4E99A

Human serum albumin complex with perfluorooctane sulfonate potassium
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
567
structure length
554
Chain Sequence
SEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Serum albumin
publication title Structural evidence of perfluorooctane sulfonate transport by human serum albumin
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 226
structure length 554
sequence length 567
ec nomenclature
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4e99A05
1GNJA 2BXFA 4BKEA 4J2VA 2XVQA 4ZBRA 3A73A 1BKEA 3SQJA 1E7EA 2XVVA 4F5TA 1MA9A 2BXGA 1E7FA 1HK1A 4G03A 4LUHA 5ID9A 4IW2A 1HK2A 3V09A 1E7BA 2BX8A 1E78A 2XVUA 4L9QA 1KXPD 1H9ZA 4IW1A 4LB9A 4N0UD 2I2ZA 5IJEA 2XVWA 4G04A 1GNIA 2BXQA 5IFOA 4OR0A 3LU8A 3TDLA 4LUFA 5GHKA 2VUEA 2VDBA 1TF0A 5IIXA 5DBYA 2XW0A 4LB2A 3JRYA 5ID7A 4L9KA 2BXIA 2BXMA 1BJ5A 3B9MA 4EMXA 3B9LA 1E7IA 1N5UA 4L8UA 4S1YA 1AO6A 1J7EA 4Z69A 4JK4A 4F5SA 4LA0A 1HA2A 2BXOA 2BXHA 4N0FD 5DQFA 2XW1A 4PO0A 1HK5A 4K2CA 1J78A 5IIUA 3UIVA 3V03A 2BXLA 2VUFA 2BXDA 3LU6A 1LOTA 4K71A 5IJFA 1E7HA 2BXKA 2BXBA 1E7AA 2BXNA 3CX9A 2BXEA 2BXPA 1E7GA 4E99A 2BXAA 1HK4A 5IJ5A 1E7CA 2BXCA 4OT2A 5FUOA 4HGKA 5IIHA 1BM0A 1HK3A 3V08A 3LU7A 1O9XA 4HGMB 4F5UA 2I30A 2XSIA 2YDFA 1UORA 4ZBQA 1KW2A 3JQZA 4F5VA 5HOZA
chains in the Genus database with same CATH superfamily
1GNJA 4GDXA 2BXFA 3M99C 4BKEA 4FJCB 2ROHA 4J2VA 2LOQA 1MIWA 2XVQA 2Z8KA 4ZBRA 3H3AA 3NMUA 4DHXB 3A73A 1BKEA 1MIVA 2NQOA 1SB0A 3SQJA 2AJEA 3W1SA 1MUSA 1E7EA 2LXTA 3KJLA 2XVVA 4W4UB 1MA9A 4F5TA 4OTTA 4FK5B 2BXGA 1E7FA 1HK1A 4G03A 4LUHA 5ID9A 1MM8A 3NVIA 4IW2A 1HK2A 1NT2B 3V09A 2LQHA 4TQ0A 3PLAA 2LQIA 1E7BA 2BX8A 5BPKA 1E78A 2XVUA 4L9QA 1KXPD 1H9ZA 4IW1A 4DM0A 2Z8IA 4LB9A 2I2ZA 2LXSA 4N0UD 5IJEA 2E0YA 1FOUA 2XVWA 3WHSA 4BY9C 3FWCC 4G04A 1GNIA 3GQXA 3H37A 3FNMA 4WA6B 2BXQA 2EFCA 2JUHA 5IFOA 2DBXA 4OR0A 3LU8A 3TDLA 4M70B 4LUFA 5GHKA 2VUEA 2K0NA 2VDBA 4N3ZA 4GDLB 4ZC6A 1TF0A 3WHQA 2EFHA 2DYOA 4D7XA 3BPJA 5IIXA 5DBYA 2XW0A 5D7GA 1VZSA 3JRYA 1MIYA 3FWBC 2GUTA 4LB2A 4G01A 5ID7A 4ZUXV 2OT3A 2BXIA 4L9KA 2BXMA 3G9KD 2KBZA 1BJ5A 3B9MA 3VQIA 5B5TA 4EMXA 3B9LA 1E7IA 3SIUB 1N5UA 4OTUA 4L8UA 4S1YA 1AO6A 2NNWA 1J7EA 3GQUA 4Z69A 4JK4A 3KIKA 4F5SA 3ICXA 4GG2A 4LA0A 1HA2A 2BXOA 1VFIA 4C31B 4TQ1A 2BXHA 4N0FD 3ECPA 5DQFA 2XW1A 4PO0A 2OZBB 1HK5A 3GA9L 2E0XA 4K2CA 5GIOA 1J78A 2CKXA 5IIUA 3UIVA 4ZCGA 2EFDA 2BXLA 3V03A 2VUFA 2BXDA 3LU6A 1MUHA 1LOTA 3WHRA 5GINA 4K71A 5IJFA 1E7HA 2DBWA 3NVKA 2AGHB 2BXKA 4GDKB 2BXBA 1E7AA 2BXNA 3CX9A 2BXEA 2BXPA 2Z8JA 1E7GA 4ZBKA 4E99A 2BXAA 3SIVB 1HK4A 5IJ5A 1E7CA 2BXCA 2QMCA 4OT2A 1LNSA 5FUOA 2QHBA 2KWFA 3NVMA 4HGKA 5IIHA 2V36A 1BM0A 3A75A 1HK3A 2DBUA 4Z9OA 3V08A 4I9OA 1IJGA 3LU7A 1O9XA 1H5WA 2DYMA 4HGMB 2QM6A 4FIPB 4F5UA 2EFEA 2DG5A 2I30A 2XSIA 2XMOA 3MHHB 3MHSB 2YDFA 1UORA 5GIPA 4ZBQA 1TXUA 1KW2A 1KDXA 3JQZA 1JNBA 4NAWB 4MBEC 4F5VA 5HOZA
chains in the Genus database with same CATH topology
1GNJA 4GDXA 2BXFA 3M99C 4BKEA 4FJCB 2ROHA 4J2VA 2LOQA 1MIWA 2XVQA 2Z8KA 4ZBRA 3H3AA 3NMUA 4DHXB 3A73A 1BKEA 1MIVA 2NQOA 3SQJA 3W1SA 2AJEA 1E7EA 3KJLA 2XVVA 4W4UB 1MA9A 4F5TA 4OTTA 4FK5B 2BXGA 1E7FA 1HK1A 4G03A 4LUHA 5ID9A 3NVIA 4IW2A 1HK2A 1NT2B 3V09A 4TQ0A 3PLAA 1E7BA 2BX8A 5BPKA 1E78A 2XVUA 4L9QA 1KXPD 1H9ZA 4IW1A 2Z8IA 4LB9A 2I2ZA 4N0UD 5IJEA 2E0YA 1FOUA 2XVWA 3WHSA 4BY9C 3FWCC 4G04A 1GNIA 3GQXA 3H37A 3FNMA 4WA6B 2BXQA 2EFCA 2JUHA 5IFOA 2DBXA 4OR0A 3LU8A 3TDLA 4M70B 4LUFA 5GHKA 2VUEA 2VDBA 4N3ZA 4GDLB 4ZC6A 1TF0A 3WHQA 2EFHA 2DYOA 5IIXA 5DBYA 2XW0A 5D7GA 1VZSA 3JRYA 1MIYA 3FWBC 4LB2A 5ID7A 4G01A 4ZUXV 2OT3A 2BXIA 4L9KA 2BXMA 3G9KD 2KBZA 1BJ5A 3B9MA 3VQIA 5B5TA 4EMXA 3B9LA 1E7IA 3SIUB 1N5UA 4OTUA 4L8UA 4S1YA 1AO6A 2NNWA 1J7EA 3GQUA 4Z69A 4JK4A 3KIKA 4F5SA 3ICXA 4GG2A 4LA0A 1HA2A 2BXOA 1VFIA 4C31B 4TQ1A 2BXHA 4N0FD 5DQFA 2XW1A 4PO0A 2OZBB 1HK5A 3GA9L 2E0XA 4K2CA 5GIOA 1J78A 2CKXA 5IIUA 3UIVA 4ZCGA 2EFDA 2BXLA 3V03A 2VUFA 2BXDA 3LU6A 1LOTA 3WHRA 5GINA 4K71A 5IJFA 1E7HA 2DBWA 3NVKA 2BXKA 4GDKB 2BXBA 1E7AA 2BXNA 3CX9A 2BXEA 2BXPA 2Z8JA 1E7GA 4ZBKA 4E99A 2BXAA 3SIVB 1HK4A 5IJ5A 1E7CA 2BXCA 2QMCA 4OT2A 1LNSA 5FUOA 2QHBA 3NVMA 4HGKA 5IIHA 2V36A 1BM0A 3A75A 1HK3A 2DBUA 4Z9OA 3V08A 1IJGA 3LU7A 1O9XA 1H5WA 2DYMA 4HGMB 2QM6A 4FIPB 4F5UA 2EFEA 2DG5A 2I30A 2XSIA 2XMOA 3MHHB 3MHSB 2YDFA 1UORA 5GIPA 4ZBQA 1TXUA 1KW2A 3JQZA 1JNBA 4NAWB 4MBEC 4F5VA 5HOZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GNJ A;  2BXF A;  4BKE A;  4J2V A;  2XVQ A;  4ZBR A;  3A73 A;  1BKE A;  3SQJ A;  1E7E A;  2XVV A;  4F5T A;  1MA9 A;  2BXG A;  1E7F A;  1HK1 A;  4G03 A;  4LUH A;  5ID9 A;  4IW2 A;  1HK2 A;  3V09 A;  1E7B A;  2BX8 A;  1E78 A;  2XVU A;  4L9Q A;  1KXP D;  1H9Z A;  4IW1 A;  4LB9 A;  4N0U D;  2I2Z A;  5IJE A;  2XVW A;  4G04 A;  1GNI A;  2BXQ A;  5IFO A;  4OR0 A;  3LU8 A;  3TDL A;  4LUF A;  5GHK A;  2VUE A;  2VDB A;  1TF0 A;  5IIX A;  5DBY A;  2XW0 A;  4LB2 A;  3JRY A;  5ID7 A;  4L9K A;  2BXI A;  2BXM A;  1BJ5 A;  3B9M A;  4EMX A;  3B9L A;  1E7I A;  1N5U A;  4L8U A;  4S1Y A;  1AO6 A;  1J7E A;  4Z69 A;  4JK4 A;  4F5S A;  4LA0 A;  1HA2 A;  2BXO A;  2BXH A;  4N0F D;  5DQF A;  2XW1 A;  4PO0 A;  1HK5 A;  4K2C A;  1J78 A;  5IIU A;  3UIV A;  3V03 A;  2BXL A;  2VUF A;  2BXD A;  3LU6 A;  1LOT A;  4K71 A;  5IJF A;  1E7H A;  2BXK A;  2BXB A;  1E7A A;  2BXN A;  3CX9 A;  2BXE A;  2BXP A;  1E7G A;  4E99 A;  2BXA A;  1HK4 A;  5IJ5 A;  1E7C A;  2BXC A;  4OT2 A;  5FUO A;  4HGK A;  5IIH A;  1BM0 A;  1HK3 A;  3V08 A;  3LU7 A;  1O9X A;  4HGM B;  4F5U A;  2I30 A;  2XSI A;  2YDF A;  1UOR A;  4ZBQ A;  1KW2 A;  3JQZ A;  4F5V A;  5HOZ A; 
#chains in the Genus database with same CATH topology
 1GNJ A;  4GDX A;  2BXF A;  3M99 C;  4BKE A;  4FJC B;  2ROH A;  4J2V A;  2LOQ A;  1MIW A;  2XVQ A;  2Z8K A;  4ZBR A;  3H3A A;  3NMU A;  4DHX B;  3A73 A;  1BKE A;  1MIV A;  2NQO A;  1SB0 A;  3SQJ A;  2AJE A;  3W1S A;  1MUS A;  1E7E A;  2LXT A;  3KJL A;  2XVV A;  4W4U B;  1MA9 A;  4F5T A;  4OTT A;  4FK5 B;  2BXG A;  1E7F A;  1HK1 A;  4G03 A;  4LUH A;  5ID9 A;  1MM8 A;  3NVI A;  4IW2 A;  1HK2 A;  1NT2 B;  3V09 A;  2LQH A;  4TQ0 A;  3PLA A;  2LQI A;  1E7B A;  2BX8 A;  5BPK A;  1E78 A;  2XVU A;  4L9Q A;  1KXP D;  1H9Z A;  4IW1 A;  4DM0 A;  2Z8I A;  4LB9 A;  2I2Z A;  2LXS A;  4N0U D;  5IJE A;  2E0Y A;  1FOU A;  2XVW A;  3WHS A;  4BY9 C;  3FWC C;  4G04 A;  1GNI A;  3GQX A;  3H37 A;  3FNM A;  4WA6 B;  2BXQ A;  2EFC A;  2JUH A;  5IFO A;  2DBX A;  4OR0 A;  3LU8 A;  3TDL A;  4M70 B;  4LUF A;  5GHK A;  2VUE A;  2K0N A;  2VDB A;  4N3Z A;  4GDL B;  4ZC6 A;  1TF0 A;  3WHQ A;  2EFH A;  2DYO A;  4D7X A;  3BPJ A;  5IIX A;  5DBY A;  2XW0 A;  5D7G A;  1VZS A;  3JRY A;  1MIY A;  3FWB C;  2GUT A;  4LB2 A;  4G01 A;  5ID7 A;  4ZUX V;  2OT3 A;  2BXI A;  4L9K A;  2BXM A;  3G9K D;  2KBZ A;  1BJ5 A;  3B9M A;  3VQI A;  5B5T A;  4EMX A;  3B9L A;  1E7I A;  3SIU B;  1N5U A;  4OTU A;  4L8U A;  4S1Y A;  1AO6 A;  2NNW A;  1J7E A;  3GQU A;  4Z69 A;  4JK4 A;  3KIK A;  4F5S A;  3ICX A;  4GG2 A;  4LA0 A;  1HA2 A;  2BXO A;  1VFI A;  4C31 B;  4TQ1 A;  2BXH A;  4N0F D;  3ECP A;  5DQF A;  2XW1 A;  4PO0 A;  2OZB B;  1HK5 A;  3GA9 L;  2E0X A;  4K2C A;  5GIO A;  1J78 A;  2CKX A;  5IIU A;  3UIV A;  4ZCG A;  2EFD A;  2BXL A;  3V03 A;  2VUF A;  2BXD A;  3LU6 A;  1MUH A;  1LOT A;  3WHR A;  5GIN A;  4K71 A;  5IJF A;  1E7H A;  2DBW A;  3NVK A;  2AGH B;  2BXK A;  4GDK B;  2BXB A;  1E7A A;  2BXN A;  3CX9 A;  2BXE A;  2BXP A;  2Z8J A;  1E7G A;  4ZBK A;  4E99 A;  2BXA A;  3SIV B;  1HK4 A;  5IJ5 A;  1E7C A;  2BXC A;  2QMC A;  4OT2 A;  1LNS A;  5FUO A;  2QHB A;  2KWF A;  3NVM A;  4HGK A;  5IIH A;  2V36 A;  1BM0 A;  3A75 A;  1HK3 A;  2DBU A;  4Z9O A;  3V08 A;  4I9O A;  1IJG A;  3LU7 A;  1O9X A;  1H5W A;  2DYM A;  4HGM B;  2QM6 A;  4FIP B;  4F5U A;  2EFE A;  2DG5 A;  2I30 A;  2XSI A;  2XMO A;  3MHH B;  3MHS B;  2YDF A;  1UOR A;  5GIP A;  4ZBQ A;  1TXU A;  1KW2 A;  1KDX A;  3JQZ A;  1JNB A;  4NAW B;  4MBE C;  4F5V A;  5HOZ A; 
#chains in the Genus database with same CATH homology
 1GNJ A;  4GDX A;  2BXF A;  3M99 C;  4BKE A;  4FJC B;  2ROH A;  4J2V A;  2LOQ A;  1MIW A;  2XVQ A;  2Z8K A;  4ZBR A;  3H3A A;  3NMU A;  4DHX B;  3A73 A;  1BKE A;  1MIV A;  2NQO A;  3SQJ A;  3W1S A;  2AJE A;  1E7E A;  3KJL A;  2XVV A;  4W4U B;  1MA9 A;  4F5T A;  4OTT A;  4FK5 B;  2BXG A;  1E7F A;  1HK1 A;  4G03 A;  4LUH A;  5ID9 A;  3NVI A;  4IW2 A;  1HK2 A;  1NT2 B;  3V09 A;  4TQ0 A;  3PLA A;  1E7B A;  2BX8 A;  5BPK A;  1E78 A;  2XVU A;  4L9Q A;  1KXP D;  1H9Z A;  4IW1 A;  2Z8I A;  4LB9 A;  2I2Z A;  4N0U D;  5IJE A;  2E0Y A;  1FOU A;  2XVW A;  3WHS A;  4BY9 C;  3FWC C;  4G04 A;  1GNI A;  3GQX A;  3H37 A;  3FNM A;  4WA6 B;  2BXQ A;  2EFC A;  2JUH A;  5IFO A;  2DBX A;  4OR0 A;  3LU8 A;  3TDL A;  4M70 B;  4LUF A;  5GHK A;  2VUE A;  2VDB A;  4N3Z A;  4GDL B;  4ZC6 A;  1TF0 A;  3WHQ A;  2EFH A;  2DYO A;  5IIX A;  5DBY A;  2XW0 A;  5D7G A;  1VZS A;  3JRY A;  1MIY A;  3FWB C;  4LB2 A;  5ID7 A;  4G01 A;  4ZUX V;  2OT3 A;  2BXI A;  4L9K A;  2BXM A;  3G9K D;  2KBZ A;  1BJ5 A;  3B9M A;  3VQI A;  5B5T A;  4EMX A;  3B9L A;  1E7I A;  3SIU B;  1N5U A;  4OTU A;  4L8U A;  4S1Y A;  1AO6 A;  2NNW A;  1J7E A;  3GQU A;  4Z69 A;  4JK4 A;  3KIK A;  4F5S A;  3ICX A;  4GG2 A;  4LA0 A;  1HA2 A;  2BXO A;  1VFI A;  4C31 B;  4TQ1 A;  2BXH A;  4N0F D;  5DQF A;  2XW1 A;  4PO0 A;  2OZB B;  1HK5 A;  3GA9 L;  2E0X A;  4K2C A;  5GIO A;  1J78 A;  2CKX A;  5IIU A;  3UIV A;  4ZCG A;  2EFD A;  2BXL A;  3V03 A;  2VUF A;  2BXD A;  3LU6 A;  1LOT A;  3WHR A;  5GIN A;  4K71 A;  5IJF A;  1E7H A;  2DBW A;  3NVK A;  2BXK A;  4GDK B;  2BXB A;  1E7A A;  2BXN A;  3CX9 A;  2BXE A;  2BXP A;  2Z8J A;  1E7G A;  4ZBK A;  4E99 A;  2BXA A;  3SIV B;  1HK4 A;  5IJ5 A;  1E7C A;  2BXC A;  2QMC A;  4OT2 A;  1LNS A;  5FUO A;  2QHB A;  3NVM A;  4HGK A;  5IIH A;  2V36 A;  1BM0 A;  3A75 A;  1HK3 A;  2DBU A;  4Z9O A;  3V08 A;  1IJG A;  3LU7 A;  1O9X A;  1H5W A;  2DYM A;  4HGM B;  2QM6 A;  4FIP B;  4F5U A;  2EFE A;  2DG5 A;  2I30 A;  2XSI A;  2XMO A;  3MHH B;  3MHS B;  2YDF A;  1UOR A;  5GIP A;  4ZBQ A;  1TXU A;  1KW2 A;  3JQZ A;  1JNB A;  4NAW B;  4MBE C;  4F5V A;  5HOZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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