1KW2A

Crystal structure of uncomplexed vitamin d-binding protein
Total Genus 175
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
455
structure length
455
Chain Sequence
GRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPKELAKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNIL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Vitamin D-binding protein
publication title Crystal structures of the vitamin D-binding protein and its complex with actin: structural basis of the actin-scavenger system.
pubmed doi rcsb
molecule tags Transport protein
total genus 175
structure length 455
sequence length 455
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
A PF09164 VitD-bind_III Vitamin D binding protein, domain III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1kw2A05
2I30A 2BXEA 1H9ZA 2VDBA 3JQZA 4G04A 4L9QA 4L8UA 4PO0A 5IJEA 3V09A 4L9KA 2BXMA 5DQFA 2I2ZA 3UIVA 1HK2A 2BX8A 1KW2A 2XW0A 5IIUA 2XVQA 1BM0A 4HGMB 4IW1A 5DBYA 1E7CA 3CX9A 3V03A 2BXQA 1HK5A 1AO6A 1LOTA 1E7FA 2BXHA 4ZBRA 4IW2A 5IJ5A 5HOZA 2BXAA 1KXPD 4F5TA 1J7EA 2XW1A 1E7BA 1E7AA 5ID7A 2XVVA 1E7HA 2BXCA 3V08A 4E99A 1E7GA 5IFOA 4F5VA 4LUFA 4LB2A 2XVUA 3B9LA 4Z69A 4ZBQA 1J78A 4BKEA 1HK4A 4F5UA 3A73A 3LU6A 4OT2A 2XVWA 3TDLA 5IIXA 1BKEA 5ID9A 4OR0A 1E78A 1UORA 4LUHA 2BXFA 2BXPA 2BXNA 2BXIA 5GHKA 3B9MA 2XSIA 2YDFA 2BXBA 2BXDA 4K2CA 5IJFA 1N5UA 1E7EA 4N0UD 1BJ5A 2BXOA 3LU7A 4LB9A 4K71A 4JK4A 4G03A 5IIHA 2VUEA 4N0FD 2VUFA 4EMXA 3SQJA 4HGKA 1E7IA 4J2VA 4LA0A 1HK1A 1GNJA 1HA2A 1MA9A 1TF0A 5FUOA 2BXKA 4F5SA 1GNIA 1O9XA 2BXLA 3LU8A 1HK3A 3JRYA 4S1YA 2BXGA
chains in the Genus database with same CATH superfamily
2E0XA 2I30A 2BXEA 2NQOA 1H9ZA 4FIPB 2VDBA 3JQZA 4G04A 3KJLA 4L9QA 4L8UA 4Z9OA 4ZCGA 4PO0A 1H5WA 5IJEA 3V09A 2QM6A 2BXMA 4L9KA 3VQIA 5DQFA 2V36A 3PLAA 3NVMA 2I2ZA 3UIVA 5BPKA 4BY9C 1HK2A 2BX8A 1VFIA 2QMCA 2EFHA 2ROHA 1KW2A 2XW0A 5IIUA 1IJGA 4N3ZA 2QHBA 2XVQA 1MUSA 1BM0A 3BPJA 3FWCC 2NNWA 4HGMB 3GQUA 3MHHB 4IW1A 5DBYA 1E7CA 4OTUA 2Z8IA 4ZBKA 3NVIA 4GG2A 4M70B 3CX9A 2DYOA 3V03A 2DBUA 2AGHB 2BXQA 4TQ1A 1HK5A 1AO6A 1LOTA 5GIPA 4DM0A 3NVKA 1E7FA 4GDXA 2BXHA 4ZBRA 4IW2A 1FOUA 5IJ5A 3WHRA 3M99C 5HOZA 3GA9L 2BXAA 5B5TA 1KXPD 2AJEA 4F5TA 1JNBA 4ZC6A 1J7EA 1TXUA 2XW1A 1E7BA 1E7AA 2LOQA 2EFEA 5ID7A 2XVVA 3FWBC 5GIOA 1E7HA 2BXCA 4GDKB 3V08A 3KIKA 2LXSA 4E99A 1E7GA 2LXTA 5IFOA 4LUFA 4DHXB 4LB2A 4F5VA 2XVUA 2JUHA 1MIWA 1KDXA 3B9LA 4Z69A 3GQXA 4ZBQA 1J78A 2EFCA 4BKEA 1HK4A 2LQIA 4F5UA 2Z8KA 2DYMA 3A73A 2KWFA 3LU6A 1SB0A 2XVWA 4OT2A 3TDLA 5IIXA 2OZBB 1BKEA 4FK5B 5ID9A 2XMOA 4OR0A 2LQHA 4GDLB 2DBWA 2DBXA 1E78A 3NMUA 1UORA 4LUHA 2BXNA 1NT2B 2BXFA 2BXPA 2BXIA 4W4UB 5GHKA 3B9MA 5GINA 2KBZA 2XSIA 2YDFA 2BXBA 2BXDA 4K2CA 4D7XA 2EFDA 5IJFA 1MUHA 1N5UA 1E7EA 4N0UD 4I9OA 1BJ5A 4ZUXV 2BXOA 3LU7A 4MBEC 4LB9A 4K71A 3MHSB 2OT3A 4JK4A 3H37A 4G03A 5IIHA 2VUEA 4N0FD 2VUFA 3WHSA 4NAWB 3ECPA 4EMXA 3SQJA 3ICXA 3SIUB 3FNMA 4HGKA 1E7IA 2GUTA 4J2VA 4LA0A 5D7GA 4OTTA 4TQ0A 1HK1A 1MIYA 1GNJA 1HA2A 1MIVA 1LNSA 1MA9A 2CKXA 3G9KD 1TF0A 2E0YA 3H3AA 3W1SA 5FUOA 2BXKA 4WA6B 4C31B 3A75A 4F5SA 1GNIA 2DG5A 1O9XA 3SIVB 1MM8A 2BXLA 1VZSA 2K0NA 3LU8A 2Z8JA 4FJCB 3WHQA 4G01A 1HK3A 3JRYA 4S1YA 2BXGA
chains in the Genus database with same CATH topology
2E0XA 2I30A 2BXEA 2NQOA 1H9ZA 4FIPB 2VDBA 3JQZA 4G04A 3KJLA 4L9QA 4L8UA 4Z9OA 4ZCGA 4PO0A 1H5WA 5IJEA 3V09A 2QM6A 2BXMA 4L9KA 3VQIA 5DQFA 2V36A 3PLAA 3NVMA 2I2ZA 3UIVA 5BPKA 4BY9C 1HK2A 2BX8A 1VFIA 2QMCA 2EFHA 2ROHA 1KW2A 2XW0A 5IIUA 1IJGA 4N3ZA 2QHBA 2XVQA 1BM0A 3FWCC 2NNWA 4HGMB 3GQUA 3MHHB 4IW1A 5DBYA 1E7CA 4OTUA 2Z8IA 4ZBKA 3NVIA 4GG2A 4M70B 3CX9A 2DYOA 3V03A 2DBUA 2BXQA 4TQ1A 1HK5A 1AO6A 1LOTA 5GIPA 3NVKA 1E7FA 4GDXA 2BXHA 4ZBRA 4IW2A 1FOUA 5IJ5A 3WHRA 3M99C 5HOZA 3GA9L 2BXAA 5B5TA 1KXPD 2AJEA 4F5TA 1JNBA 4ZC6A 1J7EA 1TXUA 2XW1A 1E7BA 1E7AA 2LOQA 2EFEA 5ID7A 2XVVA 3FWBC 5GIOA 1E7HA 2BXCA 4GDKB 3V08A 3KIKA 4E99A 1E7GA 5IFOA 4DHXB 4LUFA 4F5VA 4LB2A 2XVUA 2JUHA 1MIWA 3B9LA 4Z69A 3GQXA 4ZBQA 1J78A 2EFCA 4BKEA 1HK4A 4F5UA 2Z8KA 2DYMA 3A73A 3LU6A 4OT2A 2XVWA 3TDLA 5IIXA 2OZBB 1BKEA 4FK5B 5ID9A 2XMOA 4OR0A 4GDLB 3NMUA 2DBWA 2DBXA 1E78A 1UORA 4LUHA 2BXNA 1NT2B 2BXFA 2BXPA 2BXIA 4W4UB 5GHKA 3B9MA 5GINA 2KBZA 2XSIA 2YDFA 2BXBA 2BXDA 4K2CA 2EFDA 5IJFA 1N5UA 1E7EA 4N0UD 1BJ5A 4ZUXV 2BXOA 3LU7A 4MBEC 4LB9A 4K71A 3MHSB 2OT3A 4JK4A 3H37A 4G03A 5IIHA 2VUEA 4N0FD 2VUFA 3WHSA 4NAWB 4EMXA 3SQJA 3ICXA 3SIUB 3FNMA 4HGKA 1E7IA 4J2VA 4LA0A 5D7GA 4OTTA 4TQ0A 1HK1A 1MIYA 1GNJA 1HA2A 1MIVA 1LNSA 1MA9A 2CKXA 3G9KD 1TF0A 2E0YA 3H3AA 3W1SA 5FUOA 2BXKA 4WA6B 4C31B 3A75A 4F5SA 1GNIA 2DG5A 1O9XA 3SIVB 2BXLA 1VZSA 3WHQA 3LU8A 2Z8JA 4FJCB 4G01A 1HK3A 3JRYA 4S1YA 2BXGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I30 A;  2BXE A;  1H9Z A;  2VDB A;  3JQZ A;  4G04 A;  4L9Q A;  4L8U A;  4PO0 A;  5IJE A;  3V09 A;  4L9K A;  2BXM A;  5DQF A;  2I2Z A;  3UIV A;  1HK2 A;  2BX8 A;  1KW2 A;  2XW0 A;  5IIU A;  2XVQ A;  1BM0 A;  4HGM B;  4IW1 A;  5DBY A;  1E7C A;  3CX9 A;  3V03 A;  2BXQ A;  1HK5 A;  1AO6 A;  1LOT A;  1E7F A;  2BXH A;  4ZBR A;  4IW2 A;  5IJ5 A;  5HOZ A;  2BXA A;  1KXP D;  4F5T A;  1J7E A;  2XW1 A;  1E7B A;  1E7A A;  5ID7 A;  2XVV A;  1E7H A;  2BXC A;  3V08 A;  4E99 A;  1E7G A;  5IFO A;  4F5V A;  4LUF A;  4LB2 A;  2XVU A;  3B9L A;  4Z69 A;  4ZBQ A;  1J78 A;  4BKE A;  1HK4 A;  4F5U A;  3A73 A;  3LU6 A;  4OT2 A;  2XVW A;  3TDL A;  5IIX A;  1BKE A;  5ID9 A;  4OR0 A;  1E78 A;  1UOR A;  4LUH A;  2BXF A;  2BXP A;  2BXN A;  2BXI A;  5GHK A;  3B9M A;  2XSI A;  2YDF A;  2BXB A;  2BXD A;  4K2C A;  5IJF A;  1N5U A;  1E7E A;  4N0U D;  1BJ5 A;  2BXO A;  3LU7 A;  4LB9 A;  4K71 A;  4JK4 A;  4G03 A;  5IIH A;  2VUE A;  4N0F D;  2VUF A;  4EMX A;  3SQJ A;  4HGK A;  1E7I A;  4J2V A;  4LA0 A;  1HK1 A;  1GNJ A;  1HA2 A;  1MA9 A;  1TF0 A;  5FUO A;  2BXK A;  4F5S A;  1GNI A;  1O9X A;  2BXL A;  3LU8 A;  1HK3 A;  3JRY A;  4S1Y A;  2BXG A; 
#chains in the Genus database with same CATH topology
 2E0X A;  2I30 A;  2BXE A;  2NQO A;  1H9Z A;  4FIP B;  2VDB A;  3JQZ A;  4G04 A;  3KJL A;  4L9Q A;  4L8U A;  4Z9O A;  4ZCG A;  4PO0 A;  1H5W A;  5IJE A;  3V09 A;  2QM6 A;  2BXM A;  4L9K A;  3VQI A;  5DQF A;  2V36 A;  3PLA A;  3NVM A;  2I2Z A;  3UIV A;  5BPK A;  4BY9 C;  1HK2 A;  2BX8 A;  1VFI A;  2QMC A;  2EFH A;  2ROH A;  1KW2 A;  2XW0 A;  5IIU A;  1IJG A;  4N3Z A;  2QHB A;  2XVQ A;  1MUS A;  1BM0 A;  3BPJ A;  3FWC C;  2NNW A;  4HGM B;  3GQU A;  3MHH B;  4IW1 A;  5DBY A;  1E7C A;  4OTU A;  2Z8I A;  4ZBK A;  3NVI A;  4GG2 A;  4M70 B;  3CX9 A;  2DYO A;  3V03 A;  2DBU A;  2AGH B;  2BXQ A;  4TQ1 A;  1HK5 A;  1AO6 A;  1LOT A;  5GIP A;  4DM0 A;  3NVK A;  1E7F A;  4GDX A;  2BXH A;  4ZBR A;  4IW2 A;  1FOU A;  5IJ5 A;  3WHR A;  3M99 C;  5HOZ A;  3GA9 L;  2BXA A;  5B5T A;  1KXP D;  2AJE A;  4F5T A;  1JNB A;  4ZC6 A;  1J7E A;  1TXU A;  2XW1 A;  1E7B A;  1E7A A;  2LOQ A;  2EFE A;  5ID7 A;  2XVV A;  3FWB C;  5GIO A;  1E7H A;  2BXC A;  4GDK B;  3V08 A;  3KIK A;  2LXS A;  4E99 A;  1E7G A;  2LXT A;  5IFO A;  4LUF A;  4DHX B;  4LB2 A;  4F5V A;  2XVU A;  2JUH A;  1MIW A;  1KDX A;  3B9L A;  4Z69 A;  3GQX A;  4ZBQ A;  1J78 A;  2EFC A;  4BKE A;  1HK4 A;  2LQI A;  4F5U A;  2Z8K A;  2DYM A;  3A73 A;  2KWF A;  3LU6 A;  1SB0 A;  2XVW A;  4OT2 A;  3TDL A;  5IIX A;  2OZB B;  1BKE A;  4FK5 B;  5ID9 A;  2XMO A;  4OR0 A;  2LQH A;  4GDL B;  2DBW A;  2DBX A;  1E78 A;  3NMU A;  1UOR A;  4LUH A;  2BXN A;  1NT2 B;  2BXF A;  2BXP A;  2BXI A;  4W4U B;  5GHK A;  3B9M A;  5GIN A;  2KBZ A;  2XSI A;  2YDF A;  2BXB A;  2BXD A;  4K2C A;  4D7X A;  2EFD A;  5IJF A;  1MUH A;  1N5U A;  1E7E A;  4N0U D;  4I9O A;  1BJ5 A;  4ZUX V;  2BXO A;  3LU7 A;  4MBE C;  4LB9 A;  4K71 A;  3MHS B;  2OT3 A;  4JK4 A;  3H37 A;  4G03 A;  5IIH A;  2VUE A;  4N0F D;  2VUF A;  3WHS A;  4NAW B;  3ECP A;  4EMX A;  3SQJ A;  3ICX A;  3SIU B;  3FNM A;  4HGK A;  1E7I A;  2GUT A;  4J2V A;  4LA0 A;  5D7G A;  4OTT A;  4TQ0 A;  1HK1 A;  1MIY A;  1GNJ A;  1HA2 A;  1MIV A;  1LNS A;  1MA9 A;  2CKX A;  3G9K D;  1TF0 A;  2E0Y A;  3H3A A;  3W1S A;  5FUO A;  2BXK A;  4WA6 B;  4C31 B;  3A75 A;  4F5S A;  1GNI A;  2DG5 A;  1O9X A;  3SIV B;  1MM8 A;  2BXL A;  1VZS A;  2K0N A;  3LU8 A;  2Z8J A;  4FJC B;  3WHQ A;  4G01 A;  1HK3 A;  3JRY A;  4S1Y A;  2BXG A; 
#chains in the Genus database with same CATH homology
 2E0X A;  2I30 A;  2BXE A;  2NQO A;  1H9Z A;  4FIP B;  2VDB A;  3JQZ A;  4G04 A;  3KJL A;  4L9Q A;  4L8U A;  4Z9O A;  4ZCG A;  4PO0 A;  1H5W A;  5IJE A;  3V09 A;  2QM6 A;  2BXM A;  4L9K A;  3VQI A;  5DQF A;  2V36 A;  3PLA A;  3NVM A;  2I2Z A;  3UIV A;  5BPK A;  4BY9 C;  1HK2 A;  2BX8 A;  1VFI A;  2QMC A;  2EFH A;  2ROH A;  1KW2 A;  2XW0 A;  5IIU A;  1IJG A;  4N3Z A;  2QHB A;  2XVQ A;  1BM0 A;  3FWC C;  2NNW A;  4HGM B;  3GQU A;  3MHH B;  4IW1 A;  5DBY A;  1E7C A;  4OTU A;  2Z8I A;  4ZBK A;  3NVI A;  4GG2 A;  4M70 B;  3CX9 A;  2DYO A;  3V03 A;  2DBU A;  2BXQ A;  4TQ1 A;  1HK5 A;  1AO6 A;  1LOT A;  5GIP A;  3NVK A;  1E7F A;  4GDX A;  2BXH A;  4ZBR A;  4IW2 A;  1FOU A;  5IJ5 A;  3WHR A;  3M99 C;  5HOZ A;  3GA9 L;  2BXA A;  5B5T A;  1KXP D;  2AJE A;  4F5T A;  1JNB A;  4ZC6 A;  1J7E A;  1TXU A;  2XW1 A;  1E7B A;  1E7A A;  2LOQ A;  2EFE A;  5ID7 A;  2XVV A;  3FWB C;  5GIO A;  1E7H A;  2BXC A;  4GDK B;  3V08 A;  3KIK A;  4E99 A;  1E7G A;  5IFO A;  4DHX B;  4LUF A;  4F5V A;  4LB2 A;  2XVU A;  2JUH A;  1MIW A;  3B9L A;  4Z69 A;  3GQX A;  4ZBQ A;  1J78 A;  2EFC A;  4BKE A;  1HK4 A;  4F5U A;  2Z8K A;  2DYM A;  3A73 A;  3LU6 A;  4OT2 A;  2XVW A;  3TDL A;  5IIX A;  2OZB B;  1BKE A;  4FK5 B;  5ID9 A;  2XMO A;  4OR0 A;  4GDL B;  3NMU A;  2DBW A;  2DBX A;  1E78 A;  1UOR A;  4LUH A;  2BXN A;  1NT2 B;  2BXF A;  2BXP A;  2BXI A;  4W4U B;  5GHK A;  3B9M A;  5GIN A;  2KBZ A;  2XSI A;  2YDF A;  2BXB A;  2BXD A;  4K2C A;  2EFD A;  5IJF A;  1N5U A;  1E7E A;  4N0U D;  1BJ5 A;  4ZUX V;  2BXO A;  3LU7 A;  4MBE C;  4LB9 A;  4K71 A;  3MHS B;  2OT3 A;  4JK4 A;  3H37 A;  4G03 A;  5IIH A;  2VUE A;  4N0F D;  2VUF A;  3WHS A;  4NAW B;  4EMX A;  3SQJ A;  3ICX A;  3SIU B;  3FNM A;  4HGK A;  1E7I A;  4J2V A;  4LA0 A;  5D7G A;  4OTT A;  4TQ0 A;  1HK1 A;  1MIY A;  1GNJ A;  1HA2 A;  1MIV A;  1LNS A;  1MA9 A;  2CKX A;  3G9K D;  1TF0 A;  2E0Y A;  3H3A A;  3W1S A;  5FUO A;  2BXK A;  4WA6 B;  4C31 B;  3A75 A;  4F5S A;  1GNI A;  2DG5 A;  1O9X A;  3SIV B;  2BXL A;  1VZS A;  3WHQ A;  3LU8 A;  2Z8J A;  4FJC B;  4G01 A;  1HK3 A;  3JRY A;  4S1Y A;  2BXG A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...