2BXDA

Human serum albumin complexed with warfarin
Total Genus 214
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
214
sequence length
578
structure length
578
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords SERUM ALBUMIN
publication title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 214
structure length 578
sequence length 578
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxdA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxdA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxdA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxdA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxdA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 2bxdA05
4LB2A 5ID7A 1BJ5A 4HGMB 4PO0A 1E7BA 1HK5A 2XVVA 2VUEA 4N0FD 2BXPA 3JQZA 2BXDA 4IW1A 1GNIA 2BXCA 4L8UA 3V08A 1E7CA 4LA0A 3LU6A 1O9XA 2BXGA 4Z69A 1BM0A 2BXOA 4F5UA 2YDFA 2BXAA 1HA2A 1E7EA 4N0UD 1HK2A 3LU7A 1UORA 2I2ZA 3A73A 4K2CA 3SQJA 3TDLA 2XVUA 4BKEA 1J78A 4JK4A 1HK3A 1N5UA 2XVWA 4G04A 4LUFA 2BXFA 5IFOA 2XSIA 5HOZA 1E78A 2BXHA 1AO6A 2VUFA 2I30A 5IIHA 4J2VA 5IJEA 2BXIA 2XW1A 4LUHA 5ID9A 1E7GA 2BXBA 3V09A 1BKEA 1H9ZA 4ZBRA 4F5SA 4S1YA 4L9QA 4K71A 3UIVA 1LOTA 4F5TA 3V03A 2BXQA 4HGKA 1E7AA 4G03A 2BXKA 4OR0A 3JRYA 4L9KA 5IJ5A 2XVQA 3B9LA 4OT2A 5GHKA 5IIXA 2BX8A 4LB9A 1HK4A 2BXLA 4F5VA 5FUOA 1MA9A 5DQFA 1KW2A 2BXEA 5DBYA 2VDBA 2BXNA 4ZBQA 1TF0A 1GNJA 1E7IA 5IIUA 5IJFA 3CX9A 4E99A 1E7FA 1KXPD 1HK1A 4IW2A 4EMXA 1J7EA 3LU8A 3B9MA 1E7HA 2XW0A 2BXMA
chains in the Genus database with same CATH superfamily
2DYOA 4DHXB 4LB2A 5ID7A 3A75A 2LQIA 2E0XA 3MHSB 2EFEA 1BJ5A 4HGMB 2DG5A 4PO0A 5BPKA 4GDKB 1E7BA 4GG2A 1HK5A 2XVVA 2VUEA 4BY9C 3M99C 4N0FD 4NAWB 2BXPA 1MIVA 3JQZA 2BXDA 3H3AA 1H5WA 3H37A 4IW1A 1GNIA 3NVIA 2BXCA 4L8UA 3V08A 1E7CA 4LA0A 2QM6A 1MM8A 3KIKA 4OTTA 3GA9L 1O9XA 2BXGA 3LU6A 1KDXA 4N3ZA 4Z69A 4ZBKA 1BM0A 2BXOA 1SB0A 3BPJA 4F5UA 2YDFA 2BXAA 1JNBA 3MHHB 4I9OA 1HA2A 2OZBB 5GIOA 1E7EA 3NVMA 4G01A 4N0UD 1HK2A 2EFCA 3LU7A 4ZUXV 1UORA 2I2ZA 3A73A 2EFHA 4C31B 5D7GA 4K2CA 3SQJA 3WHQA 3TDLA 4GDXA 2XVUA 3GQXA 4BKEA 1J78A 2GUTA 2OT3A 1HK3A 1N5UA 4JK4A 2XVWA 4G04A 4LUFA 4GDLB 2CKXA 2DBXA 1MIYA 2BXFA 3ECPA 4Z9OA 2QHBA 5IFOA 1IJGA 2JUHA 2AGHB 2XSIA 1E78A 2BXHA 5HOZA 1AO6A 2VUFA 1LNSA 2I30A 5IIHA 4J2VA 2DBWA 5IJEA 2K0NA 4D7XA 4ZCGA 2BXIA 2LOQA 2XW1A 2DYMA 2Z8KA 4LUHA 2EFDA 1E7GA 3ICXA 5ID9A 5GIPA 2BXBA 2V36A 3SIVB 4FK5B 3V09A 1VFIA 1BKEA 1H9ZA 4ZBRA 4F5SA 1MUHA 2AJEA 4S1YA 4L9QA 2KWFA 4FIPB 4K71A 3UIVA 1TXUA 1LOTA 1FOUA 3FWCC 4FJCB 2Z8IA 3FWBC 5GINA 4DM0A 4F5TA 3V03A 2BXQA 4HGKA 1E7AA 4TQ1A 2DBUA 4TQ0A 4G03A 3KJLA 2E0YA 2BXKA 2NNWA 4OR0A 3JRYA 2LXTA 4L9KA 2XMOA 5IJ5A 3FNMA 3PLAA 3WHRA 2XVQA 3B9LA 3VQIA 2KBZA 4OT2A 5GHKA 2BX8A 5IIXA 3W1SA 4LB9A 3GQUA 2NQOA 3WHSA 1HK4A 4MBEC 2LQHA 2BXLA 4F5VA 5FUOA 1VZSA 1MA9A 1NT2B 5DQFA 1KW2A 2BXEA 5DBYA 2VDBA 2Z8JA 1MUSA 3SIUB 2BXNA 4ZBQA 2ROHA 4W4UB 4WA6B 4OTUA 2QMCA 3NMUA 5B5TA 1TF0A 1GNJA 1E7IA 5IIUA 3NVKA 5IJFA 3CX9A 4M70B 4E99A 1E7FA 1KXPD 1HK1A 4IW2A 4EMXA 1MIWA 2LXSA 4ZC6A 1J7EA 3LU8A 3G9KD 3B9MA 1E7HA 2XW0A 2BXMA
chains in the Genus database with same CATH topology
2DYOA 4DHXB 4LB2A 5ID7A 3A75A 2E0XA 3MHSB 2EFEA 1BJ5A 4HGMB 2DG5A 4PO0A 5BPKA 4GDKB 1E7BA 4GG2A 1HK5A 2XVVA 2VUEA 4BY9C 3M99C 4N0FD 4NAWB 2BXPA 1MIVA 3JQZA 2BXDA 3H3AA 1H5WA 3H37A 4IW1A 1GNIA 3NVIA 2BXCA 4L8UA 3V08A 1E7CA 4LA0A 2QM6A 3KIKA 4OTTA 3GA9L 1O9XA 2BXGA 3LU6A 4N3ZA 4Z69A 4ZBKA 1BM0A 2BXOA 4F5UA 2YDFA 2BXAA 1JNBA 3MHHB 1HA2A 2OZBB 5GIOA 1E7EA 3NVMA 4G01A 4N0UD 1HK2A 2EFCA 3LU7A 4ZUXV 1UORA 2I2ZA 3A73A 2EFHA 4C31B 5D7GA 4K2CA 3SQJA 3WHQA 3TDLA 4GDXA 2XVUA 3GQXA 4BKEA 1J78A 2OT3A 4JK4A 1HK3A 1N5UA 2XVWA 4G04A 4LUFA 4GDLB 2CKXA 2DBXA 1MIYA 2BXFA 4Z9OA 2QHBA 5IFOA 1IJGA 2JUHA 2XSIA 5HOZA 1E78A 2BXHA 1AO6A 2VUFA 1LNSA 2I30A 5IIHA 4J2VA 2DBWA 5IJEA 4ZCGA 2BXIA 2LOQA 2XW1A 2DYMA 2Z8KA 4LUHA 2EFDA 1E7GA 3ICXA 5ID9A 5GIPA 2BXBA 2V36A 3SIVB 4FK5B 3V09A 1VFIA 1BKEA 1H9ZA 4ZBRA 4F5SA 2AJEA 4S1YA 4L9QA 4FIPB 4K71A 3UIVA 1TXUA 1LOTA 1FOUA 3FWCC 4FJCB 2Z8IA 3FWBC 5GINA 4F5TA 3V03A 2BXQA 4HGKA 1E7AA 4TQ1A 2DBUA 4TQ0A 4G03A 3KJLA 2E0YA 2BXKA 2NNWA 4OR0A 3JRYA 4L9KA 2XMOA 5IJ5A 3FNMA 3PLAA 3WHRA 2XVQA 3B9LA 3VQIA 2KBZA 4OT2A 5GHKA 2BX8A 5IIXA 3W1SA 4LB9A 3GQUA 2NQOA 3WHSA 1HK4A 4MBEC 2BXLA 4F5VA 5FUOA 1VZSA 1MA9A 1NT2B 5DQFA 1KW2A 2BXEA 5DBYA 2VDBA 2Z8JA 3SIUB 2BXNA 4ZBQA 2ROHA 4W4UB 4WA6B 4OTUA 2QMCA 3NMUA 5B5TA 1TF0A 1GNJA 1E7IA 5IIUA 3NVKA 5IJFA 3CX9A 4M70B 4E99A 1E7FA 1KXPD 1HK1A 4IW2A 4EMXA 1MIWA 4ZC6A 1J7EA 3LU8A 3G9KD 3B9MA 1E7HA 2XW0A 2BXMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LB2 A;  5ID7 A;  1BJ5 A;  4HGM B;  4PO0 A;  1E7B A;  1HK5 A;  2XVV A;  2VUE A;  4N0F D;  2BXP A;  3JQZ A;  2BXD A;  4IW1 A;  1GNI A;  2BXC A;  4L8U A;  3V08 A;  1E7C A;  4LA0 A;  3LU6 A;  1O9X A;  2BXG A;  4Z69 A;  1BM0 A;  2BXO A;  4F5U A;  2YDF A;  2BXA A;  1HA2 A;  1E7E A;  4N0U D;  1HK2 A;  3LU7 A;  1UOR A;  2I2Z A;  3A73 A;  4K2C A;  3SQJ A;  3TDL A;  2XVU A;  4BKE A;  1J78 A;  4JK4 A;  1HK3 A;  1N5U A;  2XVW A;  4G04 A;  4LUF A;  2BXF A;  5IFO A;  2XSI A;  5HOZ A;  1E78 A;  2BXH A;  1AO6 A;  2VUF A;  2I30 A;  5IIH A;  4J2V A;  5IJE A;  2BXI A;  2XW1 A;  4LUH A;  5ID9 A;  1E7G A;  2BXB A;  3V09 A;  1BKE A;  1H9Z A;  4ZBR A;  4F5S A;  4S1Y A;  4L9Q A;  4K71 A;  3UIV A;  1LOT A;  4F5T A;  3V03 A;  2BXQ A;  4HGK A;  1E7A A;  4G03 A;  2BXK A;  4OR0 A;  3JRY A;  4L9K A;  5IJ5 A;  2XVQ A;  3B9L A;  4OT2 A;  5GHK A;  5IIX A;  2BX8 A;  4LB9 A;  1HK4 A;  2BXL A;  4F5V A;  5FUO A;  1MA9 A;  5DQF A;  1KW2 A;  2BXE A;  5DBY A;  2VDB A;  2BXN A;  4ZBQ A;  1TF0 A;  1GNJ A;  1E7I A;  5IIU A;  5IJF A;  3CX9 A;  4E99 A;  1E7F A;  1KXP D;  1HK1 A;  4IW2 A;  4EMX A;  1J7E A;  3LU8 A;  3B9M A;  1E7H A;  2XW0 A;  2BXM A; 
#chains in the Genus database with same CATH topology
 2DYO A;  4DHX B;  4LB2 A;  5ID7 A;  3A75 A;  2LQI A;  2E0X A;  3MHS B;  2EFE A;  1BJ5 A;  4HGM B;  2DG5 A;  4PO0 A;  5BPK A;  4GDK B;  1E7B A;  4GG2 A;  1HK5 A;  2XVV A;  2VUE A;  4BY9 C;  3M99 C;  4N0F D;  4NAW B;  2BXP A;  1MIV A;  3JQZ A;  2BXD A;  3H3A A;  1H5W A;  3H37 A;  4IW1 A;  1GNI A;  3NVI A;  2BXC A;  4L8U A;  3V08 A;  1E7C A;  4LA0 A;  2QM6 A;  1MM8 A;  3KIK A;  4OTT A;  3GA9 L;  1O9X A;  2BXG A;  3LU6 A;  1KDX A;  4N3Z A;  4Z69 A;  4ZBK A;  1BM0 A;  2BXO A;  1SB0 A;  3BPJ A;  4F5U A;  2YDF A;  2BXA A;  1JNB A;  3MHH B;  4I9O A;  1HA2 A;  2OZB B;  5GIO A;  1E7E A;  3NVM A;  4G01 A;  4N0U D;  1HK2 A;  2EFC A;  3LU7 A;  4ZUX V;  1UOR A;  2I2Z A;  3A73 A;  2EFH A;  4C31 B;  5D7G A;  4K2C A;  3SQJ A;  3WHQ A;  3TDL A;  4GDX A;  2XVU A;  3GQX A;  4BKE A;  1J78 A;  2GUT A;  2OT3 A;  1HK3 A;  1N5U A;  4JK4 A;  2XVW A;  4G04 A;  4LUF A;  4GDL B;  2CKX A;  2DBX A;  1MIY A;  2BXF A;  3ECP A;  4Z9O A;  2QHB A;  5IFO A;  1IJG A;  2JUH A;  2AGH B;  2XSI A;  1E78 A;  2BXH A;  5HOZ A;  1AO6 A;  2VUF A;  1LNS A;  2I30 A;  5IIH A;  4J2V A;  2DBW A;  5IJE A;  2K0N A;  4D7X A;  4ZCG A;  2BXI A;  2LOQ A;  2XW1 A;  2DYM A;  2Z8K A;  4LUH A;  2EFD A;  1E7G A;  3ICX A;  5ID9 A;  5GIP A;  2BXB A;  2V36 A;  3SIV B;  4FK5 B;  3V09 A;  1VFI A;  1BKE A;  1H9Z A;  4ZBR A;  4F5S A;  1MUH A;  2AJE A;  4S1Y A;  4L9Q A;  2KWF A;  4FIP B;  4K71 A;  3UIV A;  1TXU A;  1LOT A;  1FOU A;  3FWC C;  4FJC B;  2Z8I A;  3FWB C;  5GIN A;  4DM0 A;  4F5T A;  3V03 A;  2BXQ A;  4HGK A;  1E7A A;  4TQ1 A;  2DBU A;  4TQ0 A;  4G03 A;  3KJL A;  2E0Y A;  2BXK A;  2NNW A;  4OR0 A;  3JRY A;  2LXT A;  4L9K A;  2XMO A;  5IJ5 A;  3FNM A;  3PLA A;  3WHR A;  2XVQ A;  3B9L A;  3VQI A;  2KBZ A;  4OT2 A;  5GHK A;  2BX8 A;  5IIX A;  3W1S A;  4LB9 A;  3GQU A;  2NQO A;  3WHS A;  1HK4 A;  4MBE C;  2LQH A;  2BXL A;  4F5V A;  5FUO A;  1VZS A;  1MA9 A;  1NT2 B;  5DQF A;  1KW2 A;  2BXE A;  5DBY A;  2VDB A;  2Z8J A;  1MUS A;  3SIU B;  2BXN A;  4ZBQ A;  2ROH A;  4W4U B;  4WA6 B;  4OTU A;  2QMC A;  3NMU A;  5B5T A;  1TF0 A;  1GNJ A;  1E7I A;  5IIU A;  3NVK A;  5IJF A;  3CX9 A;  4M70 B;  4E99 A;  1E7F A;  1KXP D;  1HK1 A;  4IW2 A;  4EMX A;  1MIW A;  2LXS A;  4ZC6 A;  1J7E A;  3LU8 A;  3G9K D;  3B9M A;  1E7H A;  2XW0 A;  2BXM A; 
#chains in the Genus database with same CATH homology
 2DYO A;  4DHX B;  4LB2 A;  5ID7 A;  3A75 A;  2E0X A;  3MHS B;  2EFE A;  1BJ5 A;  4HGM B;  2DG5 A;  4PO0 A;  5BPK A;  4GDK B;  1E7B A;  4GG2 A;  1HK5 A;  2XVV A;  2VUE A;  4BY9 C;  3M99 C;  4N0F D;  4NAW B;  2BXP A;  1MIV A;  3JQZ A;  2BXD A;  3H3A A;  1H5W A;  3H37 A;  4IW1 A;  1GNI A;  3NVI A;  2BXC A;  4L8U A;  3V08 A;  1E7C A;  4LA0 A;  2QM6 A;  3KIK A;  4OTT A;  3GA9 L;  1O9X A;  2BXG A;  3LU6 A;  4N3Z A;  4Z69 A;  4ZBK A;  1BM0 A;  2BXO A;  4F5U A;  2YDF A;  2BXA A;  1JNB A;  3MHH B;  1HA2 A;  2OZB B;  5GIO A;  1E7E A;  3NVM A;  4G01 A;  4N0U D;  1HK2 A;  2EFC A;  3LU7 A;  4ZUX V;  1UOR A;  2I2Z A;  3A73 A;  2EFH A;  4C31 B;  5D7G A;  4K2C A;  3SQJ A;  3WHQ A;  3TDL A;  4GDX A;  2XVU A;  3GQX A;  4BKE A;  1J78 A;  2OT3 A;  4JK4 A;  1HK3 A;  1N5U A;  2XVW A;  4G04 A;  4LUF A;  4GDL B;  2CKX A;  2DBX A;  1MIY A;  2BXF A;  4Z9O A;  2QHB A;  5IFO A;  1IJG A;  2JUH A;  2XSI A;  5HOZ A;  1E78 A;  2BXH A;  1AO6 A;  2VUF A;  1LNS A;  2I30 A;  5IIH A;  4J2V A;  2DBW A;  5IJE A;  4ZCG A;  2BXI A;  2LOQ A;  2XW1 A;  2DYM A;  2Z8K A;  4LUH A;  2EFD A;  1E7G A;  3ICX A;  5ID9 A;  5GIP A;  2BXB A;  2V36 A;  3SIV B;  4FK5 B;  3V09 A;  1VFI A;  1BKE A;  1H9Z A;  4ZBR A;  4F5S A;  2AJE A;  4S1Y A;  4L9Q A;  4FIP B;  4K71 A;  3UIV A;  1TXU A;  1LOT A;  1FOU A;  3FWC C;  4FJC B;  2Z8I A;  3FWB C;  5GIN A;  4F5T A;  3V03 A;  2BXQ A;  4HGK A;  1E7A A;  4TQ1 A;  2DBU A;  4TQ0 A;  4G03 A;  3KJL A;  2E0Y A;  2BXK A;  2NNW A;  4OR0 A;  3JRY A;  4L9K A;  2XMO A;  5IJ5 A;  3FNM A;  3PLA A;  3WHR A;  2XVQ A;  3B9L A;  3VQI A;  2KBZ A;  4OT2 A;  5GHK A;  2BX8 A;  5IIX A;  3W1S A;  4LB9 A;  3GQU A;  2NQO A;  3WHS A;  1HK4 A;  4MBE C;  2BXL A;  4F5V A;  5FUO A;  1VZS A;  1MA9 A;  1NT2 B;  5DQF A;  1KW2 A;  2BXE A;  5DBY A;  2VDB A;  2Z8J A;  3SIU B;  2BXN A;  4ZBQ A;  2ROH A;  4W4U B;  4WA6 B;  4OTU A;  2QMC A;  3NMU A;  5B5T A;  1TF0 A;  1GNJ A;  1E7I A;  5IIU A;  3NVK A;  5IJF A;  3CX9 A;  4M70 B;  4E99 A;  1E7F A;  1KXP D;  1HK1 A;  4IW2 A;  4EMX A;  1MIW A;  4ZC6 A;  1J7E A;  3LU8 A;  3G9K D;  3B9M A;  1E7H A;  2XW0 A;  2BXM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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