1H9ZA

Human serum albumin complexed with myristic acid and the r-(+) enantiomer of warfarin
Total Genus 224
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure Analysis of Warfarin Binding to Human Serum Albumin: Anatomy of Drug Site I
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords SERUM ALBUMIN
total genus 224
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2001-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA05
1N5UA 3CX9A 1GNJA 1TF0A 2XW0A 4EMXA 2BXQA 1HK4A 4IW2A 4OT2A 2BXLA 2XVVA 3UIVA 2VDBA 4LA0A 1E7FA 4L9QA 4LB9A 4LUHA 5ID9A 2BXGA 4L9KA 4HGKA 2I2ZA 5IJFA 2BXFA 2XW1A 4J2VA 1HK1A 4ZBQA 4Z69A 1E7EA 5ID7A 1H9ZA 1KXPD 2BXMA 3B9MA 3JRYA 4JK4A 2YDFA 1AO6A 3SQJA 1BKEA 1E78A 4E99A 4IW1A 5DQFA 4ZBRA 1GNIA 1E7BA 1E7IA 4F5TA 1J78A 1O9XA 5DBYA 2XVQA 4G04A 4L8UA 4F5UA 2BXKA 2BXBA 5IJEA 4K71A 4N0FD 5FUOA 1BM0A 2I30A 4G03A 4S1YA 1HK5A 1HK2A 4BKEA 2BXHA 5IIHA 2BXOA 2XVWA 1LOTA 1E7HA 1HK3A 2XVUA 3LU6A 2BXEA 4PO0A 4F5VA 4LUFA 1E7CA 3A73A 2BXNA 4LB2A 4HGMB 2BX8A 5IIUA 1MA9A 3TDLA 5IJ5A 3LU7A 3JQZA 5IIXA 1KW2A 1E7GA 1UORA 1HA2A 5GHKA 4OR0A 1J7EA 1E7AA 2BXIA 2XSIA 3V09A 3V08A 2BXDA 4K2CA 1BJ5A 3B9LA 5HOZA 5IFOA 4F5SA 2VUFA 3V03A 2BXAA 2VUEA 3LU8A 2BXPA 4N0UD 2BXCA
chains in the Genus database with same CATH superfamily
1N5UA 5GIPA 4C31B 3CX9A 1JNBA 2XMOA 2LQIA 1GNJA 4GG2A 4NAWB 1TF0A 2DYOA 4ZC6A 2XW0A 4ZBKA 3BPJA 2EFCA 4EMXA 2OZBB 2BXQA 2EFDA 3MHHB 1HK4A 4IW2A 4GDKB 4OT2A 3GA9L 1VFIA 2BXLA 2Z8IA 2LXTA 4FJCB 2LXSA 2XVVA 3UIVA 2VDBA 4LA0A 3NVIA 1E7FA 1MUSA 4L9QA 4LB9A 4LUHA 4GDXA 5ID9A 4N3ZA 3FWBC 2BXGA 2E0XA 4L9KA 1MUHA 4HGKA 2I2ZA 5IJFA 2BXFA 2XW1A 4J2VA 3ECPA 1HK1A 1FOUA 3MHSB 1E7EA 4ZBQA 4Z69A 4ZCGA 2V36A 5ID7A 4DHXB 1TXUA 1VZSA 3H3AA 1KDXA 1H9ZA 2DBWA 1KXPD 2DYMA 2BXMA 3M99C 3B9MA 3JRYA 1H5WA 4JK4A 1MIVA 2YDFA 1AO6A 3FNMA 3SQJA 1BKEA 1E78A 4E99A 4IW1A 5DQFA 4ZBRA 5GINA 1GNIA 3VQIA 5GIOA 2AJEA 3ICXA 1E7BA 1E7IA 2EFHA 4OTUA 4F5TA 4ZUXV 1J78A 1O9XA 2JUHA 5DBYA 2XVQA 4OTTA 2LQHA 2DG5A 1LNSA 4G04A 3WHQA 3FWCC 4L8UA 4F5UA 2BXKA 2DBUA 4MBEC 2KBZA 2BXBA 5IJEA 4K71A 3H37A 4DM0A 3NVKA 3G9KD 4N0FD 1MIWA 1SB0A 5FUOA 1BM0A 1MIYA 2GUTA 2I30A 4G03A 4S1YA 1HK5A 1IJGA 1HK2A 3W1SA 4BY9C 4BKEA 4M70B 4I9OA 4GDLB 2LOQA 2CKXA 2BXHA 1NT2B 3SIUB 5IIHA 3PLAA 2BXOA 2XVWA 3SIVB 2Z8KA 2AGHB 1LOTA 1MM8A 1E7HA 1HK3A 2XVUA 2Z8JA 3KJLA 3LU6A 2BXEA 2KWFA 4FK5B 4PO0A 4F5VA 4LUFA 1E7CA 4FIPB 2ROHA 3A75A 3A73A 2NNWA 2BXNA 4LB2A 4HGMB 2BX8A 5IIUA 1MA9A 3TDLA 5IJ5A 2NQOA 2QM6A 3JQZA 3LU7A 1KW2A 4TQ1A 1E7GA 5IIXA 1UORA 1HA2A 2QHBA 2DBXA 5GHKA 4OR0A 5B5TA 1J7EA 4WA6B 1E7AA 2BXIA 2XSIA 3V09A 3V08A 4D7XA 3WHSA 2BXDA 5BPKA 4K2CA 1BJ5A 3B9LA 5HOZA 2QMCA 5IFOA 2EFEA 2VUFA 4F5SA 5D7GA 4Z9OA 4W4UB 3WHRA 3NMUA 3KIKA 4G01A 2OT3A 3V03A 3NVMA 3GQXA 2BXAA 2VUEA 4TQ0A 3LU8A 2K0NA 2BXPA 2E0YA 3GQUA 4N0UD 2BXCA
chains in the Genus database with same CATH topology
1N5UA 5GIPA 4C31B 3CX9A 1JNBA 2XMOA 4GG2A 1GNJA 4NAWB 1TF0A 2DYOA 4ZC6A 2XW0A 4ZBKA 2EFCA 4EMXA 2OZBB 2BXQA 2EFDA 3MHHB 1HK4A 4IW2A 4GDKB 4OT2A 3GA9L 1VFIA 2BXLA 2Z8IA 4FJCB 2XVVA 3UIVA 2VDBA 4LA0A 3NVIA 1E7FA 4L9QA 4LB9A 4LUHA 4GDXA 5ID9A 4N3ZA 3FWBC 2BXGA 2E0XA 4L9KA 4HGKA 2I2ZA 5IJFA 2BXFA 2XW1A 4J2VA 1HK1A 1FOUA 3MHSB 1E7EA 4ZBQA 4Z69A 4ZCGA 2V36A 5ID7A 4DHXB 1TXUA 1VZSA 3H3AA 1H9ZA 2DBWA 1KXPD 2DYMA 2BXMA 3M99C 3B9MA 3JRYA 1H5WA 4JK4A 1MIVA 2YDFA 1AO6A 3FNMA 3SQJA 1BKEA 1E78A 4E99A 4IW1A 5DQFA 4ZBRA 5GINA 1GNIA 3VQIA 5GIOA 2AJEA 3ICXA 1E7BA 1E7IA 2EFHA 4OTUA 4F5TA 4ZUXV 1J78A 1O9XA 2JUHA 5DBYA 2XVQA 4OTTA 2DG5A 1LNSA 4G04A 3WHQA 3FWCC 4L8UA 4F5UA 2BXKA 2DBUA 4MBEC 2KBZA 2BXBA 5IJEA 4K71A 3H37A 3NVKA 3G9KD 4N0FD 1MIWA 5FUOA 1BM0A 1MIYA 2I30A 4G03A 4S1YA 1HK5A 1IJGA 1HK2A 3W1SA 4BY9C 4BKEA 4M70B 4GDLB 2LOQA 2CKXA 2BXHA 1NT2B 3SIUB 5IIHA 3PLAA 2BXOA 2XVWA 3SIVB 2Z8KA 1LOTA 1E7HA 1HK3A 2XVUA 2Z8JA 3KJLA 3LU6A 2BXEA 4FK5B 4PO0A 4F5VA 4LUFA 1E7CA 4FIPB 2ROHA 3A75A 3A73A 2NNWA 2BXNA 4LB2A 4HGMB 2BX8A 5IIUA 1MA9A 3TDLA 5IJ5A 2NQOA 2QM6A 3JQZA 3LU7A 1KW2A 4TQ1A 1E7GA 5IIXA 1UORA 1HA2A 2QHBA 2DBXA 5GHKA 4OR0A 5B5TA 1J7EA 4WA6B 1E7AA 2BXIA 2XSIA 3V09A 3V08A 3WHSA 2BXDA 5BPKA 4K2CA 1BJ5A 3B9LA 5HOZA 2QMCA 5IFOA 2EFEA 2VUFA 4F5SA 5D7GA 4Z9OA 4W4UB 3WHRA 3NMUA 3KIKA 4G01A 2OT3A 3V03A 3NVMA 3GQXA 2BXAA 2VUEA 4TQ0A 3LU8A 2BXPA 2E0YA 3GQUA 4N0UD 2BXCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N5U A;  3CX9 A;  1GNJ A;  1TF0 A;  2XW0 A;  4EMX A;  2BXQ A;  1HK4 A;  4IW2 A;  4OT2 A;  2BXL A;  2XVV A;  3UIV A;  2VDB A;  4LA0 A;  1E7F A;  4L9Q A;  4LB9 A;  4LUH A;  5ID9 A;  2BXG A;  4L9K A;  4HGK A;  2I2Z A;  5IJF A;  2BXF A;  2XW1 A;  4J2V A;  1HK1 A;  4ZBQ A;  4Z69 A;  1E7E A;  5ID7 A;  1H9Z A;  1KXP D;  2BXM A;  3B9M A;  3JRY A;  4JK4 A;  2YDF A;  1AO6 A;  3SQJ A;  1BKE A;  1E78 A;  4E99 A;  4IW1 A;  5DQF A;  4ZBR A;  1GNI A;  1E7B A;  1E7I A;  4F5T A;  1J78 A;  1O9X A;  5DBY A;  2XVQ A;  4G04 A;  4L8U A;  4F5U A;  2BXK A;  2BXB A;  5IJE A;  4K71 A;  4N0F D;  5FUO A;  1BM0 A;  2I30 A;  4G03 A;  4S1Y A;  1HK5 A;  1HK2 A;  4BKE A;  2BXH A;  5IIH A;  2BXO A;  2XVW A;  1LOT A;  1E7H A;  1HK3 A;  2XVU A;  3LU6 A;  2BXE A;  4PO0 A;  4F5V A;  4LUF A;  1E7C A;  3A73 A;  2BXN A;  4LB2 A;  4HGM B;  2BX8 A;  5IIU A;  1MA9 A;  3TDL A;  5IJ5 A;  3LU7 A;  3JQZ A;  5IIX A;  1KW2 A;  1E7G A;  1UOR A;  1HA2 A;  5GHK A;  4OR0 A;  1J7E A;  1E7A A;  2BXI A;  2XSI A;  3V09 A;  3V08 A;  2BXD A;  4K2C A;  1BJ5 A;  3B9L A;  5HOZ A;  5IFO A;  4F5S A;  2VUF A;  3V03 A;  2BXA A;  2VUE A;  3LU8 A;  2BXP A;  4N0U D;  2BXC A; 
#chains in the Genus database with same CATH topology
 1N5U A;  5GIP A;  4C31 B;  3CX9 A;  1JNB A;  2XMO A;  2LQI A;  1GNJ A;  4GG2 A;  4NAW B;  1TF0 A;  2DYO A;  4ZC6 A;  2XW0 A;  4ZBK A;  3BPJ A;  2EFC A;  4EMX A;  2OZB B;  2BXQ A;  2EFD A;  3MHH B;  1HK4 A;  4IW2 A;  4GDK B;  4OT2 A;  3GA9 L;  1VFI A;  2BXL A;  2Z8I A;  2LXT A;  4FJC B;  2LXS A;  2XVV A;  3UIV A;  2VDB A;  4LA0 A;  3NVI A;  1E7F A;  1MUS A;  4L9Q A;  4LB9 A;  4LUH A;  4GDX A;  5ID9 A;  4N3Z A;  3FWB C;  2BXG A;  2E0X A;  4L9K A;  1MUH A;  4HGK A;  2I2Z A;  5IJF A;  2BXF A;  2XW1 A;  4J2V A;  3ECP A;  1HK1 A;  1FOU A;  3MHS B;  1E7E A;  4ZBQ A;  4Z69 A;  4ZCG A;  2V36 A;  5ID7 A;  4DHX B;  1TXU A;  1VZS A;  3H3A A;  1KDX A;  1H9Z A;  2DBW A;  1KXP D;  2DYM A;  2BXM A;  3M99 C;  3B9M A;  3JRY A;  1H5W A;  4JK4 A;  1MIV A;  2YDF A;  1AO6 A;  3FNM A;  3SQJ A;  1BKE A;  1E78 A;  4E99 A;  4IW1 A;  5DQF A;  4ZBR A;  5GIN A;  1GNI A;  3VQI A;  5GIO A;  2AJE A;  3ICX A;  1E7B A;  1E7I A;  2EFH A;  4OTU A;  4F5T A;  4ZUX V;  1J78 A;  1O9X A;  2JUH A;  5DBY A;  2XVQ A;  4OTT A;  2LQH A;  2DG5 A;  1LNS A;  4G04 A;  3WHQ A;  3FWC C;  4L8U A;  4F5U A;  2BXK A;  2DBU A;  4MBE C;  2KBZ A;  2BXB A;  5IJE A;  4K71 A;  3H37 A;  4DM0 A;  3NVK A;  3G9K D;  4N0F D;  1MIW A;  1SB0 A;  5FUO A;  1BM0 A;  1MIY A;  2GUT A;  2I30 A;  4G03 A;  4S1Y A;  1HK5 A;  1IJG A;  1HK2 A;  3W1S A;  4BY9 C;  4BKE A;  4M70 B;  4I9O A;  4GDL B;  2LOQ A;  2CKX A;  2BXH A;  1NT2 B;  3SIU B;  5IIH A;  3PLA A;  2BXO A;  2XVW A;  3SIV B;  2Z8K A;  2AGH B;  1LOT A;  1MM8 A;  1E7H A;  1HK3 A;  2XVU A;  2Z8J A;  3KJL A;  3LU6 A;  2BXE A;  2KWF A;  4FK5 B;  4PO0 A;  4F5V A;  4LUF A;  1E7C A;  4FIP B;  2ROH A;  3A75 A;  3A73 A;  2NNW A;  2BXN A;  4LB2 A;  4HGM B;  2BX8 A;  5IIU A;  1MA9 A;  3TDL A;  5IJ5 A;  2NQO A;  2QM6 A;  3JQZ A;  3LU7 A;  1KW2 A;  4TQ1 A;  1E7G A;  5IIX A;  1UOR A;  1HA2 A;  2QHB A;  2DBX A;  5GHK A;  4OR0 A;  5B5T A;  1J7E A;  4WA6 B;  1E7A A;  2BXI A;  2XSI A;  3V09 A;  3V08 A;  4D7X A;  3WHS A;  2BXD A;  5BPK A;  4K2C A;  1BJ5 A;  3B9L A;  5HOZ A;  2QMC A;  5IFO A;  2EFE A;  2VUF A;  4F5S A;  5D7G A;  4Z9O A;  4W4U B;  3WHR A;  3NMU A;  3KIK A;  4G01 A;  2OT3 A;  3V03 A;  3NVM A;  3GQX A;  2BXA A;  2VUE A;  4TQ0 A;  3LU8 A;  2K0N A;  2BXP A;  2E0Y A;  3GQU A;  4N0U D;  2BXC A; 
#chains in the Genus database with same CATH homology
 1N5U A;  5GIP A;  4C31 B;  3CX9 A;  1JNB A;  2XMO A;  4GG2 A;  1GNJ A;  4NAW B;  1TF0 A;  2DYO A;  4ZC6 A;  2XW0 A;  4ZBK A;  2EFC A;  4EMX A;  2OZB B;  2BXQ A;  2EFD A;  3MHH B;  1HK4 A;  4IW2 A;  4GDK B;  4OT2 A;  3GA9 L;  1VFI A;  2BXL A;  2Z8I A;  4FJC B;  2XVV A;  3UIV A;  2VDB A;  4LA0 A;  3NVI A;  1E7F A;  4L9Q A;  4LB9 A;  4LUH A;  4GDX A;  5ID9 A;  4N3Z A;  3FWB C;  2BXG A;  2E0X A;  4L9K A;  4HGK A;  2I2Z A;  5IJF A;  2BXF A;  2XW1 A;  4J2V A;  1HK1 A;  1FOU A;  3MHS B;  1E7E A;  4ZBQ A;  4Z69 A;  4ZCG A;  2V36 A;  5ID7 A;  4DHX B;  1TXU A;  1VZS A;  3H3A A;  1H9Z A;  2DBW A;  1KXP D;  2DYM A;  2BXM A;  3M99 C;  3B9M A;  3JRY A;  1H5W A;  4JK4 A;  1MIV A;  2YDF A;  1AO6 A;  3FNM A;  3SQJ A;  1BKE A;  1E78 A;  4E99 A;  4IW1 A;  5DQF A;  4ZBR A;  5GIN A;  1GNI A;  3VQI A;  5GIO A;  2AJE A;  3ICX A;  1E7B A;  1E7I A;  2EFH A;  4OTU A;  4F5T A;  4ZUX V;  1J78 A;  1O9X A;  2JUH A;  5DBY A;  2XVQ A;  4OTT A;  2DG5 A;  1LNS A;  4G04 A;  3WHQ A;  3FWC C;  4L8U A;  4F5U A;  2BXK A;  2DBU A;  4MBE C;  2KBZ A;  2BXB A;  5IJE A;  4K71 A;  3H37 A;  3NVK A;  3G9K D;  4N0F D;  1MIW A;  5FUO A;  1BM0 A;  1MIY A;  2I30 A;  4G03 A;  4S1Y A;  1HK5 A;  1IJG A;  1HK2 A;  3W1S A;  4BY9 C;  4BKE A;  4M70 B;  4GDL B;  2LOQ A;  2CKX A;  2BXH A;  1NT2 B;  3SIU B;  5IIH A;  3PLA A;  2BXO A;  2XVW A;  3SIV B;  2Z8K A;  1LOT A;  1E7H A;  1HK3 A;  2XVU A;  2Z8J A;  3KJL A;  3LU6 A;  2BXE A;  4FK5 B;  4PO0 A;  4F5V A;  4LUF A;  1E7C A;  4FIP B;  2ROH A;  3A75 A;  3A73 A;  2NNW A;  2BXN A;  4LB2 A;  4HGM B;  2BX8 A;  5IIU A;  1MA9 A;  3TDL A;  5IJ5 A;  2NQO A;  2QM6 A;  3JQZ A;  3LU7 A;  1KW2 A;  4TQ1 A;  1E7G A;  5IIX A;  1UOR A;  1HA2 A;  2QHB A;  2DBX A;  5GHK A;  4OR0 A;  5B5T A;  1J7E A;  4WA6 B;  1E7A A;  2BXI A;  2XSI A;  3V09 A;  3V08 A;  3WHS A;  2BXD A;  5BPK A;  4K2C A;  1BJ5 A;  3B9L A;  5HOZ A;  2QMC A;  5IFO A;  2EFE A;  2VUF A;  4F5S A;  5D7G A;  4Z9O A;  4W4U B;  3WHR A;  3NMU A;  3KIK A;  4G01 A;  2OT3 A;  3V03 A;  3NVM A;  3GQX A;  2BXA A;  2VUE A;  4TQ0 A;  3LU8 A;  2BXP A;  2E0Y A;  3GQU A;  4N0U D;  2BXC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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