1E7CA

Human serum albumin complexed with myristic acid and the general anesthetic halothane
Total Genus 214
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
214
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords SERUM ALBUMIN
publication title Binding of the General Anesthetics Propofol and Halothane to Human Serum Albumin. High Resolution Crystal Structures
pubmed doi rcsb
source organism Homo sapiens
molecule tags Plasma protein
total genus 214
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2000-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e7cA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e7cA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e7cA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e7cA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e7cA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1e7cA05
2BX8A 1KW2A 4BKEA 4K2CA 1N5UA 4HGKA 4LA0A 2XVWA 4N0UD 2XW0A 1BKEA 1HK3A 1LOTA 1E7CA 4EMXA 1HK4A 3UIVA 4S1YA 2BXNA 4HGMB 4L9KA 2BXOA 5IFOA 3TDLA 2BXFA 4IW1A 2XVQA 5GHKA 2YDFA 2I2ZA 4LUFA 4OR0A 5HOZA 5IJFA 2BXCA 4ZBRA 3LU6A 2VUEA 5FUOA 5IIUA 1E7FA 5IJEA 1J78A 2BXQA 2BXHA 5IIHA 3CX9A 1O9XA 3A73A 2BXLA 4JK4A 2I30A 2BXMA 3JQZA 3SQJA 1E7GA 1E7HA 2BXGA 4LB2A 2BXEA 1KXPD 1HK5A 1TF0A 4F5UA 1HK1A 1UORA 2XW1A 1BM0A 5ID9A 4F5SA 3B9MA 4PO0A 4J2VA 1H9ZA 1HK2A 4OT2A 2BXDA 1E7AA 4K71A 3LU8A 1HA2A 1E7BA 4L8UA 2BXBA 1J7EA 2XVVA 3V03A 1E7IA 2BXPA 2BXAA 4L9QA 5ID7A 2BXIA 5DQFA 2VDBA 2BXKA 3V09A 4F5TA 4Z69A 2VUFA 4IW2A 3V08A 2XSIA 4LB9A 4N0FD 5DBYA 4ZBQA 5IJ5A 1E7EA 3JRYA 4G04A 3B9LA 3LU7A 4E99A 2XVUA 1AO6A 4LUHA 1BJ5A 1GNJA 4G03A 1E78A 1MA9A 4F5VA 1GNIA 5IIXA
chains in the Genus database with same CATH superfamily
5D7GA 2BX8A 3MHHB 1KW2A 3NVMA 4NAWB 1TXUA 3NMUA 2DYMA 4K2CA 4BKEA 4D7XA 2DBXA 2QHBA 1N5UA 4HGKA 2LQHA 4LA0A 2E0XA 3A75A 2XVWA 4N0UD 2XW0A 1JNBA 2V36A 1MUSA 2NNWA 1BKEA 2LOQA 1HK3A 1LOTA 3GA9L 2NQOA 1E7CA 4GDLB 3H3AA 4TQ1A 2QM6A 4EMXA 3VQIA 4BY9C 1HK4A 4FK5B 2OT3A 3GQUA 4ZBKA 4N3ZA 4S1YA 3UIVA 2BXNA 4HGMB 3KJLA 2BXOA 4L9KA 5IFOA 3TDLA 2BXFA 3WHRA 4IW1A 2XVQA 5GHKA 2YDFA 4W4UB 2I2ZA 4LUFA 4OR0A 3WHSA 5B5TA 5GIOA 5HOZA 3ICXA 2BXCA 5IJFA 2GUTA 4GDKB 4ZBRA 1NT2B 2DBUA 2Z8IA 2DBWA 2JUHA 2VUEA 3LU6A 5FUOA 1E7FA 5IIUA 4G01A 5IJEA 1J78A 2BXQA 2BXHA 5IIHA 3CX9A 3W1SA 1O9XA 4DHXB 3A73A 2BXLA 1IJGA 4JK4A 2AJEA 4OTUA 2I30A 1MM8A 2BXMA 2LQIA 3G9KD 3JQZA 4ZC6A 3SQJA 1E7GA 3BPJA 1E7HA 2DYOA 2BXGA 4LB2A 2KWFA 2BXEA 2Z8JA 1KXPD 4GG2A 1HK5A 1VFIA 1SB0A 4Z9OA 1TF0A 4ZCGA 4F5UA 2E0YA 1HK1A 1UORA 2XW1A 2EFCA 1MUHA 1BM0A 5ID9A 1LNSA 4F5SA 3B9MA 4PO0A 4J2VA 2Z8KA 1H9ZA 1HK2A 4OT2A 2BXDA 3FWCC 3NVIA 1KDXA 4OTTA 1E7AA 4K71A 3LU8A 1HA2A 1E7BA 2KBZA 4L8UA 2BXBA 1J7EA 1MIWA 2XVVA 4FIPB 3V03A 1E7IA 2BXPA 2CKXA 2BXAA 4L9QA 2LXSA 1FOUA 5ID7A 2BXIA 5DQFA 2EFEA 2VDBA 4I9OA 2BXKA 4ZUXV 4C31B 2K0NA 3V09A 4F5TA 3SIVB 1MIVA 2EFDA 2LXTA 4Z69A 2VUFA 4IW2A 2QMCA 5BPKA 4DM0A 3V08A 3PLAA 3FNMA 3ECPA 2XSIA 4LB9A 4N0FD 5GINA 5DBYA 4ZBQA 5IJ5A 3MHSB 2ROHA 3M99C 3H37A 1E7EA 3SIUB 4WA6B 3NVKA 3JRYA 4G04A 2DG5A 1MIYA 5GIPA 2XMOA 3B9LA 1VZSA 3LU7A 4E99A 2XVUA 3FWBC 4LUHA 1AO6A 3KIKA 1BJ5A 1GNJA 4M70B 4G03A 1E78A 1MA9A 3WHQA 2EFHA 2AGHB 4FJCB 4F5VA 4MBEC 1H5WA 1GNIA 4GDXA 4TQ0A 3GQXA 2OZBB 5IIXA
chains in the Genus database with same CATH topology
5D7GA 2BX8A 3MHHB 1KW2A 3NVMA 4NAWB 1TXUA 3NMUA 2DYMA 4K2CA 4BKEA 2DBXA 2QHBA 1N5UA 4HGKA 4LA0A 2E0XA 3A75A 2XVWA 4N0UD 2XW0A 1JNBA 2V36A 2NNWA 1BKEA 2LOQA 1HK3A 1LOTA 3GA9L 2NQOA 1E7CA 4GDLB 3H3AA 4TQ1A 2QM6A 4EMXA 3VQIA 4BY9C 1HK4A 4FK5B 2OT3A 3GQUA 4ZBKA 4N3ZA 4S1YA 3UIVA 2BXNA 4HGMB 3KJLA 2BXOA 4L9KA 5IFOA 3TDLA 2BXFA 3WHRA 4IW1A 2XVQA 5GHKA 2YDFA 4W4UB 2I2ZA 4LUFA 4OR0A 3WHSA 5B5TA 5GIOA 5HOZA 3ICXA 2BXCA 5IJFA 4GDKB 4ZBRA 1NT2B 2DBUA 2Z8IA 2DBWA 2JUHA 2VUEA 3LU6A 5FUOA 1E7FA 5IIUA 4G01A 5IJEA 1J78A 2BXQA 2BXHA 5IIHA 3CX9A 3W1SA 1O9XA 4DHXB 3A73A 2BXLA 1IJGA 4JK4A 2AJEA 4OTUA 2I30A 2BXMA 3JQZA 3G9KD 4ZC6A 3SQJA 1E7GA 1E7HA 2DYOA 2BXGA 4LB2A 2BXEA 2Z8JA 1KXPD 4GG2A 1HK5A 1VFIA 4Z9OA 1TF0A 4ZCGA 4F5UA 2E0YA 1HK1A 1UORA 2XW1A 2EFCA 1BM0A 5ID9A 1LNSA 4F5SA 3B9MA 4PO0A 4J2VA 2Z8KA 1H9ZA 1HK2A 4OT2A 2BXDA 3FWCC 3NVIA 4OTTA 1E7AA 4K71A 3LU8A 1HA2A 1E7BA 2KBZA 4L8UA 2BXBA 1J7EA 1MIWA 2XVVA 4FIPB 3V03A 1E7IA 2BXPA 2CKXA 2BXAA 4L9QA 1FOUA 5ID7A 2BXIA 5DQFA 2EFEA 2VDBA 2BXKA 4ZUXV 4C31B 3V09A 4F5TA 3SIVB 1MIVA 2EFDA 4Z69A 2VUFA 4IW2A 2QMCA 5BPKA 3V08A 3PLAA 3FNMA 2XSIA 4LB9A 4N0FD 5GINA 5DBYA 4ZBQA 5IJ5A 3MHSB 2ROHA 3M99C 3H37A 1E7EA 3SIUB 4WA6B 3NVKA 3JRYA 4G04A 2DG5A 1MIYA 5GIPA 2XMOA 3B9LA 1VZSA 3LU7A 4E99A 2XVUA 3FWBC 4LUHA 1AO6A 3KIKA 1BJ5A 1GNJA 4M70B 4G03A 1E78A 1MA9A 3WHQA 2EFHA 4FJCB 4F5VA 4MBEC 1H5WA 1GNIA 4GDXA 4TQ0A 3GQXA 2OZBB 5IIXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BX8 A;  1KW2 A;  4BKE A;  4K2C A;  1N5U A;  4HGK A;  4LA0 A;  2XVW A;  4N0U D;  2XW0 A;  1BKE A;  1HK3 A;  1LOT A;  1E7C A;  4EMX A;  1HK4 A;  3UIV A;  4S1Y A;  2BXN A;  4HGM B;  4L9K A;  2BXO A;  5IFO A;  3TDL A;  2BXF A;  4IW1 A;  2XVQ A;  5GHK A;  2YDF A;  2I2Z A;  4LUF A;  4OR0 A;  5HOZ A;  5IJF A;  2BXC A;  4ZBR A;  3LU6 A;  2VUE A;  5FUO A;  5IIU A;  1E7F A;  5IJE A;  1J78 A;  2BXQ A;  2BXH A;  5IIH A;  3CX9 A;  1O9X A;  3A73 A;  2BXL A;  4JK4 A;  2I30 A;  2BXM A;  3JQZ A;  3SQJ A;  1E7G A;  1E7H A;  2BXG A;  4LB2 A;  2BXE A;  1KXP D;  1HK5 A;  1TF0 A;  4F5U A;  1HK1 A;  1UOR A;  2XW1 A;  1BM0 A;  5ID9 A;  4F5S A;  3B9M A;  4PO0 A;  4J2V A;  1H9Z A;  1HK2 A;  4OT2 A;  2BXD A;  1E7A A;  4K71 A;  3LU8 A;  1HA2 A;  1E7B A;  4L8U A;  2BXB A;  1J7E A;  2XVV A;  3V03 A;  1E7I A;  2BXP A;  2BXA A;  4L9Q A;  5ID7 A;  2BXI A;  5DQF A;  2VDB A;  2BXK A;  3V09 A;  4F5T A;  4Z69 A;  2VUF A;  4IW2 A;  3V08 A;  2XSI A;  4LB9 A;  4N0F D;  5DBY A;  4ZBQ A;  5IJ5 A;  1E7E A;  3JRY A;  4G04 A;  3B9L A;  3LU7 A;  4E99 A;  2XVU A;  1AO6 A;  4LUH A;  1BJ5 A;  1GNJ A;  4G03 A;  1E78 A;  1MA9 A;  4F5V A;  1GNI A;  5IIX A; 
#chains in the Genus database with same CATH topology
 5D7G A;  2BX8 A;  3MHH B;  1KW2 A;  3NVM A;  4NAW B;  1TXU A;  3NMU A;  2DYM A;  4K2C A;  4BKE A;  4D7X A;  2DBX A;  2QHB A;  1N5U A;  4HGK A;  2LQH A;  4LA0 A;  2E0X A;  3A75 A;  2XVW A;  4N0U D;  2XW0 A;  1JNB A;  2V36 A;  1MUS A;  2NNW A;  1BKE A;  2LOQ A;  1HK3 A;  1LOT A;  3GA9 L;  2NQO A;  1E7C A;  4GDL B;  3H3A A;  4TQ1 A;  2QM6 A;  4EMX A;  3VQI A;  4BY9 C;  1HK4 A;  4FK5 B;  2OT3 A;  3GQU A;  4ZBK A;  4N3Z A;  4S1Y A;  3UIV A;  2BXN A;  4HGM B;  3KJL A;  2BXO A;  4L9K A;  5IFO A;  3TDL A;  2BXF A;  3WHR A;  4IW1 A;  2XVQ A;  5GHK A;  2YDF A;  4W4U B;  2I2Z A;  4LUF A;  4OR0 A;  3WHS A;  5B5T A;  5GIO A;  5HOZ A;  3ICX A;  2BXC A;  5IJF A;  2GUT A;  4GDK B;  4ZBR A;  1NT2 B;  2DBU A;  2Z8I A;  2DBW A;  2JUH A;  2VUE A;  3LU6 A;  5FUO A;  1E7F A;  5IIU A;  4G01 A;  5IJE A;  1J78 A;  2BXQ A;  2BXH A;  5IIH A;  3CX9 A;  3W1S A;  1O9X A;  4DHX B;  3A73 A;  2BXL A;  1IJG A;  4JK4 A;  2AJE A;  4OTU A;  2I30 A;  1MM8 A;  2BXM A;  2LQI A;  3G9K D;  3JQZ A;  4ZC6 A;  3SQJ A;  1E7G A;  3BPJ A;  1E7H A;  2DYO A;  2BXG A;  4LB2 A;  2KWF A;  2BXE A;  2Z8J A;  1KXP D;  4GG2 A;  1HK5 A;  1VFI A;  1SB0 A;  4Z9O A;  1TF0 A;  4ZCG A;  4F5U A;  2E0Y A;  1HK1 A;  1UOR A;  2XW1 A;  2EFC A;  1MUH A;  1BM0 A;  5ID9 A;  1LNS A;  4F5S A;  3B9M A;  4PO0 A;  4J2V A;  2Z8K A;  1H9Z A;  1HK2 A;  4OT2 A;  2BXD A;  3FWC C;  3NVI A;  1KDX A;  4OTT A;  1E7A A;  4K71 A;  3LU8 A;  1HA2 A;  1E7B A;  2KBZ A;  4L8U A;  2BXB A;  1J7E A;  1MIW A;  2XVV A;  4FIP B;  3V03 A;  1E7I A;  2BXP A;  2CKX A;  2BXA A;  4L9Q A;  2LXS A;  1FOU A;  5ID7 A;  2BXI A;  5DQF A;  2EFE A;  2VDB A;  4I9O A;  2BXK A;  4ZUX V;  4C31 B;  2K0N A;  3V09 A;  4F5T A;  3SIV B;  1MIV A;  2EFD A;  2LXT A;  4Z69 A;  2VUF A;  4IW2 A;  2QMC A;  5BPK A;  4DM0 A;  3V08 A;  3PLA A;  3FNM A;  3ECP A;  2XSI A;  4LB9 A;  4N0F D;  5GIN A;  5DBY A;  4ZBQ A;  5IJ5 A;  3MHS B;  2ROH A;  3M99 C;  3H37 A;  1E7E A;  3SIU B;  4WA6 B;  3NVK A;  3JRY A;  4G04 A;  2DG5 A;  1MIY A;  5GIP A;  2XMO A;  3B9L A;  1VZS A;  3LU7 A;  4E99 A;  2XVU A;  3FWB C;  4LUH A;  1AO6 A;  3KIK A;  1BJ5 A;  1GNJ A;  4M70 B;  4G03 A;  1E78 A;  1MA9 A;  3WHQ A;  2EFH A;  2AGH B;  4FJC B;  4F5V A;  4MBE C;  1H5W A;  1GNI A;  4GDX A;  4TQ0 A;  3GQX A;  2OZB B;  5IIX A; 
#chains in the Genus database with same CATH homology
 5D7G A;  2BX8 A;  3MHH B;  1KW2 A;  3NVM A;  4NAW B;  1TXU A;  3NMU A;  2DYM A;  4K2C A;  4BKE A;  2DBX A;  2QHB A;  1N5U A;  4HGK A;  4LA0 A;  2E0X A;  3A75 A;  2XVW A;  4N0U D;  2XW0 A;  1JNB A;  2V36 A;  2NNW A;  1BKE A;  2LOQ A;  1HK3 A;  1LOT A;  3GA9 L;  2NQO A;  1E7C A;  4GDL B;  3H3A A;  4TQ1 A;  2QM6 A;  4EMX A;  3VQI A;  4BY9 C;  1HK4 A;  4FK5 B;  2OT3 A;  3GQU A;  4ZBK A;  4N3Z A;  4S1Y A;  3UIV A;  2BXN A;  4HGM B;  3KJL A;  2BXO A;  4L9K A;  5IFO A;  3TDL A;  2BXF A;  3WHR A;  4IW1 A;  2XVQ A;  5GHK A;  2YDF A;  4W4U B;  2I2Z A;  4LUF A;  4OR0 A;  3WHS A;  5B5T A;  5GIO A;  5HOZ A;  3ICX A;  2BXC A;  5IJF A;  4GDK B;  4ZBR A;  1NT2 B;  2DBU A;  2Z8I A;  2DBW A;  2JUH A;  2VUE A;  3LU6 A;  5FUO A;  1E7F A;  5IIU A;  4G01 A;  5IJE A;  1J78 A;  2BXQ A;  2BXH A;  5IIH A;  3CX9 A;  3W1S A;  1O9X A;  4DHX B;  3A73 A;  2BXL A;  1IJG A;  4JK4 A;  2AJE A;  4OTU A;  2I30 A;  2BXM A;  3JQZ A;  3G9K D;  4ZC6 A;  3SQJ A;  1E7G A;  1E7H A;  2DYO A;  2BXG A;  4LB2 A;  2BXE A;  2Z8J A;  1KXP D;  4GG2 A;  1HK5 A;  1VFI A;  4Z9O A;  1TF0 A;  4ZCG A;  4F5U A;  2E0Y A;  1HK1 A;  1UOR A;  2XW1 A;  2EFC A;  1BM0 A;  5ID9 A;  1LNS A;  4F5S A;  3B9M A;  4PO0 A;  4J2V A;  2Z8K A;  1H9Z A;  1HK2 A;  4OT2 A;  2BXD A;  3FWC C;  3NVI A;  4OTT A;  1E7A A;  4K71 A;  3LU8 A;  1HA2 A;  1E7B A;  2KBZ A;  4L8U A;  2BXB A;  1J7E A;  1MIW A;  2XVV A;  4FIP B;  3V03 A;  1E7I A;  2BXP A;  2CKX A;  2BXA A;  4L9Q A;  1FOU A;  5ID7 A;  2BXI A;  5DQF A;  2EFE A;  2VDB A;  2BXK A;  4ZUX V;  4C31 B;  3V09 A;  4F5T A;  3SIV B;  1MIV A;  2EFD A;  4Z69 A;  2VUF A;  4IW2 A;  2QMC A;  5BPK A;  3V08 A;  3PLA A;  3FNM A;  2XSI A;  4LB9 A;  4N0F D;  5GIN A;  5DBY A;  4ZBQ A;  5IJ5 A;  3MHS B;  2ROH A;  3M99 C;  3H37 A;  1E7E A;  3SIU B;  4WA6 B;  3NVK A;  3JRY A;  4G04 A;  2DG5 A;  1MIY A;  5GIP A;  2XMO A;  3B9L A;  1VZS A;  3LU7 A;  4E99 A;  2XVU A;  3FWB C;  4LUH A;  1AO6 A;  3KIK A;  1BJ5 A;  1GNJ A;  4M70 B;  4G03 A;  1E78 A;  1MA9 A;  3WHQ A;  2EFH A;  4FJC B;  4F5V A;  4MBE C;  1H5W A;  1GNI A;  4GDX A;  4TQ0 A;  3GQX A;  2OZB B;  5IIX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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