1H9ZA

Human serum albumin complexed with myristic acid and the r-(+) enantiomer of warfarin
Total Genus 224
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
source organism Homo sapiens
publication title Crystal Structure Analysis of Warfarin Binding to Human Serum Albumin: Anatomy of Drug Site I
pubmed doi rcsb
molecule keywords SERUM ALBUMIN
total genus 224
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2001-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 1h9zA05
4G04A 4OT2A 2BXDA 4IW1A 5FUOA 3JQZA 1E7BA 4LUFA 4LB9A 1N5UA 3UIVA 4S1YA 2BXLA 3TDLA 3B9MA 4E99A 1J78A 1E7GA 2BXAA 5ID7A 1O9XA 4BKEA 2XVQA 3V03A 5ID9A 4HGMB 5IJ5A 1BM0A 4EMXA 1HK3A 4N0FD 3V08A 2BXKA 1E7FA 4LUHA 1KW2A 5IFOA 3LU8A 2YDFA 4K71A 3JRYA 2BX8A 4JK4A 2VUFA 1AO6A 1E78A 1HA2A 1E7HA 1BKEA 5IJEA 5HOZA 1E7EA 3V09A 3SQJA 3A73A 2XVVA 1BJ5A 2BXHA 4K2CA 4L9QA 1LOTA 2BXBA 2BXPA 2XW0A 1GNJA 4ZBRA 1UORA 5GHKA 1E7CA 1GNIA 1KXPD 1HK1A 4HGKA 2BXGA 1E7IA 2I30A 2BXNA 2BXMA 2BXEA 1HK2A 2BXQA 4LB2A 5DQFA 1HK5A 4IW2A 4N0UD 2VUEA 1H9ZA 5IIXA 2VDBA 4PO0A 2BXIA 5IIUA 4J2VA 1E7AA 4F5SA 4F5TA 2BXFA 2XVUA 3LU6A 3LU7A 3B9LA 2XW1A 3CX9A 4LA0A 4G03A 4ZBQA 1HK4A 4OR0A 2BXCA 4F5VA 4Z69A 4L8UA 2BXOA 1MA9A 5IJFA 4F5UA 2XVWA 5DBYA 1TF0A 4L9KA 5IIHA 2XSIA 2I2ZA 1J7EA
chains in the Genus database with same CATH superfamily
4G04A 4OT2A 2E0YA 2BXDA 4IW1A 5FUOA 2QMCA 2EFHA 2LOQA 2LQHA 3JQZA 2NQOA 4FJCB 1E7BA 4LUFA 2E0XA 4N3ZA 3ICXA 2DBUA 3PLAA 1MM8A 2DBWA 2CKXA 1MIVA 4LB9A 2DYOA 1N5UA 3UIVA 4ZCGA 4S1YA 2QHBA 2BXLA 3TDLA 3B9MA 3SIVB 4E99A 4OTUA 1J78A 1FOUA 1E7GA 3WHRA 4WA6B 2BXAA 2NNWA 5ID7A 1O9XA 4G01A 2LQIA 4BKEA 5GIOA 2XVQA 3V03A 5ID9A 4HGMB 1IJGA 5IJ5A 5B5TA 1BM0A 4EMXA 3FWBC 3VQIA 1HK3A 4GDKB 4N0FD 3V08A 2BXKA 4D7XA 1E7FA 4LUHA 1KW2A 3G9KD 5IFOA 3LU8A 4GDLB 1NT2B 1TXUA 4W4UB 2K0NA 2YDFA 4K71A 4MBEC 3JRYA 4TQ1A 2OT3A 2Z8JA 5GIPA 4BY9C 2BX8A 2QM6A 4I9OA 2OZBB 1MIYA 3NVKA 2EFDA 4JK4A 2Z8KA 3GQUA 2VUFA 3KIKA 4ZBKA 1MUSA 4C31B 1AO6A 1E78A 4M70B 4ZC6A 4DM0A 1HA2A 3M99C 1E7HA 1BKEA 2ROHA 2Z8IA 1MUHA 5IJEA 5HOZA 2XMOA 1E7EA 3V09A 4GDXA 3SQJA 3A73A 2DG5A 3FWCC 2XVVA 1BJ5A 2BXHA 3KJLA 4K2CA 2KBZA 1LOTA 2BXBA 2BXPA 4L9QA 2XW0A 1GNJA 4ZUXV 3NVMA 4ZBRA 3H37A 4GG2A 3GQXA 1UORA 4DHXB 3MHHB 4OTTA 5GHKA 3FNMA 3SIUB 3H3AA 3W1SA 1E7CA 1GNIA 1KXPD 1JNBA 1HK1A 4HGKA 2BXGA 1E7IA 2I30A 2BXNA 2BXMA 2BXEA 2V36A 1HK2A 2DBXA 2BXQA 4LB2A 5DQFA 2EFCA 1HK5A 4IW2A 4N0UD 2LXTA 2VUEA 3ECPA 1H9ZA 3GA9L 2GUTA 5IIXA 2VDBA 4PO0A 2BXIA 4TQ0A 5GINA 5IIUA 4J2VA 1E7AA 2EFEA 4F5TA 2BXFA 2XVUA 3LU6A 4F5SA 3NMUA 3A75A 3LU7A 5D7GA 3B9LA 2XW1A 1MIWA 3CX9A 3MHSB 4Z9OA 4LA0A 1SB0A 4FK5B 1H5WA 2AGHB 4G03A 4ZBQA 1HK4A 5BPKA 1KDXA 2JUHA 1VFIA 2AJEA 4OR0A 2KWFA 4FIPB 4NAWB 3NVIA 2DYMA 2BXCA 2LXSA 3WHSA 1LNSA 4F5VA 4L8UA 1VZSA 1MA9A 2BXOA 3WHQA 4F5UA 2XVWA 5DBYA 4Z69A 5IJFA 1TF0A 4L9KA 5IIHA 2XSIA 3BPJA 2I2ZA 1J7EA
chains in the Genus database with same CATH topology
4G04A 4OT2A 2E0YA 2BXDA 4IW1A 5FUOA 2QMCA 2EFHA 2LOQA 3JQZA 2NQOA 4FJCB 1E7BA 4LUFA 2E0XA 4N3ZA 3ICXA 2DBUA 3PLAA 2DBWA 2CKXA 1MIVA 4LB9A 2DYOA 1N5UA 3UIVA 4ZCGA 4S1YA 2QHBA 2BXLA 3TDLA 3B9MA 3SIVB 4E99A 4OTUA 1J78A 1FOUA 1E7GA 3WHRA 4WA6B 2BXAA 2NNWA 5ID7A 1O9XA 4G01A 4BKEA 5GIOA 2XVQA 3V03A 5ID9A 4HGMB 1IJGA 5IJ5A 5B5TA 1BM0A 4EMXA 3FWBC 3VQIA 1HK3A 4GDKB 4N0FD 3V08A 2BXKA 1E7FA 4LUHA 1KW2A 3G9KD 5IFOA 3LU8A 4GDLB 1NT2B 1TXUA 4W4UB 2YDFA 4K71A 4TQ1A 4MBEC 3JRYA 2OT3A 2Z8JA 5GIPA 4BY9C 2BX8A 2QM6A 2OZBB 1MIYA 3NVKA 2EFDA 4JK4A 2Z8KA 3GQUA 2VUFA 3KIKA 4ZBKA 4C31B 1AO6A 1E78A 4M70B 4ZC6A 1HA2A 3M99C 1E7HA 1BKEA 2ROHA 2Z8IA 5IJEA 5HOZA 2XMOA 1E7EA 3V09A 4GDXA 3SQJA 3A73A 2DG5A 3FWCC 2XVVA 1BJ5A 2BXHA 3KJLA 4K2CA 2KBZA 1LOTA 2BXBA 2BXPA 4L9QA 2XW0A 1GNJA 4ZUXV 3NVMA 4ZBRA 3H37A 4GG2A 3GQXA 1UORA 4DHXB 3MHHB 4OTTA 5GHKA 3FNMA 3SIUB 3H3AA 3W1SA 1E7CA 1GNIA 1KXPD 1JNBA 1HK1A 4HGKA 2BXGA 1E7IA 2I30A 2BXNA 2BXMA 2BXEA 2V36A 1HK2A 2DBXA 2BXQA 4LB2A 5DQFA 2EFCA 1HK5A 4IW2A 4N0UD 2VUEA 1H9ZA 3GA9L 5IIXA 2VDBA 4PO0A 2BXIA 4TQ0A 5GINA 5IIUA 4J2VA 1E7AA 2EFEA 4F5TA 2BXFA 2XVUA 3LU6A 4F5SA 3NMUA 3A75A 3LU7A 5D7GA 3B9LA 2XW1A 1MIWA 3CX9A 3MHSB 4Z9OA 4LA0A 4FK5B 1H5WA 4G03A 4ZBQA 1HK4A 5BPKA 2JUHA 1VFIA 2AJEA 4OR0A 4FIPB 4NAWB 3NVIA 2DYMA 2BXCA 3WHSA 1LNSA 4F5VA 4L8UA 1VZSA 1MA9A 2BXOA 3WHQA 4F5UA 2XVWA 5DBYA 4Z69A 5IJFA 1TF0A 4L9KA 5IIHA 2XSIA 2I2ZA 1J7EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G04 A;  4OT2 A;  2BXD A;  4IW1 A;  5FUO A;  3JQZ A;  1E7B A;  4LUF A;  4LB9 A;  1N5U A;  3UIV A;  4S1Y A;  2BXL A;  3TDL A;  3B9M A;  4E99 A;  1J78 A;  1E7G A;  2BXA A;  5ID7 A;  1O9X A;  4BKE A;  2XVQ A;  3V03 A;  5ID9 A;  4HGM B;  5IJ5 A;  1BM0 A;  4EMX A;  1HK3 A;  4N0F D;  3V08 A;  2BXK A;  1E7F A;  4LUH A;  1KW2 A;  5IFO A;  3LU8 A;  2YDF A;  4K71 A;  3JRY A;  2BX8 A;  4JK4 A;  2VUF A;  1AO6 A;  1E78 A;  1HA2 A;  1E7H A;  1BKE A;  5IJE A;  5HOZ A;  1E7E A;  3V09 A;  3SQJ A;  3A73 A;  2XVV A;  1BJ5 A;  2BXH A;  4K2C A;  4L9Q A;  1LOT A;  2BXB A;  2BXP A;  2XW0 A;  1GNJ A;  4ZBR A;  1UOR A;  5GHK A;  1E7C A;  1GNI A;  1KXP D;  1HK1 A;  4HGK A;  2BXG A;  1E7I A;  2I30 A;  2BXN A;  2BXM A;  2BXE A;  1HK2 A;  2BXQ A;  4LB2 A;  5DQF A;  1HK5 A;  4IW2 A;  4N0U D;  2VUE A;  1H9Z A;  5IIX A;  2VDB A;  4PO0 A;  2BXI A;  5IIU A;  4J2V A;  1E7A A;  4F5S A;  4F5T A;  2BXF A;  2XVU A;  3LU6 A;  3LU7 A;  3B9L A;  2XW1 A;  3CX9 A;  4LA0 A;  4G03 A;  4ZBQ A;  1HK4 A;  4OR0 A;  2BXC A;  4F5V A;  4Z69 A;  4L8U A;  2BXO A;  1MA9 A;  5IJF A;  4F5U A;  2XVW A;  5DBY A;  1TF0 A;  4L9K A;  5IIH A;  2XSI A;  2I2Z A;  1J7E A; 
#chains in the Genus database with same CATH topology
 4G04 A;  4OT2 A;  2E0Y A;  2BXD A;  4IW1 A;  5FUO A;  2QMC A;  2EFH A;  2LOQ A;  2LQH A;  3JQZ A;  2NQO A;  4FJC B;  1E7B A;  4LUF A;  2E0X A;  4N3Z A;  3ICX A;  2DBU A;  3PLA A;  1MM8 A;  2DBW A;  2CKX A;  1MIV A;  4LB9 A;  2DYO A;  1N5U A;  3UIV A;  4ZCG A;  4S1Y A;  2QHB A;  2BXL A;  3TDL A;  3B9M A;  3SIV B;  4E99 A;  4OTU A;  1J78 A;  1FOU A;  1E7G A;  3WHR A;  4WA6 B;  2BXA A;  2NNW A;  5ID7 A;  1O9X A;  4G01 A;  2LQI A;  4BKE A;  5GIO A;  2XVQ A;  3V03 A;  5ID9 A;  4HGM B;  1IJG A;  5IJ5 A;  5B5T A;  1BM0 A;  4EMX A;  3FWB C;  3VQI A;  1HK3 A;  4GDK B;  4N0F D;  3V08 A;  2BXK A;  4D7X A;  1E7F A;  4LUH A;  1KW2 A;  3G9K D;  5IFO A;  3LU8 A;  4GDL B;  1NT2 B;  1TXU A;  4W4U B;  2K0N A;  2YDF A;  4K71 A;  4MBE C;  3JRY A;  4TQ1 A;  2OT3 A;  2Z8J A;  5GIP A;  4BY9 C;  2BX8 A;  2QM6 A;  4I9O A;  2OZB B;  1MIY A;  3NVK A;  2EFD A;  4JK4 A;  2Z8K A;  3GQU A;  2VUF A;  3KIK A;  4ZBK A;  1MUS A;  4C31 B;  1AO6 A;  1E78 A;  4M70 B;  4ZC6 A;  4DM0 A;  1HA2 A;  3M99 C;  1E7H A;  1BKE A;  2ROH A;  2Z8I A;  1MUH A;  5IJE A;  5HOZ A;  2XMO A;  1E7E A;  3V09 A;  4GDX A;  3SQJ A;  3A73 A;  2DG5 A;  3FWC C;  2XVV A;  1BJ5 A;  2BXH A;  3KJL A;  4K2C A;  2KBZ A;  1LOT A;  2BXB A;  2BXP A;  4L9Q A;  2XW0 A;  1GNJ A;  4ZUX V;  3NVM A;  4ZBR A;  3H37 A;  4GG2 A;  3GQX A;  1UOR A;  4DHX B;  3MHH B;  4OTT A;  5GHK A;  3FNM A;  3SIU B;  3H3A A;  3W1S A;  1E7C A;  1GNI A;  1KXP D;  1JNB A;  1HK1 A;  4HGK A;  2BXG A;  1E7I A;  2I30 A;  2BXN A;  2BXM A;  2BXE A;  2V36 A;  1HK2 A;  2DBX A;  2BXQ A;  4LB2 A;  5DQF A;  2EFC A;  1HK5 A;  4IW2 A;  4N0U D;  2LXT A;  2VUE A;  3ECP A;  1H9Z A;  3GA9 L;  2GUT A;  5IIX A;  2VDB A;  4PO0 A;  2BXI A;  4TQ0 A;  5GIN A;  5IIU A;  4J2V A;  1E7A A;  2EFE A;  4F5T A;  2BXF A;  2XVU A;  3LU6 A;  4F5S A;  3NMU A;  3A75 A;  3LU7 A;  5D7G A;  3B9L A;  2XW1 A;  1MIW A;  3CX9 A;  3MHS B;  4Z9O A;  4LA0 A;  1SB0 A;  4FK5 B;  1H5W A;  2AGH B;  4G03 A;  4ZBQ A;  1HK4 A;  5BPK A;  1KDX A;  2JUH A;  1VFI A;  2AJE A;  4OR0 A;  2KWF A;  4FIP B;  4NAW B;  3NVI A;  2DYM A;  2BXC A;  2LXS A;  3WHS A;  1LNS A;  4F5V A;  4L8U A;  1VZS A;  1MA9 A;  2BXO A;  3WHQ A;  4F5U A;  2XVW A;  5DBY A;  4Z69 A;  5IJF A;  1TF0 A;  4L9K A;  5IIH A;  2XSI A;  3BPJ A;  2I2Z A;  1J7E A; 
#chains in the Genus database with same CATH homology
 4G04 A;  4OT2 A;  2E0Y A;  2BXD A;  4IW1 A;  5FUO A;  2QMC A;  2EFH A;  2LOQ A;  3JQZ A;  2NQO A;  4FJC B;  1E7B A;  4LUF A;  2E0X A;  4N3Z A;  3ICX A;  2DBU A;  3PLA A;  2DBW A;  2CKX A;  1MIV A;  4LB9 A;  2DYO A;  1N5U A;  3UIV A;  4ZCG A;  4S1Y A;  2QHB A;  2BXL A;  3TDL A;  3B9M A;  3SIV B;  4E99 A;  4OTU A;  1J78 A;  1FOU A;  1E7G A;  3WHR A;  4WA6 B;  2BXA A;  2NNW A;  5ID7 A;  1O9X A;  4G01 A;  4BKE A;  5GIO A;  2XVQ A;  3V03 A;  5ID9 A;  4HGM B;  1IJG A;  5IJ5 A;  5B5T A;  1BM0 A;  4EMX A;  3FWB C;  3VQI A;  1HK3 A;  4GDK B;  4N0F D;  3V08 A;  2BXK A;  1E7F A;  4LUH A;  1KW2 A;  3G9K D;  5IFO A;  3LU8 A;  4GDL B;  1NT2 B;  1TXU A;  4W4U B;  2YDF A;  4K71 A;  4TQ1 A;  4MBE C;  3JRY A;  2OT3 A;  2Z8J A;  5GIP A;  4BY9 C;  2BX8 A;  2QM6 A;  2OZB B;  1MIY A;  3NVK A;  2EFD A;  4JK4 A;  2Z8K A;  3GQU A;  2VUF A;  3KIK A;  4ZBK A;  4C31 B;  1AO6 A;  1E78 A;  4M70 B;  4ZC6 A;  1HA2 A;  3M99 C;  1E7H A;  1BKE A;  2ROH A;  2Z8I A;  5IJE A;  5HOZ A;  2XMO A;  1E7E A;  3V09 A;  4GDX A;  3SQJ A;  3A73 A;  2DG5 A;  3FWC C;  2XVV A;  1BJ5 A;  2BXH A;  3KJL A;  4K2C A;  2KBZ A;  1LOT A;  2BXB A;  2BXP A;  4L9Q A;  2XW0 A;  1GNJ A;  4ZUX V;  3NVM A;  4ZBR A;  3H37 A;  4GG2 A;  3GQX A;  1UOR A;  4DHX B;  3MHH B;  4OTT A;  5GHK A;  3FNM A;  3SIU B;  3H3A A;  3W1S A;  1E7C A;  1GNI A;  1KXP D;  1JNB A;  1HK1 A;  4HGK A;  2BXG A;  1E7I A;  2I30 A;  2BXN A;  2BXM A;  2BXE A;  2V36 A;  1HK2 A;  2DBX A;  2BXQ A;  4LB2 A;  5DQF A;  2EFC A;  1HK5 A;  4IW2 A;  4N0U D;  2VUE A;  1H9Z A;  3GA9 L;  5IIX A;  2VDB A;  4PO0 A;  2BXI A;  4TQ0 A;  5GIN A;  5IIU A;  4J2V A;  1E7A A;  2EFE A;  4F5T A;  2BXF A;  2XVU A;  3LU6 A;  4F5S A;  3NMU A;  3A75 A;  3LU7 A;  5D7G A;  3B9L A;  2XW1 A;  1MIW A;  3CX9 A;  3MHS B;  4Z9O A;  4LA0 A;  4FK5 B;  1H5W A;  4G03 A;  4ZBQ A;  1HK4 A;  5BPK A;  2JUH A;  1VFI A;  2AJE A;  4OR0 A;  4FIP B;  4NAW B;  3NVI A;  2DYM A;  2BXC A;  3WHS A;  1LNS A;  4F5V A;  4L8U A;  1VZS A;  1MA9 A;  2BXO A;  3WHQ A;  4F5U A;  2XVW A;  5DBY A;  4Z69 A;  5IJF A;  1TF0 A;  4L9K A;  5IIH A;  2XSI A;  2I2Z A;  1J7E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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