4G04A

High-resolution crystal structural variance analysis between recombinant and wild-type human serum albumin
Total Genus 217
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
217
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serum albumin
publication title High-resolution Crystal Structural Variance Analysis between Recombinant and Wild-type Human Serum Albumin
rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 217
structure length 578
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g04A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g04A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g04A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g04A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g04A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4g04A05
4F5UA 2XSIA 4JK4A 1BJ5A 1J78A 2XVQA 2BXQA 3LU7A 2BXDA 4LA0A 1E7IA 4K2CA 4HGMB 3B9MA 2XW0A 5DQFA 1HK4A 5IFOA 3LU6A 1HK1A 5HOZA 4L8UA 4N0UD 4G04A 4F5VA 1E7FA 1E7EA 1E7CA 1MA9A 4IW2A 5ID7A 1H9ZA 1BM0A 2BXKA 4Z69A 4OT2A 3V09A 2BXGA 4F5TA 4HGKA 4J2VA 4LB2A 2I30A 3V08A 1E7BA 1E7AA 2BXOA 1N5UA 4K71A 4S1YA 2BXAA 2BXFA 3LU8A 2XVUA 4L9QA 4LUFA 4ZBRA 1TF0A 4LUHA 4EMXA 4L9KA 4G03A 4LB9A 1HK2A 2BXNA 4PO0A 2BXBA 1E7GA 2VUEA 1E78A 1KXPD 3SQJA 5IJEA 3CX9A 1UORA 5IJFA 5DBYA 1KW2A 3JQZA 1O9XA 1HA2A 1LOTA 1BKEA 5IIHA 2BXHA 2VUFA 2BX8A 4IW1A 1AO6A 2XVWA 5FUOA 3A73A 4OR0A 2BXLA 4ZBQA 4BKEA 4F5SA 2BXCA 2XW1A 1HK5A 2BXEA 2BXMA 3UIVA 2VDBA 1J7EA 2BXIA 4N0FD 5IJ5A 5GHKA 3V03A 4E99A 5IIUA 3JRYA 2BXPA 3B9LA 1GNJA 2XVVA 2I2ZA 1E7HA 2YDFA 5ID9A 5IIXA 3TDLA 1HK3A 1GNIA
chains in the Genus database with same CATH superfamily
4F5UA 2XSIA 4JK4A 2GUTA 1TXUA 1BJ5A 1J78A 2XVQA 4WA6B 3NVKA 2BXQA 3LU7A 2V36A 1LNSA 2DBXA 2BXDA 2DYMA 4LA0A 1E7IA 4K2CA 4DM0A 4HGMB 4OTUA 4ZC6A 2E0YA 3GQXA 4M70B 1MIYA 2K0NA 3B9MA 4OTTA 2XW0A 1GNIA 4ZUXV 5DQFA 1HK4A 1IJGA 5IFOA 3LU6A 1HK1A 5HOZA 2LOQA 2NQOA 2OT3A 4N3ZA 3KJLA 4L8UA 3G9KD 4N0UD 2E0XA 3H3AA 4G04A 1E7FA 4F5VA 3SIVB 4FK5B 1E7EA 1E7CA 3GQUA 3W1SA 1MA9A 2XMOA 4IW2A 5B5TA 5D7GA 5ID7A 1MIVA 1H9ZA 1MM8A 2Z8JA 1H5WA 4GDKB 2JUHA 1BM0A 1KDXA 1FOUA 2BXKA 4MBEC 4Z69A 4OT2A 3V09A 2BXGA 4F5TA 3VQIA 4HGKA 4J2VA 4LB2A 2OZBB 4Z9OA 2I30A 3V08A 1VZSA 1E7BA 4DHXB 2EFDA 1E7AA 2BXOA 3NMUA 1N5UA 2QMCA 4K71A 4S1YA 2BXAA 2QM6A 2BXFA 3LU8A 2AGHB 2XVUA 4GDLB 2EFEA 4L9QA 4LUFA 4W4UB 4ZBKA 4ZBRA 3WHQA 4TQ0A 1TF0A 4LUHA 4EMXA 4L9KA 2NNWA 4G03A 4LB9A 3ECPA 1HK2A 2LQHA 2BXNA 5GINA 2DG5A 4ZCGA 4PO0A 2BXBA 4FJCB 1E7GA 2EFHA 2VUEA 1E78A 1KXPD 3SQJA 5IJEA 3CX9A 5GIOA 1UORA 2ROHA 4I9OA 4FIPB 5IJFA 3FNMA 3FWBC 5DBYA 1MIWA 1KW2A 3JQZA 3NVMA 1MUHA 3A75A 3WHRA 2EFCA 1MUSA 3SIUB 1O9XA 1HA2A 1LOTA 1BKEA 2Z8IA 2AJEA 2BXHA 4TQ1A 5IIHA 2KBZA 2VUFA 3WHSA 2BX8A 4IW1A 5BPKA 2Z8KA 3GA9L 1AO6A 1VFIA 2XVWA 5FUOA 4C31B 3NVIA 3A73A 4BY9C 4OR0A 2BXLA 4ZBQA 2LQIA 2DBWA 1NT2B 4BKEA 4D7XA 4F5SA 1JNBA 1SB0A 2DYOA 2LXSA 2BXCA 4GDXA 2XW1A 1HK5A 2BXEA 2BXMA 3UIVA 2QHBA 2VDBA 3BPJA 3PLAA 4GG2A 3MHSB 1J7EA 2BXIA 4N0FD 5IJ5A 5GHKA 3V03A 4E99A 3H37A 5IIUA 3FWCC 2CKXA 2LXTA 3JRYA 2KWFA 2BXPA 3B9LA 1GNJA 3ICXA 3M99C 2XVVA 5GIPA 4NAWB 2I2ZA 4G01A 1E7HA 3MHHB 2YDFA 5ID9A 5IIXA 3TDLA 1HK3A 2DBUA 3KIKA
chains in the Genus database with same CATH topology
4F5UA 2XSIA 4JK4A 1TXUA 1BJ5A 1J78A 2XVQA 4WA6B 3NVKA 2BXQA 3LU7A 2V36A 1LNSA 2DBXA 2BXDA 2DYMA 4LA0A 1E7IA 4K2CA 4HGMB 4OTUA 4ZC6A 2E0YA 3GQXA 4M70B 1MIYA 3B9MA 4OTTA 2XW0A 1GNIA 4ZUXV 5DQFA 1HK4A 1IJGA 5IFOA 3LU6A 1HK1A 5HOZA 2LOQA 2NQOA 2OT3A 4N3ZA 3KJLA 4L8UA 3G9KD 4N0UD 2E0XA 3H3AA 4G04A 1E7FA 4F5VA 3SIVB 4FK5B 1E7EA 1E7CA 3GQUA 3W1SA 1MA9A 2XMOA 4IW2A 5B5TA 5D7GA 5ID7A 1MIVA 1H9ZA 2Z8JA 1H5WA 4GDKB 2JUHA 1BM0A 1FOUA 2BXKA 4MBEC 4Z69A 4OT2A 3V09A 2BXGA 4F5TA 3VQIA 4HGKA 4J2VA 4LB2A 2OZBB 4Z9OA 2I30A 3V08A 1VZSA 1E7BA 4DHXB 2EFDA 1E7AA 2BXOA 3NMUA 1N5UA 2QMCA 4K71A 4S1YA 2BXAA 2QM6A 2BXFA 3LU8A 2XVUA 4GDLB 2EFEA 4L9QA 4LUFA 4W4UB 4ZBKA 4ZBRA 3WHQA 4TQ0A 1TF0A 4LUHA 4EMXA 4L9KA 2NNWA 4G03A 4LB9A 1HK2A 2BXNA 5GINA 2DG5A 4ZCGA 4PO0A 2BXBA 4FJCB 1E7GA 2EFHA 2VUEA 1E78A 1KXPD 3SQJA 5IJEA 3CX9A 5GIOA 1UORA 2ROHA 4FIPB 5IJFA 3FNMA 3FWBC 5DBYA 1MIWA 1KW2A 3JQZA 3NVMA 3A75A 3WHRA 2EFCA 3SIUB 1O9XA 1HA2A 1LOTA 1BKEA 2Z8IA 2AJEA 2BXHA 4TQ1A 5IIHA 2KBZA 2VUFA 3WHSA 2BX8A 4IW1A 5BPKA 2Z8KA 3GA9L 1AO6A 1VFIA 2XVWA 5FUOA 4C31B 3NVIA 3A73A 4BY9C 4OR0A 2BXLA 4ZBQA 4BKEA 2DBWA 1NT2B 4F5SA 1JNBA 2DYOA 2BXCA 4GDXA 2XW1A 1HK5A 2BXEA 2BXMA 3UIVA 2QHBA 2VDBA 3PLAA 4GG2A 3MHSB 1J7EA 2BXIA 4N0FD 5IJ5A 5GHKA 3V03A 4E99A 3H37A 5IIUA 3FWCC 2CKXA 3JRYA 2BXPA 3B9LA 1GNJA 3ICXA 3M99C 2XVVA 5GIPA 4NAWB 2I2ZA 4G01A 1E7HA 3MHHB 2YDFA 5ID9A 5IIXA 3TDLA 1HK3A 2DBUA 3KIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F5U A;  2XSI A;  4JK4 A;  1BJ5 A;  1J78 A;  2XVQ A;  2BXQ A;  3LU7 A;  2BXD A;  4LA0 A;  1E7I A;  4K2C A;  4HGM B;  3B9M A;  2XW0 A;  5DQF A;  1HK4 A;  5IFO A;  3LU6 A;  1HK1 A;  5HOZ A;  4L8U A;  4N0U D;  4G04 A;  4F5V A;  1E7F A;  1E7E A;  1E7C A;  1MA9 A;  4IW2 A;  5ID7 A;  1H9Z A;  1BM0 A;  2BXK A;  4Z69 A;  4OT2 A;  3V09 A;  2BXG A;  4F5T A;  4HGK A;  4J2V A;  4LB2 A;  2I30 A;  3V08 A;  1E7B A;  1E7A A;  2BXO A;  1N5U A;  4K71 A;  4S1Y A;  2BXA A;  2BXF A;  3LU8 A;  2XVU A;  4L9Q A;  4LUF A;  4ZBR A;  1TF0 A;  4LUH A;  4EMX A;  4L9K A;  4G03 A;  4LB9 A;  1HK2 A;  2BXN A;  4PO0 A;  2BXB A;  1E7G A;  2VUE A;  1E78 A;  1KXP D;  3SQJ A;  5IJE A;  3CX9 A;  1UOR A;  5IJF A;  5DBY A;  1KW2 A;  3JQZ A;  1O9X A;  1HA2 A;  1LOT A;  1BKE A;  5IIH A;  2BXH A;  2VUF A;  2BX8 A;  4IW1 A;  1AO6 A;  2XVW A;  5FUO A;  3A73 A;  4OR0 A;  2BXL A;  4ZBQ A;  4BKE A;  4F5S A;  2BXC A;  2XW1 A;  1HK5 A;  2BXE A;  2BXM A;  3UIV A;  2VDB A;  1J7E A;  2BXI A;  4N0F D;  5IJ5 A;  5GHK A;  3V03 A;  4E99 A;  5IIU A;  3JRY A;  2BXP A;  3B9L A;  1GNJ A;  2XVV A;  2I2Z A;  1E7H A;  2YDF A;  5ID9 A;  5IIX A;  3TDL A;  1HK3 A;  1GNI A; 
#chains in the Genus database with same CATH topology
 4F5U A;  2XSI A;  4JK4 A;  2GUT A;  1TXU A;  1BJ5 A;  1J78 A;  2XVQ A;  4WA6 B;  3NVK A;  2BXQ A;  3LU7 A;  2V36 A;  1LNS A;  2DBX A;  2BXD A;  2DYM A;  4LA0 A;  1E7I A;  4K2C A;  4DM0 A;  4HGM B;  4OTU A;  4ZC6 A;  2E0Y A;  3GQX A;  4M70 B;  1MIY A;  2K0N A;  3B9M A;  4OTT A;  2XW0 A;  1GNI A;  4ZUX V;  5DQF A;  1HK4 A;  1IJG A;  5IFO A;  3LU6 A;  1HK1 A;  5HOZ A;  2LOQ A;  2NQO A;  2OT3 A;  4N3Z A;  3KJL A;  4L8U A;  3G9K D;  4N0U D;  2E0X A;  3H3A A;  4G04 A;  1E7F A;  4F5V A;  3SIV B;  4FK5 B;  1E7E A;  1E7C A;  3GQU A;  3W1S A;  1MA9 A;  2XMO A;  4IW2 A;  5B5T A;  5D7G A;  5ID7 A;  1MIV A;  1H9Z A;  1MM8 A;  2Z8J A;  1H5W A;  4GDK B;  2JUH A;  1BM0 A;  1KDX A;  1FOU A;  2BXK A;  4MBE C;  4Z69 A;  4OT2 A;  3V09 A;  2BXG A;  4F5T A;  3VQI A;  4HGK A;  4J2V A;  4LB2 A;  2OZB B;  4Z9O A;  2I30 A;  3V08 A;  1VZS A;  1E7B A;  4DHX B;  2EFD A;  1E7A A;  2BXO A;  3NMU A;  1N5U A;  2QMC A;  4K71 A;  4S1Y A;  2BXA A;  2QM6 A;  2BXF A;  3LU8 A;  2AGH B;  2XVU A;  4GDL B;  2EFE A;  4L9Q A;  4LUF A;  4W4U B;  4ZBK A;  4ZBR A;  3WHQ A;  4TQ0 A;  1TF0 A;  4LUH A;  4EMX A;  4L9K A;  2NNW A;  4G03 A;  4LB9 A;  3ECP A;  1HK2 A;  2LQH A;  2BXN A;  5GIN A;  2DG5 A;  4ZCG A;  4PO0 A;  2BXB A;  4FJC B;  1E7G A;  2EFH A;  2VUE A;  1E78 A;  1KXP D;  3SQJ A;  5IJE A;  3CX9 A;  5GIO A;  1UOR A;  2ROH A;  4I9O A;  4FIP B;  5IJF A;  3FNM A;  3FWB C;  5DBY A;  1MIW A;  1KW2 A;  3JQZ A;  3NVM A;  1MUH A;  3A75 A;  3WHR A;  2EFC A;  1MUS A;  3SIU B;  1O9X A;  1HA2 A;  1LOT A;  1BKE A;  2Z8I A;  2AJE A;  2BXH A;  4TQ1 A;  5IIH A;  2KBZ A;  2VUF A;  3WHS A;  2BX8 A;  4IW1 A;  5BPK A;  2Z8K A;  3GA9 L;  1AO6 A;  1VFI A;  2XVW A;  5FUO A;  4C31 B;  3NVI A;  3A73 A;  4BY9 C;  4OR0 A;  2BXL A;  4ZBQ A;  2LQI A;  2DBW A;  1NT2 B;  4BKE A;  4D7X A;  4F5S A;  1JNB A;  1SB0 A;  2DYO A;  2LXS A;  2BXC A;  4GDX A;  2XW1 A;  1HK5 A;  2BXE A;  2BXM A;  3UIV A;  2QHB A;  2VDB A;  3BPJ A;  3PLA A;  4GG2 A;  3MHS B;  1J7E A;  2BXI A;  4N0F D;  5IJ5 A;  5GHK A;  3V03 A;  4E99 A;  3H37 A;  5IIU A;  3FWC C;  2CKX A;  2LXT A;  3JRY A;  2KWF A;  2BXP A;  3B9L A;  1GNJ A;  3ICX A;  3M99 C;  2XVV A;  5GIP A;  4NAW B;  2I2Z A;  4G01 A;  1E7H A;  3MHH B;  2YDF A;  5ID9 A;  5IIX A;  3TDL A;  1HK3 A;  2DBU A;  3KIK A; 
#chains in the Genus database with same CATH homology
 4F5U A;  2XSI A;  4JK4 A;  1TXU A;  1BJ5 A;  1J78 A;  2XVQ A;  4WA6 B;  3NVK A;  2BXQ A;  3LU7 A;  2V36 A;  1LNS A;  2DBX A;  2BXD A;  2DYM A;  4LA0 A;  1E7I A;  4K2C A;  4HGM B;  4OTU A;  4ZC6 A;  2E0Y A;  3GQX A;  4M70 B;  1MIY A;  3B9M A;  4OTT A;  2XW0 A;  1GNI A;  4ZUX V;  5DQF A;  1HK4 A;  1IJG A;  5IFO A;  3LU6 A;  1HK1 A;  5HOZ A;  2LOQ A;  2NQO A;  2OT3 A;  4N3Z A;  3KJL A;  4L8U A;  3G9K D;  4N0U D;  2E0X A;  3H3A A;  4G04 A;  1E7F A;  4F5V A;  3SIV B;  4FK5 B;  1E7E A;  1E7C A;  3GQU A;  3W1S A;  1MA9 A;  2XMO A;  4IW2 A;  5B5T A;  5D7G A;  5ID7 A;  1MIV A;  1H9Z A;  2Z8J A;  1H5W A;  4GDK B;  2JUH A;  1BM0 A;  1FOU A;  2BXK A;  4MBE C;  4Z69 A;  4OT2 A;  3V09 A;  2BXG A;  4F5T A;  3VQI A;  4HGK A;  4J2V A;  4LB2 A;  2OZB B;  4Z9O A;  2I30 A;  3V08 A;  1VZS A;  1E7B A;  4DHX B;  2EFD A;  1E7A A;  2BXO A;  3NMU A;  1N5U A;  2QMC A;  4K71 A;  4S1Y A;  2BXA A;  2QM6 A;  2BXF A;  3LU8 A;  2XVU A;  4GDL B;  2EFE A;  4L9Q A;  4LUF A;  4W4U B;  4ZBK A;  4ZBR A;  3WHQ A;  4TQ0 A;  1TF0 A;  4LUH A;  4EMX A;  4L9K A;  2NNW A;  4G03 A;  4LB9 A;  1HK2 A;  2BXN A;  5GIN A;  2DG5 A;  4ZCG A;  4PO0 A;  2BXB A;  4FJC B;  1E7G A;  2EFH A;  2VUE A;  1E78 A;  1KXP D;  3SQJ A;  5IJE A;  3CX9 A;  5GIO A;  1UOR A;  2ROH A;  4FIP B;  5IJF A;  3FNM A;  3FWB C;  5DBY A;  1MIW A;  1KW2 A;  3JQZ A;  3NVM A;  3A75 A;  3WHR A;  2EFC A;  3SIU B;  1O9X A;  1HA2 A;  1LOT A;  1BKE A;  2Z8I A;  2AJE A;  2BXH A;  4TQ1 A;  5IIH A;  2KBZ A;  2VUF A;  3WHS A;  2BX8 A;  4IW1 A;  5BPK A;  2Z8K A;  3GA9 L;  1AO6 A;  1VFI A;  2XVW A;  5FUO A;  4C31 B;  3NVI A;  3A73 A;  4BY9 C;  4OR0 A;  2BXL A;  4ZBQ A;  4BKE A;  2DBW A;  1NT2 B;  4F5S A;  1JNB A;  2DYO A;  2BXC A;  4GDX A;  2XW1 A;  1HK5 A;  2BXE A;  2BXM A;  3UIV A;  2QHB A;  2VDB A;  3PLA A;  4GG2 A;  3MHS B;  1J7E A;  2BXI A;  4N0F D;  5IJ5 A;  5GHK A;  3V03 A;  4E99 A;  3H37 A;  5IIU A;  3FWC C;  2CKX A;  3JRY A;  2BXP A;  3B9L A;  1GNJ A;  3ICX A;  3M99 C;  2XVV A;  5GIP A;  4NAW B;  2I2Z A;  4G01 A;  1E7H A;  3MHH B;  2YDF A;  5ID9 A;  5IIX A;  3TDL A;  1HK3 A;  2DBU A;  3KIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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