1E7C | Genus

Total Genus 214

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	214
sequence length	582
structure length	582
Chain Sequence	HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Plasma protein
source organism	Homo sapiens
publication title	Binding of the General Anesthetics Propofol and Halothane to Human Serum Albumin. High Resolution Crystal Structures pubmed doi rcsb
molecule keywords	SERUM ALBUMIN
total genus	214
structure length	582
sequence length	582
ec nomenclature
pdb deposition date	2000-08-26

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00273	Serum_albumin	Serum albumin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e7cA03
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e7cA02
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e7cA04
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e7cA01
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e7cA06
1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin; Chain A, Domain 1	Serum Albumin; Chain A, Domain 1	1e7cA05

1KW2A 4LB2A 1E7AA 4K71A 3LU7A 4LA0A 1E7GA 3V09A 2XW1A 2XVWA 3B9MA 1BJ5A 5ID7A 5DQFA 5IJEA 2BXCA 1LOTA 4BKEA 4IW1A 2BXPA 2BXEA 4HGKA 2BX8A 2XVQA 5HOZA 2I2ZA 2XVVA 1TF0A 3UIVA 1E7CA 1O9XA 1GNJA 4G03A 3V08A 4F5TA 3JRYA 1HA2A 1E78A 1HK4A 2BXIA 4L9KA 2BXOA 5IFOA 4ZBQA 1E7FA 3LU8A 1BM0A 1UORA 2BXNA 4J2VA 2BXLA 5GHKA 1KXPD 2BXKA 4HGMB 3TDLA 2BXQA 2XVUA 5IIHA 1HK5A 1N5UA 4LUHA 2BXDA 4LB9A 2BXHA 5IIXA 1HK2A 1GNIA 5IIUA 4F5UA 1J7EA 3V03A 1AO6A 4L9QA 2I30A 4IW2A 4N0UD 5DBYA 4EMXA 4E99A 2YDFA 2XSIA 2BXMA 3JQZA 1BKEA 1E7IA 1H9ZA 4G04A 4K2CA 1E7BA 1HK3A 3A73A 4ZBRA 2BXBA 3SQJA 5IJFA 1J78A 4OT2A 3B9LA 4PO0A 2BXAA 4S1YA 1E7HA 3CX9A 4F5VA 5ID9A 5IJ5A 4LUFA 2VDBA 5FUOA 4Z69A 1E7EA 2VUFA 3LU6A 2BXFA 4OR0A 2BXGA 2XW0A 4JK4A 4N0FD 4F5SA 1MA9A 1HK1A 4L8UA 2VUEA
chains in the Genus database with same CATH superfamily

1KW2A 4LB2A 1E7AA 4K71A 3LU7A 4WA6B 4LA0A 2CKXA 1E7GA 1SB0A 3A75A 2XW1A 3V09A 5GINA 3SIUB 2QMCA 2XVWA 3B9MA 2OT3A 1BJ5A 2DBWA 2XMOA 5ID7A 1MUHA 5DQFA 4ZC6A 5IJEA 2BXCA 1LOTA 3NVMA 2E0YA 1MIVA 2Z8IA 3BPJA 4BKEA 4IW1A 4W4UB 2LXSA 2LQIA 2BXPA 2BXEA 2BX8A 4HGKA 1MUSA 4GDLB 2EFHA 2XVQA 1H5WA 4I9OA 5HOZA 2I2ZA 3WHSA 2XVVA 1JNBA 1TF0A 4N3ZA 3UIVA 1E7CA 4G01A 1O9XA 1GNJA 4G03A 3H3AA 4ZBKA 3V08A 4F5TA 1HA2A 1E78A 3JRYA 5BPKA 1HK4A 2BXIA 3WHRA 2DYOA 3FNMA 2DYMA 2LQHA 4L9KA 2AGHB 2BXOA 3H37A 5IFOA 4ZBQA 1E7FA 3LU8A 4TQ1A 1BM0A 1UORA 2BXNA 4J2VA 2BXLA 5GHKA 1KXPD 3KIKA 2BXKA 4HGMB 3TDLA 4BY9C 2BXQA 4GG2A 5B5TA 2XVUA 4FIPB 2Z8JA 5IIHA 4OTTA 2V36A 3MHHB 1HK5A 1FOUA 2JUHA 1N5UA 2LXTA 4DM0A 4LUHA 2BXDA 2AJEA 4LB9A 3G9KD 2BXHA 4GDXA 5IIXA 3GQUA 2Z8KA 1HK2A 1GNIA 2OZBB 2QM6A 5GIOA 5IIUA 4F5UA 1J7EA 3V03A 1AO6A 4ZCGA 4L9QA 2I30A 4IW2A 4GDKB 2NNWA 4Z9OA 4N0UD 1TXUA 5DBYA 4D7XA 3MHSB 4EMXA 1MM8A 4DHXB 4E99A 2E0XA 5D7GA 3VQIA 3NMUA 2YDFA 4MBEC 3WHQA 2XSIA 3SIVB 2BXMA 3JQZA 4TQ0A 1BKEA 1E7IA 3NVKA 1H9ZA 2ROHA 3ICXA 4G04A 2DBUA 4K2CA 1E7BA 5GIPA 2EFCA 1HK3A 2EFEA 3A73A 3GQXA 2DG5A 4FK5B 4M70B 4ZUXV 1KDXA 1MIWA 1VFIA 3GA9L 4ZBRA 2QHBA 2BXBA 3SQJA 5IJFA 2DBXA 1LNSA 2KWFA 3ECPA 1J78A 4OT2A 3B9LA 4C31B 4PO0A 2BXAA 2EFDA 4FJCB 4NAWB 4S1YA 1E7HA 3CX9A 1IJGA 3FWBC 4F5VA 5ID9A 5IJ5A 4LUFA 2VDBA 3W1SA 5FUOA 4Z69A 1E7EA 2VUFA 3LU6A 1VZSA 2BXFA 3M99C 2KBZA 4OTUA 3PLAA 4OR0A 2GUTA 2BXGA 2XW0A 4JK4A 4N0FD 3NVIA 2NQOA 4F5SA 3KJLA 2K0NA 1MA9A 1HK1A 3FWCC 1NT2B 4L8UA 2LOQA 1MIYA 2VUEA
chains in the Genus database with same CATH topology

1KW2A 4LB2A 1E7AA 4K71A 3LU7A 4WA6B 4LA0A 2CKXA 1E7GA 3A75A 3V09A 2XW1A 5GINA 3SIUB 2QMCA 2XVWA 3B9MA 2OT3A 1BJ5A 2DBWA 2XMOA 5ID7A 5DQFA 4ZC6A 5IJEA 2BXCA 1LOTA 3NVMA 2E0YA 1MIVA 2Z8IA 4BKEA 4IW1A 4W4UB 2BXPA 2BXEA 2BX8A 4HGKA 4GDLB 2EFHA 2XVQA 1H5WA 5HOZA 2I2ZA 3WHSA 2XVVA 1JNBA 1TF0A 4N3ZA 3UIVA 1E7CA 4G01A 1O9XA 1GNJA 4G03A 3H3AA 4ZBKA 3V08A 4F5TA 1HA2A 1E78A 3JRYA 5BPKA 1HK4A 2BXIA 3WHRA 2DYOA 3FNMA 2DYMA 4L9KA 2BXOA 3H37A 5IFOA 4ZBQA 1E7FA 3LU8A 4TQ1A 1BM0A 1UORA 2BXNA 4J2VA 2BXLA 5GHKA 1KXPD 3KIKA 2BXKA 4HGMB 3TDLA 4BY9C 2BXQA 4GG2A 5B5TA 2XVUA 4FIPB 2Z8JA 5IIHA 4OTTA 2V36A 3MHHB 1HK5A 1FOUA 2JUHA 1N5UA 4LUHA 2BXDA 2AJEA 4LB9A 3G9KD 2BXHA 4GDXA 5IIXA 3GQUA 2Z8KA 1HK2A 1GNIA 2OZBB 2QM6A 5GIOA 5IIUA 4F5UA 1J7EA 3V03A 1AO6A 4ZCGA 4L9QA 2I30A 4IW2A 4GDKB 2NNWA 4Z9OA 4N0UD 1TXUA 5DBYA 4EMXA 3MHSB 4DHXB 4E99A 2E0XA 5D7GA 3VQIA 3NMUA 2YDFA 4MBEC 3WHQA 2XSIA 3SIVB 2BXMA 3JQZA 4TQ0A 1BKEA 1E7IA 3NVKA 1H9ZA 2ROHA 3ICXA 4G04A 2DBUA 4K2CA 1E7BA 5GIPA 2EFCA 1HK3A 2EFEA 3A73A 3GQXA 2DG5A 4FK5B 4M70B 4ZUXV 1MIWA 1VFIA 3GA9L 4ZBRA 2QHBA 2BXBA 3SQJA 5IJFA 2DBXA 1LNSA 1J78A 4OT2A 3B9LA 4C31B 4PO0A 2BXAA 2EFDA 4FJCB 4NAWB 4S1YA 1E7HA 3CX9A 1IJGA 3FWBC 4F5VA 5ID9A 5IJ5A 4LUFA 2VDBA 3W1SA 5FUOA 4Z69A 1E7EA 2VUFA 3LU6A 1VZSA 2BXFA 3M99C 2KBZA 4OTUA 3PLAA 4OR0A 2BXGA 2XW0A 4JK4A 4N0FD 3NVIA 2NQOA 4F5SA 3KJLA 1MA9A 1HK1A 3FWCC 1NT2B 4L8UA 2LOQA 1MIYA 2VUEA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1KW2 A;  4LB2 A;  1E7A A;  4K71 A;  3LU7 A;  4LA0 A;  1E7G A;  3V09 A;  2XW1 A;  2XVW A;  3B9M A;  1BJ5 A;  5ID7 A;  5DQF A;  5IJE A;  2BXC A;  1LOT A;  4BKE A;  4IW1 A;  2BXP A;  2BXE A;  4HGK A;  2BX8 A;  2XVQ A;  5HOZ A;  2I2Z A;  2XVV A;  1TF0 A;  3UIV A;  1E7C A;  1O9X A;  1GNJ A;  4G03 A;  3V08 A;  4F5T A;  3JRY A;  1HA2 A;  1E78 A;  1HK4 A;  2BXI A;  4L9K A;  2BXO A;  5IFO A;  4ZBQ A;  1E7F A;  3LU8 A;  1BM0 A;  1UOR A;  2BXN A;  4J2V A;  2BXL A;  5GHK A;  1KXP D;  2BXK A;  4HGM B;  3TDL A;  2BXQ A;  2XVU A;  5IIH A;  1HK5 A;  1N5U A;  4LUH A;  2BXD A;  4LB9 A;  2BXH A;  5IIX A;  1HK2 A;  1GNI A;  5IIU A;  4F5U A;  1J7E A;  3V03 A;  1AO6 A;  4L9Q A;  2I30 A;  4IW2 A;  4N0U D;  5DBY A;  4EMX A;  4E99 A;  2YDF A;  2XSI A;  2BXM A;  3JQZ A;  1BKE A;  1E7I A;  1H9Z A;  4G04 A;  4K2C A;  1E7B A;  1HK3 A;  3A73 A;  4ZBR A;  2BXB A;  3SQJ A;  5IJF A;  1J78 A;  4OT2 A;  3B9L A;  4PO0 A;  2BXA A;  4S1Y A;  1E7H A;  3CX9 A;  4F5V A;  5ID9 A;  5IJ5 A;  4LUF A;  2VDB A;  5FUO A;  4Z69 A;  1E7E A;  2VUF A;  3LU6 A;  2BXF A;  4OR0 A;  2BXG A;  2XW0 A;  4JK4 A;  4N0F D;  4F5S A;  1MA9 A;  1HK1 A;  4L8U A;  2VUE A; 
#chains in the Genus database with same CATH topology
 1KW2 A;  4LB2 A;  1E7A A;  4K71 A;  3LU7 A;  4WA6 B;  4LA0 A;  2CKX A;  1E7G A;  1SB0 A;  3A75 A;  2XW1 A;  3V09 A;  5GIN A;  3SIU B;  2QMC A;  2XVW A;  3B9M A;  2OT3 A;  1BJ5 A;  2DBW A;  2XMO A;  5ID7 A;  1MUH A;  5DQF A;  4ZC6 A;  5IJE A;  2BXC A;  1LOT A;  3NVM A;  2E0Y A;  1MIV A;  2Z8I A;  3BPJ A;  4BKE A;  4IW1 A;  4W4U B;  2LXS A;  2LQI A;  2BXP A;  2BXE A;  2BX8 A;  4HGK A;  1MUS A;  4GDL B;  2EFH A;  2XVQ A;  1H5W A;  4I9O A;  5HOZ A;  2I2Z A;  3WHS A;  2XVV A;  1JNB A;  1TF0 A;  4N3Z A;  3UIV A;  1E7C A;  4G01 A;  1O9X A;  1GNJ A;  4G03 A;  3H3A A;  4ZBK A;  3V08 A;  4F5T A;  1HA2 A;  1E78 A;  3JRY A;  5BPK A;  1HK4 A;  2BXI A;  3WHR A;  2DYO A;  3FNM A;  2DYM A;  2LQH A;  4L9K A;  2AGH B;  2BXO A;  3H37 A;  5IFO A;  4ZBQ A;  1E7F A;  3LU8 A;  4TQ1 A;  1BM0 A;  1UOR A;  2BXN A;  4J2V A;  2BXL A;  5GHK A;  1KXP D;  3KIK A;  2BXK A;  4HGM B;  3TDL A;  4BY9 C;  2BXQ A;  4GG2 A;  5B5T A;  2XVU A;  4FIP B;  2Z8J A;  5IIH A;  4OTT A;  2V36 A;  3MHH B;  1HK5 A;  1FOU A;  2JUH A;  1N5U A;  2LXT A;  4DM0 A;  4LUH A;  2BXD A;  2AJE A;  4LB9 A;  3G9K D;  2BXH A;  4GDX A;  5IIX A;  3GQU A;  2Z8K A;  1HK2 A;  1GNI A;  2OZB B;  2QM6 A;  5GIO A;  5IIU A;  4F5U A;  1J7E A;  3V03 A;  1AO6 A;  4ZCG A;  4L9Q A;  2I30 A;  4IW2 A;  4GDK B;  2NNW A;  4Z9O A;  4N0U D;  1TXU A;  5DBY A;  4D7X A;  3MHS B;  4EMX A;  1MM8 A;  4DHX B;  4E99 A;  2E0X A;  5D7G A;  3VQI A;  3NMU A;  2YDF A;  4MBE C;  3WHQ A;  2XSI A;  3SIV B;  2BXM A;  3JQZ A;  4TQ0 A;  1BKE A;  1E7I A;  3NVK A;  1H9Z A;  2ROH A;  3ICX A;  4G04 A;  2DBU A;  4K2C A;  1E7B A;  5GIP A;  2EFC A;  1HK3 A;  2EFE A;  3A73 A;  3GQX A;  2DG5 A;  4FK5 B;  4M70 B;  4ZUX V;  1KDX A;  1MIW A;  1VFI A;  3GA9 L;  4ZBR A;  2QHB A;  2BXB A;  3SQJ A;  5IJF A;  2DBX A;  1LNS A;  2KWF A;  3ECP A;  1J78 A;  4OT2 A;  3B9L A;  4C31 B;  4PO0 A;  2BXA A;  2EFD A;  4FJC B;  4NAW B;  4S1Y A;  1E7H A;  3CX9 A;  1IJG A;  3FWB C;  4F5V A;  5ID9 A;  5IJ5 A;  4LUF A;  2VDB A;  3W1S A;  5FUO A;  4Z69 A;  1E7E A;  2VUF A;  3LU6 A;  1VZS A;  2BXF A;  3M99 C;  2KBZ A;  4OTU A;  3PLA A;  4OR0 A;  2GUT A;  2BXG A;  2XW0 A;  4JK4 A;  4N0F D;  3NVI A;  2NQO A;  4F5S A;  3KJL A;  2K0N A;  1MA9 A;  1HK1 A;  3FWC C;  1NT2 B;  4L8U A;  2LOQ A;  1MIY A;  2VUE A; 
#chains in the Genus database with same CATH homology
 1KW2 A;  4LB2 A;  1E7A A;  4K71 A;  3LU7 A;  4WA6 B;  4LA0 A;  2CKX A;  1E7G A;  3A75 A;  3V09 A;  2XW1 A;  5GIN A;  3SIU B;  2QMC A;  2XVW A;  3B9M A;  2OT3 A;  1BJ5 A;  2DBW A;  2XMO A;  5ID7 A;  5DQF A;  4ZC6 A;  5IJE A;  2BXC A;  1LOT A;  3NVM A;  2E0Y A;  1MIV A;  2Z8I A;  4BKE A;  4IW1 A;  4W4U B;  2BXP A;  2BXE A;  2BX8 A;  4HGK A;  4GDL B;  2EFH A;  2XVQ A;  1H5W A;  5HOZ A;  2I2Z A;  3WHS A;  2XVV A;  1JNB A;  1TF0 A;  4N3Z A;  3UIV A;  1E7C A;  4G01 A;  1O9X A;  1GNJ A;  4G03 A;  3H3A A;  4ZBK A;  3V08 A;  4F5T A;  1HA2 A;  1E78 A;  3JRY A;  5BPK A;  1HK4 A;  2BXI A;  3WHR A;  2DYO A;  3FNM A;  2DYM A;  4L9K A;  2BXO A;  3H37 A;  5IFO A;  4ZBQ A;  1E7F A;  3LU8 A;  4TQ1 A;  1BM0 A;  1UOR A;  2BXN A;  4J2V A;  2BXL A;  5GHK A;  1KXP D;  3KIK A;  2BXK A;  4HGM B;  3TDL A;  4BY9 C;  2BXQ A;  4GG2 A;  5B5T A;  2XVU A;  4FIP B;  2Z8J A;  5IIH A;  4OTT A;  2V36 A;  3MHH B;  1HK5 A;  1FOU A;  2JUH A;  1N5U A;  4LUH A;  2BXD A;  2AJE A;  4LB9 A;  3G9K D;  2BXH A;  4GDX A;  5IIX A;  3GQU A;  2Z8K A;  1HK2 A;  1GNI A;  2OZB B;  2QM6 A;  5GIO A;  5IIU A;  4F5U A;  1J7E A;  3V03 A;  1AO6 A;  4ZCG A;  4L9Q A;  2I30 A;  4IW2 A;  4GDK B;  2NNW A;  4Z9O A;  4N0U D;  1TXU A;  5DBY A;  4EMX A;  3MHS B;  4DHX B;  4E99 A;  2E0X A;  5D7G A;  3VQI A;  3NMU A;  2YDF A;  4MBE C;  3WHQ A;  2XSI A;  3SIV B;  2BXM A;  3JQZ A;  4TQ0 A;  1BKE A;  1E7I A;  3NVK A;  1H9Z A;  2ROH A;  3ICX A;  4G04 A;  2DBU A;  4K2C A;  1E7B A;  5GIP A;  2EFC A;  1HK3 A;  2EFE A;  3A73 A;  3GQX A;  2DG5 A;  4FK5 B;  4M70 B;  4ZUX V;  1MIW A;  1VFI A;  3GA9 L;  4ZBR A;  2QHB A;  2BXB A;  3SQJ A;  5IJF A;  2DBX A;  1LNS A;  1J78 A;  4OT2 A;  3B9L A;  4C31 B;  4PO0 A;  2BXA A;  2EFD A;  4FJC B;  4NAW B;  4S1Y A;  1E7H A;  3CX9 A;  1IJG A;  3FWB C;  4F5V A;  5ID9 A;  5IJ5 A;  4LUF A;  2VDB A;  3W1S A;  5FUO A;  4Z69 A;  1E7E A;  2VUF A;  3LU6 A;  1VZS A;  2BXF A;  3M99 C;  2KBZ A;  4OTU A;  3PLA A;  4OR0 A;  2BXG A;  2XW0 A;  4JK4 A;  4N0F D;  3NVI A;  2NQO A;  4F5S A;  3KJL A;  1MA9 A;  1HK1 A;  3FWC C;  1NT2 B;  4L8U A;  2LOQ A;  1MIY A;  2VUE A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1E7CA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations