09 A;  1E7I A;  1BJ5 A;  2XW0 A;  3TDL A;  3V03 A;  5IIU A;  2I30 A;  2XVU A;  4L8U A;  4L9K A;  2BXB A;  1BM0 A;  4F5T A;  4LB2 A;  5IJ5 A;  1LOT A;  5HOZ A;  1E7H A;  2VUE A;  1E78 A;  2XVQ A;  4K71 A;  3JRY A;  5ID7 A;  2BXL A;  1E7G A;  1UOR A;  2XSI A;  3LU7 A;  4Z69 A;  2BXP A;  4LB9 A;  2BXC A;  2BXE A;  5FUO A;  4BKE A;  5IFO A;  3LU6 A;  1O9X A;  2BXO A;  5GHK A;  2XVV A;  4G04 A;  4E99 A;  2BXA A;  4IW2 A;  1AO6 A;  2BX8 A;  1HA2 A;  4S1Y A;  2BXN A;  3SQJ A;  4IW1 A;  1TF0 A;  2VDB A;  1J7E A;  1HK5 A;  2XW1 A;  2BXF A;  3B9L A;  4PO0 A;  4G03 A;  1E7F A; 
#chains in the Genus database with same CATH topology
 2YDF A;  1HK2 A;  4M70 B;  4HGM B;  3V08 A;  4GDL B;  1E7A A;  2VUF A;  1KXP D;  1MIW A;  2DBX A;  4F5U A;  2LXT A;  5DQF A;  2V36 A;  4LUH A;  2LQI A;  5ID9 A;  4N3Z A;  3CX9 A;  2KBZ A;  1JNB A;  4K2C A;  2Z8I A;  2BXG A;  3PLA A;  4EMX A;  3B9M A;  2XMO A;  2DYO A;  3GQX A;  4GDX A;  3A73 A;  4HGK A;  1E7E A;  1HK3 A;  3JQZ A;  4OTU A;  1H9Z A;  2AGH B;  1E7B A;  3MHS B;  4G01 A;  1LNS A;  4MBE C;  4N0U D;  1GNI A;  5GIN A;  4NAW B;  4OT2 A;  5IIX A;  2BXQ A;  4F5V A;  2Z8K A;  1MM8 A;  2DBW A;  3WHQ A;  1MUS A;  3NMU A;  2DG5 A;  2EFH A;  3LU8 A;  1KDX A;  2BXH A;  4L9Q A;  4W4U B;  2AJE A;  2BXK A;  2E0X A;  2JUH A;  4OR0 A;  4TQ1 A;  2QHB A;  1BKE A;  2I2Z A;  2NNW A;  2OT3 A;  2XVW A;  5DBY A;  3KJL A;  3SIV B;  4ZBR A;  4WA6 B;  5IJE A;  1MIV A;  1VFI A;  2LXS A;  4J2V A;  1KW2 A;  4DHX B;  5GIO A;  2DYM A;  4F5S A;  3BPJ A;  4LUF A;  1IJG A;  1GNJ A;  2BXI A;  2BXM A;  3FNM A;  4N0F D;  1HK1 A;  4FK5 B;  4GG2 A;  4ZBK A;  3NVK A;  1HK4 A;  1MA9 A;  2BXD A;  4ZBQ A;  4JK4 A;  5IJF A;  5IIH A;  1E7C A;  3UIV A;  2KWF A;  4LA0 A;  4GDK B;  3NVM A;  2CKX A;  1J78 A;  1N5U A;  4ZC6 A;  3V09 A;  5GIP A;  1E7I A;  1BJ5 A;  1FOU A;  2XW0 A;  4ZUX V;  3TDL A;  3V03 A;  5IIU A;  2I30 A;  2XVU A;  1VZS A;  3H37 A;  4L8U A;  4I9O A;  4L9K A;  2BXB A;  1BM0 A;  5B5T A;  4F5T A;  3G9K D;  5D7G A;  4LB2 A;  5IJ5 A;  3FWB C;  1LOT A;  5HOZ A;  1E7H A;  2VUE A;  4OTT A;  1NT2 B;  4DM0 A;  2NQO A;  1E78 A;  2XVQ A;  3WHR A;  3ICX A;  2OZB B;  4K71 A;  3JRY A;  5ID7 A;  3W1S A;  2BXL A;  1E7G A;  3VQI A;  3SIU B;  2K0N A;  4C31 B;  3H3A A;  1TXU A;  3ECP A;  3GA9 L;  1UOR A;  3M99 C;  4FIP B;  2EFC A;  2XSI A;  3LU7 A;  3WHS A;  4ZCG A;  4Z69 A;  2BXP A;  1MUH A;  3MHH B;  2GUT A;  4TQ0 A;  4LB9 A;  2BXC A;  2BXE A;  5FUO A;  4Z9O A;  5IFO A;  4BKE A;  3LU6 A;  1O9X A;  2EFD A;  2Z8J A;  2BXO A;  5GHK A;  1MIY A;  3NVI A;  2XVV A;  4G04 A;  4E99 A;  1H5W A;  2BXA A;  2EFE A;  2QM6 A;  4IW2 A;  1AO6 A;  2BX8 A;  2E0Y A;  1SB0 A;  3GQU A;  1HA2 A;  4D7X A;  2LOQ A;  4S1Y A;  2ROH A;  5BPK A;  2QMC A;  2BXN A;  3SQJ A;  4IW1 A;  1TF0 A;  2VDB A;  1J7E A;  1HK5 A;  2XW1 A;  3A75 A;  3FWC C;  2BXF A;  2DBU A;  2LQH A;  3B9L A;  3KIK A;  4FJC B;  4PO0 A;  4G03 A;  4BY9 C;  1E7F A; 
#chains in the Genus database with same CATH homology
 2YDF A;  1HK2 A;  4M70 B;  4HGM B;  3V08 A;  4GDL B;  1E7A A;  2VUF A;  1KXP D;  1MIW A;  2DBX A;  4F5U A;  5DQF A;  2V36 A;  4LUH A;  5ID9 A;  4N3Z A;  3CX9 A;  2KBZ A;  1JNB A;  4K2C A;  2Z8I A;  2BXG A;  3PLA A;  4EMX A;  3B9M A;  2XMO A;  2DYO A;  3GQX A;  4GDX A;  3A73 A;  4HGK A;  1E7E A;  1HK3 A;  3JQZ A;  4OTU A;  1H9Z A;  1E7B A;  3MHS B;  4G01 A;  1LNS A;  4MBE C;  4N0U D;  1GNI A;  5GIN A;  4NAW B;  4OT2 A;  5IIX A;  2BXQ A;  4F5V A;  2Z8K A;  2DBW A;  3WHQ A;  3NMU A;  2DG5 A;  2EFH A;  3LU8 A;  2BXH A;  4L9Q A;  4W4U B;  2AJE A;  2BXK A;  2E0X A;  2JUH A;  4OR0 A;  4TQ1 A;  2QHB A;  1BKE A;  2I2Z A;  2NNW A;  2OT3 A;  2XVW A;  5DBY A;  3KJL A;  3SIV B;  4ZBR A;  4WA6 B;  5IJE A;  1MIV A;  1VFI A;  4J2V A;  1KW2 A;  4DHX B;  5GIO A;  2DYM A;  4F5S A;  4LUF A;  1IJG A;  1GNJ A;  2BXI A;  2BXM A;  3FNM A;  4N0F D;  1HK1 A;  4FK5 B;  4GG2 A;  4ZBK A;  3NVK A;  1HK4 A;  1MA9 A;  2BXD A;  4ZBQ A;  4JK4 A;  5IJF A;  5IIH A;  1E7C A;  3UIV A;  4LA0 A;  4GDK B;  3NVM A;  2CKX A;  1J78 A;  1N5U A;  4ZC6 A;  3V09 A;  5GIP A;  1E7I A;  1BJ5 A;  1FOU A;  2XW0 A;  4ZUX V;  3TDL A;  3V03 A;  5IIU A;  2I30 A;  2XVU A;  1VZS A;  3H37 A;  4L8U A;  4L9K A;  2BXB A;  1BM0 A;  5B5T A;  4F5T A;  3G9K D;  5D7G A;  4LB2 A;  5IJ5 A;  3FWB C;  1LOT A;  5HOZ A;  1E7H A;  2VUE A;  4OTT A;  1NT2 B;  2NQO A;  1E78 A;  2XVQ A;  3WHR A;  3ICX A;  2OZB B;  4K71 A;  3JRY A;  5ID7 A;  3W1S A;  2BXL A;  1E7G A;  3VQI A;  3SIU B;  4C31 B;  3H3A A;  1TXU A;  3GA9 L;  1UOR A;  3M99 C;  4FIP B;  2EFC A;  2XSI A;  3LU7 A;  3WHS A;  4ZCG A;  4Z69 A;  2BXP A;  3MHH B;  4TQ0 A;  4LB9 A;  2BXC A;  2BXE A;  5FUO A;  4Z9O A;  5IFO A;  4BKE A;  3LU6 A;  1O9X A;  2EFD A;  2Z8J A;  2BXO A;  5GHK A;  1MIY A;  3NVI A;  2XVV A;  4G04 A;  4E99 A;  1H5W A;  2BXA A;  2EFE A;  2QM6 A;  4IW2 A;  1AO6 A;  2BX8 A;  2E0Y A;  3GQU A;  1HA2 A;  2LOQ A;  4S1Y A;  2ROH A;  5BPK A;  2QMC A;  2BXN A;  3SQJ A;  4IW1 A;  1TF0 A;  2VDB A;  1J7E A;  1HK5 A;  2XW1 A;  3A75 A;  3FWC C;  2BXF A;  2DBU A;  3B9L A;  3KIK A;  4FJC B;  4PO0 A;  4G03 A;  4BY9 C;  1E7F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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